Motif ID: AAUGCCC

Z-value: 0.667


Mature miRNA associated with seed AAUGCCC:

NamemiRBase Accession
hsa-miR-365 MIMAT0000710



Activity profile for motif AAUGCCC.

activity profile for motif AAUGCCC


Sorted Z-values histogram for motif AAUGCCC

Sorted Z-values for motif AAUGCCC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUGCCC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_149363498 2.191 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr20_+_9049660 1.578 NM_001172646
PLCB4
phospholipase C, beta 4
chr20_+_9288446 1.498 NM_000933
PLCB4
phospholipase C, beta 4
chr20_+_9198036 1.405 NM_182797
PLCB4
phospholipase C, beta 4
chr16_+_19467771 1.402 NM_024780
TMC5
transmembrane channel-like 5
chr1_+_61547625 1.343 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr20_-_39317875 1.288 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr1_+_61542928 1.287 NM_001145511
NFIA
nuclear factor I/A
chr6_-_134496006 1.202 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134497069 1.182 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr9_-_117156684 1.132 NM_030767
AKNA
AT-hook transcription factor
chr5_+_149109814 1.120 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr16_+_19422056 1.111 NM_001105248
NM_001105249
TMC5

transmembrane channel-like 5

chr5_+_149151502 1.103 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr1_+_61547388 1.069 NM_001145512
NFIA
nuclear factor I/A
chr12_-_89918531 1.058 NM_003774
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr6_-_134639195 1.042 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134498973 1.038 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr20_+_37434294 0.821 NM_001172735
NM_015568
PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr3_+_23986735 0.820 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr3_+_23987514 0.803 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr3_+_113557679 0.801 NM_017577
GRAMD1C
GRAM domain containing 1C
chr2_+_85980600 0.792 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr1_-_46598250 0.783 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr6_-_46138584 0.765 NM_021572
ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr3_+_113616317 0.763 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr1_-_117753476 0.762 NM_001253850
NM_024626
VTCN1

V-set domain containing T cell activation inhibitor 1

chr17_+_68165660 0.756 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr2_-_158731622 0.701 NM_001105
ACVR1
activin A receptor, type I
chr6_+_16129285 0.691 NM_013262
MYLIP
myosin regulatory light chain interacting protein
chr11_+_2466171 0.686 NM_000218
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr17_+_4613780 0.636 NM_004313
NM_199004
ARRB2

arrestin, beta 2

chr12_+_74931550 0.622 NM_001136262
ATXN7L3B
ataxin 7-like 3B
chr15_-_64995459 0.578 NM_002537
OAZ2
ornithine decarboxylase antizyme 2
chr2_-_158732341 0.568 NM_001111067
ACVR1
activin A receptor, type I
chr2_-_157189040 0.557 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr20_-_3149070 0.540 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr1_+_64936475 0.532 NM_020925
CACHD1
cache domain containing 1
chr9_-_116102533 0.527 NM_001012361
NM_145241
WDR31

WD repeat domain 31

chr5_-_90679115 0.513 NM_020801
ARRDC3
arrestin domain containing 3
chr6_+_24495166 0.512 NM_001080
NM_170740
ALDH5A1

aldehyde dehydrogenase 5 family, member A1

chr17_-_27621163 0.468 NM_020772
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr12_-_89920038 0.466 NM_001199781
NM_001199782
NM_172240
POC1B-GALNT4

POC1B
POC1B-GALNT4 readthrough

POC1 centriolar protein homolog B (Chlamydomonas)
chr3_-_15900928 0.443 NM_015199
ANKRD28
ankyrin repeat domain 28
chr8_+_28351694 0.399 NM_017412
NM_145866
FZD3

frizzled family receptor 3

chr10_-_98346793 0.398 NM_020123
TM9SF3
transmembrane 9 superfamily member 3
chr6_-_111804413 0.391 NM_002912
REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr16_+_69599868 0.387 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr6_+_80340971 0.387 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr13_-_61989654 0.386 NM_022843
PCDH20
protocadherin 20
chr2_-_153573858 0.381 NM_017892
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr9_-_99329092 0.380 NM_001077181
CDC14B
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr5_-_100238870 0.379 NM_175052
NM_005668
ST8SIA4

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

chr19_+_18118921 0.378 NM_015683
ARRDC2
arrestin domain containing 2
chr9_-_100395961 0.377 NM_139246
TSTD2
thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr3_+_14444083 0.364 NM_001134367
NM_001134368
NM_003043
SLC6A6


solute carrier family 6 (neurotransmitter transporter, taurine), member 6


chr11_+_34642587 0.360 NM_001206615
NM_012153
EHF

ets homologous factor

chr12_-_15942350 0.358 NM_004447
EPS8
epidermal growth factor receptor pathway substrate 8
chr10_-_61900659 0.355 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr10_+_16478941 0.352 NM_001001484
NM_030664
PTER

phosphotriesterase related

chr14_-_61190458 0.351 NM_017420
SIX4
SIX homeobox 4
chr8_+_120885899 0.350 NM_022783
DEPTOR
DEP domain containing MTOR-interacting protein
chr10_-_62149487 0.349 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr3_-_15839674 0.343 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr11_+_48002063 0.343 NM_001098503
NM_002843
PTPRJ

protein tyrosine phosphatase, receptor type, J

chr19_+_13105970 0.343 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr19_+_18111923 0.339 NM_001025604
ARRDC2
arrestin domain containing 2
chr3_+_185000714 0.336 NM_001242314
NM_001242317
MAP3K13

mitogen-activated protein kinase kinase kinase 13

chr20_-_62436855 0.334 NM_025224
ZBTB46
zinc finger and BTB domain containing 46
chr1_-_91487769 0.330 NM_032186
NM_201269
ZNF644

zinc finger protein 644

chr2_+_242641310 0.329 NM_032329
ING5
inhibitor of growth family, member 5
chr10_-_62332666 0.323 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr12_+_56414688 0.320 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr3_+_119421865 0.320 NM_033364
C3orf15
chromosome 3 open reading frame 15
chr10_-_62493282 0.312 NM_001204403
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr19_+_50094911 0.299 NM_020719
PRR12
proline rich 12
chrX_+_69674914 0.293 NM_001166278
DLG3
discs, large homolog 3 (Drosophila)
chr9_-_99382073 0.289 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr9_-_135230358 0.285 NM_015046
SETX
senataxin
chr9_-_136933091 0.285 NM_007371
BRD3
bromodomain containing 3
chr17_-_40273304 0.284 NM_021078
KAT2A
K(lysine) acetyltransferase 2A
chr15_-_77712436 0.283 NM_024776
PEAK1
NKF3 kinase family member
chr18_-_44676837 0.277 NM_032124
HDHD2
haloacid dehalogenase-like hydrolase domain containing 2
chr9_-_6007891 0.270 NM_001017969
KIAA2026
KIAA2026
chrX_+_69664704 0.269 NM_021120
DLG3
discs, large homolog 3 (Drosophila)
chr7_+_94285620 0.267 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr5_+_172483285 0.267 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr3_-_11761946 0.264 NM_014667
VGLL4
vestigial like 4 (Drosophila)
chr2_-_190649075 0.261 NM_001128150
NM_016467
ORMDL1

ORM1-like 1 (S. cerevisiae)

chr17_+_58677489 0.260 NM_003620
PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr7_+_94285676 0.260 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr4_-_11430502 0.257 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr1_-_91487013 0.256 NM_016620
ZNF644
zinc finger protein 644
chr13_-_53024730 0.256 NM_016075
VPS36
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr7_+_120590816 0.255 NM_019071
NM_198267
ING3

inhibitor of growth family, member 3

chr17_-_67323185 0.250 NM_172232
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr11_+_94277005 0.250 NM_002033
PIWIL4
FUT4
piwi-like 4 (Drosophila)
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr8_+_104152876 0.249 NM_001024372
NM_024812
BAALC

brain and acute leukemia, cytoplasmic

chr9_+_128024109 0.246 NM_015635
GAPVD1
GTPase activating protein and VPS9 domains 1
chr5_-_132073143 0.243 NM_007054
KIF3A
kinesin family member 3A
chr3_-_11610264 0.243 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr1_+_95558072 0.241 NM_001199679
TMEM56
transmembrane protein 56
chr3_+_185080835 0.240 NM_004721
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr11_+_34654010 0.239 NM_001206616
EHF
ets homologous factor
chrX_+_37545008 0.237 NM_021083
XK
X-linked Kx blood group (McLeod syndrome)
chr8_+_124780742 0.234 NM_144963
FAM91A1
family with sequence similarity 91, member A1
chr11_-_122932844 0.228 NM_006597
NM_153201
HSPA8

heat shock 70kDa protein 8

chr9_-_15510209 0.224 NM_021144
PSIP1
PC4 and SFRS1 interacting protein 1
chr3_-_11685395 0.224 NM_001128219
VGLL4
vestigial like 4 (Drosophila)
chr1_+_89990396 0.221 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr14_-_61115906 0.219 NM_005982
SIX1
SIX homeobox 1
chr2_+_46926049 0.219 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr16_+_75032874 0.218 NM_032268
ZNRF1
zinc and ring finger 1
chr3_-_11623829 0.217 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr7_+_66093854 0.210 NM_001167961
NM_153033
KCTD7

potassium channel tetramerisation domain containing 7

chr2_-_128100673 0.210 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr2_-_202316227 0.209 NM_015049
TRAK2
trafficking protein, kinesin binding 2
chr2_-_56151273 0.209 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr12_+_124118312 0.206 NM_001516
GTF2H3
general transcription factor IIH, polypeptide 3, 34kDa
chr17_-_67311773 0.206 NM_018672
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr1_+_95582827 0.201 NM_152487
TMEM56
transmembrane protein 56
chr15_+_96869156 0.200 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr16_-_66730466 0.197 NM_178818
NM_181521
CMTM4

CKLF-like MARVEL transmembrane domain containing 4

chrX_+_69672110 0.195 NM_020730
DLG3
discs, large homolog 3 (Drosophila)
chr8_-_103876390 0.191 NM_015878
NM_148174
AZIN1

antizyme inhibitor 1

chr6_+_30295007 0.190 NM_172016
TRIM39
tripartite motif containing 39
chr15_-_89089792 0.188 NM_001144074
NM_017996
DET1

de-etiolated homolog 1 (Arabidopsis)

chr5_+_112312392 0.182 NM_001242377
NM_152624
DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

chr1_-_78225319 0.181 NM_015017
NM_201624
NM_201626
USP33


ubiquitin specific peptidase 33


chr15_+_96876568 0.181 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr4_+_88928797 0.178 NM_000297
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr13_-_21476895 0.172 NM_022459
XPO4
exportin 4
chr7_+_22766765 0.169 NM_000600
IL6
interleukin 6 (interferon, beta 2)
chr8_+_67687415 0.169 NM_013257
NM_170709
SGK3

serum/glucocorticoid regulated kinase family, member 3

chr2_+_46524448 0.168 NM_001430
EPAS1
endothelial PAS domain protein 1
chr3_-_33481862 0.168 NM_001128160
NM_014517
UBP1

upstream binding protein 1 (LBP-1a)

chr12_-_7281374 0.167 NM_031491
RBP5
retinol binding protein 5, cellular
chr1_+_90024271 0.166 NM_015350
LRRC8B
leucine rich repeat containing 8 family, member B
chr9_-_14314036 0.165 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr2_+_46926323 0.165 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr12_+_25348138 0.165 NM_001001660
LYRM5
LYR motif containing 5
chr20_+_33292117 0.164 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr7_-_150675236 0.162 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr8_+_67624652 0.162 NM_001033578
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr6_+_30294620 0.161 NM_021253
TRIM39
tripartite motif containing 39
chr12_+_121124922 0.160 NM_014730
MLEC
malectin
chr3_-_33481877 0.157 NM_001128161
UBP1
upstream binding protein 1 (LBP-1a)
chr22_-_41842853 0.157 NM_016272
TOB2
transducer of ERBB2, 2
chr17_+_61627818 0.156 NM_005828
DCAF7
DDB1 and CUL4 associated factor 7
chr2_-_240322620 0.155 NM_006037
HDAC4
histone deacetylase 4
chr19_+_19431622 0.153 NM_015329
MAU2
MAU2 chromatid cohesion factor homolog (C. elegans)
chr1_+_101361589 0.152 NM_001144884
NM_133496
SLC30A7

solute carrier family 30 (zinc transporter), member 7

chr1_+_145096391 0.151 NM_004892
SEC22B
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
chrX_-_54209639 0.150 NM_017848
NM_198456
FAM120C

family with sequence similarity 120C

chr2_+_131862419 0.146 NM_001100623
NM_017958
PLEKHB2

pleckstrin homology domain containing, family B (evectins) member 2

chr6_+_43138919 0.146 NM_003131
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr3_-_112218383 0.146 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr1_-_39338976 0.146 NM_012333
MYCBP
c-myc binding protein
chr1_+_2985730 0.145 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr17_-_16118789 0.145 NM_006311
NCOR1
nuclear receptor corepressor 1
chr14_+_52734430 0.144 NM_000953
PTGDR
prostaglandin D2 receptor (DP)
chr17_-_27278471 0.143 NM_001033561
NM_020889
PHF12

PHD finger protein 12

chr22_+_40440664 0.143 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr3_-_15798057 0.141 NM_001195099
ANKRD28
ankyrin repeat domain 28
chr11_-_27742224 0.140 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr11_+_64073040 0.138 NM_004451
ESRRA
estrogen-related receptor alpha
chr13_-_41240607 0.135 NM_002015
FOXO1
forkhead box O1
chr10_+_181410 0.134 NM_001202464
ZMYND11
zinc finger, MYND-type containing 11
chr12_-_49449106 0.133 NM_003482
MLL2
myeloid/lymphoid or mixed-lineage leukemia 2
chr16_+_14013989 0.133 NM_005236
ERCC4
excision repair cross-complementing rodent repair deficiency, complementation group 4
chr2_-_200322699 0.130 NM_001172509
SATB2
SATB homeobox 2
chr20_-_62284701 0.130 NM_015894
STMN3
stathmin-like 3
chr20_+_60697471 0.128 NM_144703
LSM14B
LSM14B, SCD6 homolog B (S. cerevisiae)
chr6_-_139613114 0.127 NM_153235
TXLNB
taxilin beta
chr11_-_27741192 0.124 NM_001143807
BDNF
brain-derived neurotrophic factor
chr15_+_96875793 0.124 NM_001145156
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr3_+_2140449 0.123 NM_175607
CNTN4
contactin 4
chr11_-_27721975 0.119 NM_001143813
NM_001143814
NM_001709
BDNF


brain-derived neurotrophic factor


chr10_-_32217762 0.119 NM_018287
ARHGAP12
Rho GTPase activating protein 12
chr3_-_47823386 0.118 NM_003074
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr18_-_45456925 0.116 NM_005901
SMAD2
SMAD family member 2
chr14_+_55493837 0.116 NM_080867
NM_199421
SOCS4

suppressor of cytokine signaling 4

chr9_-_127905715 0.116 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr10_+_119000583 0.115 NM_003054
SLC18A2
solute carrier family 18 (vesicular monoamine), member 2
chr1_+_203274646 0.115 NM_006763
BTG2
BTG family, member 2
chr11_-_27723061 0.115 NM_170733
BDNF
brain-derived neurotrophic factor
chrX_-_57021891 0.114 NM_001010862
SPIN3
spindlin family, member 3
chr6_-_109804432 0.113 NM_001164313
NM_014797
ZBTB24

zinc finger and BTB domain containing 24

chr1_-_154600446 0.112 NM_001025107
ADAR
adenosine deaminase, RNA-specific
chr3_+_45730677 0.112 NM_014016
SACM1L
SAC1 suppressor of actin mutations 1-like (yeast)
chr7_+_101460881 0.111 NM_181552
CUX1
cut-like homeobox 1
chr16_-_57219951 0.109 NM_024946
FAM192A
family with sequence similarity 192, member A
chr7_-_141401889 0.108 NM_001080392
KIAA1147
KIAA1147
chr17_-_44302716 0.108 NM_001193465
KIAA1267
KIAA1267
chr12_+_68042493 0.107 NM_003583
NM_006482
DYRK2

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

chr11_-_68609358 0.106 NM_001031847
NM_001876
CPT1A

carnitine palmitoyltransferase 1A (liver)

chr18_-_45457454 0.106 NM_001003652
NM_001135937
SMAD2

SMAD family member 2

chr1_+_236958539 0.106 NM_000254
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase
chr5_-_53606387 0.105 NM_019087
ARL15
ADP-ribosylation factor-like 15
chr12_-_46384365 0.104 NM_004719
SCAF11
SR-related CTD-associated factor 11

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.49 1.58e-06 GO:0051254 positive regulation of RNA metabolic process
3.23 5.45e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
3.05 7.30e-06 GO:0031328 positive regulation of cellular biosynthetic process
3.18 8.33e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.00 1.12e-05 GO:0009891 positive regulation of biosynthetic process
3.08 1.71e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
3.38 2.05e-05 GO:0045893 positive regulation of transcription, DNA-dependent
2.61 2.46e-05 GO:0010604 positive regulation of macromolecule metabolic process
2.52 2.97e-05 GO:0009893 positive regulation of metabolic process
3.23 3.03e-05 GO:0010628 positive regulation of gene expression
2.54 5.34e-05 GO:0031325 positive regulation of cellular metabolic process
3.31 1.90e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.47 2.44e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.81 2.60e-03 GO:0010468 regulation of gene expression
3.64 2.86e-03 GO:0016568 chromatin modification
1.96 3.01e-03 GO:0043412 macromolecule modification
1.98 3.61e-03 GO:0006464 protein modification process
1.61 9.26e-03 GO:0031323 regulation of cellular metabolic process
1.61 1.07e-02 GO:0080090 regulation of primary metabolic process
1.63 1.17e-02 GO:0060255 regulation of macromolecule metabolic process
1.75 1.82e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
3.01 2.29e-02 GO:0006325 chromatin organization
1.53 2.71e-02 GO:0019222 regulation of metabolic process
2.00 2.75e-02 GO:0007399 nervous system development
5.76 2.85e-02 GO:0003001 generation of a signal involved in cell-cell signaling
5.76 2.85e-02 GO:0023061 signal release
2.68 3.08e-02 GO:0051276 chromosome organization
1.71 3.88e-02 GO:0010556 regulation of macromolecule biosynthetic process
4.44 4.29e-02 GO:0016570 histone modification
1.74 4.94e-02 GO:0051252 regulation of RNA metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.49 2.07e-06 GO:0005654 nucleoplasm
1.53 1.50e-05 GO:0005634 nucleus
2.80 1.64e-04 GO:0044451 nucleoplasm part
2.00 2.55e-04 GO:0031981 nuclear lumen
1.25 2.33e-03 GO:0043229 intracellular organelle
1.25 2.66e-03 GO:0043226 organelle
1.80 2.66e-03 GO:0044428 nuclear part
1.19 5.36e-03 GO:0044424 intracellular part
1.26 5.95e-03 GO:0043231 intracellular membrane-bounded organelle
1.26 6.40e-03 GO:0043227 membrane-bounded organelle
1.17 1.47e-02 GO:0005622 intracellular
1.70 1.53e-02 GO:0070013 intracellular organelle lumen
1.67 2.56e-02 GO:0043233 organelle lumen
1.64 3.85e-02 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.40 7.23e-05 GO:0005515 protein binding
2.19 1.10e-02 GO:0001071 nucleic acid binding transcription factor activity
2.19 1.10e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.17 1.89e-02 GO:0005488 binding
2.36 2.19e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
7.98 2.32e-02 GO:0003707 steroid hormone receptor activity
7.54 3.20e-02 GO:0004879 ligand-dependent nuclear receptor activity
2.46 3.52e-02 GO:0004672 protein kinase activity
2.76 3.97e-02 GO:0004674 protein serine/threonine kinase activity
2.07 4.07e-02 GO:0030528 transcription regulator activity