Motif ID: CUX2.p2

Z-value: 0.318


Transcription factors associated with CUX2.p2:

Gene SymbolEntrez IDGene Name
CUX2 23316 cut-like homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CUX2chr12_+_1114718270.135.0e-01Click!


Activity profile for motif CUX2.p2.

activity profile for motif CUX2.p2


Sorted Z-values histogram for motif CUX2.p2

Sorted Z-values for motif CUX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CUX2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_131321868 0.542 NM_001252660
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr9_-_85946875 0.398 NM_001244961
FRMD3
FERM domain containing 3
chr3_+_159557649 0.367 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr2_-_192016293 0.353 NM_001243835
STAT4
signal transducer and activator of transcription 4
chr3_+_159557745 0.349 SCHIP1
schwannomin interacting protein 1
chr13_-_46756291 0.342 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_-_58864820 0.296 NM_130786
A1BG
alpha-1-B glycoprotein
chr13_+_53035227 0.256 CKAP2
cytoskeleton associated protein 2
chr12_-_54653317 0.235 NM_001127322
CBX5
chromobox homolog 5
chr12_-_54653369 0.226 NM_001127321
CBX5
chromobox homolog 5
chr3_+_100238063 0.220 TMEM45A
transmembrane protein 45A
chr1_+_198608216 0.209 PTPRC
protein tyrosine phosphatase, receptor type, C
chr3_+_85775631 0.201 NM_153184
CADM2
cell adhesion molecule 2
chr4_+_15429628 0.191 NM_031911
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr4_-_47983430 0.187 NM_001142564
CNGA1
cyclic nucleotide gated channel alpha 1
chr2_+_132480063 0.183 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr7_-_36764000 0.148 NM_001177506
NM_001177507
NM_001637
AOAH


acyloxyacyl hydrolase (neutrophil)


chr16_+_30064470 0.147 ALDOA
aldolase A, fructose-bisphosphate
chr5_+_126984712 0.143 NM_001048252
CTXN3
cortexin 3
chr19_-_49243836 0.139 NM_017805
RASIP1
Ras interacting protein 1
chr1_+_198608136 0.133 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr17_-_79876024 0.131 SIRT7
sirtuin 7
chr1_+_57320442 0.129 NM_000562
C8A
complement component 8, alpha polypeptide
chr1_+_110993748 0.128 NM_032414
PROK1
prokineticin 1
chr7_-_100239136 0.127 NM_003227
TFR2
transferrin receptor 2
chr1_+_206730456 0.123 NM_182665
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr1_+_198608244 0.123 PTPRC
protein tyrosine phosphatase, receptor type, C
chr22_-_26961333 0.118 NM_001008566
TPST2
tyrosylprotein sulfotransferase 2
chr8_+_18248754 0.110 NM_000015
NAT2
N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr3_+_52811601 0.110 NM_002215
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr6_+_121756744 0.109 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr7_-_23509972 0.105 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr8_+_77593522 0.105 ZFHX4
zinc finger homeobox 4
chr14_-_74025643 0.105 NM_001220484
NM_203309
HEATR4

HEAT repeat containing 4

chr12_-_11422640 0.105 NM_006249
PRB3
proline-rich protein BstNI subfamily 3
chr9_-_5304579 0.100 NM_005059
NM_134441
RLN2

relaxin 2

chr12_-_10978867 0.099 NM_023921
TAS2R10
taste receptor, type 2, member 10
chr17_-_79876027 0.096 SIRT7
sirtuin 7
chr1_+_12976449 0.095 NM_001012276
PRAMEF8
PRAMEF7
PRAME family member 8
PRAME family member 7
chr7_-_144107319 0.095 NM_001080413
NOBOX
NOBOX oogenesis homeobox
chr1_-_17308072 0.095 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr17_-_8424217 0.093 MYH10
myosin, heavy chain 10, non-muscle
chr13_+_31309644 0.093 NM_001629
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr4_+_71587674 0.091 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr17_-_79875995 0.089 SIRT7
sirtuin 7
chr5_+_57787260 0.088 NM_152687
GAPT
GRB2-binding adaptor protein, transmembrane
chr20_-_1309809 0.087 NM_080489
SDCBP2
syndecan binding protein (syntenin) 2
chr6_+_131571298 0.085 NM_004842
NM_138633
AKAP7

A kinase (PRKA) anchor protein 7

chr9_+_96846710 0.085 NM_001253829
NM_152422
PTPDC1

protein tyrosine phosphatase domain containing 1

chr1_-_159684274 0.084 NM_000567
CRP
C-reactive protein, pentraxin-related
chr7_-_104909442 0.083 NM_182691
SRPK2
SRSF protein kinase 2
chr8_-_120651019 0.079 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr12_-_81763127 0.078 NM_001220479
NM_001220480
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr14_+_21457964 0.076 NM_001029991
NM_022734
METTL17

methyltransferase like 17

chrX_+_123480131 0.074 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chrX_-_107682600 0.073 NM_001847
COL4A6
collagen, type IV, alpha 6
chr5_+_88185090 0.071


chr4_+_187187117 0.071 NM_000128
F11
coagulation factor XI
chr17_-_64225496 0.070 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr17_+_67498391 0.070 MAP2K6
mitogen-activated protein kinase kinase 6
chr20_-_22566092 0.068 NM_153675
FOXA2
forkhead box A2
chr11_-_77734285 0.066 NM_023930
KCTD14
potassium channel tetramerisation domain containing 14
chrX_-_106362050 0.065 NM_001171080
NM_018301
RBM41

RNA binding motif protein 41

chr8_-_117023 0.065 NM_001005504
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr9_-_21228132 0.065 NM_021268
IFNA17
interferon, alpha 17
chr18_+_59157774 0.064 NM_031891
CDH20
cadherin 20, type 2
chr1_+_367639 0.064 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr3_-_126277757 0.061 NM_152533
C3orf22
chromosome 3 open reading frame 22
chr1_-_146068244 0.058 NM_001101663
NBPF11
NBPF24
neuroblastoma breakpoint family, member 11
neuroblastoma breakpoint family, member 24
chr17_-_46688362 0.058 NM_004502
HOXB7
homeobox B7
chr1_-_147610080 0.058 NM_001101663
NBPF11
NBPF24
neuroblastoma breakpoint family, member 11
neuroblastoma breakpoint family, member 24
chr5_+_180794268 0.054 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr17_+_56315786 0.054 NM_001160102
NM_006151
LPO

lactoperoxidase

chr20_-_17539480 0.054 NM_001161705
BFSP1
beaded filament structural protein 1, filensin
chr1_-_622033 0.053 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr14_+_88490893 0.051 LOC283587
uncharacterized LOC283587
chr5_-_58882274 0.051 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_-_15095791 0.050 NM_139167
SGCZ
sarcoglycan, zeta
chr17_-_46688279 0.049 HOXB7
homeobox B7
chr5_-_156390206 0.049 NM_001146726
NM_138379
TIMD4

T-cell immunoglobulin and mucin domain containing 4

chr2_-_172291227 0.049 NM_024770
METTL8
methyltransferase like 8
chr20_-_34241830 0.048 NM_003915
CPNE1
copine I
chr20_-_44298877 0.045 NM_147197
WFDC11
WAP four-disulfide core domain 11
chr8_-_17752847 0.044 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr4_-_70826712 0.043 NM_001891
CSN2
casein beta
chr1_-_151804225 0.043 NM_005060
RORC
RAR-related orphan receptor C
chrY_+_4924128 0.042 NM_032972
NM_032973
PCDH11X
PCDH11Y

protocadherin 11 X-linked
protocadherin 11 Y-linked

chr8_+_77593506 0.042 NM_024721
ZFHX4
zinc finger homeobox 4
chr11_+_117075682 0.042 TAGLN
transgelin
chr4_+_169418167 0.042 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr16_+_30064410 0.040 NM_000034
ALDOA
aldolase A, fructose-bisphosphate
chr4_-_2230957 0.039 NM_181808
POLN
polymerase (DNA directed) nu
chr3_+_46919235 0.037 NM_000316
PTH1R
parathyroid hormone 1 receptor
chr16_+_67381252 0.037 NM_001161575
LRRC36
leucine rich repeat containing 36
chr8_+_11188494 0.037 NM_054028
SLC35G5
solute carrier family 35, member G5
chr7_+_99425635 0.037 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr5_+_60933635 0.036 NM_173667
C5orf64
chromosome 5 open reading frame 64
chr16_+_12058963 0.035 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr12_+_6554032 0.034 NM_001242
CD27
CD27 molecule
chr2_-_89165652 0.034


chr6_-_32160637 0.034 GPSM3
G-protein signaling modulator 3
chr18_-_31628557 0.033 NM_001198549
NOL4
nucleolar protein 4
chr8_-_133459508 0.030 NM_001204824
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr3_+_134514044 0.030 NM_004441
EPHB1
EPH receptor B1
chr19_-_47287998 0.030 NM_001145145
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr18_-_70532933 0.030 NM_138999
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr5_-_147162056 0.029 JAKMIP2
janus kinase and microtubule interacting protein 2
chr4_-_82126200 0.029 NM_006259
PRKG2
protein kinase, cGMP-dependent, type II
chr14_-_74892804 0.027 NM_001105579
SYNDIG1L
synapse differentiation inducing 1-like
chr17_-_46687925 0.027 HOXB7
homeobox B7
chr5_-_140895407 0.025 DIAPH1
diaphanous homolog 1 (Drosophila)
chr11_+_92085261 0.024 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr14_-_20797532 0.024 NM_182852
NM_182851
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr14_+_29241989 0.024 C14orf23
chromosome 14 open reading frame 23
chr12_+_52056547 0.023 NM_001177984
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr18_-_64271215 0.022 NM_021153
CDH19
cadherin 19, type 2
chrX_+_106171328 0.022 CLDN2
claudin 2
chr15_-_59981433 0.022 BNIP2
BCL2/adenovirus E1B 19kDa interacting protein 2
chr11_+_57365026 0.022 NM_000062
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr17_-_2996289 0.021 NM_002548
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr2_-_178753464 0.021 NM_001077196
PDE11A
phosphodiesterase 11A
chr12_-_22089627 0.021 NM_005691
NM_020297
ABCC9

ATP-binding cassette, sub-family C (CFTR/MRP), member 9

chrX_+_91089658 0.021 NM_014522
NM_032968
NM_032969
PCDH11X


protocadherin 11 X-linked


chr1_-_149399159 0.020 NM_001024599
HIST2H2BF
histone cluster 2, H2bf
chr6_+_129204285 0.020 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr2_-_61245363 0.020 NM_144709
PUS10
pseudouridylate synthase 10
chr14_+_67831484 0.020 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr2_+_169926084 0.019 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr12_+_21168629 0.019 NM_001009562
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr3_-_42452022 0.019 NM_144634
LYZL4
lysozyme-like 4
chr12_+_26126687 0.018 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr4_+_71091787 0.018 NM_152997
C4orf7
chromosome 4 open reading frame 7
chr11_+_60145954 0.017 NM_021201
NM_206938
NM_206939
NM_206940
MS4A7



membrane-spanning 4-domains, subfamily A, member 7



chr11_+_55650772 0.017 NM_032681
SPRYD5
SPRY domain containing 5
chr12_+_131438451 0.017 NM_198827
GPR133
G protein-coupled receptor 133
chr22_-_40289793 0.017 NM_152512
ENTHD1
ENTH domain containing 1
chr2_-_77749335 0.017 NM_001134745
NM_024993
LRRTM4

leucine rich repeat transmembrane neuronal 4

chr12_+_125811161 0.017 NM_052907
TMEM132B
transmembrane protein 132B
chr4_-_47465719 0.016 COMMD8
COMM domain containing 8
chr6_-_68598987 0.016 ERVH-3
endogenous retrovirus group H, member 3
chr2_+_202004997 0.016 NM_001202515
CFLAR
CASP8 and FADD-like apoptosis regulator
chr13_-_41556360 0.015 NM_001145353
ELF1
E74-like factor 1 (ets domain transcription factor)
chr13_-_41556188 0.015 ELF1
E74-like factor 1 (ets domain transcription factor)
chr7_+_93535819 0.014 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr2_-_163008913 0.014 NM_002054
GCG
glucagon
chr12_-_118406027 0.013 NM_173598
KSR2
kinase suppressor of ras 2
chr4_+_71296208 0.012 NM_001145006
MUC7
mucin 7, secreted
chr12_+_14538232 0.012 ATF7IP
activating transcription factor 7 interacting protein
chr11_+_62037629 0.012 NM_002411
SCGB2A2
secretoglobin, family 2A, member 2
chrY_-_26194115 0.010 NM_001003894
NM_001003895
NM_004680
NM_170723
CDY1B

CDY1

chromodomain protein, Y-linked, 1B

chromodomain protein, Y-linked, 1

chr12_+_111471827 0.009 NM_015267
CUX2
cut-like homeobox 2
chr4_+_176987148 0.009 WDR17
WD repeat domain 17
chr17_-_33521376 0.009 NM_152462
SLC35G3
solute carrier family 35, member G3
chr16_-_75150617 0.009 LDHD
lactate dehydrogenase D
chr11_+_60146022 0.008 MS4A7
membrane-spanning 4-domains, subfamily A, member 7
chr2_-_152830448 0.008 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr4_+_166131170 0.008 NM_001161521
NM_001161522
KLHL2

kelch-like 2, Mayven (Drosophila)

chr1_+_111413820 0.007 NM_001040033
CD53
CD53 molecule
chr3_+_35721115 0.007 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chrX_-_118726852 0.007 NM_001173488
NKRF
NFKB repressing factor
chr10_+_69869249 0.006 NM_032578
MYPN
myopalladin
chr7_-_18067445 0.005 NM_175886
PRPS1L1
phosphoribosyl pyrophosphate synthetase 1-like 1
chr3_+_63428752 0.005 NM_144642
SYNPR
synaptoporin
chr15_+_38227456 0.004 NM_152453
TMCO5A
transmembrane and coiled-coil domains 5A
chr1_+_117297056 0.003 NM_001767
CD2
CD2 molecule
chr7_+_114066554 0.001 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr14_-_107199126 0.001 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr6_+_29426130 0.001 NM_030883
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr10_+_124151818 0.000 NM_021622
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr15_+_80364902 0.000 NM_001242915
NM_001242916
ZFAND6

zinc finger, AN1-type domain 6

chr1_-_186430216 0.000 NM_002597
PDC
phosducin

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.95 2.29e-02 GO:0005576 extracellular region

Nothing significant found in function category.