Motif ID: ACUGCAU

Z-value: 0.349


Mature miRNA associated with seed ACUGCAU:

NamemiRBase Accession
hsa-miR-217 MIMAT0000274



Activity profile for motif ACUGCAU.

activity profile for motif ACUGCAU


Sorted Z-values histogram for motif ACUGCAU

Sorted Z-values for motif ACUGCAU



Network of associatons between targets according to the STRING database.



First level regulatory network of ACUGCAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_122526781 0.659 NM_001009571
NM_001167940
NM_017954
CADPS2


Ca++-dependent secretion activator 2


chr17_+_72732958 0.635 NM_001163989
RAB37
RAB37, member RAS oncogene family
chr17_+_72733350 0.632 NM_001006638
NM_001163990
RAB37

RAB37, member RAS oncogene family

chr1_+_205538111 0.568 NM_181644
MFSD4
major facilitator superfamily domain containing 4
chr17_+_72667255 0.536 NM_175738
RAB37
RAB37, member RAS oncogene family
chr4_+_72052354 0.420 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr2_+_39892637 0.336 NM_001167959
TMEM178
transmembrane protein 178
chr2_+_39893021 0.311 NM_152390
TMEM178
transmembrane protein 178
chr16_-_53737713 0.293 NM_001127897
NM_015272
RPGRIP1L

RPGRIP1-like

chr4_+_72204769 0.241 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr20_-_4982133 0.237 NM_005116
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr9_-_127703294 0.232 NM_002077
GOLGA1
golgin A1
chr13_-_37494370 0.213 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr5_-_137911317 0.197 NM_004134
HSPA9
heat shock 70kDa protein 9 (mortalin)
chr8_+_17354562 0.190 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr6_-_52926588 0.189 NM_014920
NM_016513
ICK

intestinal cell (MAK-like) kinase

chr13_-_36705513 0.185 NM_004734
DCLK1
doublecortin-like kinase 1
chr10_-_98346793 0.179 NM_020123
TM9SF3
transmembrane 9 superfamily member 3
chr8_-_56685869 0.179 NM_152417
TMEM68
transmembrane protein 68
chr13_-_36429798 0.166 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr5_+_149109814 0.162 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr5_+_149151502 0.159 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr12_-_63328663 0.158 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr1_-_217262946 0.155 NM_001243506
NM_206594
NM_206595
ESRRG


estrogen-related receptor gamma


chr13_+_27131799 0.153 NM_006646
WASF3
WAS protein family, member 3
chr3_+_14444083 0.152 NM_001134367
NM_001134368
NM_003043
SLC6A6


solute carrier family 6 (neurotransmitter transporter, taurine), member 6


chr13_+_39261172 0.151 NM_207361
FREM2
FRAS1 related extracellular matrix protein 2
chr4_-_23891608 0.150 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr8_+_17396285 0.149 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr1_+_213031596 0.148 NM_014053
FLVCR1
feline leukemia virus subgroup C cellular receptor 1
chr12_+_46123495 0.145 NM_152641
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr11_-_74178593 0.145 NM_005472
KCNE3
potassium voltage-gated channel, Isk-related family, member 3
chr6_+_150690027 0.144 NM_001164694
NM_001164695
NM_203395
IYD


iodotyrosine deiodinase


chr1_-_217311095 0.144 NM_001134285
ESRRG
estrogen-related receptor gamma
chr10_-_61900659 0.144 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr15_+_65822738 0.143 NM_016395
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr14_-_95786095 0.141 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr8_+_76452202 0.140 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr4_-_125633716 0.140 NM_001167882
NM_020337
ANKRD50

ankyrin repeat domain 50

chr10_-_62149487 0.138 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr13_-_30424795 0.137 NM_007106
UBL3
ubiquitin-like 3
chr6_+_126111782 0.136 NM_001122842
NM_001199621
NM_181782
NCOA7


nuclear receptor coactivator 7


chr1_-_216896640 0.135 NM_001243515
NM_001243518
NM_001243519
NM_001438
ESRRG



estrogen-related receptor gamma



chr3_-_101231973 0.134 NM_001077203
NM_020654
SENP7

SUMO1/sentrin specific peptidase 7

chr10_-_62332666 0.133 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr12_-_48745020 0.131 NM_001172682
ZNF641
zinc finger protein 641
chr10_-_62493282 0.130 NM_001204403
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr9_-_15510899 0.130 NM_001128217
NM_033222
PSIP1

PC4 and SFRS1 interacting protein 1

chr20_-_4990913 0.129 NM_203327
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr2_-_24149899 0.129 NM_001242338
NM_017552
ATAD2B

ATPase family, AAA domain containing 2B

chrX_-_108976509 0.128 NM_004458
NM_022977
ACSL4

acyl-CoA synthetase long-chain family member 4

chr12_-_48744553 0.125 NM_001172681
NM_152320
ZNF641

zinc finger protein 641

chr2_+_205410465 0.123 NM_057177
NM_152526
NM_205863
PARD3B


par-3 partitioning defective 3 homolog B (C. elegans)


chr5_-_133304274 0.114 NM_020199
C5orf15
chromosome 5 open reading frame 15
chr6_+_126240369 0.111 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr21_-_36421586 0.110 NM_001754
RUNX1
runt-related transcription factor 1
chr5_+_149340287 0.107 NM_000112
SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr20_+_51588945 0.105 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr8_-_74659082 0.105 NM_001164380
NM_001164381
NM_001164382
NM_001164383
NM_001164385
NM_014393
STAU2





staufen, RNA binding protein, homolog 2 (Drosophila)





chr2_+_139259349 0.105 NM_001001664
SPOPL
speckle-type POZ protein-like
chr20_-_50384899 0.104 NM_006045
ATP9A
ATPase, class II, type 9A
chr2_+_149632772 0.103 NM_004522
KIF5C
kinesin family member 5C
chr12_+_65218351 0.101 NM_015279
TBC1D30
TBC1 domain family, member 30
chr6_-_80247103 0.099 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr16_+_22217369 0.097 NM_013302
EEF2K
eukaryotic elongation factor-2 kinase
chr2_-_60780404 0.097 NM_018014
NM_022893
NM_138559
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chr12_+_74931550 0.094 NM_001136262
ATXN7L3B
ataxin 7-like 3B
chr20_+_51801821 0.094 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr7_-_32534869 0.094 NM_001130710
NM_001139499
LSM5

LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)

chr9_-_21031607 0.093 NM_001010915
PTPLAD2
protein tyrosine phosphatase-like A domain containing 2
chr6_+_138483024 0.092 NM_020340
KIAA1244
KIAA1244
chr6_-_116575170 0.092 NM_021648
TSPYL4
TSPY-like 4
chr14_+_45431333 0.092 NM_015091
FAM179B
family with sequence similarity 179, member B
chr2_-_99347588 0.092 NM_012214
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr2_+_109335906 0.091 NM_006267
RANBP2
RAN binding protein 2
chr7_+_21467572 0.091 NM_003112
SP4
Sp4 transcription factor
chr14_-_89020888 0.090 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr15_-_54051837 0.089 NM_182758
WDR72
WD repeat domain 72
chr5_+_36876838 0.089 NM_015384
NM_133433
NIPBL

Nipped-B homolog (Drosophila)

chr10_-_75910525 0.088 NM_012095
NM_207012
AP3M1

adaptor-related protein complex 3, mu 1 subunit

chr17_+_58677489 0.088 NM_003620
PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr17_-_36105005 0.088 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr2_-_95825262 0.087 NM_032788
ZNF514
zinc finger protein 514
chr18_-_53255734 0.085 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr3_+_41240922 0.085 NM_001098209
NM_001098210
NM_001904
CTNNB1


catenin (cadherin-associated protein), beta 1, 88kDa


chrX_-_129402753 0.084 NM_017666
ZNF280C
zinc finger protein 280C
chr3_+_121613170 0.084 NM_001145998
NM_021082
SLC15A2

solute carrier family 15 (H+/peptide transporter), member 2

chr11_+_94277005 0.084 NM_002033
PIWIL4
FUT4
piwi-like 4 (Drosophila)
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr2_+_86333304 0.083 NM_017952
PTCD3
Pentatricopeptide repeat domain 3
chr1_-_225840660 0.083 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr6_+_126102278 0.083 NM_001199619
NM_001199620
NCOA7

nuclear receptor coactivator 7

chr15_-_77712436 0.082 NM_024776
PEAK1
NKF3 kinase family member
chr7_-_111846384 0.081 NM_014705
DOCK4
dedicator of cytokinesis 4
chr3_+_33840060 0.081 NM_001162429
NM_013374
PDCD6IP

programmed cell death 6 interacting protein

chr14_+_89060729 0.081 NM_207662
ZC3H14
zinc finger CCCH-type containing 14
chrX_-_67653169 0.081 NM_002547
OPHN1
oligophrenin 1
chr2_+_191273012 0.081 NM_017694
MFSD6
major facilitator superfamily domain containing 6
chr13_+_108870713 0.080 NM_032859
ABHD13
abhydrolase domain containing 13
chr2_-_48132656 0.080 NM_001190274
FBXO11
F-box protein 11
chr8_+_92082423 0.080 NM_016023
OTUD6B
OTU domain containing 6B
chr3_-_13114547 0.079 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr5_-_74162614 0.078 NM_015566
FAM169A
family with sequence similarity 169, member A
chr14_+_89029252 0.077 NM_001160103
NM_001160104
NM_024824
NM_207660
ZC3H14



zinc finger CCCH-type containing 14



chr15_+_57210823 0.077 NM_003205
NM_207036
NM_207037
NM_207038
TCF12



transcription factor 12



chr16_-_12010518 0.076 NM_001130007
GSPT1
G1 to S phase transition 1
chr16_+_69599868 0.075 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr1_+_151584514 0.074 NM_030918
SNX27
sorting nexin family member 27
chr4_+_106067031 0.074 NM_017628
TET2
tet methylcytosine dioxygenase 2
chr16_+_14013989 0.074 NM_005236
ERCC4
excision repair cross-complementing rodent repair deficiency, complementation group 4
chr17_-_60142598 0.074 NM_005121
MED13
mediator complex subunit 13
chr3_+_179370779 0.073 NM_003940
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr1_+_180601121 0.073 NM_001135669
NM_004736
XPR1

xenotropic and polytropic retrovirus receptor 1

chr14_+_89029690 0.072 NM_207661
ZC3H14
zinc finger CCCH-type containing 14
chr10_+_25464289 0.071 NM_020752
GPR158
G protein-coupled receptor 158
chr19_-_47617008 0.071 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr11_+_94800055 0.071 NM_032102
SRSF8
serine/arginine-rich splicing factor 8
chrX_-_133931146 0.070 NM_001166599
NM_001166600
NM_001170757
FAM122B


family with sequence similarity 122B


chr12_+_72233486 0.067 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15


chr1_-_153895450 0.064 NM_020699
GATAD2B
GATA zinc finger domain containing 2B
chr20_+_43514340 0.064 NM_003404
NM_139323
YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

chr6_-_119031230 0.064 NM_001178035
CEP85L
centrosomal protein 85kDa-like
chr11_-_74109417 0.064 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chr2_-_219432955 0.064 NM_020935
USP37
ubiquitin specific peptidase 37
chr13_+_73633097 0.063 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr1_+_164528586 0.063 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr21_-_43430448 0.062 NM_001098402
NM_001098403
NM_020727
ZNF295


zinc finger protein 295


chr6_+_116421970 0.062 NM_152729
NT5DC1
5'-nucleotidase domain containing 1
chr1_-_235812994 0.061 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr6_-_79787939 0.061 NM_017934
PHIP
pleckstrin homology domain interacting protein
chr4_+_81952118 0.061 NM_001201
BMP3
bone morphogenetic protein 3
chr8_+_95732101 0.060 NM_181787
DPY19L4
dpy-19-like 4 (C. elegans)
chr12_+_70133179 0.060 NM_175623
NM_175625
RAB3IP

RAB3A interacting protein (rabin3)

chr9_-_135230358 0.059 NM_015046
SETX
senataxin
chrX_+_152599544 0.059 NM_001080485
ZNF275
zinc finger protein 275
chr9_+_115983807 0.058 NM_001859
SLC31A1
solute carrier family 31 (copper transporters), member 1
chr4_-_71705613 0.058 NM_002092
GRSF1
G-rich RNA sequence binding factor 1
chr7_-_32529972 0.058 NM_012322
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr3_-_120461362 0.058 NM_173825
RABL3
RAB, member of RAS oncogene family-like 3
chr7_+_117120016 0.057 NM_000492
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr9_+_33025207 0.056 NM_001539
DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chrX_+_11129405 0.056 NM_001122608
NM_001171991
NM_005333
HCCS


holocytochrome c synthase


chr3_+_197687070 0.055 NM_001136049
NM_033029
LMLN

leishmanolysin-like (metallopeptidase M8 family)

chr6_+_148663728 0.054 NM_015278
SASH1
SAM and SH3 domain containing 1
chr2_+_32390902 0.054 NM_001193513
NM_001193514
NM_001193515
NM_017964
SLC30A6



solute carrier family 30 (zinc transporter), member 6



chr9_+_79056581 0.054 NM_001097634
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr2_-_100721792 0.053 NM_001025108
AFF3
AF4/FMR2 family, member 3
chr17_+_60556247 0.053 NM_001112707
NM_006852
TLK2

tousled-like kinase 2

chr12_+_70172748 0.052 NM_001024647
RAB3IP
RAB3A interacting protein (rabin3)
chr1_-_235814053 0.052 NM_001098721
NM_004485
GNG4

guanine nucleotide binding protein (G protein), gamma 4

chr11_+_26353677 0.052 NM_031418
ANO3
anoctamin 3
chr11_-_75062650 0.052 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr15_+_57511616 0.051 NM_207040
TCF12
transcription factor 12
chrX_+_49644469 0.050 NM_001145073
USP27X
ubiquitin specific peptidase 27, X-linked
chrX_+_67718623 0.050 NM_001195214
NM_173834
YIPF6

Yip1 domain family, member 6

chr1_+_70671331 0.049 NM_001190987
NM_004768
SRSF11

serine/arginine-rich splicing factor 11

chrX_-_20284708 0.049 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr1_+_26438267 0.049 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr20_+_19870209 0.049 NM_018993
RIN2
Ras and Rab interactor 2
chr20_+_19867075 0.049 NM_001242581
RIN2
Ras and Rab interactor 2
chr20_-_48530275 0.048 NM_001135773
SPATA2
spermatogenesis associated 2
chr4_+_57775064 0.048 NM_001193508
REST
RE1-silencing transcription factor
chr22_+_29168628 0.048 NM_173510
CCDC117
coiled-coil domain containing 117
chr4_-_146100793 0.048 NM_001102653
OTUD4
OTU domain containing 4
chr11_+_8102691 0.048 NM_177972
TUB
tubby homolog (mouse)
chr1_+_44115795 0.048 NM_014663
KDM4A
lysine (K)-specific demethylase 4A
chr20_+_12989616 0.048 NM_018327
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr16_+_68573660 0.047 NM_133458
ZFP90
zinc finger protein 90 homolog (mouse)
chr1_+_9294857 0.047 NM_004285
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr4_-_159592979 0.046 NM_001008393
C4orf46
chromosome 4 open reading frame 46
chr4_-_83931973 0.046 NM_001115008
NM_194282
LIN54

lin-54 homolog (C. elegans)

chr17_-_26972173 0.046 NM_014680
KIAA0100
KIAA0100
chr16_-_12009804 0.046 NM_001130006
NM_002094
GSPT1

G1 to S phase transition 1

chr17_-_58603492 0.046 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr13_+_76194569 0.046 NM_005358
LMO7
LIM domain 7
chr14_-_88460008 0.046 NM_001201402
GALC
galactosylceramidase
chr4_-_142054431 0.046 NM_020724
RNF150
ring finger protein 150
chr7_-_79082870 0.045 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_134181369 0.044 NM_152409
C5orf24
chromosome 5 open reading frame 24
chr6_-_166075520 0.044 NM_006661
NM_001130690
PDE10A

phosphodiesterase 10A

chr1_-_51984994 0.042 NM_001981
EPS15
epidermal growth factor receptor pathway substrate 15
chr3_-_160822625 0.042 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr14_-_88459469 0.042 NM_000153
NM_001201401
GALC

galactosylceramidase

chr13_-_21476895 0.042 NM_022459
XPO4
exportin 4
chrX_-_53310748 0.042 NM_001243197
NM_015075
IQSEC2

IQ motif and Sec7 domain 2

chr3_-_120068077 0.042 NM_001099678
LRRC58
leucine rich repeat containing 58
chr1_-_212004113 0.042 NM_014873
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr1_+_198125890 0.042 NM_133494
NEK7
NIMA (never in mitosis gene a)-related kinase 7
chr6_-_166796459 0.042 NM_016098
BRP44L
brain protein 44-like
chr2_+_204103163 0.042 NM_177538
CYP20A1
cytochrome P450, family 20, subfamily A, polypeptide 1
chrX_-_53449610 0.041 NM_006306
SMC1A
structural maintenance of chromosomes 1A
chr8_-_82598517 0.041 NM_001144878
NM_001144879
NM_005536
IMPA1


inositol(myo)-1(or 4)-monophosphatase 1


chr4_-_71705188 0.041 NM_001098477
GRSF1
G-rich RNA sequence binding factor 1
chr15_-_62352565 0.041 NM_001018088
NM_017684
NM_018080
NM_020821
VPS13C



vacuolar protein sorting 13 homolog C (S. cerevisiae)



chr13_+_50571137 0.041 NM_001007278
NM_005798
NM_052811
NM_213590
TRIM13



tripartite motif containing 13



chr1_+_169075869 0.040 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr15_+_44829265 0.040 NM_003758
EIF3J
eukaryotic translation initiation factor 3, subunit J
chr9_+_79074067 0.040 NM_001097633
NM_001490
GCNT1

glucosaminyl (N-acetyl) transferase 1, core 2

chr5_-_168006413 0.040 NM_024594
PANK3
pantothenate kinase 3
chr2_+_86947387 0.039 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr16_-_9057250 0.039 NM_003470
USP7
ubiquitin specific peptidase 7 (herpes virus-associated)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.22 2.66e-04 GO:0033036 macromolecule localization
2.26 2.08e-03 GO:0008104 protein localization
2.41 2.32e-03 GO:0045184 establishment of protein localization
8.58 4.23e-03 GO:0033044 regulation of chromosome organization
2.86 5.12e-03 GO:0034613 cellular protein localization
2.84 5.70e-03 GO:0070727 cellular macromolecule localization
2.31 1.13e-02 GO:0015031 protein transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 1.49e-03 GO:0005622 intracellular
1.18 3.58e-03 GO:0044424 intracellular part
1.37 4.33e-03 GO:0005634 nucleus

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.90 2.43e-03 GO:0019904 protein domain specific binding
1.63 1.70e-02 GO:0000166 nucleotide binding