Motif ID: JUN.p2

Z-value: 1.238


Transcription factors associated with JUN.p2:

Gene SymbolEntrez IDGene Name
JUN 3725 jun oncogene
JUNB 3726 jun B proto-oncogene
JUND 3727 jun D proto-oncogene

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
JUNBchr19_+_129022950.622.3e-04Click!
JUNDchr19_-_183924130.487.6e-03Click!
JUNchr1_-_59249687-0.374.5e-02Click!


Activity profile for motif JUN.p2.

activity profile for motif JUN.p2


Sorted Z-values histogram for motif JUN.p2

Sorted Z-values for motif JUN.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of JUN.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_68086633 8.861 ARG2
arginase, type II
chr21_-_44846927 7.068 NM_173354
SIK1
salt-inducible kinase 1
chr19_+_16187266 6.745 TPM4
tropomyosin 4
chr4_+_75480628 6.440 NM_001657
AREG
amphiregulin
chr14_+_68086655 6.414 ARG2
arginase, type II
chr4_+_75310852 6.177 NM_001657
AREG
amphiregulin
chr2_-_216300770 6.107 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr19_+_16187306 5.935 TPM4
tropomyosin 4
chr19_+_16187315 5.848 TPM4
tropomyosin 4
chr20_+_34203746 5.664 NM_003116
SPAG4
sperm associated antigen 4
chr7_+_5632435 5.070 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr14_+_68086570 4.752 NM_001172
ARG2
arginase, type II
chr11_-_61584451 4.608 NM_013402
FADS1
fatty acid desaturase 1
chr7_+_5632453 4.538 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr1_-_205391180 4.152 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr19_-_52227220 3.855 NM_001523
HAS1
hyaluronan synthase 1
chr14_-_94443065 3.797 NM_001202429
ASB2
ankyrin repeat and SOCS box containing 2
chr12_+_110011499 3.686 NM_000431
NM_001114185
MVK

mevalonate kinase

chr1_-_20812727 3.654 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr2_-_192015706 3.523 STAT4
signal transducer and activator of transcription 4
chr17_+_41476351 3.461 NM_001661
ARL4D
ADP-ribosylation factor-like 4D
chr15_-_91537724 3.393 NM_003981
NM_199413
NM_199414
PRC1


protein regulator of cytokinesis 1


chr20_+_56285213 3.381


chr2_+_238536183 3.292 NM_001137550
LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr1_+_152956563 3.202 NM_001199828
NM_005987
SPRR1A

small proline-rich protein 1A

chr19_+_16187047 3.164 NM_003290
TPM4
tropomyosin 4
chr19_+_36024313 3.156 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr2_-_192015733 3.039 STAT4
signal transducer and activator of transcription 4
chr9_+_34990266 3.034 NM_001135005
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr11_-_61584228 3.004 FADS1
fatty acid desaturase 1
chr6_-_53213699 2.991 ELOVL5
ELOVL fatty acid elongase 5
chr21_-_45079327 2.983 NM_007031
HSF2BP
heat shock transcription factor 2 binding protein
chr20_-_56284945 2.746 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr16_-_79634610 2.687 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr9_+_34989637 2.674 NM_001135004
NM_012266
DNAJB5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr19_+_17666381 2.595 GLT25D1
glycosyltransferase 25 domain containing 1
chr4_-_104119475 2.571 NM_001813
CENPE
centromere protein E, 312kDa
chr5_+_162887516 2.562 NM_001142556
NM_001142557
NM_012484
NM_012485
HMMR



hyaluronan-mediated motility receptor (RHAMM)



chr2_+_28615695 2.545 FOSL2
FOS-like antigen 2
chr1_+_17531619 2.434 NM_013358
PADI1
peptidyl arginine deiminase, type I
chr3_+_150125983 2.422 TSC22D2
TSC22 domain family, member 2
chr9_+_105757592 2.401 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr14_-_103995336 2.393


chr2_+_228678556 2.377 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr2_-_216300444 2.371 FN1
fibronectin 1
chr6_+_126661221 2.351 NM_001012507
CENPW
centromere protein W
chr19_+_45971249 2.329 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr11_-_119187811 2.302 NM_006500
MCAM
melanoma cell adhesion molecule
chr7_+_44646197 2.288 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr7_+_44646189 2.286 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr7_+_44646168 2.283 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr20_-_44420538 2.278 NM_080614
WFDC3
WAP four-disulfide core domain 3
chr4_-_122744782 2.241 CCNA2
cyclin A2
chr5_-_172198160 2.237 NM_004417
DUSP1
dual specificity phosphatase 1
chr10_+_106028630 2.181 NM_001191013
NM_183239
GSTO2

glutathione S-transferase omega 2

chr2_+_70142303 2.122 MXD1
MAX dimerization protein 1
chr3_+_44379923 2.117 NM_001029839
NM_173826
C3orf23

chromosome 3 open reading frame 23

chr4_-_122744978 2.080 NM_001237
CCNA2
cyclin A2
chr8_-_27695543 2.070 PBK
PDZ binding kinase
chr7_+_44646180 2.066 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr2_+_28615771 2.032 NM_005253
FOSL2
FOS-like antigen 2
chr12_+_13044352 2.021 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr11_-_2193015 2.020 NM_000360
NM_199292
NM_199293
TH


tyrosine hydroxylase


chr3_+_44380003 2.003 C3orf23
chromosome 3 open reading frame 23
chr10_-_106093662 1.998 NM_033397
ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
chr2_+_70142236 1.993 MXD1
MAX dimerization protein 1
chr17_+_65373362 1.987 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr3_+_8543508 1.968 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr1_-_204121144 1.958 NM_018208
ETNK2
ethanolamine kinase 2
chr19_+_54371150 1.938 MYADM
myeloid-associated differentiation marker
chr9_+_131644368 1.937 NM_001127245
NM_019594
LRRC8A

leucine rich repeat containing 8 family, member A

chr14_-_24732344 1.924 NM_000359
TGM1
transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)
chr6_-_53213747 1.910 NM_001242828
NM_001242830
NM_001242831
NM_021814
ELOVL5



ELOVL fatty acid elongase 5



chr16_-_4588738 1.907 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr3_+_38206968 1.896 NM_005109
OXSR1
oxidative-stress responsive 1
chr9_+_131644427 1.892 LRRC8A
leucine rich repeat containing 8 family, member A
chr1_-_204120909 1.876 ETNK2
ethanolamine kinase 2
chr17_-_8055684 1.876 NM_002616
PER1
period homolog 1 (Drosophila)
chr19_+_54371125 1.862 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr10_+_95256348 1.860 NM_001127182
NM_018131
CEP55

centrosomal protein 55kDa

chr17_+_65373574 1.856 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr1_-_110933635 1.847 SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr10_-_50342052 1.833 NM_001164484
FAM170B
family with sequence similarity 170, member B
chr9_-_140353785 1.814 NM_001130969
NM_001130970
NM_001130971
NM_001178064
NM_015537
NELF




nasal embryonic LHRH factor




chr11_+_13690246 1.809 FAR1
fatty acyl CoA reductase 1
chr17_+_33914320 1.783 AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr12_+_13044493 1.769 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr19_+_45349560 1.767 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr7_-_41742666 1.766 NM_002192
INHBA
inhibin, beta A
chr2_+_33172368 1.765 NM_206943
LTBP1
latent transforming growth factor beta binding protein 1
chr17_+_25621105 1.760 NM_015626
NM_134265
WSB1

WD repeat and SOCS box containing 1

chr14_+_93389444 1.750 NM_001275
CHGA
chromogranin A (parathyroid secretory protein 1)
chr15_-_63673918 1.737 CA12
carbonic anhydrase XII
chr6_-_88411872 1.727 AKIRIN2
akirin 2
chr17_-_43209681 1.725 NM_133373
PLCD3
phospholipase C, delta 3
chr6_-_88411948 1.724 AKIRIN2
akirin 2
chr15_-_63674074 1.723 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr17_+_33914357 1.706 AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr19_+_17666457 1.688 GLT25D1
glycosyltransferase 25 domain containing 1
chr9_-_140353748 1.676 NELF
nasal embryonic LHRH factor
chr11_-_64851556 1.647 NM_080668
CDCA5
cell division cycle associated 5
chr10_+_5566923 1.645 NM_005185
CALML3
calmodulin-like 3
chr2_-_220408264 1.643 NM_024536
CHPF
chondroitin polymerizing factor
chr2_+_30454396 1.630 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr3_+_8543539 1.626 LMCD1
LIM and cysteine-rich domains 1
chr14_-_94442894 1.625 ASB2
ankyrin repeat and SOCS box containing 2
chr1_+_152974222 1.614 NM_001097589
NM_005416
SPRR3

small proline-rich protein 3

chr22_+_38597938 1.582 NM_001161572
NM_001161574
NM_012323
MAFF


v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)


chr12_-_4754275 1.574 NM_006422
AKAP3
A kinase (PRKA) anchor protein 3
chr19_+_54371170 1.567 MYADM
myeloid-associated differentiation marker
chr7_+_134464417 1.548 CALD1
caldesmon 1
chr10_-_3827418 1.541 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr2_-_238322840 1.537 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr2_-_192015751 1.533 STAT4
signal transducer and activator of transcription 4
chr2_-_238322815 1.525 COL6A3
collagen, type VI, alpha 3
chr2_+_54785453 1.520 NM_178313
SPTBN1
spectrin, beta, non-erythrocytic 1
chr2_-_238322770 1.511 COL6A3
collagen, type VI, alpha 3
chr3_-_50374875 1.511 NM_170713
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr11_+_43963809 1.501 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr10_-_106098161 1.498 ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
chr11_+_117857062 1.486 NM_001558
IL10RA
interleukin 10 receptor, alpha
chr1_+_45205533 1.485 KIF2C
kinesin family member 2C
chr1_+_212209129 1.460 DTL
denticleless homolog (Drosophila)
chr1_+_209878135 1.447 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr6_-_127780534 1.446 NM_014702
KIAA0408
KIAA0408
chrX_-_132091223 1.420 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr7_-_45128492 1.417 NM_001146334
NACAD
NAC alpha domain containing
chr18_+_268147 1.410


chr8_-_27695288 1.408 NM_018492
PBK
PDZ binding kinase
chr4_+_1873035 1.405 NM_001042424
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chrX_+_43514157 1.405 MAOA
monoamine oxidase A
chr8_-_101964236 1.402 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr9_+_131644780 1.388 NM_001127244
LRRC8A
leucine rich repeat containing 8 family, member A
chr12_+_56915587 1.382 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr7_-_129592711 1.376 NM_001202498
UBE2H
ubiquitin-conjugating enzyme E2H
chr2_+_97001506 1.375 NCAPH
non-SMC condensin I complex, subunit H
chr1_-_110933683 1.373 NM_001201546
NM_001201547
NM_001201548
NM_001201549
NM_004696
SLC16A4




solute carrier family 16, member 4 (monocarboxylic acid transporter 5)




chr11_-_71159371 1.368 DHCR7
7-dehydrocholesterol reductase
chr20_+_58179601 1.362 NM_080672
PHACTR3
phosphatase and actin regulator 3
chr22_-_44258210 1.360 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr10_-_3827205 1.358 KLF6
Kruppel-like factor 6
chr1_+_212209112 1.355 DTL
denticleless homolog (Drosophila)
chr19_+_18723666 1.354 NM_012109
TMEM59L
transmembrane protein 59-like
chr7_-_129592794 1.340 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H

chr8_-_101964268 1.337 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr20_-_5591487 1.330 NM_019593
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr22_+_38598065 1.315 MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr16_+_31119730 1.311 BCKDK
branched chain ketoacid dehydrogenase kinase
chr8_-_101964258 1.307 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr3_+_100211554 1.303 TMEM45A
transmembrane protein 45A
chr3_-_124774735 1.296 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr9_-_131644176 1.294 NM_001122671
NM_001122672
NM_004059
CCBL1


cysteine conjugate-beta lyase, cytoplasmic


chr5_-_112770537 1.293 NM_032028
TSSK1B
testis-specific serine kinase 1B
chr7_-_73123431 1.287 STX1A
syntaxin 1A (brain)
chr8_-_144623611 1.276 NM_015117
ZC3H3
zinc finger CCCH-type containing 3
chr8_-_144623579 1.273 ZC3H3
zinc finger CCCH-type containing 3
chr5_-_72744351 1.266 NM_004472
FOXD1
forkhead box D1
chr19_-_49540072 1.265 NM_033377
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr19_+_17666502 1.262 NM_024656
GLT25D1
glycosyltransferase 25 domain containing 1
chr20_-_35201677 1.260


chr10_+_13203547 1.259 NM_018518
NM_182751
MCM10

minichromosome maintenance complex component 10

chr16_+_69139466 1.253 NM_001199280
HAS3
hyaluronan synthase 3
chr1_+_45205466 1.253 NM_006845
KIF2C
kinesin family member 2C
chr2_+_28615668 1.252 FOSL2
FOS-like antigen 2
chr12_+_71833518 1.248 LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr8_-_101964248 1.237 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr8_-_101964334 1.233 NM_145690
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr11_-_28129646 1.231 KIF18A
kinesin family member 18A
chr8_-_125740650 1.230 NM_014751
MTSS1
metastasis suppressor 1
chr8_-_101964247 1.229 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr7_-_158622184 1.226 ESYT2
extended synaptotagmin-like protein 2
chr11_-_64647136 1.226 EHD1
EH-domain containing 1
chr2_+_113735595 1.225 NM_019618
IL36G
interleukin 36, gamma
chr3_-_50374795 1.218 RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr22_+_44319674 1.217 PNPLA3
patatin-like phospholipase domain containing 3
chr11_+_66188474 1.217 NM_178864
NPAS4
neuronal PAS domain protein 4
chr7_+_38217919 1.215 STARD3NL
STARD3 N-terminal like
chr21_+_39628869 1.214 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr16_+_31119748 1.211 BCKDK
branched chain ketoacid dehydrogenase kinase
chr11_-_28129701 1.198 NM_031217
KIF18A
kinesin family member 18A
chr10_+_106028925 1.195 GSTO2
glutathione S-transferase omega 2
chr11_-_71159442 1.193 NM_001163817
NM_001360
DHCR7

7-dehydrocholesterol reductase

chr14_+_93389491 1.193 CHGA
chromogranin A (parathyroid secretory protein 1)
chr20_+_55099784 1.192 NM_001012971
FAM209A
FAM209B
family with sequence similarity 209, member A
family with sequence similarity 209, member B
chr9_+_112887780 1.192 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr11_-_28129687 1.190 KIF18A
kinesin family member 18A
chr11_-_119599253 1.190 NM_002855
NM_203285
NM_203286
PVRL1


poliovirus receptor-related 1 (herpesvirus entry mediator C)


chr15_-_70390226 1.183 TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr6_+_117586720 1.179 NM_153453
NM_182645
VGLL2

vestigial like 2 (Drosophila)

chr22_+_50528307 1.177 NM_001164104
NM_018995
MOV10L1

Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)

chr22_+_31487315 1.177 SMTN
smoothelin
chr13_+_32889594 1.174 NM_000059
BRCA2
breast cancer 2, early onset
chr15_+_93447702 1.160 CHD2
chromodomain helicase DNA binding protein 2
chr1_-_228604305 1.160 TRIM17
tripartite motif containing 17
chr3_-_48130633 1.158 NM_001134364
NM_002375
NM_030885
MAP4


microtubule-associated protein 4


chr12_+_13043955 1.156 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr11_-_125366048 1.142 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr9_+_125133322 1.142 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr17_-_8059637 1.138 PER1
period homolog 1 (Drosophila)
chr10_+_75936546 1.134 ADK
adenosine kinase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.10 5.82e-03 GO:0009987 cellular process
1.25 9.93e-03 GO:0023052 signaling
1.24 1.71e-02 GO:0032502 developmental process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 3.99e-04 GO:0005622 intracellular
1.14 4.04e-04 GO:0005737 cytoplasm
1.10 4.06e-04 GO:0044424 intracellular part
1.90 2.19e-02 GO:0015629 actin cytoskeleton
1.35 3.01e-02 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 6.80e-09 GO:0005515 protein binding
1.83 3.14e-04 GO:0008092 cytoskeletal protein binding
1.98 2.96e-03 GO:0003779 actin binding
1.08 1.03e-02 GO:0005488 binding