Motif ID: GLI1..3.p2

Z-value: 2.323


Transcription factors associated with GLI1..3.p2:

Gene SymbolEntrez IDGene Name
GLI1 2735 glioma-associated oncogene homolog 1 (zinc finger protein)
GLI2 2736 GLI-Kruppel family member GLI2
GLI3 2737 GLI-Kruppel family member GLI3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GLI1chr12_+_578539170.761.3e-06Click!
GLI3chr7_-_422766170.641.3e-04Click!
GLI2chr2_+_1215548660.561.2e-03Click!


Activity profile for motif GLI1..3.p2.

activity profile for motif GLI1..3.p2


Sorted Z-values histogram for motif GLI1..3.p2

Sorted Z-values for motif GLI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GLI1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_39873276 11.110 NM_003246
THBS1
thrombospondin 1
chr19_-_41859519 8.536 TGFB1
transforming growth factor, beta 1
chr19_-_51472003 8.371 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr17_-_34122547 7.405 NM_001032278
NM_024302
MMP28

matrix metallopeptidase 28

chr12_-_57634474 7.014 NM_020142
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr1_+_65991357 6.826 NM_001198687
NM_001198688
NM_001198689
LEPR


leptin receptor


chr19_-_41859332 6.665 TGFB1
transforming growth factor, beta 1
chr20_+_62328002 5.945 NM_003823
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr1_+_152881022 5.897 NM_005547
IVL
involucrin
chr5_-_157002739 5.891 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr2_-_26205327 5.886 KIF3C
kinesin family member 3C
chr1_+_150521786 5.813 NM_019032
NM_025008
ADAMTSL4

ADAMTS-like 4

chr20_+_62328068 5.802 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr7_+_100770378 5.675 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr1_+_32042085 5.668 NM_001204414
NM_022164
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr1_-_152386727 5.625 NM_016190
CRNN
cornulin
chr10_-_90712510 5.606 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr12_-_52845862 5.488 NM_005555
KRT6B
keratin 6B
chr1_+_32042122 5.460 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr1_+_32042125 5.259 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr18_+_33877630 5.216 NM_025135
FHOD3
formin homology 2 domain containing 3
chr1_+_45205533 5.173 KIF2C
kinesin family member 2C
chr9_+_35673852 5.166 NM_001216
CA9
carbonic anhydrase IX
chr1_+_45205466 5.158 NM_006845
KIF2C
kinesin family member 2C
chr22_+_31478845 5.113 NM_001207017
SMTN
smoothelin
chr1_+_45205558 5.096 KIF2C
kinesin family member 2C
chr10_+_75936546 5.080 ADK
adenosine kinase
chrX_+_64887534 4.730 MSN
moesin
chr16_+_31483066 4.728 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr19_-_41859830 4.689 NM_000660
TGFB1
transforming growth factor, beta 1
chr4_+_8200918 4.685 NM_018986
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr7_-_24797031 4.642 DFNA5
deafness, autosomal dominant 5
chr19_+_45418063 4.601 APOC1
apolipoprotein C-I
chr17_-_76921076 4.542 TIMP2
TIMP metallopeptidase inhibitor 2
chr4_+_75230856 4.519 NM_001432
EREG
epiregulin
chr2_-_31361284 4.482 GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr19_+_54371150 4.480 MYADM
myeloid-associated differentiation marker
chr19_+_54371125 4.368 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr19_-_51456159 4.367 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr8_+_124194873 4.296 FAM83A
family with sequence similarity 83, member A
chr11_-_123065836 4.259 CLMP
CXADR-like membrane protein
chr6_-_131291480 4.256 NM_001199389
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr19_+_54371170 4.250 MYADM
myeloid-associated differentiation marker
chr19_+_676346 4.232 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chrX_+_64887510 4.215 NM_002444
MSN
moesin
chr9_+_139557378 4.168 NM_016215
EGFL7
EGF-like-domain, multiple 7
chr2_-_31440378 4.159 NM_001145122
CAPN14
calpain 14
chr10_+_75936524 4.122 ADK
adenosine kinase
chr19_-_41858948 4.110 TGFB1
transforming growth factor, beta 1
chr20_+_37554954 4.043 NM_030919
FAM83D
family with sequence similarity 83, member D
chr19_-_19049790 4.038 NM_001145724
HOMER3
homer homolog 3 (Drosophila)
chrX_+_64887593 4.030 MSN
moesin
chr20_+_37555055 4.014 FAM83D
family with sequence similarity 83, member D
chr17_+_39968961 4.011 NM_021939
FKBP10
FK506 binding protein 10, 65 kDa
chr17_-_48262900 3.954 COL1A1
collagen, type I, alpha 1
chr1_+_20915440 3.896 NM_001785
CDA
cytidine deaminase
chr19_-_15343194 3.888 NM_024794
EPHX3
epoxide hydrolase 3
chr1_+_183155173 3.878 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr7_-_24797052 3.854 NM_001127453
DFNA5
deafness, autosomal dominant 5
chr8_+_31497267 3.846 NM_013962
NRG1
neuregulin 1
chr21_-_45079327 3.843 NM_007031
HSF2BP
heat shock transcription factor 2 binding protein
chr20_+_43343884 3.761 NM_003881
WISP2
WNT1 inducible signaling pathway protein 2
chr15_-_74495093 3.716 NM_001199042
NM_022369
STRA6

stimulated by retinoic acid gene 6 homolog (mouse)

chr5_+_150400132 3.707 GPX3
glutathione peroxidase 3 (plasma)
chr19_-_50143350 3.700 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr19_-_51568323 3.696 NM_015596
KLK13
kallikrein-related peptidase 13
chr1_+_183155361 3.682 LAMC2
laminin, gamma 2
chr7_+_130131921 3.661 NM_002402
MEST
mesoderm specific transcript homolog (mouse)
chr10_+_5566923 3.643 NM_005185
CALML3
calmodulin-like 3
chr19_-_41859253 3.595 TGFB1
transforming growth factor, beta 1
chr8_+_37887990 3.589 NM_004095
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
chr6_+_34205029 3.426 HMGA1
high mobility group AT-hook 1
chr16_+_30194925 3.357 CORO1A
coronin, actin binding protein, 1A
chr9_-_113800243 3.350 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr8_-_125740378 3.350 MTSS1
metastasis suppressor 1
chr7_-_24797316 3.340 DFNA5
deafness, autosomal dominant 5
chr19_-_44285407 3.334 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr7_+_143079354 3.323 ZYX
zyxin
chr11_-_72380107 3.316 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr12_-_125348346 3.271 SCARB1
scavenger receptor class B, member 1
chr19_+_11039419 3.257 NM_138358
C19orf52
chromosome 19 open reading frame 52
chr1_+_183155393 3.254 LAMC2
laminin, gamma 2
chr7_-_128045995 3.156 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr11_+_62186506 3.154 NM_003357
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr22_-_28197469 3.123 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr19_-_44285012 3.099 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr10_+_75936443 3.089 ADK
adenosine kinase
chrX_+_152954965 3.007 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chrX_-_106960028 3.000 TSC22D3
TSC22 domain family, member 3
chr10_+_54074037 2.976 NM_012242
DKK1
dickkopf 1 homolog (Xenopus laevis)
chr12_+_57853917 2.969 NM_001160045
NM_001167609
NM_005269
GLI1


GLI family zinc finger 1


chr19_+_38810461 2.956 NM_004823
KCNK6
potassium channel, subfamily K, member 6
chr6_-_133084585 2.953 NM_078488
VNN2
vanin 2
chr11_-_119187811 2.947 NM_006500
MCAM
melanoma cell adhesion molecule
chr16_+_50308020 2.920 ADCY7
adenylate cyclase 7
chr15_-_74494851 2.912 STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr9_+_131644368 2.880 NM_001127245
NM_019594
LRRC8A

leucine rich repeat containing 8 family, member A

chr20_+_33759773 2.875 NM_006404
PROCR
protein C receptor, endothelial
chr7_-_41742666 2.867 NM_002192
INHBA
inhibin, beta A
chr12_-_3862217 2.859 EFCAB4B
EF-hand calcium binding domain 4B
chr19_+_38810540 2.834 KCNK6
potassium channel, subfamily K, member 6
chr11_-_107729492 2.811 SLC35F2
solute carrier family 35, member F2
chr10_+_75936220 2.792 NM_001123
NM_001202449
ADK

adenosine kinase

chr1_+_220701523 2.776 MARK1
MAP/microtubule affinity-regulating kinase 1
chr4_-_103265818 2.775 SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr4_+_75480628 2.752 NM_001657
AREG
amphiregulin
chr1_+_163291722 2.747 NM_031423
NM_145697
NUF2

NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)

chr12_-_125348422 2.722 NM_001082959
NM_005505
SCARB1

scavenger receptor class B, member 1

chr7_+_130131172 2.717 NM_177525
MEST
mesoderm specific transcript homolog (mouse)
chr3_-_48130283 2.710 MAP4
microtubule-associated protein 4
chr16_+_30194730 2.704 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr13_+_111138079 2.657 COL4A2
collagen, type IV, alpha 2
chr10_-_116164514 2.650 NM_001001936
NM_032550
AFAP1L2

actin filament associated protein 1-like 2

chr3_+_136537860 2.650 NM_001097599
NM_001097600
NM_025246
TMEM22


transmembrane protein 22


chrX_-_152938742 2.604 NM_001135740
PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr6_-_46703429 2.571 NM_001168357
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr17_-_41623652 2.562 NM_001079675
ETV4
ets variant 4
chr9_+_131644427 2.551 LRRC8A
leucine rich repeat containing 8 family, member A
chr17_-_39768939 2.550 NM_005557
KRT16
keratin 16
chr10_+_82173574 2.534 NM_001243778
NM_001243782
C10orf58

chromosome 10 open reading frame 58

chr6_+_34205369 2.528 HMGA1
high mobility group AT-hook 1
chr11_+_13690246 2.519 FAR1
fatty acyl CoA reductase 1
chr22_-_19166276 2.519 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr1_+_209859524 2.511 NM_001206741
NM_181755
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr11_+_124933007 2.453 NM_001145290
NM_198277
SLC37A2

solute carrier family 37 (glycerol-3-phosphate transporter), member 2

chr1_-_6420719 2.426 NM_181865
ACOT7
acyl-CoA thioesterase 7
chr7_-_24797557 2.398 NM_001127454
NM_004403
DFNA5

deafness, autosomal dominant 5

chr15_-_75017710 2.389 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr1_-_200589856 2.383 NM_014875
KIF14
kinesin family member 14
chr7_-_23509631 2.366


chr7_-_23509972 2.365 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr20_+_6748744 2.311 NM_001200
BMP2
bone morphogenetic protein 2
chr11_+_9779832 2.309 LOC283104
uncharacterized LOC283104
chr19_+_54372659 2.309 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr8_+_27183062 2.300 NM_173175
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr6_-_105627857 2.290 NM_022361
POPDC3
popeye domain containing 3
chr7_+_44240555 2.290 YKT6
YKT6 v-SNARE homolog (S. cerevisiae)
chr17_-_80009649 2.286 NM_002917
RFNG
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr9_+_131183122 2.285 CERCAM
cerebral endothelial cell adhesion molecule
chr12_-_54778456 2.253 NM_015481
ZNF385A
zinc finger protein 385A
chr19_+_45281125 2.253 NM_001130852
NM_012116
CBLC

Cas-Br-M (murine) ecotropic retroviral transforming sequence c

chr13_+_111137249 2.242 COL4A2
collagen, type IV, alpha 2
chr17_+_60705051 2.235 MRC2
mannose receptor, C type 2
chr17_-_80041166 2.233 FASN
fatty acid synthase
chr12_+_70759974 2.227 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr20_-_60942300 2.218 NM_005560
LAMA5
laminin, alpha 5
chr14_+_54863672 2.208 NM_001130851
NM_005192
CDKN3

cyclin-dependent kinase inhibitor 3

chr16_+_88705000 2.205 NM_013278
IL17C
interleukin 17C
chr6_+_43738757 2.205 VEGFA
vascular endothelial growth factor A
chr20_+_35974458 2.185 NM_198291
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr3_-_52567708 2.182 NM_001134231
NT5DC2
5'-nucleotidase domain containing 2
chr10_-_134145333 2.182 STK32C
serine/threonine kinase 32C
chr20_+_43343523 2.165 WISP2
WNT1 inducible signaling pathway protein 2
chr5_+_92920592 2.160 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr6_+_47666288 2.159 NM_153838
GPR115
G protein-coupled receptor 115
chr4_-_164394885 2.148 NM_032136
TKTL2
transketolase-like 2
chr8_+_27183047 2.146 PTK2B
PTK2B protein tyrosine kinase 2 beta
chr12_+_53491448 2.139 IGFBP6
insulin-like growth factor binding protein 6
chr17_+_57970486 2.131 RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr12_-_54813002 2.120 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr4_+_8582216 2.117 NM_080819
GPR78
G protein-coupled receptor 78
chr22_-_19166296 2.107 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr13_-_25745620 2.106 FAM123A
family with sequence similarity 123A
chr5_+_157158322 2.105 NM_017872
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr20_+_42984338 2.104 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr11_+_124933197 2.098 SLC37A2
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr19_+_45417576 2.097 APOC1
apolipoprotein C-I
chr1_+_203595929 2.088 ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr10_-_116164222 2.065 AFAP1L2
actin filament associated protein 1-like 2
chr17_+_4854383 2.065 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr17_-_76921205 2.057 TIMP2
TIMP metallopeptidase inhibitor 2
chr22_-_19165872 2.050 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr8_-_144654921 2.048 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chr7_-_44105162 2.036 NM_000290
PGAM2
phosphoglycerate mutase 2 (muscle)
chr1_+_203595897 2.029 NM_001001396
NM_001684
ATP2B4

ATPase, Ca++ transporting, plasma membrane 4

chr13_-_99229117 2.025 STK24
serine/threonine kinase 24
chr2_+_174219537 2.025 NM_031942
NM_145810
CDCA7

cell division cycle associated 7

chr12_+_47610244 2.022 FAM113B
family with sequence similarity 113, member B
chr7_-_100425035 2.022 NM_004444
EPHB4
EPH receptor B4
chr9_-_34458477 2.010 NM_001184940
NM_001184941
NM_001184942
NM_001184943
NM_001184945
NM_147202
C9orf25





chromosome 9 open reading frame 25





chr20_+_43344005 2.004 WISP2
WNT1 inducible signaling pathway protein 2
chr22_+_38035683 2.001 NM_018957
SH3BP1
SH3-domain binding protein 1
chr10_-_3827418 1.995 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr19_+_35491225 1.986 NM_001136199
NM_020895
GRAMD1A

GRAM domain containing 1A

chr11_-_627172 1.981 NM_021920
SCT
secretin
chr6_+_151561653 1.978 AKAP12
A kinase (PRKA) anchor protein 12
chr3_-_48130633 1.976 NM_001134364
NM_002375
NM_030885
MAP4


microtubule-associated protein 4


chr6_-_111894897 1.968 NM_001164282
TRAF3IP2
TRAF3 interacting protein 2
chr6_+_35995583 1.967 MAPK14
mitogen-activated protein kinase 14
chr3_-_139258531 1.957 NM_001130992
NM_001130993
NM_002899
RBP1


retinol binding protein 1, cellular


chr16_+_55543044 1.956 LPCAT2
lysophosphatidylcholine acyltransferase 2
chr20_-_6103860 1.941 FERMT1
fermitin family member 1
chr13_-_99229037 1.931 STK24
serine/threonine kinase 24
chr22_-_19166133 1.928 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr19_+_6531009 1.925 NM_003811
TNFSF9
tumor necrosis factor (ligand) superfamily, member 9
chr1_+_38158129 1.923 NM_018101
CDCA8
cell division cycle associated 8
chr7_-_92465929 1.914 NM_001145306
CDK6
cyclin-dependent kinase 6
chr13_-_20767100 1.913 NM_004004
GJB2
gap junction protein, beta 2, 26kDa
chr7_+_44240569 1.894 NM_006555
YKT6
YKT6 v-SNARE homolog (S. cerevisiae)
chr16_+_27325244 1.889 NM_000418
NM_001008699
IL4R

interleukin 4 receptor


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.41 1.83e-06 GO:0023051 regulation of signaling
1.38 1.83e-06 GO:0048583 regulation of response to stimulus
1.24 3.56e-06 GO:0023052 signaling
1.42 1.10e-05 GO:0009966 regulation of signal transduction
1.40 2.47e-05 GO:0009653 anatomical structure morphogenesis
1.25 2.74e-05 GO:0048856 anatomical structure development
2.37 4.49e-05 GO:0034330 cell junction organization
1.65 4.70e-05 GO:0042060 wound healing
1.46 9.25e-05 GO:0010646 regulation of cell communication
1.26 1.83e-04 GO:0048518 positive regulation of biological process
1.12 2.17e-04 GO:0065007 biological regulation
1.21 4.46e-04 GO:0032502 developmental process
1.22 7.77e-04 GO:0007165 signal transduction
1.08 8.54e-04 GO:0009987 cellular process
2.28 1.27e-03 GO:0034329 cell junction assembly
1.19 1.44e-03 GO:0051716 cellular response to stimulus
1.13 1.52e-03 GO:0050794 regulation of cellular process
1.24 1.52e-03 GO:0048731 system development
1.26 1.53e-03 GO:0048522 positive regulation of cellular process
1.12 1.57e-03 GO:0050789 regulation of biological process
1.28 1.63e-03 GO:0048869 cellular developmental process
1.28 1.82e-03 GO:0030154 cell differentiation
1.45 1.90e-03 GO:0009611 response to wounding
1.82 2.33e-03 GO:0051270 regulation of cellular component movement
2.11 2.73e-03 GO:0051272 positive regulation of cellular component movement
1.13 3.77e-03 GO:0050896 response to stimulus
1.80 4.34e-03 GO:0040012 regulation of locomotion
1.59 7.60e-03 GO:0007596 blood coagulation
1.59 7.60e-03 GO:0050817 coagulation
1.24 8.21e-03 GO:0048519 negative regulation of biological process
1.58 1.03e-02 GO:0007599 hemostasis
1.56 1.40e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.62 1.42e-02 GO:0007409 axonogenesis
1.23 1.45e-02 GO:0006950 response to stress
1.52 1.58e-02 GO:0050878 regulation of body fluid levels
2.03 1.82e-02 GO:0040017 positive regulation of locomotion
1.60 1.82e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
2.05 1.85e-02 GO:0030335 positive regulation of cell migration
2.05 1.85e-02 GO:2000147 positive regulation of cell motility
1.72 1.95e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.59 2.05e-02 GO:0048812 neuron projection morphogenesis
1.56 2.21e-02 GO:0031175 neuron projection development
1.25 2.34e-02 GO:0048523 negative regulation of cellular process
1.78 2.35e-02 GO:0030334 regulation of cell migration
1.38 2.52e-02 GO:0032879 regulation of localization
1.36 2.60e-02 GO:0051246 regulation of protein metabolic process
1.37 3.19e-02 GO:0007154 cell communication
1.39 3.30e-02 GO:0048468 cell development
1.76 3.51e-02 GO:2000145 regulation of cell motility
1.54 3.55e-02 GO:0000904 cell morphogenesis involved in differentiation
1.41 3.56e-02 GO:0051128 regulation of cellular component organization
1.67 3.57e-02 GO:0007411 axon guidance
1.48 3.63e-02 GO:0032989 cellular component morphogenesis
1.71 4.69e-02 GO:0071900 regulation of protein serine/threonine kinase activity

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.61 1.86e-05 GO:0030054 cell junction
1.11 1.87e-04 GO:0005737 cytoplasm
1.40 2.46e-04 GO:0000267 cell fraction
1.95 1.97e-03 GO:0031252 cell leading edge
2.04 2.30e-03 GO:0005912 adherens junction
1.24 2.74e-03 GO:0044459 plasma membrane part
2.33 4.93e-03 GO:0001726 ruffle
2.25 5.55e-03 GO:0005925 focal adhesion
2.21 5.78e-03 GO:0005924 cell-substrate adherens junction
1.39 1.19e-02 GO:0005624 membrane fraction
1.23 1.31e-02 GO:0005829 cytosol
2.13 1.32e-02 GO:0030055 cell-substrate junction
1.89 1.42e-02 GO:0070161 anchoring junction
1.37 1.77e-02 GO:0005626 insoluble fraction
1.11 3.07e-02 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 4.94e-13 GO:0005515 protein binding
1.06 1.59e-02 GO:0005488 binding