Motif ID: CTCF.p2

Z-value: 1.180


Transcription factors associated with CTCF.p2:

Gene SymbolEntrez IDGene Name
CTCF 10664 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CTCFchr16_+_67596309-0.402.8e-02Click!


Activity profile for motif CTCF.p2.

activity profile for motif CTCF.p2


Sorted Z-values histogram for motif CTCF.p2

Sorted Z-values for motif CTCF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CTCF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_45722762 7.816 NM_032413
NM_197955
C15orf48

chromosome 15 open reading frame 48

chr5_-_136834887 4.809 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr22_+_31478845 4.561 NM_001207017
SMTN
smoothelin
chr8_+_54764367 4.180 NM_170587
RGS20
regulator of G-protein signaling 20
chr7_+_40174594 3.771 C7orf10
chromosome 7 open reading frame 10
chr9_+_131182690 3.745 NM_016174
CERCAM
cerebral endothelial cell adhesion molecule
chr19_-_19052032 3.548 NM_004838
HOMER3
homer homolog 3 (Drosophila)
chr19_-_19051899 3.536 HOMER3
homer homolog 3 (Drosophila)
chr5_-_139726173 3.461 NM_001945
HBEGF
heparin-binding EGF-like growth factor
chr9_+_131183122 3.406 CERCAM
cerebral endothelial cell adhesion molecule
chr14_-_75078669 3.207 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr1_+_212208918 3.182 NM_016448
DTL
denticleless homolog (Drosophila)
chr5_+_148520985 3.126 NM_014945
ABLIM3
actin binding LIM protein family, member 3
chr12_-_25101993 3.078 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr11_+_118827007 2.975 NM_006760
UPK2
uroplakin 2
chr3_-_196756572 2.716 MFI2
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr7_+_40174480 2.678 NM_001193311
NM_001193312
NM_001193313
NM_024728
C7orf10



chromosome 7 open reading frame 10



chr19_-_41859830 2.667 NM_000660
TGFB1
transforming growth factor, beta 1
chr10_-_76995685 2.635 NM_144589
COMTD1
catechol-O-methyltransferase domain containing 1
chr20_+_37554954 2.589 NM_030919
FAM83D
family with sequence similarity 83, member D
chr4_+_154265841 2.529 MND1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr4_+_154265774 2.480 NM_001253861
NM_032117
MND1

meiotic nuclear divisions 1 homolog (S. cerevisiae)

chr1_+_37940180 2.426 ZC3H12A
zinc finger CCCH-type containing 12A
chr18_-_21166440 2.388 NM_000271
NPC1
Niemann-Pick disease, type C1
chr12_-_25101923 2.377 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr1_+_37940129 2.369 ZC3H12A
zinc finger CCCH-type containing 12A
chr3_-_196756682 2.361 NM_033316
NM_005929
MFI2

antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5

chr19_+_48216600 2.257 NM_014601
EHD2
EH-domain containing 2
chr6_+_151186884 2.231 MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr17_-_43209681 2.173 NM_133373
PLCD3
phospholipase C, delta 3
chr6_+_151187064 2.135 MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr6_+_151186814 2.062 NM_001242767
NM_001242769
NM_015440
MTHFD1L


methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like


chr19_-_4400470 2.035 NM_001199943
NM_003025
SH3GL1

SH3-domain GRB2-like 1

chr15_+_81071708 2.002 NM_018689
KIAA1199
KIAA1199
chr1_+_37940074 1.986 NM_025079
ZC3H12A
zinc finger CCCH-type containing 12A
chr3_+_172468469 1.958 ECT2
epithelial cell transforming sequence 2 oncogene
chr17_-_34122547 1.951 NM_001032278
NM_024302
MMP28

matrix metallopeptidase 28

chr17_+_1958354 1.938 NM_006497
HIC1
hypermethylated in cancer 1
chr17_-_76183074 1.922 NM_003258
TK1
thymidine kinase 1, soluble
chr1_+_193091283 1.822 CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr16_+_31484497 1.780 NM_015927
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr1_+_212209112 1.736 DTL
denticleless homolog (Drosophila)
chr19_-_36001336 1.733 NM_001126059
DMKN
dermokine
chr16_-_90085786 1.625 NM_001042610
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr6_-_131384321 1.619 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr20_-_1294111 1.592 NM_015685
SDCBP2
syndecan binding protein (syntenin) 2
chr12_+_107712151 1.576 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chr1_+_10270680 1.527 NM_015074
NM_183416
KIF1B

kinesin family member 1B

chr11_+_60691911 1.515 NM_017870
NM_178031
TMEM132A

transmembrane protein 132A

chr6_+_33359312 1.482 NM_002263
KIFC1
kinesin family member C1
chrX_+_152110214 1.411 NM_001178115
ZNF185
zinc finger protein 185 (LIM domain)
chr5_-_125930604 1.396 NM_001182
NM_001201377
NM_001202404
ALDH7A1


aldehyde dehydrogenase 7 family, member A1


chr16_+_71392637 1.394 CALB2
calbindin 2
chr14_+_23305816 1.393 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr16_+_71392615 1.347 NM_001740
NM_007088
CALB2

calbindin 2

chr15_-_40212425 1.346 GPR176
G protein-coupled receptor 176
chr12_+_49208615 1.338 CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr10_-_30024594 1.327 NM_003174
SVIL
supervillin
chr19_-_15590203 1.310 NM_052890
PGLYRP2
peptidoglycan recognition protein 2
chr2_+_228336809 1.295 AGFG1
ArfGAP with FG repeats 1
chr12_+_120105656 1.292 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr11_+_44117258 1.290 EXT2
exostosin 2
chr14_+_23305907 1.288 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr14_+_52118539 1.283 NM_152330
FRMD6
FERM domain containing 6
chr11_-_18127584 1.283 NM_138421
SAAL1
serum amyloid A-like 1
chr19_-_4400357 1.261 NM_001199944
SH3GL1
SH3-domain GRB2-like 1
chr14_-_107083398 1.248 IGH@
IGHA1
IGHG1
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_-_18507151 1.244 NM_001122731
NM_001136004
NM_015241
MICAL3


microtubule associated monoxygenase, calponin and LIM domain containing 3


chr19_-_19754369 1.235 GMIP
GEM interacting protein
chr3_+_50192420 1.232 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_49208979 1.220 NM_173546
KLHDC8B
kelch domain containing 8B
chr10_+_13203547 1.172 NM_018518
NM_182751
MCM10

minichromosome maintenance complex component 10

chr7_-_92747317 1.169 NM_001193307
NM_017654
SAMD9

sterile alpha motif domain containing 9

chr2_-_219157207 1.157 NM_022152
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr16_+_15737123 1.154 NM_001143979
NDE1
nudE nuclear distribution gene E homolog 1 (A. nidulans)
chr20_+_30102313 1.149 HM13
histocompatibility (minor) 13
chr14_+_23305913 1.132 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr5_-_76788017 1.120 WDR41
WD repeat domain 41
chr6_+_35310399 1.120 PPARD
peroxisome proliferator-activated receptor delta
chr17_-_72357957 1.117 NM_001080466
BTBD17
BTB (POZ) domain containing 17
chr1_-_85514174 1.110 NM_001253693
NM_018298
MCOLN3

mucolipin 3

chr5_-_76788140 1.109 WDR41
WD repeat domain 41
chr19_-_19754452 1.108 NM_016573
GMIP
GEM interacting protein
chr5_-_76788240 1.092 NM_018268
WDR41
WD repeat domain 41
chr9_+_116917716 1.085 COL27A1
collagen, type XXVII, alpha 1
chr19_+_38826442 1.075 NM_021185
CATSPERG
cation channel, sperm-associated, gamma
chr6_+_35310336 1.067 PPARD
peroxisome proliferator-activated receptor delta
chr10_+_99332197 1.066 NM_001129981
NM_020349
ANKRD2

ankyrin repeat domain 2 (stretch responsive muscle)

chr9_+_103189494 1.066 NM_001198807
NM_080655
NM_001198805
C9orf30


chromosome 9 open reading frame 30


chr20_+_44441671 1.060 NM_181801
UBE2C
ubiquitin-conjugating enzyme E2C
chr15_+_74165967 1.058 NM_153356
TBC1D21
TBC1 domain family, member 21
chr16_-_90086299 1.046 DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr2_+_228678556 1.045 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr10_+_112257624 1.032 NM_004419
DUSP5
dual specificity phosphatase 5
chr19_+_39903749 1.016 NM_022835
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr12_-_120703488 1.009 PXN
paxillin
chr20_-_46415277 0.996 NM_001161841
NM_198596
SULF2

sulfatase 2

chr22_-_22307212 0.993 NM_014634
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr11_+_44117098 0.987 NM_001178083
NM_207122
EXT2

exostosin 2

chr1_-_159915382 0.983 NM_001135050
NM_020789
IGSF9

immunoglobulin superfamily, member 9

chr7_-_22539795 0.983 NM_001164460
NM_207342
STEAP1B

STEAP family member 1B

chr13_-_101241007 0.975 NM_001195087
A2LD1
AIG2-like domain 1
chr16_+_16326454 0.974 NOMO2
NODAL modulator 2
chr6_+_35310317 0.969 NM_001171818
NM_001171819
NM_001171820
NM_006238
NM_177435
PPARD




peroxisome proliferator-activated receptor delta




chr10_-_92617417 0.957 HTR7
5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
chr8_+_42948648 0.956 NM_032237
SGK196
protein kinase-like protein SgK196
chr7_+_89783789 0.955 STEAP1
six transmembrane epithelial antigen of the prostate 1
chr16_+_16326488 0.946 NOMO2
NODAL modulator 2
chr16_-_47177832 0.938 NETO2
neuropilin (NRP) and tolloid (TLL)-like 2
chr19_+_54926604 0.933 NM_001005367
NM_001201461
NM_020659
TTYH1


tweety homolog 1 (Drosophila)


chr9_-_38069082 0.926 SHB
Src homology 2 domain containing adaptor protein B
chr12_-_120703549 0.921 NM_001080855
NM_001243756
NM_002859
PXN


paxillin


chr15_-_41624760 0.918 NM_007280
OIP5
Opa interacting protein 5
chr19_-_2051222 0.914 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr17_-_48474910 0.904 NM_018509
LRRC59
leucine rich repeat containing 59
chr20_+_30102237 0.899 NM_030789
NM_178580
NM_178581
NM_178582
HM13



histocompatibility (minor) 13



chr14_-_91282760 0.896 NM_001010854
TTC7B
tetratricopeptide repeat domain 7B
chr11_-_117102810 0.893 NM_004716
PCSK7
proprotein convertase subtilisin/kexin type 7
chr5_-_146833150 0.886 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr11_-_117102758 0.885 PCSK7
proprotein convertase subtilisin/kexin type 7
chr17_+_43213013 0.885 NM_001135705
NM_001135706
NM_001135707
NM_024722
ACBD4



acyl-CoA binding domain containing 4



chr14_+_23305792 0.876 NM_004995
MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr15_-_38856830 0.875 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr11_+_9779832 0.874 LOC283104
uncharacterized LOC283104
chr16_-_69788798 0.870 NM_014062
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr19_-_1650246 0.869 NM_001136139
TCF3
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
chr11_+_119076974 0.858 NM_005188
CBL
Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr4_-_41216455 0.856 NM_001166050
NM_004307
NM_173075
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr1_-_10003321 0.855 LZIC
leucine zipper and CTNNBIP1 domain containing
chr18_+_60382617 0.855 NM_194449
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
chr1_+_24645811 0.854 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr11_+_64018996 0.853 PLCB3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr19_-_49496369 0.848 GYS1
glycogen synthase 1 (muscle)
chr16_-_47177902 0.846 NM_001201477
NM_018092
NETO2

neuropilin (NRP) and tolloid (TLL)-like 2

chr12_+_49208214 0.841 NM_001206917
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr19_-_49496520 0.840 GYS1
glycogen synthase 1 (muscle)
chr7_-_14030864 0.840 NM_001163149
ETV1
ets variant 1
chr19_-_49496566 0.836 NM_001161587
NM_002103
GYS1

glycogen synthase 1 (muscle)

chr7_+_89783688 0.834 NM_012449
STEAP1
six transmembrane epithelial antigen of the prostate 1
chr16_+_16326507 0.832


chr2_+_228336877 0.831 NM_001135187
NM_001135188
NM_001135189
NM_004504
AGFG1



ArfGAP with FG repeats 1



chr2_-_232395108 0.829 NM_006056
NMUR1
neuromedin U receptor 1
chr17_-_48474678 0.815 LRRC59
leucine rich repeat containing 59
chr18_-_47340208 0.815 NM_006111
ACAA2
acetyl-CoA acyltransferase 2
chr1_-_10002825 0.808 NM_032368
LZIC
leucine zipper and CTNNBIP1 domain containing
chr6_+_159590428 0.800 NM_032532
FNDC1
fibronectin type III domain containing 1
chr6_+_34482646 0.796 NM_001199583
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr9_-_140317650 0.795 EXD3
exonuclease 3'-5' domain containing 3
chr1_-_32281577 0.793 NM_144569
SPOCD1
SPOC domain containing 1
chr15_+_63340314 0.793 NM_001018008
TPM1
tropomyosin 1 (alpha)
chr11_+_64018991 0.781 NM_000932
NM_001184883
PLCB3

phospholipase C, beta 3 (phosphatidylinositol-specific)

chr19_-_1848447 0.780 NM_020695
REXO1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr19_+_56165415 0.771 NM_001012478
NM_007279
U2AF2

U2 small nuclear RNA auxiliary factor 2

chr5_+_157170702 0.769 NM_173491
LSM11
LSM11, U7 small nuclear RNA associated
chr1_-_93426998 0.766 NM_001006605
NM_001252269
NM_001252270
NM_001252273
FAM69A



family with sequence similarity 69, member A



chr10_+_102759232 0.765 LZTS2
leucine zipper, putative tumor suppressor 2
chr2_-_132249946 0.756 MZT2A
mitotic spindle organizing protein 2A
chr17_-_45908876 0.756 NM_145255
NM_148887
MRPL10

mitochondrial ribosomal protein L10

chr17_+_72199794 0.754 NM_000999
NM_001035258
RPL38

ribosomal protein L38

chr2_-_24307179 0.753 NM_001206802
TP53I3
tumor protein p53 inducible protein 3
chr22_-_22307188 0.750 PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr17_+_45810609 0.747 NM_013351
TBX21
T-box 21
chr7_-_92747269 0.739 SAMD9
sterile alpha motif domain containing 9
chr17_-_33469269 0.735 NM_001014445
NM_018096
NLE1

notchless homolog 1 (Drosophila)

chr3_-_186857188 0.734 NM_052969
RPL39L
ribosomal protein L39-like
chr12_-_25102281 0.732 NM_001178091
NM_001178092
NM_005504
BCAT1


branched chain amino-acid transaminase 1, cytosolic


chr11_-_66360485 0.730 NM_018219
CCDC87
coiled-coil domain containing 87
chr11_+_85566143 0.727 NM_173556
CCDC83
coiled-coil domain containing 83
chr11_-_66206260 0.726 NM_016050
NM_170738
NM_170739
MRPL11


mitochondrial ribosomal protein L11


chr2_-_120282060 0.724 SCTR
secretin receptor
chr1_+_154377668 0.723 NM_000565
NM_001206866
NM_181359
IL6R


interleukin 6 receptor


chr17_+_72199841 0.719 RPL38
ribosomal protein L38
chr12_+_50898744 0.711 NM_173602
DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr5_+_54455945 0.703 NM_001008397
GPX8
glutathione peroxidase 8 (putative)
chr16_-_67360625 0.701 NM_001100915
KCTD19
potassium channel tetramerisation domain containing 19
chr7_-_100425035 0.687 NM_004444
EPHB4
EPH receptor B4
chr3_+_58291954 0.686 NM_001098783
NM_007042
RPP14

ribonuclease P/MRP 14kDa subunit

chr11_+_925899 0.684 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr14_+_105155724 0.681 NM_001031714
NM_022489
NM_032714
INF2


inverted formin, FH2 and WH2 domain containing


chr19_+_1941184 0.676 CSNK1G2
casein kinase 1, gamma 2
chr6_-_139309339 0.673 REPS1
RALBP1 associated Eps domain containing 1
chr14_-_65289812 0.672 NM_000347
NM_001024858
SPTB

spectrin, beta, erythrocytic

chr19_-_14224979 0.668 NM_207518
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr14_-_107211131 0.664 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_-_113498615 0.663 NM_001166496
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr1_-_211307314 0.661 NM_002238
NM_172362
KCNH1

potassium voltage-gated channel, subfamily H (eag-related), member 1

chr5_-_140998567 0.660 NM_001079812
NM_005219
DIAPH1

diaphanous homolog 1 (Drosophila)

chr20_+_30028410 0.659 NM_153324
DEFB123
defensin, beta 123
chr19_+_45349560 0.657 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr2_-_120282012 0.656 NM_002980
SCTR
secretin receptor
chr11_+_925874 0.653 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr14_-_106877689 0.653 IGHV4-31
IGH@
IGHA1
IGHA2
IGHG1
IGHG4
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 4 (G4m marker)
immunoglobulin heavy constant mu
chr8_+_41386765 0.650 GINS4
GINS complex subunit 4 (Sld5 homolog)
chr16_+_16326478 0.649 NOMO2
NODAL modulator 2
chr6_-_139309391 0.643 NM_001128617
NM_031922
REPS1

RALBP1 associated Eps domain containing 1

chr19_+_54926721 0.636 TTYH1
tweety homolog 1 (Drosophila)
chr5_-_179636124 0.633 NM_175062
RASGEF1C
RasGEF domain family, member 1C
chr19_-_1848359 0.631 REXO1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr15_-_40630272 0.629 C15orf52
chromosome 15 open reading frame 52
chr7_+_28338939 0.626 NM_182899
CREB5
cAMP responsive element binding protein 5

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 1.07e-04 GO:0005737 cytoplasm
1.53 9.14e-04 GO:0005829 cytosol
1.26 1.33e-03 GO:0044444 cytoplasmic part
4.74 4.98e-03 GO:0015934 large ribosomal subunit
5.68 1.83e-02 GO:0022625 cytosolic large ribosomal subunit

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.21 3.21e-03 GO:0005515 protein binding