Motif ID: NFIX.p2

Z-value: 1.055


Transcription factors associated with NFIX.p2:

Gene SymbolEntrez IDGene Name
NFIX 4784 nuclear factor I/X (CCAAT-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFIXchr19_+_132059560.651.1e-04Click!


Activity profile for motif NFIX.p2.

activity profile for motif NFIX.p2


Sorted Z-values histogram for motif NFIX.p2

Sorted Z-values for motif NFIX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIX.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_47264669 3.753 NM_000779
NM_001099772
CYP4B1

cytochrome P450, family 4, subfamily B, polypeptide 1

chr19_+_41594367 3.602 NM_000766
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr19_-_3028901 3.577 NM_003260
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr19_-_41356193 3.495 NM_000762
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr10_-_105992062 3.058 NM_025145
WDR96
WD repeat domain 96
chr4_-_177116713 2.801 NM_144644
SPATA4
spermatogenesis associated 4
chr1_-_159869897 2.778 NM_012337
CCDC19
coiled-coil domain containing 19
chr14_-_100625931 2.556 NM_206918
DEGS2
delta(4)-desaturase, sphingolipid 2
chr6_-_109762373 2.462 NM_001111298
NM_173672
PPIL6

peptidylprolyl isomerase (cyclophilin)-like 6

chr5_+_122424840 2.456 NM_001136239
PRDM6
PR domain containing 6
chr12_+_50355278 2.418 NM_001651
AQP5
aquaporin 5
chrX_+_106449861 2.296 NM_001169154
NM_173494
CXorf41

chromosome X open reading frame 41

chr4_+_186317892 2.075 ANKRD37
ankyrin repeat domain 37
chr17_+_62075710 2.026 NM_001164257
NM_001191029
NM_001191030
NM_001191031
C17orf72



chromosome 17 open reading frame 72



chr1_+_210502639 1.942 NM_001170580
HHAT
hedgehog acyltransferase
chr22_-_41593466 1.926


chr21_+_33784751 1.860 NM_058187
C21orf63
chromosome 21 open reading frame 63
chrX_-_151999259 1.836 NM_004344
CETN2
centrin, EF-hand protein, 2
chr4_+_186317837 1.828 NM_181726
ANKRD37
ankyrin repeat domain 37
chr4_+_186317964 1.824 ANKRD37
ankyrin repeat domain 37
chr19_-_41388656 1.740 NM_000764
NM_030589
CYP2A7

cytochrome P450, family 2, subfamily A, polypeptide 7

chr16_-_28621279 1.635 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr15_-_56757239 1.621 NM_018365
MNS1
meiosis-specific nuclear structural 1
chr16_-_28608367 1.582 NM_001054
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr1_+_210502188 1.568 NM_001170587
NM_001170588
NM_018194
HHAT


hedgehog acyltransferase


chr17_-_19281494 1.535 NM_001243475
B9D1
B9 protein domain 1
chr3_+_130745693 1.446 NM_001146003
NM_024800
NM_145910
NEK11


NIMA (never in mitosis gene a)- related kinase 11


chr6_-_109761707 1.445 PPIL6
peptidylprolyl isomerase (cyclophilin)-like 6
chr11_-_75379651 1.404 MAP6
microtubule-associated protein 6
chr12_-_94853453 1.402 CCDC41
coiled-coil domain containing 41
chr6_+_109762043 1.356 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr4_-_75719686 1.347 NM_001729
BTC
betacellulin
chr3_-_46506342 1.331 NM_002343
LTF
lactotransferrin
chr6_+_109761887 1.322 NM_003080
SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr3_-_197676755 1.268 NM_001134435
IQCG
IQ motif containing G
chr17_+_1633754 1.228 WDR81
WD repeat domain 81
chr6_+_109762204 1.222 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr16_-_23724507 1.193 ERN2
endoplasmic reticulum to nucleus signaling 2
chr1_+_156890423 1.143 NM_144702
LRRC71
leucine rich repeat containing 71
chr10_+_102792161 1.143 SFXN3
sideroflexin 3
chr10_-_46168156 1.122 NM_001128324
NM_174890
ZFAND4

zinc finger, AN1-type domain 4

chr1_+_79086087 1.118 NM_006820
IFI44L
interferon-induced protein 44-like
chr19_+_859658 1.110 NM_001928
CFD
complement factor D (adipsin)
chr10_-_104211244 1.099 NM_024886
C10orf95
chromosome 10 open reading frame 95
chr11_-_111944757 1.075 NM_001082619
NM_138789
PIH1D2

PIH1 domain containing 2

chr11_+_17298278 1.065 NM_005013
NUCB2
nucleobindin 2
chr21_-_43373938 1.046 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr8_-_7212868 1.021 FAM66B
family with sequence similarity 66, member B
chr11_+_101918168 1.021 NM_001195005
NM_032930
C11orf70

chromosome 11 open reading frame 70

chr4_-_7044664 1.018 NM_153376
CCDC96
coiled-coil domain containing 96
chr16_+_58549382 0.994 NM_001160305
NM_024860
SETD6

SET domain containing 6

chr22_-_36019363 0.989 NM_203377
MB
myoglobin
chr5_+_141303463 0.969 KIAA0141
KIAA0141
chr3_-_12200339 0.965 TIMP4
TIMP metallopeptidase inhibitor 4
chr3_-_19975671 0.964 NM_144715
EFHB
EF-hand domain family, member B
chr15_+_82555101 0.947 NM_001008226
FAM154B
family with sequence similarity 154, member B
chr15_+_50474357 0.907 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr15_+_41062158 0.892 NM_001130448
C15orf62
chromosome 15 open reading frame 62
chr17_+_1627833 0.867 NM_001163811
WDR81
WD repeat domain 81
chr9_-_130667571 0.859 LOC100131355
ST6GALNAC6
uncharacterized LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr6_-_119470336 0.856 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr10_-_100174891 0.853 NM_032709
PYROXD2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr17_+_37844325 0.843 NM_001005862
ERBB2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chr12_-_94853696 0.823 NM_001042399
NM_016122
CCDC41

coiled-coil domain containing 41

chr15_+_45315301 0.815 NM_003104
SORD
sorbitol dehydrogenase
chr3_-_42003460 0.801 NM_017886
ULK4
unc-51-like kinase 4 (C. elegans)
chr17_+_40086875 0.801 NM_031421
TTC25
tetratricopeptide repeat domain 25
chr1_+_18807423 0.796 NM_152375
KLHDC7A
kelch domain containing 7A
chr14_-_100772774 0.795 NM_001039355
SLC25A29
solute carrier family 25, member 29
chr21_+_45993605 0.792 NM_198687
KRTAP10-4
keratin associated protein 10-4
chr11_+_86085777 0.767 NM_001156474
NM_021827
CCDC81

coiled-coil domain containing 81

chr19_-_7764283 0.766 NM_001207019
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr16_-_1660653 0.756 IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
chr14_+_65016613 0.754 NM_172365
PPP1R36
protein phosphatase 1, regulatory subunit 36
chr17_+_45908992 0.754 NM_033413
LRRC46
leucine rich repeat containing 46
chr17_+_1628032 0.752 NM_001163809
WDR81
WD repeat domain 81
chr12_+_26348268 0.749 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr1_+_43735664 0.743 NM_144626
TMEM125
transmembrane protein 125
chr16_+_58283819 0.737 NM_001142302
NM_014157
CCDC113

coiled-coil domain containing 113

chr1_+_32674694 0.730 NM_001099434
DCDC2B
doublecortin domain containing 2B
chr11_+_113185250 0.726 NM_017868
TTC12
tetratricopeptide repeat domain 12
chr21_+_42688660 0.725 NM_058186
NM_206964
FAM3B

family with sequence similarity 3, member B

chr5_-_38556682 0.718 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr11_+_27062508 0.705 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr9_-_130742803 0.705 NM_001035254
FAM102A
family with sequence similarity 102, member A
chr11_-_61735108 0.705 NM_002032
FTH1
ferritin, heavy polypeptide 1
chr3_-_12200850 0.699 NM_003256
TIMP4
TIMP metallopeptidase inhibitor 4
chr15_-_43559054 0.695 NM_004245
NM_201631
TGM5

transglutaminase 5

chr15_+_74466887 0.691 NM_201526
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr15_+_41952572 0.662 NM_001080541
NM_001164273
MGA

MAX gene associated

chr11_+_560868 0.655 NM_001143993
RASSF7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chrX_+_152240726 0.654 NM_001170944
NM_001242319
NM_032882
PNMA6C
PNMA6D
PNMA6A
paraneoplastic antigen like 6C
paraneoplastic antigen like 6D
paraneoplastic antigen like 6A
chr5_+_89854610 0.649 NM_032119
GPR98
G protein-coupled receptor 98
chr11_-_61735067 0.647 FTH1
CPSF7
ferritin, heavy polypeptide 1
cleavage and polyadenylation specific factor 7, 59kDa
chr8_+_145703439 0.645 PPP1R16A
protein phosphatase 1, regulatory subunit 16A
chr9_+_139927515 0.643 C9orf139
chromosome 9 open reading frame 139
chr1_-_152131703 0.640 NM_001122965
RPTN
repetin
chr14_-_65438794 0.633 NM_198686
RAB15
RAB15, member RAS onocogene family
chr3_+_113666544 0.629 NM_173570
ZDHHC23
zinc finger, DHHC-type containing 23
chr11_+_61159818 0.614 NM_001173990
NM_001173991
NM_016499
TMEM216


transmembrane protein 216


chr1_+_212738675 0.611 NM_001030287
ATF3
activating transcription factor 3
chr10_+_70587562 0.609 NM_001130162
STOX1
storkhead box 1
chr17_+_4981754 0.609 ZFP3
zinc finger protein 3 homolog (mouse)
chr3_-_122134881 0.602 NM_019069
WDR5B
WD repeat domain 5B
chr15_+_71184781 0.599 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chrX_+_10124984 0.594 NM_001830
CLCN4
chloride channel 4
chr19_+_859673 0.586 CFD
complement factor D (adipsin)
chr4_-_1166458 0.586 SPON2
spondin 2, extracellular matrix protein
chr4_-_25864430 0.584 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr17_+_4981721 0.573 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chr5_-_157002705 0.573


chr11_-_22647329 0.571 NM_022725
FANCF
Fanconi anemia, complementation group F
chr21_+_46020496 0.563 NM_198689
KRTAP10-7
keratin associated protein 10-7
chr19_+_45312294 0.560 NM_001013257
NM_005581
BCAM

basal cell adhesion molecule (Lutheran blood group)

chr8_+_101170231 0.558 NM_172218
SPAG1
sperm associated antigen 1
chr17_+_4613780 0.555 NM_004313
NM_199004
ARRB2

arrestin, beta 2

chr17_-_37844266 0.549 NM_033419
PGAP3
post-GPI attachment to proteins 3
chr5_+_10353802 0.548 NM_005885
MARCH6
membrane-associated ring finger (C3HC4) 6
chr11_-_49229878 0.546 FOLH1
folate hydrolase (prostate-specific membrane antigen) 1
chr17_+_4613931 0.544 ARRB2
arrestin, beta 2
chr1_+_46859918 0.541 NM_001441
FAAH
fatty acid amide hydrolase
chr9_+_104161118 0.539 NM_003452
NM_197977
ZNF189

zinc finger protein 189

chr15_-_26874236 0.539 NM_001191321
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr17_-_30186217 0.535 NM_018405
C17orf79
chromosome 17 open reading frame 79
chr9_-_116102533 0.535 NM_001012361
NM_145241
WDR31

WD repeat domain 31

chr5_-_111093030 0.535 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr4_-_38806410 0.533 NM_003263
TLR1
toll-like receptor 1
chr3_-_190580464 0.532 NM_001146686
GMNC
geminin coiled-coil domain containing
chr5_+_141303366 0.532 NM_001142603
NM_014773
KIAA0141

KIAA0141

chr2_+_132285469 0.531 NM_138770
CCDC74A
coiled-coil domain containing 74A
chr8_+_79578258 0.529 NM_016010
FAM164A
family with sequence similarity 164, member A
chr14_+_96152753 0.529 NM_004918
TCL1B
T-cell leukemia/lymphoma 1B
chr3_+_10290169 0.523 NM_014760
TATDN2
TatD DNase domain containing 2
chr14_+_105266878 0.521 NM_001137601
ZBTB42
zinc finger and BTB domain containing 42
chr2_+_149632772 0.515 NM_004522
KIF5C
kinesin family member 5C
chr19_-_59066477 0.514 NM_014453
CHMP2A
charged multivesicular body protein 2A
chr1_+_44457231 0.514 NM_152499
CCDC24
coiled-coil domain containing 24
chr15_-_72668184 0.514 HEXA
hexosaminidase A (alpha polypeptide)
chr6_-_106773529 0.510 ATG5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr3_+_10290204 0.507 TATDN2
TatD DNase domain containing 2
chr10_+_63422718 0.504 NM_173554
C10orf107
chromosome 10 open reading frame 107
chr11_+_61160098 0.504 TMEM216
transmembrane protein 216
chr1_+_212788359 0.499 NM_001206486
ATF3
activating transcription factor 3
chr16_+_23765947 0.495 NM_022097
CHP2
calcineurin B homologous protein 2
chr19_-_44860798 0.493 NM_001083335
NM_013380
ZFP112

zinc finger protein 112 homolog (mouse)

chr8_+_104383785 0.490 NM_138455
CTHRC1
collagen triple helix repeat containing 1
chr14_-_24911658 0.481 NM_020195
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr4_-_1166547 0.477 NM_012445
SPON2
spondin 2, extracellular matrix protein
chr8_-_102217868 0.477 NM_001042511
ZNF706
zinc finger protein 706
chr2_-_130902568 0.473 NM_207310
CCDC74B
coiled-coil domain containing 74B
chr1_-_149832696 0.472 NM_001034077
NM_003548
HIST2H4B
HIST2H4A
histone cluster 2, H4b
histone cluster 2, H4a
chr4_+_106816593 0.469 NM_001033047
NM_001184690
NM_001184691
NM_001184692
NM_001184693
NPNT




nephronectin




chr6_-_31745048 0.463 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr8_+_104383701 0.462 CTHRC1
collagen triple helix repeat containing 1
chr12_+_64237381 0.462


chr16_+_57406398 0.461 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr5_+_140787769 0.460 NM_018926
NM_032100
PCDHGB6

protocadherin gamma subfamily B, 6

chr1_-_1935275 0.459 NM_001080484
KIAA1751
KIAA1751
chr2_-_27851744 0.456 NM_001142683
NM_024584
CCDC121

coiled-coil domain containing 121

chrX_-_119379060 0.453 NKAPP1
NFKB activating protein pseudogene 1
chr12_+_108909049 0.452 NM_007076
FICD
FIC domain containing
chr11_+_10472223 0.448 NM_000480
AMPD3
adenosine monophosphate deaminase 3
chr15_+_56657615 0.444 NM_198524
TEX9
testis expressed 9
chr11_-_61734896 0.442 FTH1
ferritin, heavy polypeptide 1
chr14_+_59104736 0.439 NM_001079520
NM_016651
DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr6_-_106773607 0.439 NM_004849
ATG5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr7_-_77045706 0.438 NM_017439
PION
pigeon homolog (Drosophila)
chr1_-_23810721 0.437 NM_001143778
NM_017707
ASAP3

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

chr19_+_17516502 0.437 LOC100507535
uncharacterized LOC100507535
chr8_+_75262616 0.437 NM_018972
NM_001040875
GDAP1

ganglioside-induced differentiation-associated protein 1

chrX_-_136113832 0.436 NM_054021
GPR101
G protein-coupled receptor 101
chr16_-_52580805 0.434 NM_001080430
TOX3
TOX high mobility group box family member 3
chr9_-_136150629 0.430 NM_020469
ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr15_-_28567249 0.427 NM_004667
HERC2
hect domain and RLD 2
chr16_-_30905262 0.425 BCL7C
B-cell CLL/lymphoma 7C
chr16_+_2880172 0.425 NM_145252
ZG16B
zymogen granule protein 16 homolog B (rat)
chr4_+_146402704 0.425 NM_005900
SMAD1
SMAD family member 1
chr11_+_34642651 0.425 EHF
ets homologous factor
chr19_+_30156326 0.423 NM_024310
PLEKHF1
pleckstrin homology domain containing, family F (with FYVE domain) member 1
chr8_-_70745624 0.418 NM_001146008
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr17_+_6555037 0.417 NM_001105520
C17orf100
chromosome 17 open reading frame 100
chr5_-_111093251 0.414 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr10_-_123353330 0.414 NM_001144913
NM_001144914
FGFR2

fibroblast growth factor receptor 2

chr6_-_109330190 0.413 NM_001199934
SESN1
sestrin 1
chr17_-_26692264 0.413 NM_001080837
SEBOX
SEBOX homeobox
chr12_+_102091399 0.413 NM_020244
CHPT1
choline phosphotransferase 1
chr16_+_1384504 0.412 NM_003933
BAIAP3
BAI1-associated protein 3
chr19_-_59066353 0.412 NM_198426
CHMP2A
charged multivesicular body protein 2A
chr8_+_101170510 0.411 NM_003114
SPAG1
sperm associated antigen 1
chr19_-_59066303 0.409 CHMP2A
charged multivesicular body protein 2A
chr10_-_75173724 0.409 ANXA7
annexin A7
chr8_+_86089641 0.406


chr13_+_113622758 0.402 MCF2L
MCF.2 cell line derived transforming sequence-like
chr9_-_94124194 0.401 NM_001698
AUH
AU RNA binding protein/enoyl-CoA hydratase
chr9_+_132597651 0.400 NM_001110303
NM_006676
USP20

ubiquitin specific peptidase 20

chr21_-_43735705 0.397 NM_003226
TFF3
trefoil factor 3 (intestinal)
chr19_-_58090254 0.394 ZNF416
zinc finger protein 416
chr19_+_5914192 0.393 NM_004058
NM_080590
CAPS

calcyphosine

chr20_-_48530275 0.392 NM_001135773
SPATA2
spermatogenesis associated 2
chr10_-_99094427 0.391 NM_012083
FRAT2
frequently rearranged in advanced T-cell lymphomas 2

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 1.37e-04 GO:0043227 membrane-bounded organelle
1.14 2.06e-04 GO:0043231 intracellular membrane-bounded organelle
1.12 2.81e-04 GO:0043226 organelle
1.12 4.87e-04 GO:0043229 intracellular organelle
1.09 1.09e-03 GO:0044424 intracellular part
1.09 2.29e-03 GO:0005622 intracellular
1.12 8.04e-03 GO:0005737 cytoplasm
1.29 4.30e-02 GO:0031090 organelle membrane

Nothing significant found in function category.