Motif ID: UUGGCAA

Z-value: 0.516


Mature miRNA associated with seed UUGGCAA:

NamemiRBase Accession
hsa-miR-182 MIMAT0000259



Activity profile for motif UUGGCAA.

activity profile for motif UUGGCAA


Sorted Z-values histogram for motif UUGGCAA

Sorted Z-values for motif UUGGCAA



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGGCAA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_131762017 1.964 NM_001005463
EBF3
early B-cell factor 3
chr9_+_79056581 1.671 NM_001097634
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr9_+_79074067 1.581 NM_001097633
NM_001490
GCNT1

glucosaminyl (N-acetyl) transferase 1, core 2

chr9_+_79093256 1.565 NM_001097635
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr3_+_193853930 1.554 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr9_+_79115548 1.546 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr8_-_22550708 1.530 NM_004430
EGR3
early growth response 3
chr8_-_22549901 1.511 NM_001199880
EGR3
early growth response 3
chr3_+_39851028 1.465 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr8_-_22550057 1.462 NM_001199881
EGR3
early growth response 3
chr9_-_134151905 1.312 NM_033387
FAM78A
family with sequence similarity 78, member A
chr20_+_42544781 1.170 NM_001098796
NM_032883
TOX2

TOX high mobility group box family member 2

chr8_-_80993009 1.165 NM_001025252
TPD52
tumor protein D52
chr8_-_81083660 1.156 NM_001025253
NM_005079
TPD52

tumor protein D52

chr20_+_42543417 1.107 NM_001098797
TOX2
TOX high mobility group box family member 2
chr1_+_82266081 1.099 NM_012302
LPHN2
latrophilin 2
chr20_+_42574535 1.093 NM_001098798
TOX2
TOX high mobility group box family member 2
chr4_-_102268626 1.072 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr17_+_68165660 1.060 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr21_+_18885104 1.055 NM_001207063
NM_001207064
NM_001207065
NM_001207066
NM_001338
CXADR




coxsackie virus and adenovirus receptor




chrX_+_101967103 0.989 NM_001004051
NM_001184874
NM_001184875
NM_001184876
NM_138437
GPRASP2




G protein-coupled receptor associated sorting protein 2




chr12_-_106533810 0.981 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr12_+_32654976 0.956 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr4_+_41362750 0.945 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr1_-_209979388 0.926 NM_001206696
NM_006147
IRF6

interferon regulatory factor 6

chr4_+_41614911 0.923 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr18_-_46475702 0.911 NM_001190822
SMAD7
SMAD family member 7
chr8_+_37654395 0.896 NM_032777
GPR124
G protein-coupled receptor 124
chr7_+_17338182 0.873 NM_001621
AHR
aryl hydrocarbon receptor
chr3_-_168865521 0.869 NM_001164000
MECOM
MDS1 and EVI1 complex locus
chr3_+_37903643 0.860 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr14_+_64682671 0.856 NM_182910
SYNE2
spectrin repeat containing, nuclear envelope 2
chr18_-_46477080 0.851 NM_001190821
NM_005904
SMAD7

SMAD family member 7

chr3_-_168864325 0.847 NM_001105078
MECOM
MDS1 and EVI1 complex locus
chr14_+_64680858 0.846 NM_182913
SYNE2
spectrin repeat containing, nuclear envelope 2
chr3_-_168864066 0.843 NM_001105077
NM_001163999
NM_005241
MECOM


MDS1 and EVI1 complex locus


chr18_-_46469118 0.837 NM_001190823
SMAD7
SMAD family member 7
chr2_+_203499819 0.835 NM_173511
FAM117B
family with sequence similarity 117, member B
chr9_+_115513050 0.833 NM_001012994
SNX30
sorting nexin family member 30
chr9_+_4490193 0.825 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr3_+_43328001 0.771 NM_001100594
NM_017719
SNRK

SNF related kinase

chr9_-_80646150 0.738 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr7_-_86595203 0.737 NM_152748
KIAA1324L
KIAA1324-like
chr12_-_96184510 0.722 NM_021229
NTN4
netrin 4
chr11_-_89322778 0.701 NM_001143837
NOX4
NADPH oxidase 4
chr11_-_2906960 0.692 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr2_-_44588622 0.685 NM_001171606
NM_001171613
PREPL

prolyl endopeptidase-like

chr9_-_111882209 0.667 NM_032012
C9orf5
chromosome 9 open reading frame 5
chr2_+_109150807 0.665 NM_001193483
LIMS1
LIM and senescent cell antigen-like domains 1
chr16_+_14164879 0.664 NM_014048
MKL2
MKL/myocardin-like 2
chr2_+_109237679 0.664 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_46524448 0.662 NM_001430
EPAS1
endothelial PAS domain protein 1
chr11_-_89224413 0.647 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr17_+_47865980 0.637 NM_001199155
NM_001199156
NM_001199157
NM_001199158
NM_007067
KAT7




K(lysine) acetyltransferase 7




chr2_+_235860616 0.637 NM_014521
SH3BP4
SH3-domain binding protein 4
chr12_-_56727720 0.627 NM_001166279
NM_014871
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr5_-_90679115 0.622 NM_020801
ARRDC3
arrestin domain containing 3
chrX_+_77166178 0.622 NM_000052
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr12_+_3186520 0.618 NM_001168320
NM_006675
TSPAN9

tetraspanin 9

chr13_-_107187312 0.617 NM_004093
EFNB2
ephrin-B2
chr6_+_11538486 0.609 NM_001100829
TMEM170B
transmembrane protein 170B
chr7_-_86688944 0.602 NM_001142749
KIAA1324L
KIAA1324-like
chr13_+_39612440 0.601 NM_001012754
NM_001017370
NHLRC3

NHL repeat containing 3

chr2_-_44587812 0.599 NM_006036
PREPL
prolyl endopeptidase-like
chr8_-_52811707 0.594 NM_052937
PCMTD1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr8_-_81787015 0.590 NM_001033723
ZNF704
zinc finger protein 704
chr2_+_45878912 0.585 NM_005400
PRKCE
protein kinase C, epsilon
chr2_+_109204745 0.582 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_-_44588943 0.581 NM_001171603
NM_001171617
PREPL

prolyl endopeptidase-like

chr2_+_109271267 0.577 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chrX_-_154033729 0.576 NM_001166460
NM_001166461
NM_001166462
NM_002436
MPP1



membrane protein, palmitoylated 1, 55kDa



chr12_-_56727446 0.572 NM_001127460
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr2_-_44586854 0.570 NM_001042385
NM_001042386
PREPL

prolyl endopeptidase-like

chr4_-_42658883 0.568 NM_001105529
NM_006095
ATP8A1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr7_+_89840999 0.563 NM_001244944
NM_001244945
NM_152999
NM_001040665
NM_001244946
STEAP2




STEAP family member 2, metalloreductase




chr15_-_56035176 0.560 NM_173814
PRTG
protogenin
chr2_+_109223600 0.559 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr3_-_32023237 0.557 NM_001174060
NM_017784
OSBPL10

oxysterol binding protein-like 10

chr14_+_24867926 0.557 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr3_+_194406614 0.555 NM_153690
FAM43A
family with sequence similarity 43, member A
chr1_+_25870043 0.549 NM_015627
LDLRAP1
low density lipoprotein receptor adaptor protein 1
chr14_-_54955714 0.543 NM_004124
GMFB
glia maturation factor, beta
chr4_+_140586921 0.538 NM_001204366
NM_001204367
NM_001204368
NM_002413
MGST2



microsomal glutathione S-transferase 2



chr17_+_34136437 0.534 NM_003487
NM_139215
TAF15

TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa

chr6_+_136172802 0.534 NM_018945
PDE7B
phosphodiesterase 7B
chr14_-_89883306 0.532 NM_005197
FOXN3
forkhead box N3
chr5_-_107006585 0.531 NM_001962
EFNA5
ephrin-A5
chr11_+_111848008 0.522 NM_033425
DIXDC1
DIX domain containing 1
chr1_+_178694273 0.515 NM_152663
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr1_-_94703252 0.514 NM_004815
ARHGAP29
Rho GTPase activating protein 29
chr3_-_169381417 0.511 NM_001205194
NM_004991
MECOM

MDS1 and EVI1 complex locus

chr19_+_10736167 0.508 NM_020428
SLC44A2
solute carrier family 44, member 2
chr9_+_91003238 0.504 NM_006717
SPIN1
spindlin 1
chr19_+_10713055 0.499 NM_001145056
SLC44A2
solute carrier family 44, member 2
chr19_-_14316980 0.493 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr1_-_76076762 0.491 NM_001130058
NM_152697
SLC44A5

solute carrier family 44, member 5

chr2_+_109204904 0.489 NM_001193488
LIMS1
LIM and senescent cell antigen-like domains 1
chr14_+_58765209 0.483 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr1_+_76540374 0.476 NM_001160011
NM_152996
ST6GALNAC3

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

chr11_-_27681195 0.466 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr6_-_41909386 0.459 NM_001136125
NM_001760
CCND3

cyclin D3

chr14_-_90085325 0.458 NM_001085471
FOXN3
forkhead box N3
chr19_+_32897021 0.457 NM_207325
DPY19L3
dpy-19-like 3 (C. elegans)
chr19_+_39897457 0.455 NM_003407
ZFP36
zinc finger protein 36, C3H type, homolog (mouse)
chr3_-_27763784 0.445 NM_005442
EOMES
eomesodermin
chr2_-_55646946 0.436 NM_001135597
NM_018084
CCDC88A

coiled-coil domain containing 88A

chr19_+_32896515 0.436 NM_001172774
DPY19L3
dpy-19-like 3 (C. elegans)
chr10_-_116286661 0.434 NM_006720
ABLIM1
actin binding LIM protein 1
chr8_+_97505876 0.429 NM_002998
SDC2
syndecan 2
chr6_-_42016609 0.429 NM_001136017
NM_001136126
CCND3

cyclin D3

chr6_-_79787939 0.427 NM_017934
PHIP
pleckstrin homology domain interacting protein
chr12_+_56521953 0.420 NM_001184796
NM_015292
ESYT1

extended synaptotagmin-like protein 1

chr10_-_116418056 0.420 NM_002313
ABLIM1
actin binding LIM protein 1
chr10_+_129705299 0.418 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr14_+_66974124 0.412 NM_001024218
NM_020806
GPHN

gephyrin

chr10_-_116444374 0.410 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr11_+_92085261 0.404 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr3_+_23987514 0.401 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr12_-_31743822 0.400 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr7_+_30174343 0.398 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr1_+_198125890 0.397 NM_133494
NEK7
NIMA (never in mitosis gene a)-related kinase 7
chr2_-_218808705 0.396 NM_022648
TNS1
tensin 1
chr21_-_39870303 0.389 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr6_-_16761600 0.389 NM_000332
NM_001128164
ATXN1

ataxin 1

chr1_+_212208918 0.387 NM_016448
DTL
denticleless homolog (Drosophila)
chr9_+_2621740 0.381 NM_001018056
NM_003383
VLDLR

very low density lipoprotein receptor

chr8_-_95961543 0.381 NM_001135733
NM_033285
TP53INP1

tumor protein p53 inducible nuclear protein 1

chr9_-_16870719 0.379 NM_017637
BNC2
basonuclin 2
chr1_-_236228476 0.378 NM_002508
NID1
nidogen 1
chr17_-_80656461 0.377 NM_006822
RAB40B
RAB40B, member RAS oncogene family
chr4_-_89744154 0.375 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr5_+_86564044 0.375 NM_002890
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr21_-_40033617 0.373 NM_001243432
NM_001136154
NM_004449
ERG


v-ets erythroblastosis virus E26 oncogene homolog (avian)


chr3_-_66024508 0.371 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr5_+_86564727 0.367 NM_022650
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr11_-_27721975 0.367 NM_001143813
NM_001143814
NM_001709
BDNF


brain-derived neurotrophic factor


chr10_+_35535952 0.364 NM_181698
CCNY
cyclin Y
chr18_-_72921280 0.363 NM_175907
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr14_+_63671101 0.356 NM_020663
RHOJ
ras homolog gene family, member J
chr8_-_93978264 0.356 NM_001191035
NM_001171795
NM_001171796
NM_001171797
NM_001171798
NM_001171799
C8orf83





chromosome 8 open reading frame 83





chr1_+_84764048 0.355 NM_001010971
SAMD13
sterile alpha motif domain containing 13
chr1_+_84768333 0.354 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr1_+_84767288 0.353 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr11_-_27722446 0.347 NM_001143812
BDNF
brain-derived neurotrophic factor
chr6_+_150070818 0.346 NM_001252049
NM_001252050
NM_001252051
NM_001252052
NM_001252053
NM_005389
PCMT1





protein-L-isoaspartate (D-aspartate) O-methyltransferase





chrX_-_114468604 0.346 NM_001243963
NM_020871
LRCH2

leucine-rich repeats and calponin homology (CH) domain containing 2

chr2_-_158731622 0.345 NM_001105
ACVR1
activin A receptor, type I
chr9_+_36036900 0.343 NM_021111
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr11_-_27722599 0.343 NM_001143808
NM_001143809
NM_001143810
NM_001143811
BDNF



brain-derived neurotrophic factor



chr11_-_27721179 0.340 NM_170734
BDNF
brain-derived neurotrophic factor
chr1_+_84609941 0.340 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr8_-_93977715 0.339 NM_001191036
C8orf83
chromosome 8 open reading frame 83
chr10_+_129845806 0.339 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr11_-_27742224 0.338 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr6_+_17600504 0.337 NM_016255
FAM8A1
family with sequence similarity 8, member A1
chr1_+_84630575 0.336 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr8_-_9008138 0.335 NM_024607
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr1_+_84630014 0.333 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr6_-_32157511 0.333 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chrX_-_34675366 0.327 NM_031442
TMEM47
transmembrane protein 47
chr17_+_61699786 0.325 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr1_-_109935869 0.324 NM_001205228
SORT1
sortilin 1
chr11_-_27723061 0.320 NM_170733
BDNF
brain-derived neurotrophic factor
chr9_-_79520878 0.319 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr1_+_164528586 0.313 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr10_-_101945787 0.311 NM_001100626
ERLIN1
ER lipid raft associated 1
chr6_+_88182624 0.311 NM_001168398
NM_006416
SLC35A1

solute carrier family 35 (CMP-sialic acid transporter), member A1

chr3_+_135684463 0.309 NM_001190447
NM_002718
PPP2R3A

protein phosphatase 2, regulatory subunit B'', alpha

chr11_-_27743604 0.309 NM_170731
BDNF
brain-derived neurotrophic factor
chr10_-_101945686 0.308 NM_006459
ERLIN1
ER lipid raft associated 1
chr5_+_118407067 0.308 NM_005509
DMXL1
Dmx-like 1
chr1_+_84647342 0.306 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr7_+_142985307 0.306 NM_032982
NM_032983
CASP2

caspase 2, apoptosis-related cysteine peptidase

chr3_-_64211111 0.306 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr10_+_35625608 0.305 NM_145012
CCNY
cyclin Y
chr2_-_62733475 0.303 NM_198276
TMEM17
transmembrane protein 17
chr11_-_27741192 0.303 NM_001143807
BDNF
brain-derived neurotrophic factor
chr3_+_135741576 0.302 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr21_-_44846927 0.300 NM_173354
SIK1
salt-inducible kinase 1
chr22_-_36903086 0.300 NM_024955
NM_001102371
FOXRED2

FAD-dependent oxidoreductase domain containing 2

chr10_-_65225605 0.299 NM_032776
JMJD1C
jumonji domain containing 1C
chr8_-_9009050 0.299 NM_001201329
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr2_+_61292999 0.293 NM_001129993
KIAA1841
KIAA1841
chr1_+_33004771 0.289 NM_001040441
ZBTB8A
zinc finger and BTB domain containing 8A
chr8_-_103137134 0.289 NM_001040630
NCALD
neurocalcin delta
chr1_-_92371558 0.288 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr2_+_241375030 0.287 NM_002081
GPC1
glypican 1
chr7_-_112579726 0.281 NM_152556
C7orf60
chromosome 7 open reading frame 60
chr8_-_102803438 0.280 NM_032041
NCALD
neurocalcin delta
chr16_+_69220940 0.278 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr22_-_39548448 0.277 NM_175709
CBX7
chromobox homolog 7
chr1_-_92351613 0.274 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr1_-_8483701 0.272 NM_001042682
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr18_-_812268 0.271 NM_005433
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr10_-_62703822 0.271 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr3_+_23986735 0.271 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr1_+_201798281 0.270 NM_018085
IPO9
importin 9
chr2_+_121010413 0.270 NM_002881
RALB
v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)
chr20_-_60640842 0.269 NM_003185
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr11_+_7535000 0.268 NM_003621
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.74 5.84e-06 GO:0006464 protein modification process
1.67 5.69e-05 GO:0043412 macromolecule modification
1.36 7.47e-03 GO:0023052 signaling
1.78 9.54e-03 GO:0006793 phosphorus metabolic process
1.78 9.54e-03 GO:0006796 phosphate metabolic process
1.46 1.02e-02 GO:0044267 cellular protein metabolic process
1.13 1.05e-02 GO:0009987 cellular process
1.90 1.99e-02 GO:0006468 protein phosphorylation
1.63 2.75e-02 GO:0035556 intracellular signal transduction
1.34 4.87e-02 GO:0007275 multicellular organismal development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.44 3.59e-02 GO:0016323 basolateral plasma membrane

Nothing significant found in function category.