Motif ID: UUGUUCG

Z-value: 0.579


Mature miRNA associated with seed UUGUUCG:

NamemiRBase Accession
hsa-miR-375 MIMAT0000728



Activity profile for motif UUGUUCG.

activity profile for motif UUGUUCG


Sorted Z-values histogram for motif UUGUUCG

Sorted Z-values for motif UUGUUCG



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGUUCG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_79086087 0.728 NM_006820
IFI44L
interferon-induced protein 44-like
chr4_-_79860369 0.439 NM_001040202
PAQR3
progestin and adipoQ receptor family member III
chr7_-_102715014 0.359 NM_145032
FBXL13
F-box and leucine-rich repeat protein 13
chr7_-_102715171 0.353 NM_001111038
FBXL13
F-box and leucine-rich repeat protein 13
chr11_-_86666211 0.347 NM_012193
FZD4
frizzled family receptor 4
chr5_-_59189620 0.341 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58295758 0.325 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58334936 0.318 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr1_+_162466963 0.303 NM_001184763
UHMK1
U2AF homology motif (UHM) kinase 1
chr1_+_162467594 0.295 NM_144624
NM_175866
UHMK1

U2AF homology motif (UHM) kinase 1

chr5_-_59783885 0.291 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_-_27183225 0.277 NM_019102
HOXA5
homeobox A5
chr5_-_58571916 0.268 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr17_+_5031686 0.257 NM_004505
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr5_-_58652671 0.250 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_-_27159213 0.245 NM_030661
HOXA3
homeobox A3
chr8_-_94753211 0.241 NM_203390
RBM12B
RNA binding motif protein 12B
chr12_-_89919182 0.239 NM_001199777
POC1B
POC1 centriolar protein homolog B (Chlamydomonas)
chr7_-_27166638 0.239 NM_153631
HOXA3
homeobox A3
chr5_-_59064437 0.237 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_-_151329153 0.236 NM_024429
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr1_+_111682832 0.236 NM_006090
CEPT1
choline/ethanolamine phosphotransferase 1
chr3_-_192635933 0.235 NM_178496
MB21D2
Mab-21 domain containing 2
chr3_+_23244703 0.232 NM_152653
UBE2E2
ubiquitin-conjugating enzyme E2E 2
chr15_+_39542884 0.232 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr10_-_35930357 0.232 NM_031866
FZD8
frizzled family receptor 8
chr5_-_58882274 0.229 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_+_184020343 0.224 NM_024949
WWC2
WW and C2 domain containing 2
chrX_-_19988381 0.220 NM_198279
CXorf23
chromosome X open reading frame 23
chr1_+_65613211 0.220 NM_203464
NM_001005353
AK4

adenylate kinase 4

chr1_+_65613771 0.218 NM_013410
AK4
adenylate kinase 4
chr14_+_38677186 0.212 NM_001049
SSTR1
somatostatin receptor 1
chr12_-_57472573 0.209 NM_001130963
NM_015257
TMEM194A

transmembrane protein 194A

chr7_+_107204402 0.207 NM_181581
DUS4L
dihydrouridine synthase 4-like (S. cerevisiae)
chr4_-_157892545 0.203 NM_016205
PDGFC
platelet derived growth factor C
chr17_-_49198084 0.199 NM_001130527
NM_001130528
NM_003971
SPAG9


sperm associated antigen 9


chr7_-_47621741 0.198 NM_022748
TNS3
tensin 3
chr10_+_114135013 0.198 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_+_169075869 0.196 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr10_+_114133838 0.195 NM_203379
ACSL5
acyl-CoA synthetase long-chain family member 5
chr17_-_58469577 0.193 NM_032582
USP32
ubiquitin specific peptidase 32
chr15_-_91475653 0.193 NM_198527
HDDC3
HD domain containing 3
chr7_-_151511925 0.191 NM_001040633
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr6_+_71123105 0.190 NM_001105531
NM_020819
FAM135A

family with sequence similarity 135, member A

chr2_+_7017795 0.189 NM_080657
RSAD2
radical S-adenosyl methionine domain containing 2
chr7_-_151574209 0.187 NM_016203
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr4_+_95679075 0.187 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr16_+_77822400 0.182 NM_020927
VAT1L
vesicle amine transport protein 1 homolog (T. californica)-like
chr1_+_15853348 0.182 NM_015291
DNAJC16
DnaJ (Hsp40) homolog, subfamily C, member 16
chr12_-_76742165 0.182 NM_024685
BBS10
Bardet-Biedl syndrome 10
chr2_+_223725675 0.181 NM_004457
NM_203372
ACSL3

acyl-CoA synthetase long-chain family member 3

chr21_-_36421586 0.180 NM_001754
RUNX1
runt-related transcription factor 1
chr10_+_114135937 0.180 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr9_+_71394919 0.178 NM_138333
FAM122A
family with sequence similarity 122A
chr5_+_149109814 0.177 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr18_-_57026465 0.176 NM_005570
LMAN1
lectin, mannose-binding, 1
chr4_+_78978723 0.175 NM_001166133
NM_025074
FRAS1

Fraser syndrome 1

chr7_-_559479 0.173 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr3_-_135914654 0.172 NM_018133
MSL2
male-specific lethal 2 homolog (Drosophila)
chr9_+_4985243 0.169 NM_004972
JAK2
Janus kinase 2
chr1_+_244515936 0.169 NM_001012970
C1orf100
chromosome 1 open reading frame 100
chr3_-_178789597 0.169 NM_022470
NM_152240
ZMAT3

zinc finger, matrin-type 3

chr17_+_54671059 0.165 NM_005450
NOG
noggin
chr3_-_45883562 0.158 NM_020347
LZTFL1
leucine zipper transcription factor-like 1
chr1_+_111682248 0.157 NM_001007794
CEPT1
choline/ethanolamine phosphotransferase 1
chr1_-_236445294 0.154 NM_019891
ERO1LB
ERO1-like beta (S. cerevisiae)
chr17_-_3496122 0.153 NM_080706
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr20_-_13765509 0.151 NM_016649
ESF1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr5_+_149151502 0.150 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr6_+_71136141 0.147 NM_001162529
FAM135A
family with sequence similarity 135, member A
chr14_-_95623665 0.146 NM_177438
DICER1
dicer 1, ribonuclease type III
chr3_-_160822625 0.146 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr16_+_66914380 0.145 NM_020786
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr7_-_92747317 0.144 NM_001193307
NM_017654
SAMD9

sterile alpha motif domain containing 9

chr15_+_78730477 0.143 NM_004136
IREB2
iron-responsive element binding protein 2
chr22_-_45404785 0.143 NM_001242450
PHF21B
PHD finger protein 21B
chr3_-_135913276 0.143 NM_001145417
MSL2
male-specific lethal 2 homolog (Drosophila)
chr4_+_86396251 0.143 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr3_-_151047309 0.142 NM_176894
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr20_+_58515408 0.141 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr14_+_31028328 0.140 NM_017769
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr8_-_57123858 0.138 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr6_-_119252887 0.138 NM_017696
MCM9
minichromosome maintenance complex component 9
chr10_+_16478941 0.137 NM_001001484
NM_030664
PTER

phosphotriesterase related

chr18_+_54318561 0.136 NM_015285
NM_052834
WDR7

WD repeat domain 7

chr17_+_55163077 0.135 NM_001242903
NM_001242902
AKAP1

A kinase (PRKA) anchor protein 1

chr7_+_12250818 0.134 NM_001134232
NM_018374
TMEM106B

transmembrane protein 106B

chr12_+_53774422 0.133 NM_003109
SP1
Sp1 transcription factor
chr14_-_95599794 0.133 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr4_+_86851425 0.132 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chr12_+_53773924 0.130 NM_001251825
NM_138473
SP1

Sp1 transcription factor

chr17_-_6554842 0.130 NM_016060
MED31
mediator complex subunit 31
chr11_+_93474717 0.130 NM_014039
C11orf54
chromosome 11 open reading frame 54
chr17_+_30813928 0.130 NM_003885
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr20_+_58508818 0.130 NM_001190826
C20orf177
chromosome 20 open reading frame 177
chr14_+_32047121 0.127 NM_001201573
NUBPL
nucleotide binding protein-like
chr22_+_40440664 0.127 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr2_-_21266915 0.126 NM_000384
APOB
apolipoprotein B (including Ag(x) antigen)
chr12_-_26985922 0.125 NM_002223
ITPR2
inositol 1,4,5-trisphosphate receptor, type 2
chr22_-_45405429 0.124 NM_138415
PHF21B
PHD finger protein 21B
chr2_-_68384575 0.123 NM_138458
WDR92
WD repeat domain 92
chr17_-_46651809 0.122 NM_002146
HOXB3
homeobox B3
chr12_-_51717905 0.122 NM_016293
BIN2
bridging integrator 2
chr15_+_81071708 0.122 NM_018689
KIAA1199
KIAA1199
chr17_+_55162530 0.121 NM_003488
AKAP1
A kinase (PRKA) anchor protein 1
chrX_-_108976509 0.120 NM_004458
NM_022977
ACSL4

acyl-CoA synthetase long-chain family member 4

chr22_-_42017032 0.120 NM_015704
PPPDE2
PPPDE peptidase domain containing 2
chr7_-_32534869 0.120 NM_001130710
NM_001139499
LSM5

LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)

chr2_-_74405800 0.120 NM_018221
MOB1A
MOB kinase activator 1A
chr4_+_48343502 0.120 NM_020846
SLAIN2
SLAIN motif family, member 2
chr22_-_45405780 0.119 NM_001135862
PHF21B
PHD finger protein 21B
chr16_-_12897693 0.118 NM_001099455
NM_018340
CPPED1

calcineurin-like phosphoesterase domain containing 1

chr7_+_26241281 0.117 NM_016587
CBX3
chromobox homolog 3
chr5_-_145562235 0.117 NM_020117
LARS
leucyl-tRNA synthetase
chr7_+_26240830 0.117 NM_007276
CBX3
chromobox homolog 3
chr6_-_105584982 0.116 NM_001199563
BVES
blood vessel epicardial substance
chr3_-_114866090 0.116 NM_015642
ZBTB20
zinc finger and BTB domain containing 20
chr12_+_1100352 0.116 NM_178039
NM_178040
ERC1

ELKS/RAB6-interacting/CAST family member 1

chr17_+_48450579 0.114 NM_001166131
NM_152463
EME1

essential meiotic endonuclease 1 homolog 1 (S. pombe)

chr4_+_113152838 0.114 NM_001128426
NM_018569
AP1AR

adaptor-related protein complex 1 associated regulatory protein

chr14_-_39572414 0.114 NM_006364
SEC23A
Sec23 homolog A (S. cerevisiae)
chr8_+_38034066 0.112 NM_001204878
NM_004874
BAG4

BCL2-associated athanogene 4

chr12_-_131002409 0.111 NM_015347
RIMBP2
RIMS binding protein 2
chr9_-_100954883 0.110 NM_052820
CORO2A
coronin, actin binding protein, 2A
chr5_-_40798263 0.110 NM_006251
NM_206907
PRKAA1

protein kinase, AMP-activated, alpha 1 catalytic subunit

chr5_-_136834887 0.110 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr17_-_3500335 0.109 NM_018727
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr1_+_62902325 0.109 NM_003368
USP1
ubiquitin specific peptidase 1
chr14_+_32183774 0.108 NM_001201574
NUBPL
nucleotide binding protein-like
chr8_+_67687415 0.108 NM_013257
NM_170709
SGK3

serum/glucocorticoid regulated kinase family, member 3

chr9_+_115983807 0.108 NM_001859
SLC31A1
solute carrier family 31 (copper transporters), member 1
chr12_+_38710556 0.108 NM_001013620
ALG10B
asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast)
chr4_-_153601085 0.107 NM_152680
TMEM154
transmembrane protein 154
chr8_-_92053043 0.107 NM_018710
TMEM55A
transmembrane protein 55A
chr3_+_156008775 0.107 NM_172159
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr14_+_32030579 0.107 NM_025152
NUBPL
nucleotide binding protein-like
chr15_+_50716568 0.106 NM_001128610
NM_001128611
NM_005154
USP8


ubiquitin specific peptidase 8


chr19_-_38146288 0.106 NM_014898
ZFP30
zinc finger protein 30 homolog (mouse)
chr1_-_167523016 0.105 NM_003851
CREG1
cellular repressor of E1A-stimulated genes 1
chr12_+_4382882 0.105 NM_001759
CCND2
cyclin D2
chr3_+_88198892 0.105 NM_173824
C3orf38
chromosome 3 open reading frame 38
chr8_-_65711104 0.104 NM_004820
CYP7B1
cytochrome P450, family 7, subfamily B, polypeptide 1
chr11_+_131240370 0.104 NM_001048209
NTM
neurotrimin
chr5_+_89770680 0.104 NM_006467
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr6_-_166796459 0.103 NM_016098
BRP44L
brain protein 44-like
chr12_-_39299335 0.103 NM_153634
CPNE8
copine VIII
chr6_+_117996616 0.102 NM_138459
NUS1
nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
chr13_+_77566043 0.102 NM_006493
CLN5
ceroid-lipofuscinosis, neuronal 5
chr6_+_119215240 0.101 NM_014034
ASF1A
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr6_+_17600504 0.101 NM_016255
FAM8A1
family with sequence similarity 8, member A1
chr17_-_5342424 0.101 NM_001212
C1QBP
complement component 1, q subcomponent binding protein
chr2_-_198650937 0.101 NM_197970
BOLL
bol, boule-like (Drosophila)
chr17_-_3499124 0.100 NM_080705
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr5_-_156772672 0.099 NM_001001343
FNDC9
fibronectin type III domain containing 9
chr1_+_2160133 0.099 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr4_+_86699846 0.099 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr11_+_131780537 0.099 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr3_+_63884074 0.099 NM_001177387
ATXN7
ataxin 7
chr1_-_67896098 0.098 NM_001018067
NM_001018068
NM_001018069
NM_015640
SERBP1



SERPINE1 mRNA binding protein 1



chr1_-_62785067 0.098 NM_181712
KANK4
KN motif and ankyrin repeat domains 4
chr4_-_125633716 0.098 NM_001167882
NM_020337
ANKRD50

ankyrin repeat domain 50

chr3_-_97691219 0.097 NM_001042533
NM_032778
NM_153182
MINA


MYC induced nuclear antigen


chr3_+_196295708 0.096 NM_001105573
FBXO45
F-box protein 45
chr3_-_160117314 0.096 NM_001190241
NM_020800
IFT80

intraflagellar transport 80 homolog (Chlamydomonas)

chr3_+_113775580 0.096 NM_024638
QTRTD1
queuine tRNA-ribosyltransferase domain containing 1
chr8_+_67624652 0.096 NM_001033578
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr7_-_128695181 0.094 NM_001191028
NM_012470
TNPO3

transportin 3

chr17_-_58603492 0.094 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr13_+_20532788 0.094 NM_003453
NM_197968
NM_001190964
ZMYM2


zinc finger, MYM-type 2


chr6_-_105584220 0.094 NM_147147
BVES
blood vessel epicardial substance
chr3_+_63953419 0.094 NM_001128149
ATXN7
ataxin 7
chr11_+_111944967 0.094 NM_001082969
NM_001082970
NM_018195
C11orf57


chromosome 11 open reading frame 57


chr5_+_40909558 0.093 NM_000587
C7
complement component 7
chr1_+_110082493 0.093 NM_031936
GPR61
G protein-coupled receptor 61
chr7_-_131241321 0.093 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr20_+_43514340 0.093 NM_003404
NM_139323
YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

chr11_-_105892908 0.092 NM_032424
KIAA1826
KIAA1826
chr1_+_78354199 0.092 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr2_+_46769821 0.092 NM_012249
RHOQ
ras homolog gene family, member Q
chr14_-_31926597 0.091 NM_080664
C14orf126
chromosome 14 open reading frame 126
chr5_+_96038492 0.091 NM_173060
CAST
calpastatin
chr10_-_52383611 0.091 NM_147156
SGMS1
sphingomyelin synthase 1
chr7_-_32529972 0.090 NM_012322
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr6_+_163835668 0.090 NM_006775
NM_206853
NM_206854
NM_206855
QKI



QKI, KH domain containing, RNA binding



chr5_+_134240752 0.090 NM_032151
PCBD2
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr1_-_155881163 0.090 NM_006912
RIT1
Ras-like without CAAX 1
chr15_+_74610881 0.090 NM_182791
CCDC33
coiled-coil domain containing 33
chr5_-_90679115 0.089 NM_020801
ARRDC3
arrestin domain containing 3
chr15_+_38544966 0.089 NM_152594
SPRED1
sprouty-related, EVH1 domain containing 1
chr3_+_152017193 0.089 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr11_-_118047336 0.089 NM_004588
SCN2B
sodium channel, voltage-gated, type II, beta
chr6_-_143771788 0.089 NM_182503
ADAT2
adenosine deaminase, tRNA-specific 2
chr3_+_140660639 0.088 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr8_-_101963353 0.088 NM_001135700
NM_001135701
YWHAZ

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

chr1_+_210001267 0.088 NM_014388
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr1_-_21503352 0.088 NM_001198801
NM_001198802
EIF4G3

eukaryotic translation initiation factor 4 gamma, 3

chr10_-_69835042 0.087 NM_015601
NM_022079
HERC4

hect domain and RLD 4

chr3_-_128369710 0.087 NM_002950
RPN1
ribophorin I
chr14_-_30396811 0.086 NM_002742
PRKD1
protein kinase D1
chr15_+_68346571 0.086 NM_016166
PIAS1
protein inhibitor of activated STAT, 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.62 8.11e-05 GO:0031326 regulation of cellular biosynthetic process
1.62 8.14e-05 GO:0009889 regulation of biosynthetic process
1.44 9.25e-05 GO:0044260 cellular macromolecule metabolic process
1.78 1.00e-04 GO:0006464 protein modification process
1.75 1.42e-04 GO:0043412 macromolecule modification
1.48 6.88e-04 GO:0031323 regulation of cellular metabolic process
1.48 8.74e-04 GO:0080090 regulation of primary metabolic process
1.60 1.29e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.48 1.72e-03 GO:0060255 regulation of macromolecule metabolic process
1.57 2.51e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.77 2.59e-03 GO:0009653 anatomical structure morphogenesis
1.56 3.65e-03 GO:0044267 cellular protein metabolic process
1.34 9.40e-03 GO:0043170 macromolecule metabolic process
1.39 1.03e-02 GO:0019222 regulation of metabolic process
1.43 1.31e-02 GO:0007275 multicellular organismal development
1.72 1.35e-02 GO:0007399 nervous system development
1.40 1.70e-02 GO:0032502 developmental process
2.65 1.84e-02 GO:0070647 protein modification by small protein conjugation or removal
1.49 2.80e-02 GO:0010468 regulation of gene expression
2.06 3.34e-02 GO:0009790 embryo development
2.49 3.64e-02 GO:0009792 embryo development ending in birth or egg hatching
1.26 4.29e-02 GO:0044237 cellular metabolic process
1.83 4.47e-02 GO:0032268 regulation of cellular protein metabolic process
3.34 4.60e-02 GO:0006417 regulation of translation
32.92 4.75e-02 GO:0021563 glossopharyngeal nerve development
32.92 4.75e-02 GO:0021615 glossopharyngeal nerve morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 2.35e-06 GO:0043231 intracellular membrane-bounded organelle
1.26 2.72e-06 GO:0043227 membrane-bounded organelle
1.21 6.92e-05 GO:0043229 intracellular organelle
1.20 8.68e-05 GO:0043226 organelle
1.34 1.33e-04 GO:0005634 nucleus
1.16 1.85e-04 GO:0044424 intracellular part
1.14 1.16e-03 GO:0005622 intracellular
1.53 5.44e-03 GO:0044428 nuclear part
1.49 1.44e-02 GO:0070013 intracellular organelle lumen
1.27 1.54e-02 GO:0044446 intracellular organelle part
1.47 2.11e-02 GO:0031974 membrane-enclosed lumen
1.54 2.43e-02 GO:0031981 nuclear lumen
1.26 2.65e-02 GO:0044422 organelle part
1.46 3.03e-02 GO:0043233 organelle lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 2.92e-05 GO:0005488 binding
1.23 7.24e-03 GO:0005515 protein binding
1.48 1.82e-02 GO:0000166 nucleotide binding
1.77 2.41e-02 GO:0030528 transcription regulator activity
1.91 2.43e-02 GO:0019899 enzyme binding