Motif ID: MTF1.p2

Z-value: 1.266


Transcription factors associated with MTF1.p2:

Gene SymbolEntrez IDGene Name
MTF1 4520 metal-regulatory transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MTF1chr1_-_383252240.163.9e-01Click!


Activity profile for motif MTF1.p2.

activity profile for motif MTF1.p2


Sorted Z-values histogram for motif MTF1.p2

Sorted Z-values for motif MTF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MTF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_121824268 3.058 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr19_+_708766 2.686 NM_001040134
NM_002579
PALM

paralemmin

chr8_-_121824015 2.308


chr2_+_121103670 2.187 NM_002193
INHBB
inhibin, beta B
chr8_-_121824287 2.123 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr14_-_100625931 2.094 NM_206918
DEGS2
delta(4)-desaturase, sphingolipid 2
chr20_-_55841090 1.936 BMP7
bone morphogenetic protein 7
chr7_+_4722091 1.866 FOXK1
forkhead box K1
chr19_-_18717467 1.844 CRLF1
cytokine receptor-like factor 1
chr22_+_39853316 1.841 NM_002409
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr19_-_18717631 1.816 NM_004750
CRLF1
cytokine receptor-like factor 1
chr20_-_39317875 1.742 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr15_-_93616308 1.640 RGMA
RGM domain family, member A
chr16_-_52580805 1.633 NM_001080430
TOX3
TOX high mobility group box family member 3
chr22_-_31741761 1.618 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr16_+_67465019 1.595 NM_000196
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr8_-_140715234 1.588 NM_016601
KCNK9
potassium channel, subfamily K, member 9
chr3_+_13590624 1.579 NM_001004019
NM_001998
FBLN2

fibulin 2

chr3_+_13590644 1.567 FBLN2
fibulin 2
chr3_-_45267804 1.527 NM_015444
TMEM158
transmembrane protein 158 (gene/pseudogene)
chr4_+_187065994 1.502 NM_015398
FAM149A
family with sequence similarity 149, member A
chr9_-_33167166 1.447 B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr19_-_14316980 1.440 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr13_-_26625164 1.420 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr15_-_93616358 1.408 NM_001166286
RGMA
RGM domain family, member A
chr9_-_33167084 1.397 B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr22_-_50970542 1.370 ODF3B
outer dense fiber of sperm tails 3B
chr15_+_101459459 1.343 NM_024652
LRRK1
leucine-rich repeat kinase 1
chr14_+_105953531 1.338 CRIP1
cysteine-rich protein 1 (intestinal)
chr7_-_51384458 1.313 NM_015198
COBL
cordon-bleu homolog (mouse)
chr13_-_36705432 1.289 DCLK1
doublecortin-like kinase 1
chrX_+_152240726 1.281 NM_001170944
NM_001242319
NM_032882
PNMA6C
PNMA6D
PNMA6A
paraneoplastic antigen like 6C
paraneoplastic antigen like 6D
paraneoplastic antigen like 6A
chr22_+_29279573 1.274 NM_001206998
ZNRF3
zinc and ring finger 3
chr9_-_139922705 1.271 NM_001606
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr22_+_39853534 1.264 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr11_-_2292181 1.249 NM_005170
ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr5_-_111093792 1.215 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr11_+_61276271 1.191 NM_001145077
LRRC10B
leucine rich repeat containing 10B
chr16_-_56459371 1.137 NM_001144
AMFR
autocrine motility factor receptor
chr9_-_33167230 1.125 B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr11_+_111169965 1.096 NM_001136105
C11orf93
chromosome 11 open reading frame 93
chr22_-_31742217 1.084 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr21_+_44073650 1.075 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr5_+_76506705 1.068 NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719
PDE8B




phosphodiesterase 8B




chr10_-_28287790 1.063 NM_018076
ARMC4
armadillo repeat containing 4
chrX_+_68725077 1.062 NM_015686
FAM155B
family with sequence similarity 155, member B
chr15_-_101459410 1.044


chr9_-_139922595 1.015 ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr22_+_43808011 1.014 NM_001044370
MPPED1
metallophosphoesterase domain containing 1
chrX_-_8700170 0.992 NM_000216
KAL1
Kallmann syndrome 1 sequence
chr9_-_33167355 0.992 NM_001497
B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr5_+_156693051 0.987 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr7_-_51384331 0.982 COBL
cordon-bleu homolog (mouse)
chr20_-_3154169 0.978 ProSAPiP1
ProSAPiP1 protein
chr19_-_18717577 0.977 CRLF1
cytokine receptor-like factor 1
chr20_-_55841671 0.975 NM_001719
BMP7
bone morphogenetic protein 7
chr14_+_105953256 0.970 NM_001311
CRIP1
cysteine-rich protein 1 (intestinal)
chr10_-_13043570 0.968 NM_031455
CCDC3
coiled-coil domain containing 3
chr7_-_82073020 0.948 NM_000722
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr3_-_50540853 0.942 NM_001005505
NM_001174051
NM_006030
CACNA2D2


calcium channel, voltage-dependent, alpha 2/delta subunit 2


chr8_+_144099900 0.929 NM_001127213
NM_002346
LY6E

lymphocyte antigen 6 complex, locus E

chr1_-_22469414 0.908 NM_030761
WNT4
wingless-type MMTV integration site family, member 4
chr6_+_35227478 0.896 NM_003427
ZNF76
zinc finger protein 76
chr2_+_113993082 0.887 LOC654433
uncharacterized LOC654433
chr3_-_45267620 0.883 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr12_+_50355278 0.882 NM_001651
AQP5
aquaporin 5
chr15_-_93616891 0.874 NM_001166288
NM_001166289
RGMA

RGM domain family, member A

chr19_+_18111923 0.871 NM_001025604
ARRDC2
arrestin domain containing 2
chr1_+_151694012 0.861 NM_001144956
RIIAD1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chr1_-_109656478 0.858 NM_001122961
C1orf194
chromosome 1 open reading frame 194
chr19_-_17137449 0.858 NM_015692
CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr8_+_56015013 0.843 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr11_+_121322848 0.843 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr4_-_16085666 0.835 PROM1
prominin 1
chr2_+_85980600 0.829 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr10_-_61469322 0.820 NM_194298
LOC100129721
SLC16A9
uncharacterized LOC100129721
solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr2_-_230579198 0.820 NM_139072
DNER
delta/notch-like EGF repeat containing
chr19_-_5340700 0.819 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr8_+_136469557 0.811 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr14_+_102027687 0.809 NM_001362
DIO3
deiodinase, iodothyronine, type III
chr3_+_186648515 0.806 ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr19_+_49617631 0.800 LIN7B
lin-7 homolog B (C. elegans)
chr2_+_217498082 0.799 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr1_+_228870801 0.798 NM_021205
RHOU
ras homolog gene family, member U
chr9_-_95896498 0.796 NM_004148
NINJ1
ninjurin 1
chr7_-_131241321 0.795 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr5_-_111093251 0.789 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr5_+_10442065 0.774 ROPN1L
rhophilin associated tail protein 1-like
chr21_+_42676176 0.769 FAM3B
family with sequence similarity 3, member B
chr4_+_106068009 0.764 TET2
tet methylcytosine dioxygenase 2
chr5_+_10441973 0.763 NM_001201466
NM_031916
ROPN1L

rhophilin associated tail protein 1-like

chr1_-_23751126 0.749 NM_003196
TCEA3
transcription elongation factor A (SII), 3
chr1_+_33722158 0.736 NM_152493
ZNF362
zinc finger protein 362
chr6_-_43477980 0.730 LRRC73
leucine rich repeat containing 73
chr11_+_6411637 0.725 NM_000543
NM_001007593
SMPD1

sphingomyelin phosphodiesterase 1, acid lysosomal

chr18_-_45935627 0.724 ZBTB7C
zinc finger and BTB domain containing 7C
chr19_+_49617611 0.722 NM_022165
LIN7B
lin-7 homolog B (C. elegans)
chr1_-_1535446 0.722 NM_001242659
LOC643988
uncharacterized LOC643988
chr4_+_95679075 0.719 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr5_+_133450353 0.710 NM_003202
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr16_-_755718 0.709 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr6_+_24495166 0.704 NM_001080
NM_170740
ALDH5A1

aldehyde dehydrogenase 5 family, member A1

chr7_+_142552547 0.692 NM_004445
EPHB6
EPH receptor B6
chr10_+_12391708 0.692 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr1_-_241520384 0.691 RGS7
regulator of G-protein signaling 7
chr20_+_36531548 0.689 VSTM2L
V-set and transmembrane domain containing 2 like
chr9_+_140317803 0.689 NM_006647
NOXA1
NADPH oxidase activator 1
chr1_-_159869897 0.684 NM_012337
CCDC19
coiled-coil domain containing 19
chr12_+_102091399 0.670 NM_020244
CHPT1
choline phosphotransferase 1
chr19_+_1000295 0.665 NM_138690
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr19_+_33685140 0.663 LRP3
low density lipoprotein receptor-related protein 3
chr8_-_110704019 0.661 NM_001099743
NM_001099744
SYBU

syntabulin (syntaxin-interacting)

chr6_+_35227234 0.657 ZNF76
zinc finger protein 76
chr19_-_47922391 0.655 MEIS3
Meis homeobox 3
chr11_+_45907046 0.650 NM_005456
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr11_-_2016743 0.649 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr20_-_3218834 0.644 NM_001174090
SLC4A11
solute carrier family 4, sodium borate transporter, member 11
chr1_+_3569098 0.642 NM_001204184
NM_001204185
NM_001204186
NM_001204187
NM_001204188
NM_005427
TP73





tumor protein p73





chr17_+_8924822 0.640 NM_004822
NTN1
netrin 1
chr19_-_70944 0.640 WASH5P
WAS protein family homolog 5 pseudogene
chr3_-_50383009 0.638 NM_015896
ZMYND10
zinc finger, MYND-type containing 10
chr15_+_84322809 0.638 NM_207517
ADAMTSL3
ADAMTS-like 3
chr20_-_47444404 0.637 NM_020820
PREX1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr10_+_70587562 0.635 NM_001130162
STOX1
storkhead box 1
chr20_-_4804067 0.633 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr16_-_66959418 0.630 NM_001128850
NM_004165
RRAD

Ras-related associated with diabetes

chr22_-_42310670 0.627 NM_001207020
SHISA8
shisa homolog 8 (Xenopus laevis)
chr22_-_31742329 0.627 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr19_-_7990974 0.623 NM_206833
CTXN1
cortexin 1
chr1_+_4715104 0.619 NM_001042478
NM_018836
AJAP1

adherens junctions associated protein 1

chr11_-_75062650 0.617 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr9_-_130639939 0.612 NM_000476
AK1
adenylate kinase 1
chr2_+_217498205 0.610 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr10_+_12391728 0.610 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr12_+_50451486 0.604 NM_001095
NM_020039
ACCN2

amiloride-sensitive cation channel 2, neuronal

chr17_+_72667255 0.603 NM_175738
RAB37
RAB37, member RAS oncogene family
chr16_+_2083264 0.594 NM_001252073
NM_001252075
NM_001252076
SLC9A3R2


solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2


chr20_+_44098392 0.593 NM_006103
WFDC2
WAP four-disulfide core domain 2
chr5_+_56110899 0.588 NM_005921
MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr16_+_58549382 0.587 NM_001160305
NM_024860
SETD6

SET domain containing 6

chr9_-_80646150 0.580 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr2_-_239197091 0.574 NM_022817
PER2
period homolog 2 (Drosophila)
chr17_-_3796270 0.573 CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr17_+_40440481 0.573 STAT5A
signal transducer and activator of transcription 5A
chr4_-_46995440 0.571 NM_001204266
NM_001204267
GABRA4

gamma-aminobutyric acid (GABA) A receptor, alpha 4

chr17_-_3796336 0.571 NM_032294
NM_172207
CAMKK1

calcium/calmodulin-dependent protein kinase kinase 1, alpha

chr17_-_63557764 0.570 AXIN2
axin 2
chr13_+_37005966 0.570 NM_001111046
NM_001111047
CCNA1

cyclin A1

chr7_+_139208673 0.570 NM_001080511
CLEC2L
C-type lectin domain family 2, member L
chrX_+_49126326 0.555 PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr8_+_1711869 0.555 NM_018941
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr2_+_191273012 0.553 NM_017694
MFSD6
major facilitator superfamily domain containing 6
chr14_+_105331581 0.552 NM_001112726
NM_015005
KIAA0284

KIAA0284

chr9_+_34958171 0.552 NM_015297
KIAA1045
KIAA1045
chr9_-_33167300 0.552 B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chrX_-_108868250 0.552 NM_012282
KCNE1L
KCNE1-like
chr3_-_45267068 0.551 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr20_-_40246991 0.551 NM_032221
CHD6
chromodomain helicase DNA binding protein 6
chr9_-_112260529 0.549 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr17_-_63557615 0.547 NM_004655
AXIN2
axin 2
chr1_-_241520467 0.544 NM_002924
RGS7
regulator of G-protein signaling 7
chr1_+_228871109 0.543 RHOU
ras homolog gene family, member U
chr1_+_205538111 0.540 NM_181644
MFSD4
major facilitator superfamily domain containing 4
chr22_-_31741565 0.536 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr9_+_17578952 0.535 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr14_-_93673360 0.533 NM_032490
C14orf142
chromosome 14 open reading frame 142
chr7_+_3340919 0.533 NM_152744
SDK1
sidekick cell adhesion molecule 1
chr2_-_39187477 0.528 LOC375196
uncharacterized LOC375196
chr3_+_13610239 0.527 NM_001165035
FBLN2
fibulin 2
chr1_+_218519576 0.520 TGFB2
transforming growth factor, beta 2
chr20_-_25038501 0.518 NM_001252675
NM_001252677
NM_032501
ACSS1


acyl-CoA synthetase short-chain family member 1


chr16_+_1203240 0.517 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr17_-_42298228 0.513 NM_001076683
UBTF
upstream binding transcription factor, RNA polymerase I
chr1_+_226250421 0.513 H3F3A
H3F3AP4
H3 histone, family 3A
H3 histone, family 3A, pseudogene 4
chr6_+_19837599 0.511 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr11_+_66045645 0.509 NM_182553
CNIH2
cornichon homolog 2 (Drosophila)
chr19_-_52598965 0.508 NM_001136499
ZNF841
zinc finger protein 841
chr3_-_197676755 0.508 NM_001134435
IQCG
IQ motif containing G
chr17_+_72427535 0.508 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr12_-_39836760 0.507 NM_001173463
NM_001173464
NM_001173465
NM_017641
KIF21A



kinesin family member 21A



chr1_+_226250413 0.505 H3F3A
H3 histone, family 3A
chr12_-_63328663 0.504 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr9_+_127019782 0.502 NM_001166167
NM_001145001
NM_014397
NEK6


NIMA (never in mitosis gene a)-related kinase 6


chr11_+_76777926 0.502 NM_004055
CAPN5
calpain 5
chr2_-_111334677 0.502 NM_005054
RGPD5
RANBP2-like and GRIP domain containing 5
chr17_+_1628032 0.501 NM_001163809
WDR81
WD repeat domain 81
chr14_+_105780751 0.497 NM_001100913
NM_015197
PACS2

phosphofurin acidic cluster sorting protein 2

chr19_+_1491000 0.497 NM_138393
REEP6
receptor accessory protein 6
chr2_+_231902194 0.495 NM_001144994
C2orf72
chromosome 2 open reading frame 72
chr17_+_73521744 0.493 NM_001015002
NM_001031803
NM_004524
LLGL2


lethal giant larvae homolog 2 (Drosophila)


chr11_+_45907198 0.491 MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr13_+_37006408 0.488 NM_001111045
NM_003914
CCNA1

cyclin A1

chr5_-_111093030 0.483 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr12_-_29936685 0.483 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr6_+_52442104 0.482 FLJ37798
uncharacterized LOC401264
chr5_+_56111379 0.480 MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr17_-_5404304 0.480 NM_001162371
LOC728392
uncharacterized LOC728392
chr15_-_27018108 0.478 GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr20_+_60718473 0.477 NM_198935
SS18L1
synovial sarcoma translocation gene on chromosome 18-like 1
chr7_+_129142319 0.477 NM_001195243
LOC100287482
uncharacterized LOC100287482

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.42 2.03e-12 GO:0007399 nervous system development
1.08 6.29e-10 GO:0009987 cellular process
1.32 9.64e-09 GO:0006464 protein modification process
1.29 1.88e-08 GO:0048523 negative regulation of cellular process
1.27 4.13e-08 GO:0048519 negative regulation of biological process
1.21 4.75e-08 GO:0007275 multicellular organismal development
1.24 9.10e-08 GO:0048731 system development
1.44 1.09e-07 GO:0022008 neurogenesis
1.22 1.14e-07 GO:0048856 anatomical structure development
1.29 1.24e-07 GO:0043412 macromolecule modification
1.44 4.07e-07 GO:0048699 generation of neurons
1.31 4.87e-07 GO:0023051 regulation of signaling
1.12 9.36e-07 GO:0050794 regulation of cellular process
1.50 9.47e-07 GO:0007167 enzyme linked receptor protein signaling pathway
1.18 1.59e-06 GO:0032502 developmental process
1.41 2.26e-06 GO:0048468 cell development
1.38 8.08e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.19 8.89e-06 GO:0060255 regulation of macromolecule metabolic process
1.11 1.23e-05 GO:0050789 regulation of biological process
1.49 1.35e-05 GO:0010629 negative regulation of gene expression
1.18 1.36e-05 GO:0080090 regulation of primary metabolic process
1.55 1.40e-05 GO:0006325 chromatin organization
1.35 2.46e-05 GO:0010646 regulation of cell communication
1.44 2.87e-05 GO:0030182 neuron differentiation
1.50 2.97e-05 GO:0051253 negative regulation of RNA metabolic process
1.37 2.98e-05 GO:0009892 negative regulation of metabolic process
1.50 3.46e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.12 3.62e-05 GO:0044237 cellular metabolic process
1.57 3.76e-05 GO:0008285 negative regulation of cell proliferation
1.29 4.06e-05 GO:0009653 anatomical structure morphogenesis
1.10 4.43e-05 GO:0065007 biological regulation
1.47 4.57e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 5.80e-05 GO:0009966 regulation of signal transduction
1.37 9.49e-05 GO:0031324 negative regulation of cellular metabolic process
1.57 1.05e-04 GO:0007264 small GTPase mediated signal transduction
1.50 1.17e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.21 1.25e-04 GO:0010468 regulation of gene expression
1.45 1.27e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.45 1.55e-04 GO:0000902 cell morphogenesis
1.36 1.73e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.16 2.12e-04 GO:0023052 signaling
1.17 2.13e-04 GO:0031323 regulation of cellular metabolic process
1.42 2.28e-04 GO:0045595 regulation of cell differentiation
1.49 2.32e-04 GO:0000904 cell morphogenesis involved in differentiation
1.49 2.57e-04 GO:0007417 central nervous system development
1.55 3.11e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.32 3.85e-04 GO:0010563 negative regulation of phosphorus metabolic process
2.32 3.85e-04 GO:0045936 negative regulation of phosphate metabolic process
1.43 3.90e-04 GO:0032989 cellular component morphogenesis
1.15 5.82e-04 GO:0019222 regulation of metabolic process
1.48 5.92e-04 GO:0031175 neuron projection development
1.40 6.01e-04 GO:0009890 negative regulation of biosynthetic process
1.42 6.90e-04 GO:0030030 cell projection organization
1.65 7.34e-04 GO:0045596 negative regulation of cell differentiation
1.40 7.97e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.14 1.02e-03 GO:0044260 cellular macromolecule metabolic process
1.54 1.25e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.54 1.25e-03 GO:0016568 chromatin modification
1.19 1.28e-03 GO:0044267 cellular protein metabolic process
1.49 1.31e-03 GO:0032583 regulation of gene-specific transcription
1.18 1.33e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20 1.48e-03 GO:0051252 regulation of RNA metabolic process
1.27 1.56e-03 GO:0035556 intracellular signal transduction
1.48 2.56e-03 GO:0048812 neuron projection morphogenesis
1.27 2.70e-03 GO:0051239 regulation of multicellular organismal process
1.48 2.71e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.32 2.75e-03 GO:0042127 regulation of cell proliferation
1.39 2.92e-03 GO:0001932 regulation of protein phosphorylation
1.41 2.95e-03 GO:0048666 neuron development
1.49 3.03e-03 GO:0007409 axonogenesis
2.25 3.06e-03 GO:0042326 negative regulation of phosphorylation
1.54 3.08e-03 GO:0007389 pattern specification process
1.32 3.42e-03 GO:0050793 regulation of developmental process
1.37 3.49e-03 GO:0019220 regulation of phosphate metabolic process
1.37 3.49e-03 GO:0051174 regulation of phosphorus metabolic process
1.38 4.03e-03 GO:0042325 regulation of phosphorylation
1.64 4.10e-03 GO:0003002 regionalization
1.17 4.17e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.64 5.05e-03 GO:0007507 heart development
1.09 5.18e-03 GO:0008152 metabolic process
1.20 5.48e-03 GO:0006355 regulation of transcription, DNA-dependent
1.43 5.60e-03 GO:0048858 cell projection morphogenesis
1.43 5.79e-03 GO:0032990 cell part morphogenesis
1.38 7.18e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.42 7.61e-03 GO:0051338 regulation of transferase activity
1.17 7.71e-03 GO:0071842 cellular component organization at cellular level
1.77 7.71e-03 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
1.53 8.12e-03 GO:0051093 negative regulation of developmental process
1.69 9.17e-03 GO:0048732 gland development
1.71 9.58e-03 GO:0016569 covalent chromatin modification
1.18 1.01e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.37 1.03e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.72 1.05e-02 GO:0016570 histone modification
1.42 1.11e-02 GO:0043549 regulation of kinase activity
1.15 1.34e-02 GO:0016043 cellular component organization
1.67 1.43e-02 GO:0032582 negative regulation of gene-specific transcription
1.35 1.55e-02 GO:0010628 positive regulation of gene expression
1.32 1.71e-02 GO:0031399 regulation of protein modification process
1.31 1.75e-02 GO:0006351 transcription, DNA-dependent
1.19 1.81e-02 GO:0048869 cellular developmental process
1.14 1.92e-02 GO:0007165 signal transduction
1.55 2.22e-02 GO:0061061 muscle structure development
1.54 2.38e-02 GO:0007423 sensory organ development
1.60 3.07e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.36 3.41e-02 GO:0051276 chromosome organization
1.32 3.44e-02 GO:0006468 protein phosphorylation
1.79 3.44e-02 GO:0030111 regulation of Wnt receptor signaling pathway
1.19 3.56e-02 GO:0048513 organ development
1.15 3.63e-02 GO:0019538 protein metabolic process
1.19 3.74e-02 GO:0030154 cell differentiation
1.43 3.98e-02 GO:0040008 regulation of growth
1.17 4.26e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.16 4.33e-02 GO:0031326 regulation of cellular biosynthetic process
1.70 4.58e-02 GO:0009952 anterior/posterior pattern formation
1.16 4.73e-02 GO:0009889 regulation of biosynthetic process
1.51 4.79e-02 GO:0048729 tissue morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 2.85e-12 GO:0044424 intracellular part
1.08 1.09e-11 GO:0005622 intracellular
1.11 6.76e-11 GO:0043227 membrane-bounded organelle
1.11 1.17e-10 GO:0043231 intracellular membrane-bounded organelle
1.09 7.78e-09 GO:0043226 organelle
1.09 1.88e-08 GO:0043229 intracellular organelle
1.03 2.12e-05 GO:0044464 cell part
1.03 2.26e-05 GO:0005623 cell
1.08 1.64e-04 GO:0005737 cytoplasm
1.11 1.82e-04 GO:0005634 nucleus
1.33 2.91e-03 GO:0044451 nucleoplasm part
1.48 4.86e-02 GO:0005667 transcription factor complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.09 3.86e-14 GO:0005488 binding
1.12 9.30e-09 GO:0005515 protein binding
2.90 1.79e-06 GO:0046332 SMAD binding
1.36 2.20e-04 GO:0016301 kinase activity
2.17 2.86e-04 GO:0019199 transmembrane receptor protein kinase activity
1.36 3.74e-04 GO:0019899 enzyme binding
1.31 1.16e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.35 1.18e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.29 1.41e-03 GO:0030528 transcription regulator activity
1.29 1.52e-03 GO:0001071 nucleic acid binding transcription factor activity
1.29 1.52e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.52 3.88e-03 GO:0016564 transcription repressor activity
1.43 4.53e-03 GO:0019904 protein domain specific binding
1.16 1.53e-02 GO:0003677 DNA binding
1.43 1.67e-02 GO:0000988 protein binding transcription factor activity
1.43 1.67e-02 GO:0000989 transcription factor binding transcription factor activity
1.61 1.79e-02 GO:0005244 voltage-gated ion channel activity
1.61 1.79e-02 GO:0022832 voltage-gated channel activity
1.33 2.02e-02 GO:0004672 protein kinase activity
1.42 2.44e-02 GO:0003712 transcription cofactor activity
1.68 3.74e-02 GO:0022843 voltage-gated cation channel activity
1.16 4.56e-02 GO:0000166 nucleotide binding