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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CAGUGCA

Z-value: 0.62

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miRNA associated with seed CAGUGCA

NamemiRBASE accession
hsa-miR-148a-3p
MIMAT0000243
hsa-miR-148b-3p
MIMAT0000759
hsa-miR-152-3p
MIMAT0000438

Activity profile of CAGUGCA motif

Sorted Z-values of CAGUGCA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_39317868 2.66 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr3_-_64211112 2.63 ENST00000295902.6
PRICKLE2
prickle homolog 2 (Drosophila)
chr12_+_27396901 1.91 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr8_-_22550815 1.82 ENST00000317216.2
EGR3
early growth response 3
chr1_+_78470530 1.74 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr9_-_140196703 1.65 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr8_-_93115445 1.61 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_+_55524085 1.47 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr18_+_8717369 1.46 ENST00000359865.3
ENST00000400050.3
ENST00000306285.7
SOGA2
SOGA family member 2
chr21_-_44846999 1.44 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr10_-_33623564 1.41 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr7_-_15726296 1.35 ENST00000262041.5
MEOX2
mesenchyme homeobox 2
chr5_-_172198190 1.30 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr17_+_47865917 1.25 ENST00000259021.4
ENST00000454930.2
ENST00000509773.1
ENST00000510819.1
ENST00000424009.2
KAT7
K(lysine) acetyltransferase 7
chr20_+_34700333 1.23 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr6_-_16761678 1.20 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr6_+_15246501 1.20 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr7_+_114562172 1.16 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chr6_-_111136513 1.14 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr11_+_59522532 1.11 ENST00000337979.4
ENST00000535361.1
STX3
syntaxin 3
chr6_-_30585009 1.10 ENST00000376511.2
PPP1R10
protein phosphatase 1, regulatory subunit 10
chr15_+_41221536 1.08 ENST00000249749.5
DLL4
delta-like 4 (Drosophila)
chr7_+_116312411 1.00 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr12_+_79258547 0.99 ENST00000457153.2
SYT1
synaptotagmin I
chrX_+_77166172 0.95 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr18_-_29264669 0.94 ENST00000306851.5
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr17_+_79373540 0.91 ENST00000307745.7
RP11-1055B8.7
BAH and coiled-coil domain-containing protein 1
chr2_+_46524537 0.90 ENST00000263734.3
EPAS1
endothelial PAS domain protein 1
chr3_+_194406603 0.87 ENST00000329759.4
FAM43A
family with sequence similarity 43, member A
chr5_-_90679145 0.84 ENST00000265138.3
ARRDC3
arrestin domain containing 3
chr6_+_161412759 0.83 ENST00000366919.2
ENST00000392142.4
ENST00000366920.2
ENST00000348824.7
MAP3K4
mitogen-activated protein kinase kinase kinase 4
chr14_+_53019822 0.80 ENST00000321662.6
GPR137C
G protein-coupled receptor 137C
chr20_+_11871371 0.80 ENST00000254977.3
BTBD3
BTB (POZ) domain containing 3
chr19_+_45973120 0.79 ENST00000592811.1
ENST00000586615.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chrX_+_118108571 0.78 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr1_+_12227035 0.75 ENST00000376259.3
ENST00000536782.1
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr6_+_143929307 0.72 ENST00000427704.2
ENST00000305766.6
PHACTR2
phosphatase and actin regulator 2
chr13_-_79233314 0.67 ENST00000282003.6
RNF219
ring finger protein 219
chr5_+_78532003 0.66 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr3_+_43328004 0.66 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNRK
SNF related kinase
chr5_+_122110691 0.65 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2
sorting nexin 2
chrX_-_74376108 0.64 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr17_+_30813576 0.62 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr3_-_141868357 0.61 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr7_-_86688990 0.59 ENST00000450689.2
KIAA1324L
KIAA1324-like
chr14_-_91526922 0.58 ENST00000418736.2
ENST00000261991.3
RPS6KA5
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr5_+_176560742 0.58 ENST00000439151.2
NSD1
nuclear receptor binding SET domain protein 1
chr17_+_5031687 0.56 ENST00000250066.6
ENST00000304328.5
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr6_+_107811162 0.56 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr1_+_94883931 0.55 ENST00000394233.2
ENST00000454898.2
ENST00000536817.1
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr19_+_13049413 0.54 ENST00000316448.5
ENST00000588454.1
CALR
calreticulin
chr5_+_112849373 0.54 ENST00000161863.4
ENST00000515883.1
YTHDC2
YTH domain containing 2
chr17_-_66287257 0.53 ENST00000327268.4
SLC16A6
solute carrier family 16, member 6
chr2_+_33359687 0.53 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr6_-_112575912 0.53 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr10_-_52383644 0.53 ENST00000361781.2
SGMS1
sphingomyelin synthase 1
chr8_-_9008206 0.53 ENST00000310455.3
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr16_-_30107491 0.52 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3
yippee-like 3 (Drosophila)
chr18_+_60190226 0.52 ENST00000269499.5
ZCCHC2
zinc finger, CCHC domain containing 2
chr10_+_89622870 0.51 ENST00000371953.3
PTEN
phosphatase and tensin homolog
chr13_-_107187462 0.49 ENST00000245323.4
EFNB2
ephrin-B2
chr11_+_73019282 0.48 ENST00000263674.3
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr7_-_6312206 0.48 ENST00000350796.3
CYTH3
cytohesin 3
chr4_-_42659102 0.48 ENST00000264449.10
ENST00000510289.1
ENST00000381668.5
ATP8A1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr18_-_72921303 0.47 ENST00000322342.3
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr20_-_47444420 0.47 ENST00000371941.3
ENST00000396220.1
PREX1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr2_+_56411131 0.46 ENST00000407595.2
CCDC85A
coiled-coil domain containing 85A
chr13_-_21476900 0.44 ENST00000400602.2
ENST00000255305.6
XPO4
exportin 4
chr17_-_16118835 0.44 ENST00000582357.1
ENST00000436828.1
ENST00000411510.1
ENST00000268712.3
NCOR1
nuclear receptor corepressor 1
chr16_+_53088885 0.42 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr11_+_123396528 0.41 ENST00000322282.7
ENST00000529750.1
GRAMD1B
GRAM domain containing 1B
chr3_+_138066539 0.40 ENST00000289104.4
MRAS
muscle RAS oncogene homolog
chr2_+_169312350 0.40 ENST00000305747.6
CERS6
ceramide synthase 6
chr20_+_1246908 0.39 ENST00000381873.3
ENST00000381867.1
SNPH
syntaphilin
chr1_-_173991434 0.39 ENST00000367696.2
RC3H1
ring finger and CCCH-type domains 1
chr1_+_93913713 0.39 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr19_+_11200038 0.39 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
LDLR
low density lipoprotein receptor
chr8_-_66754172 0.39 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr1_-_22109682 0.38 ENST00000400301.1
ENST00000532737.1
USP48
ubiquitin specific peptidase 48
chr20_+_4666882 0.38 ENST00000379440.4
ENST00000430350.2
PRNP
prion protein
chr6_-_79787902 0.38 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr12_-_54813229 0.38 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_-_205649580 0.38 ENST00000367145.3
SLC45A3
solute carrier family 45, member 3
chr11_-_10315741 0.37 ENST00000256190.8
SBF2
SET binding factor 2
chr2_-_160472952 0.37 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr15_-_52030293 0.37 ENST00000560491.1
ENST00000267838.3
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr3_-_197476560 0.36 ENST00000273582.5
KIAA0226
KIAA0226
chrX_-_109561294 0.36 ENST00000372059.2
ENST00000262844.5
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr8_+_29952914 0.36 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr15_-_49338748 0.35 ENST00000559471.1
SECISBP2L
SECIS binding protein 2-like
chr1_+_33005020 0.34 ENST00000373510.4
ENST00000316459.4
ZBTB8A
zinc finger and BTB domain containing 8A
chr16_-_23521710 0.34 ENST00000562117.1
ENST00000567468.1
ENST00000562944.1
ENST00000309859.4
GGA2
golgi-associated, gamma adaptin ear containing, ARF binding protein 2
chr1_-_154928562 0.33 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr2_+_86947296 0.33 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr8_-_81787006 0.33 ENST00000327835.3
ZNF704
zinc finger protein 704
chr11_-_46940074 0.32 ENST00000378623.1
ENST00000534404.1
LRP4
low density lipoprotein receptor-related protein 4
chr11_+_120207787 0.32 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr22_+_40573921 0.32 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr17_+_28705921 0.32 ENST00000225719.4
CPD
carboxypeptidase D
chr15_+_51200859 0.31 ENST00000261842.5
AP4E1
adaptor-related protein complex 4, epsilon 1 subunit
chr15_-_31283798 0.31 ENST00000435680.1
ENST00000425768.1
MTMR10
myotubularin related protein 10
chr21_-_34100244 0.31 ENST00000382491.3
ENST00000357345.3
ENST00000429236.1
SYNJ1
synaptojanin 1
chr20_-_31071239 0.31 ENST00000359676.5
C20orf112
chromosome 20 open reading frame 112
chr9_+_91003271 0.30 ENST00000375859.3
ENST00000541629.1
SPIN1
spindlin 1
chr2_-_105946491 0.30 ENST00000393359.2
TGFBRAP1
transforming growth factor, beta receptor associated protein 1
chr3_+_107241783 0.30 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
BBX
bobby sox homolog (Drosophila)
chr1_+_66797687 0.29 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr11_-_94964354 0.29 ENST00000536441.1
SESN3
sestrin 3
chr16_+_58059470 0.29 ENST00000219271.3
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr12_-_8088871 0.28 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr16_-_18812746 0.28 ENST00000546206.2
ENST00000562819.1
ENST00000562234.2
ENST00000304414.7
ENST00000567078.2
ARL6IP1
RP11-1035H13.3
ADP-ribosylation factor-like 6 interacting protein 1
Uncharacterized protein
chr14_-_35182994 0.27 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr17_-_76356148 0.27 ENST00000587578.1
ENST00000330871.2
SOCS3
suppressor of cytokine signaling 3
chrX_+_40440146 0.26 ENST00000535539.1
ENST00000378438.4
ENST00000436783.1
ENST00000544975.1
ENST00000535777.1
ENST00000447485.1
ENST00000423649.1
ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
chr12_+_111843749 0.26 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr3_-_114790179 0.26 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr11_-_64570706 0.25 ENST00000294066.2
ENST00000377350.3
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr11_+_12695944 0.25 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr5_-_39074479 0.24 ENST00000514735.1
ENST00000296782.5
ENST00000357387.3
RICTOR
RPTOR independent companion of MTOR, complex 2
chr1_+_200708671 0.24 ENST00000358823.2
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr4_+_170541660 0.24 ENST00000513761.1
ENST00000347613.4
CLCN3
chloride channel, voltage-sensitive 3
chr8_+_70378852 0.24 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1
sulfatase 1
chr18_-_53255766 0.24 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr2_-_164592497 0.23 ENST00000333129.3
ENST00000409634.1
FIGN
fidgetin
chr9_-_36400213 0.23 ENST00000259605.6
ENST00000353739.4
RNF38
ring finger protein 38
chr3_-_72496035 0.23 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr2_-_101767715 0.23 ENST00000376840.4
ENST00000409318.1
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chrX_+_21958674 0.22 ENST00000404933.2
SMS
spermine synthase
chr9_-_107690420 0.22 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr2_-_180129484 0.22 ENST00000428443.3
SESTD1
SEC14 and spectrin domains 1
chr3_-_105587879 0.21 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr17_-_58469474 0.21 ENST00000300896.4
USP32
ubiquitin specific peptidase 32
chr7_+_77325738 0.21 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr21_+_35445827 0.21 ENST00000608209.1
ENST00000381151.3
SLC5A3
SLC5A3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr18_+_59854480 0.21 ENST00000256858.6
ENST00000398130.2
KIAA1468
KIAA1468
chr21_-_47706205 0.20 ENST00000397708.1
MCM3AP
minichromosome maintenance complex component 3 associated protein
chr6_+_152011628 0.20 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr6_+_35310312 0.20 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD
peroxisome proliferator-activated receptor delta
chr12_+_104324112 0.20 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr5_+_118407053 0.20 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr20_-_60640866 0.19 ENST00000252996.4
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr20_+_57267669 0.19 ENST00000356091.6
NPEPL1
aminopeptidase-like 1
chr5_-_138775177 0.19 ENST00000302060.5
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr1_+_244214577 0.19 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr7_-_138666053 0.19 ENST00000440172.1
ENST00000422774.1
KIAA1549
KIAA1549
chr10_+_47894023 0.19 ENST00000358474.5
FAM21B
family with sequence similarity 21, member B
chr11_-_110583451 0.18 ENST00000260283.4
ENST00000528829.1
ARHGAP20
Rho GTPase activating protein 20
chr16_-_70719925 0.18 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr13_+_113344542 0.18 ENST00000487903.1
ENST00000375630.2
ENST00000375645.3
ENST00000283558.8
ATP11A
ATPase, class VI, type 11A
chr1_-_153895377 0.18 ENST00000368655.4
GATAD2B
GATA zinc finger domain containing 2B
chr17_-_27224621 0.18 ENST00000394906.2
ENST00000585169.1
ENST00000394908.4
FLOT2
flotillin 2
chr1_-_225615599 0.18 ENST00000421383.1
ENST00000272163.4
LBR
lamin B receptor
chrX_-_24690771 0.18 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr1_+_70671363 0.18 ENST00000370951.1
ENST00000370950.3
ENST00000405432.1
ENST00000454435.2
SRSF11
serine/arginine-rich splicing factor 11
chr13_+_28813645 0.18 ENST00000282391.5
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr19_-_10305752 0.18 ENST00000540357.1
ENST00000359526.4
ENST00000340748.4
DNMT1
DNA (cytosine-5-)-methyltransferase 1
chr1_+_203595903 0.17 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chrX_-_18372792 0.17 ENST00000251900.4
SCML2
sex comb on midleg-like 2 (Drosophila)
chr6_+_17281573 0.17 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr6_+_84569359 0.17 ENST00000369681.5
ENST00000369679.4
CYB5R4
cytochrome b5 reductase 4
chr18_-_12657988 0.17 ENST00000410092.3
ENST00000409402.4
SPIRE1
spire-type actin nucleation factor 1
chr19_-_40324255 0.16 ENST00000593685.1
ENST00000600611.1
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr20_+_3776371 0.16 ENST00000245960.5
CDC25B
cell division cycle 25B
chr20_-_5591626 0.16 ENST00000379019.4
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr1_-_52344471 0.15 ENST00000352171.7
ENST00000354831.7
NRD1
nardilysin (N-arginine dibasic convertase)
chr1_-_214724566 0.15 ENST00000366956.5
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr11_-_45687128 0.15 ENST00000308064.2
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr1_-_179198702 0.15 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr4_+_153701081 0.15 ENST00000451320.2
ENST00000429148.2
ENST00000353617.2
ENST00000405727.2
ENST00000356064.3
ARFIP1
ADP-ribosylation factor interacting protein 1
chr1_-_8086343 0.15 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERRFI1
ERBB receptor feedback inhibitor 1
chr7_-_123389104 0.15 ENST00000223023.4
WASL
Wiskott-Aldrich syndrome-like
chr2_-_183903133 0.15 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr14_-_39901618 0.15 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr6_-_116601044 0.14 ENST00000368608.3
TSPYL1
TSPY-like 1
chr12_-_8025442 0.14 ENST00000340749.5
ENST00000535295.1
ENST00000539234.1
SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr7_-_105517021 0.14 ENST00000318724.4
ENST00000419735.3
ATXN7L1
ataxin 7-like 1
chr16_-_85045131 0.14 ENST00000313732.4
ZDHHC7
zinc finger, DHHC-type containing 7
chr15_-_73925651 0.14 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
NPTN
neuroplastin
chr17_-_2304365 0.14 ENST00000575394.1
ENST00000174618.4
MNT
MAX network transcriptional repressor
chr22_-_21213029 0.14 ENST00000572273.1
ENST00000255882.6
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr10_+_46222648 0.14 ENST00000336378.4
ENST00000540872.1
ENST00000537517.1
ENST00000374362.2
ENST00000359860.4
ENST00000420848.1
FAM21C
family with sequence similarity 21, member C
chr16_+_24741013 0.13 ENST00000315183.7
ENST00000395799.3
TNRC6A
trinucleotide repeat containing 6A
chr1_-_46598284 0.13 ENST00000423209.1
ENST00000262741.5
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr6_+_64345698 0.13 ENST00000506783.1
ENST00000481385.2
ENST00000515594.1
ENST00000494284.2
ENST00000262043.3
PHF3
PHD finger protein 3
chr7_-_14029515 0.13 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1
ets variant 1
chr12_+_109915179 0.13 ENST00000434735.2
UBE3B
ubiquitin protein ligase E3B
chr7_-_105029329 0.13 ENST00000393651.3
ENST00000460391.1
SRPK2
SRSF protein kinase 2
chrX_+_12993202 0.13 ENST00000451311.2
ENST00000380636.1
TMSB4X
thymosin beta 4, X-linked
chr2_+_134877740 0.12 ENST00000409645.1
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr15_-_56535464 0.12 ENST00000559447.2
ENST00000422057.1
ENST00000317318.6
ENST00000423270.1
RFX7
regulatory factor X, 7
chr10_+_102295616 0.12 ENST00000299163.6
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr7_-_112579869 0.12 ENST00000297145.4
C7orf60
chromosome 7 open reading frame 60
chr5_+_134181625 0.12 ENST00000394976.3
C5orf24
chromosome 5 open reading frame 24
chrX_+_109246285 0.12 ENST00000372073.1
ENST00000372068.2
ENST00000288381.4
TMEM164
transmembrane protein 164
chr19_+_8483272 0.12 ENST00000602117.1
MARCH2
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr6_+_147525541 0.12 ENST00000367481.3
ENST00000546097.1
STXBP5
syntaxin binding protein 5 (tomosyn)
chr4_+_71768043 0.11 ENST00000502869.1
ENST00000309395.2
ENST00000396051.2
MOB1B
MOB kinase activator 1B
chr17_-_27230035 0.11 ENST00000378895.4
ENST00000394901.3
DHRS13
dehydrogenase/reductase (SDR family) member 13
chrX_-_134049262 0.11 ENST00000370783.3
MOSPD1
motile sperm domain containing 1
chr15_+_76352178 0.11 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27

Network of associatons between targets according to the STRING database.

First level regulatory network of CAGUGCA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.5 1.5 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.4 1.3 GO:0072720 response to dithiothreitol(GO:0072720)
0.3 1.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.3 0.9 GO:0071284 cellular response to lead ion(GO:0071284)
0.3 1.4 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.3 1.4 GO:1905040 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.3 0.8 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.3 1.1 GO:0072554 blood vessel lumenization(GO:0072554)
0.2 1.4 GO:0001757 somite specification(GO:0001757)
0.2 1.8 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.2 0.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.8 GO:0007538 primary sex determination(GO:0007538)
0.2 0.6 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2 1.0 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 1.7 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 1.1 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.1 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1 0.5 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.5 GO:1903984 negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.4 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.5 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.6 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.9 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.3 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 0.4 GO:1905167 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.4 GO:1990535 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.1 0.5 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 1.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.3 GO:1904978 regulation of endosome organization(GO:1904978)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.1 0.6 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.1 0.3 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 1.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.2 GO:2000283 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.4 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.2 GO:0015917 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.6 GO:0015886 heme transport(GO:0015886)
0.0 0.5 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.4 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.5 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.0 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.0 0.1 GO:0090155 negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 1.4 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.8 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.1 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0061054 Spemann organizer formation(GO:0060061) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.0 1.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 1.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0070649 cleavage furrow formation(GO:0036089) polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.3 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) regulation of genetic imprinting(GO:2000653)
0.0 0.4 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 1.8 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0060751 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.2 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.2 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 2.4 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.6 GO:0090102 cochlea development(GO:0090102)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.0 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.1 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.0 GO:0097498 endothelial tube lumen extension(GO:0097498)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.2 1.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 1.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 1.8 GO:0097443 sorting endosome(GO:0097443)
0.2 0.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 1.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.7 GO:0043196 varicosity(GO:0043196)
0.1 0.5 GO:0042587 glycogen granule(GO:0042587)
0.1 0.7 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.5 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.1 0.5 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.3 GO:0033263 CORVET complex(GO:0033263)
0.1 0.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.3 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0031251 PAN complex(GO:0031251)
0.0 0.5 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.5 GO:0016600 flotillin complex(GO:0016600)
0.0 1.5 GO:0042629 mast cell granule(GO:0042629)
0.0 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0019034 viral replication complex(GO:0019034)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 2.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 0.9 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 0.6 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 0.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2 1.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.7 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.5 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.4 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.5 GO:0050436 microfibril binding(GO:0050436)
0.1 0.5 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 1.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.2 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 1.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.2 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.5 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.4 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.4 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.5 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 1.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.2 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.6 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 1.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.4 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.0 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.4 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 1.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.9 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.2 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK