Motif ID: FOXO1,3,4.p2

Z-value: 1.125


Transcription factors associated with FOXO1,3,4.p2:

Gene SymbolEntrez IDGene Name
FOXO1 2308 forkhead box O1
FOXO3 2309 forkhead box O3
FOXO4 4303 forkhead box O4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXO3chr6_+_108882104-0.337.3e-02Click!
FOXO4chrX_+_70315637-0.232.2e-01Click!
FOXO1chr13_-_412406070.115.7e-01Click!


Activity profile for motif FOXO1,3,4.p2.

activity profile for motif FOXO1,3,4.p2


Sorted Z-values histogram for motif FOXO1,3,4.p2

Sorted Z-values for motif FOXO1,3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXO1,3,4.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_-_7921068 5.867 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr2_-_135782246 4.702 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr4_+_36285643 4.336 NM_001170700
DTHD1
death domain containing 1
chr9_-_3223007 4.066


chr13_-_39564857 3.370 NM_001144033
NM_145286
STOML3

stomatin (EPB72)-like 3

chr3_-_167371701 2.998 WDR49
WD repeat domain 49
chr11_+_73661363 2.438 NM_153614
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr5_+_10441973 2.418 NM_001201466
NM_031916
ROPN1L

rhophilin associated tail protein 1-like

chr22_-_50971007 2.287 NM_001014440
ODF3B
outer dense fiber of sperm tails 3B
chr3_-_150920946 2.282 NM_013308
GPR171
G protein-coupled receptor 171
chr10_+_23216953 2.265 NM_173081
ARMC3
armadillo repeat containing 3
chr4_-_100212085 2.233 NM_000667
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr5_-_110062365 2.096 NM_001039763
TMEM232
transmembrane protein 232
chr13_+_24144402 2.073 NM_001204459
NM_148957
TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr17_+_17876126 1.962 NM_001130090
NM_001130091
NM_001130092
NM_031294
LRRC48



leucine rich repeat containing 48



chr19_-_55677919 1.911 NM_178837
C19orf51
chromosome 19 open reading frame 51
chr9_-_117156684 1.843 NM_030767
AKNA
AT-hook transcription factor
chr3_+_108015392 1.774 HHLA2
HERV-H LTR-associating 2
chr1_-_161337663 1.754 NM_001013625
C1orf192
chromosome 1 open reading frame 192
chr4_+_186350543 1.738 NM_001114357
C4orf47
chromosome 4 open reading frame 47
chr19_+_41620336 1.699 NM_000774
CYP2F1
cytochrome P450, family 2, subfamily F, polypeptide 1
chr22_+_45809541 1.674 NM_015653
RIBC2
RIB43A domain with coiled-coils 2
chr9_+_12693385 1.669 NM_000550
TYRP1
tyrosinase-related protein 1
chr12_+_49297892 1.662 NM_033124
CCDC65
coiled-coil domain containing 65
chr2_-_217540722 1.548 IGFBP5
insulin-like growth factor binding protein 5
chr11_-_114466471 1.537 NM_001077639
NM_017678
FAM55D

family with sequence similarity 55, member D

chr22_+_45809599 1.533 RIBC2
RIB43A domain with coiled-coils 2
chr3_-_57530067 1.507 NM_178504
NM_198564
DNAH12

dynein, axonemal, heavy chain 12

chr6_+_43612766 1.470 NM_001193341
NM_152732
RSPH9

radial spoke head 9 homolog (Chlamydomonas)

chr9_-_3525721 1.352 RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr12_-_24103842 1.338 SOX5
SRY (sex determining region Y)-box 5
chr2_+_61389628 1.322 NM_001143959
C2orf74
chromosome 2 open reading frame 74
chr17_+_11786218 1.315 NM_004662
DNAH9
dynein, axonemal, heavy chain 9
chr3_+_98072697 1.300 NM_001005517
OR5K4
olfactory receptor, family 5, subfamily K, member 4
chr2_+_54558070 1.282 NM_001100396
C2orf73
chromosome 2 open reading frame 73
chr16_-_28621279 1.276 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr12_-_9268440 1.260 A2M
alpha-2-macroglobulin
chr12_-_9268522 1.227 NM_000014
A2M
alpha-2-macroglobulin
chr1_+_104198301 1.221 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr1_+_104292439 1.189 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr2_+_233498206 1.168 NM_025202
EFHD1
EF-hand domain family, member D1
chr12_-_9268513 1.163 A2M
alpha-2-macroglobulin
chr11_+_36616039 1.163 NM_138787
C11orf74
chromosome 11 open reading frame 74
chr1_+_104198140 1.162 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr1_+_104292278 1.150 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr17_+_68100994 1.116 NM_170742
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr6_+_127898318 1.075 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr1_-_20445991 1.072 NM_012400
PLA2G2D
phospholipase A2, group IID
chr11_-_114466397 1.060 FAM55D
family with sequence similarity 55, member D
chr1_-_157811491 1.059 NM_005894
CD5L
CD5 molecule-like
chr1_-_197036350 1.053 NM_001994
F13B
coagulation factor XIII, B polypeptide
chr4_-_177116713 1.042 NM_144644
SPATA4
spermatogenesis associated 4
chr1_+_47533046 1.016 NM_178134
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr7_+_37960920 1.015 NM_001242948
EPDR1
ependymin related protein 1 (zebrafish)
chr11_-_121986800 1.007 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr9_+_108424737 0.991 NM_005421
TAL2
T-cell acute lymphocytic leukemia 2
chr12_-_111358353 0.973 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr5_+_75699003 0.971 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr8_-_110655418 0.966 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr5_+_140247767 0.948 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr12_-_25801487 0.946 NM_001145727
IFLTD1
intermediate filament tail domain containing 1
chr3_+_151488214 0.941 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr5_-_41261539 0.940 NM_001115131
C6
complement component 6
chr2_+_29038862 0.925 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr1_+_63989012 0.918 NM_032437
EFCAB7
EF-hand calcium binding domain 7
chr1_+_20512577 0.900 NM_152376
UBXN10
UBX domain protein 10
chr20_+_56725982 0.897 NM_178456
C20orf85
chromosome 20 open reading frame 85
chr17_-_29641068 0.877 EVI2B
ecotropic viral integration site 2B
chr7_-_99573637 0.874 NM_001185
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr3_+_132316080 0.874 NM_016557
CCRL1
chemokine (C-C motif) receptor-like 1
chr12_-_10251520 0.869 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr12_-_9268475 0.866 A2M
alpha-2-macroglobulin
chr10_+_22540986 0.847 LOC100130992
uncharacterized LOC100130992
chr11_-_62476976 0.838 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr3_+_129159089 0.824 IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr11_-_85397215 0.822 NM_152723
CCDC89
coiled-coil domain containing 89
chr3_+_108021331 0.822 NM_007072
HHLA2
HERV-H LTR-associating 2
chr6_-_32557431 0.821 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr19_+_13134782 0.819 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr9_+_27109138 0.816 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr6_-_76782204 0.811 NM_001563
IMPG1
interphotoreceptor matrix proteoglycan 1
chr6_-_80247103 0.809 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr8_-_72459891 0.806


chr3_+_129159075 0.804 IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr8_+_79578258 0.803 NM_016010
FAM164A
family with sequence similarity 164, member A
chr9_-_86432546 0.798 NM_001135953
NM_025211
GKAP1

G kinase anchoring protein 1

chr17_-_39316982 0.796 NM_032524
KRTAP4-4
keratin associated protein 4-4
chr1_+_241695433 0.780 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr7_+_134832765 0.769 NM_018295
TMEM140
transmembrane protein 140
chr1_-_57431620 0.769 NM_000066
C8B
complement component 8, beta polypeptide
chr3_+_129159138 0.762 IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr9_+_124922189 0.761 NM_198469
MORN5
MORN repeat containing 5
chr1_-_216978708 0.759 NM_001243514
ESRRG
estrogen-related receptor gamma
chr11_+_17332454 0.758


chr2_-_217560247 0.749 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr18_-_24765178 0.738 NM_031422
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr17_-_19290471 0.736 NM_001198695
NM_002404
MFAP4

microfibrillar-associated protein 4

chr1_+_171217632 0.735 NM_002021
FMO1
flavin containing monooxygenase 1
chr3_-_165555252 0.734 NM_000055
BCHE
butyrylcholinesterase
chr18_-_40695483 0.732 NM_002930
RIT2
Ras-like without CAAX 2
chr1_-_7973286 0.729 UTS2
urotensin 2
chr16_+_69958900 0.728 NM_199424
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr3_-_52488030 0.727 NM_003280
TNNC1
troponin C type 1 (slow)
chr7_+_120628867 0.725 C7orf58
chromosome 7 open reading frame 58
chr17_-_39306053 0.723 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr18_-_58040000 0.719 NM_005912
MC4R
melanocortin 4 receptor
chr1_+_12806162 0.716 NM_152290
C1orf158
chromosome 1 open reading frame 158
chr3_-_12200850 0.710 NM_003256
TIMP4
TIMP metallopeptidase inhibitor 4
chr3_+_129159150 0.704 IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr10_-_116286570 0.699 ABLIM1
actin binding LIM protein 1
chr16_-_68033355 0.696 NM_022355
DPEP2
dipeptidase 2
chr3_-_47957475 0.696


chr21_+_25801042 0.689 FLJ42200
FLJ42200 protein
chr17_+_39382878 0.679 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr8_-_133772808 0.676 NM_001145153
NM_144649
TMEM71

transmembrane protein 71

chr11_+_73359734 0.674 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr14_+_21156922 0.674 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr5_+_121465214 0.674 NM_207317
ZNF474
zinc finger protein 474
chr7_-_141673572 0.671 NM_176817
TAS2R38
taste receptor, type 2, member 38
chr1_-_42776760 0.670


chr17_+_30814708 0.669


chr20_-_3762060 0.664 NM_015417
SPEF1
sperm flagellar 1
chr8_-_145838887 0.664 NM_025251
ARHGAP39
Rho GTPase activating protein 39
chr3_-_71179736 0.657 FOXP1
forkhead box P1
chr1_-_27998719 0.652 NM_002038
NM_022872
NM_022873
IFI6


interferon, alpha-inducible protein 6


chr16_-_53737713 0.652 NM_001127897
NM_015272
RPGRIP1L

RPGRIP1-like

chr6_-_87804773 0.651 NM_000735
NM_001252383
CGA

glycoprotein hormones, alpha polypeptide

chr4_-_38806410 0.650 NM_003263
TLR1
toll-like receptor 1
chr11_-_5526833 0.647 NM_001005567
OR51B5
HBE1
olfactory receptor, family 51, subfamily B, member 5
hemoglobin, epsilon 1
chr1_-_57044980 0.644 PPAP2B
phosphatidic acid phosphatase type 2B
chr11_-_70858241 0.641 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr10_-_61900659 0.637 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_+_74347461 0.637 NM_001133
AFM
afamin
chr16_+_80574853 0.635 NM_130897
DYNLRB2
dynein, light chain, roadblock-type 2
chr19_-_14939275 0.633 NM_017506
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr17_+_39405938 0.631 NM_033191
KRTAP9-4
keratin associated protein 9-4
chr11_+_10879763 0.630 LOC729013
uncharacterized LOC729013
chr9_+_66553254 0.627 MGC21881
uncharacterized locus MGC21881
chr9_+_134000939 0.625 NM_005085
NUP214
nucleoporin 214kDa
chr2_-_86565205 0.620 NM_001164730
REEP1
receptor accessory protein 1
chr1_-_104238785 0.619 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr17_-_72709010 0.615 NM_139018
CD300LF
CD300 molecule-like family member f
chr5_-_169724614 0.614 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chrX_+_49217770 0.612 NM_001098405
GAGE12F
GAGE4
GAGE5
GAGE7
GAGE12E
G antigen 12F
G antigen 4
G antigen 5
G antigen 7
G antigen 12E
chr10_+_102732285 0.610 NM_001203244
NM_017893
SEMA4G

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G

chr4_-_100273831 0.609 NM_000669
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr1_+_64936475 0.607 NM_020925
CACHD1
cache domain containing 1
chr9_-_3525973 0.606 NM_002919
NM_134428
RFX3

regulatory factor X, 3 (influences HLA class II expression)

chr6_-_130031278 0.596 NM_033515
ARHGAP18
Rho GTPase activating protein 18
chr1_-_104239071 0.596 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr9_+_74729510 0.596 NM_001242507
GDA
guanine deaminase
chr22_-_17747520 0.590 CECR3
cat eye syndrome chromosome region, candidate 3 (non-protein coding)
chr1_-_27998658 0.589 IFI6
interferon, alpha-inducible protein 6
chr4_-_138453628 0.587 NM_019035
PCDH18
protocadherin 18
chr6_+_131958441 0.587 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr16_+_56225301 0.582 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr6_-_10838712 0.578 NM_001242385
NM_001242957
NM_005906
MAK


male germ cell-associated kinase


chr11_-_8739398 0.578 ST5
suppression of tumorigenicity 5
chr9_+_20658307 0.577 NM_017794
KIAA1797
KIAA1797
chr9_+_120466453 0.572 NM_138554
TLR4
toll-like receptor 4
chr14_-_21271002 0.566 NM_002933
NM_198234
NM_198235
RNASE1


ribonuclease, RNase A family, 1 (pancreatic)


chr1_-_161207879 0.563 NM_001077469
NM_001077470
NM_001077471
NM_001077472
NM_001077473
NM_001077474
NM_001077475
NM_001077476
NM_001077477
NM_001077478
NM_001077479
NM_001077480
NM_001077481
NM_001077482
NM_005122
NR1I3














nuclear receptor subfamily 1, group I, member 3














chr15_+_72978519 0.562 NM_001252678
NM_033028
BBS4

Bardet-Biedl syndrome 4

chr1_-_169703178 0.562 NM_000450
SELE
selectin E
chr10_-_50732142 0.560 NM_170753
PGBD3
piggyBac transposable element derived 3
chr12_-_8043743 0.559 SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr1_-_27998700 0.557 IFI6
interferon, alpha-inducible protein 6
chr4_+_88896868 0.545 SPP1
secreted phosphoprotein 1
chr12_-_131002409 0.545 NM_015347
RIMBP2
RIMS binding protein 2
chr1_+_10490158 0.542 NM_198544
NM_199006
NM_199294
APITD1-CORT

APITD1
APITD1-CORT readthrough

apoptosis-inducing, TAF9-like domain 1
chr6_+_112375277 0.538 NM_003880
NM_198239
WISP3

WNT1 inducible signaling pathway protein 3

chr14_+_92788924 0.535 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr21_-_43771069 0.533 NM_005423
TFF2
trefoil factor 2
chrX_-_114252132 0.533 NM_000640
IL13RA2
interleukin 13 receptor, alpha 2
chr12_-_15374290 0.530 NM_001190726
NM_032918
RERG

RAS-like, estrogen-regulated, growth inhibitor

chr7_-_6098813 0.524 NM_001134335
NM_014413
EIF2AK1

eukaryotic translation initiation factor 2-alpha kinase 1

chr1_+_162602308 0.523 DDR2
discoidin domain receptor tyrosine kinase 2
chr8_-_26724748 0.522 ADRA1A
adrenergic, alpha-1A-, receptor
chr21_-_40816127 0.522 NM_152505
LCA5L
Leber congenital amaurosis 5-like
chr11_+_62104773 0.520 NM_001083926
NM_025080
ASRGL1

asparaginase like 1

chr11_-_10673832 0.519 NM_001098579
MRVI1
murine retrovirus integration site 1 homolog
chr4_-_164534656 0.510 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr1_+_162602198 0.509 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr19_-_7293876 0.509 NM_000208
NM_001079817
INSR

insulin receptor

chr14_-_81405883 0.505 NM_152446
CEP128
centrosomal protein 128kDa
chr4_+_70916158 0.500 NM_002159
HTN1
histatin 1
chr8_+_18079176 0.499 NM_001160174
NAT1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr7_+_120628722 0.499 NM_024913
C7orf58
chromosome 7 open reading frame 58
chr3_-_93782066 0.498 NM_001195643
DHFRL1
dihydrofolate reductase-like 1
chr9_+_74920329 0.496


chr1_-_27701302 0.493 NM_003665
NM_173452
FCN3

ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)

chr17_-_54893249 0.490 NM_001085430
C17orf67
chromosome 17 open reading frame 67
chr2_-_71454200 0.489 NM_020459
PAIP2B
poly(A) binding protein interacting protein 2B
chr2_-_211018294 0.488 C2orf67
chromosome 2 open reading frame 67
chr17_-_40897025 0.483 NM_001991
EZH1
enhancer of zeste homolog 1 (Drosophila)
chr4_-_170077807 0.483 SH3RF1
SH3 domain containing ring finger 1
chr2_-_27712520 0.482 NM_015662
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr12_-_57472487 0.482 TMEM194A
transmembrane protein 194A
chr17_+_67410825 0.478 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr17_-_40021616 0.478 NM_018143
KLHL11
kelch-like 11 (Drosophila)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.45 9.48e-03 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen