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Motif ID: TBX4,5.p2

Z-value: 1.322

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_-_54421269	2.842	NM_130851	BMP4	bone morphogenetic protein 4
chr8_+_120220554	2.621	NM_052886	MAL2	mal, T-cell differentiation protein 2 (gene/pseudogene)
chr7_+_30951414	2.547	NM_198098	AQP1	aquaporin 1 (Colton blood group)
chr11_-_33913835	2.385	NM_005574	LMO2	LIM domain only 2 (rhombotin-like 1)
chrX_-_117250624	1.940	NM_001168302 NM_001168303	KLHL13	kelch-like 13 (Drosophila)
chr2_-_61697846	1.886	NM_014709	USP34	ubiquitin specific peptidase 34
chr5_-_43313492	1.877		HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr17_+_68165660	1.820	NM_000891	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2
chr3_+_39851028	1.747	NM_015460	MYRIP	myosin VIIA and Rab interacting protein
chr11_-_119234628	1.721		USP2	ubiquitin specific peptidase 2
chr4_+_156587861	1.677	NM_000856 NM_001130682 NM_001130686 NM_001130687 NM_001130683 NM_001130685	GUCY1A3	guanylate cyclase 1, soluble, alpha 3
chr11_-_33891258	1.661		LMO2	LIM domain only 2 (rhombotin-like 1)
chr4_-_99579540	1.661	NM_005723	TSPAN5	tetraspanin 5
chr1_+_100111430	1.606	NM_017734	PALMD	palmdelphin
chr5_-_43313581	1.554	NM_001098272 NM_002130	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr17_+_61562177	1.547	NM_001178057 NM_152830	ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr2_-_61697899	1.546		USP34	ubiquitin specific peptidase 34
chr4_+_156588811	1.501	NM_001130684	GUCY1A3	guanylate cyclase 1, soluble, alpha 3
chr3_-_158390266	1.483	NM_020169	LXN	latexin
chr2_+_61108702	1.482		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr4_+_41361621	1.482		LIMCH1	LIM and calponin homology domains 1
chr9_-_132805256	1.421		FNBP1	formin binding protein 1
chr19_+_38755238	1.417		SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr2_+_61108724	1.389	NM_002908	REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr4_+_156680603	1.376		GUCY1B3	guanylate cyclase 1, soluble, beta 3
chr8_-_22550057	1.354	NM_001199881	EGR3	early growth response 3
chr8_-_80993009	1.324	NM_001025252	TPD52	tumor protein D52
chr10_-_94333721	1.319		IDE	insulin-degrading enzyme
chr2_-_191878908	1.318		STAT1	signal transducer and activator of transcription 1, 91kDa
chr8_+_21912327	1.309	NM_001114136 NM_001114139	EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr11_-_33891485	1.253	NM_001142315	LMO2	LIM domain only 2 (rhombotin-like 1)
chr21_+_38445562	1.253	NM_001001894	TTC3	tetratricopeptide repeat domain 3
chr19_+_38755097	1.242	NM_001166103 NM_021102	SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr1_-_33168356	1.232	NM_001161708 NM_030786	SYNC	syncoilin, intermediate filament protein
chr4_-_186733372	1.229	NM_003603 NM_001145670	SORBS2	sorbin and SH3 domain containing 2
chr5_+_68788118	1.225	NM_002538	OCLN	occludin
chr2_-_191878924	1.225	NM_007315 NM_139266	STAT1	signal transducer and activator of transcription 1, 91kDa
chr1_+_45274153	1.218	NM_001136537	BTBD19	BTB (POZ) domain containing 19
chr10_+_94608224	1.215	NM_019053	EXOC6	exocyst complex component 6
chr5_+_139027955	1.190		CXXC5	CXXC finger protein 5
chr1_+_185703470	1.178	NM_031935	HMCN1	hemicentin 1
chr1_+_65991357	1.177	NM_001198687 NM_001198688 NM_001198689	LEPR	leptin receptor
chr18_+_59992519	1.169	NM_003839	TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr9_-_132805456	1.162	NM_015033	FNBP1	formin binding protein 1
chr4_-_114682836	1.160	NM_001221 NM_172114 NM_172115 NM_172127 NM_172128 NM_172129	CAMK2D	calcium/calmodulin-dependent protein kinase II delta
chr10_-_125853102	1.159		CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr2_-_191878882	1.158		STAT1	signal transducer and activator of transcription 1, 91kDa
chr10_-_94333828	1.132		IDE	insulin-degrading enzyme
chr8_-_22549901	1.112	NM_001199880	EGR3	early growth response 3
chr8_-_93029864	1.105	NM_175636	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_134514044	1.103	NM_004441	EPHB1	EPH receptor B1
chr2_-_190445466	1.096		SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1
chr14_-_100841656	1.072		WARS	tryptophanyl-tRNA synthetase
chr9_-_100459556	1.057		XPA	xeroderma pigmentosum, complementation group A
chrX_-_63005212	1.053	NM_001173479	ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr12_-_96184510	1.049	NM_021229	NTN4	netrin 4
chr6_-_28303910	1.045	NM_001135216 NM_001243243	ZNF323	zinc finger protein 323
chr2_-_190445612	1.042		SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1
chr13_+_49550949	1.032		FNDC3A	fibronectin type III domain containing 3A
chrX_+_135251454	1.025	NM_001159704	FHL1	four and a half LIM domains 1
chr5_-_112824526	1.017	NM_001085377	MCC	mutated in colorectal cancers
chr2_-_190445521	1.016	NM_014585	SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1
chr11_-_124632050	1.011	NM_138961	ESAM	endothelial cell adhesion molecule
chr4_-_159092509	1.005		FAM198B	family with sequence similarity 198, member B
chr19_+_7741934	0.995	NM_174918	C19orf59	chromosome 19 open reading frame 59
chr12_+_7169192	0.982
chr14_-_57735527	0.978		EXOC5	exocyst complex component 5
chr9_+_124048869	0.964		GSN	gelsolin
chr1_+_155100304	0.963	NM_004428 NM_182685	EFNA1	ephrin-A1
chr16_+_69139466	0.958	NM_001199280	HAS3	hyaluronan synthase 3
chr11_+_66824308	0.957		RHOD	ras homolog gene family, member D
chr11_+_64879294	0.946	NM_003273	TM7SF2	transmembrane 7 superfamily member 2
chr2_+_61108775	0.933		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr7_-_74867340	0.908	NM_001145064	GTF2IP1 GATSL2	general transcription factor IIi, pseudogene 1 GATS protein-like 2
chr1_+_65991390	0.905		LEPR	leptin receptor
chr6_+_35995583	0.894		MAPK14	mitogen-activated protein kinase 14
chr12_+_56661026	0.888	NM_001099337	COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr5_+_140571903	0.884	NM_018930	PCDHB10	protocadherin beta 10
chr3_-_197024879	0.879		DLG1	discs, large homolog 1 (Drosophila)
chr4_-_114682594	0.878		CAMK2D	calcium/calmodulin-dependent protein kinase II delta
chr12_-_104443914	0.878	NM_031302	GLT8D2	glycosyltransferase 8 domain containing 2
chr3_+_25469833	0.871	NM_000965	RARB	retinoic acid receptor, beta
chr8_+_70378858	0.862	NM_001128204 NM_015170	SULF1	sulfatase 1
chr18_-_52969714	0.857	NM_001243236	TCF4	transcription factor 4
chr2_+_177053306	0.847	NM_024501	HOXD1	homeobox D1
chr12_-_76424474	0.838		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr5_+_139028483	0.838		CXXC5	CXXC finger protein 5
chr7_+_150434679	0.837		GIMAP5	GTPase, IMAP family member 5
chr19_+_39155209	0.832
chr7_+_150688143	0.831	NM_000603	NOS3	nitric oxide synthase 3 (endothelial cell)
chr1_+_84767288	0.826	NM_001134663	SAMD13	sterile alpha motif domain containing 13
chr5_+_139027907	0.824		CXXC5	CXXC finger protein 5
chr7_+_150434435	0.822	NM_018384	GIMAP5	GTPase, IMAP family member 5
chr4_+_42399855	0.811	NM_001080505	SHISA3	shisa homolog 3 (Xenopus laevis)
chr1_-_94586678	0.808	NM_000350	ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4
chr6_+_35995585	0.807		MAPK14	mitogen-activated protein kinase 14
chr6_-_13295817	0.801	NM_001242698	LOC100130357	uncharacterized LOC100130357
chrX_-_119709618	0.795	NM_003588	CUL4B	cullin 4B
chr3_+_15247743	0.789		CAPN7	calpain 7
chr6_+_84743250	0.781	NM_138409	MRAP2	melanocortin 2 receptor accessory protein 2
chr11_-_46722139	0.778		ARHGAP1	Rho GTPase activating protein 1
chr6_-_35696359	0.775	NM_001145775	FKBP5	FK506 binding protein 5
chr6_+_31623668	0.771	NM_019101	APOM	apolipoprotein M
chr5_-_78282356	0.768	NM_000046	ARSB	arylsulfatase B
chr15_-_73076025	0.755		ADPGK	ADP-dependent glucokinase
chr8_-_124553253	0.750		FBXO32	F-box protein 32
chr16_-_2581358	0.747	NM_001048212	CEMP1	cementum protein 1
chr2_+_219745243	0.744	NM_025216	WNT10A	wingless-type MMTV integration site family, member 10A
chr12_-_9913415	0.740	NM_001781	CD69	CD69 molecule
chr12_+_79258794	0.737		SYT1	synaptotagmin I
chr5_-_177423242	0.722	NM_006261	PROP1	PROP paired-like homeobox 1
chr17_-_57184116	0.718		TRIM37	tripartite motif containing 37
chr5_-_44388666	0.716	NM_004465	FGF10	fibroblast growth factor 10
chr4_+_120133729	0.715
chr17_-_61523544	0.708	NM_001017916 NM_001915	CYB561	cytochrome b-561
chr18_+_11981421	0.707	NM_014214	IMPA2	inositol(myo)-1(or 4)-monophosphatase 2
chr11_+_44785975	0.707	NM_130783	TSPAN18	tetraspanin 18
chr8_-_81083660	0.700	NM_001025253 NM_005079	TPD52	tumor protein D52
chr9_-_75567915	0.694		ALDH1A1	aldehyde dehydrogenase 1 family, member A1
chr7_-_94285372	0.694		SGCE	sarcoglycan, epsilon
chr11_+_66824285	0.689	NM_014578	RHOD	ras homolog gene family, member D
chr6_-_16761600	0.689	NM_000332 NM_001128164	ATXN1	ataxin 1
chr2_-_188419049	0.687		TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr9_+_124048396	0.686		GSN	gelsolin
chrX_+_149531439	0.680	NM_001177465	MAMLD1	mastermind-like domain containing 1
chr10_-_81205091	0.679	NM_153367	ZCCHC24	zinc finger, CCHC domain containing 24
chr4_+_90816002	0.679	NM_007351	MMRN1	multimerin 1
chr22_+_50528307	0.673	NM_001164104 NM_018995	MOV10L1	Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
chr8_-_124553448	0.672	NM_001242463 NM_058229	FBXO32	F-box protein 32
chr3_+_151985828	0.671	NM_021038 NM_207292	MBNL1	muscleblind-like (Drosophila)
chr19_+_38755422	0.667		SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr12_+_104324214	0.666		HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
chr6_-_167571315	0.665	NM_005299	GPR31	G protein-coupled receptor 31
chr4_-_42658883	0.664	NM_001105529 NM_006095	ATP8A1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr12_+_110011499	0.661	NM_000431 NM_001114185	MVK	mevalonate kinase
chr14_-_51135041	0.660		SAV1	salvador homolog 1 (Drosophila)
chr5_+_68788387	0.657	NM_001205254	OCLN	occludin
chr2_+_207139413	0.651	NM_020923	ZDBF2	zinc finger, DBF-type containing 2
chr2_+_170590454	0.649		KLHL23	kelch-like 23 (Drosophila)
chr5_-_148930944	0.649		CSNK1A1	casein kinase 1, alpha 1
chr3_-_187454247	0.644	NM_001130845	BCL6	B-cell CLL/lymphoma 6
chr1_-_161102367	0.643		DEDD	death effector domain containing
chr3_+_134514300	0.641		EPHB1	EPH receptor B1
chr18_+_77659446	0.637
chr12_-_104443698	0.633		GLT8D2	glycosyltransferase 8 domain containing 2
chr14_-_51135021	0.633	NM_021818	SAV1	salvador homolog 1 (Drosophila)
chr22_+_38201113	0.633	NM_005318	H1F0	H1 histone family, member 0
chr9_-_74979829	0.632	NM_001102420 NM_001102421 NM_006007	ZFAND5	zinc finger, AN1-type domain 5
chr15_-_69113213	0.632		ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr15_-_93631751	0.632	NM_001166287	RGMA	RGM domain family, member A
chr20_+_33759773	0.629	NM_006404	PROCR	protein C receptor, endothelial
chr4_+_120133764	0.624	NM_019050	USP53	ubiquitin specific peptidase 53
chr15_+_83776323	0.622	NM_001144903 NM_023003	TM6SF1	transmembrane 6 superfamily member 1
chr2_+_208394823	0.622		CREB1	cAMP responsive element binding protein 1
chr12_+_104324192	0.620		HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
chr6_+_35995513	0.619		MAPK14	mitogen-activated protein kinase 14
chr12_+_52416615	0.610	NM_001202233	NR4A1	nuclear receptor subfamily 4, group A, member 1
chr19_+_48972464	0.610	NM_004228 NM_017457	CYTH2	cytohesin 2
chr1_+_38022514	0.606	NM_003462	DNALI1	dynein, axonemal, light intermediate chain 1
chr7_+_104654494	0.606	NM_018682 NM_182931	MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr7_-_94285426	0.604		SGCE	sarcoglycan, epsilon
chr14_-_51134862	0.594		SAV1	salvador homolog 1 (Drosophila)
chr5_+_139028025	0.593	NM_016463	CXXC5	CXXC finger protein 5
chr9_-_75568232	0.590	NM_000689	ALDH1A1	aldehyde dehydrogenase 1 family, member A1
chr1_-_161102210	0.589	NM_001039712	DEDD	death effector domain containing
chr11_+_63448868	0.588	NM_006054 NM_201428 NM_201429 NM_201430	RTN3	reticulon 3
chr11_-_2170792	0.588	NM_001007139	IGF2	insulin-like growth factor 2 (somatomedin A)
chr12_-_25055228	0.581	NM_001178094	BCAT1	branched chain amino-acid transaminase 1, cytosolic
chr8_+_22436253	0.581	NM_021630	PDLIM2	PDZ and LIM domain 2 (mystique)
chr12_+_104324157	0.579		HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
chr12_+_79257772	0.578	NM_001135805	SYT1	synaptotagmin I
chr20_+_42574535	0.577	NM_001098798	TOX2	TOX high mobility group box family member 2
chr22_+_40441371	0.577		TNRC6B	trinucleotide repeat containing 6B
chr7_+_75508265	0.574	NM_001040456 NM_001040457	RHBDD2	rhomboid domain containing 2
chr20_-_3149070	0.565	NM_014731	ProSAPiP1	ProSAPiP1 protein
chr17_-_27229922	0.565	NM_144683	DHRS13	dehydrogenase/reductase (SDR family) member 13
chr4_+_108745718	0.564	NM_001136258	SGMS2	sphingomyelin synthase 2
chr5_-_179718963	0.564		MAPK9	mitogen-activated protein kinase 9
chr19_+_14491920	0.564	NM_001025160 NM_001784 NM_078481	CD97	CD97 molecule
chr22_-_29075708	0.563	NM_001145418	TTC28	tetratricopeptide repeat domain 28
chr10_+_97515408	0.563	NM_001164178 NM_001164181 NM_001164179 NM_001164182 NM_001164183 NM_001776	ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1
chr17_-_34195745	0.563	NM_152781	C17orf66	chromosome 17 open reading frame 66
chr5_+_153418518	0.563	NM_001135037 NM_001242336 NM_005927	MFAP3	microfibrillar-associated protein 3
chr12_+_51318743	0.562		METTL7A	methyltransferase like 7A
chr1_-_151345156	0.562	NM_003944	SELENBP1	selenium binding protein 1
chr11_+_114310107	0.561	NM_015523	REXO2	REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr11_-_104034685	0.559		PDGFD	platelet derived growth factor D
chr11_+_66384052	0.559	NM_001198845 NM_001198846 NM_001198836 NM_001198837 NM_006328	RBM14-RBM4 RBM14	RBM14-RBM4 readthrough RNA binding motif protein 14
chr7_-_20826503	0.557	NM_182700 NM_198956	SP8	Sp8 transcription factor
chr13_+_49550911	0.557		FNDC3A	fibronectin type III domain containing 3A
chr9_-_74979625	0.555		ZFAND5	zinc finger, AN1-type domain 5
chr1_-_205290756	0.553	NM_030952	NUAK2	NUAK family, SNF1-like kinase, 2
chr1_+_90024271	0.553	NM_015350	LRRC8B	leucine rich repeat containing 8 family, member B
chr7_-_94285477	0.550	NM_001099400 NM_001099401 NM_003919	SGCE	sarcoglycan, epsilon
chr13_+_49550627	0.545		FNDC3A	fibronectin type III domain containing 3A
chr8_-_127570710	0.545	NM_174911	FAM84B	family with sequence similarity 84, member B
chr7_+_114562140	0.545	NM_001166345 NM_001166346 NM_199072	MDFIC	MyoD family inhibitor domain containing
chr7_+_94285736	0.545		PEG10	paternally expressed 10
chr12_-_110011286	0.543	NM_052845	MMAB	methylmalonic aciduria (cobalamin deficiency) cblB type
chr2_-_145090028	0.540		GTDC1	glycosyltransferase-like domain containing 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.07	2.32e-02	GO:0009987	cellular process
1.63	3.23e-02	GO:0032583	regulation of gene-specific transcription
3.33	4.56e-02	GO:0016126	sterol biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.13	4.09e-06	GO:0005737	cytoplasm
2.10	1.63e-05	GO:0016323	basolateral plasma membrane
1.41	9.44e-04	GO:0005783	endoplasmic reticulum
2.39	3.79e-03	GO:0005925	focal adhesion
2.27	1.04e-02	GO:0005924	cell-substrate adherens junction
1.13	1.25e-02	GO:0044444	cytoplasmic part
1.29	1.52e-02	GO:0012505	endomembrane system
1.24	1.58e-02	GO:0044459	plasma membrane part
1.42	2.12e-02	GO:0044432	endoplasmic reticulum part
2.19	2.20e-02	GO:0030055	cell-substrate junction
1.98	2.55e-02	GO:0005912	adherens junction
1.89	4.51e-02	GO:0070161	anchoring junction
1.81	4.75e-02	GO:0005911	cell-cell junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
3.59	8.54e-04	GO:0003823	antigen binding