Motif ID: AUGGCAC

Z-value: 0.252


Mature miRNA associated with seed AUGGCAC:

NamemiRBase Accession
hsa-miR-183 MIMAT0000261



Activity profile for motif AUGGCAC.

activity profile for motif AUGGCAC


Sorted Z-values histogram for motif AUGGCAC

Sorted Z-values for motif AUGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AUGGCAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_57406398 0.579 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr11_-_93276513 0.361 NM_020179
C11orf75
chromosome 11 open reading frame 75
chr11_+_45907046 0.345 NM_005456
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr6_-_130031278 0.215 NM_033515
ARHGAP18
Rho GTPase activating protein 18
chrX_+_16964730 0.206 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr19_-_14316980 0.193 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr19_-_33555757 0.185 NM_033103
RHPN2
rhophilin, Rho GTPase binding protein 2
chr12_+_93771607 0.174 NM_019094
NM_199040
NUDT4

NUDT4P1
nudix (nucleoside diphosphate linked moiety X)-type motif 4

nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1
chr3_+_14444083 0.172 NM_001134367
NM_001134368
NM_003043
SLC6A6


solute carrier family 6 (neurotransmitter transporter, taurine), member 6


chr1_-_94374986 0.159 NM_002061
GCLM
glutamate-cysteine ligase, modifier subunit
chr18_-_53255734 0.156 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr17_+_29718641 0.152 NM_032932
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr1_+_180601121 0.140 NM_001135669
NM_004736
XPR1

xenotropic and polytropic retrovirus receptor 1

chr1_+_227058241 0.139 NM_000447
NM_012486
PSEN2

presenilin 2 (Alzheimer disease 4)

chr10_-_113943467 0.138 NM_001244949
NM_020918
GPAM

glycerol-3-phosphate acyltransferase, mitochondrial

chr2_-_157189040 0.137 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chrX_-_20284708 0.134 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr10_+_70320044 0.134 NM_030625
TET1
tet methylcytosine dioxygenase 1
chr18_+_67956136 0.128 NM_004232
SOCS6
suppressor of cytokine signaling 6
chr9_-_79520878 0.124 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr1_-_169863048 0.124 NM_020423
NM_181093
SCYL3

SCY1-like 3 (S. cerevisiae)

chr2_-_55920947 0.112 NM_033109
PNPT1
polyribonucleotide nucleotidyltransferase 1
chr2_-_161350304 0.107 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr16_-_68482373 0.104 NM_018667
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr15_-_75743776 0.104 NM_015477
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr18_+_29672568 0.103 NM_001191324
NM_198128
RNF138

ring finger protein 138

chr15_-_75744029 0.102 NM_001145358
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr15_-_75748123 0.099 NM_001145357
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr15_-_60884615 0.099 NM_134262
RORA
RAR-related orphan receptor A
chr12_-_12419702 0.098 NM_002336
LRP6
low density lipoprotein receptor-related protein 6
chr5_+_65222381 0.097 NM_001006600
NM_001253697
NM_001253698
NM_001253699
NM_001253701
NM_018695
ERBB2IP





erbb2 interacting protein





chr15_-_61521478 0.096 NM_134261
RORA
RAR-related orphan receptor A
chr8_+_110346549 0.095 NM_001193557
NM_020189
ENY2

enhancer of yellow 2 homolog (Drosophila)

chr13_-_25861608 0.093 NM_004685
MTMR6
myotubularin related protein 6
chr5_+_142150291 0.093 NM_001135608
NM_015071
ARHGAP26

Rho GTPase activating protein 26

chr20_+_9049660 0.091 NM_001172646
PLCB4
phospholipase C, beta 4
chr12_-_131002409 0.091 NM_015347
RIMBP2
RIMS binding protein 2
chr18_+_48556483 0.091 NM_005359
SMAD4
SMAD family member 4
chr10_+_31610063 0.090 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr16_+_85645014 0.088 NM_001134473
KIAA0182
KIAA0182
chr20_+_58515408 0.088 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr14_+_105331581 0.087 NM_001112726
NM_015005
KIAA0284

KIAA0284

chr13_+_108870713 0.086 NM_032859
ABHD13
abhydrolase domain containing 13
chr20_+_9288446 0.086 NM_000933
PLCB4
phospholipase C, beta 4
chr2_+_106361404 0.084 NM_001004722
NM_003581
NCK2

NCK adaptor protein 2

chr15_-_60919642 0.084 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr15_+_57210823 0.083 NM_003205
NM_207036
NM_207037
NM_207038
TCF12



transcription factor 12



chr8_+_6565870 0.083 NM_018361
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr13_-_41240607 0.079 NM_002015
FOXO1
forkhead box O1
chr4_+_148538508 0.079 NM_018241
TMEM184C
transmembrane protein 184C
chr4_+_88928797 0.078 NM_000297
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr20_+_9198036 0.078 NM_182797
PLCB4
phospholipase C, beta 4
chr6_-_52926588 0.076 NM_014920
NM_016513
ICK

intestinal cell (MAK-like) kinase

chr13_+_78271820 0.075 NM_001242868
SLAIN1
SLAIN motif family, member 1
chr6_+_80340971 0.075 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr4_-_125633716 0.074 NM_001167882
NM_020337
ANKRD50

ankyrin repeat domain 50

chr2_-_100106478 0.074 NM_001037872
NM_016316
REV1

REV1 homolog (S. cerevisiae)

chr2_-_222436996 0.073 NM_004438
EPHA4
EPH receptor A4
chr1_-_225840660 0.071 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr15_-_90645704 0.070 NM_002168
IDH2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr13_+_20532906 0.070 NM_001190965
ZMYM2
zinc finger, MYM-type 2
chr1_+_215178884 0.069 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr11_+_11862955 0.069 NM_017944
USP47
ubiquitin specific peptidase 47
chr11_+_8102691 0.068 NM_177972
TUB
tubby homolog (mouse)
chr2_+_106468203 0.068 NM_001004720
NCK2
NCK adaptor protein 2
chr1_-_207224298 0.068 NM_018566
YOD1
YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
chr3_-_113415313 0.068 NM_001009899
KIAA2018
KIAA2018
chr19_-_47975244 0.064 NM_015063
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr1_+_215256559 0.064 NM_001017425
NM_014217
KCNK2

potassium channel, subfamily K, member 2

chr6_+_107811272 0.064 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr2_+_139259349 0.064 NM_001001664
SPOPL
speckle-type POZ protein-like
chr20_+_58508818 0.063 NM_001190826
C20orf177
chromosome 20 open reading frame 177
chr3_+_185000714 0.063 NM_001242314
NM_001242317
MAP3K13

mitogen-activated protein kinase kinase kinase 13

chr1_+_185014449 0.061 NM_007212
RNF2
ring finger protein 2
chr5_-_59783885 0.059 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr10_+_92980322 0.059 NM_032373
PCGF5
polycomb group ring finger 5
chr2_+_42396392 0.059 NM_001145076
NM_019063
EML4

echinoderm microtubule associated protein like 4

chr4_+_170541656 0.059 NM_001243372
NM_001829
NM_173872
CLCN3


chloride channel 3


chr6_-_109415514 0.058 NM_014454
SESN1
sestrin 1
chr16_+_85646923 0.058 NM_014615
KIAA0182
KIAA0182
chr2_+_74273449 0.058 NM_144993
TET3
tet methylcytosine dioxygenase 3
chr13_+_20532788 0.057 NM_003453
NM_197968
NM_001190964
ZMYM2


zinc finger, MYM-type 2


chr17_-_27621163 0.056 NM_020772
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr5_+_102201526 0.052 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr5_-_168006413 0.052 NM_024594
PANK3
pantothenate kinase 3
chr6_+_87865261 0.052 NM_015021
ZNF292
zinc finger protein 292
chr8_-_57123858 0.051 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr6_-_109330190 0.051 NM_001199934
SESN1
sestrin 1
chr15_-_35280496 0.051 NM_014106
ZNF770
zinc finger protein 770
chr15_+_85291802 0.050 NM_014630
ZNF592
zinc finger protein 592
chr9_+_35161950 0.050 NM_006377
UNC13B
unc-13 homolog B (C. elegans)
chr3_+_185080835 0.050 NM_004721
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr2_-_128100673 0.049 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr11_+_125034558 0.049 NM_022062
PKNOX2
PBX/knotted 1 homeobox 2
chr15_+_57511616 0.047 NM_207040
TCF12
transcription factor 12
chr1_-_235490801 0.046 NM_001206794
ARID4B
AT rich interactive domain 4B (RBP1-like)
chr16_+_14164879 0.046 NM_014048
MKL2
MKL/myocardin-like 2
chr18_-_47721165 0.046 NM_001080467
MYO5B
myosin VB
chr14_-_68283293 0.045 NM_015346
ZFYVE26
zinc finger, FYVE domain containing 26
chr10_+_22610138 0.045 NM_005180
BMI1
BMI1 polycomb ring finger oncogene
chr1_-_70820363 0.045 NM_030816
ANKRD13C
ankyrin repeat domain 13C
chr2_+_219263060 0.045 NM_001206878
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr2_+_159313466 0.044 NM_001005476
NM_003628
PKP4

plakophilin 4

chr10_+_31608097 0.043 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr14_+_36295515 0.043 NM_032352
BRMS1L
breast cancer metastasis-suppressor 1-like
chr3_+_150804675 0.042 NM_053002
MED12L
mediator complex subunit 12-like
chr6_-_109330752 0.042 NM_001199933
SESN1
sestrin 1
chr2_-_60780404 0.042 NM_018014
NM_022893
NM_138559
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chr2_+_219264477 0.042 NM_021198
NM_182642
CTDSP1

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1

chr9_-_98270321 0.041 NM_001083604
NM_001083605
PTCH1

patched 1

chr4_+_40058507 0.041 NM_018177
N4BP2
NEDD4 binding protein 2
chr14_+_90863302 0.040 NM_006888
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr9_-_80646150 0.040 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr12_+_79258448 0.039 NM_005639
SYT1
synaptotagmin I
chr6_-_159239269 0.039 NM_003379
EZR
ezrin
chr3_+_140660639 0.039 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr14_+_102228134 0.039 NM_001161725
NM_001161726
PPP2R5C

protein phosphatase 2, regulatory subunit B', gamma

chr6_-_62995852 0.038 NM_152688
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr22_-_21356351 0.038 NM_001008695
NM_030573
THAP7

THAP domain containing 7

chr5_-_58295758 0.037 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_70671331 0.036 NM_001190987
NM_004768
SRSF11

serine/arginine-rich splicing factor 11

chr9_-_98279246 0.036 NM_001083602
NM_001083603
PTCH1

patched 1

chr7_+_20370724 0.036 NM_002214
ITGB8
integrin, beta 8
chr17_-_37607314 0.035 NM_004774
MED1
mediator complex subunit 1
chr12_+_64798050 0.035 NM_007235
XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr4_+_15004297 0.034 NM_001177381
NM_001177382
NM_001177383
NM_001177384
NM_182485
NM_182646
CPEB2





cytoplasmic polyadenylation element binding protein 2





chr8_-_24814028 0.033 NM_006158
NEFL
neurofilament, light polypeptide
chr8_+_120220554 0.033 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr18_+_29671817 0.033 NM_016271
RNF138
ring finger protein 138
chr5_-_58571916 0.033 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_69063768 0.032 NM_001127231
NM_001127232
NM_015570
AUTS2


autism susceptibility candidate 2


chr11_+_63655986 0.031 NM_017490
MARK2
MAP/microtubule affinity-regulating kinase 2
chr7_-_16685360 0.031 NM_020319
ANKMY2
ankyrin repeat and MYND domain containing 2
chr17_-_16118789 0.031 NM_006311
NCOR1
nuclear receptor corepressor 1
chr9_+_132934685 0.031 NM_014286
NCS1
neuronal calcium sensor 1
chr1_-_93257950 0.030 NM_005665
EVI5
ecotropic viral integration site 5
chr13_+_78315294 0.030 NM_001242869
NM_001242870
NM_001242871
NM_144595
SLAIN1



SLAIN motif family, member 1



chr5_-_59189620 0.030 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58334936 0.029 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr17_+_53342320 0.029 NM_002126
HLF
hepatic leukemia factor
chr7_-_8301767 0.029 NM_001136020
ICA1
islet cell autoantigen 1, 69kDa
chr10_+_114709963 0.029 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr17_-_60142598 0.028 NM_005121
MED13
mediator complex subunit 13
chr9_-_98269686 0.028 NM_001083606
PTCH1
patched 1
chr12_+_79257772 0.028 NM_001135805
SYT1
synaptotagmin I
chr9_-_98270830 0.028 NM_000264
PTCH1
patched 1
chr7_+_101460881 0.028 NM_181552
CUX1
cut-like homeobox 1
chr21_-_27945267 0.027 NM_052954
CYYR1
cysteine/tyrosine-rich 1
chr5_-_32174397 0.027 NM_022130
GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr9_-_98269480 0.027 NM_001083607
PTCH1
patched 1
chr17_+_27717942 0.027 NM_020791
NM_025142
TAOK1

TAO kinase 1

chr12_+_27397077 0.026 NM_015000
STK38L
serine/threonine kinase 38 like
chr11_-_60928878 0.026 NM_017966
VPS37C
vacuolar protein sorting 37 homolog C (S. cerevisiae)
chr7_+_35840595 0.023 NM_001011553
NM_001242956
NM_001788
SEPT7


septin 7


chr1_-_153895450 0.023 NM_020699
GATAD2B
GATA zinc finger domain containing 2B
chr8_-_141645603 0.023 NM_001164623
NM_012154
EIF2C2

eukaryotic translation initiation factor 2C, 2

chr11_-_116968986 0.023 NM_025164
SIK3
SIK family kinase 3
chr3_-_71632741 0.022 NM_001244808
NM_001012505
NM_001244810
NM_032682
FOXP1



forkhead box P1



chr1_-_235491494 0.021 NM_016374
NM_031371
ARID4B

AT rich interactive domain 4B (RBP1-like)

chr9_-_135819995 0.021 NM_000368
NM_001162426
NM_001162427
TSC1


tuberous sclerosis 1


chr4_-_2263706 0.021 NM_006454
MXD4
MAX dimerization protein 4
chr2_+_46769821 0.020 NM_012249
RHOQ
ras homolog gene family, member Q
chr10_-_114206640 0.020 NM_022494
ZDHHC6
zinc finger, DHHC-type containing 6
chr3_+_38495778 0.020 NM_001106
ACVR2B
activin A receptor, type IIB
chr4_-_129209983 0.019 NM_006320
PGRMC2
progesterone receptor membrane component 2
chr9_-_114247024 0.019 NM_001080398
KIAA0368
KIAA0368
chr12_+_79439432 0.018 NM_001135806
SYT1
synaptotagmin I
chr20_+_3451615 0.018 NM_001207047
NM_139321
NM_139322
ATRN


attractin


chr1_-_67896098 0.018 NM_001018067
NM_001018068
NM_001018069
NM_015640
SERBP1



SERPINE1 mRNA binding protein 1



chr11_+_12695851 0.017 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr1_-_151798552 0.017 NM_001001523
RORC
RAR-related orphan receptor C
chr12_-_16760935 0.017 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr7_-_8302141 0.016 NM_004968
ICA1
islet cell autoantigen 1, 69kDa
chr5_+_153418518 0.015 NM_001135037
NM_001242336
NM_005927
MFAP3


microfibrillar-associated protein 3


chr10_-_25012543 0.015 NM_020824
ARHGAP21
Rho GTPase activating protein 21
chr7_-_71802207 0.014 NM_001017440
CALN1
calneuron 1
chr11_-_47198675 0.014 NM_001242832
NM_032389
ARFGAP2

ADP-ribosylation factor GTPase activating protein 2

chr1_-_160254923 0.014 NM_001193644
NM_002857
PEX19

peroxisomal biogenesis factor 19

chr5_-_137071703 0.014 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chr2_+_206547131 0.013 NM_003872
NM_018534
NM_201264
NM_201266
NM_201267
NM_201279
NRP2





neuropilin 2





chr12_-_16759531 0.013 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr17_-_16097882 0.013 NM_001190438
NM_001190440
NCOR1

nuclear receptor corepressor 1

chr7_-_37956515 0.013 NM_003014
SFRP4
secreted frizzled-related protein 4
chr1_-_236767787 0.012 NM_018072
HEATR1
HEAT repeat containing 1
chr18_+_32073245 0.012 NM_001198945
NM_001392
NM_032975
NM_032979
DTNA



dystrobrevin, alpha



chr19_+_5623045 0.011 NM_001201338
NM_001201339
NM_001201340
NM_002967
SAFB



scaffold attachment factor B



chr6_-_3445198 0.011 NM_021945
SLC22A23
solute carrier family 22, member 23
chr1_+_204485461 0.011 NM_001204171
NM_001204172
NM_002393
MDM4


Mdm4 p53 binding protein homolog (mouse)


chr6_+_88032289 0.011 NM_001042493
NM_020425
C6orf162

chromosome 6 open reading frame 162

chr4_-_11430502 0.010 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr4_-_78740508 0.010 NM_144571
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr17_-_74733419 0.010 NM_001195427
NM_003016
SRSF2

serine/arginine-rich splicing factor 2

chr5_+_271700 0.010 NM_013232
PDCD6
programmed cell death 6
chr12_+_72148653 0.010 NM_014999
RAB21
RAB21, member RAS oncogene family
chr10_-_75910525 0.009 NM_012095
NM_207012
AP3M1

adaptor-related protein complex 3, mu 1 subunit

chr16_+_9185534 0.009 NM_014117
C16orf72
chromosome 16 open reading frame 72
chr6_-_132834165 0.009 NM_003569
STX7
syntaxin 7
chr10_+_22605300 0.007 NM_001204062
NM_012071
COMMD3-BMI1
COMMD3
COMMD3-BMI1 readthrough
COMM domain containing 3
chr9_+_129622935 0.007 NM_001099270
ZBTB34
zinc finger and BTB domain containing 34
chr6_+_131148544 0.007 NM_001195597
LOC100507203
uncharacterized LOC100507203

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.78 3.17e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
4.01 1.03e-02 GO:0048598 embryonic morphogenesis
1.39 1.25e-02 GO:0065007 biological regulation
8.55 1.58e-02 GO:0021915 neural tube development
1.88 1.91e-02 GO:0010468 regulation of gene expression
2.97 2.06e-02 GO:0009790 embryo development
1.41 2.80e-02 GO:0050794 regulation of cellular process
1.39 2.89e-02 GO:0050789 regulation of biological process
20.56 3.25e-02 GO:0070303 negative regulation of stress-activated protein kinase signaling cascade
3.05 4.13e-02 GO:0010629 negative regulation of gene expression

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.27 7.26e-05 GO:0044424 intracellular part
1.26 1.02e-04 GO:0005622 intracellular
1.12 5.18e-03 GO:0044464 cell part
1.12 5.22e-03 GO:0005623 cell
1.48 7.21e-03 GO:0005634 nucleus
1.28 8.05e-03 GO:0043229 intracellular organelle
1.27 8.93e-03 GO:0043226 organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.49 2.10e-05 GO:0005515 protein binding
1.25 6.85e-05 GO:0005488 binding
1.65 2.76e-03 GO:0046872 metal ion binding
1.64 3.96e-03 GO:0043169 cation binding
1.63 4.28e-03 GO:0043167 ion binding
3.47 5.86e-03 GO:0019904 protein domain specific binding
97.62 1.96e-02 GO:0071535 RING-like zinc finger domain binding