Motif ID: AAUCUCA

Z-value: 0.236


Mature miRNA associated with seed AAUCUCA:

NamemiRBase Accession
hsa-miR-216a MIMAT0000273



Activity profile for motif AAUCUCA.

activity profile for motif AAUCUCA


Sorted Z-values histogram for motif AAUCUCA

Sorted Z-values for motif AAUCUCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUCUCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_63638343 0.453 NM_001080537
SNTN
sentan, cilia apical structure protein
chr1_+_78956727 0.337 NM_000959
NM_001039585
PTGFR

prostaglandin F receptor (FP)

chr11_+_111848008 0.318 NM_033425
DIXDC1
DIX domain containing 1
chr21_+_36041687 0.292 NM_053277
CLIC6
chloride intracellular channel 6
chr6_-_33048554 0.281 NM_001242524
NM_001242525
HLA-DPA1

major histocompatibility complex, class II, DP alpha 1

chr5_+_122424840 0.261 NM_001136239
PRDM6
PR domain containing 6
chr3_+_108308336 0.234 NM_014648
DZIP3
DAZ interacting protein 3, zinc finger
chr8_+_17354562 0.230 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr5_+_36608430 0.228 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_+_111807857 0.205 NM_001037954
DIXDC1
DIX domain containing 1
chr6_-_33041266 0.192 NM_033554
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr8_+_17396285 0.186 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr17_+_14204326 0.183 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr17_+_53342320 0.183 NM_002126
HLF
hepatic leukemia factor
chr2_+_85980600 0.171 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr15_-_49255640 0.160 NM_203349
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr9_-_116102533 0.156 NM_001012361
NM_145241
WDR31

WD repeat domain 31

chr10_-_116418056 0.156 NM_002313
ABLIM1
actin binding LIM protein 1
chr10_-_116444374 0.153 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr6_-_80247103 0.142 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr5_+_149109814 0.141 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr10_-_116286661 0.141 NM_006720
ABLIM1
actin binding LIM protein 1
chr5_+_149151502 0.138 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr20_+_51588945 0.127 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr20_+_51801821 0.116 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr1_-_204329043 0.116 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr1_+_236687026 0.106 NM_201544
LGALS8
lectin, galactoside-binding, soluble, 8
chr1_-_86043932 0.100 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr3_-_121553907 0.099 NM_001023570
NM_001023571
IQCB1

IQ motif containing B1

chr1_-_85930733 0.097 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr9_-_15510209 0.096 NM_021144
PSIP1
PC4 and SFRS1 interacting protein 1
chr16_+_69599868 0.094 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr4_-_141348760 0.092 NM_001130675
NM_004362
CLGN

calmegin

chr12_-_50236868 0.091 NM_181708
BCDIN3D
BCDIN3 domain containing
chr20_-_21378046 0.089 NM_033176
NKX2-4
NK2 homeobox 4
chr19_+_13105970 0.089 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr9_-_21031607 0.087 NM_001010915
PTPLAD2
protein tyrosine phosphatase-like A domain containing 2
chr1_+_236686738 0.087 NM_006499
NM_201543
LGALS8

lectin, galactoside-binding, soluble, 8

chr8_+_79578258 0.086 NM_016010
FAM164A
family with sequence similarity 164, member A
chr19_+_54041332 0.083 NM_001079906
NM_001253798
NM_001253799
ZNF331


zinc finger protein 331


chr19_+_54024176 0.081 NM_018555
ZNF331
zinc finger protein 331
chr15_-_77712436 0.080 NM_024776
PEAK1
NKF3 kinase family member
chr2_-_229046313 0.079 NM_001142644
NM_030623
SPHKAP

SPHK1 interactor, AKAP domain containing

chr6_+_30951484 0.078 NM_001010909
MUC21
mucin 21, cell surface associated
chr19_+_54058493 0.078 NM_001079907
ZNF331
zinc finger protein 331
chr1_+_236681513 0.075 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr21_-_43373938 0.074 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr7_-_139876718 0.073 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr20_-_32307889 0.071 NM_007238
NM_183397
PXMP4

peroxisomal membrane protein 4, 24kDa

chr5_+_36606456 0.071 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr17_-_47755340 0.068 NM_001007226
NM_001007227
NM_001007228
NM_001007229
NM_001007230
NM_003563
SPOP





speckle-type POZ protein





chr11_-_132812870 0.068 NM_002545
OPCML
opioid binding protein/cell adhesion molecule-like
chrX_-_20284708 0.065 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr20_+_54933982 0.064 NM_080821
FAM210B
family with sequence similarity 210, member B
chr7_-_105319608 0.064 NM_138495
ATXN7L1
ataxin 7-like 1
chr1_-_89738477 0.064 NM_001134486
NM_052942
GBP5

guanylate binding protein 5

chr8_+_67341244 0.063 NM_015169
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr4_+_3076236 0.063 NM_002111
HTT
huntingtin
chr4_-_88141614 0.062 NM_020803
KLHL8
kelch-like 8 (Drosophila)
chr3_-_160117314 0.060 NM_001190241
NM_020800
IFT80

intraflagellar transport 80 homolog (Chlamydomonas)

chr9_+_35161950 0.059 NM_006377
UNC13B
unc-13 homolog B (C. elegans)
chr7_-_91509979 0.059 NM_006980
MTERF
mitochondrial transcription termination factor
chr5_-_178054001 0.058 NM_020666
CLK4
CDC-like kinase 4
chrX_+_67718623 0.058 NM_001195214
NM_173834
YIPF6

Yip1 domain family, member 6

chr2_-_128100673 0.057 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr5_+_139493689 0.057 NM_005859
PURA
purine-rich element binding protein A
chr2_+_95831176 0.057 NM_001017396
NM_021088
ZNF2

zinc finger protein 2

chr5_+_130506635 0.056 NM_181705
LYRM7
Lyrm7 homolog (mouse)
chr4_+_81952118 0.056 NM_001201
BMP3
bone morphogenetic protein 3
chr5_+_112312392 0.054 NM_001242377
NM_152624
DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

chr10_-_104473957 0.054 NM_004311
ARL3
ADP-ribosylation factor-like 3
chr3_-_160101443 0.052 NM_001190242
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr13_-_31040035 0.048 NM_002128
HMGB1
high mobility group box 1
chr4_+_175204827 0.048 NM_001040157
CEP44
centrosomal protein 44kDa
chr5_-_10761344 0.047 NM_004394
DAP
death-associated protein
chr20_+_43514340 0.047 NM_003404
NM_139323
YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

chr3_+_142375738 0.045 NM_001172312
PLS1
plastin 1
chrX_-_10851808 0.045 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr8_-_57233240 0.043 NM_138969
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr11_-_130184459 0.042 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr2_+_139259349 0.041 NM_001001664
SPOPL
speckle-type POZ protein-like
chrX_-_7895764 0.041 NM_001142389
NM_001172672
PNPLA4

patatin-like phospholipase domain containing 4

chr13_-_21476895 0.041 NM_022459
XPO4
exportin 4
chr1_-_155532322 0.041 NM_018489
ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr1_+_14075861 0.041 NM_001007257
PRDM2
PR domain containing 2, with ZNF domain
chr16_-_12010518 0.041 NM_001130007
GSPT1
G1 to S phase transition 1
chr1_+_28099682 0.041 NM_177424
STX12
syntaxin 12
chr2_-_242212244 0.040 NM_001243900
NM_203346
HDLBP

high density lipoprotein binding protein

chr4_+_52709165 0.040 NM_001040402
NM_015115
DCUN1D4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr12_+_133656984 0.040 NM_003440
ZNF140
zinc finger protein 140
chrX_+_122993536 0.040 NM_001204401
NM_001167
XIAP

X-linked inhibitor of apoptosis

chr11_+_108093558 0.040 NM_000051
ATM
ataxia telangiectasia mutated
chr17_+_46018888 0.040 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr4_+_89299874 0.039 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chrX_-_7895424 0.038 NM_004650
PNPLA4
patatin-like phospholipase domain containing 4
chr12_-_56223400 0.037 NM_032364
DNAJC14
DnaJ (Hsp40) homolog, subfamily C, member 14
chr12_-_89919182 0.037 NM_001199777
POC1B
POC1 centriolar protein homolog B (Chlamydomonas)
chr4_-_66535652 0.037 NM_004439
NM_182472
EPHA5

EPH receptor A5

chr2_-_172967234 0.036 NM_004405
DLX2
distal-less homeobox 2
chr12_-_3982394 0.036 NM_020367
PARP11
poly (ADP-ribose) polymerase family, member 11
chr4_-_85887543 0.036 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr15_-_42500481 0.036 NM_015289
VPS39
vacuolar protein sorting 39 homolog (S. cerevisiae)
chr1_-_205782135 0.035 NM_173854
SLC41A1
solute carrier family 41, member 1
chr4_-_146100793 0.035 NM_001102653
OTUD4
OTU domain containing 4
chr12_+_106994914 0.035 NM_001206691
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chrX_-_10588458 0.034 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr9_+_104161118 0.034 NM_003452
NM_197977
ZNF189

zinc finger protein 189

chr3_+_39093480 0.033 NM_020839
WDR48
WD repeat domain 48
chr5_-_133968463 0.033 NM_001033503
NM_016103
SAR1B

SAR1 homolog B (S. cerevisiae)

chr2_+_175260455 0.032 NM_001193528
NM_024583
SCRN3

secernin 3

chrX_-_10544852 0.032 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr15_+_85291802 0.031 NM_014630
ZNF592
zinc finger protein 592
chr7_+_12250818 0.031 NM_001134232
NM_018374
TMEM106B

transmembrane protein 106B

chr12_+_175872 0.031 NM_001170738
IQSEC3
IQ motif and Sec7 domain 3
chr17_+_6926366 0.031 NM_181844
BCL6B
B-cell CLL/lymphoma 6, member B
chr6_+_110501591 0.030 NM_015891
CDC40
cell division cycle 40 homolog (S. cerevisiae)
chr9_+_4662285 0.030 NM_203453
PPAPDC2
phosphatidic acid phosphatase type 2 domain containing 2
chr21_-_43346780 0.029 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr15_+_22833394 0.029 NM_001102610
NM_052903
TUBGCP5

tubulin, gamma complex associated protein 5

chr19_-_11616689 0.029 NM_138783
ZNF653
zinc finger protein 653
chr8_+_1922030 0.029 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr1_-_153895450 0.028 NM_020699
GATAD2B
GATA zinc finger domain containing 2B
chr18_-_61034350 0.028 NM_002035
KDSR
3-ketodihydrosphingosine reductase
chrX_+_144899330 0.028 NM_001144003
NM_001144004
NM_001144005
NM_032539
SLITRK2



SLIT and NTRK-like family, member 2



chr3_-_125094003 0.027 NM_021964
ZNF148
zinc finger protein 148
chr2_-_16847070 0.027 NM_030797
FAM49A
family with sequence similarity 49, member A
chr20_+_11898536 0.027 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr1_+_177140530 0.026 NM_021165
FAM5B
family with sequence similarity 5, member B
chr11_-_64764388 0.026 NM_138456
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr12_+_11802726 0.026 NM_001987
ETV6
ets variant 6
chrX_-_10645726 0.024 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr2_+_234826042 0.024 NM_024080
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr16_-_12009804 0.024 NM_001130006
NM_002094
GSPT1

G1 to S phase transition 1

chr2_+_111878450 0.024 NM_001204106
NM_001204107
NM_001204108
NM_001204109
NM_001204110
NM_001204111
NM_001204112
NM_001204113
NM_006538
NM_138621
NM_138622
NM_138623
NM_138624
NM_138625
NM_138626
NM_138627
NM_207002
NM_207003
BCL2L11

















BCL2-like 11 (apoptosis facilitator)

















chr16_-_67840464 0.023 NM_020850
RANBP10
RAN binding protein 10
chr18_+_13218777 0.023 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr10_+_46222647 0.023 NM_001169106
NM_001169107
NM_015262
FAM21C


family with sequence similarity 21, member C


chr1_-_109506016 0.023 NM_001048210
NM_015127
CLCC1

AKNAD1
chloride channel CLIC-like 1

AKNA domain containing 1
chr11_+_96123120 0.023 NM_003772
JRKL
jerky homolog-like (mouse)
chr6_-_32163299 0.022 NM_022107
GPSM3
G-protein signaling modulator 3
chr3_+_190105660 0.022 NM_006580
CLDN16
claudin 16
chr1_+_101361589 0.022 NM_001144884
NM_133496
SLC30A7

solute carrier family 30 (zinc transporter), member 7

chr7_+_35840595 0.022 NM_001011553
NM_001242956
NM_001788
SEPT7


septin 7


chr9_+_87283453 0.022 NM_001018064
NM_006180
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr11_-_129062092 0.022 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr10_+_51827654 0.022 NM_001005751
FAM21C
FAM21A
family with sequence similarity 21, member C
family with sequence similarity 21, member A
chr17_+_59477169 0.021 NM_005994
TBX2
T-box 2
chr1_+_52870214 0.021 NM_032864
PRPF38A
PRP38 pre-mRNA processing factor 38 (yeast) domain containing A
chr3_-_195270004 0.021 NM_006241
PPP1R2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr18_+_13611664 0.020 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr5_-_59783885 0.020 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_+_142342265 0.020 NM_002670
PLS1
plastin 1
chr19_-_37407079 0.020 NM_001037232
ZNF829
zinc finger protein 829
chr3_+_142315205 0.019 NM_001145319
PLS1
plastin 1
chr1_+_27719151 0.019 NM_005281
GPR3
G protein-coupled receptor 3
chr9_+_71650478 0.019 NM_000144
NM_001161706
NM_181425
FXN


frataxin


chr18_+_13620866 0.019 NM_004338
NM_181483
C18orf1

chromosome 18 open reading frame 1

chr12_-_51420097 0.019 NM_000617
NM_001174126
NM_001174127
NM_001174128
SLC11A2



solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2



chr1_-_68915631 0.019 NM_000329
RPE65
retinal pigment epithelium-specific protein 65kDa
chr17_-_16118789 0.019 NM_006311
NCOR1
nuclear receptor corepressor 1
chr10_-_61666236 0.018 NM_005436
CCDC6
coiled-coil domain containing 6
chrX_+_144902865 0.018 NM_001144006
NM_001144008
NM_001144009
NM_001144010
SLITRK2



SLIT and NTRK-like family, member 2



chr16_-_18937722 0.018 NM_015092
SMG1
smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr20_+_11871364 0.018 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr1_-_220263150 0.018 NM_006085
BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chr11_-_63536112 0.018 NM_001144936
C11orf95
chromosome 11 open reading frame 95
chrX_-_19688991 0.018 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr1_-_6296034 0.017 NM_012405
ICMT
isoprenylcysteine carboxyl methyltransferase
chr15_-_43662107 0.017 NM_152455
ZSCAN29
zinc finger and SCAN domain containing 29
chr8_+_101162838 0.017 NM_005034
POLR2K
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr5_-_58334936 0.017 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr21_+_38739858 0.017 NM_101395
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr17_-_4167028 0.017 NM_016376
NM_020740
ANKFY1

ankyrin repeat and FYVE domain containing 1

chr20_+_18122867 0.017 NM_020536
CSRP2BP
CSRP2 binding protein
chr1_+_167298280 0.017 NM_001198783
POU2F1
POU class 2 homeobox 1
chr14_+_71374111 0.017 NM_014982
PCNX
pecanex homolog (Drosophila)
chr5_-_34043234 0.017 NM_030945
NM_181435
C1QTNF3

C1q and tumor necrosis factor related protein 3

chr19_-_37406918 0.016 NM_001171979
ZNF829
zinc finger protein 829
chr6_-_134373618 0.016 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr14_-_104313730 0.016 NM_015316
PPP1R13B
protein phosphatase 1, regulatory subunit 13B
chr10_+_60028885 0.016 NM_018464
CISD1
CDGSH iron sulfur domain 1
chr12_+_27863705 0.016 NM_001190864
NM_021821
MRPS35

mitochondrial ribosomal protein S35

chr1_+_167189948 0.016 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr13_-_100624162 0.016 NM_033132
ZIC5
Zic family member 5
chr1_-_207205996 0.015 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr19_+_52901101 0.015 NM_032423
ZNF528
zinc finger protein 528
chr17_-_7382943 0.015 NM_001128833
ZBTB4
zinc finger and BTB domain containing 4
chr10_-_1779669 0.015 NM_018702
ADARB2
adenosine deaminase, RNA-specific, B2
chr8_-_87520981 0.015 NM_016033
FAM82B
family with sequence similarity 82, member B
chr4_-_121993568 0.014 NM_024574
NDNF
neuron-derived neurotrophic factor
chr12_-_12849120 0.014 NM_006143
GPR19
G protein-coupled receptor 19
chr6_+_10555948 0.014 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr1_+_24882565 0.014 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr15_+_65914269 0.013 NM_004727
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr1_-_67896098 0.013 NM_001018067
NM_001018068
NM_001018069
NM_015640
SERBP1



SERPINE1 mRNA binding protein 1



chr1_-_160990971 0.012 NM_016946
F11R
F11 receptor
chr11_-_133402227 0.012 NM_001012393
OPCML
opioid binding protein/cell adhesion molecule-like
chr14_+_73603140 0.012 NM_000021
NM_007318
PSEN1

presenilin 1

chr17_+_37793332 0.011 NM_001165937
NM_001165938
NM_006804
STARD3


StAR-related lipid transfer (START) domain containing 3


chr9_-_14693459 0.011 NM_178566
ZDHHC21
zinc finger, DHHC-type containing 21

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 8.30e-04 GO:0005622 intracellular
1.24 1.04e-03 GO:0044424 intracellular part
1.49 1.71e-03 GO:0005634 nucleus
1.31 4.40e-03 GO:0043231 intracellular membrane-bounded organelle
1.31 4.69e-03 GO:0043227 membrane-bounded organelle
1.27 5.39e-03 GO:0043226 organelle
1.26 9.14e-03 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.91 1.53e-03 GO:0003677 DNA binding
1.66 7.49e-03 GO:0003676 nucleic acid binding