Motif ID: EBF1.p2

Z-value: 0.628


Transcription factors associated with EBF1.p2:

Gene SymbolEntrez IDGene Name
EBF1 1879 early B-cell factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EBF1chr5_-_1585266980.212.7e-01Click!


Activity profile for motif EBF1.p2.

activity profile for motif EBF1.p2


Sorted Z-values histogram for motif EBF1.p2

Sorted Z-values for motif EBF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_152240726 0.616 NM_001170944
NM_001242319
NM_032882
PNMA6C
PNMA6D
PNMA6A
paraneoplastic antigen like 6C
paraneoplastic antigen like 6D
paraneoplastic antigen like 6A
chr11_+_69924407 0.498 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr11_-_2019007 0.471 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr7_+_128578246 0.470 NM_032643
IRF5
interferon regulatory factor 5
chr7_+_128577990 0.449 NM_001098629
NM_001098630
NM_001242452
IRF5


interferon regulatory factor 5


chr17_+_4981754 0.423 ZFP3
zinc finger protein 3 homolog (mouse)
chr22_-_17747520 0.423 CECR3
cat eye syndrome chromosome region, candidate 3 (non-protein coding)
chr11_-_2019070 0.419 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr1_-_203154304 0.410 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr4_+_4388804 0.393 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr19_-_2308155 0.389 NM_001101391
LINGO3
leucine rich repeat and Ig domain containing 3
chr12_+_5153084 0.387 NM_002234
KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
chr8_-_144654921 0.365 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chr17_+_4981721 0.352 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chr6_+_42531767 0.329 UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr12_-_51717835 0.326 BIN2
bridging integrator 2
chr17_-_1928177 0.325 NM_178568
RTN4RL1
reticulon 4 receptor-like 1
chr1_+_8384389 0.325 NM_001080397
SLC45A1
solute carrier family 45, member 1
chr1_+_156339002 0.311 NM_020407
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr19_-_51845377 0.309 NM_001163922
VSIG10L
V-set and immunoglobulin domain containing 10 like
chr10_+_70587293 0.303 NM_001130159
NM_001130160
NM_001130161
NM_152709
STOX1



storkhead box 1



chr11_+_6260321 0.301 NM_001037329
CNGA4
cyclic nucleotide gated channel alpha 4
chr19_-_51487070 0.299 NM_139277
NM_001207053
NM_001243126
NM_005046
KLK7



kallikrein-related peptidase 7



chr1_-_27998719 0.296 NM_002038
NM_022872
NM_022873
IFI6


interferon, alpha-inducible protein 6


chr19_-_51456159 0.296 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr4_+_4388717 0.295 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr8_-_11324184 0.295 NM_053279
FAM167A
family with sequence similarity 167, member A
chr1_-_27998658 0.292 IFI6
interferon, alpha-inducible protein 6
chr4_+_4387982 0.278 NM_001040101
NM_014392
D4S234E

DNA segment on chromosome 4 (unique) 234 expressed sequence

chr17_-_10101854 0.275 NM_201433
GAS7
growth arrest-specific 7
chr13_+_113622758 0.275 MCF2L
MCF.2 cell line derived transforming sequence-like
chr19_-_51523272 0.270 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr19_-_51568323 0.264 NM_015596
KLK13
kallikrein-related peptidase 13
chr10_+_102107256 0.263


chr1_-_27998700 0.259 IFI6
interferon, alpha-inducible protein 6
chr9_-_139890984 0.259 NM_004669
CLIC3
chloride intracellular channel 3
chr19_+_54495541 0.258 NM_031897
NM_145814
NM_145815
CACNG6


calcium channel, voltage-dependent, gamma subunit 6


chr19_-_51327003 0.254 NM_002257
KLK1
kallikrein 1
chr22_-_37545944 0.247 NM_000878
IL2RB
interleukin 2 receptor, beta
chr1_+_26146376 0.244 NM_001099625
NM_001099627
FAM54B

family with sequence similarity 54, member B

chr1_+_6094342 0.243 NM_001199860
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr11_-_64528186 0.241 NM_001164716
NM_005609
PYGM

phosphorylase, glycogen, muscle

chr2_+_113816684 0.237 NM_012275
IL36RN
interleukin 36 receptor antagonist
chr19_-_51522953 0.237 NM_145888
KLK10
kallikrein-related peptidase 10
chr14_+_24867926 0.237 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr10_+_47083533 0.236 NM_005972
PPYR1
pancreatic polypeptide receptor 1
chr16_+_58498216 0.234 NDRG4
NDRG family member 4
chr2_-_241497367 0.232 ANKMY1
ankyrin repeat and MYND domain containing 1
chr1_-_2461683 0.231 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr13_+_113623496 0.226 NM_001112732
MCF2L
MCF.2 cell line derived transforming sequence-like
chr17_+_73629513 0.226 NM_001162995
C17orf109
chromosome 17 open reading frame 109
chr20_-_52790511 0.223 NM_000782
NM_001128915
CYP24A1

cytochrome P450, family 24, subfamily A, polypeptide 1

chr1_+_26146622 0.220 NM_019557
FAM54B
family with sequence similarity 54, member B
chr22_+_23229959 0.217 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr20_+_39969420 0.215 NM_022896
LPIN3
lipin 3
chr7_+_128580725 0.214 NM_001098627
IRF5
interferon regulatory factor 5
chr6_+_73331992 0.212 KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr22_-_39240016 0.212 NM_014293
NPTXR
neuronal pentraxin receptor
chr3_+_32280211 0.211 CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr18_-_28681885 0.211 NM_004949
NM_024422
DSC2

desmocollin 2

chr8_+_7738725 0.209 NM_001081551
DEFB103A
DEFB103B
defensin, beta 103A
defensin, beta 103B
chr3_-_45837912 0.207 SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr1_+_161129288 0.205 USP21
ubiquitin specific peptidase 21
chr1_+_26146446 0.205 FAM54B
family with sequence similarity 54, member B
chr6_-_43478423 0.201 NM_001012974
LRRC73
leucine rich repeat containing 73
chr1_+_180882312 0.201 NM_020950
KIAA1614
KIAA1614
chr1_+_161129229 0.197 NM_001014443
NM_012475
USP21

ubiquitin specific peptidase 21

chr7_+_75831194 0.197 NM_001110199
SRRM3
serine/arginine repetitive matrix 3
chr6_-_35109003 0.196 NM_001093728
NM_018679
TCP11

t-complex 11 homolog (mouse)

chr18_-_6414900 0.195 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr16_+_58534045 0.194 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr1_+_212788359 0.189 NM_001206486
ATF3
activating transcription factor 3
chr3_-_49058426 0.188 NM_018114
DALRD3
DALR anticodon binding domain containing 3
chr6_-_13295817 0.187 NM_001242698
LOC100130357
uncharacterized LOC100130357
chr11_-_2018885 0.185 H19
RPS12
H19, imprinted maternally expressed transcript (non-protein coding)
ribosomal protein S12
chr14_-_73493744 0.185 NM_021260
ZFYVE1
zinc finger, FYVE domain containing 1
chr3_+_154797644 0.185 NM_007287
MME
membrane metallo-endopeptidase
chr8_-_22089850 0.184 NM_001099335
NM_014759
PHYHIP

phytanoyl-CoA 2-hydroxylase interacting protein

chr1_+_109792640 0.184 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr10_+_83635069 0.184 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr20_-_60795270 0.183 NM_007232
HRH3
histamine receptor H3
chr1_-_24104743 0.183 LOC100506963
uncharacterized LOC100506963
chr11_+_369723 0.182 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr11_-_66445318 0.182 RBM4B
RNA binding motif protein 4B
chr21_-_43816123 0.180 NM_024022
NM_032405
TMPRSS3

transmembrane protease, serine 3

chr12_-_51717941 0.179 BIN2
bridging integrator 2
chr8_-_22089517 0.178 PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr15_-_83419125 0.178


chr11_-_66445218 0.178 NM_031492
RBM4B
RNA binding motif protein 4B
chr2_-_219906237 0.176 NM_152389
NM_194302
CCDC108

coiled-coil domain containing 108

chr11_+_46740736 0.176 NM_000506
F2
coagulation factor II (thrombin)
chr16_-_71264557 0.174 NM_032821
NM_017558
HYDIN

hydrocephalus inducing homolog (mouse)

chr7_-_98467483 0.173 TMEM130
transmembrane protein 130
chr11_+_46740769 0.173 F2
coagulation factor II (thrombin)
chr19_+_50691437 0.173 MYH14
myosin, heavy chain 14, non-muscle
chr2_-_239140214 0.172 LOC151174
uncharacterized LOC151174
chr2_+_109745996 0.172 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr6_-_10838712 0.171 NM_001242385
NM_001242957
NM_005906
MAK


male germ cell-associated kinase


chr12_+_10103914 0.171 NM_001207010
CLEC12A
C-type lectin domain family 12, member A
chr19_-_6502224 0.169 NM_006087
TUBB4A
tubulin, beta 4A class IVa
chr4_-_57522469 0.169 NM_001145459
NM_139211
HOPX

HOP homeobox

chr1_-_46089638 0.168 NM_001114938
NM_001190182
CCDC17

coiled-coil domain containing 17

chr15_-_45670955 0.163 NM_001482
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chrX_+_49019180 0.163 NM_001099681
NM_001099682
NM_024859
MAGIX


MAGI family member, X-linked


chr18_-_21242592 0.163 NM_173505
ANKRD29
ankyrin repeat domain 29
chr3_+_130745693 0.162 NM_001146003
NM_024800
NM_145910
NEK11


NIMA (never in mitosis gene a)- related kinase 11


chr8_-_33424642 0.159 NM_024787
RNF122
ring finger protein 122
chr1_-_214724844 0.158 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr8_-_145582111 0.157 NM_012162
NM_024555
FBXL6

F-box and leucine-rich repeat protein 6

chrX_-_153602928 0.157 FLNA
filamin A, alpha
chr13_+_52158483 0.156 NM_052950
WDFY2
WD repeat and FYVE domain containing 2
chr4_+_128651518 0.156 NM_031291
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr1_-_24741586 0.156 NM_001199012
C1orf201
chromosome 1 open reading frame 201
chr8_-_144241725 0.155 NM_001135655
LY6H
lymphocyte antigen 6 complex, locus H
chr18_+_10454625 0.154 APCDD1
adenomatosis polyposis coli down-regulated 1
chr18_+_10454620 0.154 NM_153000
APCDD1
adenomatosis polyposis coli down-regulated 1
chr15_-_45670624 0.154 GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr19_+_12949258 0.154 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr11_+_73359734 0.153 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr3_+_32280154 0.152 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr12_+_20848288 0.151 NM_001145945
NM_001145946
NM_001145944
NM_017435
SLCO1C1



solute carrier organic anion transporter family, member 1C1



chr1_-_203144910 0.150 NM_004997
MYBPH
myosin binding protein H
chr19_+_1524072 0.149 NM_001243079
PLK5
polo-like kinase 5
chr17_-_74581934 0.149 ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr2_-_241831385 0.149 NM_024861
C2orf54
chromosome 2 open reading frame 54
chr1_-_1051458 0.148 C1orf159
chromosome 1 open reading frame 159
chr19_-_41933255 0.147


chr7_+_192968 0.147 NM_020223
FAM20C
family with sequence similarity 20, member C
chr15_-_90349819 0.146 ANPEP
alanyl (membrane) aminopeptidase
chr12_-_51717905 0.146 NM_016293
BIN2
bridging integrator 2
chr2_+_131674223 0.145 NM_015320
NM_032995
ARHGEF4

Rho guanine nucleotide exchange factor (GEF) 4

chr12_-_57472547 0.145 TMEM194A
transmembrane protein 194A
chr19_-_12512022 0.145 NM_001080821
ZNF799
zinc finger protein 799
chr2_-_44065888 0.145 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr7_+_193112 0.145 FAM20C
family with sequence similarity 20, member C
chr11_+_111808017 0.145 DIXDC1
DIX domain containing 1
chr14_+_92790151 0.144 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr2_-_198175458 0.143 ANKRD44
ankyrin repeat domain 44
chr1_-_21044202 0.143 NM_001122819
NM_020816
KIF17

kinesin family member 17

chrX_-_153602998 0.142 NM_001110556
NM_001456
FLNA

filamin A, alpha

chr2_+_33738941 0.142 NM_015376
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr3_-_45838026 0.141 NM_020208
NM_022405
SLC6A20

solute carrier family 6 (proline IMINO transporter), member 20

chr7_-_75677317 0.141 NM_016086
STYXL1
serine/threonine/tyrosine interacting-like 1
chr10_+_99332197 0.141 NM_001129981
NM_020349
ANKRD2

ankyrin repeat domain 2 (stretch responsive muscle)

chr22_-_19137795 0.140 NM_005315
GSC2
goosecoid homeobox 2
chr3_+_154797910 0.140 NM_007288
MME
membrane metallo-endopeptidase
chr17_+_9548853 0.140 NM_153210
USP43
ubiquitin specific peptidase 43
chr17_-_46507481 0.139 NM_001075099
NM_003726
SKAP1

src kinase associated phosphoprotein 1

chr9_+_116356407 0.139 RGS3
regulator of G-protein signaling 3
chr16_+_2039945 0.139 NM_004209
SYNGR3
synaptogyrin 3
chr3_+_31574119 0.139 STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr1_-_204183036 0.139 NM_198447
GOLT1A
golgi transport 1A
chr14_-_106994001 0.138 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr14_-_95786095 0.138 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr8_+_104152876 0.137 NM_001024372
NM_024812
BAALC

brain and acute leukemia, cytoplasmic

chr3_+_6902797 0.137 NM_000844
NM_181874
GRM7

glutamate receptor, metabotropic 7

chr20_-_35580045 0.137 SAMHD1
SAM domain and HD domain 1
chr12_-_57472487 0.137 TMEM194A
transmembrane protein 194A
chr20_-_35580109 0.136 SAMHD1
SAM domain and HD domain 1
chr19_-_36001336 0.136 NM_001126059
DMKN
dermokine
chrX_+_152110214 0.136 NM_001178115
ZNF185
zinc finger protein 185 (LIM domain)
chr8_-_144241456 0.136 NM_002347
LY6H
lymphocyte antigen 6 complex, locus H
chr16_+_58497548 0.135 NM_020465
NDRG4
NDRG family member 4
chr15_-_40987284 0.133 LOC100505648
uncharacterized LOC100505648
chrX_+_70443055 0.133 NM_000166
GJB1
gap junction protein, beta 1, 32kDa
chr3_+_6902812 0.133 GRM7
glutamate receptor, metabotropic 7
chr17_+_12569206 0.132 NM_001146312
NM_153604
MYOCD

myocardin

chr12_-_57472573 0.131 NM_001130963
NM_015257
TMEM194A

transmembrane protein 194A

chr3_-_37217716 0.131 NM_001134369
NM_006309
NM_017724
LRRFIP2


leucine rich repeat (in FLII) interacting protein 2


chr2_-_38830068 0.131 HNRPLL
heterogeneous nuclear ribonucleoprotein L-like
chr9_-_130639939 0.131 NM_000476
AK1
adenylate kinase 1
chr6_+_42531951 0.130 UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr18_+_10454542 0.130 APCDD1
adenomatosis polyposis coli down-regulated 1
chr16_-_1968230 0.130 NM_001009606
HS3ST6
heparan sulfate (glucosamine) 3-O-sulfotransferase 6
chr6_+_132129195 0.129 ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr1_-_143467594 0.129


chr11_-_118016134 0.129 NM_001142349
SCN4B
sodium channel, voltage-gated, type IV, beta
chr10_-_97321094 0.129 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chr2_-_16847070 0.129 NM_030797
FAM49A
family with sequence similarity 49, member A
chr4_-_153700892 0.128 NM_145720
TIGD4
tigger transposable element derived 4
chr2_+_79252825 0.128 NM_001008387
NM_198448
REG3G

regenerating islet-derived 3 gamma

chr19_+_34745452 0.128 NM_014686
KIAA0355
KIAA0355
chr3_-_33759743 0.128 CLASP2
cytoplasmic linker associated protein 2
chr12_-_52604488 0.127 NM_001242696
LOC283403
uncharacterized LOC283403
chrX_-_153881757 0.126 NM_020994
NM_172377
CTAG2

cancer/testis antigen 2

chr16_-_75529289 0.126


chrX_+_134478671 0.126 NM_152695
ZNF449
zinc finger protein 449
chr19_-_14016908 0.126 NM_024323
C19orf57
chromosome 19 open reading frame 57
chr6_-_656943 0.125 NM_148959
HUS1B
HUS1 checkpoint homolog b (S. pombe)
chr11_-_30038487 0.125 NM_002233
KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr12_-_57472536 0.125 TMEM194A
transmembrane protein 194A
chr13_-_114103452 0.125 NM_199162
ADPRHL1
ADP-ribosylhydrolase like 1
chr20_+_33464327 0.124 NM_001076552
NM_018677
ACSS2

acyl-CoA synthetase short-chain family member 2

chr19_-_12551762 0.124 ZNF443
zinc finger protein 443
chr7_-_142583260 0.123 NM_018646
TRPV6
transient receptor potential cation channel, subfamily V, member 6
chr20_+_33464404 0.122 ACSS2
acyl-CoA synthetase short-chain family member 2
chr1_-_205325915 0.121 NM_018203
KLHDC8A
kelch domain containing 8A
chr12_+_119616594 0.120 NM_014365
HSPB8
heat shock 22kDa protein 8
chr3_+_154798078 0.120 NM_007289
MME
membrane metallo-endopeptidase
chr16_-_58231641 0.120 NM_001896
CSNK2A2
casein kinase 2, alpha prime polypeptide

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.21 4.90e-04 GO:0023052 signaling
1.20 1.11e-02 GO:0007165 signal transduction
1.18 1.21e-02 GO:0051716 cellular response to stimulus
1.38 3.19e-02 GO:0007154 cell communication
1.29 4.26e-02 GO:0023051 regulation of signaling
1.31 4.42e-02 GO:0009966 regulation of signal transduction
1.26 4.85e-02 GO:0048583 regulation of response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.31 1.40e-05 GO:0044459 plasma membrane part
1.54 9.07e-04 GO:0030054 cell junction
1.85 7.71e-03 GO:0030141 stored secretory granule
1.34 1.13e-02 GO:0000267 cell fraction
1.10 1.68e-02 GO:0016020 membrane
1.54 3.08e-02 GO:0044463 cell projection part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.53 2.61e-02 GO:0030695 GTPase regulator activity
1.10 3.88e-02 GO:0005515 protein binding
1.89 4.78e-02 GO:0005085 guanyl-nucleotide exchange factor activity