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Inflammatory response time course, HUVEC (Wada et al., 2009)
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Results for MSX1
Z-value: 0.47
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Transcription factors associated with MSX1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MSX1 | hg19_v2_chr4_+_4861385_4861398 | -0.01 | 9.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr21_+_43619796 Show fit | 1.06 |
ENST00000398457.2
|
ATP-binding cassette, sub-family G (WHITE), member 1 |
|
| chr10_-_101380121 Show fit | 0.89 |
ENST00000370495.4
|
solute carrier family 25 (mitochondrial iron transporter), member 28 |
|
| chr6_+_28249299 Show fit | 0.85 |
ENST00000405948.2
|
piggyBac transposable element derived 1 |
|
| chr6_+_28249332 Show fit | 0.85 |
ENST00000259883.3
|
piggyBac transposable element derived 1 |
|
| chr5_+_121647386 Show fit | 0.73 |
ENST00000542191.1
ENST00000506272.1 ENST00000508681.1 ENST00000509154.2 |
synuclein, alpha interacting protein |
|
| chr22_+_41697520 Show fit | 0.58 |
ENST00000352645.4
|
zinc finger CCCH-type containing 7B |
|
| chr12_-_52911718 Show fit | 0.57 |
ENST00000548409.1
|
keratin 5 |
|
| chr19_+_3762645 Show fit | 0.53 |
ENST00000330133.4
|
mitochondrial ribosomal protein L54 |
|
| chr17_-_37934466 Show fit | 0.53 |
ENST00000583368.1
|
IKAROS family zinc finger 3 (Aiolos) |
|
| chr9_+_115913222 Show fit | 0.52 |
ENST00000259392.3
|
solute carrier family 31 (copper transporter), member 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of MSX1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.1 | GO:0055099 | detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099) |
| 0.1 | 1.1 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.3 | 0.9 | GO:0048250 | mitochondrial iron ion transport(GO:0048250) |
| 0.0 | 0.7 | GO:0090083 | regulation of inclusion body assembly(GO:0090083) |
| 0.1 | 0.6 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.0 | 0.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 0.5 | GO:1902748 | positive regulation of lens fiber cell differentiation(GO:1902748) |
| 0.1 | 0.5 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
| 0.0 | 0.5 | GO:0045577 | regulation of B cell differentiation(GO:0045577) |
| 0.1 | 0.4 | GO:1903348 | cellular response to lead ion(GO:0071284) positive regulation of bicellular tight junction assembly(GO:1903348) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 1.2 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 1.1 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 0.3 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 0.0 | 0.3 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.0 | 0.3 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.0 | 0.2 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.0 | 0.2 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.0 | 0.2 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.0 | 0.2 | GO:0036449 | microtubule minus-end(GO:0036449) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.8 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.4 | 1.1 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
| 0.1 | 1.1 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.1 | 0.9 | GO:0005381 | iron ion transmembrane transporter activity(GO:0005381) |
| 0.1 | 0.5 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.0 | 0.5 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.1 | 0.3 | GO:0004040 | amidase activity(GO:0004040) |
| 0.0 | 0.3 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.1 | 0.2 | GO:0033149 | FFAT motif binding(GO:0033149) |
| 0.1 | 0.2 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 0.7 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.6 | PID NECTIN PATHWAY | Nectin adhesion pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 1.1 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.2 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |