Motif ID: GFI1B.p2

Z-value: 0.815


Transcription factors associated with GFI1B.p2:

Gene SymbolEntrez IDGene Name
GFI1B 8328 growth factor independent 1B transcription repressor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GFI1Bchr9_+_1358540970.374.4e-02Click!


Activity profile for motif GFI1B.p2.

activity profile for motif GFI1B.p2


Sorted Z-values histogram for motif GFI1B.p2

Sorted Z-values for motif GFI1B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_70117168 2.978 SOX9
SRY (sex determining region Y)-box 9
chr12_-_28124915 2.563 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr17_+_70117177 2.427 SOX9
SRY (sex determining region Y)-box 9
chr1_-_153085963 2.005 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr3_-_112359547 1.846 CCDC80
coiled-coil domain containing 80
chr3_-_112359565 1.514 CCDC80
coiled-coil domain containing 80
chr3_-_112359660 1.474 CCDC80
coiled-coil domain containing 80
chr3_-_112359863 1.377 CCDC80
coiled-coil domain containing 80
chr2_-_190044330 1.248 NM_000393
COL5A2
collagen, type V, alpha 2
chr1_-_204135420 1.223 NM_000537
REN
renin
chr3_-_112359962 1.171 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr6_-_26216871 1.108 NM_003518
HIST1H2BG
NCALD
histone cluster 1, H2bg
neurocalcin delta
chr2_-_113594325 1.094 NM_000576
IL1B
interleukin 1, beta
chr7_-_113559048 1.081 NM_002711
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr5_+_137203559 1.061 MYOT
myotilin
chr2_-_165424993 1.043 GRB14
growth factor receptor-bound protein 14
chr18_-_24445652 1.028 NM_001650
AQP4
aquaporin 4
chr6_-_144329342 1.028 NM_001080952
NM_001080953
NM_001080954
NM_001080956
NM_002656
NM_006718
PLAGL1





HYMAI
pleiomorphic adenoma gene-like 1





hydatidiform mole associated and imprinted (non-protein coding)
chr5_+_137203544 0.998 NM_001135940
NM_006790
MYOT

myotilin

chr2_+_219472487 0.991 NM_032726
PLCD4
phospholipase C, delta 4
chr2_+_219472618 0.974 PLCD4
phospholipase C, delta 4
chr14_-_24047428 0.965 JPH4
junctophilin 4
chr2_+_219472631 0.932 PLCD4
phospholipase C, delta 4
chr8_-_124544376 0.919 NM_148177
FBXO32
F-box protein 32
chr2_-_113542970 0.907 NM_000575
IL1A
interleukin 1, alpha
chr8_+_67783736 0.853 NM_001136160
C8orf45
chromosome 8 open reading frame 45
chr1_-_17308072 0.843 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr21_-_27512668 0.798 NM_001136016
APP
amyloid beta (A4) precursor protein
chr11_+_18287807 0.785 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr8_+_124194873 0.753 FAM83A
family with sequence similarity 83, member A
chr7_-_56101830 0.740 PSPH
phosphoserine phosphatase
chr12_-_8815479 0.729 MFAP5
microfibrillar associated protein 5
chr7_+_18548899 0.706 NM_001204147
NM_001204148
HDAC9

histone deacetylase 9

chr15_+_40509628 0.700 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr21_-_47648672 0.682 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr21_-_47648715 0.681 NM_001001438
NM_001145436
NM_001145437
NM_002340
LSS



lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)



chr2_+_62900985 0.678 NM_001142615
EHBP1
EH domain binding protein 1
chr3_+_172468469 0.675 ECT2
epithelial cell transforming sequence 2 oncogene
chrX_+_100805415 0.663 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr11_+_19372270 0.650 NM_001111018
NAV2
neuron navigator 2
chr10_+_74653338 0.637 NM_152635
OIT3
oncoprotein induced transcript 3
chrX_+_46696424 0.634 RP2
retinitis pigmentosa 2 (X-linked recessive)
chr19_-_14247400 0.625 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr8_+_27179918 0.625 NM_004103
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr5_-_22853730 0.621 NM_004061
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr2_+_176987412 0.601 NM_014213
HOXD9
homeobox D9
chr4_-_40936640 0.594 APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr14_+_96722546 0.594 NM_000710
BDKRB1
bradykinin receptor B1
chr5_-_22853435 0.588 CDH12
cadherin 12, type 2 (N-cadherin 2)
chr21_+_30517897 0.574 C21orf7
chromosome 21 open reading frame 7
chr3_-_123339423 0.571 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr10_-_129924467 0.553 NM_001145966
NM_002417
MKI67

antigen identified by monoclonal antibody Ki-67

chr22_+_44395090 0.542 NM_001003828
PARVB
parvin, beta
chr17_-_70116928 0.538 FLJ37644
uncharacterized LOC400618
chr19_-_52674895 0.521 NM_001102657
ZNF836
zinc finger protein 836
chr4_+_166248816 0.519 NM_001017369
NM_006745
MSMO1

methylsterol monooxygenase 1

chr1_+_24840800 0.519 NM_001251980
NM_001251982
NM_001251985
RCAN3


RCAN family member 3


chr5_+_14143287 0.517 NM_007118
TRIO
triple functional domain (PTPRF interacting)
chr1_-_179112178 0.514 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr7_+_28475233 0.505 NM_004904
CREB5
cAMP responsive element binding protein 5
chr3_-_123339178 0.497 MYLK
myosin light chain kinase
chr17_-_29648631 0.490 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr8_+_124194751 0.486 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr6_+_43738177 0.462 VEGFA
vascular endothelial growth factor A
chr6_+_43738394 0.460 VEGFA
vascular endothelial growth factor A
chrY_+_14774201 0.449 TTTY15
testis-specific transcript, Y-linked 15 (non-protein coding)
chr5_+_109025135 0.447 NM_002372
MAN2A1
mannosidase, alpha, class 2A, member 1
chr21_-_47648685 0.442 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr3_-_167191808 0.433 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr12_+_18891040 0.421 NM_033328
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr12_-_56756526 0.416 NM_001638
APOF
apolipoprotein F
chr7_+_63773185 0.415 NM_001170905
ZNF736
zinc finger protein 736
chr17_-_56494930 0.408 NM_017763
RNF43
ring finger protein 43
chr6_-_131321868 0.406 NM_001252660
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr15_+_38544119 0.404 SPRED1
sprouty-related, EVH1 domain containing 1
chr15_-_83953465 0.403 NM_001717
BNC1
basonuclin 1
chr3_-_158390266 0.401 NM_020169
LXN
latexin
chr1_-_118472178 0.401 GDAP2
ganglioside induced differentiation associated protein 2
chr8_+_26150731 0.400 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr6_+_31707724 0.399 NM_002441
NM_025259
NM_172165
NM_172166
MSH5-C6orf26
MSH5



MSH5-C6orf26 readthrough (non-protein coding)
mutS homolog 5 (E. coli)



chr6_+_80714389 0.397 TTK
TTK protein kinase
chr3_+_51575595 0.392 NM_015106
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr9_+_96233420 0.391 FAM120A
family with sequence similarity 120A
chr4_-_76928601 0.390 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr8_-_57026540 0.389 NM_005372
MOS
v-mos Moloney murine sarcoma viral oncogene homolog
chr6_+_80714321 0.385 NM_001166691
NM_003318
TTK

TTK protein kinase

chr6_-_22297729 0.380 NM_000948
PRL
prolactin
chr4_+_88529680 0.379 NM_014208
DSPP
dentin sialophosphoprotein
chr18_+_32073343 0.378 DTNA
dystrobrevin, alpha
chr1_+_33283193 0.375 S100PBP
S100P binding protein
chr6_-_41254392 0.373 NM_001242589
NM_001242590
NM_018643
TREM1


triggering receptor expressed on myeloid cells 1


chr13_-_101185944 0.373 NM_033110
A2LD1
AIG2-like domain 1
chr3_+_159557649 0.372 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr12_+_54674531 0.370 HNRNPA1L2
HNRNPA1
heterogeneous nuclear ribonucleoprotein A1-like 2
heterogeneous nuclear ribonucleoprotein A1
chrX_+_57618268 0.359 NM_007157
ZXDB
zinc finger, X-linked, duplicated B
chr3_+_159557745 0.352 SCHIP1
schwannomin interacting protein 1
chr17_-_76183074 0.348 NM_003258
TK1
thymidine kinase 1, soluble
chr5_+_15500288 0.344 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr6_+_12290528 0.342 NM_001168319
NM_001955
EDN1

endothelin 1

chr19_+_19303007 0.331 NM_003721
NM_134440
RFXANK

regulatory factor X-associated ankyrin-containing protein

chr9_-_27297106 0.331 NM_001161585
NM_020641
C9orf11

chromosome 9 open reading frame 11

chr19_-_14247267 0.330 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr8_-_19540093 0.327 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr11_-_69590170 0.327 NM_002007
FGF4
fibroblast growth factor 4
chr5_-_146833150 0.327 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr1_-_27816676 0.324 NM_001201404
NM_006990
WASF2

WAS protein family, member 2

chr18_+_11981421 0.321 NM_014214
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr1_-_242162364 0.319 NM_001004343
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr1_+_24834083 0.319 NM_001251978
RCAN3
RCAN family member 3
chr1_+_168250277 0.317 NM_005149
TBX19
T-box 19
chr1_-_27816542 0.317 WASF2
WAS protein family, member 2
chr3_+_158991035 0.313 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr8_-_93029864 0.312 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_232940637 0.306 NM_019090
KIAA1383
KIAA1383
chr4_-_155511838 0.303 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr6_-_109775423 0.300 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr1_-_27816667 0.300 WASF2
WAS protein family, member 2
chr1_+_232941111 0.300 KIAA1383
KIAA1383
chr5_+_66124603 0.297 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr14_+_21510384 0.295 NM_032572
RNASE7
ribonuclease, RNase A family, 7
chr16_+_15744082 0.294 NM_017668
NDE1
nudE nuclear distribution gene E homolog 1 (A. nidulans)
chr14_-_24047993 0.293 NM_001146028
NM_032452
JPH4

junctophilin 4

chr13_-_46756291 0.286 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chrX_-_21676416 0.286 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr1_+_84647342 0.284 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_+_169418167 0.284 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr10_-_90712510 0.284 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr4_-_82126200 0.283 NM_006259
PRKG2
protein kinase, cGMP-dependent, type II
chr19_-_10628606 0.281 NM_001166215
S1PR5
sphingosine-1-phosphate receptor 5
chrX_+_135278912 0.281 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr18_+_21452981 0.273 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr2_-_51259536 0.272 NM_001135659
NM_004801
NRXN1

neurexin 1

chr17_-_39525873 0.269 NM_002279
KRT33B
keratin 33B
chrX_+_46696346 0.267 NM_006915
RP2
retinitis pigmentosa 2 (X-linked recessive)
chr4_+_110749149 0.265 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr22_-_41682169 0.265 RANGAP1
Ran GTPase activating protein 1
chr12_+_54674478 0.262 NM_002136
NM_031157
HNRNPA1

heterogeneous nuclear ribonucleoprotein A1

chr6_-_26017960 0.262 NM_005325
HIST1H1A
histone cluster 1, H1a
chr9_+_105757592 0.261 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr22_+_19467467 0.261 CDC45
cell division cycle 45 homolog (S. cerevisiae)
chr19_+_16308664 0.255 NM_001130524
NM_032493
AP1M1

adaptor-related protein complex 1, mu 1 subunit

chr22_-_41682187 0.255 NM_002883
RANGAP1
Ran GTPase activating protein 1
chr19_+_4007690 0.255 NM_015897
PIAS4
protein inhibitor of activated STAT, 4
chr11_-_35278749 0.255 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr12_-_371994 0.250 NM_001190997
NM_001243392
NM_016615
SLC6A13


solute carrier family 6 (neurotransmitter transporter, GABA), member 13


chr19_-_54604070 0.249 NM_130771
NM_133168
NM_133169
NM_206818
OSCAR



osteoclast associated, immunoglobulin-like receptor



chr1_+_116654375 0.248 NM_152367
MAB21L3
mab-21-like 3 (C. elegans)
chr2_+_204732509 0.246 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr8_+_32504250 0.245 NM_013959
NRG1
neuregulin 1
chr5_-_59995938 0.242 NM_001145208
NM_018369
DEPDC1B

DEP domain containing 1B

chr3_-_149095333 0.240 TM4SF1
transmembrane 4 L six family member 1
chr19_-_57678855 0.237 NM_001012729
DUXA
double homeobox A
chr18_+_47088400 0.236 NM_006033
LIPG
lipase, endothelial
chr14_-_94759594 0.236 NM_001100607
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr15_-_76304762 0.235 NM_138573
NRG4
neuregulin 4
chr18_+_11981552 0.235 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr17_-_38574042 0.234 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr12_+_57853917 0.234 NM_001160045
NM_001167609
NM_005269
GLI1


GLI family zinc finger 1


chr4_-_76944585 0.234 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr2_+_113033146 0.230 NM_198581
ZC3H6
zinc finger CCCH-type containing 6
chrX_+_15518899 0.227 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr2_+_65216526 0.226 SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr3_+_159943252 0.224 NM_001168214
C3orf80
chromosome 3 open reading frame 80
chr12_-_8815266 0.224 MFAP5
microfibrillar associated protein 5
chr9_+_33624214 0.224 ANXA2P2
annexin A2 pseudogene 2
chr15_+_76629101 0.224 NM_145805
ISL2
ISL LIM homeobox 2
chr1_-_6420719 0.223 NM_181865
ACOT7
acyl-CoA thioesterase 7
chr17_-_79894967 0.219 NM_006907
NM_153824
PYCR1

pyrroline-5-carboxylate reductase 1

chrX_+_69642880 0.213 NM_001171191
NM_001171192
NM_001171193
NM_017711
GDPD2



glycerophosphodiester phosphodiesterase domain containing 2



chr11_-_118135197 0.211 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr4_+_71200670 0.206 NM_033122
CABS1
calcium-binding protein, spermatid-specific 1
chr6_-_138820578 0.202 NM_001144060
NHSL1
NHS-like 1
chr7_+_28452143 0.200 NM_182898
CREB5
cAMP responsive element binding protein 5
chr4_+_1953831 0.200 WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr14_-_94759556 0.200 SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr16_+_56995761 0.199 NM_000078
CETP
cholesteryl ester transfer protein, plasma
chr17_-_56494889 0.199 RNF43
ring finger protein 43
chr1_+_107683548 0.197 NTNG1
netrin G1
chr8_+_6566153 0.197 AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr1_-_151804225 0.196 NM_005060
RORC
RAR-related orphan receptor C
chr6_+_53883713 0.196 NM_138569
MLIP
muscular LMNA-interacting protein
chr7_-_142630819 0.195 NM_019841
TRPV5
transient receptor potential cation channel, subfamily V, member 5
chr16_+_8806825 0.195 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr21_+_35014624 0.194 NM_001001132
NM_003024
ITSN1

intersectin 1 (SH3 domain protein)

chr2_+_168043792 0.190 NM_001199144
NM_001199145
XIRP2

xin actin-binding repeat containing 2

chrX_+_47004609 0.189 NM_001204466
NM_001204467
NM_001204468
NM_005676
NM_152856
RBM10




RNA binding motif protein 10




chr12_-_54673879 0.185 CBX5
chromobox homolog 5
chr9_+_12693385 0.184 NM_000550
TYRP1
tyrosinase-related protein 1
chr1_+_220701523 0.183 MARK1
MAP/microtubule affinity-regulating kinase 1
chr1_-_155939051 0.181 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr12_-_123187842 0.179 NM_177551
HCAR2
hydroxycarboxylic acid receptor 2
chr1_+_101702304 0.179 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr15_+_43477315 0.178 NM_012142
CCNDBP1
cyclin D-type binding-protein 1
chr6_+_57182398 0.177 NM_000947
PRIM2
primase, DNA, polypeptide 2 (58kDa)
chr17_-_9694613 0.176 NM_001105571
NM_001220493
DHRS7C

dehydrogenase/reductase (SDR family) member 7C

chr7_+_137761177 0.176 NM_001190906
NM_001190907
NM_005989
AKR1D1


aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)


chr12_+_6603291 0.175 NM_014865
NCAPD2
non-SMC condensin I complex, subunit D2
chr12_+_96252705 0.175 NM_003095
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr15_+_32933869 0.175 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr4_+_119947816 0.175 SYNPO2
synaptopodin 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.37 4.11e-04 GO:0032501 multicellular organismal process
1.45 1.98e-03 GO:0023052 signaling
1.25 2.45e-03 GO:0065007 biological regulation
1.61 6.57e-03 GO:0048869 cellular developmental process
3.44 8.58e-03 GO:0006874 cellular calcium ion homeostasis
1.60 1.31e-02 GO:0030154 cell differentiation
3.33 1.36e-02 GO:0055074 calcium ion homeostasis
3.33 1.36e-02 GO:0072503 cellular divalent inorganic cation homeostasis
4.05 1.49e-02 GO:0051480 cytosolic calcium ion homeostasis
1.15 1.88e-02 GO:0009987 cellular process
4.22 1.96e-02 GO:0007204 elevation of cytosolic calcium ion concentration
3.21 2.26e-02 GO:0072507 divalent inorganic cation homeostasis
1.39 2.90e-02 GO:0032502 developmental process
1.41 3.12e-02 GO:0007165 signal transduction
1.36 3.56e-02 GO:0051716 cellular response to stimulus
1.85 3.83e-02 GO:0007154 cell communication

Nothing significant found in compartment category.

Nothing significant found in function category.