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Motif ID: NR6A1.p2

Z-value: 0.379

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_-_6720585	1.070	NM_000064	C3	complement component 3
chr11_-_108464344	0.638	NM_015065	EXPH5	exophilin 5
chr21_+_42688660	0.610	NM_058186 NM_206964	FAM3B	family with sequence similarity 3, member B
chr11_+_36317724	0.533	NM_001160167	PRR5L	proline rich 5 like
chr11_+_111789658	0.512		C11orf52	chromosome 11 open reading frame 52
chr16_+_776957	0.483	NM_032304	HAGHL	hydroxyacylglutathione hydrolase-like
chr10_+_81107259	0.410		PPIF	peptidylprolyl isomerase F
chr16_+_1386197	0.383	NM_001199096	BAIAP3	BAI1-associated protein 3
chr3_+_133464883	0.366	NM_001063	TF	transferrin
chr12_+_109273856	0.349	NM_001917	DAO	D-amino-acid oxidase
chr11_+_111789600	0.344	NM_080659	C11orf52	chromosome 11 open reading frame 52
chr17_-_29624249	0.338	NM_002544	OMG	oligodendrocyte myelin glycoprotein
chr12_+_7169192	0.330
chr7_-_150038689	0.322	NM_002889	RARRES2	retinoic acid receptor responder (tazarotene induced) 2
chr19_+_41620336	0.319	NM_000774	CYP2F1	cytochrome P450, family 2, subfamily F, polypeptide 1
chr16_+_31366519	0.315		ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)
chr7_+_100199881	0.308	NM_002593	PCOLCE	procollagen C-endopeptidase enhancer
chr14_-_106967528	0.308		IGHA1 IGHA2 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr6_+_43028181	0.300	NM_201522	KLC4	kinesin light chain 4
chr19_+_10196972	0.285		C19orf66	chromosome 19 open reading frame 66
chr9_-_14313899	0.272		NFIB	nuclear factor I/B
chr9_-_14313509	0.267		NFIB	nuclear factor I/B
chr21_-_43916298	0.231	NM_080860	RSPH1	radial spoke head 1 homolog (Chlamydomonas)
chr3_+_133465204	0.229		TF	transferrin
chr6_+_84743250	0.228	NM_138409	MRAP2	melanocortin 2 receptor accessory protein 2
chr20_-_7921068	0.226	NM_017545	HAO1	hydroxyacid oxidase (glycolate oxidase) 1
chr10_-_71892514	0.217		AIFM2	apoptosis-inducing factor, mitochondrion-associated, 2
chr10_+_89419352	0.215	NM_001015880 NM_004670	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr10_+_81107242	0.206		PPIF	peptidylprolyl isomerase F
chr20_-_3149070	0.205	NM_014731	ProSAPiP1	ProSAPiP1 protein
chr9_-_14314036	0.196	NM_001190737 NM_005596	NFIB	nuclear factor I/B
chr9_-_130679210	0.178	NM_175039 NM_175040	ST6GALNAC4	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr2_-_162930500	0.176		DPP4	dipeptidyl-peptidase 4
chr3_-_148804122	0.174	NM_003071 NM_139048	HLTF	helicase-like transcription factor
chr11_-_5462782	0.169	NM_001005288	OR51I1	olfactory receptor, family 51, subfamily I, member 1
chr7_-_65447206	0.168		GUSB	glucuronidase, beta
chr3_+_133465098	0.162		TF	transferrin
chr7_-_65447233	0.156	NM_000181	GUSB	glucuronidase, beta
chrX_-_21776158	0.150	NM_014332	SMPX	small muscle protein, X-linked
chr1_-_159825136	0.149	NM_001134233	C1orf204	chromosome 1 open reading frame 204
chr11_+_65192284	0.147		NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr12_+_121147830	0.147	NM_001080533	UNC119B	unc-119 homolog B (C. elegans)
chr19_+_10197023	0.146		C19orf66	chromosome 19 open reading frame 66
chr1_-_6761839	0.144		DNAJC11	DnaJ (Hsp40) homolog, subfamily C, member 11
chr1_+_212738675	0.144	NM_001030287	ATF3	activating transcription factor 3
chr8_-_145690737	0.143	NM_032687 NM_001129888	CYHR1	cysteine/histidine-rich 1
chr19_-_7796977	0.141	NM_001244856 NM_198492	CLEC4G	C-type lectin domain family 4, member G
chr17_-_9929567	0.137	NM_001130831	GAS7	growth arrest-specific 7
chr3_-_139396773	0.134	NM_001200047 NM_178177	NMNAT3	nicotinamide nucleotide adenylyltransferase 3
chr11_+_35684342	0.134	NM_017583	TRIM44	tripartite motif containing 44
chr12_-_7261788	0.131	NM_016546	C1RL	complement component 1, r subcomponent-like
chr16_+_31366529	0.130		ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)
chr1_+_225997742	0.128	NM_001136018	EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)
chr10_+_123754141	0.124		TACC2	transforming, acidic coiled-coil containing protein 2
chr11_+_35684418	0.122		TRIM44	tripartite motif containing 44
chr14_-_106111114	0.119		IGHG2	immunoglobulin heavy constant gamma 2 (G2m marker)
chr1_+_225997804	0.118		EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)
chr20_+_18794369	0.111	NM_178483	C20orf79	chromosome 20 open reading frame 79
chr7_-_65447162	0.111		GUSB	glucuronidase, beta
chr5_+_43603312	0.109		NNT	nicotinamide nucleotide transhydrogenase
chr14_-_106471439	0.104		IGHA1 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr2_-_162930544	0.101		DPP4	dipeptidyl-peptidase 4
chr9_-_38069207	0.096	NM_003028	SHB	Src homology 2 domain containing adaptor protein B
chr17_+_12692779	0.095	NM_014859	ARHGAP44	Rho GTPase activating protein 44
chr10_-_71892596	0.093	NM_001198696 NM_032797	AIFM2	apoptosis-inducing factor, mitochondrion-associated, 2
chr17_+_74075262	0.092	NM_180990	ZACN	zinc activated ligand-gated ion channel
chr2_+_18059923	0.091	NM_002252	KCNS3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chrY_+_16635625	0.087	NM_014893	NLGN4Y	neuroligin 4, Y-linked
chr14_-_106539099	0.083		IGHA1 IGHG1 IGHG3	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr5_+_63802427	0.082	NM_001029875	RGS7BP	regulator of G-protein signaling 7 binding protein
chr10_-_63212924	0.079		TMEM26	transmembrane protein 26
chr10_-_105238996	0.079	NM_001129742	CALHM3	calcium homeostasis modulator 3
chr1_+_19923457	0.077	NM_001204088 NM_001204089 NM_001032363 NM_001204082 NM_001204083	C1orf151-NBL1 MINOS1	C1orf151-NBL1 readthrough mitochondrial inner membrane organizing system 1
chr11_+_65383631	0.077	NM_032223	PCNXL3	pecanex-like 3 (Drosophila)
chr1_+_36387788	0.075		EIF2C1	eukaryotic translation initiation factor 2C, 1
chr6_-_132910824	0.072	NM_003967	TAAR5	trace amine associated receptor 5
chr3_+_185046682	0.071		MAP3K13	mitogen-activated protein kinase kinase kinase 13
chr2_-_162930629	0.069		DPP4	dipeptidyl-peptidase 4
chr5_-_14871555	0.067	NM_054027	ANKH	ankylosis, progressive homolog (mouse)
chr11_-_62472901	0.067
chr14_-_106733392	0.067		IGHG1 IGHG3	immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr12_+_108956293	0.066	NM_014301 NM_213595	ISCU	iron-sulfur cluster scaffold homolog (E. coli)
chr14_-_106641585	0.065		IGHV4-31 IGHA1 IGHA2 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_+_17653412	0.064	NM_001136024	NHS	Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr15_-_41166336	0.062	NM_133639	RHOV	ras homolog gene family, member V
chr3_-_52312257	0.057		WDR82	WD repeat domain 82
chr11_+_30344645	0.053	NM_152316	C11orf46	chromosome 11 open reading frame 46
chr5_-_42175355	0.052
chr9_-_114247024	0.052	NM_001080398	KIAA0368	KIAA0368
chr1_-_20834516	0.052		MUL1	mitochondrial E3 ubiquitin protein ligase 1
chr1_-_20834609	0.048	NM_024544	MUL1	mitochondrial E3 ubiquitin protein ligase 1
chrX_+_54466840	0.046	NM_058163	TSR2	TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr2_+_191002485	0.046	NM_001042521	C2orf88	chromosome 2 open reading frame 88
chr11_-_796175	0.046	NM_024698	SLC25A22	solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr19_-_2717272	0.043		DIRAS1	DIRAS family, GTP-binding RAS-like 1
chr11_+_111957611	0.043		SDHD	succinate dehydrogenase complex, subunit D, integral membrane protein
chr9_-_14313943	0.042		NFIB	nuclear factor I/B
chr3_-_128294928	0.042	NM_007354	C3orf27	chromosome 3 open reading frame 27
chr6_+_117803779	0.040	NM_173674	DCBLD1	discoidin, CUB and LCCL domain containing 1
chr8_-_53626991	0.037	NM_001083617 NM_014781	RB1CC1	RB1-inducible coiled-coil 1
chr3_+_186383770	0.036	NM_000412	HRG	histidine-rich glycoprotein
chr21_+_33765411	0.036		C21orf119	chromosome 21 open reading frame 119
chr11_-_111957417	0.034	NM_012459	TIMM8B	translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr11_-_64764388	0.033	NM_138456	BATF2	basic leucine zipper transcription factor, ATF-like 2
chrX_-_8139307	0.033	NM_016378	VCX2	variable charge, X-linked 2
chr12_-_16760935	0.031	NM_001001395 NM_001243609	LMO3	LIM domain only 3 (rhombotin-like 2)
chr9_+_124043719	0.031		GSN	gelsolin
chr19_+_45394642	0.029		TOMM40	translocase of outer mitochondrial membrane 40 homolog (yeast)
chr16_-_420508	0.029	NM_006428	MRPL28	mitochondrial ribosomal protein L28
chr16_+_56995761	0.029	NM_000078	CETP	cholesteryl ester transfer protein, plasma
chr21_-_45682098	0.028	NM_013369 NM_175867	DNMT3L	DNA (cytosine-5-)-methyltransferase 3-like
chr11_+_66624501	0.027		LRFN4	leucine rich repeat and fibronectin type III domain containing 4
chr16_+_24857551	0.027	NM_052944	SLC5A11	solute carrier family 5 (sodium/glucose cotransporter), member 11
chr11_+_111957533	0.026	NM_003002	SDHD	succinate dehydrogenase complex, subunit D, integral membrane protein
chr1_+_9299902	0.026		H6PD	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr14_+_89029371	0.026		ZC3H14	zinc finger CCCH-type containing 14
chr17_-_45056588	0.026	NM_203400	RPRML	reprimo-like
chrX_-_104465349	0.025	NM_031274	TEX13A	testis expressed 13A
chr7_-_87936202	0.025	NM_001205315 NM_001205316 NM_024636	STEAP4	STEAP family member 4
chr12_-_58135853	0.025	NM_014770	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr1_-_935469	0.024	NM_001142467 NM_021170	HES4	hairy and enhancer of split 4 (Drosophila)
chr9_-_135230358	0.023	NM_015046	SETX	senataxin
chr18_+_33767420	0.022	NM_017947	MOCOS	molybdenum cofactor sulfurase
chr3_+_46411632	0.022	NM_000579 NM_001100168	CCR5	chemokine (C-C motif) receptor 5
chr22_+_32010152	0.022		SFI1	Sfi1 homolog, spindle assembly associated (yeast)
chr9_-_135230129	0.022		SETX	senataxin
chr1_+_219347123	0.022	NM_138794	LYPLAL1	lysophospholipase-like 1
chr5_+_175308843	0.019		CPLX2	complexin 2
chr12_+_54410893	0.019		HOXC5 HOXC6	homeobox C5 homeobox C6
chr9_-_114362100	0.019	NM_001146108 NM_001146109	PTGR1	prostaglandin reductase 1
chr19_-_7698569	0.018	NM_174895	PCP2	Purkinje cell protein 2
chr2_-_162929928	0.017		DPP4	dipeptidyl-peptidase 4
chr1_+_33231260	0.016		KIAA1522	KIAA1522
chr2_-_211090146	0.015	NM_001608	ACADL	acyl-CoA dehydrogenase, long chain
chr7_-_2883649	0.015	NM_007353	GNA12	guanine nucleotide binding protein (G protein) alpha 12
chr3_-_71180061	0.014	NM_001244815	FOXP1	forkhead box P1
chr10_+_51837885	0.014	NM_018232	FAM21B	family with sequence similarity 21, member B
chr16_+_30676098	0.014		FBRS	fibrosin
chr17_+_75446735	0.013		SEPT9	septin 9
chr1_+_219347195	0.013		LYPLAL1	lysophospholipase-like 1
chr6_+_42982221	0.012	NM_001242872	KLHDC3	kelch domain containing 3
chr1_+_40997232	0.012	NM_152373	ZNF684	zinc finger protein 684
chr9_+_35792405	0.012	NM_003995	NPR2	natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr7_+_63773185	0.011	NM_001170905	ZNF736	zinc finger protein 736
chr20_-_43024303	0.011
chr1_-_158656487	0.011	NM_003126	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr10_+_47894022	0.010	NM_018232	FAM21B	family with sequence similarity 21, member B
chr8_-_37457357	0.010		LOC157860	uncharacterized LOC157860
chr5_+_140749830	0.010	NM_018924 NM_032097	PCDHGB3	protocadherin gamma subfamily B, 3
chr5_-_60458228	0.010	NM_001048249	C5orf43	chromosome 5 open reading frame 43
chr7_+_56032065	0.008	NM_001202469 NM_001483	GBAS	glioblastoma amplified sequence
chr5_-_156536185	0.007	NM_032782	HAVCR2	hepatitis A virus cellular receptor 2
chr2_-_31361364	0.007
chr19_+_496453	0.007	NM_130760 NM_130762	MADCAM1	mucosal vascular addressin cell adhesion molecule 1
chr16_-_28222700	0.006		XPO6	exportin 6
chr5_-_41213513	0.006	NM_000065	C6	complement component 6
chr16_+_3451154	0.006	NM_001032292 NM_003450	ZNF174	zinc finger protein 174
chr8_-_145701139	0.005		FOXH1	forkhead box H1
chr12_-_110252600	0.005	NM_001177431 NM_001177428 NM_001177433 NM_147204	TRPV4	transient receptor potential cation channel, subfamily V, member 4
chr17_+_75446612	0.005	NM_001113496	SEPT9	septin 9
chr19_+_41699076	0.005	NM_030622	CYP2S1	cytochrome P450, family 2, subfamily S, polypeptide 1
chr6_-_26032287	0.004	NM_003537	HIST1H3B	histone cluster 1, H3b
chr2_-_200715895	0.003		FONG	uncharacterized LOC348751
chr1_+_76190042	0.003	NM_000016 NM_001127328	ACADM	acyl-CoA dehydrogenase, C-4 to C-12 straight chain
chrY_-_1460901	0.002	NM_001636	SLC25A6	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr1_-_147624436	0.002	NM_183372	NBPF11	neuroblastoma breakpoint family, member 11
chr9_-_29738	0.001	NM_182905	WASH1	WAS protein family homolog 1
chr3_-_157213138	0.001	NM_001167917	VEPH1	ventricular zone expressed PH domain homolog 1 (zebrafish)
chrX_+_8432870	0.000	NM_001001888	VCX3B VCX3A	variable charge, X-linked 3B variable charge, X-linked 3A
chr7_-_100240334	0.000		TFR2	transferrin receptor 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
128.92	3.53e-02	GO:0001970	positive regulation of activation of membrane attack complex
128.92	3.53e-02	GO:0019254	carnitine metabolic process, CoA-linked
128.92	3.53e-02	GO:0045917	positive regulation of complement activation
128.92	3.53e-02	GO:2000259	positive regulation of protein activation cascade

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.87	1.19e-02	GO:0005624	membrane fraction
2.78	1.76e-02	GO:0005626	insoluble fraction
6.45	4.70e-02	GO:0044455	mitochondrial membrane part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
19.34	9.32e-05	GO:0003823	antigen binding
4.80	1.77e-02	GO:0048037	cofactor binding