Motif ID: ZFP161.p2

Z-value: 2.393


Transcription factors associated with ZFP161.p2:

Gene SymbolEntrez IDGene Name
ZFP161 7541 zinc finger protein 161 homolog (mouse)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
ZFP161chr18_-_52960130.367.9e-02Click!


Activity profile for motif ZFP161.p2.

activity profile for motif ZFP161.p2


Sorted Z-values histogram for motif ZFP161.p2

Sorted Z-values for motif ZFP161.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZFP161.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_139606916 15.733 NM_152421
FAM69B
family with sequence similarity 69, member B
chr10_-_131762017 12.794 NM_001005463
EBF3
early B-cell factor 3
chr11_-_33890931 12.094 LMO2
LIM domain only 2 (rhombotin-like 1)
chr4_+_41362750 10.531 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr3_+_39851028 10.332 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr13_-_72440143 9.522 DACH1
dachshund homolog 1 (Drosophila)
chr11_-_33891258 9.372 LMO2
LIM domain only 2 (rhombotin-like 1)
chr2_-_28113954 7.079 LOC100302650
uncharacterized LOC100302650
chr3_+_37903643 7.022 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr13_-_77460432 6.932 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr6_+_84743250 6.746 NM_138409
MRAP2
melanocortin 2 receptor accessory protein 2
chr9_+_127020251 6.641 NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr11_-_33891361 6.236 NM_001142316
LMO2
LIM domain only 2 (rhombotin-like 1)
chr18_+_77155943 6.042 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr9_+_127019782 6.031 NM_001166167
NM_001145001
NM_014397
NEK6


NIMA (never in mitosis gene a)-related kinase 6


chr14_-_105635114 6.022 NM_002226
NM_145159
JAG2

jagged 2

chr18_+_77155927 5.825 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr14_-_91526912 5.813 NM_004755
NM_182398
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr9_+_127020462 5.597 NM_001166168
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr9_+_127020242 5.418 NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr18_+_77155966 5.343 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr14_-_105444693 5.282 NM_138420
AHNAK2
AHNAK nucleoprotein 2
chr4_-_102268333 5.216 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr14_-_105634708 5.071 JAG2
jagged 2
chr18_-_22930826 4.978


chr9_-_77703040 4.938 NM_001127603
NM_017881
C9orf95

chromosome 9 open reading frame 95

chr18_+_77155714 4.682 NM_006162
NM_172388
NM_172390
NFATC1


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1


chr12_-_31743822 4.638 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr9_+_139971938 4.490 NM_207309
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr5_-_88179278 4.479 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr8_+_120220554 4.349 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr2_-_74669005 4.199 RTKN
rhotekin
chr6_-_111136330 4.043 CDK19
cyclin-dependent kinase 19
chr9_-_84303595 4.000 NM_005077
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr9_-_140196702 3.958 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr9_+_131314669 3.908 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr1_+_212458867 3.854 NM_006243
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr9_+_127020586 3.747


chr1_+_2160133 3.688 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr13_-_107187312 3.628 NM_004093
EFNB2
ephrin-B2
chr22_-_37915209 3.626 NM_014550
CARD10
caspase recruitment domain family, member 10
chr11_-_33891485 3.619 NM_001142315
LMO2
LIM domain only 2 (rhombotin-like 1)
chr9_+_71320105 3.570 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr2_+_112656200 3.496 MERTK
c-mer proto-oncogene tyrosine kinase
chr9_+_139972195 3.458 UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr2_-_74669026 3.430 RTKN
rhotekin
chr9_-_126030854 3.416 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr9_-_80646150 3.367 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr9_-_126030792 3.349 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr14_+_100438095 3.348 EVL
Enah/Vasp-like
chr2_+_7057471 3.340 NM_014746
RNF144A
ring finger protein 144A
chr9_+_43684800 3.332 NM_001201380
CNTNAP3B
contactin associated protein-like 3B
chr2_+_28616346 3.309 FOSL2
FOS-like antigen 2
chr14_+_61788398 3.307 NM_006255
PRKCH
protein kinase C, eta
chr22_-_29075708 3.305 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr7_+_79764087 3.304 NM_002069
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr5_-_88178964 3.242 MEF2C
myocyte enhancer factor 2C
chr2_+_112656180 3.241 NM_006343
MERTK
c-mer proto-oncogene tyrosine kinase
chr17_-_57184116 3.237 TRIM37
tripartite motif containing 37
chr8_+_37654833 3.218 GPR124
G protein-coupled receptor 124
chr19_+_18530087 3.218 NM_001009998
NM_032627
SSBP4

single stranded DNA binding protein 4

chr19_-_19007395 3.187 CERS1
ceramide synthase 1
chr20_-_62462568 3.080 ZBTB46
zinc finger and BTB domain containing 46
chr6_-_111136407 3.065 NM_015076
CDK19
cyclin-dependent kinase 19
chr2_+_28616360 3.049 FOSL2
FOS-like antigen 2
chr14_+_77228132 3.014 NM_014909
VASH1
vasohibin 1
chr22_+_40441371 3.011 TNRC6B
trinucleotide repeat containing 6B
chr12_-_124018066 2.980 NM_178314
RILPL1
Rab interacting lysosomal protein-like 1
chr4_-_99579540 2.978 NM_005723
TSPAN5
tetraspanin 5
chr1_+_221052735 2.937 NM_021958
HLX
H2.0-like homeobox
chr9_-_134151905 2.893 NM_033387
FAM78A
family with sequence similarity 78, member A
chr2_+_181845368 2.848 UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr2_+_71693817 2.844 NM_001130455
NM_001130982
NM_001130983
NM_001130984
NM_001130985
NM_001130986
NM_001130987
DYSF






dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)






chr1_+_25870143 2.839 LDLRAP1
low density lipoprotein receptor adaptor protein 1
chr5_-_111093251 2.836 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chrX_+_9754465 2.832 NM_001649
SHROOM2
shroom family member 2
chr1_+_61547625 2.830 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr6_-_31865439 2.815 EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr20_+_42543417 2.764 NM_001098797
TOX2
TOX high mobility group box family member 2
chr3_+_32148000 2.740 NM_015141
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr6_-_13486382 2.707 NM_001242628
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr7_-_132261268 2.705 NM_001105543
NM_020911
PLXNA4

plexin A4

chr7_+_12726413 2.698 NM_001037164
NM_212460
ARL4A

ADP-ribosylation factor-like 4A

chr19_+_18530211 2.685 SSBP4
single stranded DNA binding protein 4
chr2_+_12856813 2.639 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr6_-_16761600 2.634 NM_000332
NM_001128164
ATXN1

ataxin 1

chr4_-_102268626 2.619 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr15_-_52587851 2.610 NM_018728
MYO5C
myosin VC
chr14_-_92414004 2.592 NM_006329
FBLN5
fibulin 5
chr2_+_56411123 2.586 NM_001080433
CCDC85A
coiled-coil domain containing 85A
chr17_+_81037504 2.560 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr22_-_31742329 2.559 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr6_-_31865455 2.552 NM_006709
NM_025256
EHMT2

euchromatic histone-lysine N-methyltransferase 2

chr17_+_68165660 2.547 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr12_+_53440809 2.546 NM_198316
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr1_+_65210724 2.541 NM_018211
RAVER2
ribonucleoprotein, PTB-binding 2
chr1_+_212459169 2.532 PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr19_+_18530423 2.487


chr1_-_16162341 2.474 FLJ37453
uncharacterized LOC729614
chr10_-_81205091 2.466 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr2_+_204192915 2.458 NM_005759
ABI2
abl-interactor 2
chr3_+_32148136 2.458 GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr3_-_9595412 2.427 NM_198560
LHFPL4
lipoma HMGIC fusion partner-like 4
chr3_+_8543508 2.418 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr7_-_27183225 2.409 NM_019102
HOXA5
homeobox A5
chr9_-_39288061 2.401 NM_033655
CNTNAP3
contactin associated protein-like 3
chr7_+_12726910 2.389 NM_001195396
NM_005738
ARL4A

ADP-ribosylation factor-like 4A

chr2_-_74669055 2.384 NM_001015055
RTKN
rhotekin
chr9_+_77703412 2.383 OSTF1
osteoclast stimulating factor 1
chr1_+_84543629 2.378 NM_002731
NM_207578
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr8_-_17658385 2.351 NM_001001924
NM_001001925
MTUS1

microtubule associated tumor suppressor 1

chr3_+_110790460 2.332 NM_001243286
NM_015480
PVRL3

poliovirus receptor-related 3

chr1_+_78511588 2.319 NM_017655
GIPC2
GIPC PDZ domain containing family, member 2
chr16_-_88772732 2.308 NM_001171815
RNF166
ring finger protein 166
chr3_+_134514044 2.295 NM_004441
EPHB1
EPH receptor B1
chr4_+_108852671 2.281 NM_183075
CYP2U1
cytochrome P450, family 2, subfamily U, polypeptide 1
chr8_+_37654757 2.273 GPR124
G protein-coupled receptor 124
chr11_+_66624501 2.262 LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr1_+_236305831 2.251 NM_003272
GPR137B
G protein-coupled receptor 137B
chr19_+_32896515 2.227 NM_001172774
DPY19L3
dpy-19-like 3 (C. elegans)
chr18_+_77724575 2.226 NM_001136180
HSBP1L1
heat shock factor binding protein 1-like 1
chr8_-_28243589 2.216 ZNF395
zinc finger protein 395
chr2_+_182756665 2.207 SSFA2
sperm specific antigen 2
chr3_-_194354009 2.202 NM_001011655
NM_001166305
NM_001166306
NM_138399
TMEM44



transmembrane protein 44



chr7_-_35077652 2.187 NM_015283
DPY19L1
dpy-19-like 1 (C. elegans)
chr22_-_39548448 2.176 NM_175709
CBX7
chromobox homolog 7
chr7_-_27213873 2.171 NM_018951
HOXA10
homeobox A10
chr20_+_11871364 2.167 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr17_-_35766762 2.161 NM_198834
NM_198839
ACACA

acetyl-CoA carboxylase alpha

chr9_-_13279562 2.160 MPDZ
multiple PDZ domain protein
chr3_-_47517417 2.153 NM_012235
SCAP
SREBF chaperone
chr8_-_4852262 2.133 NM_033225
CSMD1
CUB and Sushi multiple domains 1
chr5_+_139028025 2.116 NM_016463
CXXC5
CXXC finger protein 5
chr22_-_31742217 2.085 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr12_+_13197284 2.082 NM_020853
KIAA1467
KIAA1467
chr9_-_72287097 2.076 NM_001163
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr1_+_153651050 2.071 NM_000906
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr9_+_128509616 2.065 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr14_+_38678280 2.047 SSTR1
somatostatin receptor 1
chr22_-_50699938 2.013 NM_002969
MAPK12
mitogen-activated protein kinase 12
chr1_+_210502188 2.004 NM_001170587
NM_001170588
NM_018194
HHAT


hedgehog acyltransferase


chr3_-_194353908 1.975 TMEM44
transmembrane protein 44
chr2_+_220094478 1.969 NM_018089
NM_001042410
ANKZF1

ankyrin repeat and zinc finger domain containing 1

chr12_+_8850479 1.964 NM_020734
RIMKLB
ribosomal modification protein rimK-like family member B
chr4_+_123747815 1.963 NM_002006
FGF2
fibroblast growth factor 2 (basic)
chr10_+_94608224 1.951 NM_019053
EXOC6
exocyst complex component 6
chr2_+_11052062 1.948 NM_002236
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr8_-_74659082 1.948 NM_001164380
NM_001164381
NM_001164382
NM_001164383
NM_001164385
NM_014393
STAU2





staufen, RNA binding protein, homolog 2 (Drosophila)





chr13_+_114238978 1.931 TFDP1
transcription factor Dp-1
chr19_-_19006868 1.925 NM_021267
NM_198207
NM_001492
CERS1

GDF1
ceramide synthase 1

growth differentiation factor 1
chr12_-_57824787 1.924 R3HDM2
R3H domain containing 2
chr9_-_100459623 1.922 NM_000380
XPA
xeroderma pigmentosum, complementation group A
chr11_+_86748870 1.916 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr1_+_92495484 1.914 NM_173567
EPHX4
epoxide hydrolase 4
chr9_-_100459556 1.907 XPA
xeroderma pigmentosum, complementation group A
chr1_+_178694273 1.906 NM_152663
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr9_-_124990706 1.875 NM_001242333
LHX6
LIM homeobox 6
chr20_-_23030141 1.868 NM_000361
THBD
thrombomodulin
chr20_+_306205 1.861 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr3_+_8543539 1.858 LMCD1
LIM and cysteine-rich domains 1
chr1_+_87380437 1.855 HS2ST1
heparan sulfate 2-O-sulfotransferase 1
chr6_-_32163890 1.854 NOTCH4
notch 4
chr16_-_4166185 1.828 NM_001116
ADCY9
adenylate cyclase 9
chr15_+_96873845 1.826 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr11_+_43963809 1.819 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr8_-_9009050 1.791 NM_001201329
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr14_-_92413738 1.790 FBLN5
fibulin 5
chr14_+_65879694 1.784 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr5_+_139027907 1.783 CXXC5
CXXC finger protein 5
chr17_+_2240795 1.777 NM_014853
NM_001098509
SGSM2

small G protein signaling modulator 2

chr4_+_123747939 1.774 FGF2
fibroblast growth factor 2 (basic)
chr4_-_102267952 1.773 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr21_+_46293925 1.768


chrX_-_34675366 1.767 NM_031442
TMEM47
transmembrane protein 47
chr11_+_925795 1.763 NM_001242837
NM_012305
AP2A2

adaptor-related protein complex 2, alpha 2 subunit

chr6_-_52441714 1.759 TRAM2
translocation associated membrane protein 2
chr6_+_24495166 1.752 NM_001080
NM_170740
ALDH5A1

aldehyde dehydrogenase 5 family, member A1

chr17_-_19770988 1.750 NM_001142610
NM_014683
ULK2

unc-51-like kinase 2 (C. elegans)

chr17_+_5973640 1.747 NM_015253
WSCD1
WSC domain containing 1
chr11_+_74459900 1.743 NM_001098638
RNF169
ring finger protein 169
chr12_-_29936685 1.742 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr11_+_925899 1.734 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr12_-_42983412 1.734 NM_153026
PRICKLE1
prickle homolog 1 (Drosophila)
chr9_+_102584136 1.734 NM_006981
NM_173199
NM_173200
NR4A3


nuclear receptor subfamily 4, group A, member 3


chr9_+_82187469 1.721 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr3_+_170075449 1.718 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr6_+_96025343 1.700 NM_024641
MANEA
mannosidase, endo-alpha
chr17_-_65989583 1.698 NM_181655
NM_181656
C17orf58

chromosome 17 open reading frame 58

chr11_+_925874 1.694 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr14_+_105780903 1.694 PACS2
phosphofurin acidic cluster sorting protein 2
chr6_-_13487772 1.680 NM_001242629
NM_018988
GFOD1

glucose-fructose oxidoreductase domain containing 1

chr1_+_25870043 1.677 NM_015627
LDLRAP1
low density lipoprotein receptor adaptor protein 1
chr2_-_220094354 1.676 NM_001077198
NM_024085
ATG9A

ATG9 autophagy related 9 homolog A (S. cerevisiae)

chr13_-_110438896 1.674 NM_003749
IRS2
insulin receptor substrate 2
chr1_-_59248287 1.674 JUN
jun proto-oncogene
chr6_-_146285225 1.674 NM_001042683
NM_173082
SHPRH

SNF2 histone linker PHD RING helicase

chr5_-_111093792 1.672 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr12_-_59314069 1.663 NM_153377
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr1_-_214724844 1.662 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr20_-_46414636 1.661 NM_018837
SULF2
sulfatase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.19 1.02e-11 GO:0044237 cellular metabolic process
1.16 1.29e-09 GO:0008152 metabolic process
1.22 2.19e-09 GO:0044260 cellular macromolecule metabolic process
1.16 5.18e-08 GO:0044238 primary metabolic process
1.55 8.54e-08 GO:0051128 regulation of cellular component organization
1.49 1.22e-07 GO:0006793 phosphorus metabolic process
1.49 1.22e-07 GO:0006796 phosphate metabolic process
1.34 2.90e-07 GO:0006464 protein modification process
1.09 5.78e-07 GO:0009987 cellular process
1.33 6.29e-07 GO:0043412 macromolecule modification
1.18 1.26e-06 GO:0043170 macromolecule metabolic process
1.14 2.91e-06 GO:0050794 regulation of cellular process
1.29 1.03e-05 GO:0048523 negative regulation of cellular process
1.13 1.11e-05 GO:0050789 regulation of biological process
1.24 1.93e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.44 2.00e-04 GO:0016310 phosphorylation
1.25 2.43e-04 GO:0048519 negative regulation of biological process
1.23 4.45e-04 GO:0044267 cellular protein metabolic process
1.48 5.72e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.46 8.51e-04 GO:0009890 negative regulation of biosynthetic process
1.23 9.53e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.48 1.01e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.38 1.17e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.10 1.26e-03 GO:0065007 biological regulation
1.47 1.35e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.45 1.59e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.61 3.22e-03 GO:0016568 chromatin modification
1.18 3.29e-03 GO:0080090 regulation of primary metabolic process
1.18 3.35e-03 GO:0016043 cellular component organization
1.21 3.35e-03 GO:0031326 regulation of cellular biosynthetic process
1.29 3.49e-03 GO:0007399 nervous system development
1.21 3.49e-03 GO:0009889 regulation of biosynthetic process
1.17 3.50e-03 GO:0031323 regulation of cellular metabolic process
1.46 4.13e-03 GO:0051276 chromosome organization
1.18 4.88e-03 GO:0060255 regulation of macromolecule metabolic process
1.49 5.01e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.35 5.04e-03 GO:0009892 negative regulation of metabolic process
1.47 9.19e-03 GO:0051253 negative regulation of RNA metabolic process
1.36 1.01e-02 GO:0031324 negative regulation of cellular metabolic process
1.16 1.05e-02 GO:0032502 developmental process
1.44 1.09e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44 1.27e-02 GO:0010629 negative regulation of gene expression
1.39 1.64e-02 GO:0006468 protein phosphorylation
1.49 1.78e-02 GO:0072358 cardiovascular system development
1.49 1.78e-02 GO:0072359 circulatory system development
1.40 1.85e-02 GO:0009790 embryo development
1.20 1.97e-02 GO:0010468 regulation of gene expression
1.71 2.18e-02 GO:0051129 negative regulation of cellular component organization
1.42 2.23e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.21 2.45e-02 GO:0051252 regulation of RNA metabolic process
1.17 2.54e-02 GO:0048856 anatomical structure development
1.19 2.80e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15 2.95e-02 GO:0019222 regulation of metabolic process
1.34 3.18e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.16 3.34e-02 GO:0071840 cellular component organization or biogenesis
1.47 4.09e-02 GO:0006325 chromatin organization
1.45 4.32e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.24 4.72e-02 GO:0006996 organelle organization
1.19 4.74e-02 GO:0071842 cellular component organization at cellular level
1.21 4.77e-02 GO:0006355 regulation of transcription, DNA-dependent

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 6.20e-21 GO:0005622 intracellular
1.13 1.54e-20 GO:0044424 intracellular part
1.16 1.30e-17 GO:0043227 membrane-bounded organelle
1.16 1.53e-17 GO:0043231 intracellular membrane-bounded organelle
1.14 2.77e-17 GO:0043229 intracellular organelle
1.14 3.71e-17 GO:0043226 organelle
1.14 9.90e-12 GO:0005737 cytoplasm
1.18 9.23e-10 GO:0005634 nucleus
1.15 6.17e-07 GO:0044444 cytoplasmic part
1.04 1.81e-06 GO:0044464 cell part
1.04 1.92e-06 GO:0005623 cell
2.06 2.59e-05 GO:0005912 adherens junction
1.14 1.08e-04 GO:0044446 intracellular organelle part
1.93 1.89e-04 GO:0070161 anchoring junction
1.13 3.06e-04 GO:0044422 organelle part
1.22 1.63e-03 GO:0044428 nuclear part
2.01 1.07e-02 GO:0005925 focal adhesion
1.19 1.84e-02 GO:0070013 intracellular organelle lumen
1.21 2.32e-02 GO:0031981 nuclear lumen
1.25 2.63e-02 GO:0005654 nucleoplasm
1.18 2.98e-02 GO:0043233 organelle lumen
1.18 3.46e-02 GO:0031974 membrane-enclosed lumen
1.92 3.49e-02 GO:0005924 cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 7.17e-10 GO:0005515 protein binding
1.08 2.89e-09 GO:0005488 binding
1.15 9.66e-06 GO:0003824 catalytic activity
1.45 1.01e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.43 1.47e-04 GO:0016301 kinase activity
1.17 2.92e-04 GO:0046872 metal ion binding
1.47 3.82e-04 GO:0004672 protein kinase activity
1.16 4.02e-04 GO:0043167 ion binding
1.16 4.35e-04 GO:0043169 cation binding
1.28 5.29e-04 GO:0030554 adenyl nucleotide binding
1.37 1.01e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.27 1.21e-03 GO:0032559 adenyl ribonucleotide binding
1.52 1.99e-03 GO:0004674 protein serine/threonine kinase activity
1.21 2.68e-03 GO:0000166 nucleotide binding
1.26 2.92e-03 GO:0005524 ATP binding
1.24 5.05e-03 GO:0016740 transferase activity
1.20 6.80e-03 GO:0003677 DNA binding
1.76 2.26e-02 GO:0000287 magnesium ion binding
1.52 2.67e-02 GO:0042578 phosphoric ester hydrolase activity
1.21 3.06e-02 GO:0017076 purine nucleotide binding
1.29 3.46e-02 GO:0001071 nucleic acid binding transcription factor activity
1.29 3.46e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.35 3.72e-02 GO:0016788 hydrolase activity, acting on ester bonds