Motif ID: AAGUGCU

Z-value: 0.963


Mature miRNA associated with seed AAGUGCU:

NamemiRBase Accession
hsa-miR-302a MIMAT0000684
hsa-miR-302b MIMAT0000715
hsa-miR-302c MIMAT0000717
hsa-miR-302d MIMAT0000718
hsa-miR-302e MIMAT0005931
hsa-miR-372 MIMAT0000724
hsa-miR-373 MIMAT0000726
hsa-miR-520a-3p MIMAT0002834
hsa-miR-520b MIMAT0002843
hsa-miR-520c-3p MIMAT0002846
hsa-miR-520d-3p MIMAT0002856
hsa-miR-520e MIMAT0002825



Activity profile for motif AAGUGCU.

activity profile for motif AAGUGCU


Sorted Z-values histogram for motif AAGUGCU

Sorted Z-values for motif AAGUGCU



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGUGCU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_52580805 5.620 NM_001080430
TOX3
TOX high mobility group box family member 3
chr16_-_52581713 5.390 NM_001146188
TOX3
TOX high mobility group box family member 3
chr1_-_75139421 3.771 NM_001002912
C1orf173
chromosome 1 open reading frame 173
chr1_+_183605207 3.449 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr9_-_4300028 3.217 NM_001042413
GLIS3
GLIS family zinc finger 3
chr6_-_90121966 3.140 NM_021244
RRAGD
Ras-related GTP binding D
chr9_-_4152182 3.112 NM_152629
GLIS3
GLIS family zinc finger 3
chr3_-_145968958 2.792 NM_001128306
NM_001177304
NM_020353
PLSCR4


phospholipid scramblase 4


chr2_+_121103670 2.729 NM_002193
INHBB
inhibin, beta B
chr10_+_115803805 2.616 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr9_-_124984018 2.551 NM_001242335
LHX6
LIM homeobox 6
chr9_-_124990949 2.425 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr1_+_61547625 2.403 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr5_-_134914968 2.378 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr9_-_124990706 2.308 NM_001242333
LHX6
LIM homeobox 6
chr1_+_61542928 2.255 NM_001145511
NFIA
nuclear factor I/A
chr15_-_93632161 2.087 NM_020211
RGMA
RGM domain family, member A
chr15_-_93616891 2.044 NM_001166288
NM_001166289
RGMA

RGM domain family, member A

chr9_+_74729510 2.038 NM_001242507
GDA
guanine deaminase
chr15_-_93617091 1.925 NM_001166283
RGMA
RGM domain family, member A
chr1_+_244214552 1.915 NM_205768
ZNF238
zinc finger protein 238
chr1_+_61547388 1.884 NM_001145512
NFIA
nuclear factor I/A
chr15_-_93616358 1.849 NM_001166286
RGMA
RGM domain family, member A
chr15_-_93631751 1.806 NM_001166287
RGMA
RGM domain family, member A
chr1_+_3607232 1.746 NM_001126240
NM_001126241
NM_001126242
NM_001204189
NM_001204190
NM_001204191
TP73





tumor protein p73





chr1_+_3569098 1.726 NM_001204184
NM_001204185
NM_001204186
NM_001204187
NM_001204188
NM_005427
TP73





tumor protein p73





chr20_+_51588945 1.706 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr2_-_190445521 1.706 NM_014585
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr1_+_244216506 1.697 NM_006352
ZNF238
zinc finger protein 238
chr1_+_118148506 1.670 NM_017709
FAM46C
family with sequence similarity 46, member C
chr9_-_124989755 1.667 NM_001242334
LHX6
LIM homeobox 6
chr1_+_3614609 1.618 NM_001204192
TP73
tumor protein p73
chr3_-_13008959 1.616 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr2_+_97481977 1.572 NM_017623
NM_199078
CNNM3

cyclin M3

chr20_+_51801821 1.572 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr22_+_29279573 1.560 NM_001206998
ZNRF3
zinc and ring finger 3
chr17_+_4981721 1.544 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chr21_-_43373938 1.522 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr5_+_149109814 1.509 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr6_+_33422319 1.473 NM_152735
ZBTB9
zinc finger and BTB domain containing 9
chr5_+_149151502 1.463 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr11_-_108464344 1.440 NM_015065
EXPH5
exophilin 5
chr6_+_18155535 1.400 NM_153042
KDM1B
lysine (K)-specific demethylase 1B
chr13_-_29292961 1.389 NM_001135919
NM_181785
SLC46A3

solute carrier family 46, member 3

chr2_+_172378856 1.384 NM_001127383
NM_024843
CYBRD1

cytochrome b reductase 1

chr14_-_89020888 1.351 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr9_+_74764266 1.339 NM_001242505
NM_001242506
NM_004293
GDA


guanine deaminase


chr2_-_157189040 1.328 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr1_-_226128872 1.313 NM_001172425
NM_003240
LEFTY2

left-right determination factor 2

chr6_-_167040700 1.271 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_-_46598250 1.268 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr10_+_115511212 1.267 NM_001193434
NM_001193435
NM_024889
C10orf81


chromosome 10 open reading frame 81


chr6_-_167275657 1.264 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr15_-_61521478 1.237 NM_134261
RORA
RAR-related orphan receptor A
chr9_-_130742803 1.198 NM_001035254
FAM102A
family with sequence similarity 102, member A
chr10_-_61469322 1.198 NM_194298
LOC100129721
SLC16A9
uncharacterized LOC100129721
solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr7_+_94536926 1.155 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory subunit 9A

chr12_-_56652118 1.142 NM_173595
ANKRD52
ankyrin repeat domain 52
chr1_-_236445294 1.130 NM_019891
ERO1LB
ERO1-like beta (S. cerevisiae)
chr14_+_73525187 1.121 NM_021239
RBM25
RNA binding motif protein 25
chr17_+_53342320 1.107 NM_002126
HLF
hepatic leukemia factor
chr15_-_60884615 1.100 NM_134262
RORA
RAR-related orphan receptor A
chr20_+_60718473 1.093 NM_198935
SS18L1
synovial sarcoma translocation gene on chromosome 18-like 1
chr2_-_213403280 1.063 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr1_+_107599266 1.026 NM_018137
PRMT6
protein arginine methyltransferase 6
chr7_+_94539209 1.017 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr5_+_98104998 1.016 NM_001012761
RGMB
RGM domain family, member B
chr6_+_126111782 1.012 NM_001122842
NM_001199621
NM_181782
NCOA7


nuclear receptor coactivator 7


chr8_-_17555158 1.009 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr6_-_80247103 0.999 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr17_+_36861857 0.997 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr11_-_130184459 0.981 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr15_-_77712436 0.969 NM_024776
PEAK1
NKF3 kinase family member
chr15_-_60919642 0.967 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr8_-_17580024 0.964 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr5_+_49962771 0.959 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr7_-_105319608 0.957 NM_138495
ATXN7L1
ataxin 7-like 1
chr3_-_187454247 0.957 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr14_-_92506284 0.952 NM_004239
TRIP11
thyroid hormone receptor interactor 11
chr2_+_10861740 0.937 NM_001039362
NM_144583
ATP6V1C2

ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2

chr3_-_187452669 0.936 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr22_+_29313376 0.932 NM_032173
ZNRF3
zinc and ring finger 3
chr11_-_132812870 0.927 NM_002545
OPCML
opioid binding protein/cell adhesion molecule-like
chr11_+_120894756 0.921 NM_001130047
NM_152715
TBCEL

tubulin folding cofactor E-like

chr17_+_57408907 0.919 NM_001005404
YPEL2
yippee-like 2 (Drosophila)
chr3_-_13114547 0.919 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr2_-_25194772 0.909 NM_001198559
NM_016544
DNAJC27

DnaJ (Hsp40) homolog, subfamily C, member 27

chr11_+_61520000 0.900 NM_001127392
C11orf9
chromosome 11 open reading frame 9
chr8_-_17579729 0.884 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr8_+_17354562 0.876 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr8_-_17658385 0.865 NM_001001924
NM_001001925
MTUS1

microtubule associated tumor suppressor 1

chr21_-_36421586 0.852 NM_001754
RUNX1
runt-related transcription factor 1
chrX_-_25034064 0.852 NM_139058
ARX
aristaless related homeobox
chr6_+_126240369 0.833 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr11_+_73019662 0.832 NM_014786
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr12_+_122459791 0.818 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chrX_-_20284708 0.818 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr11_+_109964086 0.815 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr1_+_145438437 0.811 NM_006472
TXNIP
thioredoxin interacting protein
chr11_-_62475060 0.808 NM_001122955
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr1_+_33722158 0.790 NM_152493
ZNF362
zinc finger protein 362
chr9_-_130712866 0.787 NM_203305
FAM102A
family with sequence similarity 102, member A
chr20_-_47894591 0.787 NM_021035
ZNFX1
zinc finger, NFX1-type containing 1
chr1_+_110036657 0.784 NM_001134402
NM_001134400
NM_001134403
NM_001134404
NM_182580
CYB561D1




cytochrome b-561 domain containing 1




chr10_-_94050799 0.782 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr4_+_30721865 0.775 NM_032456
NM_001173523
NM_002589
NM_032457
PCDH7



protocadherin 7



chr10_+_65281108 0.774 NM_001001330
REEP3
receptor accessory protein 3
chr19_+_38397841 0.772 NM_015073
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr2_-_172750724 0.764 NM_003705
SLC25A12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr17_-_38083762 0.760 NM_139280
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr5_+_74807580 0.757 NM_016218
POLK
polymerase (DNA directed) kappa
chr4_-_170924911 0.751 NM_001009554
MFAP3L
microfibrillar-associated protein 3-like
chr17_-_47439326 0.749 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr3_-_46037299 0.747 NM_024513
FYCO1
FYVE and coiled-coil domain containing 1
chr8_+_28351694 0.746 NM_017412
NM_145866
FZD3

frizzled family receptor 3

chr3_-_187463474 0.746 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr12_+_121647659 0.743 NM_002560
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr4_-_53525316 0.740 NM_022832
USP46
ubiquitin specific peptidase 46
chr10_+_92980322 0.735 NM_032373
PCGF5
polycomb group ring finger 5
chr14_+_58765209 0.723 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr3_-_15106806 0.723 NM_022497
MRPS25
mitochondrial ribosomal protein S25
chr1_-_235490801 0.720 NM_001206794
ARID4B
AT rich interactive domain 4B (RBP1-like)
chr9_-_37465384 0.712 NM_014872
ZBTB5
zinc finger and BTB domain containing 5
chr3_+_23987514 0.711 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr1_+_26438267 0.709 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr3_+_23986735 0.701 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr8_+_17396285 0.701 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr4_+_86851425 0.697 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chr11_+_61522860 0.696 NM_013279
C11orf9
chromosome 11 open reading frame 9
chr4_-_125633716 0.696 NM_001167882
NM_020337
ANKRD50

ankyrin repeat domain 50

chr5_+_140186658 0.684 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr5_+_140254930 0.680 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr20_+_30865435 0.678 NM_004798
KIF3B
kinesin family member 3B
chr16_-_71748697 0.678 NM_015020
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2
chr5_+_140213968 0.671 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr17_-_40897025 0.669 NM_001991
EZH1
enhancer of zeste homolog 1 (Drosophila)
chr1_+_2985730 0.666 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr2_-_174828775 0.665 NM_001017371
SP3
Sp3 transcription factor
chr5_+_140220811 0.662 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr11_+_35684342 0.656 NM_017583
TRIM44
tripartite motif containing 44
chr11_+_118307072 0.653 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr10_-_94003002 0.652 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr7_-_2354050 0.650 NM_013321
SNX8
sorting nexin 8
chr10_+_102295572 0.647 NM_017902
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr16_-_2185824 0.644 NM_000296
NM_001009944
PKD1

polycystic kidney disease 1 (autosomal dominant)

chr4_+_86396251 0.640 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr3_-_113160318 0.639 NM_001164496
NM_018338
WDR52

WD repeat domain 52

chr2_-_128100673 0.637 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr4_+_6271558 0.624 NM_001145853
NM_006005
WFS1

Wolfram syndrome 1 (wolframin)

chr21_-_43346780 0.621 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr6_+_126102278 0.612 NM_001199619
NM_001199620
NCOA7

nuclear receptor coactivator 7

chr16_-_3493489 0.606 NM_152457
ZNF597
zinc finger protein 597
chr5_+_133706869 0.606 NM_003337
UBE2B
ubiquitin-conjugating enzyme E2B
chr6_-_143266283 0.604 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr17_-_27621163 0.586 NM_020772
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr19_-_45004482 0.586 NM_013256
ZNF180
zinc finger protein 180
chr15_+_96869156 0.585 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chrX_-_24045302 0.581 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr2_-_225450105 0.581 NM_003590
CUL3
cullin 3
chr5_+_49961732 0.580 NM_001178055
PARP8
poly (ADP-ribose) polymerase family, member 8
chrX_+_119384490 0.580 NM_006777
NM_001184742
ZBTB33

zinc finger and BTB domain containing 33

chr5_+_56110899 0.577 NM_005921
MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr15_+_31619043 0.573 NM_015995
KLF13
Kruppel-like factor 13
chr7_-_6746541 0.570 NM_006956
NM_016265
ZNF12

zinc finger protein 12

chr2_-_48132656 0.569 NM_001190274
FBXO11
F-box protein 11
chr18_-_19284737 0.567 NM_138340
ABHD3
abhydrolase domain containing 3
chr5_+_102201526 0.566 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr1_-_235491494 0.565 NM_016374
NM_031371
ARID4B

AT rich interactive domain 4B (RBP1-like)

chr14_-_53620032 0.560 NM_001160147
NM_001160148
NM_030637
DDHD1


DDHD domain containing 1


chr4_+_57775064 0.553 NM_001193508
REST
RE1-silencing transcription factor
chr5_+_131705353 0.549 NM_003060
SLC22A5
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr5_+_140247767 0.542 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr13_+_78271820 0.538 NM_001242868
SLAIN1
SLAIN motif family, member 1
chrX_-_99986496 0.534 NM_001174068
NM_080737
SYTL4

synaptotagmin-like 4

chr15_+_96876568 0.528 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr6_-_154677868 0.526 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr11_-_77531750 0.517 NM_016578
RSF1
remodeling and spacing factor 1
chr8_-_23540401 0.517 NM_006167
NKX3-1
NK3 homeobox 1
chr9_+_82186846 0.516 NM_007005
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr7_-_152133071 0.515 NM_170606
MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr5_-_133968463 0.514 NM_001033503
NM_016103
SAR1B

SAR1 homolog B (S. cerevisiae)

chr1_-_36851484 0.514 NM_032017
STK40
serine/threonine kinase 40
chr11_+_33279167 0.502 NM_001048200
NM_005734
HIPK3

homeodomain interacting protein kinase 3

chr6_-_154651214 0.497 NM_001130699
IPCEF1
interaction protein for cytohesin exchange factors 1
chr9_-_115652961 0.494 NM_033051
SLC46A2
solute carrier family 46, member 2
chr4_-_16228097 0.492 NM_153365
TAPT1
transmembrane anterior posterior transformation 1
chr2_-_158731622 0.490 NM_001105
ACVR1
activin A receptor, type I
chr12_-_89918531 0.490 NM_003774
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr20_+_33292117 0.490 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr1_+_162467594 0.483 NM_144624
NM_175866
UHMK1

U2AF homology motif (UHM) kinase 1

chrX_-_99987072 0.476 NM_001129896
SYTL4
synaptotagmin-like 4
chr1_-_207224298 0.476 NM_018566
YOD1
YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
chr9_-_127952037 0.474 NM_001123355
NM_001123369
NM_002721
PPP6C


protein phosphatase 6, catalytic subunit


chr4_-_37687932 0.473 NM_001085399
NM_001085400
RELL1

RELT-like 1

chr17_+_73780842 0.470 NM_001080419
UNK
unkempt homolog (Drosophila)
chr4_-_170947428 0.466 NM_021647
MFAP3L
microfibrillar-associated protein 3-like
chr11_-_62473502 0.466 NM_001130702
NM_032667
BSCL2

Berardinelli-Seip congenital lipodystrophy 2 (seipin)

chr17_+_7608413 0.466 NM_001406
EFNB3
ephrin-B3
chr17_+_7184978 0.466 NM_001042
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr2_-_240322620 0.458 NM_006037
HDAC4
histone deacetylase 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.83 3.48e-08 GO:0010468 regulation of gene expression
1.85 4.68e-08 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.83 5.25e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.87 9.16e-08 GO:0051252 regulation of RNA metabolic process
1.66 2.23e-07 GO:0060255 regulation of macromolecule metabolic process
1.84 1.06e-06 GO:0006355 regulation of transcription, DNA-dependent
1.73 1.12e-06 GO:0009889 regulation of biosynthetic process
1.73 1.15e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.73 1.15e-06 GO:0031326 regulation of cellular biosynthetic process
1.60 1.73e-06 GO:0031323 regulation of cellular metabolic process
1.60 2.40e-06 GO:0080090 regulation of primary metabolic process
1.70 3.53e-06 GO:0051171 regulation of nitrogen compound metabolic process
2.70 4.68e-05 GO:0051253 negative regulation of RNA metabolic process
2.58 6.89e-05 GO:0010629 negative regulation of gene expression
2.69 8.40e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.91 1.13e-04 GO:0007399 nervous system development
1.49 1.16e-04 GO:0019222 regulation of metabolic process
2.16 1.32e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.18 3.95e-04 GO:0006351 transcription, DNA-dependent
2.42 7.96e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.39 1.09e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
2.37 1.29e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.33 1.48e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
2.29 1.62e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.71 2.07e-03 GO:0006464 protein modification process
1.40 2.45e-03 GO:0044260 cellular macromolecule metabolic process
2.24 2.72e-03 GO:0009890 negative regulation of biosynthetic process
2.83 4.89e-03 GO:0070647 protein modification by small protein conjugation or removal
2.15 5.87e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.35 7.21e-03 GO:0043170 macromolecule metabolic process
1.97 7.53e-03 GO:0032774 RNA biosynthetic process
2.10 8.07e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.64 8.28e-03 GO:0043412 macromolecule modification
2.05 8.69e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.44 9.57e-03 GO:0007275 multicellular organismal development
2.02 1.33e-02 GO:0009891 positive regulation of biosynthetic process
2.19 1.96e-02 GO:0045893 positive regulation of transcription, DNA-dependent
2.06 2.09e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 2.18e-02 GO:0050794 regulation of cellular process
2.37 2.66e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.93 3.08e-02 GO:0010605 negative regulation of macromolecule metabolic process
3.76 3.25e-02 GO:0007156 homophilic cell adhesion
2.10 3.66e-02 GO:0051254 positive regulation of RNA metabolic process
1.39 3.82e-02 GO:0032502 developmental process
2.08 4.51e-02 GO:0010628 positive regulation of gene expression
1.87 4.71e-02 GO:0009892 negative regulation of metabolic process
2.10 4.87e-02 GO:0007167 enzyme linked receptor protein signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.61 2.43e-15 GO:0005634 nucleus
1.25 1.41e-07 GO:0043229 intracellular organelle
1.25 1.83e-07 GO:0043226 organelle
1.25 2.30e-05 GO:0043231 intracellular membrane-bounded organelle
1.25 2.61e-05 GO:0043227 membrane-bounded organelle
1.17 5.97e-05 GO:0005622 intracellular
1.16 4.23e-04 GO:0044424 intracellular part
1.68 5.41e-04 GO:0031981 nuclear lumen
2.13 1.19e-03 GO:0044451 nucleoplasm part
1.59 1.57e-03 GO:0044428 nuclear part
1.78 1.81e-03 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.06 1.60e-11 GO:0008270 zinc ion binding
1.75 6.25e-11 GO:0003676 nucleic acid binding
1.94 9.39e-11 GO:0003677 DNA binding
1.63 1.07e-09 GO:0046872 metal ion binding
1.62 1.72e-09 GO:0043167 ion binding
1.61 2.80e-09 GO:0043169 cation binding
1.86 6.38e-09 GO:0046914 transition metal ion binding
2.27 7.22e-07 GO:0001071 nucleic acid binding transcription factor activity
2.27 7.22e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
2.18 4.50e-06 GO:0030528 transcription regulator activity
2.35 6.03e-05 GO:0043565 sequence-specific DNA binding
3.05 1.54e-04 GO:0016564 transcription repressor activity
3.41 1.92e-03 GO:0003682 chromatin binding
1.14 3.89e-03 GO:0005488 binding
5.87 5.75e-03 GO:0004879 ligand-dependent nuclear receptor activity
2.35 8.55e-03 GO:0004674 protein serine/threonine kinase activity
5.28 1.37e-02 GO:0008276 protein methyltransferase activity
5.99 1.43e-02 GO:0042054 histone methyltransferase activity
2.06 1.87e-02 GO:0004672 protein kinase activity
5.52 2.61e-02 GO:0003707 steroid hormone receptor activity