Motif ID: CACAGUG

Z-value: 0.813


Mature miRNA associated with seed CACAGUG:

NamemiRBase Accession
hsa-miR-128 MIMAT0000424



Activity profile for motif CACAGUG.

activity profile for motif CACAGUG


Sorted Z-values histogram for motif CACAGUG

Sorted Z-values for motif CACAGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of CACAGUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_13590624 1.670 NM_001004019
NM_001998
FBLN2

fibulin 2

chr13_-_37494370 1.641 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr3_+_13610239 1.632 NM_001165035
FBLN2
fibulin 2
chr6_-_24911194 1.520 NM_014722
FAM65B
family with sequence similarity 65, member B
chr19_-_7293876 1.179 NM_000208
NM_001079817
INSR

insulin receptor

chr14_+_67999915 1.176 NM_020715
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr5_-_57755787 1.173 NM_001252226
NM_006622
PLK2

polo-like kinase 2

chr1_-_75139421 1.172 NM_001002912
C1orf173
chromosome 1 open reading frame 173
chr14_+_56584854 1.083 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr1_-_92351613 1.076 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr19_+_32897021 1.074 NM_207325
DPY19L3
dpy-19-like 3 (C. elegans)
chr20_-_7921068 1.066 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr19_+_32896515 1.026 NM_001172774
DPY19L3
dpy-19-like 3 (C. elegans)
chr14_-_89883306 1.025 NM_005197
FOXN3
forkhead box N3
chr6_-_56112315 1.004 NM_030820
COL21A1
collagen, type XXI, alpha 1
chr14_+_100259445 0.998 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chr8_+_1922030 0.984 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr12_-_63328663 0.980 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr14_-_90085325 0.977 NM_001085471
FOXN3
forkhead box N3
chr1_-_92371558 0.951 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr9_-_130742803 0.950 NM_001035254
FAM102A
family with sequence similarity 102, member A
chr9_-_130712866 0.912 NM_203305
FAM102A
family with sequence similarity 102, member A
chr4_-_107957452 0.868 NM_014421
DKK2
dickkopf 2 homolog (Xenopus laevis)
chr20_-_3149070 0.860 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr15_+_73344824 0.858 NM_001172623
NM_001172624
NM_002499
NEO1


neogenin 1


chr17_+_57408907 0.833 NM_001005404
YPEL2
yippee-like 2 (Drosophila)
chr20_-_20693122 0.831 NM_020343
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr1_+_61542928 0.805 NM_001145511
NFIA
nuclear factor I/A
chr15_+_29213839 0.794 NM_001130414
NM_005503
APBA2

amyloid beta (A4) precursor protein-binding, family A, member 2

chr20_-_41818464 0.784 NM_007050
NM_133170
PTPRT

protein tyrosine phosphatase, receptor type, T

chr5_+_50678957 0.763 NM_002202
ISL1
ISL LIM homeobox 1
chr5_-_160279045 0.758 NM_025153
ATP10B
ATPase, class V, type 10B
chr8_+_40010986 0.755 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr1_+_61547625 0.753 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr6_+_126111782 0.739 NM_001122842
NM_001199621
NM_181782
NCOA7


nuclear receptor coactivator 7


chr14_+_92789536 0.733 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr7_-_37024664 0.728 NM_001039459
ELMO1
engulfment and cell motility 1
chr5_+_76506705 0.725 NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719
PDE8B




phosphodiesterase 8B




chr21_-_43373938 0.725 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr22_-_39240016 0.724 NM_014293
NPTXR
neuronal pentraxin receptor
chr8_+_76452202 0.718 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr5_-_111093792 0.711 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr6_+_133562488 0.709 NM_004100
NM_172103
NM_172105
EYA4


eyes absent homolog 4 (Drosophila)


chr5_-_111092918 0.707 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr5_-_111093030 0.700 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr17_+_12569206 0.697 NM_001146312
NM_153604
MYOCD

myocardin

chr7_-_37393271 0.696 NM_001206482
ELMO1
engulfment and cell motility 1
chr19_+_51815095 0.687 NM_001101372
IGLON5
IgLON family member 5
chr7_-_37488554 0.686 NM_014800
ELMO1
engulfment and cell motility 1
chr10_+_81107219 0.685 NM_005729
PPIF
peptidylprolyl isomerase F
chr14_+_92790151 0.671 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr5_-_121412805 0.649 NM_001178102
LOX
lysyl oxidase
chr3_-_13114547 0.643 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr5_-_111093251 0.639 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr5_-_111312522 0.638 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr15_+_76352270 0.638 NM_152335
C15orf27
chromosome 15 open reading frame 27
chr16_-_68482373 0.634 NM_018667
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr14_-_39901619 0.624 NM_203301
FBXO33
F-box protein 33
chr10_-_21463019 0.619 NM_001173484
NM_213569
NEBL

nebulette

chr17_-_41985112 0.618 NM_005374
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr11_-_30038487 0.609 NM_002233
KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr7_-_37488894 0.608 NM_001206480
ELMO1
engulfment and cell motility 1
chr10_-_113943467 0.605 NM_001244949
NM_020918
GPAM

glycerol-3-phosphate acyltransferase, mitochondrial

chr1_+_180601121 0.588 NM_001135669
NM_004736
XPR1

xenotropic and polytropic retrovirus receptor 1

chr11_+_58939539 0.587 NM_015177
DTX4
deltex homolog 4 (Drosophila)
chr6_+_80340971 0.585 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr5_-_121414011 0.578 NM_002317
LOX
lysyl oxidase
chr12_+_32112286 0.578 NM_018169
C12orf35
chromosome 12 open reading frame 35
chr12_+_110152186 0.577 NM_032829
C12orf34
chromosome 12 open reading frame 34
chr6_-_119399759 0.576 NM_024581
FAM184A
family with sequence similarity 184, member A
chr16_+_69599868 0.575 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr14_+_105266878 0.572 NM_001137601
ZBTB42
zinc finger and BTB domain containing 42
chr15_-_77712436 0.572 NM_024776
PEAK1
NKF3 kinase family member
chr16_+_77822400 0.571 NM_020927
VAT1L
vesicle amine transport protein 1 homolog (T. californica)-like
chrX_-_25034064 0.571 NM_139058
ARX
aristaless related homeobox
chr13_+_113623496 0.570 NM_001112732
MCF2L
MCF.2 cell line derived transforming sequence-like
chr22_+_46067677 0.569 NM_001167621
NM_013236
ATXN10

ataxin 10

chr13_+_113656027 0.562 NM_024979
MCF2L
MCF.2 cell line derived transforming sequence-like
chr14_+_103243813 0.562 NM_001199427
NM_003300
NM_145725
NM_145726
TRAF3



TNF receptor-associated factor 3



chr19_-_47734215 0.556 NM_014417
BBC3
BCL2 binding component 3
chr6_+_126240369 0.555 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr1_+_61547388 0.554 NM_001145512
NFIA
nuclear factor I/A
chr19_+_19322763 0.550 NM_004386
NCAN
neurocan
chrX_-_3631654 0.550 NM_005044
PRKX
protein kinase, X-linked
chr17_+_38296506 0.548 NM_007359
CASC3
cancer susceptibility candidate 3
chr7_+_114055048 0.545 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr9_-_140196702 0.527 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr1_-_57045235 0.526 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr9_-_100395961 0.522 NM_139246
TSTD2
thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr14_-_92414004 0.520 NM_006329
FBLN5
fibulin 5
chr2_+_7057471 0.514 NM_014746
RNF144A
ring finger protein 144A
chr15_-_65067696 0.512 NM_194272
RBPMS2
RNA binding protein with multiple splicing 2
chr6_+_126102278 0.512 NM_001199619
NM_001199620
NCOA7

nuclear receptor coactivator 7

chr19_+_38397841 0.509 NM_015073
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr9_+_34958171 0.508 NM_015297
KIAA1045
KIAA1045
chr5_-_133304274 0.499 NM_020199
C5orf15
chromosome 5 open reading frame 15
chr12_+_113495661 0.499 NM_004416
DTX1
deltex homolog 1 (Drosophila)
chr11_+_120110902 0.499 NM_014352
POU2F3
POU class 2 homeobox 3
chr12_-_88974094 0.498 NM_000899
NM_003994
KITLG

KIT ligand

chr2_+_242641310 0.473 NM_032329
ING5
inhibitor of growth family, member 5
chr1_-_166944504 0.473 NM_199351
ILDR2
immunoglobulin-like domain containing receptor 2
chr1_+_38261079 0.473 NM_152496
MANEAL
mannosidase, endo-alpha-like
chr4_+_26862312 0.472 NM_001169117
NM_001169118
NM_020860
STIM2


stromal interaction molecule 2


chr1_-_85930733 0.471 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr7_+_30174343 0.466 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr16_-_53737713 0.466 NM_001127897
NM_015272
RPGRIP1L

RPGRIP1-like

chr14_+_92788924 0.463 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr15_-_49255640 0.463 NM_203349
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr17_-_47439326 0.462 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr1_+_38259458 0.461 NM_001031740
NM_001113482
MANEAL

mannosidase, endo-alpha-like

chr4_-_16228097 0.460 NM_153365
TAPT1
transmembrane anterior posterior transformation 1
chr15_+_41221530 0.458 NM_019074
DLL4
delta-like 4 (Drosophila)
chr3_+_23987514 0.455 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr7_-_103629962 0.455 NM_005045
NM_173054
RELN

reelin

chr6_-_119470336 0.452 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr9_+_127019782 0.451 NM_001166167
NM_001145001
NM_014397
NEK6


NIMA (never in mitosis gene a)-related kinase 6


chr17_-_47492216 0.450 NM_002634
PHB
prohibitin
chr17_-_73775822 0.449 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr5_-_38595506 0.448 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr3_-_155394104 0.445 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chr19_-_2721337 0.444 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr9_-_99382073 0.443 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr9_+_127020462 0.442 NM_001166168
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr17_-_71088832 0.436 NM_001159770
NM_139177
SLC39A11

solute carrier family 39 (metal ion transporter), member 11

chr22_-_17602142 0.436 NM_031890
NM_001163079
CECR6

cat eye syndrome chromosome region, candidate 6

chr10_+_70320044 0.435 NM_030625
TET1
tet methylcytosine dioxygenase 1
chr3_+_11034419 0.434 NM_003042
SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr7_+_6144504 0.434 NM_032172
USP42
ubiquitin specific peptidase 42
chr9_-_112260529 0.433 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr20_+_10199455 0.432 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chrX_+_68725077 0.430 NM_015686
FAM155B
family with sequence similarity 155, member B
chr7_+_116312412 0.427 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr11_+_121322848 0.424 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr3_+_23986735 0.424 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr5_-_38556682 0.423 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr3_+_14444083 0.422 NM_001134367
NM_001134368
NM_003043
SLC6A6


solute carrier family 6 (neurotransmitter transporter, taurine), member 6


chr1_-_86043932 0.419 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr6_+_148663728 0.418 NM_015278
SASH1
SAM and SH3 domain containing 1
chr6_+_1312674 0.417 NM_033260
FOXQ1
forkhead box Q1
chr1_-_1535446 0.416 NM_001242659
LOC643988
uncharacterized LOC643988
chr1_+_211433285 0.416 NM_018254
RCOR3
REST corepressor 3
chr19_+_55795533 0.413 NM_032430
BRSK1
BR serine/threonine kinase 1
chr5_-_179780314 0.411 NM_005110
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr3_+_119187782 0.409 NM_152305
POGLUT1
protein O-glucosyltransferase 1
chr19_-_47735858 0.405 NM_001127240
NM_001127241
NM_001127242
BBC3


BCL2 binding component 3


chr6_+_149068148 0.401 NM_005715
UST
uronyl-2-sulfotransferase
chr22_+_51113069 0.400 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr1_+_203274646 0.400 NM_006763
BTG2
BTG family, member 2
chr5_-_124080773 0.395 NM_020747
ZNF608
zinc finger protein 608
chr11_-_123525300 0.394 NM_001040151
NM_018400
SCN3B

sodium channel, voltage-gated, type III, beta

chr15_-_61521478 0.392 NM_134261
RORA
RAR-related orphan receptor A
chr9_-_99329092 0.390 NM_001077181
CDC14B
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr15_-_37392358 0.388 NM_170674
NM_170675
NM_170676
NM_170677
MEIS2



Meis homeobox 2



chr16_-_73082169 0.387 NM_006885
ZFHX3
zinc finger homeobox 3
chr13_-_41240607 0.386 NM_002015
FOXO1
forkhead box O1
chr11_+_14665268 0.386 NM_000922
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr4_+_81952118 0.384 NM_001201
BMP3
bone morphogenetic protein 3
chr15_+_91447419 0.384 NM_006122
MAN2A2
mannosidase, alpha, class 2A, member 2
chr12_+_54943176 0.380 NM_000924
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr12_+_54955226 0.380 NM_001165975
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr3_-_141868208 0.373 NM_001178138
NM_001178139
TFDP2

transcription factor Dp-2 (E2F dimerization partner 2)

chr10_-_52383611 0.372 NM_147156
SGMS1
sphingomyelin synthase 1
chr1_-_51787881 0.371 NM_001080494
TTC39A
tetratricopeptide repeat domain 39A
chr6_-_37665631 0.368 NM_153487
MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr3_+_139654001 0.365 NM_022131
CLSTN2
calsyntenin 2
chr1_+_101361589 0.363 NM_001144884
NM_133496
SLC30A7

solute carrier family 30 (zinc transporter), member 7

chr9_+_127054246 0.360 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr3_-_155421996 0.360 NM_014996
PLCH1
phospholipase C, eta 1
chr11_-_8985955 0.360 NM_020644
TMEM9B
TMEM9 domain family, member B
chr10_-_21186530 0.359 NM_006393
NEBL
nebulette
chr16_+_2587951 0.357 NM_002613
NM_031268
PDPK1

3-phosphoinositide dependent protein kinase-1

chr8_+_28351694 0.357 NM_017412
NM_145866
FZD3

frizzled family receptor 3

chrX_+_64708614 0.356 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chr7_-_152133071 0.354 NM_170606
MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chrX_+_105066531 0.353 NM_198465
NRK
Nik related kinase
chr4_+_6784453 0.353 NM_001100590
NM_014743
KIAA0232

KIAA0232

chr6_-_107435635 0.353 NM_001080450
BEND3
BEN domain containing 3
chr2_-_85555343 0.351 NM_001206840
NM_001206841
NM_001206844
NM_006464
TGOLN2



trans-golgi network protein 2



chr11_-_74109417 0.350 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chr4_+_5053464 0.349 NM_018401
STK32B
serine/threonine kinase 32B
chr8_-_23540401 0.349 NM_006167
NKX3-1
NK3 homeobox 1
chr10_-_71930185 0.345 NM_001142648
NM_020150
SAR1A

SAR1 homolog A (S. cerevisiae)

chr18_+_49866541 0.340 NM_005215
DCC
deleted in colorectal carcinoma
chr1_+_27561006 0.338 NM_015023
WDTC1
WD and tetratricopeptide repeats 1
chr8_-_103424897 0.335 NM_015902
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr16_+_66878281 0.333 NM_005182
CA7
carbonic anhydrase VII
chr20_+_2673193 0.332 NM_001110514
EBF4
early B-cell factor 4
chr14_-_53620032 0.332 NM_001160147
NM_001160148
NM_030637
DDHD1


DDHD domain containing 1


chr20_-_48530275 0.330 NM_001135773
SPATA2
spermatogenesis associated 2
chr2_-_100721792 0.329 NM_001025108
AFF3
AF4/FMR2 family, member 3
chr4_+_85504056 0.327 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr14_+_77564570 0.327 NM_033426
KIAA1737
KIAA1737
chr1_-_184006828 0.324 NM_015101
GLT25D2
glycosyltransferase 25 domain containing 2
chr14_-_78083109 0.323 NM_004863
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr7_-_139876718 0.321 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr17_-_7232455 0.320 NM_001005408
NM_032442
NEURL4

neuralized homolog 4 (Drosophila)

chr16_-_12010518 0.315 NM_001130007
GSPT1
G1 to S phase transition 1
chr10_+_104503724 0.314 NM_001083913
C10orf26
chromosome 10 open reading frame 26
chr1_+_211432693 0.313 NM_001136223
NM_001136224
NM_001136225
RCOR3


REST corepressor 3


chr5_-_115910406 0.312 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.64 2.71e-08 GO:0007275 multicellular organismal development
1.57 3.06e-07 GO:0032502 developmental process
1.67 1.01e-06 GO:0048731 system development
3.35 1.28e-06 GO:0007389 pattern specification process
1.98 2.21e-06 GO:0007399 nervous system development
2.23 3.52e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.70 7.07e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.58 8.19e-06 GO:0048856 anatomical structure development
2.55 1.12e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.91 1.70e-05 GO:0009653 anatomical structure morphogenesis
1.72 1.71e-05 GO:0006355 regulation of transcription, DNA-dependent
1.65 3.25e-05 GO:0010556 regulation of macromolecule biosynthetic process
2.43 3.51e-05 GO:0051254 positive regulation of RNA metabolic process
1.69 3.54e-05 GO:0051252 regulation of RNA metabolic process
2.32 3.67e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.41 4.75e-05 GO:0010628 positive regulation of gene expression
1.63 4.94e-05 GO:0010468 regulation of gene expression
2.32 5.43e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
1.71 6.62e-05 GO:0048869 cellular developmental process
1.30 8.79e-05 GO:0050794 regulation of cellular process
1.60 9.24e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.26 9.68e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
2.68 1.05e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.70 1.22e-04 GO:0030154 cell differentiation
2.18 1.28e-04 GO:0048699 generation of neurons
1.58 3.04e-04 GO:0031326 regulation of cellular biosynthetic process
2.83 3.59e-04 GO:0048598 embryonic morphogenesis
2.09 3.65e-04 GO:0022008 neurogenesis
2.66 4.09e-04 GO:0032583 regulation of gene-specific transcription
1.55 4.92e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.56 5.58e-04 GO:0009889 regulation of biosynthetic process
2.23 7.89e-04 GO:0030182 neuron differentiation
2.78 8.28e-04 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
2.10 8.40e-04 GO:0031328 positive regulation of cellular biosynthetic process
2.03 1.10e-03 GO:0048468 cell development
1.26 1.19e-03 GO:0050789 regulation of biological process
2.07 1.40e-03 GO:0009891 positive regulation of biosynthetic process
2.34 1.47e-03 GO:0048666 neuron development
1.57 1.62e-03 GO:0048522 positive regulation of cellular process
3.01 1.80e-03 GO:0035295 tube development
1.53 1.87e-03 GO:0048518 positive regulation of biological process
2.29 1.92e-03 GO:0010629 negative regulation of gene expression
1.87 1.99e-03 GO:0031325 positive regulation of cellular metabolic process
2.44 2.23e-03 GO:0031175 neuron projection development
1.44 2.67e-03 GO:0031323 regulation of cellular metabolic process
1.24 2.70e-03 GO:0065007 biological regulation
2.33 3.18e-03 GO:0051253 negative regulation of RNA metabolic process
1.44 3.22e-03 GO:0080090 regulation of primary metabolic process
1.86 3.30e-03 GO:0010604 positive regulation of macromolecule metabolic process
2.15 4.14e-03 GO:0009790 embryo development
1.98 4.24e-03 GO:0010605 negative regulation of macromolecule metabolic process
2.21 4.49e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.31 5.14e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.79 6.64e-03 GO:0009893 positive regulation of metabolic process
2.39 6.90e-03 GO:0072358 cardiovascular system development
2.39 6.90e-03 GO:0072359 circulatory system development
2.17 7.48e-03 GO:0030030 cell projection organization
2.60 7.62e-03 GO:0016568 chromatin modification
2.93 7.74e-03 GO:0045596 negative regulation of cell differentiation
2.20 9.19e-03 GO:0000902 cell morphogenesis
2.11 1.33e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
3.34 1.37e-02 GO:0016570 histone modification
2.08 1.53e-02 GO:0031327 negative regulation of cellular biosynthetic process
2.14 1.65e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37 1.72e-02 GO:0019222 regulation of metabolic process
3.28 1.76e-02 GO:0016569 covalent chromatin modification
1.86 1.80e-02 GO:0009892 negative regulation of metabolic process
2.27 1.96e-02 GO:0000904 cell morphogenesis involved in differentiation
1.58 2.15e-02 GO:0048513 organ development
2.12 2.20e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.41 2.22e-02 GO:0060255 regulation of macromolecule metabolic process
2.04 2.51e-02 GO:0009890 negative regulation of biosynthetic process
1.38 2.94e-02 GO:0023052 signaling
2.09 3.01e-02 GO:0032989 cellular component morphogenesis
1.88 3.04e-02 GO:0031324 negative regulation of cellular metabolic process
2.40 3.38e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.35 3.57e-02 GO:0007409 axonogenesis
2.30 3.73e-02 GO:0048812 neuron projection morphogenesis
2.25 4.20e-02 GO:0006325 chromatin organization
1.89 4.27e-02 GO:0009888 tissue development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.69 1.11e-02 GO:0005667 transcription factor complex
1.26 1.42e-02 GO:0005634 nucleus
2.25 1.70e-02 GO:0045202 synapse
1.84 4.70e-02 GO:0044451 nucleoplasm part
4.99 4.76e-02 GO:0044309 neuron spine

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.36 4.14e-09 GO:0030528 transcription regulator activity
2.11 6.71e-06 GO:0001071 nucleic acid binding transcription factor activity
2.11 6.71e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
2.38 8.47e-06 GO:0043565 sequence-specific DNA binding
2.94 1.01e-04 GO:0016563 transcription activator activity
2.43 1.10e-03 GO:0019904 protein domain specific binding
2.73 2.57e-03 GO:0008134 transcription factor binding
2.79 6.39e-03 GO:0003702 RNA polymerase II transcription factor activity
2.49 1.68e-02 GO:0016564 transcription repressor activity
1.45 3.45e-02 GO:0003677 DNA binding
2.78 3.87e-02 GO:0000975 regulatory region DNA binding
2.78 3.87e-02 GO:0001067 regulatory region nucleic acid binding
2.78 3.87e-02 GO:0044212 transcription regulatory region DNA binding