• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: ALX1.p2

Z-value: 0.810

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_-_41254392	1.630	NM_001242589 NM_001242590 NM_018643	TREM1	triggering receptor expressed on myeloid cells 1
chr2_+_102953716	1.474	NM_003856	IL1RL1	interleukin 1 receptor-like 1
chr12_-_10021932	1.424		CLEC2B	C-type lectin domain family 2, member B
chr18_+_47088400	1.294	NM_006033	LIPG	lipase, endothelial
chr4_-_159956332	1.256	NM_152543	C4orf45	chromosome 4 open reading frame 45
chr7_+_74188308	1.230	NM_000265	NCF1 NCF1B	neutrophil cytosolic factor 1 neutrophil cytosolic factor 1B pseudogene
chr1_+_74701070	1.202	NM_015978	TNNI3K	TNNI3 interacting kinase
chr12_-_10022457	1.176	NM_005127	CLEC2B	C-type lectin domain family 2, member B
chr9_-_21217303	1.148	NM_002173	IFNA16	interferon, alpha 16
chr17_-_38859976	1.138	NM_019016	KRT24	keratin 24
chr7_+_37723378	1.136
chr17_+_18647325	1.134	NM_031456	FBXW10	F-box and WD repeat domain containing 10
chr22_+_33196801	1.123	NM_000362	TIMP3	TIMP metallopeptidase inhibitor 3
chr5_-_39270708	1.109	NM_001243093	FYB	FYN binding protein
chr4_-_159093523	1.085		FAM198B	family with sequence similarity 198, member B
chr13_-_60325073	1.019
chr1_+_192127591	0.982	NM_130782	RGS18	regulator of G-protein signaling 18
chr12_+_26348268	0.971	NM_001135823	SSPN	sarcospan (Kras oncogene-associated gene)
chr1_+_115572414	0.923	NM_000549	TSHB	thyroid stimulating hormone, beta
chr7_+_143412938	0.917	NM_001130026	FAM115C	family with sequence similarity 115, member C
chr1_-_149908721	0.905		MTMR11	myotubularin related protein 11
chr9_-_74675498	0.872	NM_001128618	C9orf57	chromosome 9 open reading frame 57
chr12_-_4488707	0.869	NM_020638	FGF23	fibroblast growth factor 23
chr2_-_163008913	0.861	NM_002054	GCG	glucagon
chr5_-_139726173	0.848	NM_001945	HBEGF	heparin-binding EGF-like growth factor
chr7_-_113559048	0.813	NM_002711	PPP1R3A	protein phosphatase 1, regulatory subunit 3A
chr3_+_121774208	0.779	NM_001206924 NM_001206925 NM_175862	CD86	CD86 molecule
chr4_-_159094163	0.758	NM_001031700 NM_001128424	FAM198B	family with sequence similarity 198, member B
chr2_+_210444364	0.718	NM_002374 NM_031845 NM_031847	MAP2	microtubule-associated protein 2
chr10_-_42863435	0.711		LOC441666	zinc finger protein 91 pseudogene
chr3_+_158991035	0.677	NM_001197107 NM_001197108 NM_014575	SCHIP1	schwannomin interacting protein 1
chr7_+_77469446	0.654	NM_001127357 NM_001127359 NM_020432	PHTF2	putative homeodomain transcription factor 2
chr18_+_29769986	0.654	NM_005925	MEP1B	meprin A, beta
chr8_-_15095791	0.638	NM_139167	SGCZ	sarcoglycan, zeta
chrX_+_107288199	0.635	NM_001170553 NM_182607	VSIG1	V-set and immunoglobulin domain containing 1
chr1_-_67266930	0.631	NM_005478	INSL5	insulin-like 5
chr17_+_40703983	0.626	NM_000413	HSD17B1	hydroxysteroid (17-beta) dehydrogenase 1
chr12_-_96390002	0.624	NM_002108	HAL	histidine ammonia-lyase
chr4_-_164534656	0.619	NM_017923	MARCH1	membrane-associated ring finger (C3HC4) 1
chr1_-_247921707	0.615	NM_012353	OR1C1	olfactory receptor, family 1, subfamily C, member 1
chr10_-_23633771	0.614	NM_153714	C10orf67	chromosome 10 open reading frame 67
chr2_+_115822246	0.612	NM_001178037	DPP10	dipeptidyl-peptidase 10 (non-functional)
chr20_+_34556528	0.609	NM_001207076 NM_080834	C20orf152	chromosome 20 open reading frame 152
chr9_+_35042222	0.606	NM_001040410 NM_203299	C9orf131	chromosome 9 open reading frame 131
chr19_-_4535202	0.594	NM_001013706	PLIN5	perilipin 5
chr10_+_49609641	0.593	NM_002750 NM_139046 NM_139047 NM_139049	MAPK8	mitogen-activated protein kinase 8
chrX_+_140982451	0.575	NM_177456	MAGEC3	melanoma antigen family C, 3
chr2_-_215896809	0.571	NM_015657	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12
chr11_+_72975569	0.569	NM_176796 NM_176797	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6
chr9_-_21202201	0.555	NM_021057	IFNA7	interferon, alpha 7
chr19_+_56347943	0.553	NM_134444	NLRP4	NLR family, pyrin domain containing 4
chr19_+_7504573	0.553	NM_001130955	ARHGEF18	Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr4_-_21699317	0.553	NM_001035003	KCNIP4	Kv channel interacting protein 4
chr7_+_102023016	0.553
chrY_-_2655478	0.551	NM_003140	SRY	sex determining region Y
chr16_+_31271327	0.550		ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)
chr6_+_28317687	0.547	NM_001242894 NM_001242895 NM_024493	ZKSCAN3	zinc finger with KRAB and SCAN domains 3
chr12_+_9980076	0.544	NM_016523	KLRF1	killer cell lectin-like receptor subfamily F, member 1
chr4_+_70916158	0.544	NM_002159	HTN1	histatin 1
chr7_-_158611301	0.544		ESYT2	extended synaptotagmin-like protein 2
chr3_+_111717585	0.529	NM_001008272 NM_013259	TAGLN3	transgelin 3
chr15_+_94899163	0.526	NM_001159644	MCTP2	multiple C2 domains, transmembrane 2
chr19_-_48759141	0.525	NM_001184902 NM_001184904	CARD8	caspase recruitment domain family, member 8
chr1_-_244006471	0.519	NM_005465 NM_181690	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
chr4_-_15939949	0.515		FGFBP1	fibroblast growth factor binding protein 1
chrX_+_41548225	0.512	NM_001097579 NM_005300	GPR34	G protein-coupled receptor 34
chr1_+_84647342	0.509	NM_001242862	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr1_+_168250277	0.508	NM_005149	TBX19	T-box 19
chr1_-_200589856	0.506	NM_014875	KIF14	kinesin family member 14
chr3_-_123339423	0.505	NM_053031 NM_053032	MYLK	myosin light chain kinase
chr1_-_149908759	0.502	NM_001145862	MTMR11	myotubularin related protein 11
chr14_-_75330535	0.499	NM_001080408 NM_001243007	PROX2	prospero homeobox 2
chr11_-_115088628	0.494		CADM1	cell adhesion molecule 1
chr3_+_122334461	0.491	NM_152615	PARP15	poly (ADP-ribose) polymerase family, member 15
chr19_-_51872256	0.490	NM_152353	CLDND2	claudin domain containing 2
chr6_-_133084585	0.486	NM_078488	VNN2	vanin 2
chr12_+_20848288	0.485	NM_001145945 NM_001145946 NM_001145944 NM_017435	SLCO1C1	solute carrier organic anion transporter family, member 1C1
chr9_-_99417586	0.485	NM_153698	C9orf21	chromosome 9 open reading frame 21
chr2_+_210444154	0.484		MAP2	microtubule-associated protein 2
chr12_-_11139510	0.476	NM_176890	TAS2R50	taste receptor, type 2, member 50
chr4_+_70796798	0.474	NM_001025104 NM_001890	CSN1S1	casein alpha s1
chr9_-_21368005	0.473	NM_006900	IFNA1 IFNA13	interferon, alpha 1 interferon, alpha 13
chr7_-_7758237	0.470	NM_002947	RPA3	replication protein A3, 14kDa
chr16_+_31271311	0.468		ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)
chr1_+_84630575	0.464	NM_001242860 NM_001242861	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chrX_-_21776158	0.464	NM_014332	SMPX	small muscle protein, X-linked
chr5_-_138718941	0.460		SLC23A1	solute carrier family 23 (nucleobase transporters), member 1
chr1_-_89641722	0.452	NM_207398	GBP7	guanylate binding protein 7
chr12_+_15699277	0.451	NM_030668 NM_030669 NM_030670 NM_030671	PTPRO	protein tyrosine phosphatase, receptor type, O
chr9_-_21350885	0.444	NM_021002	IFNA6	interferon, alpha 6
chr1_-_42776760	0.439
chr16_+_31271277	0.436	NM_000632 NM_001145808	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)
chr2_+_98962617	0.436	NM_001079878 NM_001298	CNGA3	cyclic nucleotide gated channel alpha 3
chrX_+_91090459	0.436	NM_001168360 NM_001168361 NM_001168362 NM_001168363	PCDH11X	protocadherin 11 X-linked
chr4_-_122744978	0.432	NM_001237	CCNA2	cyclin A2
chr18_-_70211722	0.431	NM_182511	CBLN2	cerebellin 2 precursor
chr19_-_7058644	0.430	NM_001164425	MBD3L3	methyl-CpG binding domain protein 3-like 3
chr9_+_111624545	0.429	NM_006687	ACTL7A	actin-like 7A
chr13_-_24007822	0.427	NM_014363	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)
chr13_-_60587298	0.417	NM_030932	DIAPH3	diaphanous homolog 3 (Drosophila)
chr20_-_1472004	0.411		SIRPB2	signal-regulatory protein beta 2
chr19_+_39786964	0.411	NM_172140	IL29	interleukin 29 (interferon, lambda 1)
chr1_+_151735444	0.408	NM_001134939	OAZ3	ornithine decarboxylase antizyme 3
chr19_+_7030593	0.405	NM_001136507	MBD3L5	methyl-CpG binding domain protein 3-like 5
chr13_+_114321469	0.403	NM_002929	GRK1	G protein-coupled receptor kinase 1
chr12_-_11508509	0.402	NM_005039 NM_199353 NM_199354	PRB1	proline-rich protein BstNI subfamily 1
chr18_+_22040592	0.401	NM_001143828 NM_001160166 NM_021624	HRH4	histamine receptor H4
chr7_+_141463896	0.400	NM_016943	TAS2R3	taste receptor, type 2, member 3
chr4_+_158141735	0.400	NM_000826 NM_001083619 NM_001083620	GRIA2	glutamate receptor, ionotropic, AMPA 2
chr8_+_38585703	0.397	NM_001146216	TACC1	transforming, acidic coiled-coil containing protein 1
chr4_+_71248794	0.395	NM_006685	SMR3B	submaxillary gland androgen regulated protein 3B
chr2_+_190540710	0.395	NM_144708	ANKAR	ankyrin and armadillo repeat containing
chr3_+_63263814	0.394	NM_001130003	SYNPR	synaptoporin
chr2_+_234959345	0.394	NM_006944	SPP2	secreted phosphoprotein 2, 24kDa
chr1_+_159409511	0.392	NM_012351	OR10J1	olfactory receptor, family 10, subfamily J, member 1
chr10_-_13276327	0.390	NM_145314	UCMA	upper zone of growth plate and cartilage matrix associated
chr7_-_102283237	0.389	NM_001114403	UPK3BL	uroplakin 3B-like
chr12_-_11422640	0.388	NM_006249	PRB3	proline-rich protein BstNI subfamily 3
chr12_-_11548485	0.383	NM_006248	PRB1 PRB2	proline-rich protein BstNI subfamily 1 proline-rich protein BstNI subfamily 2
chr22_+_20377668	0.383	NM_001242313	TMEM191B	transmembrane protein 191B
chr6_-_110501164	0.379	NM_001024934 NM_001024935 NM_001024936 NM_003931	WASF1	WAS protein family, member 1
chr3_-_38835500	0.375	NM_006514	SCN10A	sodium channel, voltage-gated, type X, alpha subunit
chr3_+_8775485	0.372	NM_001234 NM_033337	CAV3	caveolin 3
chr2_+_204571379	0.371		CD28	CD28 molecule
chr17_-_29641068	0.368		EVI2B	ecotropic viral integration site 2B
chr8_-_117023	0.366	NM_001005504	OR4F21	olfactory receptor, family 4, subfamily F, member 21
chr11_+_12308446	0.365	NM_032867	MICALCL	MICAL C-terminal like
chr1_+_244515936	0.363	NM_001012970	C1orf100	chromosome 1 open reading frame 100
chr13_+_98605928	0.362	NM_002271	IPO5	importin 5
chr7_-_44580857	0.358	NM_001101648 NM_013389	NPC1L1	NPC1 (Niemann-Pick disease, type C1, gene)-like 1
chr19_+_55361897	0.358	NM_001242867 NM_006737	KIR3DL2	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
chr5_+_140782367	0.353	NM_018921 NM_032089	PCDHGA9	protocadherin gamma subfamily A, 9
chr5_-_22853730	0.352	NM_004061	CDH12	cadherin 12, type 2 (N-cadherin 2)
chr17_-_79905108	0.350	NM_001145113	MYADML2	myeloid-associated differentiation marker-like 2
chr1_-_76076762	0.349	NM_001130058 NM_152697	SLC44A5	solute carrier family 44, member 5
chr4_+_109571732	0.348	NM_021227	OSTC	oligosaccharyltransferase complex subunit
chr1_-_152552962	0.348	NM_032563	LCE3D	late cornified envelope 3D
chr19_+_20959109	0.347
chr4_-_38858407	0.346	NM_006068	TLR6	toll-like receptor 6
chrY_+_4924128	0.345	NM_032972 NM_032973	PCDH11X PCDH11Y	protocadherin 11 X-linked protocadherin 11 Y-linked
chr2_+_3705785	0.339	NM_018436	ALLC	allantoicase
chr1_+_78470593	0.338	NM_007034	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr2_-_178787522	0.335	NM_001077358	PDE11A	phosphodiesterase 11A
chr10_+_135160843	0.334	NM_001145201 NM_145202	PRAP1	proline-rich acidic protein 1
chr19_+_54466289	0.334	NM_031895	CACNG8	calcium channel, voltage-dependent, gamma subunit 8
chr12_-_7656285	0.331	NM_004244 NM_203416	CD163	CD163 molecule
chr6_+_26251826	0.330	NM_003524	HIST1H2BH	histone cluster 1, H2bh
chr1_-_203198772	0.328	NM_003465	CHIT1	chitinase 1 (chitotriosidase)
chr12_-_102512277	0.328	NM_024057	NUP37	nucleoporin 37kDa
chr14_-_20797532	0.328	NM_182852 NM_182851	CCNB1IP1	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chrX_+_102965836	0.324	NM_182541	TMEM31	transmembrane protein 31
chr8_+_7783858	0.322	NM_001193630	LOC100132396	zinc finger protein 705D-like
chr4_+_5526882	0.321	NM_005750	C4orf6	chromosome 4 open reading frame 6
chr11_-_59950498	0.320	NM_022349 NM_152851	MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A
chr8_-_37756971	0.319	NM_001002814 NM_025151	RAB11FIP1	RAB11 family interacting protein 1 (class I)
chr1_+_151739130	0.316	NM_016178	OAZ3	ornithine decarboxylase antizyme 3
chr1_-_39347258	0.312	NM_030772	GJA9-MYCBP GJA9	GJA9-MYCBP readthrough gap junction protein, alpha 9, 59kDa
chr19_-_58864820	0.310	NM_130786	A1BG	alpha-1-B glycoprotein
chr18_+_32335939	0.309	NM_001390 NM_001391	DTNA	dystrobrevin, alpha
chr12_-_16759531	0.296	NM_018640	LMO3	LIM domain only 3 (rhombotin-like 2)
chrM_-_9203	0.293
chr17_-_42908178	0.291	NM_001080383	GJC1	gap junction protein, gamma 1, 45kDa
chr9_-_117444368	0.290	NM_001199233	LOC100505478	uncharacterized LOC100505478
chr18_-_14132426	0.289	NM_145287	ZNF519	zinc finger protein 519
chrX_+_82763268	0.288	NM_000307	POU3F4	POU class 3 homeobox 4
chr3_-_196911001	0.288	NM_001204387 NM_001204388	DLG1	discs, large homolog 1 (Drosophila)
chr17_-_2996289	0.287	NM_002548	OR1D2	olfactory receptor, family 1, subfamily D, member 2
chr2_+_167744996	0.287	NM_001079810 NM_001199143 NM_152381	XIRP2	xin actin-binding repeat containing 2
chr4_+_71263598	0.285	NM_021225	PROL1	proline rich, lacrimal 1
chr1_-_197115566	0.281	NM_001206846 NM_018136	ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr7_-_86595203	0.280	NM_152748	KIAA1324L	KIAA1324-like
chr9_+_5231401	0.279	NM_002195	INSL4	insulin-like 4 (placenta)
chr1_+_182419255	0.279	NM_001137669	RGSL1	regulator of G-protein signaling like 1
chr2_+_132480063	0.278	NM_013310	C2orf27A	chromosome 2 open reading frame 27A
chr5_-_119740531	0.277
chr1_+_155853546	0.273		SYT11	synaptotagmin XI
chr4_+_88896868	0.272		SPP1	secreted phosphoprotein 1
chrX_+_91089658	0.271	NM_014522 NM_032968 NM_032969	PCDH11X	protocadherin 11 X-linked
chr6_-_25874439	0.270	NM_001098486 NM_006632	SLC17A3	solute carrier family 17 (sodium phosphate), member 3
chr7_+_94297448	0.268		PEG10	paternally expressed 10
chr6_+_47749774	0.265	NM_181744	OPN5	opsin 5
chr15_+_41099254	0.264	NM_001077268	ZFYVE19	zinc finger, FYVE domain containing 19
chr12_-_11184005	0.264	NM_176885	TAS2R31	taste receptor, type 2, member 31
chr3_-_57326709	0.264	NM_001142733	ASB14	ankyrin repeat and SOCS box containing 14
chr5_-_22853435	0.264		CDH12	cadherin 12, type 2 (N-cadherin 2)
chr8_-_33457491	0.261		DUSP26	dual specificity phosphatase 26 (putative)
chr12_-_54653369	0.257	NM_001127321	CBX5	chromobox homolog 5
chr17_-_29641094	0.253	NM_006495	EVI2B	ecotropic viral integration site 2B
chr10_+_94352960	0.252		KIF11	kinesin family member 11
chr10_-_48806862	0.251	NM_001042357 NM_001042389	PTPN20B PTPN20A	protein tyrosine phosphatase, non-receptor type 20B protein tyrosine phosphatase, non-receptor type 20A
chr19_+_48216600	0.251	NM_014601	EHD2	EH-domain containing 2
chr10_+_94352873	0.250		KIF11	kinesin family member 11
chr14_+_94385239	0.248	NM_001207071 NM_138344	FAM181A	family with sequence similarity 181, member A
chr15_-_34610928	0.247	NM_005135	SLC12A6	solute carrier family 12 (potassium/chloride transporters), member 6
chr9_+_27109138	0.246	NM_000459	TEK	TEK tyrosine kinase, endothelial
chr17_-_3030844	0.246	NM_003555	OR1G1	olfactory receptor, family 1, subfamily G, member 1
chr19_+_7562444	0.245	NM_198534	C19orf45	chromosome 19 open reading frame 45
chr14_-_107013122	0.244		IGHV4-31 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant gamma 1 (G1m marker)
chr5_-_35048239	0.244	NM_031900	AGXT2	alanine--glyoxylate aminotransferase 2
chr11_-_89653575	0.242	NM_001105522	TRIM49L1	tripartite motif containing 49-like 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.35	1.64e-03	GO:0050776	regulation of immune response
1.69	9.24e-03	GO:0002376	immune system process
1.91	1.25e-02	GO:0006955	immune response
1.27	1.52e-02	GO:0032501	multicellular organismal process
6.79	2.48e-02	GO:0060338	regulation of type I interferon-mediated signaling pathway

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.68	5.02e-07	GO:0005576	extracellular region
1.82	2.64e-04	GO:0044421	extracellular region part
1.51	4.12e-04	GO:0044459	plasma membrane part
1.70	8.58e-04	GO:0005887	integral to plasma membrane
1.66	1.71e-03	GO:0031226	intrinsic to plasma membrane
1.29	9.51e-03	GO:0071944	cell periphery
1.28	1.72e-02	GO:0005886	plasma membrane
1.75	2.05e-02	GO:0005615	extracellular space

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.52	9.96e-03	GO:0004872	receptor activity
5.21	1.74e-02	GO:0043498	cell surface binding
1.44	2.06e-02	GO:0004871	signal transducer activity
1.44	2.06e-02	GO:0060089	molecular transducer activity