Motif ID: TEAD1.p2

Z-value: 0.848


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
TEAD1chr11_+_129607930.663.1e-04Click!
TEAD4chr12_+_30689890.592.0e-03Click!
TEAD2chr19_-_498656380.527.3e-03Click!
TEAD3chr6_-_354647160.164.5e-01Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_186733372 4.914 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr10_-_116392099 4.191 ABLIM1
actin binding LIM protein 1
chr5_-_39424930 3.965 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr5_-_39425030 3.437 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr10_-_125853102 3.055 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr1_+_164528586 3.011 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr19_+_34972866 2.587 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr4_-_186578122 2.529 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr1_-_214724844 2.476 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr1_-_92351476 2.476 TGFBR3
transforming growth factor, beta receptor III
chr12_+_53442732 2.350 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr18_+_8717368 2.330 NM_015210
CCDC165
coiled-coil domain containing 165
chr3_-_149051258 2.226 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr20_+_42574535 2.150 NM_001098798
TOX2
TOX high mobility group box family member 2
chr8_+_144816287 2.106 LOC100128338
uncharacterized LOC100128338
chr1_+_61547625 2.072 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr1_-_92351613 1.960 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr4_+_41540320 1.933 LIMCH1
LIM and calponin homology domains 1
chr1_+_32043745 1.836 NM_001204415
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr12_+_79258517 1.712 SYT1
synaptotagmin I
chr12_-_96184510 1.679 NM_021229
NTN4
netrin 4
chr1_-_109935869 1.676 NM_001205228
SORT1
sortilin 1
chr5_-_39425297 1.590 NM_001244871
NM_001343
DAB2

disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

chr12_+_79258588 1.566 SYT1
synaptotagmin I
chr6_-_132272311 1.508 NM_001901
CTGF
connective tissue growth factor
chrX_-_62570968 1.488 NM_001012968
SPIN4
spindlin family, member 4
chr1_+_114522029 1.460 NM_020190
OLFML3
olfactomedin-like 3
chr1_+_78354199 1.353 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr12_+_79258448 1.319 NM_005639
SYT1
synaptotagmin I
chr12_-_56615484 1.314 NM_001242826
RNF41
ring finger protein 41
chr2_+_45878912 1.306 NM_005400
PRKCE
protein kinase C, epsilon
chr4_-_186577858 1.243 SORBS2
sorbin and SH3 domain containing 2
chr11_+_66824285 1.233 NM_014578
RHOD
ras homolog gene family, member D
chr6_+_143999058 1.186 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr11_+_66824308 1.092 RHOD
ras homolog gene family, member D
chr1_+_63833324 1.066 ALG6
asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr8_-_27630096 1.064 NM_018246
CCDC25
coiled-coil domain containing 25
chr12_+_79257772 1.048 NM_001135805
SYT1
synaptotagmin I
chr15_+_39873276 1.042 NM_003246
THBS1
thrombospondin 1
chr6_+_52930160 1.039 FBXO9
F-box protein 9
chr2_-_158731622 1.020 NM_001105
ACVR1
activin A receptor, type I
chr6_-_41909386 1.016 NM_001136125
NM_001760
CCND3

cyclin D3

chr6_-_32191779 1.015 NM_004557
NOTCH4
notch 4
chr17_-_67057046 1.015 NM_080283
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr1_+_63833260 0.985 NM_013339
ALG6
asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr6_+_52930217 0.970 FBXO9
F-box protein 9
chrX_-_10588458 0.961 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr2_-_238499317 0.951 RAB17
RAB17, member RAS oncogene family
chr3_-_112359660 0.918 CCDC80
coiled-coil domain containing 80
chr3_-_112359547 0.910 CCDC80
coiled-coil domain containing 80
chr12_-_12419702 0.908 NM_002336
LRP6
low density lipoprotein receptor-related protein 6
chr3_-_112359251 0.907 CCDC80
coiled-coil domain containing 80
chr11_-_6341708 0.895 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr6_+_123109970 0.894 NM_006714
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr11_-_2170792 0.893 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr17_+_7758380 0.880 NM_203411
TMEM88
transmembrane protein 88
chr2_-_238499713 0.877 NM_022449
RAB17
RAB17, member RAS oncogene family
chr4_-_152149042 0.875 NM_001243349
SH3D19
SH3 domain containing 19
chr3_-_112359443 0.868 CCDC80
coiled-coil domain containing 80
chr18_+_77155927 0.857 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr3_-_112359565 0.844 CCDC80
coiled-coil domain containing 80
chr14_-_21270537 0.820 NM_198232
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr15_+_96869156 0.811 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr11_+_7506599 0.810 NM_198474
OLFML1
olfactomedin-like 1
chr14_+_65878579 0.796 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr3_-_114343052 0.789 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_120687956 0.781 NM_025157
PXN
paxillin
chr3_+_169940214 0.764 NM_002740
PRKCI
protein kinase C, iota
chr2_-_75788027 0.764 FAM176A
family with sequence similarity 176, member A
chr17_-_40575117 0.761 NM_012232
PTRF
polymerase I and transcript release factor
chr4_+_41540187 0.752 LIMCH1
LIM and calponin homology domains 1
chr18_+_77155943 0.740 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr6_+_123110345 0.738 SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr8_+_70378858 0.733 NM_001128204
NM_015170
SULF1

sulfatase 1

chr9_+_35749321 0.724 RGP1
RGP1 retrograde golgi transport homolog (S. cerevisiae)
chr2_+_33701320 0.721 NM_001139488
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr14_-_21271002 0.717 NM_002933
NM_198234
NM_198235
RNASE1


ribonuclease, RNase A family, 1 (pancreatic)


chr4_-_186877869 0.711 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr6_-_75915566 0.706 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr12_+_29376596 0.697 NM_018099
FAR2
fatty acyl CoA reductase 2
chr13_+_92050874 0.685 NM_004466
GPC5
glypican 5
chr2_-_75788079 0.681 NM_001135032
FAM176A
family with sequence similarity 176, member A
chr6_+_52930222 0.679 NM_033480
FBXO9
F-box protein 9
chr3_-_112359863 0.658 CCDC80
coiled-coil domain containing 80
chr16_-_47495095 0.657 ITFG1
integrin alpha FG-GAP repeat containing 1
chr20_-_23062786 0.656 CD93
CD93 molecule
chr14_+_21457964 0.652 NM_001029991
NM_022734
METTL17

methyltransferase like 17

chr11_-_119066583 0.639 NM_001145018
CCDC153
coiled-coil domain containing 153
chrX_-_74376075 0.637 NM_004299
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr2_-_220407818 0.629 NM_001195731
CHPF
chondroitin polymerizing factor
chr10_-_11574273 0.620 NM_001080491
USP6NL
USP6 N-terminal like
chr3_+_169940246 0.606 PRKCI
protein kinase C, iota
chr16_+_2521499 0.605 NM_006181
NTN3
netrin 3
chr11_+_121461070 0.604 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr12_-_80084742 0.598 NM_002583
PAWR
PRKC, apoptosis, WT1, regulator
chr16_+_77225094 0.578 MON1B
MON1 homolog B (yeast)
chr14_+_95047730 0.575 NM_000624
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr16_+_47495225 0.572 PHKB
phosphorylase kinase, beta
chr1_+_26485510 0.571 NM_024869
FAM110D
family with sequence similarity 110, member D
chr6_+_52929795 0.571 NM_033481
FBXO9
F-box protein 9
chr18_-_53068755 0.568 TCF4
transcription factor 4
chr17_-_46799879 0.566 NM_032391
PRAC
prostate cancer susceptibility candidate
chr4_+_126237566 0.564 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chr17_+_34171647 0.561 TAF15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chrX_+_54947228 0.560 NM_001039705
NM_016157
NM_177556
TRO


trophinin


chr11_-_33891485 0.545 NM_001142315
LMO2
LIM domain only 2 (rhombotin-like 1)
chr3_+_169940223 0.540 PRKCI
protein kinase C, iota
chr13_+_20207780 0.540 NM_017520
MPHOSPH8
M-phase phosphoprotein 8
chr5_-_177423242 0.532 NM_006261
PROP1
PROP paired-like homeobox 1
chr6_+_155411422 0.530 NM_012454
TIAM2
T-cell lymphoma invasion and metastasis 2
chr5_+_42565562 0.527 NM_001242406
GHR
growth hormone receptor
chr1_-_54518915 0.519 TMEM59
transmembrane protein 59
chr15_+_75941347 0.513 NM_153271
SNX33
sorting nexin 33
chr9_-_34662629 0.511 NM_006664
CCL27
chemokine (C-C motif) ligand 27
chr4_+_140587086 0.508 MGST2
microsomal glutathione S-transferase 2
chr12_-_13153200 0.508 NM_015987
HEBP1
heme binding protein 1
chr19_+_45409003 0.508 NM_000041
APOE
apolipoprotein E
chr4_+_41614725 0.503 LIMCH1
LIM and calponin homology domains 1
chr11_-_71746966 0.503


chr22_+_32439103 0.501 SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr19_+_14491920 0.497 NM_001025160
NM_001784
NM_078481
CD97


CD97 molecule


chr2_-_61697899 0.497 USP34
ubiquitin specific peptidase 34
chr1_-_54518886 0.496 TMEM59
transmembrane protein 59
chr1_-_16344438 0.494 HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr3_-_112359962 0.494 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr13_-_41837619 0.492 NM_004294
MTRF1
mitochondrial translational release factor 1
chr2_-_192711923 0.488 NM_004657
SDPR
serum deprivation response
chr15_-_34659245 0.488 NM_153613
LPCAT4
lysophosphatidylcholine acyltransferase 4
chr18_+_77155714 0.488 NM_006162
NM_172388
NM_172390
NFATC1


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1


chr3_+_50306578 0.487 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr6_+_30850693 0.487 DDR1
discoidin domain receptor tyrosine kinase 1
chr11_+_92085261 0.484 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr17_-_15973760 0.483 NCOR1
nuclear receptor corepressor 1
chr3_+_25469833 0.481 NM_000965
RARB
retinoic acid receptor, beta
chr12_-_58240746 0.479 NM_005730
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr5_-_95158365 0.479 GLRX
glutaredoxin (thioltransferase)
chr22_-_22089975 0.475 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr11_-_33891361 0.474 NM_001142316
LMO2
LIM domain only 2 (rhombotin-like 1)
chr8_-_103666018 0.469 NM_001032282
KLF10
Kruppel-like factor 10
chr10_-_33247131 0.469 ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr1_-_54518790 0.468 TMEM59
transmembrane protein 59
chr8_-_146202727 0.463 ZNF252
zinc finger protein 252
chrY_+_16634487 0.462 NM_001206850
NLGN4Y
neuroligin 4, Y-linked
chr12_+_27677044 0.462 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr15_+_77287428 0.462 NM_003978
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr10_-_33247178 0.461 NM_002211
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr17_-_58469577 0.459 NM_032582
USP32
ubiquitin specific peptidase 32
chr11_-_47470687 0.458 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr16_+_29823408 0.457 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr7_+_150434435 0.453 NM_018384
GIMAP5
GTPase, IMAP family member 5
chr14_-_23904849 0.452 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr12_+_3068442 0.449 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4


chr16_+_29823557 0.448 PRRT2
proline-rich transmembrane protein 2
chr2_+_103089761 0.447 NM_001011552
SLC9A4
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr12_-_13153047 0.445 HEBP1
heme binding protein 1
chr1_+_100315631 0.441 NM_000642
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr7_+_142985307 0.438 NM_032982
NM_032983
CASP2

caspase 2, apoptosis-related cysteine peptidase

chrX_-_2882288 0.433 NM_000047
ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr17_-_8079607 0.420 NM_032354
NM_183065
TMEM107

transmembrane protein 107

chr3_-_66024508 0.418 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr14_-_74180341 0.415 NM_006029
PNMA1
paraneoplastic antigen MA1
chr18_+_77155966 0.415 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr5_-_151066492 0.414 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr14_-_77494621 0.413 IRF2BPL
interferon regulatory factor 2 binding protein-like
chr2_-_192711651 0.412 SDPR
serum deprivation response
chr18_+_3247825 0.411 MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chrX_-_10851808 0.410 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr4_+_140586921 0.406 NM_001204366
NM_001204367
NM_001204368
NM_002413
MGST2



microsomal glutathione S-transferase 2



chr18_+_3247815 0.403 MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr7_+_102715616 0.401 ARMC10
armadillo repeat containing 10
chr10_+_35456443 0.400 NM_182771
NM_182772
CREM

cAMP responsive element modulator

chr1_-_6296034 0.400 NM_012405
ICMT
isoprenylcysteine carboxyl methyltransferase
chr1_-_17307107 0.399 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr5_-_9630462 0.395 NM_019599
TAS2R1
taste receptor, type 2, member 1
chr15_+_77287688 0.394 PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr3_-_112359277 0.392 CCDC80
coiled-coil domain containing 80
chr20_+_33759773 0.391 NM_006404
PROCR
protein C receptor, endothelial
chr5_-_55290601 0.390 NM_001190981
NM_002184
NM_175767
IL6ST


interleukin 6 signal transducer (gp130, oncostatin M receptor)


chr15_-_49338496 0.390 NM_001193489
NM_014701
SECISBP2L

SECIS binding protein 2-like

chr5_-_138842291 0.389 NM_001077693
ECSCR
endothelial cell-specific chemotaxis regulator
chr1_-_179198735 0.389 ABL2
v-abl Abelson murine leukemia viral oncogene homolog 2
chr5_-_38595506 0.388 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr3_+_50306305 0.388 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr12_+_120933911 0.387 DYNLL1
dynein, light chain, LC8-type 1
chr17_+_45286427 0.379 NM_001002841
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr15_+_77287738 0.378 PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr1_+_28764660 0.378 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr2_-_183387063 0.377 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr3_+_47029453 0.375 NBEAL2
neurobeachin-like 2
chr11_-_6643809 0.375 DCHS1
dachsous 1 (Drosophila)
chr1_-_54519050 0.373 NM_004872
TMEM59
transmembrane protein 59
chrX_+_107683015 0.371 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chr5_-_95158465 0.367 NM_001118890
NM_001243658
NM_001243659
NM_002064
GLRX



glutaredoxin (thioltransferase)



chr5_-_151066445 0.367 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr1_+_145524989 0.361 NM_003637
ITGA10
integrin, alpha 10
chr5_+_10353802 0.361 NM_005885
MARCH6
membrane-associated ring finger (C3HC4) 6
chr15_-_69707358 0.360 LOC145694
uncharacterized LOC145694
chr1_+_100315806 0.357 NM_000028
NM_000643
NM_000644
AGL


amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase


chr15_-_59665053 0.357 MYO1E
myosin IE
chr16_+_47495166 0.355 NM_000293
NM_001031835
PHKB

phosphorylase kinase, beta


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.49 3.72e-02 GO:0010324 membrane invagination

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.56 1.23e-03 GO:0019838 growth factor binding
21.16 4.98e-02 GO:0005127 ciliary neurotrophic factor receptor binding