Motif ID: AGUGCAA

Z-value: 0.466


Mature miRNA associated with seed AGUGCAA:

NamemiRBase Accession
hsa-miR-130a MIMAT0000425
hsa-miR-130b MIMAT0000691
hsa-miR-301a MIMAT0000688
hsa-miR-301b MIMAT0004958
hsa-miR-3666 MIMAT0018088
hsa-miR-4295 MIMAT0016844
hsa-miR-454 MIMAT0003885



Activity profile for motif AGUGCAA.

activity profile for motif AGUGCAA


Sorted Z-values histogram for motif AGUGCAA

Sorted Z-values for motif AGUGCAA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGUGCAA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_34419957 0.871 NM_022073
EGLN3
egl nine homolog 3 (C. elegans)
chr8_+_26371461 0.730 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr8_+_26435339 0.654 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr8_+_75896707 0.565 NM_031461
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr6_+_135502445 0.527 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr11_-_46939908 0.483 NM_002334
LRP4
low density lipoprotein receptor-related protein 4
chr2_-_101767714 0.424 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr2_-_217560247 0.419 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr11_-_70507911 0.404 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr5_+_172068188 0.400 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr2_-_86565205 0.392 NM_001164730
REEP1
receptor accessory protein 1
chr2_-_1748285 0.384 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr3_-_64211111 0.380 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr8_-_23712297 0.369 NM_003155
STC1
stanniocalcin 1
chr3_+_179370779 0.357 NM_003940
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr11_-_70935807 0.353 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr6_-_99797530 0.339 NM_032511
C6orf168
chromosome 6 open reading frame 168
chr1_-_45956795 0.337 NM_007170
TESK2
testis-specific kinase 2
chr2_-_213403280 0.330 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr7_-_105319608 0.322 NM_138495
ATXN7L1
ataxin 7-like 1
chrX_+_17393537 0.322 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chrX_+_17653412 0.317 NM_001136024
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr6_-_170599568 0.316 NM_005618
DLL1
delta-like 1 (Drosophila)
chr11_+_19734821 0.316 NM_001244963
NM_145117
NM_182964
NAV2


neuron navigator 2


chr19_-_1567875 0.309 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr3_+_197687070 0.304 NM_001136049
NM_033029
LMLN

leishmanolysin-like (metallopeptidase M8 family)

chr10_-_126432893 0.297 NM_014661
FAM53B
family with sequence similarity 53, member B
chr2_-_86564632 0.297 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr11_+_19372270 0.295 NM_001111018
NAV2
neuron navigator 2
chr4_-_89744154 0.282 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr11_-_45687135 0.280 NM_003654
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr14_-_60097531 0.272 NM_206852
RTN1
reticulon 1
chr2_+_121103670 0.269 NM_002193
INHBB
inhibin, beta B
chr10_+_35535952 0.267 NM_181698
CCNY
cyclin Y
chr14_+_74111577 0.266 NM_001201366
NM_031427
DNAL1

dynein, axonemal, light chain 1

chr15_+_40532034 0.265 NM_020168
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr14_-_75593720 0.263 NM_033116
NEK9
NIMA (never in mitosis gene a)- related kinase 9
chr20_+_11898536 0.249 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr9_-_14398981 0.247 NM_001190738
NFIB
nuclear factor I/B
chr11_+_36422546 0.242 NM_001160169
PRR5L
proline rich 5 like
chr11_-_8615412 0.242 NM_030906
STK33
serine/threonine kinase 33
chr10_+_6244839 0.238 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr10_+_35625608 0.238 NM_145012
CCNY
cyclin Y
chr13_+_111367328 0.232 NM_005537
ING1
inhibitor of growth family, member 1
chr15_+_40509628 0.228 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr2_+_219745243 0.227 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr10_+_89623091 0.224 NM_000314
PTEN
phosphatase and tensin homolog
chr17_-_56406120 0.221 NM_004758
NM_024418
BZRAP1

benzodiazapine receptor (peripheral) associated protein 1

chr4_-_89978117 0.221 NM_014883
FAM13A
family with sequence similarity 13, member A
chr11_+_36397534 0.220 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr8_-_91094924 0.219 NM_004929
CALB1
calbindin 1, 28kDa
chr10_+_6186758 0.217 NM_001145443
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr12_-_77459198 0.215 NM_203394
E2F7
E2F transcription factor 7
chr18_+_72922725 0.215 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr9_-_14314036 0.214 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr13_+_111365609 0.210 NM_198218
NM_198219
ING1

inhibitor of growth family, member 1

chr1_+_12290056 0.205 NM_015378
NM_018156
VPS13D

vacuolar protein sorting 13 homolog D (S. cerevisiae)

chr7_+_155089483 0.205 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chr1_+_11866206 0.204 NM_001286
NM_021735
NM_021736
NM_021737
CLCN6



chloride channel 6



chr4_+_75230856 0.203 NM_001432
EREG
epiregulin
chr20_+_11871364 0.202 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr11_+_36317724 0.201 NM_001160167
PRR5L
proline rich 5 like
chr1_-_43424834 0.200 NM_006516
SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr11_-_113746205 0.199 NM_020886
USP28
ubiquitin specific peptidase 28
chr10_+_112404104 0.196 NM_001134363
RBM20
RNA binding motif protein 20
chr2_-_180129245 0.194 NM_178123
SESTD1
SEC14 and spectrin domains 1
chr1_+_36273786 0.191 NM_017629
EIF2C4
eukaryotic translation initiation factor 2C, 4
chr3_-_15900928 0.189 NM_015199
ANKRD28
ankyrin repeat domain 28
chr4_-_78740508 0.186 NM_144571
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr14_-_60337350 0.182 NM_021136
RTN1
reticulon 1
chr7_-_50772997 0.181 NM_001001550
GRB10
growth factor receptor-bound protein 10
chr4_-_152147520 0.180 NM_001009555
NM_001128923
SH3D19

SH3 domain containing 19

chrX_-_15353675 0.176 NM_002641
NM_020473
PIGA

phosphatidylinositol glycan anchor biosynthesis, class A

chr12_-_26277807 0.175 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr1_-_25256767 0.174 NM_004350
RUNX3
runt-related transcription factor 3
chr4_+_85504056 0.174 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr7_+_11013453 0.172 NM_014660
PHF14
PHD finger protein 14
chr7_+_91875411 0.171 NM_019004
ANKIB1
ankyrin repeat and IBR domain containing 1
chr1_-_68962726 0.170 NM_001114120
NM_017779
DEPDC1

DEP domain containing 1

chr3_-_15839674 0.169 NM_001195098
ANKRD28
ankyrin repeat domain 28
chrX_-_24665454 0.168 NM_001163265
NM_004845
PCYT1B

phosphate cytidylyltransferase 1, choline, beta

chr5_-_137071703 0.168 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chr14_-_47812394 0.167 NM_182830
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr8_+_70378858 0.165 NM_001128204
NM_015170
SULF1

sulfatase 1

chr9_-_79520878 0.164 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr7_-_50861114 0.163 NM_001001555
GRB10
growth factor receptor-bound protein 10
chr2_-_160761266 0.162 NM_001198759
NM_001198760
NM_002349
LY75-CD302

LY75
LY75-CD302 readthrough

lymphocyte antigen 75
chr22_-_36424397 0.162 NM_001082578
NM_001082579
RBFOX2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr2_-_37544165 0.160 NM_005813
PRKD3
protein kinase D3
chr3_-_145968958 0.159 NM_001128306
NM_001177304
NM_020353
PLSCR4


phospholipid scramblase 4


chrX_+_51075082 0.159 NM_153183
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr12_-_123706393 0.158 NM_022782
MPHOSPH9
M-phase phosphoprotein 9
chr5_+_135468522 0.158 NM_001001419
NM_001001420
NM_005903
SMAD5


SMAD family member 5


chr9_+_101867401 0.157 NM_001130916
NM_004612
TGFBR1

transforming growth factor, beta receptor 1

chr18_-_72921280 0.157 NM_175907
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr2_+_120517206 0.156 NM_002830
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr14_-_45431121 0.156 NM_017658
KLHL28
kelch-like 28 (Drosophila)
chrX_+_53111482 0.154 NM_022117
TSPYL2
TSPY-like 2
chr13_+_111364969 0.153 NM_198217
ING1
inhibitor of growth family, member 1
chr7_-_50800018 0.152 NM_001001549
NM_005311
GRB10

growth factor receptor-bound protein 10

chr3_+_180630054 0.152 NM_001013438
NM_001013439
NM_005087
FXR1


fragile X mental retardation, autosomal homolog 1


chr2_-_122042767 0.150 NM_014553
TFCP2L1
transcription factor CP2-like 1
chr3_-_66550844 0.150 NM_015541
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr4_-_18023358 0.148 NM_001166139
NM_153686
LCORL

ligand dependent nuclear receptor corepressor-like

chr1_+_204485461 0.148 NM_001204171
NM_001204172
NM_002393
MDM4


Mdm4 p53 binding protein homolog (mouse)


chr5_+_112312392 0.147 NM_001242377
NM_152624
DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

chrX_+_38663072 0.146 NM_021242
MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr18_+_19321544 0.146 NM_020774
MIB1
mindbomb homolog 1 (Drosophila)
chr1_-_153895450 0.144 NM_020699
GATAD2B
GATA zinc finger domain containing 2B
chr13_+_32313678 0.140 NM_001166058
NM_130806
RXFP2

relaxin/insulin-like family peptide receptor 2

chr10_+_24497719 0.139 NM_001098501
NM_019590
KIAA1217

KIAA1217

chr12_-_120315074 0.138 NM_001206999
NM_007174
CIT

citron (rho-interacting, serine/threonine kinase 21)

chr6_+_69344939 0.138 NM_001704
BAI3
brain-specific angiogenesis inhibitor 3
chr12_+_109915430 0.137 NM_130466
NM_183415
UBE3B

ubiquitin protein ligase E3B

chr8_-_92053043 0.136 NM_018710
TMEM55A
transmembrane protein 55A
chr2_+_179184970 0.136 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr1_+_244214552 0.136 NM_205768
ZNF238
zinc finger protein 238
chr12_+_56414688 0.136 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr7_+_114562140 0.135 NM_001166345
NM_001166346
NM_199072
MDFIC


MyoD family inhibitor domain containing


chr15_-_64648359 0.135 NM_022048
CSNK1G1
casein kinase 1, gamma 1
chr1_+_244216506 0.134 NM_006352
ZNF238
zinc finger protein 238
chr7_-_106301329 0.133 NM_175884
C7orf74
chromosome 7 open reading frame 74
chr4_+_129730772 0.131 NM_024900
NM_199320
PHF17

PHD finger protein 17

chr3_+_16926451 0.130 NM_001144382
PLCL2
phospholipase C-like 2
chr6_+_64356430 0.130 NM_015153
PHF3
PHD finger protein 3
chr10_-_94050799 0.130 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr3_-_15798057 0.129 NM_001195099
ANKRD28
ankyrin repeat domain 28
chr5_-_58295758 0.128 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_+_7396030 0.127 NM_020546
ADCY2
adenylate cyclase 2 (brain)
chr2_+_131674223 0.126 NM_015320
NM_032995
ARHGEF4

Rho guanine nucleotide exchange factor (GEF) 4

chr22_+_38004914 0.126 NM_001172688
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr15_-_49338496 0.125 NM_001193489
NM_014701
SECISBP2L

SECIS binding protein 2-like

chr18_+_13620866 0.125 NM_004338
NM_181483
C18orf1

chromosome 18 open reading frame 1

chr1_-_169336999 0.124 NM_013330
NM_197972
NME7

non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)

chr22_+_38004454 0.123 NM_001001560
NM_001001561
NM_001172687
NM_013365
GGA1



golgi-associated, gamma adaptin ear containing, ARF binding protein 1



chr12_+_120105656 0.123 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr3_+_140950671 0.122 NM_001037172
NM_152282
ACPL2

acid phosphatase-like 2

chr3_+_61547179 0.122 NM_002841
PTPRG
protein tyrosine phosphatase, receptor type, G
chr3_+_12392993 0.122 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr10_+_97889467 0.120 NM_014803
ZNF518A
zinc finger protein 518A
chr18_+_13218777 0.118 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr12_+_104458235 0.118 NM_013320
HCFC2
host cell factor C2
chr3_+_4535030 0.118 NM_001099952
NM_001168272
NM_002222
ITPR1


inositol 1,4,5-trisphosphate receptor, type 1


chr5_-_59189620 0.118 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr17_+_52978022 0.117 NM_005486
TOM1L1
target of myb1 (chicken)-like 1
chr18_+_13611664 0.116 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr6_+_46097700 0.116 NM_014936
ENPP4
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr2_+_203241044 0.115 NM_001204
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr7_+_23636970 0.114 NM_138771
CCDC126
coiled-coil domain containing 126
chr1_+_26438267 0.114 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr16_-_23521803 0.113 NM_015044
GGA2
golgi-associated, gamma adaptin ear containing, ARF binding protein 2
chr10_+_23983674 0.113 NM_001098500
KIAA1217
KIAA1217
chr4_-_141075232 0.113 NM_018717
MAML3
mastermind-like 3 (Drosophila)
chr2_+_173420776 0.112 NM_002610
PDK1
pyruvate dehydrogenase kinase, isozyme 1
chr18_-_53255734 0.111 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr11_+_120207617 0.111 NM_001198665
NM_015313
ARHGEF12

Rho guanine nucleotide exchange factor (GEF) 12

chr12_-_50419160 0.110 NM_001126103
NM_001126104
NM_013277
RACGAP1


Rac GTPase activating protein 1


chr5_-_58571916 0.110 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_89825292 0.108 NM_198273
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr1_-_243418675 0.108 NM_001042404
NM_001042405
NM_014812
CEP170


centrosomal protein 170kDa


chr11_-_10315680 0.108 NM_030962
SBF2
SET binding factor 2
chr6_-_138893666 0.106 NM_020464
NHSL1
NHS-like 1
chr5_+_56471272 0.105 NM_001127235
GPBP1
GC-rich promoter binding protein 1
chr19_+_10828725 0.105 NM_001005360
NM_001005361
NM_001005362
NM_001190716
NM_004945
DNM2




dynamin 2




chr1_+_185014449 0.104 NM_007212
RNF2
ring finger protein 2
chr3_+_12329332 0.104 NM_005037
NM_138712
PPARG

peroxisome proliferator-activated receptor gamma

chr10_-_104178900 0.104 NM_002779
PSD
pleckstrin and Sec7 domain containing
chr20_-_52199635 0.103 NM_006526
ZNF217
zinc finger protein 217
chr5_-_59783885 0.102 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_+_70405027 0.102 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr6_+_131571298 0.101 NM_004842
NM_138633
AKAP7

A kinase (PRKA) anchor protein 7

chr8_+_27491460 0.101 NM_016240
NM_182826
SCARA3

scavenger receptor class A, member 3

chr5_+_149151502 0.101 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr12_+_1100352 0.101 NM_178039
NM_178040
ERC1

ELKS/RAB6-interacting/CAST family member 1

chr7_+_29603388 0.100 NM_175887
PRR15
proline rich 15
chr20_-_17949067 0.100 NM_014426
SNX5
sorting nexin 5
chr4_+_15004297 0.100 NM_001177381
NM_001177382
NM_001177383
NM_001177384
NM_182485
NM_182646
CPEB2





cytoplasmic polyadenylation element binding protein 2





chr2_-_55646946 0.099 NM_001135597
NM_018084
CCDC88A

coiled-coil domain containing 88A

chr20_+_34742656 0.098 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr11_-_102826433 0.098 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr3_-_52931595 0.097 NM_001198974
NM_198563
TMEM110-MUSTN1
TMEM110
TMEM110-MUSTN1 readthrough
transmembrane protein 110
chr3_+_16974581 0.097 NM_015184
PLCL2
phospholipase C-like 2
chr4_+_106816593 0.096 NM_001033047
NM_001184690
NM_001184691
NM_001184692
NM_001184693
NPNT




nephronectin




chr1_-_212004113 0.096 NM_014873
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr3_+_14444083 0.096 NM_001134367
NM_001134368
NM_003043
SLC6A6


solute carrier family 6 (neurotransmitter transporter, taurine), member 6


chrX_-_108976509 0.096 NM_004458
NM_022977
ACSL4

acyl-CoA synthetase long-chain family member 4

chrX_+_38660653 0.095 NM_001098790
NM_001098791
MID1IP1

MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))

chr7_+_115850546 0.095 NM_015641
TES
testis derived transcript (3 LIM domains)
chr6_-_42419782 0.094 NM_033502
TRERF1
transcriptional regulating factor 1
chr15_-_23086842 0.092 NM_001142275
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr10_+_31610063 0.092 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr10_+_96162185 0.092 NM_015188
TBC1D12
TBC1 domain family, member 12
chr3_+_120627026 0.092 NM_014980
STXBP5L
syntaxin binding protein 5-like
chrX_-_24690740 0.091 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr5_+_86564727 0.091 NM_022650
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr13_-_95364248 0.090 NM_007084
SOX21
SRY (sex determining region Y)-box 21
chr5_-_58334936 0.090 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr2_+_177053306 0.089 NM_024501
HOXD1
homeobox D1
chr10_-_43762366 0.089 NM_145313
RASGEF1A
RasGEF domain family, member 1A
chr5_+_149109814 0.089 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.39 1.25e-07 GO:0050794 regulation of cellular process
1.64 2.17e-07 GO:0031323 regulation of cellular metabolic process
1.63 6.16e-07 GO:0080090 regulation of primary metabolic process
1.73 1.70e-06 GO:0009889 regulation of biosynthetic process
1.74 1.77e-06 GO:0031326 regulation of cellular biosynthetic process
1.77 1.85e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.35 2.38e-06 GO:0050789 regulation of biological process
1.61 6.66e-06 GO:0060255 regulation of macromolecule metabolic process
1.75 7.56e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.54 9.21e-06 GO:0019222 regulation of metabolic process
1.69 3.87e-05 GO:0010468 regulation of gene expression
1.30 5.84e-05 GO:0065007 biological regulation
1.69 2.60e-04 GO:0051252 regulation of RNA metabolic process
1.69 6.31e-04 GO:0006355 regulation of transcription, DNA-dependent
1.60 6.78e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.57 1.61e-03 GO:0051171 regulation of nitrogen compound metabolic process
2.30 2.19e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.49 2.56e-03 GO:0007165 signal transduction
2.25 3.64e-03 GO:0009890 negative regulation of biosynthetic process
2.02 4.16e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.00 5.18e-03 GO:0009892 negative regulation of metabolic process
1.44 5.51e-03 GO:0032502 developmental process
1.64 6.50e-03 GO:0030154 cell differentiation
1.43 7.36e-03 GO:0023052 signaling
1.62 1.02e-02 GO:0048869 cellular developmental process
2.22 1.18e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.25 1.23e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.21 1.32e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.75 1.38e-02 GO:0007399 nervous system development
1.56 1.75e-02 GO:0048519 negative regulation of biological process
2.01 1.85e-02 GO:0048699 generation of neurons
1.69 2.32e-02 GO:0023051 regulation of signaling
1.58 2.65e-02 GO:0048523 negative regulation of cellular process
1.96 2.70e-02 GO:0031324 negative regulation of cellular metabolic process
2.33 2.87e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.49 3.52e-02 GO:0048518 positive regulation of biological process
1.94 3.52e-02 GO:0022008 neurogenesis
2.19 3.68e-02 GO:0010629 negative regulation of gene expression
1.41 4.61e-02 GO:0007275 multicellular organismal development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.28 1.23e-02 GO:0005634 nucleus
1.13 1.71e-02 GO:0005622 intracellular
1.13 3.55e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 3.26e-07 GO:0005488 binding
1.32 3.50e-06 GO:0005515 protein binding
2.09 6.18e-05 GO:0030528 transcription regulator activity
1.68 2.06e-04 GO:0008270 zinc ion binding
2.03 3.56e-04 GO:0001071 nucleic acid binding transcription factor activity
2.03 3.56e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.56 2.32e-03 GO:0046914 transition metal ion binding
1.37 9.62e-03 GO:0046872 metal ion binding
2.65 1.10e-02 GO:0016564 transcription repressor activity
2.34 1.35e-02 GO:0008289 lipid binding
1.36 1.68e-02 GO:0043169 cation binding
1.35 1.90e-02 GO:0043167 ion binding
2.25 3.72e-02 GO:0004674 protein serine/threonine kinase activity