Motif ID: PPARG.p2

Z-value: 0.585


Transcription factors associated with PPARG.p2:

Gene SymbolEntrez IDGene Name
PPARG 5468 peroxisome proliferator-activated receptor gamma

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
PPARGchr3_+_12330336-0.135.3e-01Click!


Activity profile for motif PPARG.p2.

activity profile for motif PPARG.p2


Sorted Z-values histogram for motif PPARG.p2

Sorted Z-values for motif PPARG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PPARG.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_49669404 0.942 TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr16_+_90168671 0.655 FAM157C
family with sequence similarity 157, member C
chr8_-_127570710 0.653 NM_174911
FAM84B
family with sequence similarity 84, member B
chr1_+_203274646 0.640 NM_006763
BTG2
BTG family, member 2
chr8_-_9009050 0.634 NM_001201329
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr19_-_13213669 0.630 LYL1
lymphoblastic leukemia derived sequence 1
chr10_-_99052429 0.601 NM_001204300
NM_032900
ARHGAP19

Rho GTPase activating protein 19

chr10_-_99052358 0.599 ARHGAP19
Rho GTPase activating protein 19
chr10_-_99052391 0.523 ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 readthrough
Rho GTPase activating protein 19
chr10_-_116418056 0.520 NM_002313
ABLIM1
actin binding LIM protein 1
chr6_-_52441815 0.513 NM_012288
TRAM2
translocation associated membrane protein 2
chr1_+_16083132 0.510 FBLIM1
filamin binding LIM protein 1
chr11_+_9779832 0.461 LOC283104
uncharacterized LOC283104
chr7_-_100425035 0.455 NM_004444
EPHB4
EPH receptor B4
chr16_-_3627353 0.441 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr19_+_18451365 0.430 NM_017712
PGPEP1
pyroglutamyl-peptidase I
chr6_-_52441714 0.363 TRAM2
translocation associated membrane protein 2
chr7_-_134854225 0.349 NM_001243753
NM_001243755
C7orf49

chromosome 7 open reading frame 49

chr3_-_122512526 0.331 NM_024610
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr1_-_160254923 0.328 NM_001193644
NM_002857
PEX19

peroxisomal biogenesis factor 19

chr12_-_56583301 0.326 NM_001130420
NM_003075
NM_139067
SMARCC2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2


chr6_-_112575880 0.323 LAMA4
laminin, alpha 4
chr19_-_55740631 0.319 NM_173804
TMEM86B
transmembrane protein 86B
chr19_+_42388445 0.317 NM_199002
ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr20_-_271303 0.307 NM_080571
NM_153269
C20orf96

chromosome 20 open reading frame 96

chr5_+_167956545 0.301


chr16_+_8768403 0.300 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr1_+_201798281 0.298 NM_018085
IPO9
importin 9
chr13_+_33160610 0.297 PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr2_+_219283809 0.291 NM_007127
VIL1
villin 1
chr20_-_62610990 0.279 NM_080621
SAMD10
sterile alpha motif domain containing 10
chr10_+_102758072 0.279 LZTS2
leucine zipper, putative tumor suppressor 2
chr7_+_30951414 0.273 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr6_-_112575766 0.263 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
LAMA4




laminin, alpha 4




chr1_+_92495484 0.257 NM_173567
EPHX4
epoxide hydrolase 4
chr4_+_87856152 0.255 NM_001166693
AFF1
AF4/FMR2 family, member 1
chr1_-_160254910 0.253 PEX19
peroxisomal biogenesis factor 19
chr8_-_127570465 0.249 FAM84B
family with sequence similarity 84, member B
chr17_-_62097937 0.244 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr12_+_109915461 0.239 UBE3B
ubiquitin protein ligase E3B
chr7_+_75932865 0.235 HSPB1
heat shock 27kDa protein 1
chr22_+_29702950 0.232 NM_006478
NM_152236
NM_152237
GAS2L1


growth arrest-specific 2 like 1


chr12_+_109915430 0.228 NM_130466
NM_183415
UBE3B

ubiquitin protein ligase E3B

chr8_+_144816287 0.223 LOC100128338
uncharacterized LOC100128338
chr17_-_39728304 0.218 NM_000226
KRT9
keratin 9
chr7_+_1577118 0.216 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr16_+_82068958 0.214 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr8_-_101118170 0.211 RGS22
regulator of G-protein signaling 22
chr7_+_75932992 0.209 HSPB1
heat shock 27kDa protein 1
chr9_+_79056581 0.209 NM_001097634
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr1_-_236228382 0.203 NID1
nidogen 1
chr1_-_6526150 0.202 NM_001039664
NM_003790
NM_148965
NM_148966
NM_148967
NM_148970
TNFRSF25





tumor necrosis factor receptor superfamily, member 25





chr9_-_130524696 0.200 NM_001142532
NM_001142531
SH2D3C

SH2 domain containing 3C

chr17_+_48172100 0.194 NM_001199898
PDK2
pyruvate dehydrogenase kinase, isozyme 2
chr19_+_49660997 0.192 NM_001195227
NM_017636
TRPM4

transient receptor potential cation channel, subfamily M, member 4

chr12_-_52585686 0.189 NM_001081492
NM_182507
KRT80

keratin 80

chr11_+_2923559 0.188 SLC22A18
solute carrier family 22, member 18
chr10_+_114135965 0.186 ACSL5
acyl-CoA synthetase long-chain family member 5
chr15_-_74753490 0.184 NM_032907
NM_201265
UBL7

ubiquitin-like 7 (bone marrow stromal cell-derived)

chr10_+_114135937 0.181 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr15_-_74753431 0.179 UBL7
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr19_+_49128208 0.178 NM_001204160
SPHK2
sphingosine kinase 2
chr6_-_112575708 0.175 LAMA4
laminin, alpha 4
chr11_+_2923528 0.174 SLC22A18
solute carrier family 22, member 18
chr8_+_145722108 0.172 NM_032902
PPP1R16A
protein phosphatase 1, regulatory subunit 16A
chr1_+_207925381 0.169 NM_002389
NM_153826
NM_172350
NM_172351
NM_172352
NM_172353
NM_172359
NM_172361
CD46







CD46 molecule, complement regulatory protein







chr19_-_37157718 0.168 NM_153257
ZNF461
zinc finger protein 461
chr10_+_74870209 0.165 NM_015901
NUDT13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr15_+_74753602 0.163 LOC440288
uncharacterized LOC440288
chr8_+_144731829 0.157 NM_014789
ZNF623
zinc finger protein 623
chr7_-_27192201 0.148


chr13_+_33160537 0.148 NM_015032
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr10_+_114136014 0.146 ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_-_38218573 0.141 EPHA10
EPH receptor A10
chr1_+_201617449 0.140 NM_020443
NAV1
neuron navigator 1
chr1_-_241803203 0.140 NM_014322
OPN3
opsin 3
chr19_+_7968762 0.138 MAP2K7
mitogen-activated protein kinase kinase 7
chr10_-_72362513 0.136 NM_001083116
NM_005041
PRF1

perforin 1 (pore forming protein)

chr17_-_2304217 0.136 NM_020310
MNT
MAX binding protein
chr12_-_56583244 0.133 SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr11_+_7506599 0.132 NM_198474
OLFML1
olfactomedin-like 1
chr22_-_32853372 0.131 NM_174932
BPIFC
BPI fold containing family C
chr19_+_7968765 0.131 MAP2K7
mitogen-activated protein kinase kinase 7
chr1_-_236228374 0.127 NID1
nidogen 1
chr15_+_57998853 0.125 NM_001018102
NM_015532
POLR2M

polymerase (RNA) II (DNA directed) polypeptide M

chr8_+_29952921 0.121 NM_001128208
NM_015344
LEPROTL1

leptin receptor overlapping transcript-like 1

chr8_-_97247757 0.121 NM_001199975
NM_006294
UQCRB

ubiquinol-cytochrome c reductase binding protein

chr19_+_49661031 0.120 TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr3_-_125775609 0.119 NM_001008487
SLC41A3
solute carrier family 41, member 3
chr11_-_27681195 0.111 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr4_-_186347037 0.109 NM_018359
UFSP2
UFM1-specific peptidase 2
chr16_+_2961994 0.109 FLYWCH1
FLYWCH-type zinc finger 1
chr3_+_33840093 0.108 PDCD6IP
programmed cell death 6 interacting protein
chr19_-_49540072 0.107 NM_033377
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr14_-_106208695 0.106


chr19_+_7968820 0.105 MAP2K7
mitogen-activated protein kinase kinase 7
chr22_+_22758538 0.103


chr1_+_223889253 0.101 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr1_-_68299047 0.101 NM_018841
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr13_+_49794471 0.099 NM_001507
MLNR
motilin receptor
chrX_+_66766350 0.098 AR
androgen receptor
chr11_-_63993340 0.097 NM_001160393
TRPT1
tRNA phosphotransferase 1
chr7_-_99527242 0.096 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr5_-_43483937 0.095 NM_022483
C5orf28
chromosome 5 open reading frame 28
chr22_-_23484208 0.094 NM_014433
RTDR1
rhabdoid tumor deletion region gene 1
chr12_+_6937570 0.093 NM_014262
LEPREL2
leprecan-like 2
chr14_+_100531745 0.093 NM_016337
EVL
Enah/Vasp-like
chr9_-_130616760 0.092 ENG
endoglin
chr5_-_180076616 0.091 NM_002020
NM_182925
FLT4

fms-related tyrosine kinase 4

chr22_-_29977325 0.091 NM_003634
NIPSNAP1
nipsnap homolog 1 (C. elegans)
chr1_+_207925409 0.091 CD46
CD46 molecule, complement regulatory protein
chr7_-_10979752 0.089 NM_002489
NDUFA4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr17_-_42019801 0.088 NM_002722
PPY
pancreatic polypeptide
chr7_-_10979683 0.088 NDUFA4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr17_+_5031686 0.087 NM_004505
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr6_+_97010423 0.086 NM_001170807
NM_020482
FHL5

four and a half LIM domains 5

chr11_-_74022609 0.086 NM_182904
P4HA3
prolyl 4-hydroxylase, alpha polypeptide III
chr20_-_34195409 0.086 FER1L4
fer-1-like 4 (C. elegans) pseudogene
chr9_-_130616592 0.084 ENG
endoglin
chr22_+_27017927 0.083 NM_001886
CRYBA4
crystallin, beta A4
chr7_-_128543379 0.083 KCP
kielin/chordin-like protein
chr3_+_33840077 0.083 PDCD6IP
programmed cell death 6 interacting protein
chr6_+_6588933 0.083 NM_004271
LY86
lymphocyte antigen 86
chrX_-_107019001 0.082 NM_198057
TSC22D3
TSC22 domain family, member 3
chr17_+_48172508 0.081 NM_001199900
NM_002611
NM_001199899
PDK2


pyruvate dehydrogenase kinase, isozyme 2


chr15_+_44580870 0.078 NM_138423
NM_177974
CASC4

cancer susceptibility candidate 4

chr8_-_53626982 0.078 RB1CC1
RB1-inducible coiled-coil 1
chr4_+_41992492 0.078 NM_006345
SLC30A9
solute carrier family 30 (zinc transporter), member 9
chr11_-_64901943 0.077 SYVN1
synovial apoptosis inhibitor 1, synoviolin
chr9_-_138591318 0.077 NM_001012415
NM_001101677
SOHLH1

spermatogenesis and oogenesis specific basic helix-loop-helix 1

chr9_-_136150604 0.077 ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr5_-_179050675 0.076 NM_005520
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr5_+_156696351 0.074 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr8_-_132052834 0.072 NM_001115
ADCY8
adenylate cyclase 8 (brain)
chr1_+_180601164 0.072 XPR1
xenotropic and polytropic retrovirus receptor 1
chr1_-_151762905 0.070 NM_001083963
NM_001083964
NM_001083965
NM_006862
TDRKH



tudor and KH domain containing



chr19_+_18747827 0.069 NM_018316
KLHL26
kelch-like 26 (Drosophila)
chr3_+_33840123 0.068 PDCD6IP
programmed cell death 6 interacting protein
chr19_+_56152281 0.066 NM_207115
ZNF580
zinc finger protein 580
chr14_-_106714594 0.066


chr15_+_44580954 0.066 CASC4
cancer susceptibility candidate 4
chr16_-_28518131 0.065 NM_145659
IL27
interleukin 27
chr11_+_2924504 0.065 SLC22A18
solute carrier family 22, member 18
chr1_-_32687939 0.065 TMEM234
transmembrane protein 234
chr1_+_217804665 0.065 NM_138796
SPATA17
spermatogenesis associated 17
chr19_-_22018940 0.064 NM_003423
ZNF43
zinc finger protein 43
chr19_-_47975244 0.064 NM_015063
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr15_+_57998920 0.060 POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr2_+_119981389 0.060 STEAP3
STEAP family member 3, metalloreductase
chr17_-_38074842 0.060 NM_001042471
NM_001165958
NM_001165959
GSDMB


gasdermin B


chr2_-_203103214 0.060 NM_001005781
NM_001005782
NM_003352
SUMO1


SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)


chr17_-_27044728 0.059 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr12_+_120907599 0.058 NM_001037494
DYNLL1
dynein, light chain, LC8-type 1
chr15_-_74658498 0.057 NM_001099773
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr5_-_1494872 0.056 LPCAT1
lysophosphatidylcholine acyltransferase 1
chr6_-_117086812 0.056 NM_001085480
FAM162B
family with sequence similarity 162, member B
chr11_-_119217365 0.055 NM_015645
NM_031433
C1QTNF5
MFRP
C1q and tumor necrosis factor related protein 5
membrane frizzled-related protein
chr2_+_71693817 0.055 NM_001130455
NM_001130982
NM_001130983
NM_001130984
NM_001130985
NM_001130986
NM_001130987
DYSF






dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)






chr8_-_53626991 0.055 NM_001083617
NM_014781
RB1CC1

RB1-inducible coiled-coil 1

chr11_+_2923487 0.054 NM_002555
SLC22A18
solute carrier family 22, member 18
chrX_-_107018889 0.052 TSC22D3
TSC22 domain family, member 3
chr5_-_179050635 0.052 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr17_+_80709913 0.052 NM_005993
TBCD
tubulin folding cofactor D
chr20_-_35374530 0.052 NM_022477
NM_032013
NDRG3

NDRG family member 3

chr1_+_155279514 0.051 FDPS
farnesyl diphosphate synthase
chr19_-_5870546 0.050 NM_002034
FUT5
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr17_+_74075262 0.050 NM_180990
ZACN
zinc activated ligand-gated ion channel
chr19_-_51587466 0.050 NM_022046
KLK14
kallikrein-related peptidase 14
chr12_-_46384365 0.049 NM_004719
SCAF11
SR-related CTD-associated factor 11
chr3_+_179065479 0.049 NM_033540
MFN1
mitofusin 1
chr20_-_35374468 0.048 NDRG3
NDRG family member 3
chr3_+_9958757 0.048 NM_001203263
NM_001203264
NM_001203265
NM_032732
NM_153460
NM_153461
IL17RC





interleukin 17 receptor C





chr8_-_143867931 0.046 NM_003695
LY6D
lymphocyte antigen 6 complex, locus D
chr14_+_105046055 0.046 NM_001008404
C14orf180
chromosome 14 open reading frame 180
chr7_+_139208673 0.045 NM_001080511
CLEC2L
C-type lectin domain family 2, member L
chr1_-_16482426 0.044 NM_004431
EPHA2
EPH receptor A2
chr19_+_40194945 0.044 NM_020129
NM_203471
LGALS14

lectin, galactoside-binding, soluble, 14

chr11_+_14665338 0.043 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr9_+_139981338 0.043 MAN1B1
mannosidase, alpha, class 1B, member 1
chr11_+_14665396 0.043 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr22_+_20008633 0.043 C22orf25
chromosome 22 open reading frame 25
chr1_-_24469571 0.042 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr2_-_197664335 0.042 NM_001206774
NM_012086
GTF3C3

general transcription factor IIIC, polypeptide 3, 102kDa

chr3_+_33840060 0.041 NM_001162429
NM_013374
PDCD6IP

programmed cell death 6 interacting protein

chr9_-_136150629 0.041 NM_020469
ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr22_+_23165273 0.040


chr7_+_128580725 0.040 NM_001098627
IRF5
interferon regulatory factor 5
chr13_-_28024700 0.040 NM_001166263
NM_152912
MTIF3

mitochondrial translational initiation factor 3

chr12_+_123459249 0.039 NM_024623
OGFOD2
2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr11_+_14665308 0.039 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr12_-_112037360 0.038 NM_002973
ATXN2
ataxin 2
chr1_-_94586678 0.038 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr4_+_110481315 0.037 NM_017918
CCDC109B
coiled-coil domain containing 109B
chr2_+_119981383 0.037 NM_001008410
NM_018234
NM_182915
STEAP3


STEAP family member 3, metalloreductase


chr3_-_46505077 0.037 NM_001199149
LTF
lactotransferrin
chr11_+_118257222 0.037 UBE4A
ubiquitination factor E4A
chr9_+_139846767 0.036 NM_178536
LCN12
lipocalin 12
chr18_+_29671817 0.036 NM_016271
RNF138
ring finger protein 138
chr1_-_206288646 0.036 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr11_+_64323089 0.035 NM_018484
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.31 4.78e-03 GO:0016020 membrane
1.31 4.54e-02 GO:0044425 membrane part

Nothing significant found in function category.