Motif ID: ZNF423.p2

Z-value: 1.639


Transcription factors associated with ZNF423.p2:

Gene SymbolEntrez IDGene Name
ZNF423 23090 zinc finger protein 423

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
ZNF423chr16_-_49860917-0.792.2e-06Click!


Activity profile for motif ZNF423.p2.

activity profile for motif ZNF423.p2


Sorted Z-values histogram for motif ZNF423.p2

Sorted Z-values for motif ZNF423.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF423.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_184943532 10.242 FAM129A
family with sequence similarity 129, member A
chr17_+_77020278 7.364 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr3_-_127541975 5.892 NM_001003794
MGLL
monoglyceride lipase
chr4_-_120549115 5.880 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr12_+_113344738 5.846 NM_001032409
NM_002534
NM_016816
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr4_+_74735107 5.797 NM_001511
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr21_+_27012067 5.358 JAM2
junctional adhesion molecule 2
chr11_+_69455978 5.204 CCND1
cyclin D1
chr21_+_27011766 5.118 JAM2
junctional adhesion molecule 2
chr17_+_77020229 4.874 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr12_+_113344811 4.869 OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr11_-_441995 4.684 NM_001012302
ANO9
anoctamin 9
chr21_+_26934440 4.309 MIR155HG
MIR155 host gene (non-protein coding)
chr11_-_441956 4.232 ANO9
anoctamin 9
chrX_+_30265270 3.886 NM_177404
MAGEB1
melanoma antigen family B, 1
chr2_-_224903933 3.618 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr3_-_127541160 3.607 NM_007283
MGLL
monoglyceride lipase
chr8_+_145065366 3.481 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr9_-_100881462 3.341 NM_014788
NM_033219
NM_033220
TRIM14


tripartite motif containing 14


chr21_+_27012045 3.203 JAM2
junctional adhesion molecule 2
chr1_+_205198058 3.078 NM_001242925
TMCC2
transmembrane and coiled-coil domain family 2
chr14_+_96671015 3.018 NM_000623
BDKRB2
bradykinin receptor B2
chr6_+_109761887 2.960 NM_003080
SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr19_-_47734215 2.913 NM_014417
BBC3
BCL2 binding component 3
chr7_-_97601654 2.879


chr6_-_3227776 2.690 NM_178012
TUBB2B
tubulin, beta 2B class IIb
chr12_-_50101192 2.688 NM_175736
NM_198900
FMNL3

formin-like 3

chr9_+_116918230 2.590 NM_032888
COL27A1
collagen, type XXVII, alpha 1
chr12_-_50101127 2.494 FMNL3
formin-like 3
chr1_-_156721501 2.363 NM_004494
HDGF
hepatoma-derived growth factor
chr1_-_212873306 2.325 NM_018664
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr1_-_212873197 2.316 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr3_-_158450205 2.260 RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr3_-_158450271 2.205 NM_002888
NM_206963
RARRES1

retinoic acid receptor responder (tazarotene induced) 1

chr6_+_11094265 2.200 NM_001135575
C6orf228
chromosome 6 open reading frame 228
chr19_+_14544100 2.177 NM_002741
PKN1
protein kinase N1
chr4_+_20255234 2.158 NM_004787
SLIT2
slit homolog 2 (Drosophila)
chr3_+_72937168 2.110 NM_001080393
GXYLT2
glucoside xylosyltransferase 2
chr3_-_122283423 2.075 NM_001146103
NM_031458
PARP9

poly (ADP-ribose) polymerase family, member 9

chr19_+_45147207 2.044 PVR
poliovirus receptor
chr6_-_143266283 1.992 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr7_-_19184984 1.976 NM_152898
FERD3L
Fer3-like (Drosophila)
chr4_-_169401603 1.973 NM_001012967
DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr19_+_20959109 1.964


chr6_+_109762204 1.960 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr7_+_26191732 1.958 NM_004289
NFE2L3
nuclear factor (erythroid-derived 2)-like 3
chr9_+_109625347 1.944 NM_021224
ZNF462
zinc finger protein 462
chr8_-_80679897 1.878 NM_001040708
NM_012258
HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr17_-_37764165 1.851 NM_006160
NEUROD2
neurogenic differentiation 2
chr3_-_16555128 1.822 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr1_-_184943673 1.798 NM_052966
FAM129A
family with sequence similarity 129, member A
chr10_-_100027943 1.768 NM_032211
LOXL4
lysyl oxidase-like 4
chr4_+_8582216 1.768 NM_080819
GPR78
G protein-coupled receptor 78
chr10_-_121296044 1.753 NM_002925
RGS10
regulator of G-protein signaling 10
chr3_-_158450230 1.699 RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr6_+_109762043 1.694 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr7_-_23053732 1.693 NM_032581
FAM126A
family with sequence similarity 126, member A
chr3_-_58563070 1.681 FAM107A
family with sequence similarity 107, member A
chr5_+_131746579 1.675 C5orf56
chromosome 5 open reading frame 56
chr3_+_6902797 1.667 NM_000844
NM_181874
GRM7

glutamate receptor, metabotropic 7

chr1_+_955468 1.651 NM_198576
AGRN
agrin
chr22_-_37823503 1.598 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr17_+_74380676 1.597 NM_001142601
NM_021972
NM_182965
SPHK1


sphingosine kinase 1


chr19_+_45147090 1.595 NM_001135768
NM_001135769
NM_001135770
NM_006505
PVR



poliovirus receptor



chr7_-_23053674 1.552 FAM126A
family with sequence similarity 126, member A
chr6_-_30654978 1.539 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr16_-_65155984 1.537 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr3_-_16554992 1.535 RFTN1
raftlin, lipid raft linker 1
chr8_-_119964059 1.529 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chrX_+_136648313 1.487 NM_003413
ZIC3
Zic family member 3
chr19_+_14544216 1.467 PKN1
protein kinase N1
chr20_+_30865435 1.444 NM_004798
KIF3B
kinesin family member 3B
chr10_+_104154228 1.439 NM_001077493
NM_001077494
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr22_+_37309618 1.427 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr2_+_65215577 1.421 NM_001193493
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr4_-_74904329 1.414 NM_002090
CXCL3
chemokine (C-X-C motif) ligand 3
chr10_-_60027630 1.387 NM_152230
IPMK
inositol polyphosphate multikinase
chr10_+_82213892 1.385 NM_001128309
NM_030927
TSPAN14

tetraspanin 14

chr19_+_45582469 1.383 NM_001007270
NM_001007269
NM_024707
GEMIN7


gem (nuclear organelle) associated protein 7


chr5_+_170736287 1.382 NM_021025
TLX3
T-cell leukemia homeobox 3
chr6_+_11093991 1.375 C6orf228
chromosome 6 open reading frame 228
chr19_+_45147180 1.369 PVR
poliovirus receptor
chr1_+_27320132 1.368 NM_001013642
TRNP1
TMF1-regulated nuclear protein 1
chr11_-_61658853 1.367 NM_021727
FADS3
fatty acid desaturase 3
chr3_-_50374749 1.359 RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr6_-_31239489 1.356 HLA-B
HLA-C
major histocompatibility complex, class I, B
major histocompatibility complex, class I, C
chr19_-_1863546 1.338 NM_031918
KLF16
Kruppel-like factor 16
chr21_-_18985224 1.336 NM_001130914
NM_006806
BTG3

BTG family, member 3

chr2_-_175869910 1.335 NM_001822
NM_001025201
CHN1

chimerin (chimaerin) 1

chr10_+_82214074 1.332 TSPAN14
tetraspanin 14
chr1_+_10459084 1.324 NM_002631
PGD
phosphogluconate dehydrogenase
chr2_-_204399906 1.316 NM_203365
NM_213589
RAPH1

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

chr3_-_50374795 1.304 RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr10_+_70715883 1.299 NM_004728
DDX21
DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
chr6_-_43596764 1.273 GTPBP2
GTP binding protein 2
chr16_+_57392694 1.272 NM_002990
CCL22
chemokine (C-C motif) ligand 22
chr14_-_53258329 1.271 NM_198066
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr1_+_19578039 1.258 NM_016183
MRTO4
mRNA turnover 4 homolog (S. cerevisiae)
chr3_-_50374875 1.252 NM_170713
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr9_+_112542496 1.249 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr13_-_43566301 1.242 NM_001002264
NM_033255
EPSTI1

epithelial stromal interaction 1 (breast)

chr6_+_31543340 1.225 NM_000594
TNF
tumor necrosis factor
chr9_+_72658735 1.212 MAMDC2
MAM domain containing 2
chr11_-_61062697 1.211 NM_152718
VWCE
von Willebrand factor C and EGF domains
chr14_-_77279179 1.192 ANGEL1
angel homolog 1 (Drosophila)
chr12_+_111471827 1.191 NM_015267
CUX2
cut-like homeobox 2
chr6_+_43603554 1.188 NM_014628
MAD2L1BP
MAD2L1 binding protein
chr16_-_65155965 1.186 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr17_+_74381419 1.184 SPHK1
sphingosine kinase 1
chr19_+_38810751 1.162 KCNK6
potassium channel, subfamily K, member 6
chr20_-_44539542 1.151 PLTP
phospholipid transfer protein
chr1_+_1447495 1.146 NM_001170535
NM_018188
ATAD3A

ATPase family, AAA domain containing 3A

chr19_-_10420220 1.110 NM_001103167
ZGLP1
zinc finger, GATA-like protein 1
chr7_-_152373163 1.110 NM_005431
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr1_+_1407112 1.103 ATAD3B
ATPase family, AAA domain containing 3B
chr3_-_45838112 1.095 SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr1_+_9711781 1.092 NM_005026
PIK3CD
phosphoinositide-3-kinase, catalytic, delta polypeptide
chrX_-_19140581 1.087 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr21_+_45161343 1.085 PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr1_-_26644755 1.079 NM_145345
UBXN11
UBX domain protein 11
chr7_+_103969103 1.074 NM_199000
LHFPL3
lipoma HMGIC fusion partner-like 3
chr6_-_90062610 1.067 NM_016021
UBE2J1
ubiquitin-conjugating enzyme E2, J1, U
chr3_-_98620452 1.065 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chrX_-_136113832 1.058 NM_054021
GPR101
G protein-coupled receptor 101
chr14_-_69259654 1.056 ZFP36L1
zinc finger protein 36, C3H type-like 1
chr19_-_1863425 1.053 KLF16
Kruppel-like factor 16
chr21_+_45719921 1.049 NM_002626
PFKL
phosphofructokinase, liver
chr4_-_74964836 1.044 CXCL2
chemokine (C-X-C motif) ligand 2
chr14_-_65438794 1.042 NM_198686
RAB15
RAB15, member RAS onocogene family
chr11_+_118307072 1.042 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr2_+_171785624 1.041 GORASP2
golgi reassembly stacking protein 2, 55kDa
chr13_-_110959441 1.031 NM_001845
COL4A1
collagen, type IV, alpha 1
chr3_-_122283077 1.027 NM_001146102
NM_001146105
NM_001146104
NM_001146106
PARP9



poly (ADP-ribose) polymerase family, member 9



chr20_-_44539597 1.026 NM_001242921
PLTP
phospholipid transfer protein
chr10_+_115438934 1.021 NM_033340
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr16_-_65155881 1.020 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr16_+_30675777 1.019 NM_001105079
FBRS
fibrosin
chr1_+_1447537 1.017 ATAD3A
ATAD3B
ATPase family, AAA domain containing 3A
ATPase family, AAA domain containing 3B
chr1_+_1407158 0.998 NM_031921
ATAD3B
ATPase family, AAA domain containing 3B
chr19_+_38810461 0.984 NM_004823
KCNK6
potassium channel, subfamily K, member 6
chr5_-_150460599 0.977 NM_001252385
NM_001252386
NM_001252393
NM_006058
TNIP1



TNFAIP3 interacting protein 1



chr5_-_176057324 0.976 NM_001001502
NM_003085
SNCB

synuclein, beta

chr2_+_171785780 0.976 GORASP2
golgi reassembly stacking protein 2, 55kDa
chr17_+_72733350 0.974 NM_001006638
NM_001163990
RAB37

RAB37, member RAS oncogene family

chr14_-_77279242 0.973 NM_015305
ANGEL1
angel homolog 1 (Drosophila)
chr22_-_31503484 0.967 NM_080430
SELM
selenoprotein M
chr1_-_156023488 0.952 NM_020131
UBQLN4
ubiquilin 4
chr19_+_3224734 0.947 CELF5
CUGBP, Elav-like family member 5
chr17_-_31203889 0.945 NM_015194
MYO1D
myosin ID
chr8_-_121823696 0.939 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr12_-_120554612 0.936 NM_001167606
NM_006861
RAB35

RAB35, member RAS oncogene family

chr19_+_42817434 0.936 NM_173633
TMEM145
transmembrane protein 145
chr9_-_133814422 0.933 NM_001145106
FIBCD1
fibrinogen C domain containing 1
chr1_+_955536 0.930


chr4_+_57371374 0.920 NM_206919
ARL9
ADP-ribosylation factor-like 9
chr19_-_11545900 0.909 NM_145045
CCDC151
coiled-coil domain containing 151
chr1_-_151299822 0.907 PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr3_+_122283139 0.907 NM_138287
DTX3L
deltex 3-like (Drosophila)
chr7_-_107880492 0.905 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr4_-_169401571 0.903 DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr11_-_117698727 0.901 NM_021603
FXYD2
FXYD domain containing ion transport regulator 2
chr21_+_45719964 0.901 PFKL
phosphofructokinase, liver
chr19_+_19649056 0.896 NM_153221
CILP2
cartilage intermediate layer protein 2
chr2_+_46769821 0.884 NM_012249
RHOQ
ras homolog gene family, member Q
chr18_-_71959109 0.881 NM_001190807
NM_001914
NM_148923
CYB5A


cytochrome b5 type A (microsomal)


chr9_+_93564063 0.879 SYK
spleen tyrosine kinase
chr17_+_72732958 0.879 NM_001163989
RAB37
RAB37, member RAS oncogene family
chr5_+_129240453 0.874 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr13_+_110959592 0.874 NM_001846
COL4A2
collagen, type IV, alpha 2
chr6_-_134639195 0.871 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr2_-_39348127 0.870 SOS1
son of sevenless homolog 1 (Drosophila)
chr16_+_27325244 0.865 NM_000418
NM_001008699
IL4R

interleukin 4 receptor

chr17_+_1619816 0.859 NM_001163673
NM_152348
WDR81

WD repeat domain 81

chr12_-_77459198 0.857 NM_203394
E2F7
E2F transcription factor 7
chr19_+_38810540 0.852 KCNK6
potassium channel, subfamily K, member 6
chr9_+_93564073 0.847 SYK
spleen tyrosine kinase
chr9_+_131549509 0.845 NM_018201
TBC1D13
TBC1 domain family, member 13
chr19_+_8117645 0.841 NM_001201359
NM_005624
CCL25

chemokine (C-C motif) ligand 25

chr16_+_31044881 0.837 NM_004604
STX4
syntaxin 4
chr6_+_151186884 0.833 MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr19_-_8408120 0.833 NM_198471
KANK3
KN motif and ankyrin repeat domains 3
chr12_-_120554558 0.831 RAB35
RAB35, member RAS oncogene family
chr18_-_5543967 0.830 NM_012307
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr6_+_43603588 0.825 MAD2L1BP
MAD2L1 binding protein
chr11_-_105892908 0.823 NM_032424
KIAA1826
KIAA1826
chr5_+_169010637 0.820 NM_017785
CCDC99
coiled-coil domain containing 99
chr6_-_90062289 0.816 UBE2J1
ubiquitin-conjugating enzyme E2, J1, U
chr9_+_131549561 0.813 TBC1D13
TBC1 domain family, member 13
chr2_-_233352530 0.809 NM_004826
ECEL1
endothelin converting enzyme-like 1
chr11_+_66024746 0.808 NM_001134775
KLC2
kinesin light chain 2
chr9_+_103189494 0.807 NM_001198807
NM_080655
NM_001198805
C9orf30


chromosome 9 open reading frame 30


chr15_-_75660905 0.801 NM_006715
MAN2C1
mannosidase, alpha, class 2C, member 1
chr16_+_31044849 0.799 STX4
syntaxin 4
chr12_-_120554557 0.797 RAB35
RAB35, member RAS oncogene family
chr17_+_79633724 0.794 NM_199287
CCDC137
coiled-coil domain containing 137
chr4_-_20985547 0.792 KCNIP4
Kv channel interacting protein 4
chr22_-_50946020 0.786 LMF2
lipase maturation factor 2
chr17_+_8924822 0.784 NM_004822
NTN1
netrin 1
chr17_-_7518124 0.782 NM_004860
FXR2
fragile X mental retardation, autosomal homolog 2
chr18_+_33877630 0.780 NM_025135
FHOD3
formin homology 2 domain containing 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.18 1.89e-05 GO:0065007 biological regulation
1.31 5.24e-05 GO:0023052 signaling
1.18 6.06e-05 GO:0050789 regulation of biological process
1.19 8.75e-05 GO:0050794 regulation of cellular process
1.31 1.96e-04 GO:0007165 signal transduction
1.27 2.10e-04 GO:0051716 cellular response to stimulus
1.49 5.86e-04 GO:0007399 nervous system development
1.32 1.62e-02 GO:0048519 negative regulation of biological process
3.08 2.13e-02 GO:0008629 induction of apoptosis by intracellular signals
1.37 2.35e-02 GO:0007166 cell surface receptor linked signaling pathway
1.09 3.62e-02 GO:0009987 cellular process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.31 7.70e-03 GO:0044459 plasma membrane part
2.97 4.64e-02 GO:0031256 leading edge membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 1.97e-05 GO:0005515 protein binding
1.54 2.79e-02 GO:0019899 enzyme binding