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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for NR3C1

Z-value: 0.90

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Transcription factors associated with NR3C1

Gene Symbol Gene ID Gene Info
NR3C1
ENSG00000113580.10 nuclear receptor subfamily 3 group C member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR3C1hg19_v2_chr5_-_142782862_1427828940.096.8e-01Click!

Activity profile of NR3C1 motif

Sorted Z-values of NR3C1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_47352477 2.01 ENST00000593412.1
PRED62
Uncharacterized protein
chr10_+_81466084 1.16 ENST00000342531.2
NUTM2B
NUT family member 2B
chr2_-_169769787 1.02 ENST00000451987.1
SPC25
SPC25, NDC80 kinetochore complex component
chr2_-_225266743 0.92 ENST00000409685.3
FAM124B
family with sequence similarity 124B
chr2_-_225266711 0.87 ENST00000389874.3
FAM124B
family with sequence similarity 124B
chr1_-_112032284 0.83 ENST00000414219.1
ADORA3
adenosine A3 receptor
chr20_-_62680984 0.79 ENST00000340356.7
SOX18
SRY (sex determining region Y)-box 18
chr5_-_172198190 0.77 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chrX_+_49969405 0.76 ENST00000376042.1
CCNB3
cyclin B3
chr19_+_13261216 0.74 ENST00000587885.1
ENST00000292433.3
IER2
immediate early response 2
chr8_-_8243968 0.73 ENST00000520004.1
SGK223
Tyrosine-protein kinase SgK223
chr12_-_95009837 0.72 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr11_-_105948040 0.69 ENST00000534815.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr14_-_106692191 0.65 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr19_+_35630344 0.65 ENST00000455515.2
FXYD1
FXYD domain containing ion transport regulator 1
chr19_+_46002868 0.65 ENST00000396735.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr11_+_7626950 0.63 ENST00000530181.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr6_-_146285455 0.63 ENST00000367505.2
SHPRH
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr12_-_42877726 0.62 ENST00000548696.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr16_-_88770019 0.61 ENST00000541206.2
RNF166
ring finger protein 166
chr15_-_72490114 0.61 ENST00000309731.7
GRAMD2
GRAM domain containing 2
chr16_+_76587314 0.58 ENST00000563764.1
RP11-58C22.1
Uncharacterized protein
chr17_-_1733114 0.58 ENST00000305513.7
SMYD4
SET and MYND domain containing 4
chr19_-_40440533 0.57 ENST00000221347.6
FCGBP
Fc fragment of IgG binding protein
chr12_+_53443963 0.57 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr2_-_75796837 0.57 ENST00000233712.1
EVA1A
eva-1 homolog A (C. elegans)
chr15_+_31658349 0.56 ENST00000558844.1
KLF13
Kruppel-like factor 13
chr19_+_35630926 0.55 ENST00000588081.1
ENST00000589121.1
FXYD1
FXYD domain containing ion transport regulator 1
chr11_-_105948129 0.55 ENST00000526793.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr2_-_170430277 0.55 ENST00000438035.1
ENST00000453929.2
FASTKD1
FAST kinase domains 1
chr6_-_109330702 0.54 ENST00000356644.7
SESN1
sestrin 1
chr19_+_35630628 0.54 ENST00000588715.1
ENST00000588607.1
FXYD1
FXYD domain containing ion transport regulator 1
chr15_+_55700741 0.53 ENST00000569691.1
C15orf65
chromosome 15 open reading frame 65
chr4_+_90033968 0.51 ENST00000317005.2
TIGD2
tigger transposable element derived 2
chr20_-_55100981 0.51 ENST00000243913.4
GCNT7
glucosaminyl (N-acetyl) transferase family member 7
chrX_-_62571187 0.49 ENST00000335144.3
SPIN4
spindlin family, member 4
chr22_-_17073700 0.49 ENST00000359963.3
CCT8L2
chaperonin containing TCP1, subunit 8 (theta)-like 2
chr6_+_123110302 0.48 ENST00000368440.4
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr20_-_45984401 0.47 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr15_+_49913175 0.46 ENST00000403028.3
DTWD1
DTW domain containing 1
chr5_-_149792295 0.46 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr20_-_45985172 0.46 ENST00000536340.1
ZMYND8
zinc finger, MYND-type containing 8
chr5_+_71616188 0.45 ENST00000380639.5
ENST00000543322.1
ENST00000503868.1
ENST00000510676.2
ENST00000536805.1
PTCD2
pentatricopeptide repeat domain 2
chr4_-_123843597 0.43 ENST00000510735.1
ENST00000304430.5
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr6_-_41909191 0.42 ENST00000512426.1
ENST00000372987.4
CCND3
cyclin D3
chr19_+_46003056 0.42 ENST00000401593.1
ENST00000396736.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr5_+_175740083 0.42 ENST00000332772.4
SIMC1
SUMO-interacting motifs containing 1
chr2_+_242750274 0.41 ENST00000405370.1
NEU4
sialidase 4
chr19_-_10341948 0.40 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
S1PR2
DNMT1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr4_-_135122903 0.40 ENST00000421491.3
ENST00000529122.2
PABPC4L
poly(A) binding protein, cytoplasmic 4-like
chr8_+_11351876 0.39 ENST00000529894.1
BLK
B lymphoid tyrosine kinase
chr9_-_34372830 0.39 ENST00000379142.3
KIAA1161
KIAA1161
chr6_+_123110465 0.39 ENST00000539041.1
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr3_-_75834670 0.38 ENST00000400845.3
ENST00000477374.1
ENST00000478296.1
ZNF717
zinc finger protein 717
chr19_+_8117881 0.38 ENST00000390669.3
CCL25
chemokine (C-C motif) ligand 25
chr19_+_8117636 0.38 ENST00000253451.4
ENST00000315626.4
CCL25
chemokine (C-C motif) ligand 25
chr22_+_21987005 0.37 ENST00000607942.1
ENST00000425975.1
ENST00000292779.3
CCDC116
coiled-coil domain containing 116
chr16_+_618837 0.37 ENST00000409439.2
PIGQ
phosphatidylinositol glycan anchor biosynthesis, class Q
chr17_-_72864739 0.36 ENST00000579893.1
ENST00000544854.1
FDXR
ferredoxin reductase
chr6_+_18387570 0.36 ENST00000259939.3
RNF144B
ring finger protein 144B
chr2_+_170440844 0.35 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr15_+_40643227 0.35 ENST00000448599.2
PHGR1
proline/histidine/glycine-rich 1
chr1_-_27693349 0.35 ENST00000374040.3
ENST00000357582.2
ENST00000493901.1
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr12_+_53443680 0.35 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr5_+_125935960 0.35 ENST00000297540.4
PHAX
phosphorylated adaptor for RNA export
chr14_+_88851874 0.35 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
SPATA7
spermatogenesis associated 7
chr19_+_11670245 0.34 ENST00000585493.1
ZNF627
zinc finger protein 627
chr15_-_55700216 0.34 ENST00000569205.1
CCPG1
cell cycle progression 1
chr22_+_22712087 0.33 ENST00000390294.2
IGLV1-47
immunoglobulin lambda variable 1-47
chr1_+_207262170 0.33 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr7_-_135412925 0.33 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr5_+_130506475 0.33 ENST00000379380.4
LYRM7
LYR motif containing 7
chr9_+_75263565 0.33 ENST00000396237.3
TMC1
transmembrane channel-like 1
chr2_+_66666432 0.33 ENST00000495021.2
MEIS1
Meis homeobox 1
chr17_+_76374714 0.32 ENST00000262764.6
ENST00000589689.1
ENST00000329897.7
ENST00000592043.1
ENST00000587356.1
PGS1
phosphatidylglycerophosphate synthase 1
chr4_-_186732048 0.32 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr1_+_207262578 0.32 ENST00000243611.5
ENST00000367076.3
C4BPB
complement component 4 binding protein, beta
chr16_-_71323271 0.32 ENST00000565850.1
ENST00000568910.1
ENST00000434935.2
ENST00000338099.5
CMTR2
cap methyltransferase 2
chr5_+_153570285 0.32 ENST00000425427.2
ENST00000297107.6
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr3_-_18480260 0.32 ENST00000454909.2
SATB1
SATB homeobox 1
chr15_+_69307028 0.32 ENST00000388866.3
ENST00000530406.2
NOX5
NADPH oxidase, EF-hand calcium binding domain 5
chr1_+_149230680 0.32 ENST00000443018.1
RP11-403I13.5
RP11-403I13.5
chrX_+_2984874 0.31 ENST00000359361.2
ARSF
arylsulfatase F
chr1_+_207262627 0.31 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr15_-_20193370 0.31 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr11_-_124190184 0.31 ENST00000357438.2
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr13_-_33924755 0.31 ENST00000439831.1
ENST00000567873.1
STARD13
StAR-related lipid transfer (START) domain containing 13
chr2_-_211168332 0.31 ENST00000341685.4
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr10_-_87551311 0.31 ENST00000536331.1
GRID1
glutamate receptor, ionotropic, delta 1
chr3_+_35721182 0.30 ENST00000413378.1
ENST00000417925.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr4_-_89744457 0.30 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr8_-_9008206 0.30 ENST00000310455.3
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr1_+_207262540 0.30 ENST00000452902.2
C4BPB
complement component 4 binding protein, beta
chr16_+_53088885 0.30 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr6_-_133079022 0.30 ENST00000525289.1
ENST00000326499.6
VNN2
vanin 2
chr13_-_36920872 0.30 ENST00000451493.1
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr19_-_7797045 0.30 ENST00000328853.5
CLEC4G
C-type lectin domain family 4, member G
chr19_-_36399149 0.29 ENST00000585901.2
ENST00000544690.2
ENST00000424586.3
ENST00000262629.4
ENST00000589517.1
TYROBP
TYRO protein tyrosine kinase binding protein
chr12_+_124997766 0.29 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr11_-_64570706 0.29 ENST00000294066.2
ENST00000377350.3
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chrX_-_102757802 0.29 ENST00000372633.1
RAB40A
RAB40A, member RAS oncogene family
chr16_-_34740829 0.28 ENST00000562591.1
RP11-80F22.15
RP11-80F22.15
chr17_+_5973793 0.28 ENST00000317744.5
WSCD1
WSC domain containing 1
chr18_-_72264805 0.28 ENST00000577806.1
LINC00909
long intergenic non-protein coding RNA 909
chr18_-_19994830 0.28 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr11_+_34664014 0.27 ENST00000527935.1
EHF
ets homologous factor
chr4_+_75310851 0.27 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr6_-_119031228 0.27 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr17_+_38333263 0.27 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr16_+_68119764 0.27 ENST00000570212.1
ENST00000562926.1
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr19_+_54058073 0.26 ENST00000505949.1
ENST00000513265.1
ZNF331
zinc finger protein 331
chr17_+_66245341 0.26 ENST00000577985.1
AMZ2
archaelysin family metallopeptidase 2
chr11_+_107461948 0.26 ENST00000265840.7
ENST00000443271.2
ELMOD1
ELMO/CED-12 domain containing 1
chr12_+_29542557 0.26 ENST00000550906.1
OVCH1-AS1
OVCH1 antisense RNA 1
chr2_-_165811756 0.26 ENST00000409662.1
SLC38A11
solute carrier family 38, member 11
chr2_-_158300556 0.26 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr4_+_147560042 0.26 ENST00000281321.3
POU4F2
POU class 4 homeobox 2
chr7_-_73153178 0.26 ENST00000437775.2
ENST00000222800.3
ABHD11
abhydrolase domain containing 11
chr4_+_164415594 0.26 ENST00000509657.1
ENST00000358572.5
TMA16
translation machinery associated 16 homolog (S. cerevisiae)
chr1_+_151512775 0.26 ENST00000368849.3
ENST00000392712.3
ENST00000353024.3
ENST00000368848.2
ENST00000538902.1
TUFT1
tuftelin 1
chr8_+_67624653 0.26 ENST00000521198.2
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr2_+_170440902 0.26 ENST00000448752.2
ENST00000418888.1
ENST00000414307.1
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr15_-_55700522 0.26 ENST00000564092.1
ENST00000310958.6
CCPG1
cell cycle progression 1
chr7_+_12726474 0.26 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
ARL4A
ADP-ribosylation factor-like 4A
chrX_+_152082969 0.25 ENST00000535861.1
ENST00000539731.1
ENST00000449285.2
ENST00000318504.7
ENST00000324823.6
ENST00000370268.4
ENST00000370270.2
ZNF185
zinc finger protein 185 (LIM domain)
chr14_+_88852059 0.25 ENST00000045347.7
SPATA7
spermatogenesis associated 7
chr2_-_152684977 0.25 ENST00000428992.2
ENST00000295087.8
ARL5A
ADP-ribosylation factor-like 5A
chr11_+_105948216 0.25 ENST00000278618.4
AASDHPPT
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr16_+_12058961 0.25 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr19_-_19843900 0.25 ENST00000344099.3
ZNF14
zinc finger protein 14
chr16_-_89785777 0.25 ENST00000561976.1
VPS9D1
VPS9 domain containing 1
chr14_-_23623577 0.25 ENST00000422941.2
ENST00000453702.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr3_+_142838091 0.25 ENST00000309575.3
CHST2
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr4_+_71587669 0.25 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr8_-_82754427 0.25 ENST00000353788.4
ENST00000520618.1
ENST00000518183.1
ENST00000396330.2
ENST00000519119.1
ENST00000345957.4
SNX16
sorting nexin 16
chr2_-_132559234 0.25 ENST00000303798.2
C2orf27B
chromosome 2 open reading frame 27B
chr1_-_85462762 0.25 ENST00000284027.5
MCOLN2
mucolipin 2
chr6_+_31638156 0.25 ENST00000409525.1
LY6G5B
lymphocyte antigen 6 complex, locus G5B
chr17_+_25799008 0.25 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chrX_-_19688475 0.25 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr15_-_51914996 0.25 ENST00000251076.5
DMXL2
Dmx-like 2
chr17_+_27573875 0.24 ENST00000225387.3
CRYBA1
crystallin, beta A1
chr15_+_78830023 0.24 ENST00000599596.1
AC027228.1
HCG2005369; Uncharacterized protein
chr15_-_81616446 0.24 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr19_-_2041159 0.24 ENST00000589441.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr5_+_158690089 0.24 ENST00000296786.6
UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr19_-_36545649 0.24 ENST00000292894.1
THAP8
THAP domain containing 8
chr17_-_39968406 0.24 ENST00000393928.1
LEPREL4
leprecan-like 4
chr19_-_51920835 0.24 ENST00000442846.3
ENST00000530476.1
SIGLEC10
sialic acid binding Ig-like lectin 10
chrX_+_48554986 0.23 ENST00000376687.3
ENST00000453214.2
SUV39H1
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr11_+_66059339 0.23 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chr4_+_74347400 0.23 ENST00000226355.3
AFM
afamin
chr4_+_166128735 0.23 ENST00000226725.6
KLHL2
kelch-like family member 2
chr10_+_695888 0.23 ENST00000441152.2
PRR26
proline rich 26
chr12_-_56848426 0.23 ENST00000257979.4
MIP
major intrinsic protein of lens fiber
chr11_+_101983176 0.23 ENST00000524575.1
YAP1
Yes-associated protein 1
chr12_-_58329819 0.23 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr14_-_68000442 0.23 ENST00000554278.1
TMEM229B
transmembrane protein 229B
chr10_-_102279586 0.23 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31B
SEC31 homolog B (S. cerevisiae)
chr20_-_23586513 0.23 ENST00000376971.3
CST9
cystatin 9 (testatin)
chr12_+_19358228 0.23 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr12_-_112450915 0.23 ENST00000437003.2
ENST00000552374.2
ENST00000550831.3
ENST00000354825.3
ENST00000549537.2
ENST00000355445.3
TMEM116
transmembrane protein 116
chr11_+_64018955 0.22 ENST00000279230.6
ENST00000540288.1
ENST00000325234.5
PLCB3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr11_+_47290914 0.22 ENST00000342922.4
MADD
MAP-kinase activating death domain
chr4_-_681114 0.22 ENST00000503156.1
MFSD7
major facilitator superfamily domain containing 7
chr15_-_55700457 0.22 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
CCPG1
cell cycle progression 1
chr2_+_235887329 0.22 ENST00000409212.1
ENST00000344528.4
ENST00000444916.1
SH3BP4
SH3-domain binding protein 4
chr19_-_15575369 0.22 ENST00000343625.7
RASAL3
RAS protein activator like 3
chr4_-_80247162 0.22 ENST00000286794.4
NAA11
N(alpha)-acetyltransferase 11, NatA catalytic subunit
chr16_-_4852915 0.22 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr12_+_52626898 0.22 ENST00000331817.5
KRT7
keratin 7
chr12_-_53901266 0.22 ENST00000609999.1
ENST00000267017.3
NPFF
neuropeptide FF-amide peptide precursor
chr6_+_32605195 0.22 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr1_+_84543821 0.22 ENST00000370688.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_+_101188718 0.21 ENST00000299222.9
ENST00000392977.3
ANO4
anoctamin 4
chr22_-_26875631 0.21 ENST00000402105.3
HPS4
Hermansky-Pudlak syndrome 4
chr10_-_5541525 0.21 ENST00000380332.3
CALML5
calmodulin-like 5
chr9_-_124989804 0.21 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr19_+_36157715 0.21 ENST00000379013.2
ENST00000222275.2
UPK1A
uroplakin 1A
chr22_+_39410287 0.21 ENST00000381568.4
APOBEC3D
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
chr1_+_162351503 0.21 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr8_+_128427857 0.21 ENST00000391675.1
POU5F1B
POU class 5 homeobox 1B
chr22_-_21580582 0.21 ENST00000424627.1
GGT2
gamma-glutamyltransferase 2
chr12_+_50497784 0.21 ENST00000548814.1
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr1_-_7913089 0.21 ENST00000361696.5
UTS2
urotensin 2
chr12_-_110486348 0.21 ENST00000547573.1
ENST00000546651.2
ENST00000551185.2
C12orf76
chromosome 12 open reading frame 76
chr7_-_16872932 0.20 ENST00000419572.2
ENST00000412973.1
AGR2
anterior gradient 2
chr1_-_40782938 0.20 ENST00000372736.3
ENST00000372748.3
COL9A2
collagen, type IX, alpha 2
chr4_+_87928140 0.20 ENST00000307808.6
AFF1
AF4/FMR2 family, member 1
chr15_+_49913201 0.20 ENST00000329873.5
ENST00000558653.1
ENST00000559164.1
ENST00000560632.1
ENST00000559405.1
ENST00000251250.6
DTWD1
DTW domain containing 1
chr22_+_25003568 0.20 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr16_+_23313591 0.20 ENST00000343070.2
SCNN1B
sodium channel, non-voltage-gated 1, beta subunit
chr19_-_36545128 0.20 ENST00000538849.1
THAP8
THAP domain containing 8
chr1_-_153066998 0.20 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr14_+_94385235 0.20 ENST00000557719.1
ENST00000267594.5
FAM181A
family with sequence similarity 181, member A
chr18_-_72265035 0.20 ENST00000585279.1
ENST00000580048.1
LINC00909
long intergenic non-protein coding RNA 909
chr1_-_241799232 0.20 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr10_+_120863587 0.20 ENST00000535029.1
ENST00000361432.2
ENST00000544016.1
FAM45A
family with sequence similarity 45, member A
chr14_-_61124977 0.20 ENST00000554986.1
SIX1
SIX homeobox 1
chr15_+_42694573 0.20 ENST00000397200.4
ENST00000569827.1
CAPN3
calpain 3, (p94)

Network of associatons between targets according to the STRING database.

First level regulatory network of NR3C1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.2 0.8 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.9 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.2 0.6 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.8 GO:0060214 stem cell fate commitment(GO:0048865) endocardium formation(GO:0060214)
0.1 0.4 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.1 1.2 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 0.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.3 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.1 0.3 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740) smooth muscle hyperplasia(GO:0014806)
0.1 0.3 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.1 0.5 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1 0.3 GO:0035922 pulmonary valve formation(GO:0003193) foramen ovale closure(GO:0035922)
0.1 0.3 GO:0006408 snRNA export from nucleus(GO:0006408)
0.1 0.4 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.3 GO:0070253 somatostatin secretion(GO:0070253)
0.1 0.3 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
0.1 0.4 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 0.2 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.7 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.5 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.2 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.4 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.2 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.1 0.2 GO:1900158 negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.2 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.4 GO:0097338 response to clozapine(GO:0097338)
0.1 0.6 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.5 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 0.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.2 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.1 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.2 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.2 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.2 GO:0007538 primary sex determination(GO:0007538)
0.0 0.2 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.0 0.1 GO:0048936 neurofilament bundle assembly(GO:0033693) peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.0 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.2 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.2 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.2 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.1 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.2 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:2000843 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 0.2 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.2 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.2 GO:0097039 CD40 signaling pathway(GO:0023035) protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.0 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.0 0.1 GO:1901907 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.2 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.3 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.2 GO:0061589 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.1 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0015755 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.1 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.3 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.6 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.0 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.1 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.3 GO:0060004 reflex(GO:0060004)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.6 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.2 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.0 0.0 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.0 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.2 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:0044597 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.0 GO:1904640 response to methionine(GO:1904640)
0.0 0.1 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.0 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.0 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.1 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0051967 serotonin receptor signaling pathway(GO:0007210) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.5 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.0 GO:0035811 negative regulation of urine volume(GO:0035811)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.4 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.1 0.2 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 1.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.2 GO:0071746 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.1 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0005713 recombination nodule(GO:0005713)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0097361 CIA complex(GO:0097361)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.1 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.1 GO:0019814 immunoglobulin complex(GO:0019814)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.0 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.0 GO:0031673 H zone(GO:0031673)
0.0 0.0 GO:0045160 myosin I complex(GO:0045160)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.2 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.8 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.4 GO:0015039 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 0.4 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.4 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.2 GO:0019862 IgA binding(GO:0019862)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.3 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.1 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.3 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.1 GO:0047025 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.3 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 1.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.3 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0052840 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 1.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.5 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 1.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 0.1 GO:0019239 deaminase activity(GO:0019239)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.0 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.0 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.6 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis