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Motif ID: RUNX1..3.p2

Z-value: 1.604

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_131409484	14.116	NM_000758	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr9_-_123688352	12.224		TRAF1	TNF receptor-associated factor 1
chr21_-_36421586	11.202	NM_001754	RUNX1	runt-related transcription factor 1
chr21_-_36421630	10.250		RUNX1	runt-related transcription factor 1
chr1_-_173174611	7.995		TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr5_+_113698304	5.791		KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr1_+_206643786	4.849		IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr2_+_228678556	4.776	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr10_+_91092238	4.684	NM_001031683	IFIT3	interferon-induced protein with tetratricopeptide repeats 3
chr3_-_71179715	4.216		FOXP1	forkhead box P1
chr9_-_123689172	4.196	NM_005658	TRAF1	TNF receptor-associated factor 1
chr3_-_71180061	4.049	NM_001244815	FOXP1	forkhead box P1
chr1_+_206643830	4.044		IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr11_-_128457452	3.829	NM_001143820	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr2_+_103035148	3.706	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr1_-_89488412	3.583	NM_018284	GBP3	guanylate binding protein 3
chr5_+_35856990	3.570	NM_002185	IL7R	interleukin 7 receptor
chr5_+_125695787	3.564	NM_001146319	GRAMD3	GRAM domain containing 3
chr21_-_36421578	3.497		RUNX1	runt-related transcription factor 1
chr12_+_121570630	3.417	NM_002562	P2RX7	purinergic receptor P2X, ligand-gated ion channel, 7
chr1_+_218518675	3.373	NM_001135599 NM_003238	TGFB2	transforming growth factor, beta 2
chrX_+_9431314	3.334	NM_001139466 NM_001139467 NM_001139468	TBL1X	transducin (beta)-like 1X-linked
chr4_-_122137781	3.267	NM_001128843	TNIP3	TNFAIP3 interacting protein 3
chr6_-_31550065	3.096	NM_002341 NM_009588	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr11_+_35198199	2.999		CD44	CD44 molecule (Indian blood group)
chr4_+_89299874	2.923	NM_001165136 NM_017912	HERC6	hect domain and RLD 6
chr13_+_50070527	2.868	NM_001040444	PHF11	PHD finger protein 11
chr1_+_206643585	2.845	NM_001193321 NM_001193322 NM_014002	IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr20_-_62199106	2.788	NM_033405	PRIC285	peroxisomal proliferator-activated receptor A interacting complex 285
chr21_+_43619798	2.746	NM_207627 NM_207628	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr10_+_104154228	2.674	NM_001077493 NM_001077494	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr6_-_11382501	2.535	NM_001142393	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr2_+_74756531	2.516	NM_013247 NM_145074	HTRA2	HtrA serine peptidase 2
chr3_-_189840225	2.470	NM_001134418	LEPREL1	leprecan-like 1
chr3_-_71294229	2.406	NM_001244814	FOXP1	forkhead box P1
chr6_+_45296053	2.387	NM_001015051 NM_001024630	RUNX2	runt-related transcription factor 2
chr6_-_134498973	2.376	NM_001143677	SGK1	serum/glucocorticoid regulated kinase 1
chr12_+_124773709	2.308	NM_181709	FAM101A	family with sequence similarity 101, member A
chr11_-_5345530	2.237	NM_033180	OR51B2	olfactory receptor, family 51, subfamily B, member 2
chr12_+_15125955	2.229	NM_006205	PDE6H	phosphodiesterase 6H, cGMP-specific, cone, gamma
chr3_-_150920946	2.222	NM_013308	GPR171	G protein-coupled receptor 171
chr1_-_150738255	2.213		CTSS	cathepsin S
chr8_-_119964059	2.164	NM_002546	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b
chr11_+_71710971	2.145	NM_001145055	IL18BP	interleukin 18 binding protein
chr11_-_118781612	2.130	NM_182557	BCL9L	B-cell CLL/lymphoma 9-like
chr12_+_78225068	2.124	NM_014903	NAV3	neuron navigator 3
chr17_+_46185125	2.058		SNX11	sorting nexin 11
chr17_+_56232493	2.003	NM_012374	OR4D1	olfactory receptor, family 4, subfamily D, member 1
chr22_+_21996572	1.919		SDF2L1	stromal cell-derived factor 2-like 1
chr22_+_21996591	1.915		SDF2L1	stromal cell-derived factor 2-like 1
chr4_+_89299980	1.877		HERC6	hect domain and RLD 6
chr4_-_76928601	1.873	NM_002416	CXCL9	chemokine (C-X-C motif) ligand 9
chr11_-_57195052	1.857	NM_017611	SLC43A3	solute carrier family 43, member 3
chr6_+_126240369	1.854	NM_001199622	NCOA7	nuclear receptor coactivator 7
chr1_-_150738292	1.849	NM_001199739 NM_004079	CTSS	cathepsin S
chr22_+_21996541	1.831	NM_022044	SDF2L1	stromal cell-derived factor 2-like 1
chr15_-_55563091	1.815	NM_183236	RAB27A	RAB27A, member RAS oncogene family
chr6_+_31543340	1.812	NM_000594	TNF	tumor necrosis factor
chrX_-_83757398	1.783	NM_001177478 NM_001177479 NM_144657	HDX	highly divergent homeobox
chr17_-_1090562	1.773	NM_001159746	ABR	active BCR-related gene
chr2_+_74757116	1.745		HTRA2	HtrA serine peptidase 2
chr22_+_21996615	1.741		SDF2L1	stromal cell-derived factor 2-like 1
chr14_-_91720166	1.738	NM_003485	GPR68	G protein-coupled receptor 68
chr17_+_32582295	1.737	NM_002982	CCL2	chemokine (C-C motif) ligand 2
chr7_+_28448970	1.730		LOC401317	uncharacterized LOC401317
chr14_-_91710851	1.708	NM_001177676	GPR68	G protein-coupled receptor 68
chr18_+_72167021	1.690		CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)
chr11_+_71710662	1.671	NM_001145057	IL18BP	interleukin 18 binding protein
chr2_+_102953716	1.661	NM_003856	IL1RL1	interleukin 1 receptor-like 1
chr15_+_85666291	1.647		PDE8A	phosphodiesterase 8A
chr5_-_140895407	1.643		DIAPH1	diaphanous homolog 1 (Drosophila)
chr6_-_10419786	1.630	NM_001042425	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr13_+_97928196	1.589		MBNL2	muscleblind-like 2 (Drosophila)
chr17_+_25958257	1.578		LGALS9	lectin, galactoside-binding, soluble, 9
chr3_-_71179736	1.575		FOXP1	forkhead box P1
chr2_+_74757127	1.566		HTRA2	HtrA serine peptidase 2
chr17_-_74722614	1.556		JMJD6	jumonji domain containing 6
chr11_+_20070609	1.556		NAV2	neuron navigator 2
chr19_-_50868877	1.546	NM_004851	NAPSA	napsin A aspartic peptidase
chr2_+_74757243	1.538		HTRA2	HtrA serine peptidase 2
chr9_+_115913266	1.520		SLC31A2	solute carrier family 31 (copper transporters), member 2
chr1_+_113236679	1.517		MOV10	Mov10, Moloney leukemia virus 10, homolog (mouse)
chr2_+_127413739	1.498		GYPC	glycophorin C (Gerbich blood group)
chr10_+_114154522	1.479		ACSL5	acyl-CoA synthetase long-chain family member 5
chr2_+_74756986	1.477		HTRA2	HtrA serine peptidase 2
chr19_-_2151332	1.474		AP3D1	adaptor-related protein complex 3, delta 1 subunit
chr9_+_115913227	1.473	NM_001860	SLC31A2	solute carrier family 31 (copper transporters), member 2
chr4_+_89300110	1.464		HERC6	hect domain and RLD 6
chr19_-_49658645	1.448	NM_002152	HRC	histidine rich calcium binding protein
chr12_-_105322056	1.447	NM_032148	SLC41A2	solute carrier family 41, member 2
chr12_-_323255	1.405	NM_001122848 NM_001206931	SLC6A12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr15_+_66694216	1.400		MAP2K1	mitogen-activated protein kinase kinase 1
chr12_+_9822205	1.397	NM_001197318 NM_013269 NM_001004419 NM_001197317 NM_001197319	CLEC2D	C-type lectin domain family 2, member D
chr13_+_97928414	1.390		MBNL2	muscleblind-like 2 (Drosophila)
chr6_+_36646455	1.384	NM_000389 NM_001220778	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr8_-_134072404	1.377	NM_006748	SLA	Src-like-adaptor
chr6_+_160327972	1.360	NM_002377	MAS1	MAS1 oncogene
chr17_-_74722629	1.359		JMJD6	jumonji domain containing 6
chr1_+_172628157	1.347	NM_000639	FASLG	Fas ligand (TNF superfamily, member 6)
chr18_+_21572736	1.347	NM_153211	TTC39C	tetratricopeptide repeat domain 39C
chr7_+_28725597	1.345	NM_001011666	CREB5	cAMP responsive element binding protein 5
chr2_+_74757158	1.323		HTRA2	HtrA serine peptidase 2
chr3_+_29322802	1.309	NM_001003792 NM_001003793 NM_001177711 NM_001177712 NM_014483	RBMS3	RNA binding motif, single stranded interacting protein 3
chr6_-_32163299	1.302	NM_022107	GPSM3	G-protein signaling modulator 3
chr15_+_75494235	1.299		C15orf39	chromosome 15 open reading frame 39
chr15_+_75494196	1.295	NM_015492	C15orf39	chromosome 15 open reading frame 39
chr21_-_36421461	1.285		RUNX1	runt-related transcription factor 1
chr9_-_139292888	1.277	NM_003086	SNAPC4	small nuclear RNA activating complex, polypeptide 4, 190kDa
chr7_+_43152196	1.270	NM_015052	HECW1	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr11_-_2950593	1.267	NM_003311	PHLDA2	pleckstrin homology-like domain, family A, member 2
chr2_+_127413678	1.265	NM_002101 NM_016815	GYPC	glycophorin C (Gerbich blood group)
chr15_+_75494233	1.260		C15orf39	chromosome 15 open reading frame 39
chr10_+_70847817	1.259	NM_002727	SRGN	serglycin
chr17_-_74722666	1.237		JMJD6	jumonji domain containing 6
chr3_-_45267068	1.211		TMEM158	transmembrane protein 158 (gene/pseudogene)
chr4_+_119948554	1.209		SYNPO2	synaptopodin 2
chr5_+_52083685	1.208	NM_181501 NM_015946	ITGA1 PELO	integrin, alpha 1 pelota homolog (Drosophila)
chr12_-_16759430	1.187		LMO3	LIM domain only 3 (rhombotin-like 2)
chr15_-_55562483	1.181	NM_183234 NM_004580	RAB27A	RAB27A, member RAS oncogene family
chr7_+_5632435	1.179	NM_003088	FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr1_-_27732069	1.175		WASF2	WAS protein family, member 2
chr16_+_23847321	1.172		PRKCB	protein kinase C, beta
chr21_-_36260086	1.170		RUNX1	runt-related transcription factor 1
chr15_+_89631625	1.167		ABHD2	abhydrolase domain containing 2
chr1_+_22303417	1.165	NM_007352	CELA3A CELA3B	chymotrypsin-like elastase family, member 3A chymotrypsin-like elastase family, member 3B
chr17_-_74722843	1.160	NM_001081461 NM_015167	JMJD6	jumonji domain containing 6
chr7_+_30634180	1.160	NM_002047	GARS	glycyl-tRNA synthetase
chr2_+_201980929	1.159		CFLAR	CASP8 and FADD-like apoptosis regulator
chr17_-_79919056	1.159	NM_178493	NOTUM	notum pectinacetylesterase homolog (Drosophila)
chr15_+_73976621	1.158	NM_001024736 NM_025240	CD276	CD276 molecule
chr20_-_23967431	1.152	NM_178312	GGTLC1	gamma-glutamyltransferase light chain 1
chr12_-_16759531	1.147	NM_018640	LMO3	LIM domain only 3 (rhombotin-like 2)
chr4_+_71091787	1.135	NM_152997	C4orf7	chromosome 4 open reading frame 7
chr7_+_28338939	1.133	NM_182899	CREB5	cAMP responsive element binding protein 5
chr1_-_150738232	1.127		CTSS	cathepsin S
chr10_+_70847857	1.125		SRGN	serglycin
chr22_-_43411156	1.113	NM_001184970	PACSIN2	protein kinase C and casein kinase substrate in neurons 2
chr16_+_29674564	1.111		SPN	sialophorin
chr17_-_56032494	1.095		CUEDC1	CUE domain containing 1
chr10_+_96522457	1.095	NM_000769	CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19
chr7_+_5632453	1.092		FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr12_+_54410893	1.083		HOXC5 HOXC6	homeobox C5 homeobox C6
chr22_-_43411129	1.081		PACSIN2	protein kinase C and casein kinase substrate in neurons 2
chr19_-_2151534	1.077		AP3D1	adaptor-related protein complex 3, delta 1 subunit
chr15_+_100173182	1.073	NM_001130928	MEF2A	myocyte enhancer factor 2A
chr22_-_30642683	1.066	NM_002309	LIF	leukemia inhibitory factor (cholinergic differentiation factor)
chr5_-_94417185	1.063		MCTP1	multiple C2 domains, transmembrane 1
chr17_+_19281726	1.060	NM_002749 NM_139034	MAPK7	mitogen-activated protein kinase 7
chr19_+_8117645	1.049	NM_001201359 NM_005624	CCL25	chemokine (C-C motif) ligand 25
chr2_-_64881040	1.049	NM_014755	SERTAD2	SERTA domain containing 2
chr1_-_247921707	1.044	NM_012353	OR1C1	olfactory receptor, family 1, subfamily C, member 1
chr9_+_109686436	1.040		ZNF462	zinc finger protein 462
chr7_-_47622127	1.026		TNS3	tensin 3
chr15_-_50647275	1.016		GABPB1	GA binding protein transcription factor, beta subunit 1
chr1_-_33336289	1.015	NM_001171940 NM_153756	FNDC5	fibronectin type III domain containing 5
chr4_+_88896868	1.013		SPP1	secreted phosphoprotein 1
chr4_+_88896838	1.011		SPP1	secreted phosphoprotein 1
chr3_-_71592707	1.009	NM_001244816	FOXP1	forkhead box P1
chr11_+_93862143	1.006		PANX1	pannexin 1
chr5_+_76114832	1.002	NM_005242	F2RL1	coagulation factor II (thrombin) receptor-like 1
chr10_+_101419169	0.994	NM_020354	ENTPD7	ectonucleoside triphosphate diphosphohydrolase 7
chr14_+_96671015	0.979	NM_000623	BDKRB2	bradykinin receptor B2
chr17_-_7493389	0.973	NM_006942	SOX15	SRY (sex determining region Y)-box 15
chr8_+_123794043	0.971		ZHX2	zinc fingers and homeoboxes 2
chr19_-_2151551	0.966	NM_001077523 NM_003938	AP3D1	adaptor-related protein complex 3, delta 1 subunit
chr9_-_136857285	0.949	NM_001134398 NM_003371	VAV2	vav 2 guanine nucleotide exchange factor
chr5_-_137878901	0.933		ETF1	eukaryotic translation termination factor 1
chr6_+_31514627	0.930	NM_001144962 NM_001144963	NFKBIL1	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr5_+_34687663	0.927	NM_001145523	RAI14	retinoic acid induced 14
chr6_+_31539875	0.926	NM_001159740	LTA	lymphotoxin alpha (TNF superfamily, member 1)
chr5_-_137878808	0.921		ETF1	eukaryotic translation termination factor 1
chr4_+_88896899	0.920		SPP1	secreted phosphoprotein 1
chr9_-_32526164	0.916	NM_014314	DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr17_+_19281013	0.915	NM_139032 NM_139033	MAPK7	mitogen-activated protein kinase 7
chrX_-_119005575	0.913	NM_006978	RNF113A	ring finger protein 113A
chr6_-_13295817	0.911	NM_001242698	LOC100130357	uncharacterized LOC100130357
chr5_-_59783885	0.909	NM_001165899	PDE4D	phosphodiesterase 4D, cAMP-specific
chr6_+_14117857	0.904	NM_001040280 NM_004233	CD83	CD83 molecule
chr5_-_137878915	0.903	NM_004730	ETF1	eukaryotic translation termination factor 1
chr9_-_15250113	0.901	NM_001168342	TTC39B	tetratricopeptide repeat domain 39B
chr10_+_13142055	0.895	NM_001008211 NM_001008212 NM_001008213 NM_021980	OPTN	optineurin
chr12_-_4754275	0.892	NM_006422	AKAP3	A kinase (PRKA) anchor protein 3
chr16_-_28608367	0.889	NM_001054	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr1_-_114414245	0.884	NM_001193431 NM_012411 NM_015967	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr19_+_3708358	0.882		TJP3	tight junction protein 3 (zona occludens 3)
chr11_-_10673832	0.880	NM_001098579	MRVI1	murine retrovirus integration site 1 homolog
chr4_+_88896801	0.874	NM_000582 NM_001040058 NM_001040060 NM_001251829 NM_001251830	SPP1	secreted phosphoprotein 1
chr15_+_73976689	0.866		CD276	CD276 molecule
chr5_+_147258273	0.866	NM_054023	SCGB3A2	secretoglobin, family 3A, member 2
chr2_-_214015053	0.862	NM_016260	IKZF2	IKAROS family zinc finger 2 (Helios)
chr6_+_36644236	0.862	NM_001220777 NM_078467	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr5_-_142065586	0.855	NM_000800	FGF1	fibroblast growth factor 1 (acidic)
chr17_+_25958192	0.851		LGALS9	lectin, galactoside-binding, soluble, 9
chr2_+_202671197	0.844	NM_139158	CDK15	cyclin-dependent kinase 15
chr17_-_74722517	0.838		JMJD6	jumonji domain containing 6
chr2_+_171784947	0.837	NM_001201428 NM_015530	GORASP2	golgi reassembly stacking protein 2, 55kDa
chr9_-_86584079	0.833		HNRNPK	heterogeneous nuclear ribonucleoprotein K
chr15_-_43910959	0.832	NM_153700	STRC	stereocilin
chr6_-_68598987	0.832		ERVH-3	endogenous retrovirus group H, member 3
chr4_+_39063851	0.831	NM_015990 NM_199039	KLHL5	kelch-like 5 (Drosophila)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.83	4.46e-12	GO:0002376	immune system process
1.92	3.96e-08	GO:0006955	immune response
1.24	9.25e-08	GO:0050896	response to stimulus
2.12	1.43e-07	GO:0001775	cell activation
1.72	7.66e-06	GO:0009611	response to wounding
1.31	9.14e-06	GO:0023052	signaling
1.31	7.36e-05	GO:0007165	signal transduction
1.68	2.88e-04	GO:0048584	positive regulation of response to stimulus
1.42	5.69e-04	GO:0007166	cell surface receptor linked signaling pathway
2.42	8.15e-04	GO:0046649	lymphocyte activation
1.70	1.15e-03	GO:0002682	regulation of immune system process
1.24	1.36e-03	GO:0051716	cellular response to stimulus
1.82	1.60e-03	GO:0006935	chemotaxis
1.82	1.60e-03	GO:0042330	taxis
1.49	1.74e-03	GO:0051239	regulation of multicellular organismal process
1.87	1.94e-03	GO:0051094	positive regulation of developmental process
2.20	2.13e-03	GO:0045321	leukocyte activation
1.55	2.18e-03	GO:0007154	cell communication
1.59	3.37e-03	GO:0040011	locomotion
1.20	4.73e-03	GO:0032501	multicellular organismal process
2.69	8.12e-03	GO:0042110	T cell activation
1.77	8.65e-03	GO:0000904	cell morphogenesis involved in differentiation
1.52	1.13e-02	GO:0009605	response to external stimulus
1.60	1.29e-02	GO:0007267	cell-cell signaling
1.36	1.36e-02	GO:0048583	regulation of response to stimulus
1.66	1.47e-02	GO:0032989	cellular component morphogenesis
1.79	1.58e-02	GO:0002684	positive regulation of immune system process
1.31	1.82e-02	GO:0048519	negative regulation of biological process
1.28	2.18e-02	GO:0048518	positive regulation of biological process
1.73	2.30e-02	GO:0009967	positive regulation of signal transduction
1.66	2.43e-02	GO:0000902	cell morphogenesis
1.99	3.08e-02	GO:0048534	hemopoietic or lymphoid organ development
1.77	3.11e-02	GO:0048667	cell morphogenesis involved in neuron differentiation
1.98	3.77e-02	GO:0001817	regulation of cytokine production
1.77	4.12e-02	GO:0007409	axonogenesis
1.29	4.68e-02	GO:0006950	response to stress

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.58	1.55e-06	GO:0031226	intrinsic to plasma membrane
1.56	6.97e-06	GO:0005887	integral to plasma membrane
1.39	1.22e-05	GO:0044459	plasma membrane part
1.25	2.41e-05	GO:0071944	cell periphery
1.25	3.22e-05	GO:0005886	plasma membrane
2.39	5.24e-03	GO:0009897	external side of plasma membrane
1.74	1.87e-02	GO:0009986	cell surface
1.49	2.82e-02	GO:0005615	extracellular space

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.23	5.19e-03	GO:0005126	cytokine receptor binding