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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: HIC1.p2

Z-value: 1.774

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr13_+_110959592	6.956	NM_001846	COL4A2	collagen, type IV, alpha 2
chr2_-_224903933	6.343	NM_001136528 NM_006216	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr2_-_224903324	6.145	NM_001136530	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr17_-_76921076	5.957		TIMP2	TIMP metallopeptidase inhibitor 2
chr6_+_34204928	5.360		HMGA1	high mobility group AT-hook 1
chr10_+_102106958	5.340		SCD	stearoyl-CoA desaturase (delta-9-desaturase)
chr1_-_20812271	5.132		CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr2_+_238536183	5.119	NM_001137550	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chrX_+_135229536	4.909	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr18_-_28681885	4.678	NM_004949 NM_024422	DSC2	desmocollin 2
chr19_-_15343194	4.676	NM_024794	EPHX3	epoxide hydrolase 3
chr18_-_21242592	4.574	NM_173505	ANKRD29	ankyrin repeat domain 29
chr6_+_34205029	4.550		HMGA1	high mobility group AT-hook 1
chr19_-_41859519	4.467		TGFB1	transforming growth factor, beta 1
chr17_-_76921205	4.433		TIMP2	TIMP metallopeptidase inhibitor 2
chr11_+_94822937	4.219	NM_015036	ENDOD1	endonuclease domain containing 1
chr2_-_27718098	4.192	NM_022823	FNDC4	fibronectin type III domain containing 4
chr9_-_72287097	4.129	NM_001163	APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1
chr19_-_41859830	4.115	NM_000660	TGFB1	transforming growth factor, beta 1
chr10_+_102107001	3.860		SCD	stearoyl-CoA desaturase (delta-9-desaturase)
chr2_+_11886739	3.798	NM_145693	LPIN1	lipin 1
chr8_-_23261591	3.622		LOXL2	lysyl oxidase-like 2
chr10_+_102106771	3.616	NM_005063	SCD	stearoyl-CoA desaturase (delta-9-desaturase)
chr8_-_23261626	3.600		LOXL2	lysyl oxidase-like 2
chr6_-_112194430	3.568		FYN	FYN oncogene related to SRC, FGR, YES
chr2_+_102314162	3.468	NM_001242560 NM_004834 NM_145686 NM_001242559 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr2_-_235405692	3.438	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr7_-_24797316	3.397		DFNA5	deafness, autosomal dominant 5
chr6_+_34204690	3.393		HMGA1	high mobility group AT-hook 1
chr2_-_27718059	3.381		FNDC4	fibronectin type III domain containing 4
chr12_-_99038705	3.358		IKBIP	IKBKB interacting protein
chr8_-_23261632	3.271		LOXL2	lysyl oxidase-like 2
chr20_-_23030141	3.237	NM_000361	THBD	thrombomodulin
chr18_+_33877630	3.224	NM_025135	FHOD3	formin homology 2 domain containing 3
chr16_+_31483066	3.211	NM_001042454 NM_001164719	TGFB1I1	transforming growth factor beta 1 induced transcript 1
chr6_-_131384387	3.207	NM_001135554 NM_001135555 NM_001199388 NM_001431	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr1_+_10270680	3.196	NM_015074 NM_183416	KIF1B	kinesin family member 1B
chr2_-_1748240	3.186		PXDN	peroxidasin homolog (Drosophila)
chr7_-_24797031	3.140		DFNA5	deafness, autosomal dominant 5
chr14_+_65171149	3.112	NM_015549	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr12_+_96588000	3.110	NM_005230	ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)
chr14_-_105487421	3.081	NM_017955 NM_145701	CDCA4	cell division cycle associated 4
chr10_+_11784355	3.078	NM_024693	ECHDC3	enoyl CoA hydratase domain containing 3
chr17_+_15848230	3.076	NM_000676	ADORA2B	adenosine A2b receptor
chr6_-_4135701	3.070	NM_001166010 NM_006117 NM_206836	ECI2	enoyl-CoA delta isomerase 2
chr12_-_47473424	3.050	NM_001143668 NM_181847	AMIGO2	adhesion molecule with Ig-like domain 2
chr12_-_122231554	3.048	NM_019034	RHOF	ras homolog gene family, member F (in filopodia)
chr15_-_83953465	3.029	NM_001717	BNC1	basonuclin 1
chr7_-_24797052	3.015	NM_001127453	DFNA5	deafness, autosomal dominant 5
chr7_+_5632435	3.009	NM_003088	FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr1_-_8086347	2.999		ERRFI1	ERBB receptor feedback inhibitor 1
chr22_+_33197744	2.998		TIMP3	TIMP metallopeptidase inhibitor 3
chr19_+_35646006	2.964		FXYD5	FXYD domain containing ion transport regulator 5
chr16_+_2570322	2.959	NM_001145815 NM_015944	AMDHD2	amidohydrolase domain containing 2
chr17_-_80009649	2.931	NM_002917	RFNG	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr3_-_52567809	2.928		NT5DC2	5'-nucleotidase domain containing 2
chr18_+_21269528	2.902	NM_001127717 NM_198129	LAMA3	laminin, alpha 3
chr14_-_105487365	2.889		CDCA4	cell division cycle associated 4
chr2_+_241375235	2.883		GPC1	glypican 1
chr17_-_76921453	2.879	NM_003255	TIMP2	TIMP metallopeptidase inhibitor 2
chr19_-_41859253	2.879		TGFB1	transforming growth factor, beta 1
chr7_+_5632453	2.863		FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr6_-_131384321	2.856		EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr22_+_33197678	2.850		TIMP3	TIMP metallopeptidase inhibitor 3
chr7_+_128578246	2.848	NM_032643	IRF5	interferon regulatory factor 5
chr19_-_41859332	2.816		TGFB1	transforming growth factor, beta 1
chr1_+_230202966	2.808		GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr19_+_35645640	2.789	NM_144779 NM_001164605	FXYD5	FXYD domain containing ion transport regulator 5
chr14_-_53162370	2.784		ERO1L	ERO1-like (S. cerevisiae)
chr8_-_23261675	2.752	NM_002318	LOXL2	lysyl oxidase-like 2
chr7_+_128577990	2.684	NM_001098629 NM_001098630 NM_001242452	IRF5	interferon regulatory factor 5
chr12_+_130647002	2.675	NM_007197	FZD10	frizzled family receptor 10
chr2_+_239756672	2.633	NM_057179	TWIST2	twist homolog 2 (Drosophila)
chr16_-_85784628	2.599	NM_206967	C16orf74	chromosome 16 open reading frame 74
chr1_-_8086392	2.578	NM_018948	ERRFI1	ERBB receptor feedback inhibitor 1
chr6_+_159590428	2.573	NM_032532	FNDC1	fibronectin type III domain containing 1
chr18_+_21269404	2.568		LAMA3	laminin, alpha 3
chr17_-_74581881	2.536		ST6GALNAC2	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr1_+_230202928	2.526	NM_004481	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr6_-_30654978	2.515		PPP1R18	protein phosphatase 1, regulatory subunit 18
chr19_+_16187047	2.514	NM_003290	TPM4	tropomyosin 4
chr1_-_113498828	2.502	NM_003051	SLC16A1	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr1_-_6479880	2.488	NM_019089	HES2	hairy and enhancer of split 2 (Drosophila)
chr16_+_58497548	2.477	NM_020465	NDRG4	NDRG family member 4
chr1_-_20812727	2.465	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr7_-_28220146	2.465		JAZF1	JAZF zinc finger 1
chr6_+_34205369	2.455		HMGA1	high mobility group AT-hook 1
chrX_-_153602998	2.433	NM_001110556 NM_001456	FLNA	filamin A, alpha
chr10_+_17271341	2.426		VIM	vimentin
chr20_-_5591487	2.421	NM_019593	GPCPD1	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr2_-_10220321	2.412	NM_001037160	CYS1	cystin 1
chr5_-_171881355	2.400		SH3PXD2B	SH3 and PX domains 2B
chr11_-_2162340	2.396	NM_001127598	IGF2	insulin-like growth factor 2 (somatomedin A)
chr14_-_53162418	2.395	NM_014584	ERO1L	ERO1-like (S. cerevisiae)
chr16_+_58497628	2.391		NDRG4	NDRG family member 4
chr19_+_54926721	2.387		TTYH1	tweety homolog 1 (Drosophila)
chr14_+_55034633	2.370		SAMD4A	sterile alpha motif domain containing 4A
chr12_-_69326946	2.363	NM_001005502 NM_198320	CPM	carboxypeptidase M
chr10_-_43762366	2.353	NM_145313	RASGEF1A	RasGEF domain family, member 1A
chr21_-_44846927	2.348	NM_173354	SIK1	salt-inducible kinase 1
chr7_-_50860665	2.341		GRB10	growth factor receptor-bound protein 10
chr12_+_70759974	2.330	NM_014505	KCNMB4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr8_-_125740378	2.328		MTSS1	metastasis suppressor 1
chr10_+_76871345	2.327	NM_001174156 NM_144660	SAMD8	sterile alpha motif domain containing 8
chr10_+_102107074	2.324		SCD	stearoyl-CoA desaturase (delta-9-desaturase)
chr18_+_56338783	2.312		MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1
chr7_+_155089614	2.285		INSIG1	insulin induced gene 1
chr7_+_130131921	2.282	NM_002402	MEST	mesoderm specific transcript homolog (mouse)
chr12_+_96588254	2.273		ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)
chr12_-_124018066	2.264	NM_178314	RILPL1	Rab interacting lysosomal protein-like 1
chr12_-_124018428	2.255		RILPL1	Rab interacting lysosomal protein-like 1
chr19_+_531737	2.252		CDC34	cell division cycle 34 homolog (S. cerevisiae)
chr17_-_74581934	2.252		ST6GALNAC2	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr4_-_57522469	2.250	NM_001145459 NM_139211	HOPX	HOP homeobox
chr2_+_23608297	2.236	NM_052920	KLHL29	kelch-like 29 (Drosophila)
chr15_-_73661141	2.231		HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr17_-_80056104	2.228	NM_004104	FASN	fatty acid synthase
chr11_+_33061291	2.228		TCP11L1	t-complex 11 (mouse)-like 1
chr2_-_31361284	2.225		GALNT14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr6_+_37137882	2.223	NM_001243186 NM_002648	PIM1	pim-1 oncogene
chr17_+_30813928	2.207	NM_003885	CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr3_+_136537860	2.207	NM_001097599 NM_001097600 NM_025246	TMEM22	transmembrane protein 22
chr1_-_85358851	2.205	NM_012152	LPAR3	lysophosphatidic acid receptor 3
chr5_+_92920592	2.198		NR2F1 NR2F2	nuclear receptor subfamily 2, group F, member 1 nuclear receptor subfamily 2, group F, member 2
chr3_-_52567708	2.197	NM_001134231	NT5DC2	5'-nucleotidase domain containing 2
chr22_+_37956404	2.196	NM_152243	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1
chr14_-_105487413	2.194		CDCA4	cell division cycle associated 4
chr7_-_1199822	2.190	NM_182491	ZFAND2A	zinc finger, AN1-type domain 2A
chr2_+_173420873	2.188		PDK1	pyruvate dehydrogenase kinase, isozyme 1
chr2_-_1748285	2.186	NM_012293	PXDN	peroxidasin homolog (Drosophila)
chr3_-_52090090	2.181	NM_001947	DUSP7	dual specificity phosphatase 7
chr8_-_145050896	2.162	NM_000445	PLEC	plectin
chr7_-_50861114	2.161	NM_001001555	GRB10	growth factor receptor-bound protein 10
chr15_+_90744506	2.157	NM_198925	SEMA4B	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr7_-_128045995	2.150	NM_001142573 NM_001142574 NM_001142575	IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1
chr19_+_16187306	2.142		TPM4	tropomyosin 4
chr16_-_58231641	2.142	NM_001896	CSNK2A2	casein kinase 2, alpha prime polypeptide
chr1_+_182992329	2.136	NM_002293	LAMC1	laminin, gamma 1 (formerly LAMB2)
chr3_-_53290099	2.128	NM_001064 NM_001135055	TKT	transketolase
chr22_+_46692637	2.114	NM_016426	GTSE1	G-2 and S-phase expressed 1
chrX_-_109561427	2.113		AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr4_-_174450529	2.113		HAND2	heart and neural crest derivatives expressed 2
chr18_-_28681429	2.110		DSC2	desmocollin 2
chr10_+_102107256	2.110
chr17_+_15848422	2.099		ADORA2B	adenosine A2b receptor
chr10_+_112257624	2.099	NM_004419	DUSP5	dual specificity phosphatase 5
chr1_-_236030170	2.094
chr13_-_40177304	2.083		LHFP	lipoma HMGIC fusion partner
chr2_+_208576446	2.077		CCNYL1	cyclin Y-like 1
chr14_+_105155724	2.064	NM_001031714 NM_022489 NM_032714	INF2	inverted formin, FH2 and WH2 domain containing
chr7_+_45614179	2.043		ADCY1	adenylate cyclase 1 (brain)
chr11_-_12030882	2.043	NM_013253	DKK3	dickkopf 3 homolog (Xenopus laevis)
chr1_+_220701523	2.037		MARK1	MAP/microtubule affinity-regulating kinase 1
chr7_-_1199785	2.036		ZFAND2A	zinc finger, AN1-type domain 2A
chr3_+_50192420	2.017		SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr7_-_1199813	2.016		ZFAND2A	zinc finger, AN1-type domain 2A
chr7_-_752083	2.008		PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta
chr12_-_123635284	2.007		PITPNM2	phosphatidylinositol transfer protein, membrane-associated 2
chr14_-_75422466	2.005	NM_001207012 NM_002632	PGF	placental growth factor
chr4_+_1873035	2.004	NM_001042424	WHSC1	Wolf-Hirschhorn syndrome candidate 1
chrX_-_8700132	1.996		KAL1	Kallmann syndrome 1 sequence
chr11_+_94501503	1.983	NM_130847	AMOTL1	angiomotin like 1
chr22_+_50609159	1.976	NM_001160300 NM_052839	PANX2	pannexin 2
chr6_-_53213699	1.968		ELOVL5	ELOVL fatty acid elongase 5
chr13_-_110959441	1.963	NM_001845	COL4A1	collagen, type IV, alpha 1
chr7_+_40174594	1.963		C7orf10	chromosome 7 open reading frame 10
chr14_-_53162198	1.960		ERO1L	ERO1-like (S. cerevisiae)
chr1_-_21044202	1.956	NM_001122819 NM_020816	KIF17	kinesin family member 17
chr8_+_86376130	1.950	NM_000067	CA2	carbonic anhydrase II
chr20_+_61340165	1.941	NM_002531	NTSR1	neurotensin receptor 1 (high affinity)
chr5_+_38845959	1.939	NM_001168355	OSMR	oncostatin M receptor
chr8_+_145734445	1.938	NM_138431	MFSD3	major facilitator superfamily domain containing 3
chrX_-_153602928	1.931		FLNA	filamin A, alpha
chr4_+_1723233	1.928		TACC3	transforming, acidic coiled-coil containing protein 3
chr22_-_37915209	1.927	NM_014550	CARD10	caspase recruitment domain family, member 10
chr2_+_9346909	1.927		ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr9_+_137218324	1.918		RXRA	retinoid X receptor, alpha
chr22_-_26986071	1.905	NM_003595	TPST2	tyrosylprotein sulfotransferase 2
chr16_-_88851371	1.894	NM_001142864	PIEZO1	piezo-type mechanosensitive ion channel component 1
chr12_+_53491448	1.894		IGFBP6	insulin-like growth factor binding protein 6
chr2_+_9346876	1.886	NM_001135191 NM_003887	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr19_+_2096930	1.877		IZUMO4	IZUMO family member 4
chr14_-_91282760	1.877	NM_001010854	TTC7B	tetratricopeptide repeat domain 7B
chr6_+_163835668	1.869	NM_006775 NM_206853 NM_206854 NM_206855	QKI	QKI, KH domain containing, RNA binding
chr9_+_124461365	1.867		DAB2IP	DAB2 interacting protein
chr6_-_53213747	1.863	NM_001242828 NM_001242830 NM_001242831 NM_021814	ELOVL5	ELOVL fatty acid elongase 5
chrX_+_21958714	1.860	NM_004595	SMS	spermine synthase
chr7_-_98741375	1.859		SMURF1	SMAD specific E3 ubiquitin protein ligase 1
chr16_+_66638530	1.857	NM_181553	CMTM3	CKLF-like MARVEL transmembrane domain containing 3
chr6_+_160769365	1.854	NM_021977	SLC22A3	solute carrier family 22 (extraneuronal monoamine transporter), member 3
chr2_+_9614636	1.838	NM_001039613	IAH1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
chr17_+_16945766	1.836	NM_015134 NM_201274	MPRIP	myosin phosphatase Rho interacting protein
chr10_-_3827418	1.832	NM_001160124 NM_001160125 NM_001300	KLF6	Kruppel-like factor 6
chr4_-_177713664	1.828	NM_005429	VEGFC	vascular endothelial growth factor C
chr22_-_26986041	1.826		TPST2	tyrosylprotein sulfotransferase 2
chr7_+_27135672	1.825		HOTAIRM1	HOXA transcript antisense RNA, myeloid-specific 1 (non-protein coding)
chr15_+_68570038	1.824	NM_015322	FEM1B	fem-1 homolog b (C. elegans)
chr11_-_12030838	1.815		DKK3	dickkopf 3 homolog (Xenopus laevis)
chr9_-_123639462	1.814		PHF19	PHD finger protein 19
chr1_-_6557448	1.813		PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.13	1.98e-30	GO:0009987	cellular process
1.17	6.09e-18	GO:0050794	regulation of cellular process
1.15	3.22e-17	GO:0065007	biological regulation
1.15	6.77e-17	GO:0050789	regulation of biological process
1.40	7.55e-16	GO:0023051	regulation of signaling
1.41	2.41e-14	GO:0009966	regulation of signal transduction
1.40	4.04e-14	GO:0007399	nervous system development
1.23	9.41e-14	GO:0032502	developmental process
1.51	1.01e-13	GO:0022008	neurogenesis
1.32	1.09e-12	GO:0030154	cell differentiation
1.51	1.19e-12	GO:0048699	generation of neurons
1.22	2.50e-12	GO:0023052	signaling
1.29	4.01e-12	GO:0048519	negative regulation of biological process
1.30	6.49e-12	GO:0048869	cellular developmental process
1.22	7.20e-12	GO:0051179	localization
1.22	1.57e-11	GO:0007275	multicellular organismal development
1.29	2.44e-11	GO:0048523	negative regulation of cellular process
1.36	4.58e-11	GO:0009653	anatomical structure morphogenesis
1.23	6.66e-11	GO:0048856	anatomical structure development
1.22	7.85e-11	GO:0007165	signal transduction
1.63	8.99e-11	GO:0000904	cell morphogenesis involved in differentiation
1.24	1.65e-10	GO:0048731	system development
1.22	2.31e-10	GO:0016043	cellular component organization
1.36	6.64e-10	GO:0035556	intracellular signal transduction
1.65	7.03e-10	GO:0048667	cell morphogenesis involved in neuron differentiation
1.64	9.47e-10	GO:0048812	neuron projection morphogenesis
1.19	1.12e-09	GO:0051716	cellular response to stimulus
1.14	2.53e-09	GO:0044238	primary metabolic process
1.64	4.00e-09	GO:0007409	axonogenesis
1.20	5.90e-09	GO:0071840	cellular component organization or biogenesis
1.28	8.15e-09	GO:0048583	regulation of response to stimulus
1.23	9.30e-09	GO:0071842	cellular component organization at cellular level
1.13	9.51e-09	GO:0044237	cellular metabolic process
1.57	1.93e-08	GO:0031175	neuron projection development
1.53	2.40e-08	GO:0048666	neuron development
1.21	3.07e-08	GO:0051234	establishment of localization
1.51	3.30e-08	GO:0000902	cell morphogenesis
1.47	4.72e-08	GO:0030182	neuron differentiation
1.68	5.43e-08	GO:0007411	axon guidance
1.40	7.23e-08	GO:0048468	cell development
1.55	7.40e-08	GO:0032990	cell part morphogenesis
1.37	7.57e-08	GO:0010646	regulation of cell communication
1.62	7.57e-08	GO:0007264	small GTPase mediated signal transduction
1.12	7.69e-08	GO:0008152	metabolic process
1.22	8.57e-08	GO:0071841	cellular component organization or biogenesis at cellular level
1.21	9.77e-08	GO:0006810	transport
1.54	1.17e-07	GO:0048858	cell projection morphogenesis
1.23	1.33e-07	GO:0048522	positive regulation of cellular process
1.48	1.41e-07	GO:0032989	cellular component morphogenesis
1.41	3.43e-07	GO:0051128	regulation of cellular component organization
1.21	3.90e-07	GO:0048518	positive regulation of biological process
1.98	9.44e-06	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.43	1.07e-05	GO:0030030	cell projection organization
1.14	1.43e-05	GO:0044260	cellular macromolecule metabolic process
1.96	1.44e-05	GO:0022604	regulation of cell morphogenesis
1.13	1.56e-05	GO:0043170	macromolecule metabolic process
1.33	1.95e-05	GO:0032268	regulation of cellular protein metabolic process
1.44	1.96e-05	GO:0042060	wound healing
1.29	1.97e-05	GO:0033036	macromolecule localization
1.24	2.37e-05	GO:0006464	protein modification process
1.36	2.65e-05	GO:0040011	locomotion
1.21	2.91e-05	GO:0042221	response to chemical stimulus
1.38	2.92e-05	GO:0016192	vesicle-mediated transport
1.31	3.54e-05	GO:0051246	regulation of protein metabolic process
1.34	3.60e-05	GO:0050793	regulation of developmental process
1.33	3.82e-05	GO:0032879	regulation of localization
1.60	3.88e-05	GO:0022603	regulation of anatomical structure morphogenesis
1.59	3.92e-05	GO:0060284	regulation of cell development
1.41	3.92e-05	GO:0007167	enzyme linked receptor protein signaling pathway
1.40	4.09e-05	GO:0045595	regulation of cell differentiation
1.46	4.52e-05	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.15	5.59e-05	GO:0019222	regulation of metabolic process
1.69	7.32e-05	GO:0048011	nerve growth factor receptor signaling pathway
1.65	1.12e-04	GO:0050767	regulation of neurogenesis
1.22	1.45e-04	GO:0043412	macromolecule modification
1.20	2.14e-04	GO:0065008	regulation of biological quality
1.15	3.25e-04	GO:0031323	regulation of cellular metabolic process
1.15	3.95e-04	GO:0080090	regulation of primary metabolic process
1.58	4.17e-04	GO:0051960	regulation of nervous system development
1.43	4.91e-04	GO:0007599	hemostasis
1.43	5.06e-04	GO:0007596	blood coagulation
1.43	5.06e-04	GO:0050817	coagulation
1.56	5.23e-04	GO:0051270	regulation of cellular component movement
1.22	6.01e-04	GO:0007166	cell surface receptor linked signaling pathway
1.88	6.84e-04	GO:0007265	Ras protein signal transduction
1.28	6.85e-04	GO:0008104	protein localization
1.42	8.16e-04	GO:0048585	negative regulation of response to stimulus
1.25	1.29e-03	GO:0051641	cellular localization
1.24	1.29e-03	GO:0065009	regulation of molecular function
1.33	1.29e-03	GO:0031399	regulation of protein modification process
1.39	1.36e-03	GO:0050878	regulation of body fluid levels
1.65	1.51e-03	GO:0045664	regulation of neuron differentiation
1.45	1.82e-03	GO:0009968	negative regulation of signal transduction
1.40	2.04e-03	GO:0006935	chemotaxis
1.40	2.04e-03	GO:0042330	taxis
1.43	2.38e-03	GO:0010648	negative regulation of cell communication
1.64	2.53e-03	GO:0044087	regulation of cellular component biogenesis
1.39	2.83e-03	GO:0023056	positive regulation of signaling
1.41	3.15e-03	GO:0045859	regulation of protein kinase activity
1.42	3.45e-03	GO:0023057	negative regulation of signaling
1.25	3.98e-03	GO:0031325	positive regulation of cellular metabolic process
1.14	4.12e-03	GO:0060255	regulation of macromolecule metabolic process
1.87	4.44e-03	GO:0032956	regulation of actin cytoskeleton organization
1.96	4.54e-03	GO:0060828	regulation of canonical Wnt receptor signaling pathway
1.40	5.05e-03	GO:0007010	cytoskeleton organization
1.45	5.19e-03	GO:0090066	regulation of anatomical structure size
1.51	5.97e-03	GO:0040012	regulation of locomotion
1.31	6.07e-03	GO:2000026	regulation of multicellular organismal development
1.27	7.60e-03	GO:0009605	response to external stimulus
1.37	7.83e-03	GO:0010647	positive regulation of cell communication
1.21	8.23e-03	GO:0006996	organelle organization
1.53	8.35e-03	GO:0030334	regulation of cell migration
1.38	9.71e-03	GO:0019226	transmission of nerve impulse
1.38	9.71e-03	GO:0035637	multicellular organismal signaling
1.34	1.16e-02	GO:0051726	regulation of cell cycle
1.23	1.20e-02	GO:0009893	positive regulation of metabolic process
1.32	1.21e-02	GO:0009719	response to endogenous stimulus
1.26	1.31e-02	GO:0007049	cell cycle
1.65	1.31e-02	GO:0051493	regulation of cytoskeleton organization
1.82	1.32e-02	GO:0032970	regulation of actin filament-based process
1.75	1.42e-02	GO:0010975	regulation of neuron projection development
1.33	1.46e-02	GO:0001932	regulation of protein phosphorylation
1.14	1.49e-02	GO:0019538	protein metabolic process
1.41	1.52e-02	GO:0016477	cell migration
1.51	1.58e-02	GO:2000145	regulation of cell motility
1.42	1.61e-02	GO:0010627	regulation of intracellular protein kinase cascade
1.27	1.62e-02	GO:0010605	negative regulation of macromolecule metabolic process
1.32	1.75e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
2.00	1.93e-02	GO:0050770	regulation of axonogenesis
1.67	1.96e-02	GO:0031344	regulation of cell projection organization
1.22	2.01e-02	GO:0051239	regulation of multicellular organismal process
1.48	2.07e-02	GO:0001944	vasculature development
1.36	2.28e-02	GO:0009967	positive regulation of signal transduction
1.31	2.36e-02	GO:0042325	regulation of phosphorylation
1.25	2.42e-02	GO:0006793	phosphorus metabolic process
1.25	2.42e-02	GO:0006796	phosphate metabolic process
1.52	2.58e-02	GO:0046578	regulation of Ras protein signal transduction
1.26	2.66e-02	GO:0009892	negative regulation of metabolic process
1.32	2.87e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.34	2.94e-02	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.50	2.96e-02	GO:0045596	negative regulation of cell differentiation
1.91	3.01e-02	GO:0030178	negative regulation of Wnt receptor signaling pathway
1.36	3.06e-02	GO:0043549	regulation of kinase activity
1.30	3.13e-02	GO:0009890	negative regulation of biosynthetic process
1.34	3.19e-02	GO:0006928	cellular component movement
1.27	3.71e-02	GO:0016265	death
1.44	3.92e-02	GO:0032535	regulation of cellular component size
1.66	4.27e-02	GO:0034330	cell junction organization
1.27	4.30e-02	GO:0045184	establishment of protein localization
1.94	4.52e-02	GO:0010721	negative regulation of cell development
1.35	4.62e-02	GO:0051338	regulation of transferase activity
1.26	4.98e-02	GO:0008219	cell death

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.17	1.39e-29	GO:0005737	cytoplasm
1.11	5.21e-25	GO:0005622	intracellular
1.11	8.40e-24	GO:0044424	intracellular part
1.17	7.19e-17	GO:0044444	cytoplasmic part
1.31	2.59e-13	GO:0005829	cytosol
1.09	1.92e-09	GO:0043229	intracellular organelle
1.09	2.56e-09	GO:0043226	organelle
1.88	2.88e-08	GO:0031252	cell leading edge
1.93	1.93e-07	GO:0005912	adherens junction
1.04	2.67e-07	GO:0044464	cell part
1.04	2.90e-07	GO:0005623	cell
1.09	3.47e-07	GO:0043231	intracellular membrane-bounded organelle
1.09	3.76e-07	GO:0043227	membrane-bounded organelle
1.86	5.08e-07	GO:0070161	anchoring junction
1.44	9.78e-07	GO:0030054	cell junction
1.37	1.06e-06	GO:0005626	insoluble fraction
1.34	2.02e-05	GO:0005624	membrane fraction
1.29	2.40e-05	GO:0000267	cell fraction
1.24	2.75e-05	GO:0012505	endomembrane system
1.97	5.07e-05	GO:0005925	focal adhesion
1.29	1.54e-04	GO:0005794	Golgi apparatus
1.18	2.08e-04	GO:0044459	plasma membrane part
1.45	2.42e-04	GO:0043005	neuron projection
1.30	2.46e-04	GO:0042995	cell projection
2.15	2.52e-04	GO:0031256	leading edge membrane
1.88	3.75e-04	GO:0005924	cell-substrate adherens junction
1.10	3.76e-04	GO:0044446	intracellular organelle part
1.84	6.00e-04	GO:0030055	cell-substrate junction
1.21	6.55e-04	GO:0005856	cytoskeleton
1.10	9.96e-04	GO:0044422	organelle part
1.35	1.10e-03	GO:0044431	Golgi apparatus part
1.49	1.43e-03	GO:0015629	actin cytoskeleton
1.54	1.96e-03	GO:0016323	basolateral plasma membrane
1.29	4.01e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
1.14	5.27e-03	GO:0043234	protein complex
1.28	5.35e-03	GO:0031410	cytoplasmic vesicle
1.28	8.14e-03	GO:0031988	membrane-bounded vesicle
1.57	1.09e-02	GO:0030424	axon
1.26	1.14e-02	GO:0031982	vesicle
1.82	1.47e-02	GO:0030027	lamellipodium
2.93	1.52e-02	GO:0032589	neuron projection membrane
1.09	1.95e-02	GO:0005634	nucleus
1.74	2.04e-02	GO:0019717	synaptosome
1.76	3.09e-02	GO:0001726	ruffle
2.03	3.13e-02	GO:0005905	coated pit
1.63	3.50e-02	GO:0031253	cell projection membrane
1.31	4.88e-02	GO:0000139	Golgi membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.18	8.42e-25	GO:0005515	protein binding
1.09	1.21e-17	GO:0005488	binding
1.59	4.25e-09	GO:0019904	protein domain specific binding
1.45	4.54e-06	GO:0008092	cytoskeletal protein binding
1.11	9.60e-05	GO:0003824	catalytic activity
1.22	1.81e-04	GO:0016740	transferase activity
1.53	2.67e-04	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.42	2.67e-04	GO:0060589	nucleoside-triphosphatase regulator activity
1.42	3.03e-04	GO:0030695	GTPase regulator activity
1.55	3.66e-04	GO:0016881	acid-amino acid ligase activity
1.58	6.05e-04	GO:0019787	small conjugating protein ligase activity
1.46	2.69e-03	GO:0003779	actin binding
1.55	3.91e-03	GO:0004842	ubiquitin-protein ligase activity
1.77	5.91e-03	GO:0017124	SH3 domain binding
1.43	8.54e-03	GO:0042578	phosphoric ester hydrolase activity
1.17	1.08e-02	GO:0032553	ribonucleotide binding
1.17	1.08e-02	GO:0032555	purine ribonucleotide binding
1.17	1.69e-02	GO:0017076	purine nucleotide binding
1.48	1.92e-02	GO:0016791	phosphatase activity
1.25	1.92e-02	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.60	2.10e-02	GO:0004721	phosphoprotein phosphatase activity
1.17	2.18e-02	GO:0035639	purine ribonucleoside triphosphate binding
1.15	3.17e-02	GO:0000166	nucleotide binding
1.24	3.26e-02	GO:0030234	enzyme regulator activity
1.27	3.53e-02	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.26	3.54e-02	GO:0019899	enzyme binding
1.77	4.56e-02	GO:0005088	Ras guanyl-nucleotide exchange factor activity
1.25	4.98e-02	GO:0016301	kinase activity