Motif ID: GATA6.p2

Z-value: 0.987


Transcription factors associated with GATA6.p2:

Gene SymbolEntrez IDGene Name
GATA6 2627 GATA binding protein 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA6chr18_+_197494030.346.5e-02Click!


Activity profile for motif GATA6.p2.

activity profile for motif GATA6.p2


Sorted Z-values histogram for motif GATA6.p2

Sorted Z-values for motif GATA6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_33795558 2.594 NM_002771
PRSS3
protease, serine, 3
chr1_-_153044083 2.332 NM_001017418
SPRR2B
small proline-rich protein 2B
chrX_+_37865834 2.331 NM_001163335
NM_138780
SYTL5

synaptotagmin-like 5

chr8_+_54764367 2.126 NM_170587
RGS20
regulator of G-protein signaling 20
chr1_-_205391180 2.015 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr8_+_124194751 1.825 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr2_+_27719702 1.795 NM_001486
GCKR
glucokinase (hexokinase 4) regulator
chr12_-_91505541 1.716 NM_002345
LUM
lumican
chr1_-_24469571 1.660 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr4_-_159093717 1.637 NM_016613
FAM198B
family with sequence similarity 198, member B
chr4_-_159094163 1.534 NM_001031700
NM_001128424
FAM198B

family with sequence similarity 198, member B

chr4_+_169013687 1.522 NM_007193
ANXA10
annexin A10
chr8_+_124194873 1.505 FAM83A
family with sequence similarity 83, member A
chr9_+_33240165 1.463 NM_014471
SPINK4
serine peptidase inhibitor, Kazal type 4
chr11_-_58343308 1.447 NM_004811
LPXN
leupaxin
chr7_+_142457318 1.417 NM_002769
PRSS1
PRSS2
protease, serine, 1 (trypsin 1)
protease, serine, 2 (trypsin 2)
chr3_-_137851123 1.367 NM_016161
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr7_-_100239136 1.360 NM_003227
TFR2
transferrin receptor 2
chr12_+_107974633 1.332 NM_001017523
BTBD11
BTB (POZ) domain containing 11
chr11_-_124310980 1.184 NM_012378
OR8B8
olfactory receptor, family 8, subfamily B, member 8
chr6_+_12290528 1.137 NM_001168319
NM_001955
EDN1

endothelin 1

chr19_+_10397642 1.136 NM_001039132
NM_001544
NM_022377
ICAM4


intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)


chr21_+_43823970 1.066 NM_001001895
NM_001243467
NM_018961
UBASH3A


ubiquitin associated and SH3 domain containing A


chr20_-_54967221 1.014 NM_003600
NM_198433
NM_198434
NM_198435
NM_198436
NM_198437
AURKA





aurora kinase A





chr7_-_142659397 1.011 KEL
Kell blood group, metallo-endopeptidase
chrX_-_55057408 1.007 NM_000032
NM_001037967
NM_001037968
ALAS2


aminolevulinate, delta-, synthase 2


chr7_-_142659412 0.995 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr2_+_113885145 0.980 IL1RN
interleukin 1 receptor antagonist
chr2_+_102927961 0.967 NM_016232
IL18R1
IL1RL1
interleukin 18 receptor 1
interleukin 1 receptor-like 1
chr12_+_4430346 0.918 NM_020375
C12orf5
chromosome 12 open reading frame 5
chr2_-_208994408 0.904 NM_020989
CRYGC
crystallin, gamma C
chr21_-_39870303 0.883 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chrX_+_135278912 0.882 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr6_+_31674639 0.878 NM_001003693
LY6G6F
lymphocyte antigen 6 complex, locus G6F
chrX_-_78623006 0.855 NM_001171581
NM_004867
ITM2A

integral membrane protein 2A

chr2_+_90077732 0.849


chr19_+_7741934 0.848 NM_174918
C19orf59
chromosome 19 open reading frame 59
chr4_+_72897520 0.842 NM_004885
NPFFR2
neuropeptide FF receptor 2
chr10_+_118187381 0.841 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr9_+_125137600 0.836 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_216259197 0.806 FN1
fibronectin 1
chrX_+_15525430 0.789 NM_001721
BMX
BMX non-receptor tyrosine kinase
chr8_+_70378858 0.785 NM_001128204
NM_015170
SULF1

sulfatase 1

chr1_-_42630386 0.781 NM_033553
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr4_-_103265818 0.774 SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr11_-_59612925 0.774 NM_005142
GIF
gastric intrinsic factor (vitamin B synthesis)
chr10_-_7682741 0.759 ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr15_-_74495528 0.752 NM_001142618
STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr11_+_61008643 0.750 NM_014224
PGA5
pepsinogen 5, group I (pepsinogen A)
chr9_-_21142143 0.743 NM_002177
IFNW1
interferon, omega 1
chr9_-_114937464 0.743 NM_022486
SUSD1
sushi domain containing 1
chr1_+_202431870 0.740 NM_032103
NM_032104
PPP1R12B

protein phosphatase 1, regulatory subunit 12B

chr7_+_150690838 0.728 NM_001160109
NM_001160110
NM_001160111
NOS3


nitric oxide synthase 3 (endothelial cell)


chr17_+_74381186 0.693 NM_001142602
SPHK1
sphingosine kinase 1
chrX_+_107288199 0.679 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr6_-_49604524 0.675 NM_000324
RHAG
Rh-associated glycoprotein
chr6_-_46047978 0.674 NM_001114086
CLIC5
chloride intracellular channel 5
chr6_-_35765056 0.672 NM_001252597
NM_001252598
NM_001832
CLPS


colipase, pancreatic


chr2_+_158958381 0.668 NM_173355
UPP2
uridine phosphorylase 2
chr8_-_23712297 0.666 NM_003155
STC1
stanniocalcin 1
chr11_-_19082227 0.660 NM_054030
MRGPRX2
MAS-related GPR, member X2
chr9_+_35673852 0.651 NM_001216
CA9
carbonic anhydrase IX
chr18_-_64271215 0.648 NM_021153
CDH19
cadherin 19, type 2
chr10_+_75673346 0.639 PLAU
plasminogen activator, urokinase
chr17_+_19314490 0.631 NM_007148
RNF112
ring finger protein 112
chr1_+_32043745 0.624 NM_001204415
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr10_+_11206928 0.620 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr13_+_31309644 0.614 NM_001629
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr4_-_120243257 0.609 NM_000134
FABP2
fatty acid binding protein 2, intestinal
chr20_+_58251715 0.606 NM_001199506
PHACTR3
phosphatase and actin regulator 3
chr1_-_209825673 0.605 NM_001127641
LAMB3
laminin, beta 3
chr12_+_100041527 0.605 NM_153364
FAM71C
family with sequence similarity 71, member C
chr11_+_10326618 0.603 NM_001124
ADM
adrenomedullin
chr19_+_35849487 0.602 NM_005304
FFAR3
free fatty acid receptor 3
chrX_+_85517970 0.600 NM_001139515
DACH2
dachshund homolog 2 (Drosophila)
chr5_+_131409484 0.588 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr10_-_48416692 0.585 NM_016204
GDF2
growth differentiation factor 2
chr17_+_7905911 0.585 NM_000180
GUCY2D
guanylate cyclase 2D, membrane (retina-specific)
chr2_+_171034654 0.583 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr2_-_44065888 0.582 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr17_+_39555993 0.576 GAST
gastrin
chr2_+_220436953 0.573 NM_002191
INHA
inhibin, alpha
chr19_-_48547180 0.564 NM_019855
CABP5
calcium binding protein 5
chr16_+_202853 0.557 NM_005332
HBZ
hemoglobin, zeta
chr12_+_119616594 0.554 NM_014365
HSPB8
heat shock 22kDa protein 8
chr4_-_74853819 0.549 NM_002704
PPBP
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr10_+_11207053 0.543 CELF2
CUGBP, Elav-like family member 2
chr13_+_31309690 0.534 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr9_+_135937364 0.525 NM_001807
CEL
carboxyl ester lipase (bile salt-stimulated lipase)
chr1_+_115572414 0.521 NM_000549
TSHB
thyroid stimulating hormone, beta
chr5_-_63257959 0.520 HTR1A
5-hydroxytryptamine (serotonin) receptor 1A
chrX_+_44703248 0.513 NM_022076
DUSP21
dual specificity phosphatase 21
chr22_-_37584254 0.508 NM_031910
NM_182486
C1QTNF6

C1q and tumor necrosis factor related protein 6

chr8_+_32579350 0.507 NM_001159996
NRG1
neuregulin 1
chr2_-_122159140 0.504 CLASP1
cytoplasmic linker associated protein 1
chr17_-_2966900 0.500 NM_014566
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chr6_-_117996369 0.497


chr7_-_44180911 0.492 NM_021223
MYL7
myosin, light chain 7, regulatory
chr6_+_167704802 0.492 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr11_+_63974190 0.491 FERMT3
fermitin family member 3
chr11_-_125550674 0.491 NM_001612
NM_020069
NM_020107
NM_020108
ACRV1



acrosomal vesicle protein 1



chr5_+_143191725 0.485 NM_021182
HMHB1
histocompatibility (minor) HB-1
chr8_+_120079423 0.484 NM_006438
COLEC10
collectin sub-family member 10 (C-type lectin)
chr3_-_48040260 0.484 MAP4
microtubule-associated protein 4
chr8_+_12803150 0.483 NM_020844
KIAA1456
KIAA1456
chr1_-_158656487 0.481 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr1_-_120354058 0.480 NM_001159352
NM_001159353
NM_032044
REG4


regenerating islet-derived family, member 4


chr5_-_131879172 0.479 NM_000879
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr2_+_113885137 0.479 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr2_+_90211704 0.479


chr17_-_64225496 0.475 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr19_+_40146533 0.475 NM_001190441
LGALS16
lectin, galactoside-binding, soluble, 16
chr4_-_123377471 0.472 NM_000586
IL2
interleukin 2
chr15_-_34610928 0.472 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr4_-_52883785 0.467 NM_001024611
LRRC66
leucine rich repeat containing 66
chr8_-_124749573 0.466 NM_001003954
NM_004306
ANXA13

annexin A13

chr9_-_117692874 0.466 NM_001244
NM_001252290
TNFSF8

tumor necrosis factor (ligand) superfamily, member 8

chr18_+_29171729 0.463 NM_000371
TTR
transthyretin
chr7_+_130020289 0.462 NM_001868
CPA1
carboxypeptidase A1 (pancreatic)
chr4_+_155484131 0.459 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chrX_+_38211735 0.457 NM_000531
OTC
ornithine carbamoyltransferase
chr12_+_8666135 0.455 NM_080387
CLEC4D
C-type lectin domain family 4, member D
chr14_-_81864726 0.454 NM_033104
STON2
stonin 2
chr11_-_57148602 0.452 NM_006093
PRG3
proteoglycan 3
chr12_-_120765555 0.451 NM_000928
PLA2G1B
phospholipase A2, group IB (pancreas)
chr20_+_43029973 0.447 HNF4A
hepatocyte nuclear factor 4, alpha
chr20_-_30060815 0.447 NM_001037500
DEFB124
defensin, beta 124
chr2_+_239008950 0.441 NM_194312
ESPNL
espin-like
chr3_-_187009469 0.440 NM_001031849
NM_001879
NM_139125
MASP1


mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)


chr5_-_16742336 0.439 MYO10
myosin X
chr21_+_39628869 0.437 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_-_88427535 0.437 NM_001443
FABP1
fatty acid binding protein 1, liver
chr16_-_67977956 0.437 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr3_-_128186090 0.426 NM_153330
DNAJB8
DnaJ (Hsp40) homolog, subfamily B, member 8
chr11_+_92085261 0.425 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr4_-_15939949 0.423 FGFBP1
fibroblast growth factor binding protein 1
chr4_-_189026401 0.422 NM_173553
TRIML2
tripartite motif family-like 2
chr3_+_130569368 0.422 NM_001199180
NM_001199181
NM_001199182
ATP2C1


ATPase, Ca++ transporting, type 2C, member 1


chr3_+_189507448 0.422 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr14_-_69445978 0.421 ACTN1
actinin, alpha 1
chr3_+_186915273 0.420 NM_153708
RTP1
receptor (chemosensory) transporter protein 1
chrX_+_99899388 0.414 SRPX2
sushi-repeat containing protein, X-linked 2
chr12_-_68619535 0.410 NM_018402
IL26
interleukin 26
chr9_+_118916069 0.407 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr1_+_119957553 0.404 NM_001166120
HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr8_+_22019167 0.400 NM_001172357
NM_001172410
NM_003018
SFTPC


surfactant protein C


chr21_+_37536838 0.394 NM_005128
DOPEY2
dopey family member 2
chr1_+_50574601 0.392 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr3_+_133495925 0.390 TF
transferrin
chr15_+_67418053 0.384 NM_001145102
SMAD3
SMAD family member 3
chr13_+_32313678 0.381 NM_001166058
NM_130806
RXFP2

relaxin/insulin-like family peptide receptor 2

chr17_-_73840495 0.377 UNC13D
unc-13 homolog D (C. elegans)
chr12_-_91573264 0.377 NM_133503
DCN
decorin
chr17_-_42466840 0.376 NM_000419
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr10_+_71075609 0.375 NM_033496
HK1
hexokinase 1
chr1_-_161207879 0.372 NM_001077469
NM_001077470
NM_001077471
NM_001077472
NM_001077473
NM_001077474
NM_001077475
NM_001077476
NM_001077477
NM_001077478
NM_001077479
NM_001077480
NM_001077481
NM_001077482
NM_005122
NR1I3














nuclear receptor subfamily 1, group I, member 3














chr17_+_75283972 0.368 NM_001113492
SEPT9
septin 9
chr19_+_8117645 0.368 NM_001201359
NM_005624
CCL25

chemokine (C-C motif) ligand 25

chr1_+_159175048 0.365 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr18_-_44561967 0.364 NM_016427
TCEB3B
transcription elongation factor B polypeptide 3B (elongin A2)
chr11_-_66206260 0.364 NM_016050
NM_170738
NM_170739
MRPL11


mitochondrial ribosomal protein L11


chr19_-_48059112 0.364 NM_001101419
ZNF541
zinc finger protein 541
chr12_-_53601051 0.362 ITGB7
integrin, beta 7
chr10_+_18689512 0.362 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr12_-_14849427 0.357 NM_004963
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr11_+_131240370 0.356 NM_001048209
NTM
neurotrimin
chr5_+_34687663 0.347 NM_001145523
RAI14
retinoic acid induced 14
chr12_-_91576579 0.344 DCN
decorin
chrX_+_7137471 0.342 NM_000351
STS
steroid sulfatase (microsomal), isozyme S
chr3_-_195538699 0.341 NM_004532
NM_018406
NM_138297
MUC4


mucin 4, cell surface associated


chr19_+_30863318 0.340 NM_014717
ZNF536
zinc finger protein 536
chr9_+_139557378 0.339 NM_016215
EGFL7
EGF-like-domain, multiple 7
chr18_+_43304143 0.338 SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr22_+_36649172 0.337 APOL1
apolipoprotein L, 1
chr3_-_194188967 0.336 NM_024524
ATP13A3
ATPase type 13A3
chr8_+_7738908 0.334 NM_018661
DEFB103B
defensin, beta 103B
chr4_-_76928601 0.332 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chrX_+_135251795 0.330 NM_001167819
FHL1
four and a half LIM domains 1
chr1_-_55089068 0.326 NM_176782
FAM151A
family with sequence similarity 151, member A
chr12_-_53228061 0.324 NM_175834
KRT79
keratin 79
chr10_-_90712510 0.324 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chrX_+_106161589 0.316 NM_001171095
CLDN2
claudin 2
chr1_+_202172863 0.313 NM_021636
LGR6
leucine-rich repeat containing G protein-coupled receptor 6
chr17_+_9729380 0.312 NM_004246
GLP2R
glucagon-like peptide 2 receptor
chr1_-_209825797 0.312 NM_000228
LAMB3
laminin, beta 3
chrX_+_99899162 0.311 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr2_-_2334887 0.310 NM_015025
MYT1L
myelin transcription factor 1-like
chr22_+_23229959 0.310 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr17_+_74536114 0.308 NM_001077620
PRCD
progressive rod-cone degeneration
chr3_+_158991035 0.308 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr6_-_29395489 0.308 NM_013937
OR11A1
olfactory receptor, family 11, subfamily A, member 1
chr2_-_45795104 0.307 SRBD1
S1 RNA binding domain 1
chr9_-_130616957 0.306 ENG
endoglin
chr1_+_63063186 0.305 NM_014495
ANGPTL3
angiopoietin-like 3
chr5_-_160112266 0.304 ATP10B
ATPase, class V, type 10B
chr18_+_19749403 0.304 NM_005257
GATA6
GATA binding protein 6
chr17_+_38171613 0.304 NM_000759
NM_001178147
NM_172219
NM_172220
CSF3



colony stimulating factor 3 (granulocyte)



chr1_-_42384370 0.304 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr6_-_30128688 0.302 NM_006778
NM_052828
TRIM10

tripartite motif containing 10

chr5_+_156607847 0.301 NM_005546
ITK
IL2-inducible T-cell kinase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.48 7.69e-13 GO:0032501 multicellular organismal process
1.80 9.23e-11 GO:0065008 regulation of biological quality
3.48 2.35e-07 GO:0008202 steroid metabolic process
1.33 2.60e-07 GO:0050896 response to stimulus
1.62 2.43e-06 GO:0042221 response to chemical stimulus
4.87 2.72e-06 GO:0007586 digestion
3.96 3.56e-06 GO:0042445 hormone metabolic process
3.50 4.60e-06 GO:0010817 regulation of hormone levels
2.22 3.19e-05 GO:0048878 chemical homeostasis
1.49 4.58e-05 GO:0048731 system development
1.62 6.31e-05 GO:0048513 organ development
1.92 7.04e-05 GO:0006629 lipid metabolic process
1.96 7.04e-05 GO:0009611 response to wounding
4.94 8.08e-05 GO:0034754 cellular hormone metabolic process
1.44 1.59e-04 GO:0048856 anatomical structure development
2.30 1.61e-04 GO:0001775 cell activation
2.15 4.97e-04 GO:0050878 regulation of body fluid levels
2.87 7.08e-04 GO:0030168 platelet activation
1.21 7.13e-04 GO:0065007 biological regulation
4.67 1.11e-03 GO:0042446 hormone biosynthetic process
2.24 1.16e-03 GO:0050801 ion homeostasis
1.36 1.37e-03 GO:0032502 developmental process
1.38 1.50e-03 GO:0007275 multicellular organismal development
3.44 1.54e-03 GO:0006805 xenobiotic metabolic process
3.44 1.54e-03 GO:0071466 cellular response to xenobiotic stimulus
1.34 1.64e-03 GO:0051716 cellular response to stimulus
3.42 1.75e-03 GO:0009410 response to xenobiotic stimulus
1.58 1.75e-03 GO:0003008 system process
7.85 1.97e-03 GO:0008207 C21-steroid hormone metabolic process
2.17 2.11e-03 GO:0007599 hemostasis
2.24 2.16e-03 GO:0055082 cellular chemical homeostasis
2.26 2.21e-03 GO:0006873 cellular ion homeostasis
2.10 2.47e-03 GO:0007186 G-protein coupled receptor protein signaling pathway
1.84 2.54e-03 GO:0042592 homeostatic process
4.36 2.83e-03 GO:0002576 platelet degranulation
2.04 3.44e-03 GO:0042060 wound healing
2.90 3.85e-03 GO:0003013 circulatory system process
2.90 3.85e-03 GO:0008015 blood circulation
2.14 4.24e-03 GO:0007596 blood coagulation
2.14 4.24e-03 GO:0050817 coagulation
9.53 7.15e-03 GO:0006700 C21-steroid hormone biosynthetic process
2.50 8.85e-03 GO:0055065 metal ion homeostasis
1.33 9.60e-03 GO:0023052 signaling
2.35 1.10e-02 GO:0055080 cation homeostasis
2.42 1.15e-02 GO:0030003 cellular cation homeostasis
8.97 1.17e-02 GO:0050892 intestinal absorption
2.50 1.25e-02 GO:0006875 cellular metal ion homeostasis
10.90 1.43e-02 GO:0008211 glucocorticoid metabolic process
10.90 1.43e-02 GO:0044241 lipid digestion
3.56 2.05e-02 GO:0006694 steroid biosynthetic process
13.62 2.14e-02 GO:0006704 glucocorticoid biosynthetic process
2.11 2.16e-02 GO:0046903 secretion
5.32 2.61e-02 GO:0006721 terpenoid metabolic process
2.88 2.81e-02 GO:0010876 lipid localization
1.33 3.03e-02 GO:0007165 signal transduction
1.69 3.33e-02 GO:0009605 response to external stimulus
6.46 4.18e-02 GO:0050886 endocrine process
17.43 4.52e-02 GO:0006705 mineralocorticoid biosynthetic process
17.43 4.52e-02 GO:0008212 mineralocorticoid metabolic process
1.94 4.81e-02 GO:0019725 cellular homeostasis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.07 7.63e-20 GO:0005576 extracellular region
2.60 2.50e-14 GO:0005615 extracellular space
2.34 8.54e-14 GO:0044421 extracellular region part
1.38 2.14e-06 GO:0071944 cell periphery
1.37 1.46e-05 GO:0005886 plasma membrane
1.47 8.34e-04 GO:0044459 plasma membrane part
2.62 5.52e-03 GO:0030141 stored secretory granule
4.61 6.29e-03 GO:0031983 vesicle lumen
4.64 1.42e-02 GO:0031093 platelet alpha granule lumen
4.21 1.56e-02 GO:0031091 platelet alpha granule
4.54 1.72e-02 GO:0034774 secretory granule lumen
4.36 2.49e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.40 1.85e-05 GO:0008289 lipid binding
1.83 6.27e-05 GO:0005102 receptor binding
2.91 1.37e-03 GO:0005126 cytokine receptor binding
2.81 1.59e-03 GO:0005125 cytokine activity
4.02 1.74e-02 GO:0005496 steroid binding
3.51 2.00e-02 GO:0004867 serine-type endopeptidase inhibitor activity
3.30 2.22e-02 GO:0005179 hormone activity
8.17 2.46e-02 GO:0008395 steroid hydroxylase activity