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• Activity deltas table
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Motif ID: IKZF1.p2

Z-value: 1.239

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_-_23261626	4.139		LOXL2	lysyl oxidase-like 2
chr8_-_23261591	3.962		LOXL2	lysyl oxidase-like 2
chr8_-_23261632	3.857		LOXL2	lysyl oxidase-like 2
chr16_+_23690234	3.765		PLK1	polo-like kinase 1
chr19_-_51456159	3.708	NM_001077491 NM_001077492 NM_012427	KLK5	kallikrein-related peptidase 5
chr16_+_23690212	3.533		PLK1	polo-like kinase 1
chr2_-_113594325	3.140	NM_000576	IL1B	interleukin 1, beta
chr8_-_23261675	3.038	NM_002318	LOXL2	lysyl oxidase-like 2
chr16_+_23690190	2.627		PLK1	polo-like kinase 1
chr1_+_32042122	2.357		TINAGL1	tubulointerstitial nephritis antigen-like 1
chr1_+_32042085	2.343	NM_001204414 NM_022164	TINAGL1	tubulointerstitial nephritis antigen-like 1
chr1_+_32042125	2.220		TINAGL1	tubulointerstitial nephritis antigen-like 1
chr16_+_23690160	2.207		PLK1	polo-like kinase 1
chr16_+_23690191	2.175	NM_005030	PLK1	polo-like kinase 1
chr22_+_19467413	2.131	NM_001178010 NM_001178011 NM_003504	CDC45	cell division cycle 45 homolog (S. cerevisiae)
chr8_+_37887990	2.079	NM_004095	EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1
chr22_+_19467467	2.053		CDC45	cell division cycle 45 homolog (S. cerevisiae)
chr19_+_54371150	2.017		MYADM	myeloid-associated differentiation marker
chr19_+_54371125	2.006	NM_001020819 NM_138373	MYADM	myeloid-associated differentiation marker
chr8_+_48873533	2.002		MCM4	minichromosome maintenance complex component 4
chr12_-_58160823	1.984	NM_000785	CYP27B1	cytochrome P450, family 27, subfamily B, polypeptide 1
chr14_-_24732344	1.975	NM_000359	TGM1	transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)
chr12_+_41086189	1.897	NM_001843 NM_175038	CNTN1	contactin 1
chr15_-_73661141	1.857		HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr1_+_32043745	1.846	NM_001204415	TINAGL1	tubulointerstitial nephritis antigen-like 1
chr1_-_152386727	1.742	NM_016190	CRNN	cornulin
chr6_+_31126114	1.680	NM_001077511 NM_007109	TCF19	transcription factor 19
chr20_-_23030141	1.673	NM_000361	THBD	thrombomodulin
chr3_+_127317271	1.672		MCM2	minichromosome maintenance complex component 2
chr10_-_5541401	1.636	NM_017422	CALML5	calmodulin-like 5
chr2_-_190044330	1.630	NM_000393	COL5A2	collagen, type V, alpha 2
chr17_-_7493389	1.620	NM_006942	SOX15	SRY (sex determining region Y)-box 15
chr7_-_148581403	1.598	NM_001203247 NM_001203248 NM_004456 NM_152998	EZH2	enhancer of zeste homolog 2 (Drosophila)
chr7_-_148581379	1.569		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr7_-_148581377	1.566		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr3_+_127317274	1.559		MCM2	minichromosome maintenance complex component 2
chr19_-_51845377	1.537	NM_001163922	VSIG10L	V-set and immunoglobulin domain containing 10 like
chr19_-_19052032	1.528	NM_004838	HOMER3	homer homolog 3 (Drosophila)
chr19_+_54371170	1.525		MYADM	myeloid-associated differentiation marker
chr6_+_34204928	1.501		HMGA1	high mobility group AT-hook 1
chr19_-_36019194	1.498	NM_001166034 NM_001166035 NM_198538	SBSN	suprabasin
chr17_-_41322211	1.482		BRCA1	breast cancer 1, early onset
chr19_-_19051899	1.452		HOMER3	homer homolog 3 (Drosophila)
chr11_+_62649160	1.437		SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr7_+_48128939	1.435		UPP1	uridine phosphorylase 1
chr17_-_59940669	1.412	NM_032043	BRIP1	BRCA1 interacting protein C-terminal helicase 1
chr15_+_63336274	1.400		TPM1	tropomyosin 1 (alpha)
chr7_-_148581359	1.390		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr12_-_6960406	1.341	NM_031299	CDCA3	cell division cycle associated 3
chr7_-_99698916	1.308		MCM7	minichromosome maintenance complex component 7
chr7_-_148581297	1.237		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr11_-_10715032	1.223	NM_001100167	MRVI1	murine retrovirus integration site 1 homolog
chr1_-_54303933	1.212		TMEM48	transmembrane protein 48
chr1_+_26606212	1.211	NM_031286	SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3
chr10_+_135340865	1.174	NM_000773	CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1
chr16_+_29690464	1.171		QPRT	quinolinate phosphoribosyltransferase
chr1_+_183155173	1.164	NM_005562 NM_018891	LAMC2	laminin, gamma 2
chr8_-_125740650	1.154	NM_014751	MTSS1	metastasis suppressor 1
chr11_-_10715503	1.140	NM_001100163 NM_001206880 NM_001206881 NM_130385	MRVI1	murine retrovirus integration site 1 homolog
chr10_+_102891060	1.137	NM_001195517 NM_005521	TLX1	T-cell leukemia homeobox 1
chr4_-_120987890	1.135	NM_002358	MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)
chr14_+_65171243	1.129		PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr4_-_47983430	1.119	NM_001142564	CNGA1	cyclic nucleotide gated channel alpha 1
chr19_-_51504799	1.118	NM_007196 NM_144505 NM_144506 NM_144507	KLK8	kallikrein-related peptidase 8
chr8_+_48873446	1.102		MCM4	minichromosome maintenance complex component 4
chr15_+_71839540	1.091		THSD4	thrombospondin, type I, domain containing 4
chr3_+_121796695	1.090	NM_006889 NM_176892	CD86	CD86 molecule
chr1_-_28520379	1.082	NM_001164721 NM_001164722	PTAFR	platelet-activating factor receptor
chr15_+_75182351	1.081	NM_002435	MPI	mannose phosphate isomerase
chr17_-_76921205	1.076		TIMP2	TIMP metallopeptidase inhibitor 2
chr21_-_34960937	1.076	NM_017613	DONSON	downstream neighbor of SON
chr18_-_28681885	1.057	NM_004949 NM_024422	DSC2	desmocollin 2
chr2_-_55646946	1.049	NM_001135597 NM_018084	CCDC88A	coiled-coil domain containing 88A
chr2_-_193059249	1.033		TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr12_-_76425375	1.033	NM_007350	PHLDA1	pleckstrin homology-like domain, family A, member 1
chr4_-_74864296	1.031	NM_002994	CXCL5	chemokine (C-X-C motif) ligand 5
chr18_+_2571509	1.023	NM_006101	NDC80	NDC80 kinetochore complex component homolog (S. cerevisiae)
chr9_+_131644780	1.018	NM_001127244	LRRC8A	leucine rich repeat containing 8 family, member A
chr21_+_37507209	1.004	NM_001236	CBR3	carbonyl reductase 3
chr1_-_26680620	1.002	NM_001039775	AIM1L	absent in melanoma 1-like
chr19_-_11688508	0.992	NM_001611	ACP5	acid phosphatase 5, tartrate resistant
chr15_+_67358161	0.989		SMAD3	SMAD family member 3
chr17_+_38474513	0.984		RARA	retinoic acid receptor, alpha
chr4_+_140222668	0.983	NM_057175	NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr2_-_172290435	0.972		METTL8	methyltransferase like 8
chr14_+_65171149	0.971	NM_015549	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr17_+_48712115	0.953	NM_001144070 NM_003786	ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr19_-_36001336	0.949	NM_001126059	DMKN	dermokine
chr17_-_27401216	0.938		TIAF1	TGFB1-induced anti-apoptotic factor 1
chr9_+_112887780	0.915	NM_001136562	AKAP2	A kinase (PRKA) anchor protein 2
chr2_-_43453146	0.912		ZFP36L2	zinc finger protein 36, C3H type-like 2
chr18_+_56338818	0.907		MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1
chr20_+_44441334	0.903		UBE2C	ubiquitin-conjugating enzyme E2C
chr17_-_27401590	0.899		TIAF1	TGFB1-induced anti-apoptotic factor 1
chr15_+_67358194	0.896	NM_005902	SMAD3	SMAD family member 3
chr11_+_72980938	0.892	NM_176798	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6
chr16_+_29690328	0.890	NM_014298	QPRT	quinolinate phosphoribosyltransferase
chr18_+_56338678	0.890		MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1
chr10_+_75936546	0.882		ADK	adenosine kinase
chr1_+_90098643	0.880	NM_032270	LRRC8C	leucine rich repeat containing 8 family, member C
chr18_+_2571587	0.876		NDC80	NDC80 kinetochore complex component homolog (S. cerevisiae)
chr6_+_31126734	0.869		TCF19	transcription factor 19
chr4_-_159092509	0.868		FAM198B	family with sequence similarity 198, member B
chr1_+_203020310	0.867	NM_015053	PPFIA4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr3_+_44803280	0.854		KIF15	kinesin family member 15
chr10_-_21786205	0.851	NM_001010911	C10orf114	chromosome 10 open reading frame 114
chr7_+_89783688	0.846	NM_012449	STEAP1	six transmembrane epithelial antigen of the prostate 1
chr7_+_87505543	0.845	NM_006716	DBF4	DBF4 homolog (S. cerevisiae)
chr6_+_31126340	0.845		TCF19	transcription factor 19
chr8_+_124194751	0.837	NM_032899 NM_207006	FAM83A	family with sequence similarity 83, member A
chr11_+_3666357	0.833	NM_004314	ART1	ADP-ribosyltransferase 1
chr18_+_56338783	0.832		MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1
chr10_+_75936524	0.827		ADK	adenosine kinase
chr16_+_71392637	0.821		CALB2	calbindin 2
chr22_+_31477231	0.811	NM_006932 NM_134269 NM_134270	SMTN	smoothelin
chr15_+_67418053	0.807	NM_001145102	SMAD3	SMAD family member 3
chr16_+_71392615	0.802	NM_001740 NM_007088	CALB2	calbindin 2
chr5_-_131563481	0.798	NM_001017974 NM_001142598 NM_001142599	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II
chr10_-_21786186	0.782		C10orf114	chromosome 10 open reading frame 114
chr7_-_99699426	0.777	NM_005916	MCM7	minichromosome maintenance complex component 7
chr3_+_160118346	0.776	NM_005496	SMC4	structural maintenance of chromosomes 4
chr7_-_99698278	0.775	NM_182776	MCM7	minichromosome maintenance complex component 7
chr7_+_36429388	0.773	NM_018685	ANLN	anillin, actin binding protein
chr14_-_69446038	0.773	NM_001102 NM_001130004 NM_001130005	ACTN1	actinin, alpha 1
chr5_-_16936290	0.770		MYO10	myosin X
chr11_+_67195886	0.759	NM_003952	RPS6KB2	ribosomal protein S6 kinase, 70kDa, polypeptide 2
chr9_+_90112419	0.755		DAPK1	death-associated protein kinase 1
chr2_+_9983570	0.755	NM_005680	TAF1B	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
chr8_+_48873510	0.755		MCM4	minichromosome maintenance complex component 4
chr5_-_150521200	0.753	NM_001193544	ANXA6	annexin A6
chr3_-_156272909	0.752	NM_007107	SSR3	signal sequence receptor, gamma (translocon-associated protein gamma)
chr8_+_26435920	0.745	NM_001244604	DPYSL2	dihydropyrimidinase-like 2
chr5_-_149669187	0.740		CAMK2A	calcium/calmodulin-dependent protein kinase II alpha
chr3_+_44803208	0.739	NM_020242	KIF15	kinesin family member 15
chr5_+_36152221	0.737		SKP2	S-phase kinase-associated protein 2 (p45)
chr2_+_54785453	0.737	NM_178313	SPTBN1	spectrin, beta, non-erythrocytic 1
chr20_+_44441247	0.732	NM_007019 NM_181799 NM_181800 NM_181802 NM_181803	UBE2C	ubiquitin-conjugating enzyme E2C
chr12_+_57920425	0.731		MBD6	methyl-CpG binding domain protein 6
chr8_+_22224786	0.730		SLC39A14	solute carrier family 39 (zinc transporter), member 14
chr15_+_66679107	0.729	NM_002755	MAP2K1	mitogen-activated protein kinase kinase 1
chr19_-_41934634	0.723	NM_198540	B3GNT8	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr7_-_99698993	0.716		MCM7	minichromosome maintenance complex component 7
chr6_-_2903461	0.715	NM_004155	SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr12_-_76425207	0.710		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr7_-_99699030	0.708		MCM7	minichromosome maintenance complex component 7
chr7_-_92747269	0.707		SAMD9	sterile alpha motif domain containing 9
chr17_+_7517263	0.705		SHBG	sex hormone-binding globulin
chr10_+_75936220	0.704	NM_001123 NM_001202449	ADK	adenosine kinase
chr5_-_136834887	0.704	NM_004598	SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr2_-_24307179	0.691	NM_001206802	TP53I3	tumor protein p53 inducible protein 3
chr9_+_90112754	0.690	NM_004938	DAPK1	death-associated protein kinase 1
chr17_+_38474544	0.687		RARA	retinoic acid receptor, alpha
chr2_-_72374919	0.683	NM_019885	CYP26B1	cytochrome P450, family 26, subfamily B, polypeptide 1
chr21_+_27011766	0.681		JAM2	junctional adhesion molecule 2
chr5_+_36152142	0.679	NM_001243120 NM_005983 NM_032637	SKP2	S-phase kinase-associated protein 2 (p45)
chr10_+_75936443	0.677		ADK	adenosine kinase
chr11_+_64126616	0.674	NM_001006944 NM_003942	RPS6KA4	ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr8_+_26435339	0.672	NM_001386	DPYSL2	dihydropyrimidinase-like 2
chr19_-_1513187	0.671	NM_213604	ADAMTSL5	ADAMTS-like 5
chr1_-_50489489	0.669		AGBL4	ATP/GTP binding protein-like 4
chr12_+_15475190	0.667	NM_002848 NM_030667	PTPRO	protein tyrosine phosphatase, receptor type, O
chr1_-_54304107	0.665	NM_001168551 NM_018087	TMEM48	transmembrane protein 48
chr19_+_45582469	0.661	NM_001007270 NM_001007269 NM_024707	GEMIN7	gem (nuclear organelle) associated protein 7
chr2_-_177502658	0.659		LOC375295	uncharacterized LOC375295
chr11_-_125366048	0.657	NM_005103 NM_022549	FEZ1	fasciculation and elongation protein zeta 1 (zygin I)
chr4_+_166248816	0.646	NM_001017369 NM_006745	MSMO1	methylsterol monooxygenase 1
chr19_+_46801632	0.646	NM_022462 NM_152796	HIF3A	hypoxia inducible factor 3, alpha subunit
chr22_+_38142245	0.641		TRIOBP	TRIO and F-actin binding protein
chr4_-_159956332	0.640	NM_152543	C4orf45	chromosome 4 open reading frame 45
chr3_-_156272868	0.638		SSR3	signal sequence receptor, gamma (translocon-associated protein gamma)
chr3_-_150966901	0.633	NM_001081455	P2RY14	purinergic receptor P2Y, G-protein coupled, 14
chr16_+_31483066	0.632	NM_001042454 NM_001164719	TGFB1I1	transforming growth factor beta 1 induced transcript 1
chr2_+_17721983	0.629		VSNL1	visinin-like 1
chr12_+_55413728	0.625	NM_021191	NEUROD4	neurogenic differentiation 4
chr12_+_66218141	0.622	NM_003483 NM_003484	HMGA2	high mobility group AT-hook 2
chr17_-_76921453	0.620	NM_003255	TIMP2	TIMP metallopeptidase inhibitor 2
chr3_-_138665981	0.618	NM_023067	FOXL2	forkhead box L2
chr14_-_69354900	0.616		ACTN1	actinin, alpha 1
chrX_+_131157231	0.615	NM_001042453 NM_016542	MST4	serine/threonine protein kinase MST4
chr8_+_22224758	0.612	NM_001128431 NM_001135154 NM_015359	SLC39A14	solute carrier family 39 (zinc transporter), member 14
chr2_+_238536183	0.611	NM_001137550	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr16_+_46723577	0.611		ORC6 PPA2	origin recognition complex, subunit 6 pyrophosphatase (inorganic) 2
chr16_-_3068161	0.609	NM_021195	CLDN6	claudin 6
chr1_-_6545521	0.606		PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr22_-_32555200	0.606	NM_001010859	C22orf42	chromosome 22 open reading frame 42
chr22_-_31536339	0.606	NM_015715	PLA2G3	phospholipase A2, group III
chr1_+_35247838	0.605	NM_001005752	GJB3	gap junction protein, beta 3, 31kDa
chr1_-_161207879	0.605	NM_001077469 NM_001077470 NM_001077471 NM_001077472 NM_001077473 NM_001077474 NM_001077475 NM_001077476 NM_001077477 NM_001077478 NM_001077479 NM_001077480 NM_001077481 NM_001077482 NM_005122	NR1I3	nuclear receptor subfamily 1, group I, member 3
chr16_-_87903028	0.604	NM_003486	SLC7A5	solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr17_+_39969205	0.601		FKBP10	FK506 binding protein 10, 65 kDa
chr14_-_48144156	0.598	NM_001113498	MDGA2	MAM domain containing glycosylphosphatidylinositol anchor 2
chr12_-_47473424	0.597	NM_001143668 NM_181847	AMIGO2	adhesion molecule with Ig-like domain 2
chr7_-_126892304	0.596	NM_001127323	GRM8	glutamate receptor, metabotropic 8
chr11_+_76571902	0.589	NM_018367	ACER3	alkaline ceramidase 3
chr19_+_4910339	0.589	NM_013282	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr2_-_25141855	0.588	NM_004036	ADCY3	adenylate cyclase 3
chr2_+_173940441	0.588		ZAK	sterile alpha motif and leucine zipper containing kinase AZK
chr6_+_20404033	0.586	NM_001243076	E2F3	E2F transcription factor 3
chr17_+_38474472	0.583	NM_001145301 NM_001145302	RARA	retinoic acid receptor, alpha
chr3_-_183735617	0.583	NM_001023587 NM_005688	ABCC5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.13	2.35e-10	GO:0009987	cellular process
1.29	2.40e-05	GO:0034641	cellular nitrogen compound metabolic process
1.27	6.77e-05	GO:0006807	nitrogen compound metabolic process
1.16	5.32e-04	GO:0044237	cellular metabolic process
1.28	8.44e-04	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.54	4.65e-03	GO:0007155	cell adhesion
1.54	4.65e-03	GO:0022610	biological adhesion
1.19	1.19e-02	GO:0051716	cellular response to stimulus
1.14	1.53e-02	GO:0044238	primary metabolic process
1.35	2.43e-02	GO:0009966	regulation of signal transduction
1.30	2.80e-02	GO:0048583	regulation of response to stimulus
1.25	3.01e-02	GO:0006950	response to stress
1.12	3.82e-02	GO:0008152	metabolic process
1.19	3.84e-02	GO:0023052	signaling
1.43	4.54e-02	GO:0009611	response to wounding
1.26	4.94e-02	GO:0090304	nucleic acid metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.32	1.47e-04	GO:0005829	cytosol
1.10	8.01e-03	GO:0005737	cytoplasm
1.13	2.50e-02	GO:0044444	cytoplasmic part

Nothing significant found in function category.