Motif ID: STAT1,3.p3

Z-value: 0.936


Transcription factors associated with STAT1,3.p3:

Gene SymbolEntrez IDGene Name
STAT1 6772 signal transducer and activator of transcription 1, 91kDa
STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
STAT1chr2_-_191878882-0.893.6e-09Click!
STAT3chr17_-_405403590.491.3e-02Click!


Activity profile for motif STAT1,3.p3.

activity profile for motif STAT1,3.p3


Sorted Z-values histogram for motif STAT1,3.p3

Sorted Z-values for motif STAT1,3.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT1,3.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_76957139 7.620 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr3_+_122399665 7.199 NM_017554
PARP14
poly (ADP-ribose) polymerase family, member 14
chr1_-_153521717 5.852 NM_002960
S100A3
S100 calcium binding protein A3
chr19_+_10381763 5.239 ICAM1
intercellular adhesion molecule 1
chr22_+_36044412 2.539 NM_030641
APOL6
apolipoprotein L, 6
chrX_-_154563735 2.517 NM_001289
CLIC2
chloride intracellular channel 2
chr4_-_122148620 2.512 NM_001244764
TNIP3
TNFAIP3 interacting protein 3
chr12_+_102271082 2.223 NM_018370
DRAM1
DNA-damage regulated autophagy modulator 1
chr10_+_90751044 2.166 FAS
Fas (TNF receptor superfamily, member 6)
chr10_-_90750955 2.143 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr8_+_86158004 2.005 CA13
carbonic anhydrase XIII
chr8_+_86157693 1.988 NM_198584
CA13
carbonic anhydrase XIII
chr11_-_102668822 1.904 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr22_-_31503484 1.876 NM_080430
SELM
selenoprotein M
chr22_+_20861875 1.820 MED15
mediator complex subunit 15
chr5_+_149887673 1.750 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr22_+_20861884 1.738 NM_001003891
NM_015889
MED15

mediator complex subunit 15

chr22_+_20861886 1.733 MED15
mediator complex subunit 15
chr10_+_91152321 1.629 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr22_+_20861898 1.562 MED15
mediator complex subunit 15
chr6_+_36646455 1.372 NM_000389
NM_001220778
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr1_-_144994943 1.275 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr19_+_10381516 1.239 NM_000201
ICAM1
intercellular adhesion molecule 1
chr1_-_144994839 1.222 PDE4DIP
phosphodiesterase 4D interacting protein
chr11_+_62623466 1.122 NM_001012662
NM_001012664
NM_002394
SLC3A2


solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2


chr13_-_95248482 1.085 NM_014305
TGDS
TDP-glucose 4,6-dehydratase
chr20_+_61436160 1.025 NM_007346
OGFR
opioid growth factor receptor
chr9_+_137004913 1.017 NM_052821
WDR5
WD repeat domain 5
chr11_-_102668892 0.977 NM_001145938
NM_002421
MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr7_-_108096693 0.954 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr3_-_119582422 0.944 GSK3B
glycogen synthase kinase 3 beta
chr1_+_156084579 0.792 LMNA
lamin A/C
chr19_+_3762671 0.782 MRPL54
mitochondrial ribosomal protein L54
chr5_+_31799030 0.762 NM_178140
PDZD2
PDZ domain containing 2
chr11_-_615920 0.759 IRF7
interferon regulatory factor 7
chr9_+_132897342 0.744 GPR107
G protein-coupled receptor 107
chr22_-_31536339 0.719 NM_015715
PLA2G3
phospholipase A2, group III
chr9_-_86571631 0.718 C9orf64
chromosome 9 open reading frame 64
chr1_-_144994908 0.697 PDE4DIP
phosphodiesterase 4D interacting protein
chr12_+_56211862 0.692 ORMDL2
ORM1-like 2 (S. cerevisiae)
chr17_+_60457913 0.663 NM_173503
EFCAB3
EF-hand calcium binding domain 3
chr6_+_36646489 0.655 CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr5_-_133706717 0.630 CDKL3
cyclin-dependent kinase-like 3
chr19_+_57106622 0.623 NM_021216
ZNF71
zinc finger protein 71
chr12_+_56211718 0.622 NM_014182
ORMDL2
ORM1-like 2 (S. cerevisiae)
chr13_-_95248401 0.620 TGDS
TDP-glucose 4,6-dehydratase
chr10_-_63212924 0.609 TMEM26
transmembrane protein 26
chr2_+_103035148 0.603 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr16_+_67261010 0.595 NM_014187
TMEM208
transmembrane protein 208
chr12_-_10151689 0.585 NM_001099431
NM_016509
CLEC1B

C-type lectin domain family 1, member B

chr9_-_134585107 0.576 NM_198679
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr5_+_175875372 0.574 FAF2
Fas associated factor family member 2
chr19_+_3762650 0.553 NM_172251
MRPL54
mitochondrial ribosomal protein L54
chr17_-_76183074 0.553 NM_003258
TK1
thymidine kinase 1, soluble
chr5_+_133706869 0.546 NM_003337
UBE2B
ubiquitin-conjugating enzyme E2B
chr9_+_88556102 0.525 NAA35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr11_-_62623212 0.512 SNHG1
small nucleolar RNA host gene 1 (non-protein coding)
chr8_+_25316714 0.506 CDCA2
cell division cycle associated 2
chr1_-_52499432 0.490 NM_138417
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr9_+_88556056 0.488 NM_024635
NAA35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr16_-_3767449 0.482 NM_016292
TRAP1
TNF receptor-associated protein 1
chr6_-_35480635 0.480 NM_003322
TULP1
tubby like protein 1
chr16_+_57653649 0.459 GPR56
G protein-coupled receptor 56
chr5_+_145826866 0.448 NM_001040006
NM_006706
TCERG1

transcription elongation regulator 1

chr2_-_113594325 0.447 NM_000576
IL1B
interleukin 1, beta
chr19_-_6737603 0.444 NM_001080452
GPR108
G protein-coupled receptor 108
chr13_+_99058147 0.437


chr10_+_72575724 0.437 SGPL1
sphingosine-1-phosphate lyase 1
chr11_-_615998 0.422 NM_001572
NM_004029
IRF7

interferon regulatory factor 7

chr11_-_117695408 0.409 NM_001680
FXYD2
FXYD domain containing ion transport regulator 2
chr19_-_38720312 0.406 NM_001135156
DPF1
D4, zinc and double PHD fingers family 1
chr19_+_44331443 0.403 NM_181845
ZNF283
zinc finger protein 283
chr2_-_46384 0.393 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr8_-_104427373 0.392 NM_030780
SLC25A32
solute carrier family 25, member 32
chr4_-_683107 0.383 MFSD7
major facilitator superfamily domain containing 7
chr20_-_43280359 0.383 NM_000022
ADA
adenosine deaminase
chr19_+_48867650 0.379 NM_012451
SYNGR4
synaptogyrin 4
chr19_+_44488331 0.378 NM_003445
NM_198089
ZNF155

zinc finger protein 155

chrX_+_102862833 0.377 NM_001006933
NM_032926
TCEAL3

transcription elongation factor A (SII)-like 3

chr8_-_27168783 0.367 NM_171982
TRIM35
tripartite motif containing 35
chr3_+_115342150 0.362 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr11_-_118966175 0.360 NM_002105
H2AFX
H2A histone family, member X
chr11_-_615649 0.354 NM_004031
IRF7
interferon regulatory factor 7
chr1_-_161519817 0.353 NM_000569
NM_001127592
FCGR3A

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

chr22_+_20861964 0.350 MED15
mediator complex subunit 15
chr5_+_175875386 0.349 FAF2
Fas associated factor family member 2
chr14_-_36982976 0.348 NM_001101341
SFTA3
surfactant associated 3
chr8_+_25316736 0.346 CDCA2
cell division cycle associated 2
chr13_+_25946084 0.339 NM_016529
ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr8_-_143859177 0.330 LYNX1
Ly6/neurotoxin 1
chr12_-_122231554 0.330 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chr10_-_75415748 0.330 NM_001114133
SYNPO2L
synaptopodin 2-like
chr4_-_185395616 0.330 NM_002199
IRF2
interferon regulatory factor 2
chr1_-_16539103 0.329 NM_153213
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr9_+_130186714 0.327 ZNF79
zinc finger protein 79
chr11_-_64703334 0.324 NM_130769
GPHA2
glycoprotein hormone alpha 2
chr7_-_149157866 0.316 NM_015694
ZNF777
zinc finger protein 777
chr1_-_42630386 0.307 NM_033553
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr7_-_44613488 0.304 DDX56
DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
chr19_-_15590203 0.290 NM_052890
PGLYRP2
peptidoglycan recognition protein 2
chr19_-_893215 0.289 NM_005481
MED16
mediator complex subunit 16
chr19_-_40331153 0.284 FBL
fibrillarin
chr16_-_1470709 0.282 C16orf91
chromosome 16 open reading frame 91
chr11_+_32112414 0.281 NM_002901
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr20_+_37101457 0.280 NM_020336
RALGAPB
Ral GTPase activating protein, beta subunit (non-catalytic)
chr6_+_31913852 0.276 CFB
complement factor B
chr5_+_175875355 0.274 NM_014613
FAF2
Fas associated factor family member 2
chr9_+_136287119 0.269 NM_139025
NM_139026
NM_139027
ADAMTS13


ADAM metallopeptidase with thrombospondin type 1 motif, 13


chr6_+_36644236 0.267 NM_001220777
NM_078467
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr1_-_161519526 0.263 FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr16_+_4674829 0.262 MGRN1
mahogunin, ring finger 1
chr6_-_25874439 0.255 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr17_+_32646058 0.253 NM_005623
CCL8
chemokine (C-C motif) ligand 8
chr3_+_128598520 0.252 ACAD9
acyl-CoA dehydrogenase family, member 9
chr3_-_118959723 0.249 NM_003778
NM_212543
B4GALT4

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4

chr8_-_134115309 0.247 NM_001045556
NM_001045557
SLA

Src-like-adaptor

chr19_-_6737565 0.241 GPR108
G protein-coupled receptor 108
chr2_+_171785780 0.241 GORASP2
golgi reassembly stacking protein 2, 55kDa
chr19_+_44716683 0.240 NM_182490
ZNF227
zinc finger protein 227
chr6_+_41303527 0.240 NM_001199509
NM_001199510
NM_004828
NCR2


natural cytotoxicity triggering receptor 2


chr18_-_52626636 0.240 NM_025214
CCDC68
coiled-coil domain containing 68
chr4_+_119809978 0.233 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr20_+_35973083 0.230 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr16_+_70207927 0.229 NM_173619
CLEC18C
CLEC18A
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
chr22_+_18121540 0.223 BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr2_-_11810254 0.222 NM_012344
NTSR2
neurotensin receptor 2
chr14_+_55168831 0.222 SAMD4A
sterile alpha motif domain containing 4A
chr8_-_18666295 0.222 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr16_-_74455239 0.215 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr18_+_55714457 0.215 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr10_+_86004808 0.212 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr3_+_187086167 0.208 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr9_-_131038196 0.207 NM_004486
GOLGA2
golgin A2
chr2_+_170366211 0.206 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr17_-_6983503 0.205 NM_006344
NM_182906
CLEC10A

C-type lectin domain family 10, member A

chr14_+_73957670 0.204 C14orf169
chromosome 14 open reading frame 169
chr1_+_54519259 0.201 NM_153035
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr19_+_44598479 0.201 NM_013398
ZNF224
zinc finger protein 224
chr3_+_130612806 0.199 NM_001199179
NM_001001485
NM_001199183
NM_001199184
NM_001199185
NM_014382
NM_001001486
NM_001001487
ATP2C1







ATPase, Ca++ transporting, type 2C, member 1







chr11_+_46694514 0.194 ATG13
ATG13 autophagy related 13 homolog (S. cerevisiae)
chr3_+_128598471 0.194 ACAD9
acyl-CoA dehydrogenase family, member 9
chr6_-_111136616 0.194 CDK19
cyclin-dependent kinase 19
chr3_+_115342302 0.192 GAP43
growth associated protein 43
chr3_+_128598440 0.191 ACAD9
acyl-CoA dehydrogenase family, member 9
chr8_+_36641841 0.191 NM_001031836
KCNU1
potassium channel, subfamily U, member 1
chr3_+_128598459 0.191 ACAD9
acyl-CoA dehydrogenase family, member 9
chr9_+_130186652 0.181 NM_007135
ZNF79
zinc finger protein 79
chr19_-_893184 0.180 MED16
mediator complex subunit 16
chr5_+_178368193 0.176 NM_001178089
NM_001178090
NM_182594
ZNF454


zinc finger protein 454


chr20_+_2795613 0.175 NM_080739
C20orf141
chromosome 20 open reading frame 141
chr20_+_24449834 0.174 NM_024893
SYNDIG1
synapse differentiation inducing 1
chr6_+_31540092 0.174 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr11_-_118966103 0.173 H2AFX
H2A histone family, member X
chr19_-_6737589 0.172 GPR108
G protein-coupled receptor 108
chr4_-_48136245 0.169 NM_003328
TXK
TXK tyrosine kinase
chr18_+_268147 0.160


chr4_-_176733901 0.158 GPM6A
glycoprotein M6A
chr1_-_212004113 0.156 NM_014873
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr5_-_138725544 0.154 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr4_+_3443659 0.154 HGFAC
HGF activator
chr14_+_67707825 0.146 NM_022474
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr6_+_54711568 0.146 NM_001010872
FAM83B
family with sequence similarity 83, member B
chr9_-_137809710 0.145 NM_002003
FCN1
ficolin (collagen/fibrinogen domain containing) 1
chr10_+_95848811 0.145 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr16_-_29910340 0.145 NM_001114099
NM_001114100
NM_001243332
NM_001243333
NM_012410
NM_201575
SEZ6L2





seizure related 6 homolog (mouse)-like 2





chr8_-_143859638 0.145 NM_023946
NM_177457
LYNX1

Ly6/neurotoxin 1

chr17_+_7462064 0.145 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr3_+_128598332 0.141 NM_014049
ACAD9
acyl-CoA dehydrogenase family, member 9
chr10_-_61469322 0.140 NM_194298
LOC100129721
SLC16A9
uncharacterized LOC100129721
solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr11_+_61447816 0.140 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr2_+_149894980 0.138 NM_177964
LYPD6B
LY6/PLAUR domain containing 6B
chr4_+_3443691 0.138 NM_001528
HGFAC
HGF activator
chr17_-_3030844 0.136 NM_003555
OR1G1
olfactory receptor, family 1, subfamily G, member 1
chr3_+_37284680 0.135 NM_001172713
NM_002078
GOLGA4

golgin A4

chr17_-_39254374 0.134 NM_031960
KRTAP4-8
keratin associated protein 4-8
chr5_+_140261792 0.131 NM_018904
NM_031865
PCDHA13

protocadherin alpha 13

chr5_+_33441046 0.130 TARS
threonyl-tRNA synthetase
chr20_-_34243118 0.125 RBM12
RNA binding motif protein 12
chr14_-_68141328 0.124 NM_006370
VTI1B
vesicle transport through interaction with t-SNAREs homolog 1B (yeast)
chr11_-_129062092 0.123 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr20_-_6034617 0.120 NM_152611
LRRN4
leucine rich repeat neuronal 4
chr4_-_21546278 0.118 NM_001035004
KCNIP4
Kv channel interacting protein 4
chr1_+_46153846 0.112 NM_016486
TMEM69
transmembrane protein 69
chr9_-_23821477 0.111 NM_001171197
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr10_+_71029755 0.110 NM_033497
NM_033498
NM_033500
HK1


hexokinase 1


chr6_+_31913763 0.109 CFB
complement factor B
chr9_+_74764394 0.109 GDA
guanine deaminase
chr22_-_24096551 0.107 NM_013378
VPREB3
pre-B lymphocyte 3
chr19_+_42300521 0.107 NM_001815
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr6_+_53883713 0.105 NM_138569
MLIP
muscular LMNA-interacting protein
chr12_-_75603214 0.104 KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr19_+_10828813 0.102 DNM2
dynamin 2
chr9_+_74764382 0.100 GDA
guanine deaminase
chr1_+_50569581 0.099 NM_001144776
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr19_+_49977465 0.098 NM_001204502
NM_001459
FLT3LG

fms-related tyrosine kinase 3 ligand

chr1_+_156123321 0.098 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr2_+_30670082 0.098 NM_182551
NM_001002257
LCLAT1

lysocardiolipin acyltransferase 1

chr1_+_34632483 0.092 NM_032884
C1orf94
chromosome 1 open reading frame 94
chr19_-_14049167 0.091 NM_024825
PODNL1
podocan-like 1
chr3_+_128598497 0.090 ACAD9
acyl-CoA dehydrogenase family, member 9

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.