Motif ID: GGAAGAC

Z-value: 0.665


Mature miRNA associated with seed GGAAGAC:

NamemiRBase Accession
hsa-miR-7 MIMAT0000252



Activity profile for motif GGAAGAC.

activity profile for motif GGAAGAC


Sorted Z-values histogram for motif GGAAGAC

Sorted Z-values for motif GGAAGAC



Network of associatons between targets according to the STRING database.



First level regulatory network of GGAAGAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_72052354 1.365 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr1_-_217262946 1.119 NM_001243506
NM_206594
NM_206595
ESRRG


estrogen-related receptor gamma


chr1_-_217311095 1.068 NM_001134285
ESRRG
estrogen-related receptor gamma
chr14_-_90085325 1.057 NM_001085471
FOXN3
forkhead box N3
chr1_-_216896640 1.040 NM_001243515
NM_001243518
NM_001243519
NM_001438
ESRRG



estrogen-related receptor gamma



chr17_-_56406120 1.027 NM_004758
NM_024418
BZRAP1

benzodiazapine receptor (peripheral) associated protein 1

chr14_-_89883306 0.997 NM_005197
FOXN3
forkhead box N3
chr1_+_61547625 0.976 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr1_+_61542928 0.971 NM_001145511
NFIA
nuclear factor I/A
chr17_+_68165660 0.951 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr1_+_162351519 0.930 NM_001085375
C1orf226
chromosome 1 open reading frame 226
chr19_+_10543110 0.837 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr13_+_115079943 0.817 NM_001164144
NM_001164145
NM_032436
CHAMP1


chromosome alignment maintaining phosphoprotein 1


chr1_+_61547388 0.802 NM_001145512
NFIA
nuclear factor I/A
chr4_+_72204769 0.735 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr19_+_41620336 0.725 NM_000774
CYP2F1
cytochrome P450, family 2, subfamily F, polypeptide 1
chr1_+_118148506 0.700 NM_017709
FAM46C
family with sequence similarity 46, member C
chr19_+_10563581 0.700 NM_006202
PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_-_46598250 0.696 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr19_+_10531128 0.688 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr19_+_10541334 0.638 NM_001111308
PDE4A
phosphodiesterase 4A, cAMP-specific
chr11_+_45868956 0.612 NM_021117
CRY2
cryptochrome 2 (photolyase-like)
chr20_+_5986560 0.612 NM_019095
CRLS1
cardiolipin synthase 1
chr2_+_120189342 0.589 NM_183240
TMEM37
transmembrane protein 37
chr2_+_75185765 0.581 NM_019896
POLE4
polymerase (DNA-directed), epsilon 4 (p12 subunit)
chr11_+_45868668 0.578 NM_001127457
CRY2
cryptochrome 2 (photolyase-like)
chr5_-_111093251 0.575 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr20_-_20693122 0.571 NM_020343
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr5_-_111093030 0.571 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr17_-_47439326 0.557 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr5_-_111092918 0.550 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr5_-_111093792 0.548 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr7_+_75831194 0.540 NM_001110199
SRRM3
serine/arginine repetitive matrix 3
chr20_+_5987897 0.525 NM_001127458
CRLS1
cardiolipin synthase 1
chr1_+_89990396 0.522 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr2_-_55459406 0.522 NM_152385
C2orf63
chromosome 2 open reading frame 63
chr17_-_74137370 0.508 NM_001454
FOXJ1
forkhead box J1
chr17_+_29718641 0.502 NM_032932
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr4_+_129730772 0.496 NM_024900
NM_199320
PHF17

PHD finger protein 17

chr2_-_55459698 0.495 NM_001135598
C2orf63
chromosome 2 open reading frame 63
chr1_-_42921923 0.494 NM_001146192
NM_032257
ZMYND12

zinc finger, MYND-type containing 12

chr5_+_137688270 0.489 NM_016604
KDM3B
lysine (K)-specific demethylase 3B
chr14_-_68066919 0.482 NM_004569
PIGH
phosphatidylinositol glycan anchor biosynthesis, class H
chr21_-_35831856 0.479 NM_001127668
NM_001127669
KCNE1

potassium voltage-gated channel, Isk-related family, member 1

chrX_-_112066353 0.478 NM_001113490
AMOT
angiomotin
chr21_-_35883570 0.474 NM_000219
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr1_+_100598705 0.473 NM_019083
CCDC76
coiled-coil domain containing 76
chr13_-_110438896 0.463 NM_003749
IRS2
insulin receptor substrate 2
chr3_-_52931595 0.459 NM_001198974
NM_198563
TMEM110-MUSTN1
TMEM110
TMEM110-MUSTN1 readthrough
transmembrane protein 110
chr1_+_78956727 0.456 NM_000959
NM_001039585
PTGFR

prostaglandin F receptor (FP)

chr17_+_40985416 0.454 NM_005789
NM_176863
PSME3

proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)

chr20_-_48530275 0.454 NM_001135773
SPATA2
spermatogenesis associated 2
chr21_-_35828038 0.449 NM_001127670
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr5_-_111312522 0.442 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr19_+_51815095 0.438 NM_001101372
IGLON5
IgLON family member 5
chr13_+_27131799 0.406 NM_006646
WASF3
WAS protein family, member 3
chr18_-_53255734 0.402 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chrX_+_16964730 0.391 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr1_+_90024271 0.388 NM_015350
LRRC8B
leucine rich repeat containing 8 family, member B
chr14_-_92414004 0.387 NM_006329
FBLN5
fibulin 5
chrX_+_70752911 0.386 NM_181672
NM_181673
OGT

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)

chr3_-_167098070 0.376 NM_001199202
NM_001199201
NM_024687
ZBBX


zinc finger, B-box domain containing


chr12_-_63328663 0.368 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr15_+_75287829 0.367 NM_001178111
NM_001178112
NM_138967
SCAMP5


secretory carrier membrane protein 5


chr2_-_217560247 0.359 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr10_+_72163860 0.357 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr7_+_66093854 0.356 NM_001167961
NM_153033
KCTD7

potassium channel tetramerisation domain containing 7

chr1_-_115053758 0.355 NM_015906
NM_033020
TRIM33

tripartite motif containing 33

chr16_+_58283819 0.355 NM_001142302
NM_014157
CCDC113

coiled-coil domain containing 113

chr14_-_95786095 0.354 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr2_-_242212244 0.345 NM_001243900
NM_203346
HDLBP

high density lipoprotein binding protein

chr19_-_47617008 0.345 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr6_-_16761600 0.338 NM_000332
NM_001128164
ATXN1

ataxin 1

chr7_+_105603656 0.335 NM_152750
CDHR3
cadherin-related family member 3
chr12_+_122150638 0.335 NM_001080825
TMEM120B
transmembrane protein 120B
chr15_+_99192696 0.330 NM_000875
IGF1R
insulin-like growth factor 1 receptor
chr16_+_66878281 0.328 NM_005182
CA7
carbonic anhydrase VII
chr5_+_131630065 0.319 NM_003059
SLC22A4
solute carrier family 22 (organic cation/ergothioneine transporter), member 4
chr3_-_113415313 0.315 NM_001009899
KIAA2018
KIAA2018
chr5_+_156693051 0.315 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr20_+_51588945 0.310 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chrX_-_112084006 0.308 NM_133265
AMOT
angiomotin
chr1_-_226595796 0.302 NM_001618
PARP1
poly (ADP-ribose) polymerase 1
chr6_-_154677868 0.302 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr19_+_708766 0.302 NM_001040134
NM_002579
PALM

paralemmin

chr5_+_156696351 0.296 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr15_+_82555101 0.296 NM_001008226
FAM154B
family with sequence similarity 154, member B
chr1_+_205538111 0.295 NM_181644
MFSD4
major facilitator superfamily domain containing 4
chr2_-_239148626 0.295 NM_001142853
NM_018645
HES6

hairy and enhancer of split 6 (Drosophila)

chr19_+_41497182 0.292 NM_000767
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr7_-_6098813 0.291 NM_001134335
NM_014413
EIF2AK1

eukaryotic translation initiation factor 2-alpha kinase 1

chr2_+_233498206 0.291 NM_025202
EFHD1
EF-hand domain family, member D1
chr7_-_10979752 0.287 NM_002489
NDUFA4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr20_+_51801821 0.287 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr19_-_2721337 0.285 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr4_+_25658085 0.283 NM_001177999
SLC34A2
solute carrier family 34 (sodium phosphate), member 2
chr6_-_154651214 0.281 NM_001130699
IPCEF1
interaction protein for cytohesin exchange factors 1
chr16_+_57406398 0.277 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr13_+_36050885 0.277 NM_001204197
NBEA
neurobeachin
chr20_-_3149070 0.276 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr1_+_20512577 0.273 NM_152376
UBXN10
UBX domain protein 10
chr16_+_3019341 0.269 NM_152341
PAQR4
progestin and adipoQ receptor family member IV
chr6_-_39082750 0.269 NM_018322
C6orf64
chromosome 6 open reading frame 64
chr10_+_92980322 0.269 NM_032373
PCGF5
polycomb group ring finger 5
chr2_-_7005764 0.265 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr1_+_18807423 0.261 NM_152375
KLHDC7A
kelch domain containing 7A
chr21_-_45759268 0.259 NM_004928
C21orf2
chromosome 21 open reading frame 2
chr16_+_69599868 0.257 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr14_+_74486049 0.257 NM_025057
C14orf45
chromosome 14 open reading frame 45
chr19_+_57702833 0.255 NM_003417
ZNF264
zinc finger protein 264
chr2_-_97535669 0.253 NM_017789
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr17_+_4981721 0.253 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chr17_+_7761063 0.251 NM_144607
CYB5D1
cytochrome b5 domain containing 1
chr16_+_19467771 0.251 NM_024780
TMC5
transmembrane channel-like 5
chr22_-_39548448 0.250 NM_175709
CBX7
chromobox homolog 7
chr17_+_5390212 0.250 NM_024039
MIS12
MIS12, MIND kinetochore complex component, homolog (S. pombe)
chr12_+_133757994 0.250 NM_001165883
NM_001165884
NM_001165885
NM_001165886
NM_001165887
NM_003415
NM_152943
NM_001165881
NM_001165882
ZNF268








zinc finger protein 268








chr9_-_99329092 0.249 NM_001077181
CDC14B
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr16_+_66878840 0.249 NM_001014435
CA7
carbonic anhydrase VII
chrX_+_150565655 0.248 NM_001017980
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr7_+_2557496 0.242 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr8_+_17354562 0.242 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr14_+_58765209 0.241 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr1_+_212738675 0.241 NM_001030287
ATF3
activating transcription factor 3
chr16_-_18937722 0.240 NM_015092
SMG1
smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr21_-_43735705 0.240 NM_003226
TFF3
trefoil factor 3 (intestinal)
chr18_+_9137560 0.239 NM_001204056
ANKRD12
ankyrin repeat domain 12
chr1_+_162467594 0.238 NM_144624
NM_175866
UHMK1

U2AF homology motif (UHM) kinase 1

chr9_-_4300028 0.237 NM_001042413
GLIS3
GLIS family zinc finger 3
chr13_+_35516390 0.236 NM_015678
NBEA
neurobeachin
chr4_+_25657434 0.236 NM_001177998
NM_006424
SLC34A2

solute carrier family 34 (sodium phosphate), member 2

chr15_+_57210823 0.234 NM_003205
NM_207036
NM_207037
NM_207038
TCF12



transcription factor 12



chr10_+_96305521 0.233 NM_018063
HELLS
helicase, lymphoid-specific
chr17_-_9929567 0.231 NM_001130831
GAS7
growth arrest-specific 7
chr1_+_212781969 0.230 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr10_-_94333847 0.229 NM_004969
IDE
insulin-degrading enzyme
chr7_+_2552162 0.227 NM_001166355
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr9_-_4152182 0.226 NM_152629
GLIS3
GLIS family zinc finger 3
chr12_+_65218351 0.226 NM_015279
TBC1D30
TBC1 domain family, member 30
chr8_+_104152876 0.225 NM_001024372
NM_024812
BAALC

brain and acute leukemia, cytoplasmic

chr16_-_12010518 0.225 NM_001130007
GSPT1
G1 to S phase transition 1
chr6_+_84743250 0.223 NM_138409
MRAP2
melanocortin 2 receptor accessory protein 2
chr5_+_149109814 0.220 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr7_-_112430408 0.217 NM_022484
TMEM168
transmembrane protein 168
chr7_+_43966007 0.217 NM_015983
UBE2D4
ubiquitin-conjugating enzyme E2D 4 (putative)
chr15_-_40398286 0.214 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr3_-_88108047 0.214 NM_001008390
NM_003663
CGGBP1

CGG triplet repeat binding protein 1

chr5_+_149151502 0.212 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr1_+_162466963 0.212 NM_001184763
UHMK1
U2AF homology motif (UHM) kinase 1
chr15_-_40398573 0.211 NM_033503
BMF
Bcl2 modifying factor
chr8_+_75896707 0.211 NM_031461
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr17_-_9940004 0.207 NM_201432
GAS7
growth arrest-specific 7
chr13_-_20110884 0.206 NM_001141968
NM_130785
NM_199254
TPTE2


transmembrane phosphoinositide 3-phosphatase and tensin homolog 2


chr5_-_111091947 0.206 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr17_-_10101854 0.205 NM_201433
GAS7
growth arrest-specific 7
chr15_+_43809805 0.204 NM_002373
MAP1A
microtubule-associated protein 1A
chr17_+_42977141 0.203 NM_213607
CCDC103
coiled-coil domain containing 103
chr9_-_99382073 0.202 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr1_+_45965855 0.200 NM_015506
MMACHC
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr20_+_30945988 0.200 NM_001164603
NM_015338
ASXL1

additional sex combs like 1 (Drosophila)

chr8_+_17396285 0.199 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr11_-_119234859 0.197 NM_171997
USP2
ubiquitin specific peptidase 2
chr16_+_19422056 0.196 NM_001105248
NM_001105249
TMC5

transmembrane channel-like 5

chr1_+_183605207 0.195 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr16_-_4166185 0.194 NM_001116
ADCY9
adenylate cyclase 9
chr15_+_44084039 0.194 NM_001018108
NM_001199875
NM_001199876
SERF2


small EDRK-rich factor 2


chr10_-_17244069 0.194 NM_004412
TRDMT1
tRNA aspartic acid methyltransferase 1
chr6_+_90272036 0.192 NM_001242811
ANKRD6
ankyrin repeat domain 6
chr1_+_36348795 0.190 NM_012199
EIF2C1
eukaryotic translation initiation factor 2C, 1
chr20_-_30310597 0.186 NM_001191
NM_138578
BCL2L1

BCL2-like 1

chr2_+_97426571 0.186 NM_020184
CNNM4
cyclin M4
chrX_-_53449610 0.185 NM_006306
SMC1A
structural maintenance of chromosomes 1A
chr19_+_11925077 0.184 NM_152357
ZNF440
zinc finger protein 440
chr6_-_33285718 0.183 NM_001145338
ZBTB22
zinc finger and BTB domain containing 22
chr12_-_50297575 0.180 NM_012306
FAIM2
Fas apoptotic inhibitory molecule 2
chr17_-_4167028 0.180 NM_016376
NM_020740
ANKFY1

ankyrin repeat and FYVE domain containing 1

chr18_+_44526786 0.179 NM_031303
KATNAL2
katanin p60 subunit A-like 2
chr15_-_40401041 0.179 NM_001003940
BMF
Bcl2 modifying factor
chr4_-_23891608 0.177 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr6_-_33285493 0.177 NM_005453
ZBTB22
zinc finger and BTB domain containing 22
chr7_+_138818489 0.177 NM_001144920
NM_001144923
NM_024926
TTC26


tetratricopeptide repeat domain 26


chr15_+_44069272 0.173 NM_001199877
SERF2
small EDRK-rich factor 2
chr10_+_81838417 0.172 NM_025125
FAM213A
family with sequence similarity 213, member A
chr5_-_58334936 0.171 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr14_-_94856926 0.171 NM_001002235
NM_001002236
NM_001127700
NM_001127701
NM_001127702
NM_001127703
NM_001127704
NM_001127705
NM_001127706
NM_001127707
SERPINA1









serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1









chr11_-_70507911 0.170 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr15_+_78556901 0.170 NM_001130182
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr15_+_78558522 0.169 NM_001130183
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr16_+_14013989 0.168 NM_005236
ERCC4
excision repair cross-complementing rodent repair deficiency, complementation group 4
chr14_-_94855120 0.167 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr15_-_54051837 0.165 NM_182758
WDR72
WD repeat domain 72
chr6_-_80247103 0.165 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr5_+_127419407 0.164 NM_001046
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr11_+_101785720 0.163 NM_020802
KIAA1377
KIAA1377
chr1_-_207095198 0.163 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr17_-_33700619 0.163 NM_001104587
NM_001104588
NM_001104589
NM_001104590
NM_152270
SLFN11




schlafen family member 11




chr15_-_68498373 0.162 NM_001031733
NM_033429
CALML4

calmodulin-like 4

chr6_+_90142802 0.161 NM_001242809
NM_001242813
NM_014942
ANKRD6


ankyrin repeat domain 6


chr6_+_138483024 0.161 NM_020340
KIAA1244
KIAA1244
chr20_-_33460558 0.160 NM_178026
GGT7
gamma-glutamyltransferase 7

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.34 1.10e-02 GO:0016567 protein ubiquitination
1.43 1.45e-02 GO:0043412 macromolecule modification
2.11 2.74e-02 GO:0070647 protein modification by small protein conjugation or removal
2.18 5.00e-02 GO:0032446 protein modification by small protein conjugation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 4.22e-03 GO:0005634 nucleus

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.31 1.33e-02 GO:0004842 ubiquitin-protein ligase activity
2.18 3.90e-02 GO:0019787 small conjugating protein ligase activity
2.02 4.30e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds