ISMARA results: UGGCACU

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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for UGGCACU

Z-value: 0.49

Activity profile of UGGCACU motif

Sorted Z-values of UGGCACU motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr3_+_39851094 Show fit	2.06	ENST00000302541.6	MYRIP Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin VIIA and Rab interacting protein
chr1_-_209979375 Show fit	1.75	ENST00000367021.3	IRF6 Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon regulatory factor 6
chr2_+_173600671 Show fit	1.62	ENST00000409036.1	RAPGEF4 Ensembl NCBI GeneCards UniProt NextProt Show fit	Rap guanine nucleotide exchange factor (GEF) 4
chr4_-_16900217 Show fit	1.62	ENST00000441778.2	LDB2 Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM domain binding 2
chr10_+_112631547 Show fit	1.58	ENST00000280154.7 ENST00000393104.2	PDCD4 Ensembl NCBI GeneCards UniProt NextProt Show fit	programmed cell death 4 (neoplastic transformation inhibitor)
chr9_+_79074068 Show fit	1.54	ENST00000444201.2 ENST00000376730.4	GCNT1 Ensembl NCBI GeneCards UniProt NextProt Show fit	glucosaminyl (N-acetyl) transferase 1, core 2
chr11_-_45687128 Show fit	1.50	ENST00000308064.2	CHST1 Ensembl NCBI GeneCards UniProt NextProt Show fit	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr5_-_100238956 Show fit	1.31	ENST00000231461.5	ST8SIA4 Ensembl NCBI GeneCards UniProt NextProt Show fit	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr12_+_27396901 Show fit	1.13	ENST00000541191.1 ENST00000389032.3	STK38L Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/threonine kinase 38 like
chr6_-_16761678 Show fit	1.10	ENST00000244769.4 ENST00000436367.1	ATXN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ataxin 1

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of UGGCACU

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.1	1.9	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.5	1.6	GO:0036446	myofibroblast differentiation(GO:0036446) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) regulation of myofibroblast differentiation(GO:1904760)
0.0	1.6	GO:0010669	epithelial structure maintenance(GO:0010669)
0.1	1.5	GO:0060352	cell adhesion molecule production(GO:0060352)
0.1	1.5	GO:0006012	galactose metabolic process(GO:0006012)
0.0	1.5	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.1	1.3	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	1.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.9	GO:0097503	sialylation(GO:0097503)

Showing 1 to 10 of 90 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	GO:0031045	dense core granule(GO:0031045)
0.0	2.1	GO:0031985	Golgi cisterna(GO:0031985)
0.2	1.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	1.0	GO:0030057	desmosome(GO:0030057)
0.2	0.6	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
0.0	0.6	GO:0071565	nBAF complex(GO:0071565)
0.0	0.6	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.5	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.5	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.5	GO:0005720	nuclear heterochromatin(GO:0005720)

Showing 1 to 10 of 19 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.5	GO:0051018	protein kinase A binding(GO:0051018)
0.1	1.6	GO:0030274	LIM domain binding(GO:0030274)
0.0	1.6	GO:0030552	cAMP binding(GO:0030552)
0.5	1.5	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2	1.5	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2	1.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2	1.1	GO:0034046	poly(G) binding(GO:0034046)
0.1	1.0	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	0.8	GO:0000298	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0	0.8	GO:0042605	peptide antigen binding(GO:0042605)

Showing 1 to 10 of 59 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Total log-likelihood	Term	Description
1.4	PID E2F PATHWAY	E2F transcription factor network
1.1	PID FOXO PATHWAY	FoxO family signaling
0.7	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.7	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.6	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.3	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha

Showing 1 to 8 of 8 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Total log-likelihood	Term	Description
2.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
2.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
1.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
1.4	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
1.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.7	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.6	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.6	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination

Showing 1 to 10 of 18 entries

Results for UGGCACU

Z-value: 0.49

Activity profile of UGGCACU motif

Sorted Z-values of UGGCACU motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of UGGCACU

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: