Motif ID: PAX4.p2

Z-value: 0.850


Transcription factors associated with PAX4.p2:

Gene SymbolEntrez IDGene Name
PAX4 5078 paired box 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
PAX4chr7_-_127255574-0.125.7e-01Click!


Activity profile for motif PAX4.p2.

activity profile for motif PAX4.p2


Sorted Z-values histogram for motif PAX4.p2

Sorted Z-values for motif PAX4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_102979096 1.671 NM_003855
IL18R1
interleukin 18 receptor 1
chr2_-_136873740 1.244 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr10_-_116286570 1.203 ABLIM1
actin binding LIM protein 1
chr6_+_17282931 1.041 NM_153020
RBM24
RNA binding motif protein 24
chr20_+_62184372 0.975 NM_024059
C20orf195
chromosome 20 open reading frame 195
chr20_-_23062786 0.969 CD93
CD93 molecule
chr1_-_182357757 0.953 GLUL
glutamate-ammonia ligase
chr4_+_140587086 0.928 MGST2
microsomal glutathione S-transferase 2
chr4_+_140586921 0.910 NM_001204366
NM_001204367
NM_001204368
NM_002413
MGST2



microsomal glutathione S-transferase 2



chr7_+_80267922 0.880 CD36
CD36 molecule (thrombospondin receptor)
chr1_+_145524989 0.878 NM_003637
ITGA10
integrin, alpha 10
chr9_-_16870719 0.836 NM_017637
BNC2
basonuclin 2
chr6_-_130031278 0.819 NM_033515
ARHGAP18
Rho GTPase activating protein 18
chr1_-_182357871 0.800 GLUL
glutamate-ammonia ligase
chr11_+_114166534 0.795 NM_006169
NNMT
nicotinamide N-methyltransferase
chr1_+_212788359 0.786 NM_001206486
ATF3
activating transcription factor 3
chr5_-_142783059 0.763 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_+_55034633 0.759 SAMD4A
sterile alpha motif domain containing 4A
chr11_+_65271145 0.757


chr7_-_86595203 0.754 NM_152748
KIAA1324L
KIAA1324-like
chr3_+_111805174 0.740 NM_001171747
NM_024616
C3orf52

chromosome 3 open reading frame 52

chr3_-_112358510 0.711 CCDC80
coiled-coil domain containing 80
chr20_-_18810838 0.700 NM_001242671
LOC100128496
uncharacterized LOC100128496
chr7_+_128312345 0.682 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chr6_-_31697953 0.676 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr9_-_123676849 0.636 NM_001190947
TRAF1
TNF receptor-associated factor 1
chr3_-_112358758 0.634 CCDC80
coiled-coil domain containing 80
chr6_-_31698033 0.630 NM_013974
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr18_-_65182507 0.619 DSEL
dermatan sulfate epimerase-like
chr1_-_182360181 0.617 GLUL
glutamate-ammonia ligase
chr4_+_39184023 0.607 NM_025132
WDR19
WD repeat domain 19
chr10_+_35426709 0.590 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr2_+_12856813 0.586 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr7_+_80267972 0.583 CD36
CD36 molecule (thrombospondin receptor)
chr3_+_9975513 0.568 NM_015513
NM_001031717
NM_001077415
CRELD1


cysteine-rich with EGF-like domains 1


chr10_-_116286661 0.561 NM_006720
ABLIM1
actin binding LIM protein 1
chr11_-_62472901 0.558


chr1_+_152881022 0.545 NM_005547
IVL
involucrin
chr18_-_53089722 0.543 NM_001243233
TCF4
transcription factor 4
chr15_+_67418053 0.536 NM_001145102
SMAD3
SMAD family member 3
chr11_-_114466397 0.533 FAM55D
family with sequence similarity 55, member D
chr20_-_34117447 0.513 NM_001145350
C20orf173
chromosome 20 open reading frame 173
chr4_+_492988 0.508 NM_001127178
NM_017733
PIGG

phosphatidylinositol glycan anchor biosynthesis, class G

chr19_+_50015535 0.496 NM_001136019
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr3_-_112359251 0.480 CCDC80
coiled-coil domain containing 80
chr4_-_186877869 0.474 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr9_+_79115548 0.468 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr11_-_18610182 0.467 NM_001040697
NM_018314
UEVLD

UEV and lactate/malate dehyrogenase domains

chr5_+_139027868 0.463 CXXC5
CXXC finger protein 5
chr17_-_71088820 0.459 SLC39A11
solute carrier family 39 (metal ion transporter), member 11
chrX_+_47004663 0.454 RBM10
RNA binding motif protein 10
chr10_+_5136613 0.454 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr3_+_9476506 0.451


chr12_-_9268440 0.449 A2M
alpha-2-macroglobulin
chrX_+_47004657 0.449 RBM10
RNA binding motif protein 10
chr2_-_191184770 0.442 NM_014362
NM_198047
HIBCH

3-hydroxyisobutyryl-CoA hydrolase

chr2_+_170550949 0.439 NM_001199290
NM_001008489
NM_001199285
NM_001199286
NM_001199287
NM_001199288
PHOSPHO2-KLHL23
PHOSPHO2




PHOSPHO2-KLHL23 readthrough
phosphatase, orphan 2




chr2_-_191184485 0.438 HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr17_-_71088814 0.438 SLC39A11
solute carrier family 39 (metal ion transporter), member 11
chr16_+_71879893 0.426 NM_001137675
ATXN1L
ataxin 1-like
chr17_-_71088831 0.423 SLC39A11
solute carrier family 39 (metal ion transporter), member 11
chr1_-_182360889 0.423 GLUL
glutamate-ammonia ligase
chr8_+_41348126 0.422 NM_001002296
GOLGA7
golgin A7
chrX_+_47004665 0.414 RBM10
RNA binding motif protein 10
chrX_+_47004633 0.410 RBM10
RNA binding motif protein 10
chr17_-_46799879 0.405 NM_032391
PRAC
prostate cancer susceptibility candidate
chr14_+_55738871 0.404 NM_152231
FBXO34
F-box protein 34
chrX_+_47004670 0.401 RBM10
RNA binding motif protein 10
chr2_-_136875629 0.397 NM_003467
CXCR4
chemokine (C-X-C motif) receptor 4
chrX_+_47004676 0.397 RBM10
RNA binding motif protein 10
chr10_+_5136589 0.396 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr5_+_76382458 0.391 LOC728723
uncharacterized LOC728723
chr7_+_133812051 0.391 NM_144648
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr2_-_208489695 0.390 NM_145280
METTL21A
methyltransferase like 21A
chr8_+_41348105 0.388 GOLGA7
golgin A7
chrX_-_99986496 0.387 NM_001174068
NM_080737
SYTL4

synaptotagmin-like 4

chr17_-_71088832 0.385 NM_001159770
NM_139177
SLC39A11

solute carrier family 39 (metal ion transporter), member 11

chr19_-_37064102 0.385 ZNF529
zinc finger protein 529
chr11_-_66115016 0.384 NM_006876
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr11_+_44785975 0.380 NM_130783
TSPAN18
tetraspanin 18
chr12_+_105153258 0.380 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr10_+_35484829 0.376 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr4_-_113206883 0.369 NM_052864
TIFA
TRAF-interacting protein with forkhead-associated domain
chr5_+_139027955 0.368 CXXC5
CXXC finger protein 5
chr15_+_63340314 0.366 NM_001018008
TPM1
tropomyosin 1 (alpha)
chrX_+_47004693 0.364 RBM10
RNA binding motif protein 10
chr10_+_5136556 0.360 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr8_+_41348094 0.356 GOLGA7
golgin A7
chr8_+_90770201 0.353 RIPK2
receptor-interacting serine-threonine kinase 2
chr13_-_114898013 0.347 RASA3
RAS p21 protein activator 3
chr5_-_175395544 0.342 NM_032361
THOC3
THO complex 3
chr3_+_69134057 0.338 NM_006407
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr2_+_217498205 0.331 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr4_+_41614725 0.330 LIMCH1
LIM and calponin homology domains 1
chr14_-_100842637 0.328 WARS
tryptophanyl-tRNA synthetase
chr5_-_93447237 0.328 NM_001163417
NM_001163418
NM_032042
FAM172A


family with sequence similarity 172, member A


chr2_+_203879562 0.327 NM_001114132
NBEAL1
neurobeachin-like 1
chrX_+_47004619 0.326 RBM10
RNA binding motif protein 10
chr12_+_10365415 0.326 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chrX_+_110187468 0.325 NM_001128166
NM_001128167
PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

chrX_+_47004609 0.325 NM_001204466
NM_001204467
NM_001204468
NM_005676
NM_152856
RBM10




RNA binding motif protein 10




chr18_-_53255734 0.322 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr10_+_77542518 0.316 NM_032024
C10orf11
chromosome 10 open reading frame 11
chr9_-_70178814 0.314 NM_001126334
FOXD4L5
forkhead box D4-like 5
chr9_+_42717233 0.313 NM_001099279
NM_199244
FOXD4L2
FOXD4L4
forkhead box D4-like 2
forkhead box D4-like 4
chr2_+_231860838 0.311 NM_139073
SPATA3
spermatogenesis associated 3
chr11_-_62474666 0.310 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr19_+_15052298 0.308 NM_012377
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chr11_-_124622133 0.307 VSIG2
V-set and immunoglobulin domain containing 2
chr14_+_76618289 0.303 C14orf118
chromosome 14 open reading frame 118
chr10_+_114709963 0.302 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr3_+_51895644 0.302 NM_203424
IQCF2
IQ motif containing F2
chr11_-_62474869 0.300 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr16_+_70148213 0.299 PDPR
pyruvate dehydrogenase phosphatase regulatory subunit
chr9_-_111882203 0.297 C9orf5
chromosome 9 open reading frame 5
chr2_-_88285308 0.295 NM_001024457
RGPD1
RANBP2-like and GRIP domain containing 1
chr11_-_74109417 0.294 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chr1_+_32042085 0.294 NM_001204414
NM_022164
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr3_+_45067750 0.292 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr6_+_126240369 0.292 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr11_-_78052925 0.290 NM_012296
GAB2
GRB2-associated binding protein 2
chr11_-_62474810 0.289 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr2_+_202004997 0.289 NM_001202515
CFLAR
CASP8 and FADD-like apoptosis regulator
chr7_+_69064316 0.287 AUTS2
autism susceptibility candidate 2
chr9_+_6215785 0.287 NM_001199640
NM_001199641
NM_033439
IL33


interleukin 33


chr7_+_80267782 0.278 NM_000072
NM_001001548
CD36

CD36 molecule (thrombospondin receptor)

chr17_-_41738901 0.276 NM_004527
NM_013999
MEOX1

mesenchyme homeobox 1

chr1_+_12123433 0.273 NM_001243
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr9_-_69202203 0.273 NM_001085476
FOXD4L6
forkhead box D4-like 6
chr19_+_11708234 0.273 NM_145295
ZNF627
zinc finger protein 627
chr8_+_41348067 0.273 NM_001174124
NM_016099
GOLGA7

golgin A7

chr2_+_217498082 0.272 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr5_+_139027907 0.269 CXXC5
CXXC finger protein 5
chr2_-_218843541 0.269 TNS1
tensin 1
chr20_-_31239558 0.268 NM_182584
C20orf203
chromosome 20 open reading frame 203
chr1_-_166845533 0.266 NM_053053
TADA1
transcriptional adaptor 1
chr12_+_56546203 0.266 NM_001199629
NM_002475
MYL6B

myosin, light chain 6B, alkali, smooth muscle and non-muscle

chr8_-_38854025 0.264 NM_001024380
NM_001024381
NM_031940
NM_078473
TM2D2



TM2 domain containing 2



chr22_-_31688329 0.262 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr7_+_100728719 0.261 NM_030961
TRIM56
tripartite motif containing 56
chr19_-_37064195 0.259 NM_020951
ZNF529
zinc finger protein 529
chr12_-_29937691 0.259 NM_175861
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr14_-_100842623 0.258 WARS
tryptophanyl-tRNA synthetase
chr5_-_125930604 0.257 NM_001182
NM_001201377
NM_001202404
ALDH7A1


aldehyde dehydrogenase 7 family, member A1


chr11_+_72975569 0.256 NM_176796
NM_176797
P2RY6

pyrimidinergic receptor P2Y, G-protein coupled, 6

chr15_-_50411405 0.256 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4
chr11_+_120107348 0.256 NM_001244682
POU2F3
POU class 2 homeobox 3
chr8_-_38854001 0.254 TM2D2
TM2 domain containing 2
chr8_-_99129323 0.251 HRSP12
heat-responsive protein 12
chr1_-_154928564 0.248 NM_020524
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr1_-_150669499 0.247 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr18_+_29769986 0.246 NM_005925
MEP1B
meprin A, beta
chr22_-_43411156 0.243 NM_001184970
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr13_-_114898057 0.243 RASA3
RAS p21 protein activator 3
chr12_+_32112381 0.242 C12orf35
chromosome 12 open reading frame 35
chr1_-_150241409 0.241 NM_001077628
NM_001243771
NM_001243772
NM_016022
APH1A



anterior pharynx defective 1 homolog A (C. elegans)



chr3_-_17741511 0.238 NM_001134381
TBC1D5
TBC1 domain family, member 5
chr6_+_144612872 0.238 NM_007124
UTRN
utrophin
chr7_+_72848108 0.237 NM_003508
FZD9
frizzled family receptor 9
chr16_+_70147528 0.237 NM_017990
PDPR
pyruvate dehydrogenase phosphatase regulatory subunit
chr1_-_154928595 0.236 PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr15_-_40401041 0.236 NM_001003940
BMF
Bcl2 modifying factor
chr22_+_29449877 0.234 ZNRF3
zinc and ring finger 3
chr9_-_112191105 0.233 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr15_-_23086842 0.232 NM_001142275
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr13_-_39564857 0.230 NM_001144033
NM_145286
STOML3

stomatin (EPB72)-like 3

chr4_+_30722445 0.229 PCDH7
protocadherin 7
chr5_-_175394949 0.229 THOC3
THO complex 3
chr21_+_19289656 0.228 NM_001204175
NM_001204176
NM_001204177
NM_001204178
CHODL



chondrolectin



chr11_+_12960793 0.226 TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr6_+_134758840 0.226 LOC154092
uncharacterized LOC154092
chr6_-_137494719 0.223 NM_052962
NM_181309
NM_181310
IL22RA2


interleukin 22 receptor, alpha 2


chr11_+_125034604 0.222 PKNOX2
PBX/knotted 1 homeobox 2
chr10_+_6186758 0.222 NM_001145443
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr11_+_26353677 0.219 NM_031418
ANO3
anoctamin 3
chr7_+_93551015 0.219 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr1_+_53527723 0.218 NM_001199080
NM_001199082
NM_153703
PODN


podocan


chr10_+_95326397 0.218 NM_001195755
NM_181745
O3FAR1

omega-3 fatty acid receptor 1

chr3_-_17782398 0.217 NM_014744
TBC1D5
TBC1 domain family, member 5
chr4_+_41614933 0.216 LIMCH1
LIM and calponin homology domains 1
chr8_-_82395401 0.216 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr5_-_95158465 0.215 NM_001118890
NM_001243658
NM_001243659
NM_002064
GLRX



glutaredoxin (thioltransferase)



chrX_+_55744049 0.214 NM_006064
NM_016656
RRAGB

Ras-related GTP binding B

chr6_-_42713783 0.213 TBCC
tubulin folding cofactor C
chr3_+_38307297 0.213 NM_004256
SLC22A13
solute carrier family 22 (organic anion transporter), member 13
chr7_-_33080517 0.210 NM_001166118
NM_016489
NT5C3

5'-nucleotidase, cytosolic III

chr1_+_43766565 0.205 NM_001253357
NM_005424
TIE1

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

chr7_-_137686812 0.204 CREB3L2
cAMP responsive element binding protein 3-like 2
chr12_-_12291374 0.204 LRP6
low density lipoprotein receptor-related protein 6
chr3_+_186739643 0.203 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr17_+_7384720 0.203 NM_001102614
SLC35G6
solute carrier family 35, member G6
chr2_+_102770401 0.201 NM_000877
IL1R1
interleukin 1 receptor, type I
chr5_-_142783225 0.200 NM_000176
NM_001020825
NM_001024094
NM_001204258
NM_001204259
NM_001204260
NM_001204261
NM_001204262
NM_001204263
NM_001204264
NM_001204265
NR3C1










nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)










chr14_-_100842676 0.199 NM_173701
NM_213645
WARS

tryptophanyl-tRNA synthetase

chr11_+_65268313 0.198 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr11_-_133715368 0.198 NM_174927
SPATA19
spermatogenesis associated 19
chr12_+_123942650 0.197 NM_022717
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr3_+_194406614 0.197 NM_153690
FAM43A
family with sequence similarity 43, member A
chr3_-_71632741 0.192 NM_001244808
NM_001012505
NM_001244810
NM_032682
FOXP1



forkhead box P1



chr1_-_150978879 0.192 NM_001163259
NM_001163260
NM_001040217
FAM63A


family with sequence similarity 63, member A



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.13 2.76e-03 GO:0009987 cellular process

Nothing significant found in compartment category.

Nothing significant found in function category.