Motif ID: GCUACAU

Z-value: 0.427


Mature miRNA associated with seed GCUACAU:

NamemiRBase Accession
hsa-miR-221 MIMAT0000278
hsa-miR-222 MIMAT0000279



Activity profile for motif GCUACAU.

activity profile for motif GCUACAU


Sorted Z-values histogram for motif GCUACAU

Sorted Z-values for motif GCUACAU



Network of associatons between targets according to the STRING database.



First level regulatory network of GCUACAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_40398286 0.792 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr15_-_40398573 0.781 NM_033503
BMF
Bcl2 modifying factor
chr15_-_40401041 0.723 NM_001003940
BMF
Bcl2 modifying factor
chr4_+_72052354 0.699 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr6_+_16129285 0.572 NM_013262
MYLIP
myosin regulatory light chain interacting protein
chr16_+_28303622 0.572 NM_001024401
SBK1
SH3-binding domain kinase 1
chr3_-_145968958 0.518 NM_001128306
NM_001177304
NM_020353
PLSCR4


phospholipid scramblase 4


chr4_+_72204769 0.479 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr4_+_55523906 0.453 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr1_+_114496498 0.427 NM_181358
HIPK1
homeodomain interacting protein kinase 1
chr1_+_114493766 0.420 NM_198269
HIPK1
homeodomain interacting protein kinase 1
chrX_-_44202834 0.375 NM_025184
EFHC2
EF-hand domain (C-terminal) containing 2
chr17_-_47439326 0.357 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr7_+_114055048 0.338 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr6_-_56112315 0.331 NM_030820
COL21A1
collagen, type XXI, alpha 1
chr5_+_140254930 0.307 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr5_+_140213968 0.305 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr14_+_74111577 0.301 NM_001201366
NM_031427
DNAL1

dynein, axonemal, light chain 1

chr5_+_140220811 0.300 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr5_+_140186658 0.295 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr15_+_82555101 0.290 NM_001008226
FAM154B
family with sequence similarity 154, member B
chr16_+_15596122 0.288 NM_001142469
C16orf45
chromosome 16 open reading frame 45
chr10_+_120789227 0.284 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr13_-_36705513 0.279 NM_004734
DCLK1
doublecortin-like kinase 1
chr3_+_3841079 0.262 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr13_-_36429798 0.260 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr5_+_140247767 0.253 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr2_-_213403280 0.253 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr2_-_24149899 0.247 NM_001242338
NM_017552
ATAD2B

ATPase family, AAA domain containing 2B

chr1_-_204329043 0.247 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr16_+_15528324 0.237 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr7_+_94285620 0.232 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr1_-_156051788 0.230 NM_001093725
MEX3A
mex-3 homolog A (C. elegans)
chr7_+_94285676 0.228 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr16_+_69599868 0.221 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr18_-_53255734 0.220 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr12_+_12869818 0.219 NM_004064
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr2_-_170550859 0.215 NM_001085447
C2orf77
chromosome 2 open reading frame 77
chr8_+_28747885 0.212 NM_001135726
HMBOX1
homeobox containing 1
chr8_-_52811707 0.207 NM_052937
PCMTD1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr5_+_140165875 0.207 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr10_+_93170086 0.205 NM_173497
NM_182765
HECTD2

HECT domain containing 2

chr15_+_57210823 0.200 NM_003205
NM_207036
NM_207037
NM_207038
TCF12



transcription factor 12



chr7_+_121513158 0.198 NM_001206838
NM_001206839
NM_002851
PTPRZ1


protein tyrosine phosphatase, receptor-type, Z polypeptide 1


chr6_+_17281773 0.193 NM_001143942
RBM24
RNA binding motif protein 24
chr6_+_17282931 0.190 NM_153020
RBM24
RNA binding motif protein 24
chr5_+_140207562 0.188 NM_018909
NM_031848
NM_031849
PCDHA6


protocadherin alpha 6


chr6_+_17282294 0.188 NM_001143941
RBM24
RNA binding motif protein 24
chr8_-_110657745 0.186 NM_001099751
NM_001099752
SYBU

syntabulin (syntaxin-interacting)

chr8_-_110657025 0.183 NM_001099753
NM_001099754
NM_001099755
SYBU


syntabulin (syntaxin-interacting)


chr8_-_110661007 0.182 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr2_-_152955502 0.180 NM_000726
NM_001145798
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr3_+_183353355 0.178 NM_017644
KLHL24
kelch-like 24 (Drosophila)
chr8_-_110693233 0.178 NM_001099745
NM_001099746
SYBU

syntabulin (syntaxin-interacting)

chr8_-_110704019 0.177 NM_001099743
NM_001099744
SYBU

syntabulin (syntaxin-interacting)

chr5_+_56469655 0.175 NM_001203246
NM_022913
GPBP1

GC-rich promoter binding protein 1

chr5_+_56509900 0.173 NM_001127236
GPBP1
GC-rich promoter binding protein 1
chr2_-_152955208 0.173 NM_001005746
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr8_-_110655418 0.172 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr2_+_111878450 0.172 NM_001204106
NM_001204107
NM_001204108
NM_001204109
NM_001204110
NM_001204111
NM_001204112
NM_001204113
NM_006538
NM_138621
NM_138622
NM_138623
NM_138624
NM_138625
NM_138626
NM_138627
NM_207002
NM_207003
BCL2L11

















BCL2-like 11 (apoptosis facilitator)

















chr4_+_40751913 0.169 NM_024677
NSUN7
NOP2/Sun domain family, member 7
chr15_-_52970808 0.166 NM_019600
FAM214A
family with sequence similarity 214, member A
chr9_-_75568232 0.165 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr1_+_26438267 0.163 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr6_-_111804413 0.163 NM_002912
REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr4_-_55991746 0.162 NM_002253
KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr15_+_57511616 0.162 NM_207040
TCF12
transcription factor 12
chr21_-_43373938 0.158 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr3_+_169684549 0.157 NM_003262
SEC62
SEC62 homolog (S. cerevisiae)
chr2_-_68479481 0.156 NM_000945
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr16_-_30798206 0.156 NM_001080417
ZNF629
zinc finger protein 629
chr2_-_152830448 0.156 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr5_+_140345746 0.155 NM_018899
PCDHAC2
protocadherin alpha subfamily C, 2
chr12_-_56652118 0.153 NM_173595
ANKRD52
ankyrin repeat domain 52
chr5_-_146889618 0.152 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr8_+_28748030 0.151 NM_024567
HMBOX1
homeobox containing 1
chr5_+_56471272 0.151 NM_001127235
GPBP1
GC-rich promoter binding protein 1
chr1_+_220701547 0.150 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1
chr5_-_146833150 0.149 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr10_-_53459309 0.147 NM_015235
CSTF2T
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr16_-_66730466 0.145 NM_178818
NM_181521
CMTM4

CKLF-like MARVEL transmembrane domain containing 4

chr5_+_140180782 0.142 NM_018906
NM_031497
PCDHA3

protocadherin alpha 3

chr8_-_23712297 0.138 NM_003155
STC1
stanniocalcin 1
chr19_+_1248548 0.136 NM_177401
MIDN
midnolin
chr17_-_63557615 0.135 NM_004655
AXIN2
axin 2
chr6_-_52926588 0.135 NM_014920
NM_016513
ICK

intestinal cell (MAK-like) kinase

chr17_-_58603492 0.135 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr4_+_184826427 0.134 NM_020225
STOX2
storkhead box 2
chr13_+_20532906 0.132 NM_001190965
ZMYM2
zinc finger, MYM-type 2
chr12_+_12938540 0.128 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr6_+_37225506 0.128 NM_017772
TBC1D22B
TBC1 domain family, member 22B
chr3_+_16926451 0.128 NM_001144382
PLCL2
phospholipase C-like 2
chr9_+_74729510 0.127 NM_001242507
GDA
guanine deaminase
chr7_-_25164902 0.127 NM_018947
CYCS
cytochrome c, somatic
chr10_-_94050799 0.127 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr2_-_27851744 0.124 NM_001142683
NM_024584
CCDC121

coiled-coil domain containing 121

chr5_+_140261792 0.123 NM_018904
NM_031865
PCDHA13

protocadherin alpha 13

chr13_-_41706587 0.123 NM_152903
KBTBD6
kelch repeat and BTB (POZ) domain containing 6
chr16_+_68119211 0.122 NM_004555
NM_173163
NM_173165
NFATC3


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3


chr13_+_20532788 0.118 NM_003453
NM_197968
NM_001190964
ZMYM2


zinc finger, MYM-type 2


chr2_-_190445521 0.115 NM_014585
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr17_+_36861857 0.115 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr9_+_2015218 0.113 NM_003070
NM_139045
SMARCA2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr3_+_140660639 0.110 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr1_+_179923870 0.110 NM_014810
CEP350
centrosomal protein 350kDa
chr16_+_54965110 0.109 NM_001252197
NM_005853
IRX5

iroquois homeobox 5

chr10_-_99094427 0.109 NM_012083
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr10_-_126480349 0.109 NM_212554
METTL10
methyltransferase like 10
chr12_-_22487566 0.108 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr2_-_179315756 0.107 NM_003690
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr2_-_179315354 0.107 NM_001139518
NM_001139517
PRKRA

protein kinase, interferon-inducible double stranded RNA dependent activator

chr1_-_10856704 0.105 NM_001079843
NM_017766
CASZ1

castor zinc finger 1

chr3_-_184870727 0.104 NM_001025266
C3orf70
chromosome 3 open reading frame 70
chr4_-_185395616 0.104 NM_002199
IRF2
interferon regulatory factor 2
chr9_-_125027080 0.103 NM_033117
RBM18
RNA binding motif protein 18
chr1_-_89357246 0.100 NM_001514
GTF2B
general transcription factor IIB
chr9_-_15510899 0.099 NM_001128217
NM_033222
PSIP1

PC4 and SFRS1 interacting protein 1

chr21_-_43346780 0.099 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr15_-_56535475 0.098 NM_022841
RFX7
regulatory factor X, 7
chr2_-_20189775 0.098 NM_001006657
NM_020779
WDR35

WD repeat domain 35

chr10_-_94003002 0.096 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr3_+_16974581 0.095 NM_015184
PLCL2
phospholipase C-like 2
chr5_-_157285977 0.094 NM_001195555
NM_001195556
NM_014666
CLINT1


clathrin interactor 1


chr3_-_11761946 0.094 NM_014667
VGLL4
vestigial like 4 (Drosophila)
chr8_-_93978264 0.094 NM_001191035
NM_001171795
NM_001171796
NM_001171797
NM_001171798
NM_001171799
C8orf83





chromosome 8 open reading frame 83





chr12_+_6898605 0.093 NM_000616
NM_001195014
NM_001195015
NM_001195016
NM_001195017
CD4




CD4 molecule




chr5_-_9546157 0.092 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr5_+_138677517 0.092 NM_016480
PAIP2
poly(A) binding protein interacting protein 2
chr1_+_14075861 0.091 NM_001007257
PRDM2
PR domain containing 2, with ZNF domain
chr10_+_114709963 0.091 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr1_+_114471995 0.091 NM_152696
NM_198268
HIPK1

homeodomain interacting protein kinase 1

chr4_+_106816593 0.091 NM_001033047
NM_001184690
NM_001184691
NM_001184692
NM_001184693
NPNT




nephronectin




chr1_+_150980895 0.091 NM_021222
PRUNE
prune homolog (Drosophila)
chr18_+_11751470 0.090 NM_001142339
NM_002071
GNAL

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type

chr8_+_79428335 0.090 NM_006823
NM_181839
PKIA

protein kinase (cAMP-dependent, catalytic) inhibitor alpha

chr11_-_74178593 0.090 NM_005472
KCNE3
potassium voltage-gated channel, Isk-related family, member 3
chr17_-_27621163 0.089 NM_020772
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr12_+_120427476 0.089 NM_207311
CCDC64
coiled-coil domain containing 64
chr5_-_43557520 0.089 NM_183323
PAIP1
poly(A) binding protein interacting protein 1
chr13_+_88324777 0.088 NM_015567
SLITRK5
SLIT and NTRK-like family, member 5
chr12_+_41831484 0.088 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr20_+_11898536 0.087 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr17_+_60556247 0.087 NM_001112707
NM_006852
TLK2

tousled-like kinase 2

chr5_+_141488314 0.086 NM_030571
NDFIP1
Nedd4 family interacting protein 1
chr3_+_69812961 0.086 NM_006722
MITF
microphthalmia-associated transcription factor
chr15_+_47476225 0.086 NM_001198999
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr5_+_67584251 0.085 NM_181524
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr14_-_53019036 0.085 NM_001160047
NM_020784
TXNDC16

thioredoxin domain containing 16

chr14_-_36278335 0.085 NM_014990
NM_194301
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr5_+_67511578 0.085 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr20_-_40246991 0.084 NM_032221
CHD6
chromodomain helicase DNA binding protein 6
chr12_+_41582167 0.083 NM_001164595
PDZRN4
PDZ domain containing ring finger 4
chr13_-_111567415 0.083 NM_017664
ANKRD10
ankyrin repeat domain 10
chr18_-_19284737 0.083 NM_138340
ABHD3
abhydrolase domain containing 3
chr5_+_79703792 0.082 NM_001105251
NM_014733
ZFYVE16

zinc finger, FYVE domain containing 16

chr18_-_25757351 0.082 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr2_-_160472960 0.082 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr9_-_37465384 0.082 NM_014872
ZBTB5
zinc finger and BTB domain containing 5
chr11_+_45868956 0.082 NM_021117
CRY2
cryptochrome 2 (photolyase-like)
chr9_-_112260529 0.081 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr1_+_74663895 0.081 NM_001112808
NM_001199327
NM_001199328
NM_001199329
NM_003838
FPGT-TNNI3K

FPGT


FPGT-TNNI3K readthrough

fucose-1-phosphate guanylyltransferase


chr11_+_45868668 0.080 NM_001127457
CRY2
cryptochrome 2 (photolyase-like)
chr16_+_19535178 0.080 NM_001199022
NM_014711
CCP110

centriolar coiled coil protein 110kDa

chr7_-_99679192 0.080 NM_017715
NM_032924
ZNF3

zinc finger protein 3

chr2_+_109335906 0.080 NM_006267
RANBP2
RAN binding protein 2
chr5_+_67586466 0.079 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_-_57045235 0.079 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chrX_+_17393537 0.079 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr1_-_86174088 0.078 NM_001170670
NM_017953
ZNHIT6

zinc finger, HIT-type containing 6

chr4_+_4291923 0.078 NM_145291
ZBTB49
zinc finger and BTB domain containing 49
chr2_+_149632772 0.078 NM_004522
KIF5C
kinesin family member 5C
chr9_+_96338671 0.077 NM_005392
PHF2
PHD finger protein 2
chr5_+_140235594 0.076 NM_018901
NM_031859
NM_031860
PCDHA10


protocadherin alpha 10


chr1_-_155881163 0.076 NM_006912
RIT1
Ras-like without CAAX 1
chr3_-_11610264 0.076 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr1_-_20126368 0.075 NM_181719
TMCO4
transmembrane and coiled-coil domains 4
chrX_+_17653412 0.075 NM_001136024
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr1_-_224033673 0.075 NM_001031685
NM_005426
TP53BP2

tumor protein p53 binding protein, 2

chr3_-_11685395 0.074 NM_001128219
VGLL4
vestigial like 4 (Drosophila)
chr8_-_27472298 0.074 NM_001831
CLU
clusterin
chr2_-_100106478 0.073 NM_001037872
NM_016316
REV1

REV1 homolog (S. cerevisiae)

chr11_+_100557851 0.073 NM_152432
ARHGAP42
Rho GTPase activating protein 42
chr3_+_69915374 0.073 NM_198177
MITF
microphthalmia-associated transcription factor
chr7_+_23636970 0.073 NM_138771
CCDC126
coiled-coil domain containing 126
chr21_+_40177847 0.073 NM_005239
ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr17_+_38171613 0.072 NM_000759
NM_001178147
NM_172219
NM_172220
CSF3



colony stimulating factor 3 (granulocyte)



chr3_-_11623829 0.071 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr1_+_46806389 0.071 NM_199044
NSUN4
NOP2/Sun domain family, member 4
chr5_+_67588395 0.071 NM_001242466
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr6_-_161694992 0.071 NM_020133
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr4_-_89618928 0.071 NM_153757
NAP1L5
nucleosome assembly protein 1-like 5
chr10_-_75335415 0.071 NM_152586
USP54
ubiquitin specific peptidase 54
chr6_+_90539569 0.069 NM_001137667
NM_001137668
NM_012115
CASP8AP2


caspase 8 associated protein 2


chr3_+_69812620 0.068 NM_001184967
MITF
microphthalmia-associated transcription factor
chr9_-_74383301 0.068 NM_001135820
NM_013390
TMEM2

transmembrane protein 2

chr20_+_56964162 0.067 NM_001195677
NM_004738
VAPB

VAMP (vesicle-associated membrane protein)-associated protein B and C

chr5_-_175964223 0.067 NM_014901
RNF44
ring finger protein 44
chr13_-_86373328 0.067 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr11_+_48002063 0.067 NM_001098503
NM_002843
PTPRJ

protein tyrosine phosphatase, receptor type, J

chr3_+_69788562 0.067 NM_198159
MITF
microphthalmia-associated transcription factor

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.74 3.79e-04 GO:0007156 homophilic cell adhesion
2.18 9.48e-04 GO:0010605 negative regulation of macromolecule metabolic process
2.10 1.44e-03 GO:0009892 negative regulation of metabolic process
1.61 2.09e-03 GO:0010468 regulation of gene expression
2.42 2.92e-03 GO:0010629 negative regulation of gene expression
2.11 4.05e-03 GO:0031324 negative regulation of cellular metabolic process
1.41 4.69e-03 GO:0044260 cellular macromolecule metabolic process
3.06 5.18e-03 GO:0016337 cell-cell adhesion
2.43 7.68e-03 GO:0051253 negative regulation of RNA metabolic process
2.32 1.06e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.29 1.37e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
3.00 1.94e-02 GO:0010608 posttranscriptional regulation of gene expression
1.56 2.76e-02 GO:0048519 negative regulation of biological process
2.32 3.65e-02 GO:0045892 negative regulation of transcription, DNA-dependent
2.15 3.78e-02 GO:0031327 negative regulation of cellular biosynthetic process
2.20 3.96e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.42 2.63e-06 GO:0005634 nucleus
1.15 3.62e-03 GO:0005622 intracellular
2.12 3.88e-03 GO:0044451 nucleoplasm part
1.77 5.62e-03 GO:0005654 nucleoplasm
1.14 1.07e-02 GO:0044424 intracellular part
7.77 2.43e-02 GO:0000932 cytoplasmic mRNA processing body
1.19 2.44e-02 GO:0043231 intracellular membrane-bounded organelle
1.19 2.67e-02 GO:0043227 membrane-bounded organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.30 8.61e-05 GO:0005515 protein binding
3.32 5.55e-04 GO:0003702 RNA polymerase II transcription factor activity
1.15 6.30e-04 GO:0005488 binding
1.49 7.10e-04 GO:0003676 nucleic acid binding
2.85 3.72e-03 GO:0016564 transcription repressor activity
1.84 2.12e-02 GO:0030528 transcription regulator activity
1.37 2.18e-02 GO:0046872 metal ion binding
1.36 2.36e-02 GO:0043169 cation binding
15.53 2.52e-02 GO:0045295 gamma-catenin binding
1.36 2.64e-02 GO:0043167 ion binding
1.50 3.00e-02 GO:0003677 DNA binding
2.30 3.55e-02 GO:0019904 protein domain specific binding
6.04 4.41e-02 GO:0008013 beta-catenin binding