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Motif ID: NKX3-1.p2

Z-value: 0.894

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_192127591	4.874	NM_130782	RGS18	regulator of G-protein signaling 18
chr5_+_147691988	3.449	NM_032566	SPINK7	serine peptidase inhibitor, Kazal type 7 (putative)
chr17_-_38859976	2.754	NM_019016	KRT24	keratin 24
chr3_-_149086884	2.130		TM4SF1	transmembrane 4 L six family member 1
chr20_+_30697291	1.903	NM_014742	TM9SF4	transmembrane 9 superfamily protein member 4
chr10_+_118187381	1.798	NM_001011709	PNLIPRP3	pancreatic lipase-related protein 3
chr6_+_134758840	1.792		LOC154092	uncharacterized LOC154092
chr12_+_85430098	1.712	NM_001079910	LRRIQ1	leucine-rich repeats and IQ motif containing 1
chr1_-_153363544	1.712	NM_002964	S100A8	S100 calcium binding protein A8
chr2_+_228356287	1.712		AGFG1	ArfGAP with FG repeats 1
chr1_+_84630575	1.711	NM_001242860 NM_001242861	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr5_+_92918924	1.675	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr16_+_55600583	1.664	NM_032330	CAPNS2	calpain, small subunit 2
chr7_-_41742666	1.599	NM_002192	INHBA	inhibin, beta A
chrX_-_107682600	1.440	NM_001847	COL4A6	collagen, type IV, alpha 6
chr7_+_80275967	1.411		CD36	CD36 molecule (thrombospondin receptor)
chr3_-_169487602	1.408	NM_032487	ARPM1	actin related protein M1
chr1_+_152974222	1.391	NM_001097589 NM_005416	SPRR3	small proline-rich protein 3
chr4_-_69111333	1.340	NM_182502	TMPRSS11B	transmembrane protease, serine 11B
chr4_-_103245468	1.316	NM_001135148	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr4_-_47983430	1.284	NM_001142564	CNGA1	cyclic nucleotide gated channel alpha 1
chr1_+_74701070	1.284	NM_015978	TNNI3K	TNNI3 interacting kinase
chr17_-_7493389	1.273	NM_006942	SOX15	SRY (sex determining region Y)-box 15
chr10_-_7682741	1.215		ITIH5	inter-alpha-trypsin inhibitor heavy chain family, member 5
chr1_+_150480486	1.165	NM_001202858 NM_004425 NM_022664	ECM1	extracellular matrix protein 1
chr17_+_9729380	1.129	NM_004246	GLP2R	glucagon-like peptide 2 receptor
chr10_+_102121371	1.045		SCD	stearoyl-CoA desaturase (delta-9-desaturase)
chr9_+_90112754	1.004	NM_004938	DAPK1	death-associated protein kinase 1
chr19_+_49078992	0.978	NM_004605	SULT2B1	sulfotransferase family, cytosolic, 2B, member 1
chr17_-_64225496	0.950	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr4_-_39033981	0.925	NM_024943	TMEM156	transmembrane protein 156
chr20_+_30697512	0.878		TM9SF4	transmembrane 9 superfamily protein member 4
chr4_+_69313166	0.872	NM_014058	TMPRSS11E	transmembrane protease, serine 11E
chr1_+_115572414	0.846	NM_000549	TSHB	thyroid stimulating hormone, beta
chr9_+_90112419	0.843		DAPK1	death-associated protein kinase 1
chr16_+_11439311	0.840		RMI2	RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr17_+_74463629	0.833	NM_001088	AANAT	aralkylamine N-acetyltransferase
chr8_-_15095791	0.832	NM_139167	SGCZ	sarcoglycan, zeta
chrX_+_107288199	0.823	NM_001170553 NM_182607	VSIG1	V-set and immunoglobulin domain containing 1
chr11_-_78052925	0.802	NM_012296	GAB2	GRB2-associated binding protein 2
chr7_+_80231503	0.790	NM_001001547	CD36	CD36 molecule (thrombospondin receptor)
chr2_+_102953716	0.788	NM_003856	IL1RL1	interleukin 1 receptor-like 1
chr1_-_149908098	0.778	NM_181873	MTMR11	myotubularin related protein 11
chr6_+_27292539	0.778	NM_032030	FKSG83	FKSG83
chr6_-_111888520	0.772	NM_001164283	TRAF3IP2	TRAF3 interacting protein 2
chr17_+_61086897	0.769	NM_025185	TANC2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr16_+_55515468	0.769	NM_001127891	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr15_-_80263460	0.767	NM_001114735 NM_004049	BCL2A1	BCL2-related protein A1
chrX_+_115301957	0.764	NM_000686	AGTR2	angiotensin II receptor, type 2
chr5_-_39203061	0.761		FYB	FYN binding protein
chr10_+_90346509	0.748	NM_001010939	LIPJ	lipase, family member J
chr20_-_52687303	0.747	NM_003657	BCAS1	breast carcinoma amplified sequence 1
chr9_+_105757592	0.743	NM_001340	CYLC2	cylicin, basic protein of sperm head cytoskeleton 2
chr4_-_68749698	0.738	NM_004262	TMPRSS11D	transmembrane protease, serine 11D
chr9_+_96846710	0.737	NM_001253829 NM_152422	PTPDC1	protein tyrosine phosphatase domain containing 1
chr12_-_29937691	0.734	NM_175861	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr5_-_132161863	0.725	NM_133456	SHROOM1	shroom family member 1
chr19_-_42931500	0.718	NM_005357	LIPE	lipase, hormone-sensitive
chr3_-_50340979	0.717	NM_007312 NM_033159 NM_153282 NM_153283 NM_153285	HYAL1	hyaluronoglucosaminidase 1
chr3_-_119963141	0.716	NM_001168271 NM_153002	GPR156	G protein-coupled receptor 156
chr2_+_64681270	0.714	NM_014181	LGALSL	lectin, galactoside-binding-like
chr9_+_116207010	0.714	NM_144488	RGS3	regulator of G-protein signaling 3
chr18_-_64271215	0.707	NM_021153	CDH19	cadherin 19, type 2
chr15_+_59904090	0.707		GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr14_+_67831484	0.696		EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr1_-_93342706	0.691	NM_001252271	FAM69A	family with sequence similarity 69, member A
chr13_-_20110884	0.686	NM_001141968 NM_130785 NM_199254	TPTE2	transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr7_+_143013218	0.680	NM_000083	CLCN1	chloride channel 1, skeletal muscle
chr1_+_171154387	0.674	NM_001460	FMO2	flavin containing monooxygenase 2 (non-functional)
chrX_+_91090459	0.672	NM_001168360 NM_001168361 NM_001168362 NM_001168363	PCDH11X	protocadherin 11 X-linked
chr5_+_140782367	0.659	NM_018921 NM_032089	PCDHGA9	protocadherin gamma subfamily A, 9
chr18_+_33234532	0.657	NM_020474	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr7_+_86273219	0.651	NM_000840	GRM3	glutamate receptor, metabotropic 3
chr16_-_31439650	0.651	NM_005205	COX6A2	cytochrome c oxidase subunit VIa polypeptide 2
chr5_+_96212167	0.647		ERAP2	endoplasmic reticulum aminopeptidase 2
chr5_+_147443534	0.642	NM_001127698 NM_001127699 NM_006846	SPINK5	serine peptidase inhibitor, Kazal type 5
chr7_+_134576187	0.631		CALD1	caldesmon 1
chr3_-_194188967	0.620	NM_024524	ATP13A3	ATPase type 13A3
chr4_-_153303663	0.608	NM_001013415	FBXW7	F-box and WD repeat domain containing 7
chrX_+_99839789	0.606	NM_022144	TNMD	tenomodulin
chr9_-_21305311	0.595	NM_002169	IFNA5	interferon, alpha 5
chr12_-_52779362	0.594	NM_033045	KRT84	keratin 84
chr1_+_84874033	0.584	NM_058248	DNASE2B	deoxyribonuclease II beta
chr6_-_49604524	0.580	NM_000324	RHAG	Rh-associated glycoprotein
chr3_-_74570262	0.577	NM_020872	CNTN3	contactin 3 (plasmacytoma associated)
chr20_+_30102313	0.575		HM13	histocompatibility (minor) 13
chr4_+_88529680	0.573	NM_014208	DSPP	dentin sialophosphoprotein
chr5_+_126859157	0.572		PRRC1	proline-rich coiled-coil 1
chr17_-_16875388	0.572	NM_012452	TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B
chr15_+_59903980	0.569	NM_004751	GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr18_+_19353635	0.562		MIB1	mindbomb homolog 1 (Drosophila)
chrX_+_100354797	0.561	NM_006733	CENPI	centromere protein I
chr4_+_187148624	0.550	NM_000892	KLKB1	kallikrein B, plasma (Fletcher factor) 1
chr14_-_106610338	0.550		IGHV4-31 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant gamma 1 (G1m marker)
chr5_-_119740531	0.546
chr9_-_21202201	0.546	NM_021057	IFNA7	interferon, alpha 7
chr6_-_32160637	0.540		GPSM3	G-protein signaling modulator 3
chr5_+_147258273	0.540	NM_054023	SCGB3A2	secretoglobin, family 3A, member 2
chr12_-_10324675	0.538	NM_001172632 NM_001172633 NM_002543	OLR1	oxidized low density lipoprotein (lectin-like) receptor 1
chr15_-_89764809	0.537	NM_000326	RLBP1	retinaldehyde binding protein 1
chr4_-_177190258	0.533	NM_080874	ASB5	ankyrin repeat and SOCS box containing 5
chr2_+_234959345	0.527	NM_006944	SPP2	secreted phosphoprotein 2, 24kDa
chr13_+_32313678	0.522	NM_001166058 NM_130806	RXFP2	relaxin/insulin-like family peptide receptor 2
chr1_-_231560789	0.520	NM_022051	EGLN1	egl nine homolog 1 (C. elegans)
chr12_+_20724797	0.517	NM_001244683	PDE3A	phosphodiesterase 3A, cGMP-inhibited
chr2_+_210444364	0.514	NM_002374 NM_031845 NM_031847	MAP2	microtubule-associated protein 2
chr5_-_9630462	0.512	NM_019599	TAS2R1	taste receptor, type 2, member 1
chr1_+_152784446	0.507	NM_178349	LCE1B	late cornified envelope 1B
chr3_-_196911001	0.507	NM_001204387 NM_001204388	DLG1	discs, large homolog 1 (Drosophila)
chr4_-_159093523	0.504		FAM198B	family with sequence similarity 198, member B
chr20_+_30102237	0.504	NM_030789 NM_178580 NM_178581 NM_178582	HM13	histocompatibility (minor) 13
chr19_+_9296269	0.502	NM_175883	OR7D2	olfactory receptor, family 7, subfamily D, member 2
chr18_+_61420276	0.502	NM_001040147	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chrX_-_100548044	0.498	NM_024885	TAF7L	TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr1_+_84630374	0.493		PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr12_+_93096618	0.493	NM_001037671 NM_001178097	C12orf74	chromosome 12 open reading frame 74
chr14_+_94492747	0.493		OTUB2	OTU domain, ubiquitin aldehyde binding 2
chr14_-_101036130	0.487	NM_020836	BEGAIN	brain-enriched guanylate kinase-associated homolog (rat)
chr12_+_56915587	0.481	NM_002898	RBMS2	RNA binding motif, single stranded interacting protein 2
chr2_-_165551178	0.478		COBLL1	COBL-like 1
chr11_+_57529233	0.468	NM_001085458 NM_001085459 NM_001085460 NM_001085461 NM_001085462 NM_001085463 NM_001085464 NM_001085465 NM_001085466 NM_001085467 NM_001085468 NM_001085469 NM_001206883 NM_001206884 NM_001206885 NM_001206886 NM_001206887 NM_001206888 NM_001206889 NM_001206890 NM_001206891 NM_001331	CTNND1	catenin (cadherin-associated protein), delta 1
chr22_+_40322609	0.467		GRAP2	GRB2-related adaptor protein 2
chr6_-_48078909	0.467		C6orf138	chromosome 6 open reading frame 138
chr11_+_55594694	0.464	NM_001004739	OR5L2	olfactory receptor, family 5, subfamily L, member 2
chr15_+_67841341	0.458	NM_001206804	MAP2K5	mitogen-activated protein kinase kinase 5
chr4_+_1902352	0.455	NM_133334	WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr11_+_55578842	0.453	NM_001004738	OR5L1	olfactory receptor, family 5, subfamily L, member 1
chr2_-_100046262	0.447		REV1	REV1 homolog (S. cerevisiae)
chrX_-_33229428	0.445	NM_004006	DMD	dystrophin
chr9_+_21409132	0.445	NM_002170	IFNA8	interferon, alpha 8
chr18_+_61554938	0.444	NM_001143818 NM_002575	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr12_-_56679729	0.443		CS	citrate synthase
chrX_+_107683015	0.443	NM_000495 NM_033380	COL4A5	collagen, type IV, alpha 5
chr12_-_10588543	0.441	NM_002260	KLRC2 KLRC3	killer cell lectin-like receptor subfamily C, member 2 killer cell lectin-like receptor subfamily C, member 3
chr7_+_134576150	0.435	NM_033139 NM_033140	CALD1	caldesmon 1
chr2_-_27718059	0.434		FNDC4	fibronectin type III domain containing 4
chr6_+_64286348	0.433		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr2_+_207406815	0.432		ADAM23	ADAM metallopeptidase domain 23
chr2_+_74057969	0.432		STAMBP	STAM binding protein
chr10_+_101088794	0.430	NM_020348	CNNM1	cyclin M1
chr7_+_115863004	0.426	NM_152829	TES	testis derived transcript (3 LIM domains)
chr4_+_169013687	0.424	NM_007193	ANXA10	annexin A10
chr8_-_17743062	0.423		FGL1	fibrinogen-like 1
chr11_+_124120422	0.421	NM_001002905	OR8G1	olfactory receptor, family 8, subfamily G, member 1
chrX_-_32430370	0.421	NM_004011 NM_004012	DMD	dystrophin
chr2_+_210444154	0.419		MAP2	microtubule-associated protein 2
chr10_-_98031154	0.416	NM_001114094 NM_013314	BLNK	B-cell linker
chr10_-_69752385	0.415		HERC4	hect domain and RLD 4
chr10_-_50342052	0.412	NM_001164484	FAM170B	family with sequence similarity 170, member B
chr12_-_68647225	0.406	NM_020525	IL22	interleukin 22
chrX_+_114827818	0.404	NM_001136025 NM_001172335	PLS3	plastin 3
chr1_-_51887740	0.402	NM_001159969	EPS15	epidermal growth factor receptor pathway substrate 15
chr9_-_104198045	0.401	NM_000035	ALDOB	aldolase B, fructose-bisphosphate
chr14_-_25078818	0.399	NM_033423	GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)
chr15_-_34331185	0.399	NM_020371	AVEN	apoptosis, caspase activation inhibitor
chr7_-_36764000	0.392	NM_001177506 NM_001177507 NM_001637	AOAH	acyloxyacyl hydrolase (neutrophil)
chr6_+_30130982	0.390	NM_033229	TRIM15	tripartite motif containing 15
chr6_-_76782204	0.385	NM_001563	IMPG1	interphotoreceptor matrix proteoglycan 1
chr19_-_39264144	0.384	NM_002307	LGALS7 LGALS7B	lectin, galactoside-binding, soluble, 7 lectin, galactoside-binding, soluble, 7B
chr2_-_27718098	0.383	NM_022823	FNDC4	fibronectin type III domain containing 4
chr10_+_5488521	0.380	NM_005863	NET1	neuroepithelial cell transforming 1
chr12_-_50595303	0.377	NM_001243775	LIMA1	LIM domain and actin binding 1
chr1_-_152086555	0.376	NM_007113	TCHH	trichohyalin
chrX_+_91089658	0.374	NM_014522 NM_032968 NM_032969	PCDH11X	protocadherin 11 X-linked
chr3_+_186915273	0.372	NM_153708	RTP1	receptor (chemosensory) transporter protein 1
chr12_+_47610244	0.370		FAM113B	family with sequence similarity 113, member B
chr17_+_3377346	0.366	NM_001128085	ASPA	aspartoacylase
chr3_+_85775631	0.361	NM_153184	CADM2	cell adhesion molecule 2
chr1_-_103496768	0.361		COL11A1	collagen, type XI, alpha 1
chr20_+_62795826	0.360	NM_004535	MYT1	myelin transcription factor 1
chr8_-_86253863	0.359	NM_001164830	CA1	carbonic anhydrase I
chr7_-_93519990	0.358	NM_006528	TFPI2	tissue factor pathway inhibitor 2
chr7_+_44240606	0.357		YKT6	YKT6 v-SNARE homolog (S. cerevisiae)
chr17_-_47925378	0.357	NM_001077503 NM_001077504 NM_001077505 NM_001077506 NM_170685	TAC4	tachykinin 4 (hemokinin)
chr19_-_14889347	0.353	NM_013447 NM_152916 NM_152917 NM_152918 NM_152919 NM_152920 NM_152921	EMR2	egf-like module containing, mucin-like, hormone receptor-like 2
chr19_-_51920841	0.349	NM_001171156 NM_001171157 NM_001171158 NM_001171159 NM_001171160 NM_001171161 NM_033130	SIGLEC10	sialic acid binding Ig-like lectin 10
chr18_-_22930826	0.349
chr2_-_10942642	0.343		PDIA6	protein disulfide isomerase family A, member 6
chr15_+_25281105	0.341		SNRPN	small nuclear ribonucleoprotein polypeptide N
chr6_+_153071931	0.341	NM_003381 NM_194435	VIP	vasoactive intestinal peptide
chr3_-_172858959	0.339	NM_031955	SPATA16	spermatogenesis associated 16
chr1_+_84647342	0.338	NM_001242862	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr12_-_48963802	0.338	NM_002289	LALBA	lactalbumin, alpha-
chr11_-_5537815	0.338	NM_145053	UBQLNL	ubiquilin-like
chr4_+_74269971	0.336	NM_000477	ALB	albumin
chr2_+_70121074	0.336	NM_006857	SNRNP27	small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr9_-_27005649	0.334	NM_022901	LRRC19	leucine rich repeat containing 19
chr3_-_113897849	0.332	NM_000796 NM_033663	DRD3	dopamine receptor D3
chr7_+_72300044	0.332		SBDSP1	Shwachman-Bodian-Diamond syndrome pseudogene 1
chr9_-_15250113	0.331	NM_001168342	TTC39B	tetratricopeptide repeat domain 39B
chr21_-_31864274	0.330	NM_181609	KRTAP19-3	keratin associated protein 19-3
chr12_-_18243052	0.330	NM_024730	RERGL	RERG/RAS-like
chr6_+_36644236	0.330	NM_001220777 NM_078467	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr11_-_13517525	0.327	NM_000315	PTH	parathyroid hormone
chr21_-_36252872	0.323		RUNX1	runt-related transcription factor 1
chr7_+_91924291	0.322
chr4_-_57547845	0.320	NM_001145460 NM_032495 NM_139212	HOPX	HOP homeobox
chr11_-_62752370	0.320	NM_004790 NM_153276 NM_153277 NM_153278	SLC22A6	solute carrier family 22 (organic anion transporter), member 6
chr20_+_30102261	0.318		HM13	histocompatibility (minor) 13
chr7_+_44240638	0.318		YKT6	YKT6 v-SNARE homolog (S. cerevisiae)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.91	2.73e-04	GO:0006952	defense response
1.23	1.85e-03	GO:0050896	response to stimulus
2.82	4.94e-02	GO:0019935	cyclic-nucleotide-mediated signaling

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.61	2.77e-07	GO:0005576	extracellular region
1.92	2.37e-05	GO:0005615	extracellular space
1.78	3.92e-05	GO:0044421	extracellular region part
6.82	4.11e-02	GO:0000159	protein phosphatase type 2A complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
7.95	5.96e-03	GO:0008601	protein phosphatase type 2A regulator activity
12.78	6.38e-03	GO:0005132	interferon-alpha/beta receptor binding
7.67	3.27e-02	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity