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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: MYFfamily.p2

Z-value: 1.014

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_-_140715234	1.115	NM_016601	KCNK9	potassium channel, subfamily K, member 9
chr4_+_134073180	1.008		PCDH10	protocadherin 10
chr4_-_16077740	0.985	NM_001145849 NM_001145850 NM_001145851 NM_001145852 NM_006017	PROM1	prominin 1
chr19_-_47734215	0.975	NM_014417	BBC3	BCL2 binding component 3
chr5_-_44388666	0.969	NM_004465	FGF10	fibroblast growth factor 10
chr6_-_91006460	0.934	NM_021813	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr8_-_23712297	0.888	NM_003155	STC1	stanniocalcin 1
chr17_-_39324423	0.868	NM_033187	KRTAP4-3	keratin associated protein 4-3
chr9_-_131940481	0.861		IER5L	immediate early response 5-like
chr13_-_36050758	0.851	NM_005584	MAB21L1	mab-21-like 1 (C. elegans)
chr13_+_36050885	0.838	NM_001204197	NBEA	neurobeachin
chr6_+_99282597	0.811		POU3F2	POU class 3 homeobox 2
chr3_-_124774735	0.778	NM_020733	HEG1	HEG homolog 1 (zebrafish)
chr1_+_47264669	0.771	NM_000779 NM_001099772	CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1
chr16_+_4430878	0.757		VASN	vasorin
chrX_-_99665270	0.743	NM_001105243 NM_001184880 NM_020766	PCDH19	protocadherin 19
chr10_-_13043570	0.742	NM_031455	CCDC3	coiled-coil domain containing 3
chr16_-_74640997	0.677		GLG1	golgi glycoprotein 1
chr20_+_2673193	0.668	NM_001110514	EBF4	early B-cell factor 4
chr4_-_16085309	0.660		PROM1	prominin 1
chrX_-_110513750	0.657	NM_014289	CAPN6	calpain 6
chr6_-_30523502	0.656		GNL1	guanine nucleotide binding protein-like 1
chr16_-_74640915	0.653		GLG1	golgi glycoprotein 1
chr2_-_39187477	0.634		LOC375196	uncharacterized LOC375196
chr17_-_39183453	0.613	NM_031957	KRTAP1-5	keratin associated protein 1-5
chr4_-_174450529	0.591		HAND2	heart and neural crest derivatives expressed 2
chr2_+_121103670	0.585	NM_002193	INHBB	inhibin, beta B
chr6_-_27775683	0.582	NM_003519	HIST1H2BL	histone cluster 1, H2bl
chr2_-_172967627	0.575		DLX2	distal-less homeobox 2
chr11_+_71249070	0.565	NM_021046	KRTAP5-8	keratin associated protein 5-8
chr6_-_91006580	0.563	NM_001170794	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr9_-_131940538	0.562	NM_203434	IER5L	immediate early response 5-like
chr2_+_148778573	0.559	NM_018328	MBD5	methyl-CpG binding domain protein 5
chr16_+_67876381	0.540		THAP11	THAP domain containing 11
chr7_+_145813452	0.538	NM_014141	CNTNAP2	contactin associated protein-like 2
chr7_-_158380360	0.534	NM_002847 NM_130842 NM_130843	PTPRN2	protein tyrosine phosphatase, receptor type, N polypeptide 2
chr2_-_7005764	0.530	NM_207315	CMPK2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr13_-_114567011	0.524		GAS6	growth arrest-specific 6
chr11_-_9113092	0.515	NM_001170690 NM_020974	SCUBE2	signal peptide, CUB domain, EGF-like 2
chr7_+_128828712	0.512	NM_005631	SMO	smoothened, frizzled family receptor
chr11_-_86666089	0.507		FZD4	frizzled family receptor 4
chr1_-_57045214	0.501		PPAP2B	phosphatidic acid phosphatase type 2B
chr14_-_105634708	0.497		JAG2	jagged 2
chr1_-_109656478	0.497	NM_001122961	C1orf194	chromosome 1 open reading frame 194
chr18_-_22931970	0.493		ZNF521	zinc finger protein 521
chr13_-_36705432	0.490		DCLK1	doublecortin-like kinase 1
chr7_-_131241321	0.489	NM_001018111 NM_005397	PODXL	podocalyxin-like
chr16_-_56459371	0.486	NM_001144	AMFR	autocrine motility factor receptor
chr9_-_139948448	0.481	NM_001246 NM_203468	ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2
chr13_-_114567040	0.468	NM_000820	GAS6	growth arrest-specific 6
chr2_+_187558654	0.466	NM_177454	FAM171B	family with sequence similarity 171, member B
chr13_-_114566951	0.465		GAS6	growth arrest-specific 6
chr12_-_112036257	0.462		ATXN2	ataxin 2
chr19_+_41699076	0.455	NM_030622	CYP2S1	cytochrome P450, family 2, subfamily S, polypeptide 1
chr16_-_74641014	0.452	NM_001145666 NM_001145667 NM_012201	GLG1	golgi glycoprotein 1
chr17_-_39296702	0.447	NM_030976	KRTAP4-6	keratin associated protein 4-6
chr2_-_172967234	0.447	NM_004405	DLX2	distal-less homeobox 2
chr11_-_66335958	0.442	NM_003793	CTSF	cathepsin F
chr13_-_114567034	0.440		GAS6	growth arrest-specific 6
chr8_+_56015013	0.439	NM_052898	XKR4	XK, Kell blood group complex subunit-related family, member 4
chr14_-_105635114	0.439	NM_002226 NM_145159	JAG2	jagged 2
chr20_+_2795613	0.434	NM_080739	C20orf141	chromosome 20 open reading frame 141
chr2_+_128458943	0.429		SFT2D3	SFT2 domain containing 3
chr12_+_120427476	0.428	NM_207311	CCDC64	coiled-coil domain containing 64
chr17_-_42297037	0.422	NM_001076684 NM_014233	UBTF	upstream binding transcription factor, RNA polymerase I
chr9_-_139940556	0.422		NPDC1	neural proliferation, differentiation and control, 1
chr7_-_137028275	0.413		PTN	pleiotrophin
chr8_+_104383785	0.411	NM_138455	CTHRC1	collagen triple helix repeat containing 1
chr11_+_65658101	0.402		CCDC85B	coiled-coil domain containing 85B
chr9_-_98270830	0.399	NM_000264	PTCH1	patched 1
chr1_+_155051263	0.399	NM_004952	EFNA3	ephrin-A3
chr20_-_52790511	0.398	NM_000782 NM_001128915	CYP24A1	cytochrome P450, family 24, subfamily A, polypeptide 1
chr3_-_50383009	0.397	NM_015896	ZMYND10	zinc finger, MYND-type containing 10
chr22_-_17602142	0.396	NM_031890 NM_001163079	CECR6	cat eye syndrome chromosome region, candidate 6
chr13_-_110438896	0.391	NM_003749	IRS2	insulin receptor substrate 2
chrX_-_19905605	0.390		SH3KBP1	SH3-domain kinase binding protein 1
chr12_+_53818864	0.387		AMHR2	anti-Mullerian hormone receptor, type II
chr5_-_178772430	0.386	NM_014244 NM_021599	ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr4_-_105412466	0.383	NM_025212	CXXC4	CXXC finger protein 4
chr16_+_725679	0.381		RHBDL1	rhomboid, veinlet-like 1 (Drosophila)
chr17_-_39203423	0.381	NM_001123387	KRTAP2-1	keratin associated protein 2-1
chr5_-_147162251	0.374	NM_014790	JAKMIP2	janus kinase and microtubule interacting protein 2
chr18_-_22932109	0.371	NM_015461	ZNF521	zinc finger protein 521
chr3_-_45267068	0.369		TMEM158	transmembrane protein 158 (gene/pseudogene)
chr6_+_32407618	0.369	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr4_+_186317964	0.369		ANKRD37	ankyrin repeat domain 37
chr5_-_147162175	0.367		JAKMIP2	janus kinase and microtubule interacting protein 2
chr3_+_140770412	0.367		SPSB4	splA/ryanodine receptor domain and SOCS box containing 4
chr2_+_233320832	0.366	NM_001631	ALPI	alkaline phosphatase, intestinal
chr19_+_50192440	0.365		C19orf76	chromosome 19 open reading frame 76
chr6_+_26183957	0.360	NM_003523	HIST1H2BE	histone cluster 1, H2be
chr6_+_26158332	0.359	NM_021063 NM_138720	HIST1H2BD	histone cluster 1, H2bd
chr22_-_30783301	0.357	NM_001017981	RNF215	ring finger protein 215
chr6_-_132272311	0.357	NM_001901	CTGF	connective tissue growth factor
chr16_+_69726751	0.354		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr8_+_104383701	0.353		CTHRC1	collagen triple helix repeat containing 1
chr6_+_157099873	0.353		ARID1B	AT rich interactive domain 1B (SWI1-like)
chr10_-_133109983	0.351	NM_174937	TCERG1L	transcription elongation regulator 1-like
chr12_-_71003622	0.351	NM_001206971 NM_001206972 NM_002837	PTPRB	protein tyrosine phosphatase, receptor type, B
chr14_-_54423448	0.350	NM_001202 NM_130850	BMP4	bone morphogenetic protein 4
chr22_-_31503484	0.345	NM_080430	SELM	selenoprotein M
chr11_+_71710971	0.342	NM_001145055	IL18BP	interleukin 18 binding protein
chr17_-_42296923	0.338		UBTF	upstream binding transcription factor, RNA polymerase I
chr9_-_84304378	0.336		TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr11_+_76813884	0.336	NM_006189	OMP	olfactory marker protein
chr5_-_148033715	0.335	NM_000870	HTR4	5-hydroxytryptamine (serotonin) receptor 4
chr1_-_57044980	0.335		PPAP2B	phosphatidic acid phosphatase type 2B
chr3_-_165555167	0.334		BCHE	butyrylcholinesterase
chr6_+_157099203	0.333
chr5_+_99871023	0.330	NM_198507	FAM174A	family with sequence similarity 174, member A
chr16_+_29823557	0.327		PRRT2	proline-rich transmembrane protein 2
chr17_-_7518124	0.326	NM_004860	FXR2	fragile X mental retardation, autosomal homolog 2
chr6_-_32908583	0.326	NM_002118	HLA-DMB	major histocompatibility complex, class II, DM beta
chr8_+_85095452	0.324	NM_001100392 NM_001100393	RALYL	RALY RNA binding protein-like
chr3_+_110790460	0.324	NM_001243286 NM_015480	PVRL3	poliovirus receptor-related 3
chr5_-_147162056	0.322		JAKMIP2	janus kinase and microtubule interacting protein 2
chr20_+_19193364	0.322		SLC24A3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr18_+_77659446	0.320
chr9_-_139940464	0.320		NPDC1	neural proliferation, differentiation and control, 1
chr5_-_138725544	0.318	NM_016459	MZB1	marginal zone B and B1 cell-specific protein
chr1_-_57045129	0.317		PPAP2B	phosphatidic acid phosphatase type 2B
chr3_-_4508955	0.316	NM_001164674 NM_001164675 NM_182760	SUMF1	sulfatase modifying factor 1
chr2_-_230579198	0.316	NM_139072	DNER	delta/notch-like EGF repeat containing
chr2_-_190445466	0.315		SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1
chr19_+_3094528	0.315		GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr19_+_18284631	0.311		IFI30	interferon, gamma-inducible protein 30
chr2_+_115199898	0.311	NM_020868	DPP10	dipeptidyl-peptidase 10 (non-functional)
chr11_+_57365577	0.307	NM_001032295	SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr19_+_41103055	0.306	NM_001042544	LTBP4	latent transforming growth factor beta binding protein 4
chr2_-_190445521	0.306	NM_014585	SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1
chr13_+_78271820	0.305	NM_001242868	SLAIN1	SLAIN motif family, member 1
chr6_+_31973358	0.305	NM_000500 NM_001128590	CYP21A2	cytochrome P450, family 21, subfamily A, polypeptide 2
chr1_-_154842725	0.305	NM_001204087 NM_002249	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr1_-_67390413	0.304	NM_024763 NM_207014	WDR78	WD repeat domain 78
chr20_+_62368035	0.303		LIME1	Lck interacting transmembrane adaptor 1
chr4_+_7194317	0.302	NM_020777	SORCS2	sortilin-related VPS10 domain containing receptor 2
chr18_-_500583	0.300	NM_130386	COLEC12	collectin sub-family member 12
chr22_-_18923654	0.300		PRODH	proline dehydrogenase (oxidase) 1
chr1_-_57045235	0.297	NM_003713	PPAP2B	phosphatidic acid phosphatase type 2B
chr11_-_106888829	0.297	NM_000855	GUCY1A2	guanylate cyclase 1, soluble, alpha 2
chr2_-_220436010	0.292		OBSL1	obscurin-like 1
chr16_-_75590107	0.290	NM_001077416 NM_001077418 NM_001077419	TMEM231	transmembrane protein 231
chr11_+_61976139	0.289	NM_002407	SCGB2A1	secretoglobin, family 2A, member 1
chrX_-_47489243	0.288	NM_001145252	CFP	complement factor properdin
chr2_-_190445612	0.288		SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1
chrX_-_140271275	0.288		LDOC1	leucine zipper, down-regulated in cancer 1
chr9_-_139940595	0.288	NM_015392	NPDC1	neural proliferation, differentiation and control, 1
chr1_+_218519576	0.287		TGFB2	transforming growth factor, beta 2
chrX_-_38079980	0.285	NM_001170750 NM_001170751 NM_001170752 NM_006307	SRPX	sushi-repeat containing protein, X-linked
chr16_+_2802683	0.284		SRRM2	serine/arginine repetitive matrix 2
chr9_+_137533713	0.283		COL5A1	collagen, type V, alpha 1
chr2_+_79740059	0.282	NM_001164883 NM_004389	CTNNA2	catenin (cadherin-associated protein), alpha 2
chr19_-_12845539	0.281		C19orf43	chromosome 19 open reading frame 43
chr20_+_62367945	0.280	NM_017806	LIME1	Lck interacting transmembrane adaptor 1
chr8_-_33457491	0.279		DUSP26	dual specificity phosphatase 26 (putative)
chr15_-_61521416	0.278		RORA	RAR-related orphan receptor A
chr4_+_3768104	0.278		ADRA2C	adrenergic, alpha-2C-, receptor
chr9_-_35812143	0.278	NM_001039592 NM_172312	SPAG8	sperm associated antigen 8
chr11_-_33891361	0.277	NM_001142316	LMO2	LIM domain only 2 (rhombotin-like 1)
chr6_+_157099041	0.277	NM_017519 NM_020732	ARID1B	AT rich interactive domain 1B (SWI1-like)
chr8_+_65493610	0.276		BHLHE22	basic helix-loop-helix family, member e22
chr19_+_41699140	0.274		CYP2S1	cytochrome P450, family 2, subfamily S, polypeptide 1
chr16_-_67427335	0.272	NM_015964 NM_016140	TPPP3	tubulin polymerization-promoting protein family member 3
chr6_+_73331992	0.272		KCNQ5	potassium voltage-gated channel, KQT-like subfamily, member 5
chr15_-_56035176	0.271	NM_173814	PRTG	protogenin
chr3_-_165555252	0.270	NM_000055	BCHE	butyrylcholinesterase
chr15_-_27018216	0.268	NM_000814	GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3
chrX_-_140271293	0.267	NM_012317	LDOC1	leucine zipper, down-regulated in cancer 1
chr20_+_56725982	0.267	NM_178456	C20orf85	chromosome 20 open reading frame 85
chr7_-_45960738	0.266	NM_000598 NM_001013398	IGFBP3	insulin-like growth factor binding protein 3
chr12_+_26348488	0.266	NM_005086	SSPN	sarcospan (Kras oncogene-associated gene)
chr17_-_42296865	0.266		UBTF	upstream binding transcription factor, RNA polymerase I
chr11_-_33891485	0.264	NM_001142315	LMO2	LIM domain only 2 (rhombotin-like 1)
chr20_-_23066828	0.264	NM_012072	CD93	CD93 molecule
chr9_-_34381497	0.263	NM_001252195 NM_147168 NM_147169	C9orf24	chromosome 9 open reading frame 24
chr18_+_56530677	0.263		ZNF532	zinc finger protein 532
chr4_+_89299874	0.263	NM_001165136 NM_017912	HERC6	hect domain and RLD 6
chr15_+_96873845	0.262	NM_021005	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr12_-_112037024	0.260		ATXN2	ataxin 2
chr19_-_7701852	0.259
chr19_+_18284578	0.259	NM_006332	IFI30	interferon, gamma-inducible protein 30
chrX_-_128788913	0.259	NM_017413	APLN	apelin
chr10_+_12391728	0.255		CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr11_+_64001974	0.254	NM_001243733 NM_003377	VEGFB	vascular endothelial growth factor B
chr1_-_58716173	0.254		DAB1	disabled homolog 1 (Drosophila)
chr18_-_46477080	0.253	NM_001190821 NM_005904	SMAD7	SMAD family member 7
chr11_-_33891258	0.253		LMO2	LIM domain only 2 (rhombotin-like 1)
chr2_-_220436267	0.252	NM_001173408 NM_001173431 NM_015311	OBSL1	obscurin-like 1
chr15_-_37391596	0.251	NM_172316	MEIS2	Meis homeobox 2
chr4_+_89300110	0.251		HERC6	hect domain and RLD 6
chr4_+_15005364	0.250		CPEB2	cytoplasmic polyadenylation element binding protein 2
chr6_-_30523933	0.250		GNL1	guanine nucleotide binding protein-like 1
chrX_-_103087106	0.246	NM_016370	RAB9B	RAB9B, member RAS oncogene family
chr7_+_153749740	0.245	NM_130797	DPP6	dipeptidyl-peptidase 6
chr6_-_111136330	0.243		CDK19	cyclin-dependent kinase 19
chr1_-_54519050	0.243	NM_004872	TMEM59	transmembrane protein 59
chr16_+_2802634	0.243		SRRM2	serine/arginine repetitive matrix 2
chr6_-_111136407	0.242	NM_015076	CDK19	cyclin-dependent kinase 19
chrX_-_19905665	0.242	NM_031892	SH3KBP1	SH3-domain kinase binding protein 1
chr1_-_54518790	0.241		TMEM59	transmembrane protein 59

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.24	3.27e-09	GO:0007275	multicellular organismal development
1.23	3.48e-09	GO:0023052	signaling
1.27	4.34e-09	GO:0048731	system development
1.22	5.77e-09	GO:0032502	developmental process
1.56	1.44e-08	GO:0007155	cell adhesion
1.56	1.44e-08	GO:0022610	biological adhesion
1.24	2.51e-08	GO:0048856	anatomical structure development
1.22	2.97e-07	GO:0007165	signal transduction
1.31	1.23e-06	GO:0007166	cell surface receptor linked signaling pathway
1.44	3.00e-06	GO:0048468	cell development
1.33	1.39e-05	GO:0007399	nervous system development
1.11	2.95e-05	GO:0065007	biological regulation
1.32	2.97e-05	GO:0009653	anatomical structure morphogenesis
1.36	2.33e-04	GO:0010646	regulation of cell communication
1.40	3.09e-04	GO:0048699	generation of neurons
1.10	3.72e-04	GO:0050789	regulation of biological process
1.46	3.75e-04	GO:0007167	enzyme linked receptor protein signaling pathway
1.25	7.02e-04	GO:0048513	organ development
1.11	7.78e-04	GO:0050794	regulation of cellular process
1.43	8.62e-04	GO:0030182	neuron differentiation
1.35	9.25e-04	GO:0032879	regulation of localization
1.26	1.57e-03	GO:0023051	regulation of signaling
1.36	1.67e-03	GO:0022008	neurogenesis
1.13	1.96e-03	GO:0032501	multicellular organismal process
1.22	3.06e-03	GO:0065008	regulation of biological quality
1.44	4.90e-03	GO:0048666	neuron development
1.62	6.82e-03	GO:0051270	regulation of cellular component movement
1.58	9.35e-03	GO:0001501	skeletal system development
1.14	1.12e-02	GO:0051716	cellular response to stimulus
1.21	1.31e-02	GO:0030154	cell differentiation
1.20	1.66e-02	GO:0048869	cellular developmental process
1.45	1.73e-02	GO:0000904	cell morphogenesis involved in differentiation
2.20	1.86e-02	GO:0022612	gland morphogenesis
1.40	2.04e-02	GO:0009725	response to hormone stimulus
1.83	2.32e-02	GO:0046883	regulation of hormone secretion
1.94	2.86e-02	GO:0050796	regulation of insulin secretion
1.40	2.91e-02	GO:0000902	cell morphogenesis
1.56	3.40e-02	GO:0016337	cell-cell adhesion
1.90	3.51e-02	GO:0002791	regulation of peptide secretion
1.90	3.51e-02	GO:0090087	regulation of peptide transport
1.43	3.63e-02	GO:0001775	cell activation
1.57	4.08e-02	GO:0040012	regulation of locomotion
1.32	4.17e-02	GO:0040011	locomotion
1.36	4.51e-02	GO:0045595	regulation of cell differentiation
1.59	4.96e-02	GO:2000145	regulation of cell motility

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.30	3.35e-09	GO:0044459	plasma membrane part
1.29	5.48e-08	GO:0005576	extracellular region
1.39	2.15e-06	GO:0044421	extracellular region part
1.66	2.19e-06	GO:0031012	extracellular matrix
1.16	2.96e-05	GO:0005886	plasma membrane
1.10	3.14e-05	GO:0016020	membrane
1.15	7.00e-05	GO:0071944	cell periphery
1.11	1.06e-04	GO:0044425	membrane part
1.30	1.81e-04	GO:0031226	intrinsic to plasma membrane
1.61	2.92e-04	GO:0005578	proteinaceous extracellular matrix
1.29	5.70e-04	GO:0005887	integral to plasma membrane
1.12	6.91e-04	GO:0031224	intrinsic to membrane
1.35	1.71e-03	GO:0005615	extracellular space
1.11	5.19e-03	GO:0016021	integral to membrane
1.29	2.64e-02	GO:0005626	insoluble fraction
1.25	2.87e-02	GO:0005783	endoplasmic reticulum
1.51	4.02e-02	GO:0000323	lytic vacuole
1.51	4.02e-02	GO:0005764	lysosome
1.41	4.16e-02	GO:0045202	synapse
1.29	4.31e-02	GO:0031982	vesicle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.06	7.48e-04	GO:0019838	growth factor binding
1.09	3.11e-03	GO:0005515	protein binding
1.38	3.76e-03	GO:0005509	calcium ion binding
2.92	1.31e-02	GO:0005158	insulin receptor binding
1.28	1.31e-02	GO:0005102	receptor binding
2.14	2.68e-02	GO:0030165	PDZ domain binding
2.02	2.88e-02	GO:0019199	transmembrane receptor protein kinase activity