Motif ID: MZF1.p2

Z-value: 1.150


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_59084928-0.271.4e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_51487070 3.792 NM_139277
NM_001207053
NM_001243126
NM_005046
KLK7



kallikrein-related peptidase 7



chr19_-_55658310 3.448 TNNT1
troponin T type 1 (skeletal, slow)
chr14_-_23834417 2.096 EFS
embryonal Fyn-associated substrate
chr19_-_51472003 2.006 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr2_-_216300770 1.865 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr14_-_23834378 1.804 EFS
embryonal Fyn-associated substrate
chr6_-_30655078 1.630 NM_001134870
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr19_-_51504799 1.550 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr17_+_70117177 1.526 SOX9
SRY (sex determining region Y)-box 9
chr17_+_70117154 1.471 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr6_-_30654978 1.383 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr1_+_205473768 1.377 CDK18
cyclin-dependent kinase 18
chr11_+_5617330 1.345 NM_058166
TRIM6
tripartite motif containing 6
chr1_-_155948206 1.317 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr1_+_205473683 1.301 NM_002596
NM_212502
NM_212503
CDK18


cyclin-dependent kinase 18


chr7_-_149470294 1.262 NM_207336
ZNF467
zinc finger protein 467
chr14_+_24867926 1.251 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr5_-_127873734 1.230 NM_001999
FBN2
fibrillin 2
chr17_+_70117168 1.210 SOX9
SRY (sex determining region Y)-box 9
chr5_+_92918924 1.209 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr19_-_51472816 1.178 NM_002774
KLK6
kallikrein-related peptidase 6
chr19_+_54371150 1.143 MYADM
myeloid-associated differentiation marker
chr17_+_29058653 1.107 SUZ12P
suppressor of zeste 12 homolog pseudogene
chr12_+_6937570 1.091 NM_014262
LEPREL2
leprecan-like 2
chr19_-_51568323 1.040 NM_015596
KLK13
kallikrein-related peptidase 13
chr7_-_23509972 1.035 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr12_+_53491448 1.026 IGFBP6
insulin-like growth factor binding protein 6
chr11_-_71752099 1.023 NUMA1
nuclear mitotic apparatus protein 1
chr7_-_98030165 1.019 BAIAP2L1
BAI1-associated protein 2-like 1
chr6_+_37137882 1.016 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr2_-_165477986 1.001 GRB14
growth factor receptor-bound protein 14
chr19_-_41859830 0.996 NM_000660
TGFB1
transforming growth factor, beta 1
chr12_+_53491417 0.980 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr2_+_228678556 0.951 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr4_+_37892698 0.928 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr17_-_46622274 0.923 NM_002145
HOXB2
homeobox B2
chr9_+_33817168 0.918 NM_017811
UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr8_+_86376130 0.916 NM_000067
CA2
carbonic anhydrase II
chr3_-_53290099 0.915 NM_001064
NM_001135055
TKT

transketolase

chrX_-_100914816 0.913 NM_014782
NM_177949
ARMCX2

armadillo repeat containing, X-linked 2

chr19_+_41725098 0.904 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chr12_-_125348422 0.898 NM_001082959
NM_005505
SCARB1

scavenger receptor class B, member 1

chr19_-_41859519 0.894 TGFB1
transforming growth factor, beta 1
chr12_-_6798528 0.890 NM_133476
ZNF384
zinc finger protein 384
chr20_-_22564893 0.887 FOXA2
forkhead box A2
chr19_-_55720812 0.884 NM_001161440
NM_002842
PTPRH

protein tyrosine phosphatase, receptor type, H

chr11_-_64410785 0.880 NM_138734
NRXN2
neurexin 2
chr12_-_125348266 0.865 SCARB1
scavenger receptor class B, member 1
chr22_+_38071612 0.841 NM_002305
LGALS1
lectin, galactoside-binding, soluble, 1
chr17_+_39969205 0.832 FKBP10
FK506 binding protein 10, 65 kDa
chr14_+_24838301 0.830 NM_001198966
NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr8_+_30241943 0.829 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr19_-_41859253 0.822 TGFB1
transforming growth factor, beta 1
chr19_-_47975244 0.822 NM_015063
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr9_+_133971902 0.819 AIF1L
allograft inflammatory factor 1-like
chr6_-_42419782 0.812 NM_033502
TRERF1
transcriptional regulating factor 1
chr8_+_21900389 0.809 NM_003867
FGF17
fibroblast growth factor 17
chr19_-_41859332 0.800 TGFB1
transforming growth factor, beta 1
chr14_-_23834841 0.787 NM_005864
NM_032459
EFS

embryonal Fyn-associated substrate

chr11_-_62314199 0.785 AHNAK
AHNAK nucleoprotein
chr7_-_143059696 0.779 NM_001031690
FAM131B
family with sequence similarity 131, member B
chr8_+_22022644 0.777 NM_001199
NM_006129
BMP1

bone morphogenetic protein 1

chr1_+_182992329 0.768 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr5_-_151066445 0.765 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr17_+_37895023 0.759 NM_001242442
GRB7
growth factor receptor-bound protein 7
chr17_-_76921076 0.758 TIMP2
TIMP metallopeptidase inhibitor 2
chr2_+_115919512 0.758 NM_001178034
NM_001004360
DPP10

dipeptidyl-peptidase 10 (non-functional)

chr12_-_6798619 0.757 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chr17_+_39968961 0.751 NM_021939
FKBP10
FK506 binding protein 10, 65 kDa
chr10_+_17270469 0.750 VIM
vimentin
chr19_+_39687600 0.750 NM_001001414
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr18_-_22932109 0.743 NM_015461
ZNF521
zinc finger protein 521
chr19_-_54984341 0.740 NM_145057
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr6_-_30523933 0.735 GNL1
guanine nucleotide binding protein-like 1
chr12_+_70759974 0.735 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr20_-_62103815 0.734 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr10_+_17270257 0.732 NM_003380
VIM
vimentin
chr17_+_40913233 0.732 RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr1_-_150780705 0.729 NM_000396
CTSK
cathepsin K
chr6_-_32119717 0.727 NM_030651
PRRT1
proline-rich transmembrane protein 1
chr10_+_102505337 0.718 NM_000278
NM_003987
NM_003988
NM_003989
NM_003990
PAX2




paired box 2




chr2_+_45169036 0.718 NM_005413
SIX3
SIX homeobox 3
chr19_-_11689591 0.716 NM_001111034
ACP5
acid phosphatase 5, tartrate resistant
chr7_-_23509631 0.715


chr19_+_35645614 0.713 NM_014164
FXYD5
FXYD domain containing ion transport regulator 5
chr17_+_2680349 0.708 RAP1GAP2
RAP1 GTPase activating protein 2
chr10_-_121302149 0.704 NM_001005339
RGS10
regulator of G-protein signaling 10
chr16_+_55512801 0.702 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr12_+_57522247 0.701 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr19_+_35645640 0.700 NM_144779
NM_001164605
FXYD5

FXYD domain containing ion transport regulator 5

chr1_+_211432726 0.699 RCOR3
REST corepressor 3
chr6_+_163835668 0.687 NM_006775
NM_206853
NM_206854
NM_206855
QKI



QKI, KH domain containing, RNA binding



chr17_+_37894161 0.686 NM_005310
GRB7
growth factor receptor-bound protein 7
chr9_+_133971862 0.686 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr1_+_182992694 0.685


chr21_+_34442446 0.683 NM_138983
OLIG1
oligodendrocyte transcription factor 1
chr17_-_71640226 0.671 NM_001144952
SDK2
sidekick cell adhesion molecule 2
chr6_-_168377618 0.669 NM_001129895
HGC6.3
uncharacterized LOC100128124
chr11_+_57365577 0.667 NM_001032295
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr8_+_22022677 0.663 BMP1
bone morphogenetic protein 1
chr11_+_5617864 0.658 NM_001003818
NM_001198644
NM_001198645
NM_001003819
TRIM6


TRIM6-TRIM34
tripartite motif containing 6


TRIM6-TRIM34 readthrough
chr19_+_54371170 0.656 MYADM
myeloid-associated differentiation marker
chr20_-_44540685 0.654 PLTP
phospholipid transfer protein
chr1_-_103573894 0.654 COL11A1
collagen, type XI, alpha 1
chr6_-_30652434 0.643 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr4_-_73434467 0.638 NM_014243
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chrX_-_107019001 0.637 NM_198057
TSC22D3
TSC22 domain family, member 3
chr17_+_39969200 0.631 FKBP10
FK506 binding protein 10, 65 kDa
chr11_-_2159472 0.631 IGF2
insulin-like growth factor 2 (somatomedin A)
chr19_-_47975074 0.630 SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr9_-_34589679 0.628 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr18_+_19749403 0.628 NM_005257
GATA6
GATA binding protein 6
chr11_-_60719116 0.627 NM_016582
SLC15A3
solute carrier family 15, member 3
chr15_-_74495528 0.620 NM_001142618
STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr5_-_151066492 0.616 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr1_+_6673744 0.615 NM_153812
PHF13
PHD finger protein 13
chr3_-_112359251 0.611 CCDC80
coiled-coil domain containing 80
chr1_+_214161279 0.610 PROX1
prospero homeobox 1
chr8_+_22462267 0.609 KIAA1967
KIAA1967
chr20_-_21494663 0.609 NM_002509
NKX2-2
NK2 homeobox 2
chr12_-_125348346 0.609 SCARB1
scavenger receptor class B, member 1
chr16_-_58231641 0.607 NM_001896
CSNK2A2
casein kinase 2, alpha prime polypeptide
chr6_-_32119667 0.605 PRRT1
proline-rich transmembrane protein 1
chr11_-_72385411 0.605 NM_002599
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr2_-_72374919 0.603 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr1_-_93426998 0.599 NM_001006605
NM_001252269
NM_001252270
NM_001252273
FAM69A



family with sequence similarity 69, member A



chr17_-_40828441 0.597 NM_024927
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr15_-_74502045 0.597 NM_001199040
STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr2_-_216300444 0.596 FN1
fibronectin 1
chr19_-_51845377 0.595 NM_001163922
VSIG10L
V-set and immunoglobulin domain containing 10 like
chr12_-_53625834 0.591 NM_000966
NM_001243730
NM_001243731
RARG


retinoic acid receptor, gamma


chr1_+_155147051 0.590 TRIM46
tripartite motif containing 46
chr11_+_43963809 0.590 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr11_-_2158510 0.590 IGF2
insulin-like growth factor 2 (somatomedin A)
chr9_+_128509616 0.586 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr20_+_3776905 0.586 CDC25B
cell division cycle 25 homolog B (S. pombe)
chr21_+_40177847 0.581 NM_005239
ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr2_-_165477818 0.581 GRB14
growth factor receptor-bound protein 14
chr19_+_50016606 0.578 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr19_-_49339667 0.575 HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr14_-_24047428 0.572 JPH4
junctophilin 4
chr7_+_24612714 0.568 NM_016447
MPP6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr11_-_2170792 0.564 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr1_-_204120909 0.563 ETNK2
ethanolamine kinase 2
chr19_-_45996470 0.561 NM_206901
RTN2
reticulon 2
chr11_+_76745434 0.560 NM_138706
B3GNT6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
chr19_+_54372659 0.557 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr6_+_15245702 0.554 JARID2
jumonji, AT rich interactive domain 2
chr9_-_116061319 0.553 NM_145051
RNF183
ring finger protein 183
chr3_-_13921617 0.550 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chr12_-_12715244 0.549 NM_030640
DUSP16
dual specificity phosphatase 16
chr1_+_184356186 0.548 C1orf21
chromosome 1 open reading frame 21
chr19_-_19052032 0.548 NM_004838
HOMER3
homer homolog 3 (Drosophila)
chr14_-_94595915 0.543 IFI27L2
interferon, alpha-inducible protein 27-like 2
chr9_+_125137600 0.541 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_-_20812727 0.541 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr3_+_154797644 0.541 NM_007287
MME
membrane metallo-endopeptidase
chr19_-_55660557 0.539 NM_001126132
NM_001126133
NM_003283
TNNT1


troponin T type 1 (skeletal, slow)


chr14_-_94595925 0.538 NM_032036
IFI27L2
interferon, alpha-inducible protein 27-like 2
chr17_+_60705042 0.537 MRC2
mannose receptor, C type 2
chr12_+_56915587 0.535 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr1_-_11714738 0.533 NM_012168
FBXO2
F-box protein 2
chr12_-_118406027 0.529 NM_173598
KSR2
kinase suppressor of ras 2
chr9_-_34590137 0.524 NM_001207011
CNTFR
ciliary neurotrophic factor receptor
chr21_+_40177754 0.523 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr5_+_176560882 0.523 NSD1
nuclear receptor binding SET domain protein 1
chr17_-_40913134 0.522 LOC100190938
uncharacterized LOC100190938
chr9_+_116327301 0.522 NM_134427
RGS3
regulator of G-protein signaling 3
chr19_+_54371125 0.521 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr5_-_159546389 0.516 NM_001130864
NM_052927
PWWP2A

PWWP domain containing 2A

chr1_+_211432732 0.515 RCOR3
REST corepressor 3
chr13_-_44361032 0.512 NM_001242863
NM_017993
ENOX1

ecto-NOX disulfide-thiol exchanger 1

chr19_-_44285012 0.512 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr17_+_40811261 0.512 NM_016437
TUBG2
tubulin, gamma 2
chr12_+_1800146 0.510 ADIPOR2
adiponectin receptor 2
chr11_+_57365026 0.509 NM_000062
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr19_+_54926604 0.508 NM_001005367
NM_001201461
NM_020659
TTYH1


tweety homolog 1 (Drosophila)


chr9_+_34179058 0.507 UBAP1
ubiquitin associated protein 1
chr1_+_167599329 0.507 NM_052862
RCSD1
RCSD domain containing 1
chr8_-_60031545 0.506 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr6_-_30654406 0.505 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr19_+_41082792 0.505 SHKBP1
SH3KBP1 binding protein 1
chr19_+_54926721 0.505 TTYH1
tweety homolog 1 (Drosophila)
chr14_-_24047993 0.504 NM_001146028
NM_032452
JPH4

junctophilin 4

chr11_-_119187811 0.504 NM_006500
MCAM
melanoma cell adhesion molecule
chr14_-_48144156 0.502 NM_001113498
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr7_-_107643330 0.502 NM_002291
LAMB1
laminin, beta 1
chr11_-_123065988 0.501 NM_024769
CLMP
CXADR-like membrane protein
chr16_-_84651519 0.495 COTL1
coactosin-like 1 (Dictyostelium)
chr10_+_99473478 0.495 MARVELD1
MARVEL domain containing 1
chr2_+_210288668 0.494 NM_001039538
MAP2
microtubule-associated protein 2
chr9_-_107690526 0.494 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr1_+_27320132 0.492 NM_001013642
TRNP1
TMF1-regulated nuclear protein 1
chr1_+_214161859 0.491 NM_002763
PROX1
prospero homeobox 1
chr20_+_62328068 0.491 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr1_-_20812271 0.491 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_+_50016500 0.490 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr17_-_36904545 0.487 NM_007144
PCGF2
polycomb group ring finger 2
chr9_+_41500678 0.485 NM_015667
NM_001113541
FAM75A7
FAM75A5
family with sequence similarity 75, member A7
family with sequence similarity 75, member A5
chr1_+_156863522 0.485 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.09 4.30e-24 GO:0009987 cellular process
1.15 1.64e-23 GO:0050794 regulation of cellular process
1.13 3.81e-22 GO:0065007 biological regulation
1.14 1.09e-21 GO:0050789 regulation of biological process
1.20 1.77e-15 GO:0023052 signaling
1.24 9.26e-15 GO:0048518 positive regulation of biological process
1.24 1.03e-13 GO:0048522 positive regulation of cellular process
1.18 1.37e-11 GO:0031323 regulation of cellular metabolic process
1.18 1.40e-11 GO:0080090 regulation of primary metabolic process
1.30 2.48e-11 GO:0007399 nervous system development
1.18 2.94e-11 GO:0060255 regulation of macromolecule metabolic process
1.18 4.96e-11 GO:0007165 signal transduction
1.23 1.11e-10 GO:0048523 negative regulation of cellular process
1.22 1.67e-10 GO:0048519 negative regulation of biological process
1.14 3.49e-10 GO:0043170 macromolecule metabolic process
1.15 5.22e-10 GO:0051716 cellular response to stimulus
1.26 6.58e-10 GO:0023051 regulation of signaling
1.16 6.98e-10 GO:0032502 developmental process
1.15 7.89e-10 GO:0044260 cellular macromolecule metabolic process
1.17 9.94e-10 GO:0007275 multicellular organismal development
1.34 1.49e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.15 1.82e-09 GO:0019222 regulation of metabolic process
1.35 2.25e-09 GO:0022008 neurogenesis
1.36 4.86e-09 GO:0048699 generation of neurons
1.20 4.92e-09 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.17 6.04e-09 GO:0048856 anatomical structure development
1.18 9.40e-09 GO:0048731 system development
1.19 2.69e-08 GO:0031326 regulation of cellular biosynthetic process
1.30 2.96e-08 GO:0010604 positive regulation of macromolecule metabolic process
1.18 3.51e-08 GO:0009889 regulation of biosynthetic process
1.28 3.95e-08 GO:0009893 positive regulation of metabolic process
1.18 4.45e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.19 5.51e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.19 6.46e-08 GO:0010468 regulation of gene expression
1.18 6.90e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20 7.87e-08 GO:0051252 regulation of RNA metabolic process
1.25 8.38e-08 GO:0009653 anatomical structure morphogenesis
1.21 1.70e-07 GO:0030154 cell differentiation
1.33 2.08e-07 GO:0006351 transcription, DNA-dependent
1.15 2.83e-07 GO:0071840 cellular component organization or biogenesis
1.15 3.22e-07 GO:0016043 cellular component organization
1.28 3.31e-07 GO:0031325 positive regulation of cellular metabolic process
1.37 4.11e-07 GO:0051254 positive regulation of RNA metabolic process
1.10 4.39e-07 GO:0044237 cellular metabolic process
1.37 5.08e-07 GO:0010628 positive regulation of gene expression
1.20 6.06e-07 GO:0048869 cellular developmental process
1.30 6.88e-07 GO:0007154 cell communication
1.09 8.57e-07 GO:0008152 metabolic process
1.34 9.98e-07 GO:2000026 regulation of multicellular organismal development
1.24 1.01e-06 GO:0009966 regulation of signal transduction
1.38 1.03e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.10 1.37e-06 GO:0044238 primary metabolic process
1.31 1.45e-06 GO:0050793 regulation of developmental process
1.19 1.50e-06 GO:0006355 regulation of transcription, DNA-dependent
1.35 1.96e-06 GO:0030182 neuron differentiation
1.33 2.21e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
1.33 3.27e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 3.79e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
1.31 5.40e-06 GO:0031328 positive regulation of cellular biosynthetic process
1.31 5.49e-06 GO:0009891 positive regulation of biosynthetic process
1.24 7.11e-06 GO:0051239 regulation of multicellular organismal process
1.20 7.49e-06 GO:0048583 regulation of response to stimulus
1.29 8.95e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.28 1.03e-05 GO:0009892 negative regulation of metabolic process
1.32 1.26e-05 GO:0007267 cell-cell signaling
1.29 1.76e-05 GO:0031324 negative regulation of cellular metabolic process
1.13 2.05e-05 GO:0051179 localization
1.18 2.58e-05 GO:0065008 regulation of biological quality
1.19 2.79e-05 GO:0006464 protein modification process
1.15 3.01e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 3.43e-05 GO:0010646 regulation of cell communication
1.30 3.69e-05 GO:0051128 regulation of cellular component organization
1.35 4.38e-05 GO:0048666 neuron development
1.20 5.76e-05 GO:0016070 RNA metabolic process
1.14 8.03e-05 GO:0006810 transport
1.19 9.15e-05 GO:0010467 gene expression
1.32 1.12e-04 GO:0045595 regulation of cell differentiation
1.27 1.54e-04 GO:0048468 cell development
1.31 1.62e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.31 1.65e-04 GO:0009890 negative regulation of biosynthetic process
1.26 1.71e-04 GO:0032774 RNA biosynthetic process
1.36 1.99e-04 GO:0031175 neuron projection development
1.32 2.12e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.14 2.32e-04 GO:0051234 establishment of localization
1.32 2.41e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16 2.51e-04 GO:0090304 nucleic acid metabolic process
1.34 2.72e-04 GO:0051253 negative regulation of RNA metabolic process
1.36 3.40e-04 GO:0019226 transmission of nerve impulse
1.36 3.40e-04 GO:0035637 multicellular organismal signaling
1.25 3.53e-04 GO:0006793 phosphorus metabolic process
1.25 3.53e-04 GO:0006796 phosphate metabolic process
1.17 3.68e-04 GO:0043412 macromolecule modification
1.30 3.84e-04 GO:0009790 embryo development
1.29 4.20e-04 GO:0006468 protein phosphorylation
1.31 4.48e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.34 4.68e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.31 4.70e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.35 5.69e-04 GO:0000904 cell morphogenesis involved in differentiation
1.44 7.53e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.37 7.72e-04 GO:0007268 synaptic transmission
1.13 8.73e-04 GO:0034641 cellular nitrogen compound metabolic process
1.31 9.54e-04 GO:0010629 negative regulation of gene expression
1.34 1.03e-03 GO:0007417 central nervous system development
1.36 1.31e-03 GO:0051094 positive regulation of developmental process
1.27 1.36e-03 GO:0016192 vesicle-mediated transport
1.38 1.90e-03 GO:0007264 small GTPase mediated signal transduction
1.35 2.00e-03 GO:0048812 neuron projection morphogenesis
1.42 2.15e-03 GO:0060284 regulation of cell development
1.22 2.30e-03 GO:0051246 regulation of protein metabolic process
1.29 2.37e-03 GO:0030030 cell projection organization
1.12 3.61e-03 GO:0006807 nitrogen compound metabolic process
1.23 4.78e-03 GO:0032879 regulation of localization
1.34 6.34e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.16 6.35e-03 GO:0007166 cell surface receptor linked signaling pathway
1.24 6.88e-03 GO:0016310 phosphorylation
1.24 7.03e-03 GO:0016265 death
1.22 7.27e-03 GO:0032268 regulation of cellular protein metabolic process
1.29 7.90e-03 GO:0000902 cell morphogenesis
1.34 8.11e-03 GO:0007409 axonogenesis
1.28 8.41e-03 GO:0032989 cellular component morphogenesis
1.24 8.43e-03 GO:0008219 cell death
1.26 8.69e-03 GO:0051049 regulation of transport
1.27 9.46e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.35 1.17e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.31 1.18e-02 GO:0048858 cell projection morphogenesis
1.32 1.34e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.25 1.43e-02 GO:0012501 programmed cell death
1.30 1.53e-02 GO:0032990 cell part morphogenesis
1.14 1.54e-02 GO:0042221 response to chemical stimulus
1.30 1.57e-02 GO:0001775 cell activation
1.23 1.81e-02 GO:0042592 homeostatic process
1.36 1.96e-02 GO:0007389 pattern specification process
1.30 2.11e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.13 2.14e-02 GO:0044267 cellular protein metabolic process
1.12 2.72e-02 GO:0071842 cellular component organization at cellular level
1.44 2.82e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.11 2.96e-02 GO:0019538 protein metabolic process
1.27 3.00e-02 GO:0009887 organ morphogenesis
1.36 3.04e-02 GO:0045597 positive regulation of cell differentiation
1.24 3.34e-02 GO:0006915 apoptosis
1.36 4.19e-02 GO:0007411 axon guidance
1.42 4.35e-02 GO:0030168 platelet activation
1.57 4.49e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.30 4.54e-02 GO:0008283 cell proliferation
1.12 4.70e-02 GO:0071841 cellular component organization or biogenesis at cellular level

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 2.43e-13 GO:0005737 cytoplasm
1.07 3.20e-13 GO:0044424 intracellular part
1.06 9.79e-12 GO:0005622 intracellular
1.11 5.09e-08 GO:0005634 nucleus
1.07 1.62e-07 GO:0043227 membrane-bounded organelle
1.07 2.98e-07 GO:0043231 intracellular membrane-bounded organelle
1.18 1.11e-06 GO:0005829 cytosol
1.03 1.12e-06 GO:0005623 cell
1.03 1.37e-06 GO:0044464 cell part
1.18 1.62e-06 GO:0044459 plasma membrane part
1.06 1.79e-06 GO:0043226 organelle
1.06 2.99e-06 GO:0043229 intracellular organelle
1.19 3.47e-06 GO:0031981 nuclear lumen
1.16 5.97e-05 GO:0044428 nuclear part
1.29 4.18e-04 GO:0030054 cell junction
1.19 6.27e-04 GO:0005654 nucleoplasm
1.14 1.10e-03 GO:0043233 organelle lumen
1.48 1.17e-03 GO:0030135 coated vesicle
1.52 2.20e-03 GO:0030136 clathrin-coated vesicle
1.23 3.00e-03 GO:0031982 vesicle
1.13 3.11e-03 GO:0031974 membrane-enclosed lumen
1.73 3.19e-03 GO:0000790 nuclear chromatin
1.13 3.44e-03 GO:0070013 intracellular organelle lumen
1.23 4.27e-03 GO:0031410 cytoplasmic vesicle
1.70 4.63e-03 GO:0030665 clathrin coated vesicle membrane
1.42 4.92e-03 GO:0016323 basolateral plasma membrane
1.07 5.27e-03 GO:0044446 intracellular organelle part
1.23 5.53e-03 GO:0031988 membrane-bounded vesicle
1.07 6.14e-03 GO:0044422 organelle part
1.23 8.25e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.31 8.88e-03 GO:0043005 neuron projection
1.40 1.15e-02 GO:0000785 chromatin
1.34 1.33e-02 GO:0044433 cytoplasmic vesicle part
1.30 1.37e-02 GO:0045202 synapse
1.57 1.40e-02 GO:0030662 coated vesicle membrane
1.06 4.16e-02 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 4.78e-33 GO:0005515 protein binding
1.07 3.74e-19 GO:0005488 binding
1.33 2.76e-10 GO:0030528 transcription regulator activity
1.40 6.66e-10 GO:0043565 sequence-specific DNA binding
1.30 3.58e-08 GO:0001071 nucleic acid binding transcription factor activity
1.30 3.58e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.62 9.31e-07 GO:0000975 regulatory region DNA binding
1.62 9.31e-07 GO:0001067 regulatory region nucleic acid binding
1.62 9.31e-07 GO:0044212 transcription regulatory region DNA binding
1.63 1.42e-06 GO:0010843 promoter binding
1.39 1.83e-05 GO:0019904 protein domain specific binding
1.46 2.09e-05 GO:0016563 transcription activator activity
1.63 1.75e-04 GO:0003714 transcription corepressor activity
1.37 8.22e-04 GO:0000988 protein binding transcription factor activity
1.37 8.22e-04 GO:0000989 transcription factor binding transcription factor activity
1.41 9.47e-04 GO:0008134 transcription factor binding
1.36 1.14e-03 GO:0003712 transcription cofactor activity
1.25 1.74e-02 GO:0004672 protein kinase activity
1.30 1.75e-02 GO:0004674 protein serine/threonine kinase activity