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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ARNT

Z-value: 1.12

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Transcription factors associated with ARNT

Gene Symbol Gene ID Gene Info
ENSG00000143437.16 aryl hydrocarbon receptor nuclear translocator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARNThg19_v2_chr1_-_150849174_150849200,
hg19_v2_chr1_-_150849047_150849085
0.423.8e-02Click!

Activity profile of ARNT motif

Sorted Z-values of ARNT motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_26934165 5.49 ENST00000456917.1
MIR155 host gene (non-protein coding)
chr8_+_17354617 4.59 ENST00000470360.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr1_+_65613852 4.44 ENST00000327299.7
adenylate kinase 4
chr8_+_17354587 4.42 ENST00000494857.1
ENST00000522656.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr15_+_89182156 3.78 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr15_+_89182178 3.73 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr5_-_131826457 3.38 ENST00000437654.1
ENST00000245414.4
interferon regulatory factor 1
chr15_+_89181974 3.24 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr3_+_5020801 3.14 ENST00000256495.3
basic helix-loop-helix family, member e40
chr2_-_10587897 2.73 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chr10_-_49732281 2.06 ENST00000374170.1
Rho GTPase activating protein 22
chr3_+_133292574 2.05 ENST00000264993.3
CDV3 homolog (mouse)
chr8_+_104383728 1.92 ENST00000330295.5
collagen triple helix repeat containing 1
chr5_-_131563501 1.85 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
prolyl 4-hydroxylase, alpha polypeptide II
chr11_+_69455855 1.82 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr2_-_11810284 1.80 ENST00000306928.5
neurotensin receptor 2
chr9_+_35732312 1.78 ENST00000353704.2
cAMP responsive element binding protein 3
chr1_+_209848749 1.75 ENST00000367029.4
G0/G1switch 2
chr10_+_101419187 1.74 ENST00000370489.4
ectonucleoside triphosphate diphosphohydrolase 7
chr5_-_121413974 1.72 ENST00000231004.4
lysyl oxidase
chr2_+_75061108 1.69 ENST00000290573.2
hexokinase 2
chr6_+_43739697 1.66 ENST00000230480.6
vascular endothelial growth factor A
chr15_+_52311398 1.64 ENST00000261845.5
mitogen-activated protein kinase 6
chr3_+_133292759 1.64 ENST00000431519.2
CDV3 homolog (mouse)
chr17_-_41623716 1.62 ENST00000319349.5
ets variant 4
chr17_+_40440481 1.61 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
signal transducer and activator of transcription 5A
chr6_-_154831779 1.53 ENST00000607772.1
CNKSR family member 3
chr3_+_133292851 1.53 ENST00000503932.1
CDV3 homolog (mouse)
chr11_-_59436453 1.52 ENST00000300146.9
protein associated with topoisomerase II homolog 1 (yeast)
chr22_-_42017021 1.45 ENST00000263256.6
desumoylating isopeptidase 1
chr5_+_110427983 1.45 ENST00000513710.2
ENST00000505303.1
WD repeat domain 36
chr19_+_10765699 1.44 ENST00000590009.1
interleukin enhancer binding factor 3, 90kDa
chr3_-_156272924 1.42 ENST00000467789.1
ENST00000265044.2
signal sequence receptor, gamma (translocon-associated protein gamma)
chr8_+_126442563 1.41 ENST00000311922.3
tribbles pseudokinase 1
chr13_-_44361025 1.41 ENST00000261488.6
ecto-NOX disulfide-thiol exchanger 1
chr20_-_10654639 1.41 ENST00000254958.5
jagged 1
chr11_-_64646086 1.39 ENST00000320631.3
EH-domain containing 1
chr3_-_145878954 1.38 ENST00000282903.5
ENST00000360060.3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr11_+_18416103 1.35 ENST00000543445.1
ENST00000430553.2
ENST00000396222.2
ENST00000535451.1
lactate dehydrogenase A
chr8_-_37756972 1.31 ENST00000330843.4
ENST00000522727.1
ENST00000287263.4
RAB11 family interacting protein 1 (class I)
chr11_+_18416133 1.31 ENST00000227157.4
ENST00000478970.2
ENST00000495052.1
lactate dehydrogenase A
chr12_-_51422017 1.30 ENST00000394904.3
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr15_+_98503922 1.27 ENST00000268042.6
arrestin domain containing 4
chr9_-_138591341 1.26 ENST00000298466.5
ENST00000425225.1
spermatogenesis and oogenesis specific basic helix-loop-helix 1
chr2_+_219433588 1.22 ENST00000295701.5
RCD1 required for cell differentiation1 homolog (S. pombe)
chr10_-_133795416 1.18 ENST00000540159.1
ENST00000368636.4
BCL2/adenovirus E1B 19kDa interacting protein 3
chr7_-_139876812 1.16 ENST00000397560.2
lysine (K)-specific demethylase 7A
chr2_+_173420697 1.15 ENST00000282077.3
ENST00000392571.2
ENST00000410055.1
pyruvate dehydrogenase kinase, isozyme 1
chr1_-_8939265 1.15 ENST00000489867.1
enolase 1, (alpha)
chr12_-_121734489 1.13 ENST00000412367.2
ENST00000402834.4
ENST00000404169.3
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr3_+_32859510 1.13 ENST00000383763.5
tripartite motif containing 71, E3 ubiquitin protein ligase
chr21_+_45719921 1.09 ENST00000349048.4
phosphofructokinase, liver
chr1_+_227058264 1.09 ENST00000366783.3
ENST00000340188.4
ENST00000495488.1
ENST00000422240.2
presenilin 2 (Alzheimer disease 4)
chr11_+_57435219 1.08 ENST00000527985.1
ENST00000287169.3
zinc finger, DHHC-type containing 5
chr5_+_67584174 1.08 ENST00000320694.8
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr2_+_219433281 1.08 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr18_+_23806437 1.07 ENST00000578121.1
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr8_-_90996459 1.07 ENST00000517337.1
ENST00000409330.1
nibrin
chr1_-_31712401 1.06 ENST00000373736.2
Na+/K+ transporting ATPase interacting 1
chr2_+_192543153 1.06 ENST00000425611.2
nucleic acid binding protein 1
chr1_+_154193325 1.05 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
ubiquitin associated protein 2-like
chr20_-_3996036 1.05 ENST00000336095.6
ring finger protein 24
chr1_-_144932316 1.04 ENST00000313431.9
phosphodiesterase 4D interacting protein
chr2_-_136743039 1.04 ENST00000537273.1
aspartyl-tRNA synthetase
chr10_+_26986582 1.03 ENST00000376215.5
ENST00000376203.5
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr14_-_24658053 1.03 ENST00000354464.6
importin 4
chr8_-_90996837 1.01 ENST00000519426.1
ENST00000265433.3
nibrin
chr13_+_25875785 1.00 ENST00000381747.3
nucleoporin like 1
chr3_+_119187785 0.97 ENST00000295588.4
ENST00000476573.1
protein O-glucosyltransferase 1
chr7_-_27170352 0.97 ENST00000428284.2
ENST00000360046.5
homeobox A4
chr20_-_44540686 0.97 ENST00000477313.1
ENST00000542937.1
ENST00000372431.3
ENST00000354050.4
ENST00000420868.2
phospholipid transfer protein
chr1_-_144932014 0.97 ENST00000529945.1
phosphodiesterase 4D interacting protein
chr6_+_34204642 0.96 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr5_+_49962495 0.94 ENST00000515175.1
poly (ADP-ribose) polymerase family, member 8
chr3_-_195808952 0.93 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
transferrin receptor
chr17_-_2614927 0.93 ENST00000435359.1
clustered mitochondria (cluA/CLU1) homolog
chr1_+_113217073 0.92 ENST00000369645.1
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr6_+_30539153 0.92 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ATP-binding cassette, sub-family F (GCN20), member 1
chr12_+_7023735 0.91 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
enolase 2 (gamma, neuronal)
chr5_+_98109322 0.91 ENST00000513185.1
repulsive guidance molecule family member b
chr3_-_195808980 0.91 ENST00000360110.4
transferrin receptor
chr19_-_10530784 0.89 ENST00000593124.1
cell division cycle 37
chr18_+_43913919 0.89 ENST00000587853.1
ring finger protein 165
chr6_+_64282447 0.89 ENST00000370650.2
ENST00000578299.1
protein tyrosine phosphatase type IVA, member 1
chr17_-_36831156 0.88 ENST00000325814.5
chromosome 17 open reading frame 96
chr1_-_144932464 0.86 ENST00000479408.2
phosphodiesterase 4D interacting protein
chr17_+_64298944 0.83 ENST00000413366.3
protein kinase C, alpha
chr1_-_159894319 0.83 ENST00000320307.4
transgelin 2
chr1_-_241520525 0.83 ENST00000366565.1
regulator of G-protein signaling 7
chr3_-_50329835 0.81 ENST00000429673.2
interferon-related developmental regulator 2
chr15_+_62359175 0.80 ENST00000355522.5
C2 calcium-dependent domain containing 4A
chr5_+_49962772 0.80 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
poly (ADP-ribose) polymerase family, member 8
chr10_+_98592009 0.79 ENST00000540664.1
ENST00000371103.3
ligand dependent nuclear receptor corepressor
chr12_+_7023491 0.79 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr15_+_40453204 0.78 ENST00000287598.6
ENST00000412359.3
BUB1 mitotic checkpoint serine/threonine kinase B
chr2_-_235405168 0.78 ENST00000339728.3
ADP-ribosylation factor-like 4C
chr1_-_241520385 0.77 ENST00000366564.1
regulator of G-protein signaling 7
chr11_+_6624970 0.77 ENST00000420936.2
ENST00000528995.1
integrin-linked kinase
chr8_+_104426942 0.76 ENST00000297579.5
DDB1 and CUL4 associated factor 13
chr17_-_33469299 0.76 ENST00000586869.1
ENST00000360831.5
ENST00000442241.4
notchless homolog 1 (Drosophila)
chr10_+_72575643 0.76 ENST00000373202.3
sphingosine-1-phosphate lyase 1
chr19_+_50180317 0.76 ENST00000534465.1
protein arginine methyltransferase 1
chr5_+_34656569 0.75 ENST00000428746.2
retinoic acid induced 14
chr7_+_43152191 0.74 ENST00000395891.2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr6_+_108487245 0.74 ENST00000368986.4
nuclear receptor subfamily 2, group E, member 1
chr5_+_34656331 0.74 ENST00000265109.3
retinoic acid induced 14
chr1_-_8938736 0.73 ENST00000234590.4
enolase 1, (alpha)
chr7_-_105925367 0.73 ENST00000354289.4
nicotinamide phosphoribosyltransferase
chr6_-_43197189 0.73 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr19_+_50180507 0.72 ENST00000454376.2
ENST00000524771.1
protein arginine methyltransferase 1
chrX_+_77359671 0.71 ENST00000373316.4
phosphoglycerate kinase 1
chr6_+_64281906 0.70 ENST00000370651.3
protein tyrosine phosphatase type IVA, member 1
chr3_+_113666748 0.70 ENST00000330212.3
ENST00000498275.1
zinc finger, DHHC-type containing 23
chr19_+_50887585 0.70 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
polymerase (DNA directed), delta 1, catalytic subunit
chr10_-_31320860 0.69 ENST00000436087.2
ENST00000442986.1
ENST00000413025.1
ENST00000452305.1
zinc finger protein 438
chr19_+_10765003 0.69 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
interleukin enhancer binding factor 3, 90kDa
chr7_+_6048856 0.69 ENST00000223029.3
ENST00000400479.2
ENST00000395236.2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr8_-_132052458 0.68 ENST00000377928.3
adenylate cyclase 8 (brain)
chr9_+_35673853 0.68 ENST00000378357.4
carbonic anhydrase IX
chr14_-_53162361 0.68 ENST00000395686.3
ERO1-like (S. cerevisiae)
chr3_+_38179969 0.67 ENST00000396334.3
ENST00000417037.2
ENST00000424893.1
ENST00000495303.1
ENST00000443433.2
ENST00000421516.1
myeloid differentiation primary response 88
chr17_+_7338737 0.67 ENST00000323206.1
ENST00000396568.1
transmembrane protein 102
chr19_+_1205740 0.67 ENST00000326873.7
serine/threonine kinase 11
chr5_+_149546334 0.66 ENST00000231656.8
caudal type homeobox 1
chr19_+_6739662 0.66 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
thyroid hormone receptor interactor 10
chr11_+_6625046 0.66 ENST00000396751.2
integrin-linked kinase
chr11_+_34127142 0.66 ENST00000257829.3
ENST00000531159.2
N-acetyltransferase 10 (GCN5-related)
chr5_-_9546180 0.66 ENST00000382496.5
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr7_+_100464760 0.65 ENST00000200457.4
thyroid hormone receptor interactor 6
chr3_-_185826855 0.65 ENST00000306376.5
ets variant 5
chr17_-_48474828 0.65 ENST00000576448.1
ENST00000225972.7
leucine rich repeat containing 59
chr7_-_92465868 0.64 ENST00000424848.2
cyclin-dependent kinase 6
chr11_+_6624955 0.64 ENST00000299421.4
ENST00000537806.1
integrin-linked kinase
chr14_+_74004051 0.63 ENST00000557556.1
acyl-CoA thioesterase 1
chr19_-_16682987 0.63 ENST00000431408.1
ENST00000436553.2
ENST00000595753.1
solute carrier family 35, member E1
chr1_+_40420802 0.63 ENST00000372811.5
ENST00000420632.2
ENST00000434861.1
ENST00000372809.5
major facilitator superfamily domain containing 2A
chr19_+_40476912 0.62 ENST00000157812.2
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr19_-_5720248 0.62 ENST00000360614.3
lon peptidase 1, mitochondrial
chr11_-_76381781 0.60 ENST00000260061.5
ENST00000404995.1
leucine rich repeat containing 32
chr5_-_171881491 0.60 ENST00000311601.5
SH3 and PX domains 2B
chr5_+_70883117 0.60 ENST00000340941.6
methylcrotonoyl-CoA carboxylase 2 (beta)
chr6_-_31869769 0.59 ENST00000375527.2
zinc finger and BTB domain containing 12
chr9_-_73029540 0.59 ENST00000377126.2
Kruppel-like factor 9
chr3_-_50329990 0.59 ENST00000417626.2
interferon-related developmental regulator 2
chr9_-_2844058 0.59 ENST00000397885.2
KIAA0020
chr18_+_33877654 0.59 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
formin homology 2 domain containing 3
chr19_-_45657028 0.59 ENST00000429338.1
ENST00000589776.1
NTPase, KAP family P-loop domain containing 1
chr17_-_28257080 0.59 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
slingshot protein phosphatase 2
chr2_+_55459808 0.58 ENST00000404735.1
ribosomal protein S27a
chr1_+_19578033 0.58 ENST00000330263.4
mRNA turnover 4 homolog (S. cerevisiae)
chr3_-_57583185 0.57 ENST00000463880.1
ADP-ribosylation factor 4
chr19_-_5719860 0.57 ENST00000590729.1
lon peptidase 1, mitochondrial
chr18_-_33077556 0.57 ENST00000589273.1
ENST00000586489.1
INO80 complex subunit C
chr8_+_41435696 0.57 ENST00000396987.3
ENST00000519853.1
1-acylglycerol-3-phosphate O-acyltransferase 6
chr5_-_114961673 0.57 ENST00000333314.3
TMED7-TICAM2 readthrough
chr11_+_62623512 0.56 ENST00000377892.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr16_-_54963026 0.56 ENST00000560208.1
ENST00000557792.1
colorectal neoplasia differentially expressed (non-protein coding)
chr12_+_6977258 0.56 ENST00000488464.2
ENST00000535434.1
ENST00000493987.1
triosephosphate isomerase 1
chr19_+_10764937 0.56 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
interleukin enhancer binding factor 3, 90kDa
chr5_+_143584814 0.56 ENST00000507359.3
potassium channel tetramerization domain containing 16
chr7_-_2354099 0.56 ENST00000222990.3
sorting nexin 8
chr12_+_54519842 0.56 ENST00000508564.1
RP11-834C11.4
chr3_+_100428268 0.56 ENST00000240851.4
TRK-fused gene
chr1_-_111991850 0.55 ENST00000411751.2
WD repeat domain 77
chr1_-_246729544 0.55 ENST00000544618.1
ENST00000366514.4
transcription factor B2, mitochondrial
chr1_-_223537475 0.55 ENST00000344029.6
ENST00000494793.2
ENST00000366878.4
ENST00000366877.3
sushi domain containing 4
chr10_-_44070016 0.55 ENST00000374446.2
ENST00000426961.1
ENST00000535642.1
zinc finger protein 239
chr19_-_663277 0.55 ENST00000292363.5
ring finger protein 126
chr9_-_35732362 0.55 ENST00000314888.9
ENST00000540444.1
talin 1
chr7_-_56119156 0.55 ENST00000421312.1
ENST00000416592.1
phosphoserine phosphatase
chr12_-_31478428 0.54 ENST00000543615.1
family with sequence similarity 60, member A
chr19_+_40477062 0.54 ENST00000455878.2
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr19_-_5720123 0.54 ENST00000587365.1
ENST00000585374.1
ENST00000593119.1
lon peptidase 1, mitochondrial
chr17_-_76836729 0.54 ENST00000587783.1
ENST00000542802.3
ENST00000586531.1
ENST00000589424.1
ENST00000590546.2
ubiquitin specific peptidase 36
chr19_+_50180409 0.54 ENST00000391851.4
protein arginine methyltransferase 1
chr5_+_68530668 0.54 ENST00000506563.1
cyclin-dependent kinase 7
chr8_-_70745575 0.53 ENST00000524945.1
solute carrier organic anion transporter family, member 5A1
chr11_-_64014379 0.53 ENST00000309318.3
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr4_-_39529049 0.53 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
UDP-glucose 6-dehydrogenase
chr3_+_100428316 0.53 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TRK-fused gene
chr1_+_45805342 0.53 ENST00000372090.5
target of EGR1, member 1 (nuclear)
chr7_-_105925558 0.52 ENST00000222553.3
nicotinamide phosphoribosyltransferase
chr17_-_34890665 0.52 ENST00000586007.1
myosin XIX
chr5_+_133861790 0.51 ENST00000395003.1
jade family PHD finger 2
chr16_+_2098003 0.51 ENST00000439673.2
ENST00000350773.4
tuberous sclerosis 2
chr6_+_151187615 0.51 ENST00000441122.1
ENST00000423867.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr15_+_45722727 0.51 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
chromosome 15 open reading frame 48
chr11_+_125462690 0.51 ENST00000392708.4
ENST00000529196.1
ENST00000531491.1
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr1_+_11333245 0.50 ENST00000376810.5
UbiA prenyltransferase domain containing 1
chr9_+_112542572 0.50 ENST00000374530.3
PALM2-AKAP2 readthrough
chr3_-_71632894 0.50 ENST00000493089.1
forkhead box P1
chr17_+_41132564 0.50 ENST00000361677.1
ENST00000589705.1
RUN domain containing 1
chr20_+_825275 0.50 ENST00000541082.1
family with sequence similarity 110, member A
chr6_+_126070726 0.50 ENST00000368364.3
hes-related family bHLH transcription factor with YRPW motif 2
chr17_-_42143963 0.49 ENST00000585388.1
ENST00000293406.3
LSM12 homolog (S. cerevisiae)
chr2_+_68384976 0.49 ENST00000263657.2
partner of NOB1 homolog (S. cerevisiae)
chr6_+_33257427 0.49 ENST00000463584.1
prefoldin subunit 6
chr9_-_123639304 0.49 ENST00000436309.1
PHD finger protein 19
chr5_+_173315283 0.49 ENST00000265085.5
cytoplasmic polyadenylation element binding protein 4
chr9_+_2622085 0.49 ENST00000382099.2
very low density lipoprotein receptor

Network of associatons between targets according to the STRING database.

First level regulatory network of ARNT

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.0 GO:0034226 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
2.1 10.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.8 3.4 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.7 2.7 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.6 1.9 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.6 1.7 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.6 1.7 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.5 2.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.5 5.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.5 1.4 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.4 1.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.4 2.9 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.4 1.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.4 2.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.4 1.8 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.3 1.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.3 1.8 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.3 1.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.3 0.8 GO:0035408 histone H3-T6 phosphorylation(GO:0035408) dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.3 1.9 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.3 1.9 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.3 1.3 GO:0015692 lead ion transport(GO:0015692)
0.3 0.5 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
0.2 0.7 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 1.0 GO:0042360 vitamin E metabolic process(GO:0042360)
0.2 0.9 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 0.7 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.2 1.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.2 1.1 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 0.7 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.2 0.9 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 1.4 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 0.6 GO:0071336 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.2 0.8 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.2 1.0 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.2 0.6 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.2 0.6 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 1.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.2 1.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.2 1.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 0.5 GO:0043686 co-translational protein modification(GO:0043686)
0.2 1.8 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) response to UV-A(GO:0070141)
0.2 0.5 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2 0.3 GO:0003358 noradrenergic neuron development(GO:0003358)
0.2 0.6 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 0.9 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.4 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 2.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 1.0 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 0.7 GO:0070384 growth plate cartilage chondrocyte growth(GO:0003430) Harderian gland development(GO:0070384)
0.1 0.6 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.7 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 1.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.8 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.7 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.4 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.4 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 1.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.5 GO:0009233 menaquinone metabolic process(GO:0009233)
0.1 0.4 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.1 0.4 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 1.0 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 0.3 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.5 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 0.6 GO:0060356 leucine import(GO:0060356)
0.1 1.9 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.4 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 0.8 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.3 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.7 GO:0071233 cellular response to leucine(GO:0071233)
0.1 1.1 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.4 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.3 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.1 0.3 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.7 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 1.8 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 0.1 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.1 0.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.9 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 3.9 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.4 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.3 GO:0015709 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 1.7 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 0.5 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1 0.6 GO:0051414 response to cortisol(GO:0051414)
0.1 1.0 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 1.8 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.9 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.7 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.5 GO:0034436 glycoprotein transport(GO:0034436)
0.1 2.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 2.1 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.1 0.5 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.3 GO:0032811 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.6 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.1 0.4 GO:0060992 response to fungicide(GO:0060992)
0.1 1.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 0.8 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 1.0 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.3 GO:0072069 thick ascending limb development(GO:0072023) DCT cell differentiation(GO:0072069) metanephric thick ascending limb development(GO:0072233) metanephric DCT cell differentiation(GO:0072240)
0.1 0.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.6 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.7 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 0.6 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.7 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.2 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.1 0.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.2 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.3 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 1.1 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.6 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.3 GO:0035519 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.1 0.8 GO:0001553 luteinization(GO:0001553)
0.1 1.1 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.1 1.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.4 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.2 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.0 0.2 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.6 GO:0032310 prostaglandin secretion(GO:0032310)
0.0 0.5 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.8 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.0 0.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 1.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 1.0 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.9 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0 0.7 GO:0040016 embryonic cleavage(GO:0040016)
0.0 1.5 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.3 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.3 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.3 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.1 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.3 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.2 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.3 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.3 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.2 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.3 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.6 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.7 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 1.1 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.6 GO:0045176 apical protein localization(GO:0045176)
0.0 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.3 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 1.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.8 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.5 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 2.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 1.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.3 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.0 0.8 GO:0046135 pyrimidine nucleoside catabolic process(GO:0046135)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.0 GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.1 GO:0018194 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.2 GO:0060699 regulation of endoribonuclease activity(GO:0060699) regulation of ribonuclease activity(GO:0060700)
0.0 0.5 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 1.1 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.0 0.2 GO:0045007 depurination(GO:0045007)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.7 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 1.6 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 1.3 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 1.6 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.5 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.8 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:1905073 negative regulation of low-density lipoprotein particle clearance(GO:0010989) positive regulation of relaxation of muscle(GO:1901079) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 1.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.1 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 0.3 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.6 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.0 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.0 0.6 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.3 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.0 0.2 GO:1901070 guanosine-containing compound biosynthetic process(GO:1901070)
0.0 0.5 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 1.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.6 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 1.1 GO:0048477 oogenesis(GO:0048477)
0.0 0.4 GO:0031648 protein destabilization(GO:0031648)
0.0 0.3 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.4 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 1.1 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 1.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.3 1.4 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.3 1.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.3 1.3 GO:0070826 paraferritin complex(GO:0070826)
0.2 0.9 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 2.1 GO:0030870 Mre11 complex(GO:0030870)
0.2 1.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 1.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 1.1 GO:0070876 SOSS complex(GO:0070876)
0.2 1.0 GO:0036398 TCR signalosome(GO:0036398)
0.2 0.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 0.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 0.5 GO:0030689 Noc complex(GO:0030689)
0.2 0.9 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 2.8 GO:0034709 methylosome(GO:0034709)
0.1 11.8 GO:0015030 Cajal body(GO:0015030)
0.1 0.4 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.5 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.4 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 1.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.6 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 0.7 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.9 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.7 GO:0070545 PeBoW complex(GO:0070545)
0.1 1.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.4 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 1.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 1.1 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 3.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.4 GO:0097452 GAIT complex(GO:0097452)
0.1 1.6 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 0.6 GO:0000322 storage vacuole(GO:0000322)
0.1 0.8 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.7 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 1.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 2.0 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 1.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 1.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0030686 90S preribosome(GO:0030686)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.7 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 1.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 0.6 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.7 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.5 GO:0000346 transcription export complex(GO:0000346)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.6 GO:0030904 retromer complex(GO:0030904)
0.0 0.4 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.3 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0045120 pronucleus(GO:0045120)
0.0 3.1 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.4 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.7 GO:0008859 exoribonuclease II activity(GO:0008859)
2.3 9.0 GO:0005287 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.9 4.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.6 1.8 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.6 1.7 GO:0070362 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.5 3.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 1.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.3 3.1 GO:0043426 MRF binding(GO:0043426)
0.3 1.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 1.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.3 1.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.3 1.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.3 2.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.3 2.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 1.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.3 1.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 0.8 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.3 1.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 1.8 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.3 1.3 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.3 1.5 GO:0034046 poly(G) binding(GO:0034046)
0.2 1.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 0.6 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 1.7 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.0 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.2 0.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 0.6 GO:0032427 GBD domain binding(GO:0032427)
0.2 1.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 0.7 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 0.7 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 0.5 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.2 0.5 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.2 0.6 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.4 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.6 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 0.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 1.1 GO:0043559 insulin binding(GO:0043559)
0.1 0.4 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.5 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.6 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 1.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.4 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 1.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.3 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.2 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.5 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 0.4 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 0.3 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.5 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.4 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.9 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.1 1.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.3 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 1.4 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.7 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 0.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.6 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.3 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.4 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 3.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.4 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 3.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 1.4 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.2 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 2.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.7 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 1.4 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.4 GO:0005112 Notch binding(GO:0005112)
0.1 2.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 1.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.3 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 1.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 1.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.2 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.2 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.9 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.8 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.3 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.8 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0005536 glucose binding(GO:0005536)
0.0 0.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 2.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 1.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.4 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.7 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0004673 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.0 0.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.3 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.8 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.5 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 16.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.7 PID IL5 PATHWAY IL5-mediated signaling events
0.1 4.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 8.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 4.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 4.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.2 9.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 2.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 14.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 6.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.1 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.1 0.9 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.1 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.6 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 0.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.3 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 2.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.8 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 2.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 2.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.9 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.8 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.3 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.6 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 2.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters