Motif ID: AAAGUGC

Z-value: 0.903


Mature miRNA associated with seed AAAGUGC:

NamemiRBase Accession
hsa-miR-106a MIMAT0000103
hsa-miR-106b MIMAT0000680
hsa-miR-17 MIMAT0000070
hsa-miR-20a MIMAT0000075
hsa-miR-20b MIMAT0001413
hsa-miR-519d MIMAT0002853
hsa-miR-93 MIMAT0000093



Activity profile for motif AAAGUGC.

activity profile for motif AAAGUGC


Sorted Z-values histogram for motif AAAGUGC

Sorted Z-values for motif AAAGUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAAGUGC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_4152182 2.303 NM_152629
GLIS3
GLIS family zinc finger 3
chr9_-_4300028 2.267 NM_001042413
GLIS3
GLIS family zinc finger 3
chr13_+_36050885 2.118 NM_001204197
NBEA
neurobeachin
chr13_+_35516390 1.792 NM_015678
NBEA
neurobeachin
chr1_+_118148506 1.698 NM_017709
FAM46C
family with sequence similarity 46, member C
chr6_-_90121966 1.329 NM_021244
RRAGD
Ras-related GTP binding D
chr9_-_124984018 1.294 NM_001242335
LHX6
LIM homeobox 6
chr11_+_100862719 1.226 NM_032021
TMEM133
transmembrane protein 133
chr2_-_19558371 1.166 NM_145260
OSR1
odd-skipped related 1 (Drosophila)
chr9_-_124990949 1.163 NM_014368
NM_199160
LHX6

LIM homeobox 6

chrX_+_16964730 1.159 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr4_+_72052354 1.147 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr9_-_124990706 1.139 NM_001242333
LHX6
LIM homeobox 6
chrX_+_9431314 1.093 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr3_-_66550844 1.075 NM_015541
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr3_-_145968958 1.068 NM_001128306
NM_001177304
NM_020353
PLSCR4


phospholipid scramblase 4


chr2_-_190445521 1.036 NM_014585
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr1_+_244214552 1.011 NM_205768
ZNF238
zinc finger protein 238
chr2_-_222436996 1.003 NM_004438
EPHA4
EPH receptor A4
chr1_+_183605207 0.979 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr9_+_74729510 0.972 NM_001242507
GDA
guanine deaminase
chr2_+_85980600 0.971 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr16_+_57406398 0.966 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr5_+_149151502 0.963 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr11_+_109964086 0.955 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr6_-_167275657 0.925 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr13_-_29292961 0.923 NM_001135919
NM_181785
SLC46A3

solute carrier family 46, member 3

chr1_+_244216506 0.914 NM_006352
ZNF238
zinc finger protein 238
chr2_-_157189040 0.905 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr5_+_149109814 0.902 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr6_-_167040700 0.890 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chrX_+_9432980 0.884 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr5_-_134914968 0.882 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr1_-_75139421 0.872 NM_001002912
C1orf173
chromosome 1 open reading frame 173
chr21_-_43373938 0.867 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr6_-_46138584 0.843 NM_021572
ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr5_-_9546157 0.800 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr11_-_108464344 0.795 NM_015065
EXPH5
exophilin 5
chr9_-_124989755 0.788 NM_001242334
LHX6
LIM homeobox 6
chr12_+_72233486 0.773 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15


chr4_+_72204769 0.773 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr2_+_97481977 0.752 NM_017623
NM_199078
CNNM3

cyclin M3

chr7_+_29603388 0.702 NM_175887
PRR15
proline rich 15
chr15_-_93616891 0.698 NM_001166288
NM_001166289
RGMA

RGM domain family, member A

chr6_+_33422319 0.677 NM_152735
ZBTB9
zinc finger and BTB domain containing 9
chr11_+_45868668 0.671 NM_001127457
CRY2
cryptochrome 2 (photolyase-like)
chr9_+_4679557 0.667 NM_017913
CDC37L1
cell division cycle 37 homolog (S. cerevisiae)-like 1
chr12_-_89918531 0.665 NM_003774
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr1_+_3569098 0.663 NM_001204184
NM_001204185
NM_001204186
NM_001204187
NM_001204188
NM_005427
TP73





tumor protein p73





chr11_+_45868956 0.663 NM_021117
CRY2
cryptochrome 2 (photolyase-like)
chr2_-_25194772 0.649 NM_001198559
NM_016544
DNAJC27

DnaJ (Hsp40) homolog, subfamily C, member 27

chr21_-_43346780 0.649 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr15_-_93632161 0.646 NM_020211
RGMA
RGM domain family, member A
chr18_+_55888750 0.642 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr6_+_107811272 0.641 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr9_-_130742803 0.640 NM_001035254
FAM102A
family with sequence similarity 102, member A
chr5_-_693413 0.631 NM_007030
TPPP
tubulin polymerization promoting protein
chr15_-_93617091 0.629 NM_001166283
RGMA
RGM domain family, member A
chr7_-_105319608 0.627 NM_138495
ATXN7L1
ataxin 7-like 1
chr9_+_74764266 0.626 NM_001242505
NM_001242506
NM_004293
GDA


guanine deaminase


chr6_+_148663728 0.624 NM_015278
SASH1
SAM and SH3 domain containing 1
chr15_-_93616358 0.623 NM_001166286
RGMA
RGM domain family, member A
chr3_-_13008959 0.622 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr15_+_67000929 0.618 NM_001142861
SMAD6
SMAD family member 6
chr1_+_3607232 0.618 NM_001126240
NM_001126241
NM_001126242
NM_001204189
NM_001204190
NM_001204191
TP73





tumor protein p73





chr3_+_101443436 0.611 NM_024548
CEP97
centrosomal protein 97kDa
chr15_-_93631751 0.611 NM_001166287
RGMA
RGM domain family, member A
chr3_-_46037299 0.610 NM_024513
FYCO1
FYVE and coiled-coil domain containing 1
chr5_+_140254930 0.600 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr1_+_145438437 0.596 NM_006472
TXNIP
thioredoxin interacting protein
chr12_-_26277807 0.589 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr5_+_140213968 0.588 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr1_+_3614609 0.585 NM_001204192
TP73
tumor protein p73
chr15_+_75287829 0.581 NM_001178111
NM_001178112
NM_138967
SCAMP5


secretory carrier membrane protein 5


chr17_+_29718641 0.581 NM_032932
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr3_-_23958500 0.580 NM_020345
NKIRAS1
NFKB inhibitor interacting Ras-like 1
chr21_-_43430448 0.579 NM_001098402
NM_001098403
NM_020727
ZNF295


zinc finger protein 295


chr17_+_8924822 0.576 NM_004822
NTN1
netrin 1
chr2_-_219432955 0.574 NM_020935
USP37
ubiquitin specific peptidase 37
chr16_+_53468344 0.572 NM_005611
RBL2
retinoblastoma-like 2 (p130)
chr5_+_140220811 0.569 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr16_-_67450149 0.559 NM_013304
ZDHHC1
zinc finger, DHHC-type containing 1
chr10_-_46168156 0.558 NM_001128324
NM_174890
ZFAND4

zinc finger, AN1-type domain 4

chr5_+_140186658 0.551 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr2_+_10184371 0.549 NM_001177718
KLF11
Kruppel-like factor 11
chr2_-_218808705 0.548 NM_022648
TNS1
tensin 1
chr4_-_125633716 0.540 NM_001167882
NM_020337
ANKRD50

ankyrin repeat domain 50

chr17_-_47439326 0.540 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr10_-_94050799 0.540 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr2_+_10183630 0.535 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr12_+_121647659 0.533 NM_002560
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr20_+_60718473 0.532 NM_198935
SS18L1
synovial sarcoma translocation gene on chromosome 18-like 1
chr10_-_94003002 0.525 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr5_+_72921980 0.521 NM_001080479
NM_001177693
RGNEF

190 kDa guanine nucleotide exchange factor

chr15_+_89631380 0.513 NM_007011
NM_152924
ABHD2

abhydrolase domain containing 2

chr6_+_16129285 0.506 NM_013262
MYLIP
myosin regulatory light chain interacting protein
chr5_+_98104998 0.505 NM_001012761
RGMB
RGM domain family, member B
chr14_+_74111577 0.503 NM_001201366
NM_031427
DNAL1

dynein, axonemal, light chain 1

chr1_-_236445294 0.501 NM_019891
ERO1LB
ERO1-like beta (S. cerevisiae)
chr5_+_140247767 0.499 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr5_-_114880536 0.496 NM_020177
FEM1C
fem-1 homolog c (C. elegans)
chr12_-_50297575 0.495 NM_012306
FAIM2
Fas apoptotic inhibitory molecule 2
chr14_+_58765209 0.492 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr16_-_87417309 0.485 NM_024735
FBXO31
F-box protein 31
chr18_+_55714457 0.483 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr5_+_140207562 0.472 NM_018909
NM_031848
NM_031849
PCDHA6


protocadherin alpha 6


chr17_-_38083762 0.470 NM_139280
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr1_+_67218104 0.467 NM_152665
TCTEX1D1
Tctex1 domain containing 1
chr22_+_30279064 0.467 NM_021090
NM_153050
NM_153051
MTMR3


myotubularin related protein 3


chr16_+_69599868 0.460 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr18_+_55711388 0.458 NM_001144967
NM_001243960
NM_015277
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like


chrX_-_24045302 0.455 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr3_-_13114547 0.452 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr4_-_53525316 0.446 NM_022832
USP46
ubiquitin specific peptidase 46
chr11_-_108093328 0.444 NM_002519
NPAT
nuclear protein, ataxia-telangiectasia locus
chr21_-_36421586 0.442 NM_001754
RUNX1
runt-related transcription factor 1
chr19_+_38397841 0.441 NM_015073
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr1_-_157015161 0.438 NM_014784
NM_198236
ARHGEF11

Rho guanine nucleotide exchange factor (GEF) 11

chr5_-_122759003 0.438 NM_001166226
NM_153223
CEP120

centrosomal protein 120kDa

chr14_-_89020888 0.438 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr3_+_140950671 0.435 NM_001037172
NM_152282
ACPL2

acid phosphatase-like 2

chr6_-_137113624 0.434 NM_005923
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr17_+_41132581 0.431 NM_173079
RUNDC1
RUN domain containing 1
chr18_+_9137560 0.431 NM_001204056
ANKRD12
ankyrin repeat domain 12
chr10_+_120789227 0.430 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr14_-_38064440 0.422 NM_004496
FOXA1
forkhead box A1
chr18_+_67956136 0.422 NM_004232
SOCS6
suppressor of cytokine signaling 6
chr17_+_4981721 0.422 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chr15_+_86220267 0.420 NM_144767
AKAP13
A kinase (PRKA) anchor protein 13
chr9_-_112260529 0.419 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr4_-_85887543 0.419 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr2_-_197036301 0.418 NM_004226
STK17B
serine/threonine kinase 17b
chr2_-_240322620 0.417 NM_006037
HDAC4
histone deacetylase 4
chr8_+_107460151 0.416 NM_001198532
OXR1
oxidation resistance 1
chr9_-_112213663 0.416 NM_001145369
NM_001145370
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr5_+_142150291 0.414 NM_001135608
NM_015071
ARHGAP26

Rho GTPase activating protein 26

chrX_-_53310748 0.414 NM_001243197
NM_015075
IQSEC2

IQ motif and Sec7 domain 2

chr16_+_14164879 0.414 NM_014048
MKL2
MKL/myocardin-like 2
chr11_-_113746205 0.408 NM_020886
USP28
ubiquitin specific peptidase 28
chr11_-_6494985 0.407 NM_001248007
NM_006458
NM_033278
TRIM3


tripartite motif containing 3


chr12_+_131438451 0.405 NM_198827
GPR133
G protein-coupled receptor 133
chr4_+_7045142 0.405 NM_152293
TADA2B
transcriptional adaptor 2B
chr15_+_85923739 0.404 NM_006738
NM_007200
AKAP13

A kinase (PRKA) anchor protein 13

chr10_-_61469322 0.404 NM_194298
LOC100129721
SLC16A9
uncharacterized LOC100129721
solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr14_-_92506284 0.402 NM_004239
TRIP11
thyroid hormone receptor interactor 11
chr8_+_107669895 0.399 NM_181354
OXR1
oxidation resistance 1
chr20_-_47444404 0.399 NM_020820
PREX1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr16_+_1664640 0.398 NM_020825
CRAMP1L
Crm, cramped-like (Drosophila)
chr3_+_20081523 0.395 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr17_+_57408907 0.394 NM_001005404
YPEL2
yippee-like 2 (Drosophila)
chrY_+_2803409 0.388 NM_001145275
NM_003411
ZFY

zinc finger protein, Y-linked

chr14_+_60712469 0.387 NM_177952
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr5_+_140165875 0.385 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr18_-_30050394 0.383 NM_001242409
NM_022751
FAM59A

family with sequence similarity 59, member A

chr18_-_72921280 0.382 NM_175907
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr4_-_89744154 0.381 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr8_+_86099909 0.380 NM_001083589
E2F5
E2F transcription factor 5, p130-binding
chr2_+_179345194 0.380 NM_019091
PLEKHA3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr18_+_10454620 0.376 NM_153000
APCDD1
adenomatosis polyposis coli down-regulated 1
chr18_+_55862577 0.375 NM_001144970
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chrY_+_2803111 0.374 NM_001145276
ZFY
zinc finger protein, Y-linked
chr6_-_47277646 0.372 NM_014452
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr19_+_50380681 0.369 NM_001168222
NM_024682
TBC1D17

TBC1 domain family, member 17

chr22_-_22089975 0.368 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr8_+_107738239 0.365 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr12_-_65153189 0.364 NM_002076
GNS
glucosamine (N-acetyl)-6-sulfatase
chr4_-_53522756 0.361 NM_001134223
USP46
ubiquitin specific peptidase 46
chr9_-_112191105 0.360 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr18_+_55816546 0.359 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chrX_+_119384490 0.358 NM_006777
NM_001184742
ZBTB33

zinc finger and BTB domain containing 33

chr8_+_86089618 0.357 NM_001083588
NM_001951
E2F5

E2F transcription factor 5, p130-binding

chr1_-_160232286 0.354 NM_015726
DCAF8
DDB1 and CUL4 associated factor 8
chr6_-_79787939 0.351 NM_017934
PHIP
pleckstrin homology domain interacting protein
chr15_-_52483564 0.349 NM_016194
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr7_+_30174343 0.347 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr11_-_73309090 0.347 NM_015159
FAM168A
family with sequence similarity 168, member A
chr19_+_18208596 0.337 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr21_+_45432202 0.337 NM_003274
TRAPPC10
trafficking protein particle complex 10
chr11_+_48002063 0.336 NM_001098503
NM_002843
PTPRJ

protein tyrosine phosphatase, receptor type, J

chr12_+_56414688 0.335 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr2_-_96931744 0.334 NM_001193304
NM_017849
TMEM127

transmembrane protein 127

chr10_+_93558139 0.334 NM_025235
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr1_-_151798552 0.332 NM_001001523
RORC
RAR-related orphan receptor C
chrX_-_10851808 0.330 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr1_+_33722158 0.330 NM_152493
ZNF362
zinc finger protein 362
chrX_-_108976509 0.330 NM_004458
NM_022977
ACSL4

acyl-CoA synthetase long-chain family member 4

chr12_+_56473808 0.326 NM_001982
NM_001005915
ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

chr8_-_82754427 0.322 NM_022133
NM_152836
NM_152837
SNX16


sorting nexin 16


chr7_-_2354050 0.321 NM_013321
SNX8
sorting nexin 8
chr12_-_89920038 0.320 NM_001199781
NM_001199782
NM_172240
POC1B-GALNT4

POC1B
POC1B-GALNT4 readthrough

POC1 centriolar protein homolog B (Chlamydomonas)
chr15_+_44719578 0.319 NM_016396
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr21_+_44394634 0.319 NM_004571
PKNOX1
PBX/knotted 1 homeobox 1
chr12_-_117628112 0.315 NM_015002
NM_033624
FBXO21

F-box protein 21

chr5_-_133968463 0.310 NM_001033503
NM_016103
SAR1B

SAR1 homolog B (S. cerevisiae)

chr7_+_130794854 0.307 NM_001145354
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr17_-_40897025 0.306 NM_001991
EZH1
enhancer of zeste homolog 1 (Drosophila)
chr11_-_130184459 0.303 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr20_+_51801821 0.302 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr15_-_52472075 0.301 NM_006578
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr16_-_1429612 0.298 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.88 5.07e-07 GO:0006464 protein modification process
1.82 2.05e-06 GO:0043412 macromolecule modification
3.13 4.21e-06 GO:0051056 regulation of small GTPase mediated signal transduction
1.96 6.67e-06 GO:0009966 regulation of signal transduction
1.46 1.32e-05 GO:0044260 cellular macromolecule metabolic process
1.85 1.95e-05 GO:0023051 regulation of signaling
2.06 1.21e-04 GO:0006793 phosphorus metabolic process
2.06 1.21e-04 GO:0006796 phosphate metabolic process
1.60 2.11e-04 GO:0044267 cellular protein metabolic process
2.06 8.96e-04 GO:0006351 transcription, DNA-dependent
2.30 9.08e-04 GO:0045893 positive regulation of transcription, DNA-dependent
2.41 1.01e-03 GO:0045892 negative regulation of transcription, DNA-dependent
3.18 1.06e-03 GO:0046578 regulation of Ras protein signal transduction
1.36 1.12e-03 GO:0043170 macromolecule metabolic process
1.55 1.17e-03 GO:0010468 regulation of gene expression
2.22 1.22e-03 GO:0010628 positive regulation of gene expression
2.36 1.66e-03 GO:0051253 negative regulation of RNA metabolic process
2.57 2.00e-03 GO:0007243 intracellular protein kinase cascade
2.57 2.00e-03 GO:0023014 signal transduction via phosphorylation event
1.43 2.37e-03 GO:0031323 regulation of cellular metabolic process
1.27 2.45e-03 GO:0050794 regulation of cellular process
2.26 2.67e-03 GO:0010629 negative regulation of gene expression
1.43 2.82e-03 GO:0080090 regulation of primary metabolic process
1.64 2.85e-03 GO:0048583 regulation of response to stimulus
2.65 3.30e-03 GO:0016568 chromatin modification
1.92 4.84e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.14 5.57e-03 GO:0051254 positive regulation of RNA metabolic process
1.39 6.62e-03 GO:0019222 regulation of metabolic process
2.15 6.81e-03 GO:0007167 enzyme linked receptor protein signaling pathway
2.06 6.99e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.43 7.24e-03 GO:0060255 regulation of macromolecule metabolic process
2.71 7.61e-03 GO:0006511 ubiquitin-dependent protein catabolic process
1.56 8.78e-03 GO:0006355 regulation of transcription, DNA-dependent
1.54 8.80e-03 GO:0051252 regulation of RNA metabolic process
2.65 1.09e-02 GO:0019941 modification-dependent protein catabolic process
1.52 1.10e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.64 1.23e-02 GO:0043632 modification-dependent macromolecule catabolic process
2.12 1.48e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.72 1.55e-02 GO:0035556 intracellular signal transduction
2.45 1.58e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.59 1.75e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.86 1.86e-02 GO:0032774 RNA biosynthetic process
1.49 2.10e-02 GO:0010556 regulation of macromolecule biosynthetic process
2.29 2.13e-02 GO:0006325 chromatin organization
2.11 2.22e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.28 2.34e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.45 2.36e-02 GO:0048731 system development
1.96 2.37e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.98 2.44e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.54 2.45e-02 GO:0044257 cellular protein catabolic process
1.23 2.55e-02 GO:0050789 regulation of biological process
1.49 2.70e-02 GO:0048522 positive regulation of cellular process
1.46 2.70e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.09 2.94e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.91 2.99e-02 GO:0016310 phosphorylation
1.91 2.99e-02 GO:0031328 positive regulation of cellular biosynthetic process
2.03 4.11e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
2.46 4.21e-02 GO:0006917 induction of apoptosis
2.45 4.44e-02 GO:0012502 induction of programmed cell death
1.88 4.60e-02 GO:0009891 positive regulation of biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.46 9.25e-10 GO:0005634 nucleus
1.19 7.11e-08 GO:0005622 intracellular
1.19 4.13e-07 GO:0044424 intracellular part
1.76 7.10e-06 GO:0031981 nuclear lumen
1.90 1.27e-05 GO:0005654 nucleoplasm
1.21 1.75e-05 GO:0043229 intracellular organelle
1.21 2.24e-05 GO:0043226 organelle
1.22 5.05e-05 GO:0043231 intracellular membrane-bounded organelle
1.22 5.77e-05 GO:0043227 membrane-bounded organelle
1.60 2.34e-04 GO:0044428 nuclear part
2.04 1.46e-03 GO:0044451 nucleoplasm part
1.49 6.61e-03 GO:0070013 intracellular organelle lumen
1.46 1.48e-02 GO:0043233 organelle lumen
1.45 1.74e-02 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.76 6.91e-07 GO:0008270 zinc ion binding
1.49 1.48e-06 GO:0046872 metal ion binding
2.34 2.10e-06 GO:0019899 enzyme binding
1.47 3.52e-06 GO:0043169 cation binding
2.12 4.15e-06 GO:0001071 nucleic acid binding transcription factor activity
2.12 4.15e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.47 4.24e-06 GO:0043167 ion binding
3.23 6.02e-06 GO:0005083 small GTPase regulator activity
2.63 2.22e-05 GO:0030695 GTPase regulator activity
2.56 4.43e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.59 9.70e-05 GO:0003677 DNA binding
1.97 1.21e-04 GO:0030528 transcription regulator activity
1.58 1.91e-04 GO:0046914 transition metal ion binding
11.31 4.54e-04 GO:0004709 MAP kinase kinase kinase activity
1.24 1.15e-03 GO:0005515 protein binding
2.66 2.15e-03 GO:0016564 transcription repressor activity
1.13 2.37e-03 GO:0005488 binding
3.35 2.61e-03 GO:0000287 magnesium ion binding
1.41 2.68e-03 GO:0003676 nucleic acid binding
1.83 6.37e-03 GO:0030234 enzyme regulator activity
2.27 7.09e-03 GO:0004674 protein serine/threonine kinase activity
5.12 7.36e-03 GO:0008276 protein methyltransferase activity
6.47 8.42e-03 GO:0018024 histone-lysine N-methyltransferase activity
6.30 1.03e-02 GO:0016278 lysine N-methyltransferase activity
6.30 1.03e-02 GO:0016279 protein-lysine N-methyltransferase activity
17.55 1.20e-02 GO:0031624 ubiquitin conjugating enzyme binding
4.28 1.65e-02 GO:0031625 ubiquitin protein ligase binding
3.09 2.22e-02 GO:0005085 guanyl-nucleotide exchange factor activity
2.59 2.43e-02 GO:0005096 GTPase activator activity
1.91 2.60e-02 GO:0043565 sequence-specific DNA binding
1.87 2.90e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.96 2.99e-02 GO:0004672 protein kinase activity
3.69 3.35e-02 GO:0005057 receptor signaling protein activity
6.14 3.84e-02 GO:0004843 ubiquitin-specific protease activity
5.23 4.18e-02 GO:0042054 histone methyltransferase activity