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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: AR.p2

Z-value: 0.497

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_-_106926393	1.754		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_-_75568232	1.315	NM_000689	ALDH1A1	aldehyde dehydrogenase 1 family, member A1
chr1_-_150738232	1.261		CTSS	cathepsin S
chr1_-_150738255	1.161		CTSS	cathepsin S
chr3_-_58563070	0.968		FAM107A	family with sequence similarity 107, member A
chr3_-_58563490	0.941	NM_001076778 NM_007177	FAM107A	family with sequence similarity 107, member A
chr1_-_150738292	0.665	NM_001199739 NM_004079	CTSS	cathepsin S
chr3_-_120401401	0.662	NM_000187	HGD	homogentisate 1,2-dioxygenase
chr15_-_90349819	0.580		ANPEP	alanyl (membrane) aminopeptidase
chr5_+_140625146	0.534	NM_018935	PCDHB15	protocadherin beta 15
chr14_-_21493858	0.479		NDRG2	NDRG family member 2
chr21_-_35884503	0.440		KCNE1	potassium voltage-gated channel, Isk-related family, member 1
chr1_+_104292278	0.381	NM_001008221	AMY1A	amylase, alpha 1A (salivary)
chr14_-_23623493	0.375	NM_182728	SLC7A8	solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr1_+_104198140	0.353	NM_001008221	AMY1A	amylase, alpha 1A (salivary)
chr5_-_149792276	0.335		CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr1_-_104239071	0.331	NM_001008221	AMY1A	amylase, alpha 1A (salivary)
chr8_+_100025501	0.329		VPS13B	vacuolar protein sorting 13 homolog B (yeast)
chr9_-_117156684	0.327	NM_030767	AKNA	AT-hook transcription factor
chr10_-_62332666	0.325	NM_001204404	ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr15_+_85291521	0.316		ZNF592	zinc finger protein 592
chr10_-_116444112	0.313		ABLIM1	actin binding LIM protein 1
chr4_+_186064416	0.308	NM_001151	SLC25A4	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr5_-_13944588	0.301	NM_001369	DNAH5	dynein, axonemal, heavy chain 5
chr14_-_106518424	0.265		IGH@ IGHA1 IGHG1 IGHG2 IGHM	immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 2 (G2m marker) immunoglobulin heavy constant mu
chr12_-_91505541	0.262	NM_002345	LUM	lumican
chr14_-_106586333	0.260		IGHV4-31	immunoglobulin heavy variable 4-31
chr3_-_120400957	0.226		HGD	homogentisate 1,2-dioxygenase
chr8_+_100025493	0.219	NM_015243 NM_017890 NM_152564 NM_181661	VPS13B	vacuolar protein sorting 13 homolog B (yeast)
chr14_-_21493910	0.205	NM_016250 NM_201535 NM_201536 NM_201537	NDRG2	NDRG family member 2
chr1_-_1149495	0.186	NM_003327	TNFRSF4	tumor necrosis factor receptor superfamily, member 4
chr2_-_105467912	0.173		LOC100506421	uncharacterized LOC100506421
chr20_+_138121	0.173	NM_139074	DEFB127	defensin, beta 127
chr4_+_154178525	0.161		TRIM2	tripartite motif containing 2
chr14_-_106691698	0.158
chrX_-_6453158	0.157	NM_016379	VCX2 VCX3A	variable charge, X-linked 2 variable charge, X-linked 3A
chr10_+_695887	0.157		C10orf108	chromosome 10 open reading frame 108
chrX_-_8139307	0.156	NM_016378	VCX2	variable charge, X-linked 2
chr19_-_54876671	0.153	NM_002287 NM_021706	LAIR1	leukocyte-associated immunoglobulin-like receptor 1
chr7_+_94139331	0.151		CASD1	CAS1 domain containing 1
chr16_-_67970734	0.147	NM_002801	PSMB10	proteasome (prosome, macropain) subunit, beta type, 10
chr14_-_106573348	0.146		IGHV4-31 IGHA1 IGHA2 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr17_-_40346427	0.142	NM_001142622 NM_001142623 NM_032484	GHDC	GH3 domain containing
chr19_+_3708358	0.136		TJP3	tight junction protein 3 (zona occludens 3)
chr20_-_3149070	0.133	NM_014731	ProSAPiP1	ProSAPiP1 protein
chr12_+_51318515	0.124	NM_014033	METTL7A	methyltransferase like 7A
chrX_+_8432870	0.122	NM_001001888	VCX3B VCX3A	variable charge, X-linked 3B variable charge, X-linked 3A
chr1_+_151129104	0.119	NM_001204848 NM_024575	TNFAIP8L2-SCNM1 TNFAIP8L2	TNFAIP8L2-SCNM1 readthrough tumor necrosis factor, alpha-induced protein 8-like 2
chr1_-_27953046	0.112	NM_001042729	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr7_+_142960588	0.109		GSTK1	glutathione S-transferase kappa 1
chr14_-_106994001	0.109		IGHV3-48 IGH@ IGHA1 IGHM	immunoglobulin heavy variable 3-48 immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant mu
chr6_-_154831788	0.107		CNKSR3	CNKSR family member 3
chr7_+_142960502	0.106	NM_001143679 NM_001143680 NM_001143681 NM_015917	GSTK1	glutathione S-transferase kappa 1
chr19_+_35630391	0.102	NM_005031	FXYD1	FXYD domain containing ion transport regulator 1
chr7_-_150945731	0.095	NM_001003801	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr10_-_13544944	0.092	NM_001100912 NM_152751	BEND7	BEN domain containing 7
chr2_-_242576722	0.092	NM_015963	THAP4	THAP domain containing 4
chr7_-_150946031	0.086		SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr9_-_130617009	0.086	NM_000118 NM_001114753	ENG	endoglin
chr9_-_114247024	0.084	NM_001080398	KIAA0368	KIAA0368
chr19_-_15391261	0.083	NM_014299 NM_058243	BRD4	bromodomain containing 4
chr1_-_145715561	0.082	NM_007053	CD160	CD160 molecule
chr13_+_97794050	0.080		MBNL2	muscleblind-like 2 (Drosophila)
chr9_-_124984018	0.079	NM_001242335	LHX6	LIM homeobox 6
chr7_+_150147882	0.077		GIMAP8	GTPase, IMAP family member 8
chrX_+_150345055	0.075	NM_004224	GPR50	G protein-coupled receptor 50
chr2_-_109605668	0.074	NM_022336	EDAR	ectodysplasin A receptor
chr15_+_85291802	0.068	NM_014630	ZNF592	zinc finger protein 592
chr18_+_55816546	0.068	NM_001144965 NM_001144968 NM_001144969 NM_001144971	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr11_+_117070039	0.067	NM_001001522 NM_003186	TAGLN	transgelin
chr15_-_40398286	0.056	NM_001003942 NM_001003943	BMF	Bcl2 modifying factor
chr1_-_202129731	0.053		PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr9_+_131683173	0.053	NM_001100876 NM_174933	PHYHD1	phytanoyl-CoA dioxygenase domain containing 1
chr5_+_67588395	0.047	NM_001242466	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr14_-_106725620	0.047		IGHV4-31 IGHV3-23 IGHA1 IGHG1 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 3-23 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr3_-_50608421	0.046	NM_001171741	C3orf18	chromosome 3 open reading frame 18
chr3_+_184032849	0.044	NM_182917	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr12_+_52347163	0.040	NM_020327	ACVR1B	activin A receptor, type IB
chr16_-_67970651	0.038		PSMB10	proteasome (prosome, macropain) subunit, beta type, 10
chrX_+_118602362	0.037	NM_001152	SLC25A5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr2_-_242576382	0.036		THAP4	THAP domain containing 4
chr6_+_18387580	0.035	NM_182757	RNF144B	ring finger protein 144B
chr14_+_21156922	0.033	NM_001097577 NM_194431	ANG RNASE4	angiogenin, ribonuclease, RNase A family, 5 ribonuclease, RNase A family, 4
chr2_+_88472657	0.032	NM_018271	THNSL2	threonine synthase-like 2 (S. cerevisiae)
chr14_+_76452053	0.031	NM_001102564 NM_052873	IFT43	intraflagellar transport 43 homolog (Chlamydomonas)
chr8_+_62200524	0.030	NM_173519	CLVS1	clavesin 1
chr14_-_107048697	0.029		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_+_65420507	0.026		VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1
chr4_+_166128823	0.025		KLHL2	kelch-like 2, Mayven (Drosophila)
chr12_-_7245048	0.025		C1R	complement component 1, r subcomponent
chr18_+_72166568	0.025		CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)
chr15_+_52311432	0.023		MAPK6	mitogen-activated protein kinase 6
chr1_+_12185955	0.021	NM_152942	TNFRSF8	tumor necrosis factor receptor superfamily, member 8
chr14_-_106692107	0.020		IGHV4-31 IGHA1 IGHD IGHG1 IGHG3	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr5_-_149324282	0.020	NM_000440	PDE6A	phosphodiesterase 6A, cGMP-specific, rod, alpha
chr15_+_52311408	0.019	NM_002748	MAPK6	mitogen-activated protein kinase 6
chr1_+_228395740	0.018	NM_001098623 NM_052843	OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr14_-_106791054	0.017		IGHV4-31 IGHV3-30 IGHA1 IGHD IGHG1 IGHG2 IGHG3 IGHM SCFV	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 3-30 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 2 (G2m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu single-chain Fv fragment
chr14_-_106725232	0.016		ZCWPW2 IGHV3-23 IGKV3-20 IGK@	zinc finger, CW type with PWWP domain 2 immunoglobulin heavy variable 3-23 immunoglobulin kappa variable 3-20 immunoglobulin kappa locus
chr6_-_134373618	0.015	NM_145176	SLC2A12	solute carrier family 2 (facilitated glucose transporter), member 12
chr2_+_231280906	0.015		SP100	SP100 nuclear antigen
chr16_-_787888	0.014		NARFL	nuclear prelamin A recognition factor-like
chr14_-_107199126	0.013		IGHG3	immunoglobulin heavy constant gamma 3 (G3m marker)
chr2_-_231789940	0.012	NM_005683	GPR55	G protein-coupled receptor 55
chrX_+_118602391	0.011		SLC25A5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr15_+_42694587	0.009	NM_173088	CAPN3	calpain 3, (p94)
chr14_+_21467413	0.009	NM_014579	SLC39A2	solute carrier family 39 (zinc transporter), member 2
chr13_+_113777112	0.008	NM_000504	F10	coagulation factor X
chr12_+_125549975	0.008		AACS	acetoacetyl-CoA synthetase
chr5_-_176937337	0.008	NM_001144875 NM_001144876	DOK3	docking protein 3
chr1_-_159684274	0.006	NM_000567	CRP	C-reactive protein, pentraxin-related
chr12_+_125549924	0.005	NM_023928	AACS	acetoacetyl-CoA synthetase
chr1_-_156460390	0.005		MEF2D	myocyte enhancer factor 2D
chr2_+_241544819	0.004	NM_001195381 NM_001195382	GPR35	G protein-coupled receptor 35
chr14_-_74025643	0.004	NM_001220484 NM_203309	HEATR4	HEAT repeat containing 4
chr3_-_190167597	0.004	NM_207316	TMEM207	transmembrane protein 207
chr2_+_135011829	0.002	NM_002410	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr9_+_95736717	0.001	NM_033086	FGD3	FYVE, RhoGEF and PH domain containing 3
chr2_+_242576975	0.001	NM_013325 NM_178326	ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)
chr1_+_200863948	0.001	NM_001142569	C1orf106	chromosome 1 open reading frame 106
chr15_+_59908908	0.001		GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr11_+_45115563	0.000	NM_020229	PRDM11	PR domain containing 11
chr20_-_23731558	0.000	NM_001898	CST1	cystatin SN

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
4.02	1.13e-03	GO:0006955	immune response
2.77	4.10e-02	GO:0002376	immune system process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
34.13	8.92e-09	GO:0003823	antigen binding
170.59	4.50e-03	GO:0015207	adenine transmembrane transporter activity
85.30	2.68e-02	GO:0005345	purine base transmembrane transporter activity
68.24	4.44e-02	GO:0015205	nucleobase transmembrane transporter activity