Motif ID: UUUUUGC

Z-value: 2.155


Mature miRNA associated with seed UUUUUGC:

NamemiRBase Accession
hsa-miR-129-5p MIMAT0000242



Activity profile for motif UUUUUGC.

activity profile for motif UUUUUGC


Sorted Z-values histogram for motif UUUUUGC

Sorted Z-values for motif UUUUUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of UUUUUGC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_6659155 2.320 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr1_+_79086087 2.161 NM_006820
IFI44L
interferon-induced protein 44-like
chr1_-_184943673 1.961 NM_052966
FAM129A
family with sequence similarity 129, member A
chr1_-_100715388 1.838 NM_001918
DBT
dihydrolipoamide branched chain transacylase E2
chr3_-_141944441 1.701 NM_001039547
GK5
glycerol kinase 5 (putative)
chr7_-_16460946 1.652 NM_001101417
NM_001101426
ISPD

isoprenoid synthase domain containing

chr7_-_92747317 1.617 NM_001193307
NM_017654
SAMD9

sterile alpha motif domain containing 9

chr9_+_109625347 1.587 NM_021224
ZNF462
zinc finger protein 462
chr22_-_39052579 1.575 NM_001013647
LOC646851
putative uncharacterized protein LOC388900
chr3_+_29322802 1.527 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr1_-_11866079 1.502 NM_005957
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr19_-_53238290 1.479 NM_001161501
NM_001161499
NM_001161500
ZNF611


zinc finger protein 611


chr17_-_1733083 1.443 NM_052928
SMYD4
SET and MYND domain containing 4
chr9_+_74526369 1.432 NM_182505
C9orf85
chromosome 9 open reading frame 85
chr16_+_66914380 1.388 NM_020786
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr1_-_160001723 1.385 NM_145167
PIGM
phosphatidylinositol glycan anchor biosynthesis, class M
chr20_+_58515408 1.322 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr19_-_53233134 1.316 NM_030972
ZNF611
zinc finger protein 611
chr7_+_87505543 1.290 NM_006716
DBF4
DBF4 homolog (S. cerevisiae)
chr4_-_166034003 1.281 NM_001100389
TMEM192
transmembrane protein 192
chr1_-_205091137 1.250 NM_001193272
NM_001193273
NM_005057
RBBP5


retinoblastoma binding protein 5


chr20_+_58508818 1.238 NM_001190826
C20orf177
chromosome 20 open reading frame 177
chr10_+_91092238 1.234 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr6_+_99968851 1.219 NM_001195131
LOC100130890
uncharacterized LOC100130890
chr12_+_121570630 1.217 NM_002562
P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
chr19_-_20150013 1.173 NM_001077349
ZNF682
zinc finger protein 682
chr10_-_113943467 1.171 NM_001244949
NM_020918
GPAM

glycerol-3-phosphate acyltransferase, mitochondrial

chr3_+_121286777 1.147 NM_001012659
ARGFX
arginine-fifty homeobox
chr1_-_150738292 1.144 NM_001199739
NM_004079
CTSS

cathepsin S

chr1_+_53662100 1.142 NM_000098
CPT2
carnitine palmitoyltransferase 2
chr5_+_125936606 1.141 NM_032177
PHAX
phosphorylated adaptor for RNA export
chr10_+_91087601 1.135 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr19_-_53394598 1.122 NM_207333
ZNF320
zinc finger protein 320
chr2_-_208890207 1.114 NM_001080475
PLEKHM3
pleckstrin homology domain containing, family M, member 3
chr19_-_39368889 1.100 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr12_-_116714910 1.099 NM_015335
MED13L
mediator complex subunit 13-like
chr19_-_20150251 1.058 NM_033196
ZNF682
zinc finger protein 682
chr9_-_86571652 1.057 NM_032307
C9orf64
chromosome 9 open reading frame 64
chr10_-_15210610 1.045 NM_004808
NMT2
N-myristoyltransferase 2
chrX_-_109683457 1.029 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr7_+_92076762 1.027 NM_021167
GATAD1
GATA zinc finger domain containing 1
chr12_-_132628841 1.021 NM_175066
DDX51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr3_-_132441302 1.005 NM_153240
NPHP3-ACAD11
NPHP3
NPHP3-ACAD11 readthrough
nephronophthisis 3 (adolescent)
chr9_+_37800779 1.005 NM_024345
DCAF10
DDB1 and CUL4 associated factor 10
chr17_-_30669133 0.994 NM_022344
C17orf75
chromosome 17 open reading frame 75
chr9_-_127905715 0.988 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr1_-_205782135 0.972 NM_173854
SLC41A1
solute carrier family 41, member 1
chrX_+_119738542 0.967 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr5_+_135468522 0.956 NM_001001419
NM_001001420
NM_005903
SMAD5


SMAD family member 5


chrX_-_40506800 0.953 NM_144970
CXorf38
chromosome X open reading frame 38
chr1_-_53164023 0.944 NM_023077
SELRC1
Sel1 repeat containing 1
chr8_+_110551916 0.937 NM_198120
EBAG9
estrogen receptor binding site associated, antigen, 9
chr1_+_26438267 0.931 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr6_-_8064642 0.923 NM_001199322
NM_001199323
NM_201280
MUTED


muted homolog (mouse)


chrX_-_108976509 0.921 NM_004458
NM_022977
ACSL4

acyl-CoA synthetase long-chain family member 4

chr22_+_39898248 0.911 NM_019008
SMCR7L
Smith-Magenis syndrome chromosome region, candidate 7-like
chr4_-_88141614 0.910 NM_020803
KLHL8
kelch-like 8 (Drosophila)
chr15_-_65425650 0.903 NM_005707
PDCD7
programmed cell death 7
chr7_+_102073953 0.898 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr15_+_59063389 0.889 NM_001040450
NM_001040453
FAM63B

family with sequence similarity 63, member B

chr2_+_120517206 0.887 NM_002830
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr19_-_19843766 0.883 NM_021030
ZNF14
zinc finger protein 14
chr20_+_43514340 0.873 NM_003404
NM_139323
YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

chr7_-_99036317 0.870 NM_015545
PTCD1
pentatricopeptide repeat domain 1
chr8_+_117950437 0.870 NM_001025357
C8orf85
chromosome 8 open reading frame 85
chr5_-_115177261 0.869 NM_004707
ATG12
ATG12 autophagy related 12 homolog (S. cerevisiae)
chr6_+_147525493 0.864 NM_001127715
NM_139244
STXBP5

syntaxin binding protein 5 (tomosyn)

chr17_-_49198084 0.863 NM_001130527
NM_001130528
NM_003971
SPAG9


sperm associated antigen 9


chr1_-_247267625 0.854 NM_001142572
NM_024804
ZNF669

zinc finger protein 669

chrX_-_109561314 0.849 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr9_+_108320382 0.845 NM_001079802
NM_001198963
NM_006731
FKTN


fukutin


chrX_+_154299674 0.844 NM_001018055
NM_001242640
NM_024332
BRCC3


BRCA1/BRCA2-containing complex, subunit 3


chr17_-_47439326 0.843 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr19_+_52800424 0.836 NM_144684
ZNF480
zinc finger protein 480
chr15_-_43662107 0.834 NM_152455
ZSCAN29
zinc finger and SCAN domain containing 29
chrX_+_48432740 0.833 NM_006743
RBM3
RNA binding motif (RNP1, RRM) protein 3
chr8_+_144731829 0.832 NM_014789
ZNF623
zinc finger protein 623
chr3_+_88188261 0.831 NM_018293
ZNF654
zinc finger protein 654
chr12_-_42538432 0.830 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr3_+_101498028 0.823 NM_145037
FAM55C
family with sequence similarity 55, member C
chr13_-_79979913 0.820 NM_022118
RBM26
RNA binding motif protein 26
chr2_+_204103163 0.818 NM_177538
CYP20A1
cytochrome P450, family 20, subfamily A, polypeptide 1
chr6_+_26104103 0.814 NM_003542
HIST2H4B
HIST1H4C
histone cluster 2, H4b
histone cluster 1, H4c
chrX_+_119737743 0.813 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr6_+_136172802 0.806 NM_018945
PDE7B
phosphodiesterase 7B
chr13_-_41706587 0.803 NM_152903
KBTBD6
kelch repeat and BTB (POZ) domain containing 6
chr10_-_14996008 0.798 NM_001033855
NM_001033857
NM_001033858
NM_022487
DCLRE1C



DNA cross-link repair 1C



chr7_-_27224762 0.793 NM_005523
HOXA11
homeobox A11
chr19_+_11485360 0.789 NM_175871
SWSAP1
SWIM-type zinc finger 7 associated protein 1
chr3_+_40566341 0.787 NM_001098414
NM_198484
ZNF621

zinc finger protein 621

chr1_+_100598705 0.785 NM_019083
CCDC76
coiled-coil domain containing 76
chr8_+_110552309 0.784 NM_004215
EBAG9
estrogen receptor binding site associated, antigen, 9
chr3_+_101498285 0.770 NM_001134456
FAM55C
family with sequence similarity 55, member C
chr2_-_152118258 0.763 NM_198557
RBM43
RNA binding motif protein 43
chr5_+_149340287 0.760 NM_000112
SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr1_+_11724148 0.756 NM_018438
FBXO6
F-box protein 6
chr2_+_210636700 0.754 NM_032504
NM_182587
UNC80

unc-80 homolog (C. elegans)

chr19_-_20748540 0.754 NM_001159293
ZNF737
zinc finger protein 737
chr19_+_44556163 0.753 NM_013361
ZNF223
zinc finger protein 223
chr5_-_65017874 0.747 NM_019072
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr17_+_57232859 0.742 NM_018304
PRR11
proline rich 11
chr2_-_95825262 0.742 NM_032788
ZNF514
zinc finger protein 514
chr5_+_130506635 0.741 NM_181705
LYRM7
Lyrm7 homolog (mouse)
chr11_-_62559423 0.737 NM_001080501
TMEM223
transmembrane protein 223
chr1_-_185126153 0.730 NM_001202423
TRMT1L
TRM1 tRNA methyltransferase 1-like
chr19_+_21264952 0.724 NM_182515
ZNF714
zinc finger protein 714
chr11_+_22688156 0.723 NM_001143830
GAS2
growth arrest-specific 2
chr1_-_205180691 0.715 NM_015375
NM_199462
DSTYK

dual serine/threonine and tyrosine protein kinase

chr16_+_21169911 0.714 NM_020422
TMEM159
transmembrane protein 159
chr19_-_4302381 0.709 NM_001169126
NM_144615
TMIGD2

transmembrane and immunoglobulin domain containing 2

chr11_+_22696318 0.707 NM_005256
GAS2
growth arrest-specific 2
chr1_+_204485461 0.706 NM_001204171
NM_001204172
NM_002393
MDM4


Mdm4 p53 binding protein homolog (mouse)


chr16_-_18937722 0.706 NM_015092
SMG1
smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr12_+_4430346 0.696 NM_020375
C12orf5
chromosome 12 open reading frame 5
chr1_-_214724974 0.695 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr7_-_41742666 0.690 NM_002192
INHBA
inhibin, beta A
chr8_+_76452202 0.685 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr6_+_96969669 0.683 NM_015323
UFL1
UFM1-specific ligase 1
chr3_-_156272909 0.682 NM_007107
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr5_+_178450775 0.680 NM_001136116
ZNF879
zinc finger protein 879
chr18_-_61034350 0.679 NM_002035
KDSR
3-ketodihydrosphingosine reductase
chr7_-_108096693 0.678 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr15_+_42840991 0.676 NM_001130447
NM_018097
HAUS2

HAUS augmin-like complex, subunit 2

chr2_-_85839178 0.676 NM_001013649
C2orf68
chromosome 2 open reading frame 68
chr4_-_493441 0.675 NM_133474
ZNF721
zinc finger protein 721
chr19_+_21203425 0.674 NM_001172671
NM_025189
ZNF430

zinc finger protein 430

chr7_+_47694841 0.673 NM_001123065
C7orf65
chromosome 7 open reading frame 65
chr3_-_172428773 0.672 NM_001146276
NM_001146277
NM_001146278
NM_020792
NCEH1



neutral cholesterol ester hydrolase 1



chr3_+_156392204 0.668 NM_015508
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr12_+_123718290 0.668 NM_001143905
C12orf65
chromosome 12 open reading frame 65
chr1_-_185125819 0.667 NM_030934
TRMT1L
TRM1 tRNA methyltransferase 1-like
chr2_-_148779172 0.666 NM_181742
ORC4
origin recognition complex, subunit 4
chr19_-_40023449 0.664 NM_152361
EID2B
EP300 interacting inhibitor of differentiation 2B
chr10_-_70287249 0.663 NM_152707
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr13_+_52598678 0.663 NM_021645
ALG11
UTP14C
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr14_+_75894919 0.662 NM_001135048
NM_130469
JDP2

Jun dimerization protein 2

chr11_+_22689653 0.662 NM_177553
GAS2
growth arrest-specific 2
chr10_-_92681025 0.660 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr2_+_7017795 0.660 NM_080657
RSAD2
radical S-adenosyl methionine domain containing 2
chr9_-_100935173 0.657 NM_003389
CORO2A
coronin, actin binding protein, 2A
chr13_-_108519459 0.657 NM_001080396
FAM155A
family with sequence similarity 155, member A
chr3_-_122746572 0.656 NM_001031702
SEMA5B
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr3_+_156394452 0.655 NM_001184718
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr2_+_67624431 0.653 NM_019002
ETAA1
Ewing tumor-associated antigen 1
chr1_+_26737232 0.653 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr4_-_186125072 0.653 NM_020827
KIAA1430
KIAA1430
chr3_+_156392714 0.653 NM_001184717
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr1_+_53192021 0.651 NM_024646
ZYG11B
zyg-11 homolog B (C. elegans)
chrX_-_77041678 0.651 NM_000489
NM_138270
ATRX

alpha thalassemia/mental retardation syndrome X-linked

chr2_-_216946463 0.647 NM_018441
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr1_+_65730423 0.647 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr7_-_55930444 0.645 NM_207366
SEPT14
septin 14
chr10_+_17794250 0.640 NM_001098844
TMEM236
transmembrane protein 236
chr2_-_74710356 0.633 NM_032779
CCDC142
coiled-coil domain containing 142
chr2_+_99953749 0.632 NM_015904
EIF5B
eukaryotic translation initiation factor 5B
chr14_+_75894508 0.632 NM_001135047
JDP2
Jun dimerization protein 2
chr2_-_172291227 0.632 NM_024770
METTL8
methyltransferase like 8
chr4_-_83931973 0.631 NM_001115008
NM_194282
LIN54

lin-54 homolog (C. elegans)

chr22_+_44319618 0.628 NM_025225
PNPLA3
patatin-like phospholipase domain containing 3
chr10_-_91295310 0.627 NM_213606
SLC16A12
solute carrier family 16, member 12 (monocarboxylic acid transporter 12)
chr3_-_12586962 0.627 NM_001195279
LOC100129480
uncharacterized LOC100129480
chr1_-_205744543 0.616 NM_001135662
NM_001135663
NM_001135664
NM_003929
RAB7L1



RAB7, member RAS oncogene family-like 1



chr5_-_138775213 0.615 NM_152686
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr4_+_164415672 0.615 NM_018352
C4orf43
chromosome 4 open reading frame 43
chr16_+_31724530 0.613 NM_001130913
ZNF720
zinc finger protein 720
chr19_-_14064192 0.612 NM_001146254
NM_001146255
PODNL1

podocan-like 1

chrX_-_19988381 0.611 NM_198279
CXorf23
chromosome X open reading frame 23
chr15_-_40633122 0.608 NM_207380
C15orf52
chromosome 15 open reading frame 52
chr11_+_101785720 0.607 NM_020802
KIAA1377
KIAA1377
chrX_+_109662284 0.607 NM_020769
RGAG1
retrotransposon gag domain containing 1
chr18_-_61089695 0.605 NM_004869
VPS4B
vacuolar protein sorting 4 homolog B (S. cerevisiae)
chr13_+_58205788 0.604 NM_001040429
PCDH17
protocadherin 17
chr10_-_50732142 0.603 NM_170753
PGBD3
piggyBac transposable element derived 3
chr5_+_96211643 0.599 NM_001130140
NM_022350
ERAP2

endoplasmic reticulum aminopeptidase 2

chr10_+_18041217 0.598 NM_001098844
TMEM236
transmembrane protein 236
chr19_+_21688389 0.597 NM_001001415
ZNF429
zinc finger protein 429
chr15_+_79724857 0.595 NM_015206
KIAA1024
KIAA1024
chr4_+_40058507 0.595 NM_018177
N4BP2
NEDD4 binding protein 2
chr2_+_110371887 0.595 NM_023016
ANKRD57
ankyrin repeat domain 57
chr17_+_12569206 0.595 NM_001146312
NM_153604
MYOCD

myocardin

chr6_-_134373618 0.595 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr15_-_49338496 0.594 NM_001193489
NM_014701
SECISBP2L

SECIS binding protein 2-like

chrX_-_50557019 0.590 NM_020717
SHROOM4
shroom family member 4
chr3_+_143692166 0.588 NM_001134470
C3orf58
chromosome 3 open reading frame 58
chr13_-_47470967 0.582 NM_000621
NM_001165947
HTR2A

5-hydroxytryptamine (serotonin) receptor 2A

chr6_+_43543877 0.582 NM_006502
POLH
polymerase (DNA directed), eta
chr3_-_45883562 0.577 NM_020347
LZTFL1
leucine zipper transcription factor-like 1
chr17_-_57970077 0.575 NM_001193609
NM_001193610
NM_001193611
NM_001193612
NM_001193613
NM_016261
TUBD1





tubulin, delta 1





chr6_-_7313352 0.574 NM_003144
SSR1
signal sequence receptor, alpha
chr14_+_75898836 0.574 NM_001135049
JDP2
Jun dimerization protein 2
chr19_+_46001730 0.572 NM_001080401
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr2_+_202122753 0.570 NM_001080125
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr20_+_8112762 0.568 NM_015192
NM_182734
PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

chr9_+_37120468 0.563 NM_032226
ZCCHC7
zinc finger, CCHC domain containing 7
chr19_-_14049167 0.563 NM_024825
PODNL1
podocan-like 1
chr10_-_79789290 0.560 NM_007055
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr7_+_107301079 0.559 NM_000441
SLC26A4
solute carrier family 26, member 4
chr1_+_19578039 0.558 NM_016183
MRTO4
mRNA turnover 4 homolog (S. cerevisiae)
chr1_+_202509241 0.558 NM_001197131
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr3_-_151047309 0.555 NM_176894
P2RY13
purinergic receptor P2Y, G-protein coupled, 13

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.22 3.54e-03 GO:0044260 cellular macromolecule metabolic process
4.20 5.17e-03 GO:0031047 gene silencing by RNA
1.29 1.88e-02 GO:0010468 regulation of gene expression

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 2.19e-04 GO:0043227 membrane-bounded organelle
1.13 2.33e-04 GO:0043231 intracellular membrane-bounded organelle
1.09 4.85e-04 GO:0044424 intracellular part
1.09 8.12e-04 GO:0005622 intracellular
1.11 1.68e-03 GO:0043229 intracellular organelle
1.11 1.84e-03 GO:0043226 organelle
1.16 6.65e-03 GO:0005634 nucleus
3.15 3.54e-02 GO:0035770 RNA granule

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.52 1.22e-09 GO:0008270 zinc ion binding
1.46 1.65e-08 GO:0046914 transition metal ion binding
1.29 1.63e-06 GO:0046872 metal ion binding
1.28 3.07e-06 GO:0043167 ion binding
1.28 3.26e-06 GO:0043169 cation binding
1.26 6.75e-04 GO:0003676 nucleic acid binding