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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: TFDP1.p2

Z-value: 1.774

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_-_122746544	2.838		SEMA5B	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr9_+_103235634	2.378		TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr4_-_174450529	2.318		HAND2	heart and neural crest derivatives expressed 2
chr6_+_34205029	2.173		HMGA1	high mobility group AT-hook 1
chr6_+_37137882	2.107	NM_001243186 NM_002648	PIM1	pim-1 oncogene
chr6_+_4776826	2.064		CDYL	chromodomain protein, Y-like
chr17_-_31204071	2.005		MYO1D	myosin ID
chr12_-_120554558	1.964		RAB35	RAB35, member RAS oncogene family
chr16_+_67063214	1.937		CBFB	core-binding factor, beta subunit
chr1_+_25071967	1.911		CLIC4	chloride intracellular channel 4
chr18_-_48723689	1.883		MEX3C	mex-3 homolog C (C. elegans)
chr9_+_103235489	1.873	NM_003692	TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr12_-_120554453	1.844		RAB35	RAB35, member RAS oncogene family
chr2_-_225907312	1.806	NM_014689	DOCK10	dedicator of cytokinesis 10
chr9_-_115095786	1.753		PTBP3	polypyrimidine tract binding protein 3
chr1_+_25071906	1.695		CLIC4	chloride intracellular channel 4
chr5_+_154135029	1.663		LARP1	La ribonucleoprotein domain family, member 1
chr12_-_120554551	1.615		RAB35	RAB35, member RAS oncogene family
chr6_-_143266283	1.520	NM_006734	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr12_+_53773924	1.501	NM_001251825 NM_138473	SP1	Sp1 transcription factor
chr12_+_111471827	1.475	NM_015267	CUX2	cut-like homeobox 2
chr8_-_37756971	1.468	NM_001002814 NM_025151	RAB11FIP1	RAB11 family interacting protein 1 (class I)
chr3_-_127541160	1.463	NM_007283	MGLL	monoglyceride lipase
chr3_+_133292714	1.444		CDV3	CDV3 homolog (mouse)
chr1_+_4715104	1.422	NM_001042478 NM_018836	AJAP1	adherens junctions associated protein 1
chr20_-_20693122	1.417	NM_020343	RALGAPA2	Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr17_-_63052707	1.410		GNA13	guanine nucleotide binding protein (G protein), alpha 13
chr2_-_11484699	1.386	NM_004850	ROCK2	Rho-associated, coiled-coil containing protein kinase 2
chr7_+_77166331	1.374		PTPN12	protein tyrosine phosphatase, non-receptor type 12
chr19_+_17666381	1.368		GLT25D1	glycosyltransferase 25 domain containing 1
chr9_-_115095933	1.361	NM_001163788 NM_001163790 NM_001244896 NM_001244897 NM_005156	PTBP3	polypyrimidine tract binding protein 3
chr3_-_127541975	1.358	NM_001003794	MGLL	monoglyceride lipase
chr14_+_21538339	1.351	NM_018071	ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40
chr2_+_236402948	1.337		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr15_+_67358194	1.328	NM_005902	SMAD3	SMAD family member 3
chr7_+_65338343	1.324		VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1
chr15_-_64338519	1.320	NM_014326	DAPK2	death-associated protein kinase 2
chr4_-_83350829	1.320		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr3_-_47823343	1.295		SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr12_+_53774422	1.291	NM_003109	SP1	Sp1 transcription factor
chr7_+_45614081	1.276	NM_021116	ADCY1	adenylate cyclase 1 (brain)
chr17_-_63052816	1.272
chr12_-_121734474	1.265		CAMKK2	calcium/calmodulin-dependent protein kinase kinase 2, beta
chr2_+_239756672	1.264	NM_057179	TWIST2	twist homolog 2 (Drosophila)
chr17_-_63052744	1.247		GNA13	guanine nucleotide binding protein (G protein), alpha 13
chr3_+_133292557	1.246		CDV3	CDV3 homolog (mouse)
chr5_+_127419407	1.244	NM_001046	SLC12A2	solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr1_-_32229635	1.239	NM_001703	BAI2	brain-specific angiogenesis inhibitor 2
chr15_+_44719765	1.216		CTDSPL2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr1_+_25071759	1.209	NM_013943	CLIC4	chloride intracellular channel 4
chr9_+_82187599	1.199		TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr5_+_10564431	1.181	NM_001164440	ANKRD33B	ankyrin repeat domain 33B
chr11_-_125933186	1.174	NM_001243597 NM_016952	CDON	Cdon homolog (mouse)
chr5_-_137089990	1.172		HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr17_+_47653474	1.169		NXPH3	neurexophilin 3
chr7_-_22396511	1.163	NM_012294	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr5_-_137090049	1.150
chr7_-_105925329	1.145		NAMPT	nicotinamide phosphoribosyltransferase
chr1_-_184943532	1.144		FAM129A	family with sequence similarity 129, member A
chr11_-_110167191	1.143	NM_002906	RDX	radixin
chr3_-_27525806	1.136		SLC4A7	solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr12_-_88974094	1.134	NM_000899 NM_003994	KITLG	KIT ligand
chr6_+_4776641	1.123	NM_004824	CDYL	chromodomain protein, Y-like
chr12_-_121734543	1.118	NM_172226	CAMKK2	calcium/calmodulin-dependent protein kinase kinase 2, beta
chr5_+_56111379	1.109		MAP3K1	mitogen-activated protein kinase kinase kinase 1
chrX_-_109561427	1.106		AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr1_-_212003576	1.103		LPGAT1	lysophosphatidylglycerol acyltransferase 1
chr17_-_79849457	1.089	NM_005782	THOC4	THO complex 4
chr14_+_32546171	1.088		ARHGAP5	Rho GTPase activating protein 5
chr20_+_42086533	1.087		SRSF6	serine/arginine-rich splicing factor 6
chr1_+_114472438	1.077		HIPK1	homeodomain interacting protein kinase 1
chr4_+_38665587	1.074	NM_016531	KLF3	Kruppel-like factor 3 (basic)
chr17_+_27717942	1.059	NM_020791 NM_025142	TAOK1	TAO kinase 1
chr2_+_46769892	1.055		RHOQ	ras homolog gene family, member Q
chr19_+_51815095	1.038	NM_001101372	IGLON5	IgLON family member 5
chr3_-_160283166	1.032		KPNA4	karyopherin alpha 4 (importin alpha 3)
chr6_+_34204928	1.024		HMGA1	high mobility group AT-hook 1
chr16_+_50776012	1.020	NM_001042412	CYLD	cylindromatosis (turban tumor syndrome)
chr12_-_42631982	1.018	NM_001190977	YAF2	YY1 associated factor 2
chr1_-_21113758	1.013		HP1BP3	heterochromatin protein 1, binding protein 3
chr10_+_28822508	1.007		WAC	WW domain containing adaptor with coiled-coil
chr8_-_8750739	1.005	NM_004225	MFHAS1	malignant fibrous histiocytoma amplified sequence 1
chr3_-_167813058	1.001		GOLIM4	golgi integral membrane protein 4
chr16_+_56225301	0.999		GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr5_+_113698015	0.996	NM_021614	KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr8_-_141645603	0.993	NM_001164623 NM_012154	EIF2C2	eukaryotic translation initiation factor 2C, 2
chr10_-_61666184	0.992		CCDC6	coiled-coil domain containing 6
chr7_+_65338161	0.992	NM_173517	VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1
chr21_+_43639202	0.983	NM_004915 NM_016818	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr11_+_46299585	0.976		CREB3L1	cAMP responsive element binding protein 3-like 1
chr2_+_100721380	0.972
chr12_-_58132028	0.967	NM_001122772	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr1_-_21113798	0.964		HP1BP3	heterochromatin protein 1, binding protein 3
chr3_-_47823275	0.959		SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr1_-_65431826	0.951	NM_002227	JAK1	Janus kinase 1
chr5_+_113698304	0.949		KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr4_+_1873149	0.944		WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr15_+_90931489	0.943		IQGAP1	IQ motif containing GTPase activating protein 1
chr20_-_41818464	0.932	NM_007050 NM_133170	PTPRT	protein tyrosine phosphatase, receptor type, T
chr2_-_61697846	0.932	NM_014709	USP34	ubiquitin specific peptidase 34
chr2_+_236403290	0.931		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr11_-_59436366	0.920		PATL1	protein associated with topoisomerase II homolog 1 (yeast)
chr22_-_22221937	0.912		MAPK1	mitogen-activated protein kinase 1
chr2_+_42396392	0.909	NM_001145076 NM_019063	EML4	echinoderm microtubule associated protein like 4
chr3_-_47823368	0.903		SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr4_+_128982404	0.903		LARP1B	La ribonucleoprotein domain family, member 1B
chr6_-_13711484	0.903		RANBP9	RAN binding protein 9
chr5_-_137089754	0.901		HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr1_-_21113147	0.898		HP1BP3	heterochromatin protein 1, binding protein 3
chr7_-_139477437	0.895	NM_001113239 NM_022740	HIPK2	homeodomain interacting protein kinase 2
chr6_-_13711643	0.894	NM_005493	RANBP9	RAN binding protein 9
chr21_+_44394691	0.893		PKNOX1	PBX/knotted 1 homeobox 1
chr10_-_32636084	0.890	NM_025209	EPC1	enhancer of polycomb homolog 1 (Drosophila)
chr12_-_50101127	0.884		FMNL3	formin-like 3
chrX_+_24167861	0.881		ZFX	zinc finger protein, X-linked
chr15_+_44719578	0.878	NM_016396	CTDSPL2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr1_+_4714668	0.875		AJAP1	adherens junctions associated protein 1
chr3_+_41240995	0.875		CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa
chr4_+_20255234	0.873	NM_004787	SLIT2	slit homolog 2 (Drosophila)
chr16_+_2039945	0.867	NM_004209	SYNGR3	synaptogyrin 3
chr11_+_118307072	0.866	NM_001197104 NM_005933	MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
chr3_-_160283071	0.862		KPNA4	karyopherin alpha 4 (importin alpha 3)
chr2_-_69614321	0.857	NM_001244710 NM_002056	GFPT1	glutamine--fructose-6-phosphate transaminase 1
chr13_+_98086681	0.855		RAP2A	RAP2A, member of RAS oncogene family
chr3_-_47823333	0.851		SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr4_-_39979159	0.848		PDS5A	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr3_-_47823419	0.847		SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr4_+_103422730	0.844		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr12_-_120554612	0.842	NM_001167606 NM_006861	RAB35	RAB35, member RAS oncogene family
chr17_-_6459746	0.832	NM_001165966 NM_031220	PITPNM3	PITPNM family member 3
chr1_-_110613233	0.832	NM_006492	ALX3	ALX homeobox 3
chr15_+_67358161	0.830		SMAD3	SMAD family member 3
chr22_-_46373007	0.828	NM_058238	WNT7B	wingless-type MMTV integration site family, member 7B
chr13_-_30169795	0.827	NM_003045	SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr5_-_137090033	0.826		HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr12_-_129308293	0.826	NM_145648	SLC15A4	solute carrier family 15, member 4
chr5_-_32444729	0.824		ZFR	zinc finger RNA binding protein
chr9_+_82187469	0.822		TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr11_-_59436488	0.817	NM_152716	PATL1	protein associated with topoisomerase II homolog 1 (yeast)
chr20_+_31407696	0.815	NM_012325	MAPRE1	microtubule-associated protein, RP/EB family, member 1
chr2_-_61697899	0.810		USP34	ubiquitin specific peptidase 34
chr6_+_43139201	0.809		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr7_+_39990108	0.807		CDK13	cyclin-dependent kinase 13
chr3_+_133292404	0.806	NM_001134422 NM_017548	CDV3	CDV3 homolog (mouse)
chr16_+_50775960	0.806	NM_001042355 NM_015247	CYLD	cylindromatosis (turban tumor syndrome)
chr9_+_103189494	0.804	NM_001198807 NM_080655 NM_001198805	C9orf30	chromosome 9 open reading frame 30
chr19_+_45504686	0.802	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr7_-_98741605	0.791		SMURF1	SMAD specific E3 ubiquitin protein ligase 1
chr20_+_31407777	0.789		MAPRE1	microtubule-associated protein, RP/EB family, member 1
chr15_+_44719831	0.789		CTDSPL2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr6_-_86352696	0.779		SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr1_-_226374400	0.771		ACBD3	acyl-CoA binding domain containing 3
chr22_-_50221445	0.770		BRD1	bromodomain containing 1
chr15_-_59041777	0.768		ADAM10	ADAM metallopeptidase domain 10
chr2_+_223725675	0.768	NM_004457 NM_203372	ACSL3	acyl-CoA synthetase long-chain family member 3
chr16_-_11680756	0.766	NM_001136472 NM_001136473	LITAF	lipopolysaccharide-induced TNF factor
chr19_-_7293876	0.764	NM_000208 NM_001079817	INSR	insulin receptor
chr10_+_12391708	0.763		CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr11_-_10830034	0.761		EIF4G2	eukaryotic translation initiation factor 4 gamma, 2
chr3_+_133293256	0.759	NM_001134423	CDV3	CDV3 homolog (mouse)
chr15_+_52311432	0.758		MAPK6	mitogen-activated protein kinase 6
chr6_+_43139190	0.756		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr3_+_140770412	0.754		SPSB4	splA/ryanodine receptor domain and SOCS box containing 4
chr5_+_138089073	0.754	NM_001903	CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa
chr1_-_6240082	0.753	NM_015557	CHD5	chromodomain helicase DNA binding protein 5
chr22_-_19418998	0.752		HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr6_-_13711952	0.751		RANBP9	RAN binding protein 9
chr7_-_28220146	0.751		JAZF1	JAZF zinc finger 1
chr9_+_129622935	0.748	NM_001099270	ZBTB34	zinc finger and BTB domain containing 34
chr12_+_57610577	0.744	NM_007224	NXPH4	neurexophilin 4
chr19_+_16187306	0.743		TPM4	tropomyosin 4
chr5_+_118604504	0.742		TNFAIP8	tumor necrosis factor, alpha-induced protein 8
chr12_+_98909405	0.740		TMPO	thymopoietin
chr9_+_101867392	0.738		TGFBR1	transforming growth factor, beta receptor 1
chr11_-_72353435	0.737	NM_001143839 NM_001243784	PDE2A	phosphodiesterase 2A, cGMP-stimulated
chr1_-_156721501	0.737	NM_004494	HDGF	hepatoma-derived growth factor
chr15_-_45815001	0.736	NM_013309	SLC30A4	solute carrier family 30 (zinc transporter), member 4
chr22_-_50221195	0.735		BRD1	bromodomain containing 1
chr17_-_79849362	0.733		THOC4	THO complex 4
chr7_-_98741375	0.731		SMURF1	SMAD specific E3 ubiquitin protein ligase 1
chr18_-_78005230	0.730	NM_032510	PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)
chr6_-_17987693	0.728		KIF13A	kinesin family member 13A
chr5_+_126853308	0.726	NM_130809	PRRC1	proline-rich coiled-coil 1
chr8_+_144816287	0.725		LOC100128338	uncharacterized LOC100128338
chr14_+_32546208	0.724		ARHGAP5	Rho GTPase activating protein 5
chr9_+_101867401	0.723	NM_001130916 NM_004612	TGFBR1	transforming growth factor, beta receptor 1
chr19_+_16187266	0.721		TPM4	tropomyosin 4
chr8_-_140715234	0.721	NM_016601	KCNK9	potassium channel, subfamily K, member 9
chr1_+_62902708	0.721		USP1	ubiquitin specific peptidase 1
chr1_+_62902325	0.720	NM_003368	USP1	ubiquitin specific peptidase 1
chr11_+_34073889	0.719		CAPRIN1	cell cycle associated protein 1
chr19_-_47734215	0.718	NM_014417	BBC3	BCL2 binding component 3
chr7_+_45614179	0.717		ADCY1	adenylate cyclase 1 (brain)
chr7_+_77166750	0.716	NM_002835	PTPN12	protein tyrosine phosphatase, non-receptor type 12
chr15_+_52311438	0.716		MAPK6	mitogen-activated protein kinase 6
chr5_+_118604417	0.716	NM_001077654	TNFAIP8	tumor necrosis factor, alpha-induced protein 8
chr8_-_133493003	0.716	NM_004519	KCNQ3	potassium voltage-gated channel, KQT-like subfamily, member 3
chr6_-_137113166	0.715
chr6_+_135502521	0.714		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr12_-_25403809	0.714		KRAS	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.12	1.86e-44	GO:0009987	cellular process
1.26	4.59e-37	GO:0044260	cellular macromolecule metabolic process
1.19	9.16e-34	GO:0044237	cellular metabolic process
1.30	3.26e-26	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31	4.38e-26	GO:0071842	cellular component organization at cellular level
1.20	4.55e-26	GO:0043170	macromolecule metabolic process
1.17	5.37e-25	GO:0044238	primary metabolic process
1.29	7.22e-25	GO:0071841	cellular component organization or biogenesis at cellular level
1.26	1.69e-24	GO:0016043	cellular component organization
1.24	3.33e-23	GO:0071840	cellular component organization or biogenesis
1.25	4.77e-23	GO:0006807	nitrogen compound metabolic process
1.26	1.16e-22	GO:0034641	cellular nitrogen compound metabolic process
1.14	4.05e-22	GO:0008152	metabolic process
1.14	5.22e-21	GO:0050794	regulation of cellular process
1.27	5.46e-19	GO:0044267	cellular protein metabolic process
1.29	6.26e-19	GO:0090304	nucleic acid metabolic process
1.22	1.30e-18	GO:0031323	regulation of cellular metabolic process
1.13	3.42e-17	GO:0050789	regulation of biological process
1.21	3.48e-17	GO:0080090	regulation of primary metabolic process
1.19	1.48e-16	GO:0019222	regulation of metabolic process
1.21	1.70e-16	GO:0060255	regulation of macromolecule metabolic process
1.30	2.90e-16	GO:0006464	protein modification process
1.31	7.24e-16	GO:0034645	cellular macromolecule biosynthetic process
1.31	7.81e-15	GO:0006996	organelle organization
1.42	8.02e-15	GO:0022008	neurogenesis
1.30	8.97e-15	GO:0009059	macromolecule biosynthetic process
1.11	1.17e-14	GO:0065007	biological regulation
1.32	2.96e-14	GO:0007399	nervous system development
1.24	3.44e-14	GO:0044249	cellular biosynthetic process
1.42	7.31e-14	GO:0048699	generation of neurons
1.27	1.67e-13	GO:0043412	macromolecule modification
1.28	5.28e-13	GO:0016070	RNA metabolic process
1.22	1.00e-12	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.23	1.05e-12	GO:0009058	biosynthetic process
1.21	1.26e-12	GO:0051171	regulation of nitrogen compound metabolic process
1.38	1.53e-12	GO:0032774	RNA biosynthetic process
1.26	4.17e-12	GO:0010467	gene expression
1.19	2.12e-11	GO:0048856	anatomical structure development
1.38	2.53e-11	GO:0006351	transcription, DNA-dependent
1.43	2.56e-11	GO:0030182	neuron differentiation
1.23	2.76e-11	GO:0048523	negative regulation of cellular process
1.35	2.91e-11	GO:0007049	cell cycle
1.21	3.19e-11	GO:0010468	regulation of gene expression
1.36	3.65e-11	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.17	3.74e-11	GO:0032502	developmental process
1.21	3.83e-11	GO:0031326	regulation of cellular biosynthetic process
1.22	4.07e-11	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.24	5.22e-11	GO:0048869	cellular developmental process
1.20	5.79e-11	GO:0009889	regulation of biosynthetic process
1.44	1.09e-10	GO:0030030	cell projection organization
1.21	1.31e-10	GO:0048522	positive regulation of cellular process
1.17	1.40e-10	GO:0007275	multicellular organismal development
1.28	1.60e-10	GO:0009653	anatomical structure morphogenesis
1.36	3.14e-10	GO:0048468	cell development
1.19	3.39e-10	GO:0019538	protein metabolic process
1.19	3.42e-10	GO:0048731	system development
1.23	6.35e-10	GO:0030154	cell differentiation
1.44	1.06e-09	GO:0000902	cell morphogenesis
1.26	1.09e-09	GO:0023051	regulation of signaling
1.20	1.40e-09	GO:0010556	regulation of macromolecule biosynthetic process
1.48	1.51e-09	GO:0031175	neuron projection development
1.27	2.69e-09	GO:0009966	regulation of signal transduction
1.21	2.78e-09	GO:0051252	regulation of RNA metabolic process
1.19	3.97e-09	GO:0048518	positive regulation of biological process
1.20	5.80e-09	GO:0048519	negative regulation of biological process
1.41	7.54e-09	GO:0032989	cellular component morphogenesis
1.41	1.08e-08	GO:0051726	regulation of cell cycle
1.41	1.27e-08	GO:0051276	chromosome organization
1.42	2.07e-08	GO:0048666	neuron development
1.45	2.57e-08	GO:0000904	cell morphogenesis involved in differentiation
1.26	4.71e-08	GO:0035556	intracellular signal transduction
1.44	4.80e-08	GO:0032990	cell part morphogenesis
1.48	5.61e-08	GO:0007409	axonogenesis
1.44	5.92e-08	GO:0048858	cell projection morphogenesis
1.46	1.08e-07	GO:0048812	neuron projection morphogenesis
1.47	1.10e-07	GO:0048667	cell morphogenesis involved in neuron differentiation
1.34	1.66e-07	GO:0022402	cell cycle process
1.34	2.18e-07	GO:0051173	positive regulation of nitrogen compound metabolic process
1.51	2.56e-07	GO:0051301	cell division
1.34	4.84e-07	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32	5.59e-07	GO:0033554	cellular response to stress
1.39	7.29e-07	GO:0000278	mitotic cell cycle
1.26	8.26e-07	GO:0009893	positive regulation of metabolic process
1.19	9.30e-07	GO:0006355	regulation of transcription, DNA-dependent
1.26	1.02e-06	GO:0031325	positive regulation of cellular metabolic process
1.29	1.20e-06	GO:0006793	phosphorus metabolic process
1.29	1.20e-06	GO:0006796	phosphate metabolic process
1.50	1.48e-06	GO:0007411	axon guidance
1.35	1.86e-06	GO:0022403	cell cycle phase
1.27	2.51e-06	GO:0022607	cellular component assembly
1.46	2.56e-06	GO:0007264	small GTPase mediated signal transduction
1.41	2.72e-06	GO:0034621	cellular macromolecular complex subunit organization
1.26	3.97e-06	GO:0010604	positive regulation of macromolecule metabolic process
1.34	4.58e-06	GO:0051254	positive regulation of RNA metabolic process
1.27	5.51e-06	GO:0008104	protein localization
1.27	5.57e-06	GO:0032268	regulation of cellular protein metabolic process
1.30	6.08e-06	GO:0043933	macromolecular complex subunit organization
1.22	6.38e-06	GO:0065009	regulation of molecular function
1.29	6.96e-06	GO:0010605	negative regulation of macromolecule metabolic process
1.50	7.64e-06	GO:0048285	organelle fission
1.40	7.65e-06	GO:0006325	chromatin organization
1.30	8.04e-06	GO:0031328	positive regulation of cellular biosynthetic process
1.51	8.32e-06	GO:0000280	nuclear division
1.51	8.32e-06	GO:0007067	mitosis
1.40	1.09e-05	GO:0045859	regulation of protein kinase activity
1.29	1.35e-05	GO:0009891	positive regulation of biosynthetic process
1.32	1.59e-05	GO:0065003	macromolecular complex assembly
1.23	1.92e-05	GO:0051641	cellular localization
1.31	2.29e-05	GO:0071844	cellular component assembly at cellular level
1.23	2.33e-05	GO:0033036	macromolecule localization
1.49	2.39e-05	GO:0000087	M phase of mitotic cell cycle
1.34	2.47e-05	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.38	2.49e-05	GO:0043549	regulation of kinase activity
1.44	3.97e-05	GO:0034622	cellular macromolecular complex assembly
1.37	5.95e-05	GO:0051338	regulation of transferase activity
1.23	6.72e-05	GO:0044085	cellular component biogenesis
1.27	7.40e-05	GO:0031324	negative regulation of cellular metabolic process
1.33	7.51e-05	GO:0045893	positive regulation of transcription, DNA-dependent
1.29	1.01e-04	GO:0046907	intracellular transport
1.30	1.11e-04	GO:0010557	positive regulation of macromolecule biosynthetic process
1.39	1.17e-04	GO:0000279	M phase
1.24	1.69e-04	GO:0051246	regulation of protein metabolic process
1.35	1.78e-04	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.25	1.82e-04	GO:0009892	negative regulation of metabolic process
1.53	1.87e-04	GO:0048011	nerve growth factor receptor signaling pathway
1.31	1.98e-04	GO:0007167	enzyme linked receptor protein signaling pathway
1.12	2.16e-04	GO:0023052	signaling
1.23	2.31e-04	GO:0050790	regulation of catalytic activity
1.46	2.62e-04	GO:0006366	transcription from RNA polymerase II promoter
1.30	2.81e-04	GO:0010628	positive regulation of gene expression
1.30	3.47e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.27	3.66e-04	GO:0044093	positive regulation of molecular function
1.36	3.73e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.32	4.36e-04	GO:0006259	DNA metabolic process
1.31	5.78e-04	GO:0010629	negative regulation of gene expression
1.28	6.55e-04	GO:0006468	protein phosphorylation
1.29	6.57e-04	GO:0043085	positive regulation of catalytic activity
1.69	7.40e-04	GO:0007265	Ras protein signal transduction
1.57	7.89e-04	GO:0030900	forebrain development
1.25	8.05e-04	GO:0045184	establishment of protein localization
1.29	8.21e-04	GO:0031327	negative regulation of cellular biosynthetic process
1.28	8.69e-04	GO:0009890	negative regulation of biosynthetic process
1.26	9.18e-04	GO:0016310	phosphorylation
1.26	9.77e-04	GO:0051128	regulation of cellular component organization
1.40	9.86e-04	GO:0010564	regulation of cell cycle process
1.41	1.00e-03	GO:0070647	protein modification by small protein conjugation or removal
1.12	1.00e-03	GO:0051179	localization
1.30	1.01e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.23	1.03e-03	GO:0010941	regulation of cell death
1.39	1.23e-03	GO:0016568	chromatin modification
1.10	1.28e-03	GO:0051716	cellular response to stimulus
1.32	1.53e-03	GO:0051253	negative regulation of RNA metabolic process
1.70	1.58e-03	GO:0031098	stress-activated protein kinase signaling cascade
1.22	1.60e-03	GO:0043067	regulation of programmed cell death
1.25	1.61e-03	GO:0016265	death
1.32	1.69e-03	GO:0016071	mRNA metabolic process
1.26	1.73e-03	GO:0031399	regulation of protein modification process
1.33	1.85e-03	GO:0007417	central nervous system development
1.32	1.86e-03	GO:0006974	response to DNA damage stimulus
1.29	2.01e-03	GO:0001932	regulation of protein phosphorylation
1.44	2.02e-03	GO:0032446	protein modification by small protein conjugation
1.32	2.05e-03	GO:0034613	cellular protein localization
1.51	2.11e-03	GO:0000375	RNA splicing, via transesterification reactions
1.30	2.15e-03	GO:0071822	protein complex subunit organization
1.28	2.15e-03	GO:0045595	regulation of cell differentiation
1.22	2.23e-03	GO:0042981	regulation of apoptosis
1.44	2.24e-03	GO:0010608	posttranscriptional regulation of gene expression
1.29	2.25e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
1.43	2.39e-03	GO:0071900	regulation of protein serine/threonine kinase activity
1.31	2.48e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.28	2.59e-03	GO:0042325	regulation of phosphorylation
1.27	2.66e-03	GO:0019220	regulation of phosphate metabolic process
1.27	2.66e-03	GO:0051174	regulation of phosphorus metabolic process
1.30	2.68e-03	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.24	2.80e-03	GO:0008219	cell death
1.11	2.89e-03	GO:0007165	signal transduction
1.27	2.91e-03	GO:0009790	embryo development
1.48	3.59e-03	GO:0000075	cell cycle checkpoint
1.63	3.65e-03	GO:0006403	RNA localization
1.31	3.66e-03	GO:0070727	cellular macromolecule localization
1.50	3.94e-03	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.50	3.94e-03	GO:0000398	nuclear mRNA splicing, via spliceosome
1.37	4.24e-03	GO:0007420	brain development
1.64	4.34e-03	GO:0050657	nucleic acid transport
1.64	4.34e-03	GO:0050658	RNA transport
1.64	4.34e-03	GO:0051236	establishment of RNA localization
1.24	4.68e-03	GO:0015031	protein transport
1.73	4.74e-03	GO:0021537	telencephalon development
1.47	4.80e-03	GO:0071156	regulation of cell cycle arrest
1.88	4.82e-03	GO:0031124	mRNA 3'-end processing
1.43	5.13e-03	GO:0016567	protein ubiquitination
1.21	5.14e-03	GO:0010646	regulation of cell communication
1.21	6.13e-03	GO:0051649	establishment of localization in cell
1.37	7.79e-03	GO:0018193	peptidyl-amino acid modification
1.31	7.83e-03	GO:0006753	nucleoside phosphate metabolic process
1.31	7.83e-03	GO:0009117	nucleotide metabolic process
1.81	8.07e-03	GO:0071901	negative regulation of protein serine/threonine kinase activity
1.39	9.78e-03	GO:0008380	RNA splicing
1.38	1.05e-02	GO:0060284	regulation of cell development
1.34	1.10e-02	GO:0006397	mRNA processing
1.44	1.10e-02	GO:0003002	regionalization
1.65	1.20e-02	GO:0048736	appendage development
1.65	1.20e-02	GO:0060173	limb development
1.31	1.29e-02	GO:0048646	anatomical structure formation involved in morphogenesis
1.19	1.57e-02	GO:0044248	cellular catabolic process
1.83	1.66e-02	GO:0034138	toll-like receptor 3 signaling pathway
1.58	1.77e-02	GO:0030111	regulation of Wnt receptor signaling pathway
1.89	1.81e-02	GO:0007163	establishment or maintenance of cell polarity
1.24	2.03e-02	GO:0012501	programmed cell death
1.30	2.04e-02	GO:0072358	cardiovascular system development
1.30	2.04e-02	GO:0072359	circulatory system development
1.61	2.11e-02	GO:0006469	negative regulation of protein kinase activity
1.53	2.14e-02	GO:0046039	GTP metabolic process
1.55	2.25e-02	GO:0006184	GTP catabolic process
1.68	2.28e-02	GO:0030326	embryonic limb morphogenesis
1.68	2.28e-02	GO:0035113	embryonic appendage morphogenesis
1.42	2.34e-02	GO:0000165	MAPKKK cascade
1.44	2.51e-02	GO:0045786	negative regulation of cell cycle
1.46	2.67e-02	GO:0043405	regulation of MAP kinase activity
1.42	2.73e-02	GO:0007507	heart development
1.48	2.79e-02	GO:0016569	covalent chromatin modification
1.29	2.87e-02	GO:0070271	protein complex biogenesis
1.34	3.28e-02	GO:0048598	embryonic morphogenesis
1.43	3.51e-02	GO:0009261	ribonucleotide catabolic process
1.35	3.67e-02	GO:0033043	regulation of organelle organization
1.73	3.77e-02	GO:0031123	RNA 3'-end processing
1.60	4.11e-02	GO:0051028	mRNA transport
1.29	4.13e-02	GO:0006461	protein complex assembly
1.35	4.63e-02	GO:0009259	ribonucleotide metabolic process
1.48	4.64e-02	GO:0016570	histone modification
1.30	4.88e-02	GO:0032583	regulation of gene-specific transcription

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.15	5.02e-79	GO:0044424	intracellular part
1.14	7.52e-77	GO:0005622	intracellular
1.18	1.81e-58	GO:0043231	intracellular membrane-bounded organelle
1.18	1.94e-58	GO:0043227	membrane-bounded organelle
1.16	1.22e-55	GO:0043226	organelle
1.16	1.63e-55	GO:0043229	intracellular organelle
1.17	4.37e-44	GO:0005737	cytoplasm
1.23	4.52e-44	GO:0005634	nucleus
1.41	4.13e-33	GO:0031981	nuclear lumen
1.37	2.81e-32	GO:0044428	nuclear part
1.47	1.03e-30	GO:0005654	nucleoplasm
1.35	4.26e-30	GO:0070013	intracellular organelle lumen
1.19	1.16e-29	GO:0044446	intracellular organelle part
1.33	1.66e-28	GO:0031974	membrane-enclosed lumen
1.19	5.32e-28	GO:0044422	organelle part
1.33	9.40e-28	GO:0043233	organelle lumen
1.16	9.47e-22	GO:0044444	cytoplasmic part
1.05	2.37e-21	GO:0005623	cell
1.05	3.35e-21	GO:0044464	cell part
1.29	8.65e-19	GO:0005829	cytosol
1.51	2.52e-14	GO:0005694	chromosome
1.40	3.90e-11	GO:0044451	nucleoplasm part
1.50	5.81e-11	GO:0044427	chromosomal part
1.16	7.90e-11	GO:0032991	macromolecular complex
1.18	4.06e-10	GO:0043228	non-membrane-bounded organelle
1.18	4.06e-10	GO:0043232	intracellular non-membrane-bounded organelle
1.16	4.17e-08	GO:0043234	protein complex
1.54	3.30e-06	GO:0000785	chromatin
1.52	4.22e-05	GO:0000228	nuclear chromosome
1.18	8.83e-05	GO:0012505	endomembrane system
1.15	1.15e-04	GO:0031090	organelle membrane
1.21	1.27e-03	GO:0005794	Golgi apparatus
1.51	1.44e-03	GO:0044454	nuclear chromosome part
1.41	2.64e-03	GO:0005667	transcription factor complex
1.53	4.66e-03	GO:0000793	condensed chromosome
1.29	4.96e-03	GO:0000139	Golgi membrane
1.27	6.96e-03	GO:0030529	ribonucleoprotein complex
1.80	1.64e-02	GO:0016605	PML body
1.65	1.91e-02	GO:0000790	nuclear chromatin
1.22	2.23e-02	GO:0015630	microtubule cytoskeleton
1.24	2.58e-02	GO:0044431	Golgi apparatus part
1.20	4.04e-02	GO:0031410	cytoplasmic vesicle
1.20	4.19e-02	GO:0031982	vesicle
1.73	4.44e-02	GO:0000123	histone acetyltransferase complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.20	3.46e-50	GO:0005515	protein binding
1.10	1.41e-37	GO:0005488	binding
1.29	6.01e-21	GO:0000166	nucleotide binding
1.29	2.12e-16	GO:0035639	purine ribonucleoside triphosphate binding
1.28	9.84e-16	GO:0032553	ribonucleotide binding
1.28	9.84e-16	GO:0032555	purine ribonucleotide binding
1.28	1.48e-15	GO:0017076	purine nucleotide binding
1.19	7.56e-14	GO:0003676	nucleic acid binding
1.20	1.87e-09	GO:0003677	DNA binding
1.25	6.75e-09	GO:0005524	ATP binding
1.24	1.76e-08	GO:0032559	adenyl ribonucleotide binding
1.24	1.81e-08	GO:0030554	adenyl nucleotide binding
1.30	1.85e-08	GO:0030528	transcription regulator activity
1.11	6.10e-08	GO:0003824	catalytic activity
1.32	1.43e-07	GO:0003723	RNA binding
1.21	2.71e-07	GO:0016740	transferase activity
1.46	7.47e-07	GO:0005525	GTP binding
1.29	8.03e-07	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.44	2.24e-06	GO:0019001	guanyl nucleotide binding
1.44	2.24e-06	GO:0032561	guanyl ribonucleotide binding
1.58	3.98e-06	GO:0003924	GTPase activity
1.26	8.01e-06	GO:0001071	nucleic acid binding transcription factor activity
1.26	8.01e-06	GO:0003700	sequence-specific DNA binding transcription factor activity
1.42	1.36e-05	GO:0003712	transcription cofactor activity
1.41	1.76e-05	GO:0000988	protein binding transcription factor activity
1.41	1.76e-05	GO:0000989	transcription factor binding transcription factor activity
1.29	2.53e-05	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.28	2.65e-05	GO:0016301	kinase activity
1.43	6.99e-05	GO:0016563	transcription activator activity
1.36	1.13e-04	GO:0004674	protein serine/threonine kinase activity
1.44	1.14e-04	GO:0008134	transcription factor binding
1.29	1.53e-04	GO:0043565	sequence-specific DNA binding
1.30	1.91e-04	GO:0004672	protein kinase activity
1.47	5.41e-04	GO:0019787	small conjugating protein ligase activity
1.26	6.58e-04	GO:0019899	enzyme binding
1.34	7.58e-04	GO:0019904	protein domain specific binding
1.76	8.63e-04	GO:0035257	nuclear hormone receptor binding
1.42	1.09e-03	GO:0016881	acid-amino acid ligase activity
1.40	1.13e-03	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.46	1.49e-03	GO:0004842	ubiquitin-protein ligase activity
1.24	1.79e-03	GO:0016462	pyrophosphatase activity
1.24	2.21e-03	GO:0017111	nucleoside-triphosphatase activity
1.24	2.76e-03	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.23	4.21e-03	GO:0016817	hydrolase activity, acting on acid anhydrides
1.66	4.38e-03	GO:0051427	hormone receptor binding
1.51	5.13e-03	GO:0004721	phosphoprotein phosphatase activity
1.53	6.72e-03	GO:0003714	transcription corepressor activity
1.39	1.48e-02	GO:0016791	phosphatase activity
1.66	2.03e-02	GO:0008565	protein transporter activity
2.88	3.83e-02	GO:0008143	poly(A) RNA binding