Motif ID: FOXP3.p2

Z-value: 0.795


Transcription factors associated with FOXP3.p2:

Gene SymbolEntrez IDGene Name
FOXP3 50943 forkhead box P3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXP3chrX_-_49121171-0.115.6e-01Click!


Activity profile for motif FOXP3.p2.

activity profile for motif FOXP3.p2


Sorted Z-values histogram for motif FOXP3.p2

Sorted Z-values for motif FOXP3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXP3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_34381497 6.873 NM_001252195
NM_147168
NM_147169
C9orf24


chromosome 9 open reading frame 24


chr3_-_19975671 3.657 NM_144715
EFHB
EF-hand domain family, member B
chr6_+_88117689 2.648 NM_001031743
C6orf165
chromosome 6 open reading frame 165
chr5_+_140213968 2.635 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr6_-_32497925 2.620 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr3_+_63638343 2.581 NM_001080537
SNTN
sentan, cilia apical structure protein
chr12_-_25801487 2.467 NM_001145727
IFLTD1
intermediate filament tail domain containing 1
chr1_-_161337663 2.460 NM_001013625
C1orf192
chromosome 1 open reading frame 192
chr13_+_43355685 2.315 NM_182508
C13orf30
chromosome 13 open reading frame 30
chr6_-_32557431 2.156 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr11_-_62475060 1.512 NM_001122955
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_-_62474666 1.430 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr17_-_29641068 1.215 EVI2B
ecotropic viral integration site 2B
chr11_+_124824076 1.198 CCDC15
coiled-coil domain containing 15
chr6_-_154677868 1.125 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chrX_+_105412297 1.023 NM_001171020
NM_152423
MUM1L1

melanoma associated antigen (mutated) 1-like 1

chr1_-_94586678 1.001 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr10_+_114135013 0.960 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr17_-_10421858 0.954 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr11_-_8892909 0.947 ST5
suppression of tumorigenicity 5
chr3_+_186560478 0.944 ADIPOQ
adiponectin, C1Q and collagen domain containing
chr20_-_7921068 0.934 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr6_-_76203256 0.912 NM_015687
FILIP1
filamin A interacting protein 1
chr11_+_71900601 0.899 NM_016724
NM_016725
FOLR1

folate receptor 1 (adult)

chr3_+_186560462 0.876 NM_001177800
NM_004797
ADIPOQ

adiponectin, C1Q and collagen domain containing

chr1_-_150738292 0.860 NM_001199739
NM_004079
CTSS

cathepsin S

chr5_+_121465214 0.858 NM_207317
ZNF474
zinc finger protein 474
chr1_+_46646199 0.830 TSPAN1
tetraspanin 1
chr1_+_104159953 0.828 NM_000699
AMY2A
amylase, alpha 2A (pancreatic)
chr15_-_55800431 0.801 NM_001033559
NM_001033560
NM_130810
DYX1C1


dyslexia susceptibility 1 candidate 1


chr11_-_62474869 0.777 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr5_-_110062365 0.772 NM_001039763
TMEM232
transmembrane protein 232
chr6_-_25874439 0.770 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr6_+_31730772 0.759 NM_001039651
C6orf26
chromosome 6 open reading frame 26
chr1_+_174844655 0.738 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr3_-_57312979 0.714 NM_130387
ASB14
ankyrin repeat and SOCS box containing 14
chr11_-_62474810 0.700 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr5_-_41213513 0.693 NM_000065
C6
complement component 6
chrX_-_135863502 0.679 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_-_8219001 0.678 C3AR1
complement component 3a receptor 1
chr14_+_21498344 0.652 NM_173846
TPPP2
tubulin polymerization-promoting protein family member 2
chr1_-_150738232 0.618 CTSS
cathepsin S
chr7_-_16921596 0.595 NM_176813
AGR3
anterior gradient 3 homolog (Xenopus laevis)
chr3_+_132036276 0.592 ACPP
acid phosphatase, prostate
chr11_+_71900958 0.586 NM_000802
FOLR1
folate receptor 1 (adult)
chr2_-_110962577 0.559 NM_000272
NM_001128178
NM_001128179
NM_207181
NPHP1



nephronophthisis 1 (juvenile)



chr17_+_6659155 0.555 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr3_+_361365 0.551 NM_001253388
CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr7_+_48211054 0.542 NM_152701
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr11_-_85437457 0.539 NM_206927
NM_206928
SYTL2

synaptotagmin-like 2

chr17_+_51900238 0.534 NM_032559
KIF2B
kinesin family member 2B
chr16_-_52581713 0.480 NM_001146188
TOX3
TOX high mobility group box family member 3
chr5_+_61874561 0.472 NM_181506
LRRC70
leucine rich repeat containing 70
chr12_-_8218930 0.467 NM_004054
C3AR1
complement component 3a receptor 1
chr15_+_45021319 0.465 TRIM69
tripartite motif containing 69
chr9_+_12693385 0.459 NM_000550
TYRP1
tyrosinase-related protein 1
chr14_-_20774089 0.449 TTC5
tetratricopeptide repeat domain 5
chr12_+_56075418 0.438 METTL7B
methyltransferase like 7B
chr17_+_39405938 0.422 NM_033191
KRTAP9-4
keratin associated protein 9-4
chr4_-_186300151 0.420 NM_018409
LRP2BP
LRP2 binding protein
chr20_+_9288446 0.412 NM_000933
PLCB4
phospholipase C, beta 4
chr4_-_100356290 0.411 NM_001166504
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr19_-_45579687 0.398 NM_145288
ZNF296
zinc finger protein 296
chr3_+_149192479 0.395 TM4SF4
transmembrane 4 L six family member 4
chr4_-_54424402 0.391 NM_032622
LNX1
ligand of numb-protein X 1
chr17_+_6659356 0.389 XAF1
XIAP associated factor 1
chr1_-_150669499 0.389 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr9_-_75567915 0.382 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr14_-_20774129 0.378 NM_138376
TTC5
tetratricopeptide repeat domain 5
chr17_-_29641094 0.377 NM_006495
EVI2B
ecotropic viral integration site 2B
chr4_-_100356449 0.374 NM_000673
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr12_+_51318515 0.368 NM_014033
METTL7A
methyltransferase like 7A
chr1_-_207095198 0.357 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr11_+_124824012 0.357 NM_025004
CCDC15
coiled-coil domain containing 15
chr17_+_39382878 0.344 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr4_+_187070326 0.336 NM_001006655
FAM149A
family with sequence similarity 149, member A
chr1_+_15990300 0.336


chr3_+_2933898 0.335 NM_001206956
NM_175613
CNTN4

contactin 4

chr12_-_10562744 0.326 NM_001199805
KLRC4-KLRK1
KLRC4-KLRK1 readthrough
chr17_-_39306053 0.324 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr4_+_15779887 0.324 NM_001775
CD38
CD38 molecule
chr6_+_30908776 0.322 NM_080870
DPCR1
diffuse panbronchiolitis critical region 1
chr7_+_142560512 0.319 EPHB6
EPH receptor B6
chr15_-_93277303 0.313 FAM174B
family with sequence similarity 174, member B
chr16_-_12897632 0.310 CPPED1
calcineurin-like phosphoesterase domain containing 1
chr8_-_139926235 0.303 NM_152888
COL22A1
collagen, type XXII, alpha 1
chr1_+_40859016 0.300 NM_001198979
SMAP2
small ArfGAP2
chr11_-_66445218 0.295 NM_031492
RBM4B
RNA binding motif protein 4B
chr3_-_121264780 0.290 NM_199420
POLQ
polymerase (DNA directed), theta
chr11_-_31014232 0.289 NM_020869
DCDC5
doublecortin domain containing 5
chr10_+_96443250 0.285 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr15_-_43513196 0.284 EPB42
erythrocyte membrane protein band 4.2
chr12_+_102271349 0.281 DRAM1
DNA-damage regulated autophagy modulator 1
chr3_+_132036210 0.280 NM_001099
NM_001134194
ACPP

acid phosphatase, prostate

chr8_+_76452202 0.277 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr3_+_149192367 0.271 NM_004617
TM4SF4
transmembrane 4 L six family member 4
chrX_-_117119282 0.268 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr19_-_44831907 0.266 ZFP112
zinc finger protein 112 homolog (mouse)
chr2_+_152214105 0.265 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chrX_-_135863033 0.260 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr6_+_33043702 0.259 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr7_-_142659397 0.256 KEL
Kell blood group, metallo-endopeptidase
chr20_+_29956420 0.253 NM_054112
DEFB118
defensin, beta 118
chr2_+_191002485 0.250 NM_001042521
C2orf88
chromosome 2 open reading frame 88
chr5_+_140571903 0.249 NM_018930
PCDHB10
protocadherin beta 10
chr1_+_174417211 0.247 NM_005684
GPR52
G protein-coupled receptor 52
chr6_+_144612872 0.247 NM_007124
UTRN
utrophin
chr20_+_15177503 0.245 NM_001033087
MACROD2
MACRO domain containing 2
chrM_+_4770 0.245


chr21_-_33957746 0.243 NM_144659
TCP10L
t-complex 10 (mouse)-like
chr11_-_66445318 0.241 RBM4B
RNA binding motif protein 4B
chr3_-_15798057 0.241 NM_001195099
ANKRD28
ankyrin repeat domain 28
chr11_+_118175294 0.237 NM_000733
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr1_-_93399531 0.226


chrX_-_135338640 0.225 NM_001173516
MAP7D3
MAP7 domain containing 3
chr4_-_54424345 0.224 LNX1
ligand of numb-protein X 1
chr17_-_63822660 0.224 NM_001037325
CEP112
centrosomal protein 112kDa
chr2_+_170366211 0.217 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr1_-_173886401 0.209 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr20_-_270957 0.202 C20orf96
chromosome 20 open reading frame 96
chr20_+_24929862 0.200 NM_003650
CST7
cystatin F (leukocystatin)
chr17_+_60447578 0.199 NM_001144933
EFCAB3
EF-hand calcium binding domain 3
chr6_-_24383519 0.195 NM_001195610
DCDC2
doublecortin domain containing 2
chr16_-_70099755 0.195 PDXDC2P
pyridoxal-dependent decarboxylase domain containing 2, pseudogene
chr2_+_65663812 0.195 FLJ16124
FLJ16124 protein
chr2_+_166152282 0.193 NM_001040143
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr7_-_142659412 0.191 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr1_-_151804225 0.191 NM_005060
RORC
RAR-related orphan receptor C
chr19_-_6720585 0.188 NM_000064
C3
complement component 3
chr2_+_102770401 0.186 NM_000877
IL1R1
interleukin 1 receptor, type I
chr16_-_12897693 0.185 NM_001099455
NM_018340
CPPED1

calcineurin-like phosphoesterase domain containing 1

chr6_+_46761093 0.182 NM_005588
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr15_+_43885251 0.180 NM_020990
CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr18_-_74729049 0.179 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr5_+_43602738 0.176 NM_012343
NNT
nicotinamide nucleotide transhydrogenase
chr1_-_203144910 0.173 NM_004997
MYBPH
myosin binding protein H
chrX_+_8432870 0.170 NM_001001888
VCX3B
VCX3A
variable charge, X-linked 3B
variable charge, X-linked 3A
chr1_+_244216506 0.168 NM_006352
ZNF238
zinc finger protein 238
chr8_+_17829848 0.168 PCM1
pericentriolar material 1
chr2_+_103035148 0.166 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr6_-_32634287 0.166 NM_001243961
NM_002123
HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

chr4_-_7436614 0.164 NM_001085382
PSAPL1
prosaposin-like 1 (gene/pseudogene)
chr16_+_31085722 0.163 NM_014699
ZNF646
zinc finger protein 646
chr17_+_28268622 0.163 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr1_-_120935893 0.161 FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr18_+_3594056 0.160 FLJ35776
uncharacterized LOC649446
chr3_-_170744458 0.156 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr6_+_43457214 0.153 NM_001146017
TJAP1
tight junction associated protein 1 (peripheral)
chr4_+_88896801 0.153 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr12_-_3982394 0.152 NM_020367
PARP11
poly (ADP-ribose) polymerase family, member 11
chr6_-_38563763 0.152 NM_001172418
NM_152733
BTBD9

BTB (POZ) domain containing 9

chr18_+_32173281 0.152 NM_001128175
NM_001198938
NM_001198939
NM_001198940
DTNA



dystrobrevin, alpha



chrX_-_8139307 0.150 NM_016378
VCX2
variable charge, X-linked 2
chr19_-_36545646 0.150 NM_152658
THAP8
THAP domain containing 8
chr8_-_133772808 0.150 NM_001145153
NM_144649
TMEM71

transmembrane protein 71

chr4_-_186697065 0.149 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr12_+_53497273 0.147 NM_003578
SOAT2
sterol O-acyltransferase 2
chr13_+_78315294 0.146 NM_001242869
NM_001242870
NM_001242871
NM_144595
SLAIN1



SLAIN motif family, member 1



chr11_-_57158103 0.145 NM_001243245
NM_002728
PRG2

proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)

chrX_+_102965836 0.144 NM_182541
TMEM31
transmembrane protein 31
chr19_+_4278597 0.141 NM_020209
SHD
Src homology 2 domain containing transforming protein D
chr10_-_72545110 0.139 NM_152710
C10orf27
chromosome 10 open reading frame 27
chr17_+_3118911 0.138 NM_014565
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr15_+_48498497 0.137 NM_000338
NM_001184832
SLC12A1

solute carrier family 12 (sodium/potassium/chloride transporters), member 1

chr1_+_2938045 0.137 NM_080431
ACTRT2
actin-related protein T2
chr12_+_50024326 0.137 NM_001031698
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr9_-_116840604 0.133 AMBP
alpha-1-microglobulin/bikunin precursor
chr1_+_32674694 0.133 NM_001099434
DCDC2B
doublecortin domain containing 2B
chr11_-_62783281 0.133 NM_001184732
NM_001184733
NM_001184736
NM_004254
SLC22A8



solute carrier family 22 (organic anion transporter), member 8



chr5_+_140552201 0.132 NM_018940
PCDHB7
protocadherin beta 7
chr17_+_67410825 0.131 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr3_-_50608421 0.131 NM_001171741
C3orf18
chromosome 3 open reading frame 18
chr6_-_167797917 0.131 NM_004610
TCP10
t-complex 10 homolog (mouse)
chrX_+_36065052 0.130 NM_173695
CXorf59
chromosome X open reading frame 59
chr3_-_172241060 0.129 NM_001190943
NM_001190942
NM_003810
TNFSF10


tumor necrosis factor (ligand) superfamily, member 10


chr6_+_87969619 0.128 ZNF292
zinc finger protein 292
chr1_+_196621007 0.128 NM_000186
NM_001014975
CFH

complement factor H

chr16_+_19727698 0.127 NM_153208
IQCK
IQ motif containing K
chr17_-_29641087 0.126 EVI2B
ecotropic viral integration site 2B
chrX_-_117107700 0.126 NM_033495
NM_001168300
KLHL13

kelch-like 13 (Drosophila)

chrX_-_135863104 0.125 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr2_+_61389628 0.125 NM_001143959
C2orf74
chromosome 2 open reading frame 74
chr19_+_13134782 0.124 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_-_247921707 0.122 NM_012353
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chrX_-_100307042 0.121 TRMT2B
TRM2 tRNA methyltransferase 2 homolog B (S. cerevisiae)
chr14_-_89016806 0.120 PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr14_-_64108534 0.119 NM_080666
WDR89
WD repeat domain 89
chr9_-_117265452 0.117 NM_001083885
DFNB31
deafness, autosomal recessive 31
chr6_+_30104509 0.116 NM_138700
TRIM40
tripartite motif containing 40
chr16_+_31085751 0.116 ZNF646
zinc finger protein 646
chr7_+_123485222 0.115 NM_012269
HYAL4
hyaluronoglucosaminidase 4
chr1_-_204459445 0.113 NM_002646
PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr18_-_74728963 0.112 MBP
myelin basic protein
chr1_-_173886464 0.110 NM_000488
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr19_-_23578226 0.107 NM_003430
ZNF91
zinc finger protein 91
chr20_-_44006876 0.106 NM_014477
TP53TG5
TP53 target 5
chr1_-_246580710 0.106 NM_022743
SMYD3
SET and MYND domain containing 3
chr16_+_15068832 0.106 NM_015027
PDXDC1
pyridoxal-dependent decarboxylase domain containing 1
chr19_-_40440532 0.106 NM_003890
FCGBP
Fc fragment of IgG binding protein
chr2_+_198570027 0.105 NM_138395
MARS2
methionyl-tRNA synthetase 2, mitochondrial

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
14.23 1.95e-02 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
2.82 3.37e-02 GO:0045087 innate immune response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
13.83 2.86e-02 GO:0042613 MHC class II protein complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.54 4.61e-02 GO:0004091 carboxylesterase activity