Motif ID: MAFB.p2

Z-value: 1.611


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAFBchr20_-_393178750.029.1e-01Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_76425207 2.283 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr3_-_45267068 2.172 TMEM158
transmembrane protein 158 (gene/pseudogene)
chrX_+_68725077 2.127 NM_015686
FAM155B
family with sequence similarity 155, member B
chr8_+_102504836 1.838 GRHL2
grainyhead-like 2 (Drosophila)
chr9_-_85677784 1.836 RASEF
RAS and EF-hand domain containing
chr2_+_191745546 1.797 NM_014905
GLS
glutaminase
chr17_+_7210841 1.583 NM_001970
EIF5A
eukaryotic translation initiation factor 5A
chr2_+_191745912 1.577 GLS
glutaminase
chr7_-_27183225 1.555 NM_019102
HOXA5
homeobox A5
chr4_+_75858205 1.516 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chrX_+_44732402 1.513 NM_021140
KDM6A
lysine (K)-specific demethylase 6A
chr16_+_82660573 1.468 CDH13
cadherin 13, H-cadherin (heart)
chr16_+_82660390 1.458 NM_001220488
NM_001220489
NM_001220490
NM_001220491
NM_001220492
NM_001257
CDH13





cadherin 13, H-cadherin (heart)





chr7_-_76256475 1.457 NM_012230
NM_152992
POMZP3

POM121 and ZP3 fusion

chr3_+_109128836 1.411 NM_001145553
FLJ25363
uncharacterized LOC401082
chr2_-_193059249 1.346 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr2_+_191745547 1.342 GLS
glutaminase
chr7_+_145813452 1.333 NM_014141
CNTNAP2
contactin associated protein-like 2
chr8_+_102504661 1.314 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr17_+_7210929 1.300 EIF5A
eukaryotic translation initiation factor 5A
chr11_-_61348290 1.299 NM_001252065
NM_004200
SYT7

synaptotagmin VII

chr2_+_191745568 1.294 GLS
glutaminase
chr8_+_7752198 1.281 NM_004942
DEFB4A
defensin, beta 4A
chr12_-_52779362 1.207 NM_033045
KRT84
keratin 84
chr9_-_33167084 1.171 B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr12_-_124068864 1.146


chr17_+_40610940 1.122 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr17_-_39768939 1.108 NM_005557
KRT16
keratin 16
chr17_+_40610897 1.103 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr17_+_7211260 1.101 NM_001143761
EIF5A
eukaryotic translation initiation factor 5A
chr17_+_40610875 1.094 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr12_+_69742140 1.084 LYZ
lysozyme
chr11_-_10830034 1.034 EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr15_-_90039776 1.011 NM_016321
RHCG
Rh family, C glycoprotein
chr4_-_57522469 0.982 NM_001145459
NM_139211
HOPX

HOP homeobox

chr12_+_69742130 0.970 NM_000239
LYZ
lysozyme
chr2_-_31361591 0.967 NM_001253826
NM_024572
GALNT14

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)

chr1_-_50489489 0.959 AGBL4
ATP/GTP binding protein-like 4
chr7_+_27135672 0.956 HOTAIRM1
HOXA transcript antisense RNA, myeloid-specific 1 (non-protein coding)
chr8_-_22550708 0.954 NM_004430
EGR3
early growth response 3
chr12_-_29936685 0.952 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr1_+_41445402 0.930 CTPS
CTP synthase
chr17_+_7942351 0.928 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr2_+_189156603 0.926 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr1_+_25943958 0.924 NM_020379
MAN1C1
mannosidase, alpha, class 1C, member 1
chr14_-_105444693 0.916 NM_138420
AHNAK2
AHNAK nucleoprotein 2
chr1_+_41445359 0.907 CTPS
CTP synthase
chr17_+_40610905 0.893 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr6_+_43139201 0.889 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr5_-_36151953 0.882 NM_001007527
LMBRD2
LMBR1 domain containing 2
chr9_-_110251754 0.870 KLF4
Kruppel-like factor 4 (gut)
chr12_+_32259655 0.868 BICD1
bicaudal D homolog 1 (Drosophila)
chr6_+_34204576 0.864 NM_002131
NM_145899
NM_145903
HMGA1


high mobility group AT-hook 1


chr10_-_79397394 0.862 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr8_-_121824015 0.859


chr12_-_111021122 0.843 PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr12_-_53242716 0.842 NM_173352
KRT78
keratin 78
chr19_+_50796820 0.826 MYH14
myosin, heavy chain 14, non-muscle
chr2_+_191745791 0.821 GLS
glutaminase
chr15_+_41851153 0.821 NM_006293
TYRO3
TYRO3 protein tyrosine kinase
chr19_+_16187047 0.776 NM_003290
TPM4
tropomyosin 4
chr19_+_16187266 0.771 TPM4
tropomyosin 4
chr20_+_1246959 0.762 NM_014723
SNPH
syntaphilin
chr19_+_1450208 0.756 APC2
adenomatosis polyposis coli 2
chr21_-_44846927 0.754 NM_173354
SIK1
salt-inducible kinase 1
chr10_-_79397204 0.752 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr19_+_16187306 0.742 TPM4
tropomyosin 4
chr19_+_16187315 0.740 TPM4
tropomyosin 4
chr2_-_10588273 0.739 ODC1
ornithine decarboxylase 1
chr7_+_44646197 0.736 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr7_+_44646168 0.729 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr17_+_40610857 0.725 NM_001130020
NM_001130021
NM_005177
ATP6V0A1


ATPase, H+ transporting, lysosomal V0 subunit a1


chr5_+_169780880 0.719 NM_001034838
KCNIP1
Kv channel interacting protein 1
chr2_-_10588451 0.718 NM_002539
ODC1
ornithine decarboxylase 1
chr15_-_27018108 0.710 GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr10_-_79397470 0.710 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr20_-_32700082 0.704 NM_003908
EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr7_+_76026819 0.699 NM_007155
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr11_-_111782447 0.692 NM_001885
CRYAB
crystallin, alpha B
chr20_-_33880203 0.692 NM_178468
FAM83C
family with sequence similarity 83, member C
chr9_+_139839697 0.689 NM_000606
C8G
complement component 8, gamma polypeptide
chr20_-_23030141 0.681 NM_000361
THBD
thrombomodulin
chr12_+_53491417 0.680 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr17_+_4402128 0.676 NM_001124758
SPNS2
spinster homolog 2 (Drosophila)
chr12_+_50794591 0.661 NM_001170803
NM_001170804
NM_001170808
NM_052879
NM_199188
NM_199190
LARP4





La ribonucleoprotein domain family, member 4





chr17_+_40610915 0.656 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr11_-_64646053 0.653 NM_006795
EHD1
EH-domain containing 1
chr12_-_76425375 0.651 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr12_-_111021026 0.643 NM_139283
PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr6_+_37787592 0.639 ZFAND3
zinc finger, AN1-type domain 3
chr9_-_33167230 0.638 B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr19_-_40791224 0.636 AKT2
v-akt murine thymoma viral oncogene homolog 2
chr3_-_160283166 0.636 KPNA4
karyopherin alpha 4 (importin alpha 3)
chr11_+_75479766 0.634 NM_032564
DGAT2
diacylglycerol O-acyltransferase 2
chr3_-_111314181 0.632 NM_024508
ZBED2
zinc finger, BED-type containing 2
chr1_+_26606580 0.632 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr6_-_108395939 0.631 NM_014028
OSTM1
osteopetrosis associated transmembrane protein 1
chr10_+_99400469 0.629 PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
chr5_-_44388666 0.628 NM_004465
FGF10
fibroblast growth factor 10
chr6_-_75994496 0.626 TMEM30A
transmembrane protein 30A
chr11_-_1330840 0.626 TOLLIP
toll interacting protein
chr17_+_900329 0.625 NM_013337
TIMM22
translocase of inner mitochondrial membrane 22 homolog (yeast)
chr16_+_29823408 0.619 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr19_+_45596159 0.615 PPP1R37
protein phosphatase 1, regulatory subunit 37
chr11_-_1330891 0.613 NM_019009
TOLLIP
toll interacting protein
chr2_-_55277459 0.613 RTN4
reticulon 4
chr11_-_64645925 0.612 EHD1
EH-domain containing 1
chr10_+_95326397 0.612 NM_001195755
NM_181745
O3FAR1

omega-3 fatty acid receptor 1

chr2_+_207308280 0.610 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr2_+_95537177 0.602 NM_144705
TEKT4
tektin 4
chr17_-_27278324 0.601 PHF12
PHD finger protein 12
chrX_+_47078053 0.600 NM_006201
CDK16
cyclin-dependent kinase 16
chr4_+_7045142 0.600 NM_152293
TADA2B
transcriptional adaptor 2B
chr17_+_40610899 0.598 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr9_-_77643307 0.593 NM_152420
C9orf41
chromosome 9 open reading frame 41
chr1_-_111991859 0.591 WDR77
WD repeat domain 77
chr6_+_34204663 0.589 HMGA1
high mobility group AT-hook 1
chr8_+_22224758 0.580 NM_001128431
NM_001135154
NM_015359
SLC39A14


solute carrier family 39 (zinc transporter), member 14


chr14_+_32546171 0.573 ARHGAP5
Rho GTPase activating protein 5
chr1_-_111991790 0.571 NM_024102
WDR77
WD repeat domain 77
chr12_-_63328663 0.567 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr3_-_131753757 0.566 NM_130808
CPNE4
copine IV
chr2_-_55277421 0.565 RTN4
reticulon 4
chr17_+_70117177 0.563 SOX9
SRY (sex determining region Y)-box 9
chr19_-_15560761 0.562 NM_021241
WIZ
widely interspaced zinc finger motifs
chr7_+_43622638 0.561 NM_004760
STK17A
serine/threonine kinase 17a
chr3_-_160283071 0.560 KPNA4
karyopherin alpha 4 (importin alpha 3)
chr5_+_95067511 0.560


chr8_+_22225173 0.560 SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr11_+_13690246 0.557 FAR1
fatty acyl CoA reductase 1
chr11_+_75479802 0.547 DGAT2
diacylglycerol O-acyltransferase 2
chr12_+_6875574 0.544 PTMS
parathymosin
chr17_-_40021616 0.543 NM_018143
KLHL11
kelch-like 11 (Drosophila)
chr14_+_32546208 0.542 ARHGAP5
Rho GTPase activating protein 5
chr16_-_12009804 0.539 NM_001130006
NM_002094
GSPT1

G1 to S phase transition 1

chr4_-_57547845 0.539 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr5_-_132298973 0.538 AFF4
AF4/FMR2 family, member 4
chr8_-_22550057 0.537 NM_001199881
EGR3
early growth response 3
chr6_+_45390376 0.532 RUNX2
runt-related transcription factor 2
chr3_+_50649292 0.531 NM_001243926
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr10_-_79397290 0.531 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr7_-_76256144 0.530 POMZP3
POM121 and ZP3 fusion
chr13_-_26625164 0.528 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr16_-_66730466 0.523 NM_178818
NM_181521
CMTM4

CKLF-like MARVEL transmembrane domain containing 4

chr6_+_34204647 0.522 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr3_-_119812512 0.522 GSK3B
glycogen synthase kinase 3 beta
chr2_+_10091791 0.518 NM_198182
GRHL1
grainyhead-like 1 (Drosophila)
chr7_-_23509972 0.517 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr9_-_77643156 0.517 C9orf41
chromosome 9 open reading frame 41
chr2_+_99953749 0.515 NM_015904
EIF5B
eukaryotic translation initiation factor 5B
chr1_-_245027610 0.514 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr2_+_176957448 0.513 NM_000523
HOXD13
homeobox D13
chrX_+_24167728 0.511 NM_001178086
NM_001178095
NM_001178084
NM_001178085
NM_003410
ZFX




zinc finger protein, X-linked




chr6_+_45390284 0.511 RUNX2
runt-related transcription factor 2
chr2_-_100721128 0.510 AFF3
AF4/FMR2 family, member 3
chr3_+_152552735 0.509 NM_002563
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr10_-_115934363 0.508 NM_018017
C10orf118
chromosome 10 open reading frame 118
chr2_+_189156730 0.506 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr2_+_64681270 0.505 NM_014181
LGALSL
lectin, galactoside-binding-like
chr1_+_24645914 0.505 NM_001195010
GRHL3
grainyhead-like 3 (Drosophila)
chr19_+_13229101 0.504 NM_052876
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr1_+_26606586 0.503 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr19_+_1450117 0.502 NM_005883
APC2
adenomatosis polyposis coli 2
chr3_-_45267620 0.502 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr14_+_69865095 0.501 NM_001252151
NM_001252152
SLC39A9

solute carrier family 39 (zinc transporter), member 9

chr2_-_237076613 0.500 NM_001485
GBX2
gastrulation brain homeobox 2
chr8_-_101964236 0.499 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr1_-_155532152 0.498 ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chrX_-_6145887 0.494 NM_020742
NLGN4X
neuroligin 4, X-linked
chr6_+_147524866 0.494 STXBP5
syntaxin binding protein 5 (tomosyn)
chr5_-_139726173 0.492 NM_001945
HBEGF
heparin-binding EGF-like growth factor
chr3_-_122233764 0.489 KPNA1
karyopherin alpha 1 (importin alpha 5)
chr16_-_1843652 0.489 NM_001146006
NM_004970
IGFALS

insulin-like growth factor binding protein, acid labile subunit

chr10_+_72163914 0.484 EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr9_-_110252045 0.483 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr1_+_183441649 0.482 SMG7
smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr19_+_50706868 0.480 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr3_-_45267804 0.478 NM_015444
TMEM158
transmembrane protein 158 (gene/pseudogene)
chr3_+_133292714 0.475 CDV3
CDV3 homolog (mouse)
chr7_+_30634401 0.475 GARS
glycyl-tRNA synthetase
chr16_-_12009568 0.474


chr12_-_52828105 0.471 NM_004693
KRT75
keratin 75
chr12_-_52845862 0.471 NM_005555
KRT6B
keratin 6B
chr19_-_3557551 0.468 MFSD12
major facilitator superfamily domain containing 12
chr6_-_112194430 0.468 FYN
FYN oncogene related to SRC, FGR, YES
chr5_+_129240453 0.468 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr9_-_86322593 0.465 UBQLN1
ubiquilin 1
chr19_+_10216898 0.462 NM_020230
NM_001040664
NM_001198690
PPAN
PPAN-P2RY11

peter pan homolog (Drosophila)
PPAN-P2RY11 readthrough

chr14_+_69865380 0.459 NM_001252148
NM_001252150
NM_018375
SLC39A9


solute carrier family 39 (zinc transporter), member 9


chr11_-_71159371 0.457 DHCR7
7-dehydrocholesterol reductase
chr16_+_610393 0.455 NM_145270
C16orf11
chromosome 16 open reading frame 11
chr8_+_27183047 0.454 PTK2B
PTK2B protein tyrosine kinase 2 beta
chr20_-_35374530 0.454 NM_022477
NM_032013
NDRG3

NDRG family member 3

chr2_+_101436491 0.453 NM_002518
NPAS2
neuronal PAS domain protein 2
chr1_+_110082493 0.452 NM_031936
GPR61
G protein-coupled receptor 61
chr15_-_59041933 0.451 NM_001110
ADAM10
ADAM metallopeptidase domain 10
chr1_-_108742806 0.451 SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr9_-_77643179 0.450 C9orf41
chromosome 9 open reading frame 41
chr1_+_202317798 0.448 NM_001167857
NM_001167858
NM_002481
PPP1R12B


protein phosphatase 1, regulatory subunit 12B


chr19_-_40791145 0.447 AKT2
v-akt murine thymoma viral oncogene homolog 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.12 3.80e-22 GO:0009987 cellular process
1.17 4.64e-16 GO:0050794 regulation of cellular process
1.15 2.02e-14 GO:0065007 biological regulation
1.44 3.61e-14 GO:0007399 nervous system development
1.15 1.45e-13 GO:0050789 regulation of biological process
1.28 4.97e-12 GO:0048731 system development
1.23 1.12e-11 GO:0023052 signaling
1.26 1.58e-11 GO:0048856 anatomical structure development
1.30 1.84e-11 GO:0048522 positive regulation of cellular process
1.51 3.97e-11 GO:0048468 cell development
1.27 3.07e-10 GO:0048518 positive regulation of biological process
1.21 9.75e-10 GO:0032502 developmental process
1.23 1.08e-09 GO:0007275 multicellular organismal development
1.48 1.41e-09 GO:0022008 neurogenesis
1.15 1.61e-09 GO:0044237 cellular metabolic process
1.57 2.03e-09 GO:0007167 enzyme linked receptor protein signaling pathway
1.30 3.35e-09 GO:0030154 cell differentiation
1.64 3.73e-09 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.41 4.82e-09 GO:0010604 positive regulation of macromolecule metabolic process
1.39 5.22e-09 GO:0009893 positive regulation of metabolic process
1.48 7.38e-09 GO:0048699 generation of neurons
1.29 9.17e-09 GO:0048523 negative regulation of cellular process
1.29 1.18e-08 GO:0048869 cellular developmental process
1.57 3.56e-08 GO:0048666 neuron development
1.18 4.66e-08 GO:0044260 cellular macromolecule metabolic process
1.20 4.79e-08 GO:0031323 regulation of cellular metabolic process
1.26 5.11e-08 GO:0048519 negative regulation of biological process
1.61 5.89e-08 GO:0000904 cell morphogenesis involved in differentiation
1.38 5.99e-08 GO:0031325 positive regulation of cellular metabolic process
1.51 7.60e-08 GO:0030182 neuron differentiation
1.32 1.07e-07 GO:0023051 regulation of signaling
1.21 1.19e-07 GO:0007165 signal transduction
1.48 1.71e-07 GO:0010557 positive regulation of macromolecule biosynthetic process
1.24 5.26e-07 GO:0044267 cellular protein metabolic process
1.32 5.79e-07 GO:0009653 anatomical structure morphogenesis
1.40 5.84e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.18 6.14e-07 GO:0019222 regulation of metabolic process
1.49 6.57e-07 GO:0010628 positive regulation of gene expression
1.13 7.47e-07 GO:0044238 primary metabolic process
1.56 1.10e-06 GO:0007417 central nervous system development
1.57 1.29e-06 GO:0031175 neuron projection development
1.45 1.51e-06 GO:0007267 cell-cell signaling
1.39 1.64e-06 GO:0006793 phosphorus metabolic process
1.39 1.64e-06 GO:0006796 phosphate metabolic process
1.34 2.20e-06 GO:0051641 cellular localization
1.11 2.46e-06 GO:0008152 metabolic process
1.37 2.75e-06 GO:0010646 regulation of cell communication
1.36 3.16e-06 GO:0051649 establishment of localization in cell
1.27 3.17e-06 GO:0006464 protein modification process
1.59 4.16e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.19 4.19e-06 GO:0080090 regulation of primary metabolic process
1.26 4.22e-06 GO:0043412 macromolecule modification
1.19 4.33e-06 GO:0016043 cellular component organization
1.41 4.90e-06 GO:0031328 positive regulation of cellular biosynthetic process
1.18 5.28e-06 GO:0051179 localization
1.48 5.92e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.41 6.44e-06 GO:0009891 positive regulation of biosynthetic process
1.46 7.67e-06 GO:0051254 positive regulation of RNA metabolic process
1.49 8.08e-06 GO:0000902 cell morphogenesis
1.57 8.31e-06 GO:0048812 neuron projection morphogenesis
1.37 1.07e-05 GO:0007154 cell communication
1.18 1.11e-05 GO:0071840 cellular component organization or biogenesis
1.40 1.33e-05 GO:0016310 phosphorylation
1.19 1.35e-05 GO:0060255 regulation of macromolecule metabolic process
1.42 1.40e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.14 1.47e-05 GO:0043170 macromolecule metabolic process
1.58 1.51e-05 GO:0007409 axonogenesis
1.42 2.64e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 2.75e-05 GO:0007166 cell surface receptor linked signaling pathway
1.45 3.02e-05 GO:0030030 cell projection organization
1.16 3.68e-05 GO:0051716 cellular response to stimulus
1.25 4.41e-05 GO:0048513 organ development
1.30 8.58e-05 GO:0051239 regulation of multicellular organismal process
1.28 1.08e-04 GO:0009966 regulation of signal transduction
1.22 1.10e-04 GO:0042221 response to chemical stimulus
1.19 1.15e-04 GO:0006810 transport
1.49 1.19e-04 GO:0048858 cell projection morphogenesis
1.49 1.28e-04 GO:0032990 cell part morphogenesis
1.29 1.32e-04 GO:0035556 intracellular signal transduction
1.44 1.34e-04 GO:0032989 cellular component morphogenesis
1.38 1.55e-04 GO:0046907 intracellular transport
1.59 2.64e-04 GO:0007411 axon guidance
1.20 2.76e-04 GO:0010468 regulation of gene expression
1.59 3.22e-04 GO:0009259 ribonucleotide metabolic process
1.18 3.23e-04 GO:0051234 establishment of localization
1.80 4.33e-04 GO:0032869 cellular response to insulin stimulus
1.19 5.20e-04 GO:0031326 regulation of cellular biosynthetic process
1.59 5.48e-04 GO:0009150 purine ribonucleotide metabolic process
1.18 5.57e-04 GO:0019538 protein metabolic process
1.19 6.24e-04 GO:0009889 regulation of biosynthetic process
1.48 6.57e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.20 7.07e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.70 7.45e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.60 8.01e-04 GO:0009199 ribonucleoside triphosphate metabolic process
1.20 8.34e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.32 9.16e-04 GO:0032268 regulation of cellular protein metabolic process
1.69 9.43e-04 GO:0071375 cellular response to peptide hormone stimulus
1.37 9.45e-04 GO:0006468 protein phosphorylation
1.59 1.20e-03 GO:0009144 purine nucleoside triphosphate metabolic process
1.58 1.23e-03 GO:0009141 nucleoside triphosphate metabolic process
1.59 1.30e-03 GO:0009205 purine ribonucleoside triphosphate metabolic process
1.34 1.55e-03 GO:0040011 locomotion
1.44 1.57e-03 GO:0034613 cellular protein localization
1.31 2.05e-03 GO:0032879 regulation of localization
1.43 2.43e-03 GO:0070727 cellular macromolecule localization
1.19 2.68e-03 GO:0044249 cellular biosynthetic process
1.49 2.91e-03 GO:0006886 intracellular protein transport
1.29 3.09e-03 GO:0051246 regulation of protein metabolic process
1.33 3.14e-03 GO:0006351 transcription, DNA-dependent
1.49 3.18e-03 GO:0006163 purine nucleotide metabolic process
1.78 3.38e-03 GO:0006813 potassium ion transport
1.47 3.63e-03 GO:0007268 synaptic transmission
1.36 4.16e-03 GO:0019220 regulation of phosphate metabolic process
1.36 4.16e-03 GO:0051174 regulation of phosphorus metabolic process
1.55 4.22e-03 GO:0032870 cellular response to hormone stimulus
1.18 4.24e-03 GO:0009058 biosynthetic process
1.65 4.27e-03 GO:0009261 ribonucleotide catabolic process
1.15 4.34e-03 GO:0006807 nitrogen compound metabolic process
1.18 4.72e-03 GO:0071842 cellular component organization at cellular level
1.16 4.73e-03 GO:0034641 cellular nitrogen compound metabolic process
1.83 4.76e-03 GO:0008286 insulin receptor signaling pathway
1.22 5.33e-03 GO:0016070 RNA metabolic process
1.46 5.40e-03 GO:0032583 regulation of gene-specific transcription
1.70 5.64e-03 GO:0034220 ion transmembrane transport
1.64 5.74e-03 GO:0009154 purine ribonucleotide catabolic process
1.61 5.91e-03 GO:0006195 purine nucleotide catabolic process
1.21 6.43e-03 GO:0010467 gene expression
1.17 6.46e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46 6.47e-03 GO:0072521 purine-containing compound metabolic process
1.19 6.70e-03 GO:0065008 regulation of biological quality
1.57 6.95e-03 GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
1.57 6.95e-03 GO:0034656 nucleobase, nucleoside and nucleotide catabolic process
1.39 7.27e-03 GO:0042060 wound healing
1.45 7.76e-03 GO:0010648 negative regulation of cell communication
1.52 7.95e-03 GO:0071495 cellular response to endogenous stimulus
1.62 8.15e-03 GO:0032868 response to insulin stimulus
1.34 8.61e-03 GO:0016192 vesicle-mediated transport
1.51 8.64e-03 GO:0043434 response to peptide hormone stimulus
1.41 9.28e-03 GO:0006935 chemotaxis
1.41 9.28e-03 GO:0042330 taxis
1.49 9.87e-03 GO:0007420 brain development
1.11 9.87e-03 GO:0032501 multicellular organismal process
1.59 1.00e-02 GO:0072523 purine-containing compound catabolic process
1.71 1.01e-02 GO:0043687 post-translational protein modification
1.17 1.03e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.63 1.03e-02 GO:0009203 ribonucleoside triphosphate catabolic process
1.63 1.03e-02 GO:0009207 purine ribonucleoside triphosphate catabolic process
1.46 1.11e-02 GO:0009968 negative regulation of signal transduction
1.44 1.14e-02 GO:0023057 negative regulation of signaling
1.57 1.16e-02 GO:0009166 nucleotide catabolic process
1.62 1.18e-02 GO:0009143 nucleoside triphosphate catabolic process
1.35 1.23e-02 GO:0009790 embryo development
1.62 1.28e-02 GO:0009146 purine nucleoside triphosphate catabolic process
1.41 1.39e-02 GO:0019226 transmission of nerve impulse
1.41 1.39e-02 GO:0035637 multicellular organismal signaling
1.16 1.42e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.66 1.53e-02 GO:0048732 gland development
1.21 1.70e-02 GO:0009059 macromolecule biosynthetic process
1.35 1.74e-02 GO:0045595 regulation of cell differentiation
1.16 1.85e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.50 1.87e-02 GO:0032535 regulation of cellular component size
1.34 2.07e-02 GO:0009719 response to endogenous stimulus
1.28 2.09e-02 GO:0042127 regulation of cell proliferation
1.20 2.28e-02 GO:0048583 regulation of response to stimulus
1.29 2.33e-02 GO:0050793 regulation of developmental process
1.27 2.36e-02 GO:0042981 regulation of apoptosis
1.27 2.41e-02 GO:0043067 regulation of programmed cell death
1.44 2.47e-02 GO:0007243 intracellular protein kinase cascade
1.44 2.47e-02 GO:0023014 signal transduction via phosphorylation event
1.37 2.57e-02 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.44 2.71e-02 GO:0016477 cell migration
1.32 2.89e-02 GO:2000026 regulation of multicellular organismal development
1.49 3.15e-02 GO:0001501 skeletal system development
1.26 3.25e-02 GO:0010941 regulation of cell death
1.21 3.45e-02 GO:0034645 cellular macromolecule biosynthetic process
1.42 3.66e-02 GO:0060341 regulation of cellular localization
1.28 3.70e-02 GO:0032774 RNA biosynthetic process
1.29 3.88e-02 GO:0008219 cell death
1.29 3.94e-02 GO:0016265 death
1.44 4.39e-02 GO:0007264 small GTPase mediated signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 1.95e-15 GO:0005622 intracellular
1.09 1.03e-14 GO:0044424 intracellular part
1.13 1.56e-13 GO:0005737 cytoplasm
1.16 1.04e-11 GO:0044444 cytoplasmic part
1.09 7.74e-08 GO:0043229 intracellular organelle
1.09 9.04e-08 GO:0043226 organelle
1.20 7.91e-07 GO:0043234 protein complex
1.24 2.43e-06 GO:0005829 cytosol
1.13 5.42e-06 GO:0044446 intracellular organelle part
1.12 1.03e-05 GO:0044422 organelle part
1.09 1.16e-05 GO:0043231 intracellular membrane-bounded organelle
1.08 1.18e-05 GO:0043227 membrane-bounded organelle
1.16 7.86e-05 GO:0032991 macromolecular complex
1.44 7.34e-04 GO:0005768 endosome
1.23 7.92e-04 GO:0012505 endomembrane system
1.33 7.95e-04 GO:0031410 cytoplasmic vesicle
1.32 9.17e-04 GO:0031982 vesicle
1.34 1.02e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.33 1.24e-03 GO:0031988 membrane-bounded vesicle
1.19 1.98e-03 GO:0031090 organelle membrane
1.45 2.11e-03 GO:0043005 neuron projection
1.03 2.16e-03 GO:0044464 cell part
1.03 2.29e-03 GO:0005623 cell
1.44 2.59e-03 GO:0045202 synapse
1.26 3.15e-03 GO:0000267 cell fraction
1.26 6.69e-03 GO:0005794 Golgi apparatus
1.29 6.91e-03 GO:0005626 insoluble fraction
1.61 1.28e-02 GO:0031252 cell leading edge
1.42 2.43e-02 GO:0048471 perinuclear region of cytoplasm
1.27 2.44e-02 GO:0005624 membrane fraction
1.47 2.74e-02 GO:0012506 vesicle membrane
1.43 3.10e-02 GO:0044433 cytoplasmic vesicle part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 4.01e-27 GO:0005515 protein binding
1.08 5.58e-13 GO:0005488 binding
1.25 5.98e-08 GO:0000166 nucleotide binding
1.27 5.02e-07 GO:0032553 ribonucleotide binding
1.27 5.02e-07 GO:0032555 purine ribonucleotide binding
1.26 8.72e-07 GO:0017076 purine nucleotide binding
1.28 3.74e-06 GO:0032559 adenyl ribonucleotide binding
1.27 7.96e-06 GO:0030554 adenyl nucleotide binding
1.25 9.89e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.38 6.38e-05 GO:0019899 enzyme binding
1.26 7.38e-05 GO:0005524 ATP binding
1.32 1.40e-04 GO:0001071 nucleic acid binding transcription factor activity
1.32 1.40e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.37 5.12e-04 GO:0043565 sequence-specific DNA binding
1.41 9.67e-04 GO:0008092 cytoskeletal protein binding
1.28 2.99e-03 GO:0030528 transcription regulator activity
1.31 7.15e-03 GO:0016301 kinase activity
1.34 8.77e-03 GO:0004672 protein kinase activity
1.31 1.35e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.38 2.43e-02 GO:0030695 GTPase regulator activity
1.73 2.50e-02 GO:0005267 potassium channel activity
1.87 2.54e-02 GO:0017016 Ras GTPase binding
1.47 2.94e-02 GO:0005083 small GTPase regulator activity
1.97 4.11e-02 GO:0005200 structural constituent of cytoskeleton