Motif ID: NRF1.p2

Z-value: 3.456


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NRF1chr7_+_1292515290.752.0e-06Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_260092 34.441 NM_001013672
C17orf97
chromosome 17 open reading frame 97
chr2_-_99758034 17.770 NM_182911
TSGA10
testis specific, 10
chr4_-_7044664 15.444 NM_153376
CCDC96
coiled-coil domain containing 96
chr3_+_49449753 14.975 TCTA
T-cell leukemia translocation altered gene
chr3_+_49449638 12.850 NM_022171
TCTA
T-cell leukemia translocation altered gene
chr5_+_10441973 12.525 NM_001201466
NM_031916
ROPN1L

rhophilin associated tail protein 1-like

chr9_+_124922189 11.327 NM_198469
MORN5
MORN repeat containing 5
chr17_-_6735007 10.919 NM_053285
TEKT1
tektin 1
chr16_+_80574853 10.453 NM_130897
DYNLRB2
dynein, light chain, roadblock-type 2
chr14_+_75536298 9.486 NM_001042430
NM_024643
FAM164C

family with sequence similarity 164, member C

chr20_-_35580109 7.715 SAMHD1
SAM domain and HD domain 1
chr20_-_35580175 7.291 SAMHD1
SAM domain and HD domain 1
chr20_-_35580045 7.272 SAMHD1
SAM domain and HD domain 1
chr1_+_231473681 7.132 NM_001010984
NM_032018
C1orf124

chromosome 1 open reading frame 124

chr20_-_35580186 6.714 NM_015474
SAMHD1
SAM domain and HD domain 1
chr22_+_24666749 6.553 NM_001145468
NM_015330
SPECC1L

sperm antigen with calponin homology and coiled-coil domains 1-like

chr4_-_177116713 6.160 NM_144644
SPATA4
spermatogenesis associated 4
chr16_+_84178864 6.153 NM_178452
DNAAF1
dynein, axonemal, assembly factor 1
chr19_+_36236460 6.127 NM_172341
PSENEN
presenilin enhancer 2 homolog (C. elegans)
chr2_-_207630009 5.976 NM_001039845
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr17_+_7487125 5.975 MPDU1
mannose-P-dolichol utilization defect 1
chr5_+_10442065 5.871 ROPN1L
rhophilin associated tail protein 1-like
chr1_+_111889194 5.718 NM_181643
C1orf88
chromosome 1 open reading frame 88
chr1_-_160232269 5.711 DCAF8
DDB1 and CUL4 associated factor 8
chr12_-_68726036 5.609 NM_001205028
NM_001205029
NM_017440
NM_020128
MDM1



Mdm1 nuclear protein homolog (mouse)



chr2_+_228736326 5.298 NM_178821
WDR69
WD repeat domain 69
chr13_+_35516390 5.230 NM_015678
NBEA
neurobeachin
chr3_-_50383009 5.203 NM_015896
ZMYND10
zinc finger, MYND-type containing 10
chr19_-_5622794 5.101 NM_014649
SAFB2
scaffold attachment factor B2
chr22_-_23484208 5.029 NM_014433
RTDR1
rhabdoid tumor deletion region gene 1
chr11_+_63706433 4.910 NM_024771
NAA40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr22_-_31741761 4.811 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr20_-_55841090 4.660 BMP7
bone morphogenetic protein 7
chr6_-_39197225 4.595 NM_003740
KCNK5
potassium channel, subfamily K, member 5
chr17_+_7486964 4.539 NM_004870
MPDU1
mannose-P-dolichol utilization defect 1
chr7_+_158649200 4.487 NM_018051
WDR60
WD repeat domain 60
chrX_-_153707595 4.481 NM_006014
LAGE3
L antigen family, member 3
chr22_-_39548448 4.460 NM_175709
CBX7
chromobox homolog 7
chr1_+_197871681 4.457 NM_001024594
C1orf53
chromosome 1 open reading frame 53
chr2_-_160143062 4.404 NM_152528
NM_001128213
NM_001128212
WDSUB1


WD repeat, sterile alpha motif and U-box domain containing 1


chr1_-_67390413 4.277 NM_024763
NM_207014
WDR78

WD repeat domain 78

chr6_+_109169587 4.233 NM_032131
ARMC2
armadillo repeat containing 2
chr22_-_31742217 4.222 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr6_+_88117689 4.187 NM_001031743
C6orf165
chromosome 6 open reading frame 165
chr3_-_122134881 4.150 NM_019069
WDR5B
WD repeat domain 5B
chr16_-_776366 3.960 NM_001031737
CCDC78
coiled-coil domain containing 78
chr9_-_140024159 3.924


chr9_+_134378324 3.906 POMT1
protein-O-mannosyltransferase 1
chr5_-_159739482 3.881 NM_024565
CCNJL
cyclin J-like
chr17_-_27278471 3.805 NM_001033561
NM_020889
PHF12

PHD finger protein 12

chr17_+_9479943 3.754 NM_001080556
NM_145054
WDR16

WD repeat domain 16

chr11_+_101918168 3.742 NM_001195005
NM_032930
C11orf70

chromosome 11 open reading frame 70

chr5_-_132073143 3.706 NM_007054
KIF3A
kinesin family member 3A
chr1_+_91966365 3.664 NM_001134419
NM_003503
CDC7

cell division cycle 7 homolog (S. cerevisiae)

chr9_+_34458810 3.607 NM_012144
DNAI1
dynein, axonemal, intermediate chain 1
chr12_+_110906203 3.568 NM_013300
C12orf24
chromosome 12 open reading frame 24
chr16_+_3019341 3.565 NM_152341
PAQR4
progestin and adipoQ receptor family member IV
chr1_+_91966653 3.554 NM_001134420
CDC7
cell division cycle 7 homolog (S. cerevisiae)
chr6_+_163149001 3.538 NM_001080379
PACRG
PARK2 co-regulated
chr21_+_34697197 3.529 NM_000629
IFNAR1
interferon (alpha, beta and omega) receptor 1
chr4_+_128802015 3.513 NM_001190799
NM_014264
PLK4

polo-like kinase 4

chr17_+_45908992 3.505 NM_033413
LRRC46
leucine rich repeat containing 46
chr18_-_71814948 3.440 NM_152676
NM_001142958
FBXO15

F-box protein 15

chr7_+_100027404 3.345 MEPCE
methylphosphate capping enzyme
chr16_+_3019466 3.344 PAQR4
progestin and adipoQ receptor family member IV
chr21_-_43430448 3.283 NM_001098402
NM_001098403
NM_020727
ZNF295


zinc finger protein 295


chr17_+_35849950 3.275 NM_007026
DUSP14
dual specificity phosphatase 14
chr22_-_42310670 3.264 NM_001207020
SHISA8
shisa homolog 8 (Xenopus laevis)
chr21_+_40752242 3.242 WRB
tryptophan rich basic protein
chr21_+_40752212 3.239 NM_004627
WRB
tryptophan rich basic protein
chr16_+_29827489 3.230 NM_024516
C16orf53
chromosome 16 open reading frame 53
chr17_+_35849997 3.228 DUSP14
dual specificity phosphatase 14
chr1_+_227127993 3.212 ADCK3
aarF domain containing kinase 3
chr7_+_100027253 3.156 NM_019606
MEPCE
methylphosphate capping enzyme
chr7_-_122526781 3.119 NM_001009571
NM_001167940
NM_017954
CADPS2


Ca++-dependent secretion activator 2


chr2_+_101179395 3.069 NM_024065
PDCL3
phosducin-like 3
chr5_-_137368778 3.040 NM_001101800
NM_001101801
NM_016603
FAM13B


family with sequence similarity 13, member B


chr6_+_135502521 3.016 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr5_-_137368682 2.994 FAM13B
family with sequence similarity 13, member B
chr16_+_50099880 2.988 NM_182922
HEATR3
HEAT repeat containing 3
chr14_+_74486049 2.976 NM_025057
C14orf45
chromosome 14 open reading frame 45
chr13_+_37393306 2.976 NM_000538
RFXAP
regulatory factor X-associated protein
chr2_-_28113211 2.906 NM_022128
RBKS
ribokinase
chr2_-_27712520 2.900 NM_015662
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr19_-_40023449 2.894 NM_152361
EID2B
EP300 interacting inhibitor of differentiation 2B
chr13_-_36705432 2.869 DCLK1
doublecortin-like kinase 1
chr22_-_31742329 2.861 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr17_-_27278324 2.836 PHF12
PHD finger protein 12
chr4_+_128802064 2.831 NM_001190801
PLK4
polo-like kinase 4
chr17_+_7155371 2.817 NM_203415
NM_015362
NM_203413
NM_203414
C17orf81



chromosome 17 open reading frame 81



chr17_-_47439326 2.805 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr12_+_124457568 2.803 NM_001204299
NM_001204298
NM_152437
ZNF664-FAM101A
ZNF664

protein FAM101A
zinc finger protein 664

chr19_-_50432952 2.794 NM_016553
NUP62
nucleoporin 62kDa
chr13_-_20356788 2.747 PSPC1
paraspeckle component 1
chr6_-_43478423 2.745 NM_001012974
LRRC73
leucine rich repeat containing 73
chr19_+_9434854 2.735 NM_001172650
NM_001202412
ZNF559-ZNF177
ZNF559
ZNF559-ZNF177 readthrough
zinc finger protein 559
chr13_-_20357125 2.731 NM_001042414
PSPC1
paraspeckle component 1
chr11_+_62104882 2.730 ASRGL1
asparaginase like 1
chr16_-_75590107 2.708 NM_001077416
NM_001077418
NM_001077419
TMEM231


transmembrane protein 231


chr22_-_51222017 2.699 NM_001003789
NM_001130919
NM_001130920
NM_001130921
NM_001130922
NM_001130923
NM_007081
RABL2B






RAB, member of RAS oncogene family-like 2B






chr21_-_40817658 2.644 LCA5L
Leber congenital amaurosis 5-like
chr21_+_42676176 2.634 FAM3B
family with sequence similarity 3, member B
chr12_-_112450914 2.628 NM_001193453
NM_001193531
NM_138341
LOC728543
TMEM116


uncharacterized LOC728543
transmembrane protein 116


chr2_-_73460326 2.619 NM_032319
PRADC1
protease-associated domain containing 1
chr19_+_2328679 2.598 SPPL2B
signal peptide peptidase-like 2B
chr9_-_124922049 2.591 NM_014222
NDUFA8
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
chr1_+_183605207 2.585 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr1_+_40839368 2.585 NM_022733
SMAP2
small ArfGAP2
chr11_+_62104773 2.580 NM_001083926
NM_025080
ASRGL1

asparaginase like 1

chr7_+_149571029 2.578 ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr19_+_50979788 2.564 C19orf63
chromosome 19 open reading frame 63
chr20_-_30539853 2.563 NM_030815
PDRG1
p53 and DNA-damage regulated 1
chr20_-_30539803 2.561 PDRG1
p53 and DNA-damage regulated 1
chr19_+_54041332 2.557 NM_001079906
NM_001253798
NM_001253799
ZNF331


zinc finger protein 331


chr1_-_160232214 2.547 DCAF8
DDB1 and CUL4 associated factor 8
chr9_-_139839072 2.543 FBXW5
F-box and WD repeat domain containing 5
chr4_+_186317837 2.543 NM_181726
ANKRD37
ankyrin repeat domain 37
chr2_-_237416091 2.535 NM_024726
IQCA1
IQ motif containing with AAA domain 1
chr15_+_76352270 2.530 NM_152335
C15orf27
chromosome 15 open reading frame 27
chr19_+_54057898 2.521 NM_001253801
ZNF331
zinc finger protein 331
chr21_+_40752268 2.517 WRB
tryptophan rich basic protein
chr6_+_135502445 2.513 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr3_+_3841079 2.512 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr6_+_135502477 2.497 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr1_-_24104743 2.481 LOC100506963
uncharacterized LOC100506963
chr16_+_29827707 2.452 C16orf53
chromosome 16 open reading frame 53
chr14_+_74111577 2.445 NM_001201366
NM_031427
DNAL1

dynein, axonemal, light chain 1

chr7_+_102105459 2.443 LRWD1
leucine-rich repeats and WD repeat domain containing 1
chr4_+_186317892 2.442 ANKRD37
ankyrin repeat domain 37
chr3_+_73046081 2.428 NM_174907
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr10_-_127511832 2.420 NM_000375
UROS
uroporphyrinogen III synthase
chr6_-_39082750 2.417 NM_018322
C6orf64
chromosome 6 open reading frame 64
chr17_-_47755340 2.379 NM_001007226
NM_001007227
NM_001007228
NM_001007229
NM_001007230
NM_003563
SPOP





speckle-type POZ protein





chr17_+_62075710 2.367 NM_001164257
NM_001191029
NM_001191030
NM_001191031
C17orf72



chromosome 17 open reading frame 72



chr10_+_127512090 2.363 NM_016567
NM_078468
NM_078469
BCCIP


BRCA2 and CDKN1A interacting protein


chr19_-_5622725 2.363 SAFB2
scaffold attachment factor B2
chr20_-_30539725 2.343 PDRG1
p53 and DNA-damage regulated 1
chr19_+_50979656 2.303 NM_175063
NM_206538
C19orf63

chromosome 19 open reading frame 63

chr2_-_33824294 2.302 NM_015475
FAM98A
family with sequence similarity 98, member A
chr1_+_3773844 2.293 NM_004402
DFFB
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
chr19_-_10305600 2.287 DNMT1
DNA (cytosine-5-)-methyltransferase 1
chr19_+_9434447 2.284 NM_001202406
NM_001202407
NM_001202408
NM_001202409
NM_001202410
NM_001202411
NM_032497
ZNF559






zinc finger protein 559






chr5_+_134181729 2.265 C5orf24
chromosome 5 open reading frame 24
chrY_-_21906628 2.234 NM_001146705
NM_001146706
NM_004653
KDM5D


lysine (K)-specific demethylase 5D


chr3_-_150320949 2.234 SERP1
stress-associated endoplasmic reticulum protein 1
chr10_-_25304865 2.223 NM_145010
ENKUR
enkurin, TRPC channel interacting protein
chr3_-_53079959 2.214 SFMBT1
Scm-like with four mbt domains 1
chr1_+_246887591 2.210 SCCPDH
saccharopine dehydrogenase (putative)
chr19_-_41870001 2.208 NM_030578
B9D2
B9 protein domain 2
chr6_+_52284948 2.189 NM_018100
EFHC1
EF-hand domain (C-terminal) containing 1
chr1_+_228871109 2.187 RHOU
ras homolog gene family, member U
chr17_-_19281494 2.182 NM_001243475
B9D1
B9 protein domain 1
chr19_-_10305645 2.173 NM_001130823
NM_001379
DNMT1

DNA (cytosine-5-)-methyltransferase 1

chr7_+_102105367 2.170 NM_152892
LRWD1
leucine-rich repeats and WD repeat domain containing 1
chr19_-_10305536 2.164 DNMT1
DNA (cytosine-5-)-methyltransferase 1
chr6_-_99963245 2.162 NM_001080481
USP45
ubiquitin specific peptidase 45
chr2_-_190649075 2.153 NM_001128150
NM_016467
ORMDL1

ORM1-like 1 (S. cerevisiae)

chr7_-_36429695 2.149 NM_001100425
KIAA0895
KIAA0895
chr3_+_73045939 2.127 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr1_-_109969058 2.124 NM_001199772
NM_002790
NM_001199773
NM_001199774
PSMA5



proteasome (prosome, macropain) subunit, alpha type, 5



chr3_+_195384918 2.104 SDHAP1
SDHAP2
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
chr6_-_153304590 2.103 NM_001142522
FBXO5
F-box protein 5
chr3_-_14988939 2.098 LOC100505641
uncharacterized LOC100505641
chr3_-_107809754 2.077 NM_001777
NM_198793
CD47

CD47 molecule

chr14_-_102771469 2.076 NM_014226
MOK
MOK protein kinase
chr17_+_49337892 2.075 NM_016001
UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr3_+_14444083 2.058 NM_001134367
NM_001134368
NM_003043
SLC6A6


solute carrier family 6 (neurotransmitter transporter, taurine), member 6


chr17_+_49337909 2.057 UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr4_+_186317964 2.045 ANKRD37
ankyrin repeat domain 37
chr3_+_51705221 2.041 NM_001129884
NM_001243727
NM_015926
NM_001243725
NM_001243726
TEX264




testis expressed 264




chr3_-_45883562 2.040 NM_020347
LZTFL1
leucine zipper transcription factor-like 1
chr19_-_12807394 2.038 NM_032301
FBXW9
F-box and WD repeat domain containing 9
chr8_+_28351694 2.033 NM_017412
NM_145866
FZD3

frizzled family receptor 3

chr3_-_66024508 2.023 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr17_+_49337882 2.018 UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr2_+_54558070 2.014 NM_001100396
C2orf73
chromosome 2 open reading frame 73
chr14_+_89029252 2.007 NM_001160103
NM_001160104
NM_024824
NM_207660
ZC3H14



zinc finger CCCH-type containing 14



chr19_-_19144326 2.004 NM_001017392
NM_014884
SUGP2

SURP and G patch domain containing 2

chr16_+_89939992 1.996 NM_014972
TCF25
transcription factor 25 (basic helix-loop-helix)
chr1_+_118148506 1.994 NM_017709
FAM46C
family with sequence similarity 46, member C
chr17_+_28256873 1.992 NM_001145053
EFCAB5
EF-hand calcium binding domain 5
chr2_+_190526124 1.979 NM_019048
ASNSD1
asparagine synthetase domain containing 1
chr1_-_16162341 1.976 FLJ37453
uncharacterized LOC729614
chr1_-_234614848 1.961 NM_005646
TARBP1
TAR (HIV-1) RNA binding protein 1
chr12_+_93771607 1.953 NM_019094
NM_199040
NUDT4

NUDT4P1
nudix (nucleoside diphosphate linked moiety X)-type motif 4

nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1
chr2_+_99757947 1.937 NM_144706
C2orf15
chromosome 2 open reading frame 15
chr7_-_6746541 1.936 NM_006956
NM_016265
ZNF12

zinc finger protein 12

chr2_+_8822112 1.933 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr2_+_239229140 1.931 NM_001139490
NM_015650
TRAF3IP1

TNF receptor-associated factor 3 interacting protein 1

chr1_-_169396654 1.931 NM_021179
C1orf114
chromosome 1 open reading frame 114
chr1_-_202858225 1.922 NM_002871
RABIF
RAB interacting factor
chr19_+_2328628 1.915 NM_001077238
NM_152988
SPPL2B

signal peptide peptidase-like 2B

chr19_-_19144262 1.915 SUGP2
SURP and G patch domain containing 2
chr10_-_27389319 1.902 NM_014915
ANKRD26
ankyrin repeat domain 26
chr14_+_89029690 1.883 NM_207661
ZC3H14
zinc finger CCCH-type containing 14
chr19_+_49956472 1.876 NM_001145396
NM_153329
ALDH16A1

aldehyde dehydrogenase 16 family, member A1

chr5_-_130970803 1.866 RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr19_+_49956492 1.866 ALDH16A1
aldehyde dehydrogenase 16 family, member A1
chrX_+_152240726 1.862 NM_001170944
NM_001242319
NM_032882
PNMA6C
PNMA6D
PNMA6A
paraneoplastic antigen like 6C
paraneoplastic antigen like 6D
paraneoplastic antigen like 6A
chr1_-_3773620 1.857 CEP104
centrosomal protein 104kDa

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.48 1.26e-29 GO:0044260 cellular macromolecule metabolic process
1.70 3.71e-25 GO:0090304 nucleic acid metabolic process
1.40 1.58e-23 GO:0043170 macromolecule metabolic process
1.57 1.01e-21 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32 2.16e-21 GO:0044237 cellular metabolic process
1.47 1.19e-17 GO:0034641 cellular nitrogen compound metabolic process
1.45 1.04e-16 GO:0006807 nitrogen compound metabolic process
1.25 5.42e-16 GO:0008152 metabolic process
1.64 1.02e-15 GO:0016070 RNA metabolic process
2.13 9.12e-15 GO:0051276 chromosome organization
1.26 4.45e-14 GO:0044238 primary metabolic process
1.58 1.28e-13 GO:0010467 gene expression
2.13 1.22e-12 GO:0016071 mRNA metabolic process
2.01 2.36e-12 GO:0006396 RNA processing
2.04 8.27e-12 GO:0006259 DNA metabolic process
2.12 1.38e-10 GO:0006325 chromatin organization
2.00 2.15e-09 GO:0006974 response to DNA damage stimulus
2.21 2.52e-09 GO:0016568 chromatin modification
1.52 6.76e-09 GO:0006996 organelle organization
1.74 1.18e-08 GO:0033554 cellular response to stress
2.12 1.45e-08 GO:0006397 mRNA processing
2.28 1.64e-08 GO:0008380 RNA splicing
2.17 4.30e-08 GO:0006281 DNA repair
2.53 6.94e-08 GO:0000375 RNA splicing, via transesterification reactions
2.51 2.39e-07 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.51 2.39e-07 GO:0000398 nuclear mRNA splicing, via spliceosome
1.34 6.30e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.36 6.99e-07 GO:0044267 cellular protein metabolic process
1.41 9.81e-07 GO:0043412 macromolecule modification
1.32 1.44e-05 GO:0071842 cellular component organization at cellular level
2.03 5.67e-05 GO:0006366 transcription from RNA polymerase II promoter
1.37 1.30e-04 GO:0006464 protein modification process
1.50 2.63e-04 GO:0007049 cell cycle
1.62 3.05e-04 GO:0022403 cell cycle phase
3.18 3.31e-04 GO:0006405 RNA export from nucleus
1.97 5.86e-04 GO:0032446 protein modification by small protein conjugation
1.88 6.21e-04 GO:0070647 protein modification by small protein conjugation or removal
3.26 6.63e-04 GO:0006406 mRNA export from nucleus
1.36 8.25e-04 GO:0034645 cellular macromolecule biosynthetic process
1.36 9.61e-04 GO:0009059 macromolecule biosynthetic process
2.99 1.18e-03 GO:0006302 double-strand break repair
1.50 1.75e-03 GO:0006351 transcription, DNA-dependent
1.25 1.77e-03 GO:0019538 protein metabolic process
2.77 2.24e-03 GO:0051168 nuclear export
1.92 3.16e-03 GO:0034660 ncRNA metabolic process
1.94 3.32e-03 GO:0016567 protein ubiquitination
2.55 5.64e-03 GO:0043414 macromolecule methylation
1.59 6.62e-03 GO:0000278 mitotic cell cycle
1.21 1.02e-02 GO:0071840 cellular component organization or biogenesis
2.83 1.06e-02 GO:0006200 ATP catabolic process
2.08 1.34e-02 GO:0016570 histone modification
1.08 1.41e-02 GO:0009987 cellular process
1.59 1.85e-02 GO:0044265 cellular macromolecule catabolic process
1.54 1.92e-02 GO:0009057 macromolecule catabolic process
2.04 2.12e-02 GO:0016569 covalent chromatin modification
3.09 3.42e-02 GO:0000723 telomere maintenance
1.26 3.49e-02 GO:0051252 regulation of RNA metabolic process
1.97 4.34e-02 GO:0034470 ncRNA processing
1.41 4.49e-02 GO:0032774 RNA biosynthetic process
3.03 4.68e-02 GO:0032200 telomere organization
2.13 4.93e-02 GO:0006310 DNA recombination
1.45 5.00e-02 GO:0022402 cell cycle process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.33 1.21e-48 GO:0043231 intracellular membrane-bounded organelle
1.33 1.22e-48 GO:0043227 membrane-bounded organelle
1.49 3.41e-46 GO:0005634 nucleus
1.27 1.91e-42 GO:0043229 intracellular organelle
1.27 3.22e-42 GO:0043226 organelle
1.19 2.94e-35 GO:0005622 intracellular
1.20 1.02e-34 GO:0044424 intracellular part
1.75 8.68e-30 GO:0044428 nuclear part
1.71 6.01e-28 GO:0070013 intracellular organelle lumen
1.78 8.86e-27 GO:0031981 nuclear lumen
1.67 2.57e-26 GO:0031974 membrane-enclosed lumen
1.67 5.16e-26 GO:0043233 organelle lumen
1.91 1.55e-24 GO:0005654 nucleoplasm
1.32 1.13e-19 GO:0044446 intracellular organelle part
1.31 1.44e-18 GO:0044422 organelle part
1.95 1.24e-13 GO:0044451 nucleoplasm part
1.97 1.19e-10 GO:0005694 chromosome
1.31 1.72e-09 GO:0032991 macromolecular complex
1.89 2.61e-07 GO:0044427 chromosomal part
1.71 3.71e-05 GO:0030529 ribonucleoprotein complex
1.42 4.79e-05 GO:0005739 mitochondrion
1.26 7.96e-05 GO:0043234 protein complex
2.01 2.21e-04 GO:0000785 chromatin
3.30 3.24e-04 GO:0034708 methyltransferase complex
3.30 3.24e-04 GO:0035097 histone methyltransferase complex
1.24 1.79e-03 GO:0043228 non-membrane-bounded organelle
1.24 1.79e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.95 2.27e-03 GO:0000228 nuclear chromosome
1.59 3.80e-03 GO:0005730 nucleolus
2.26 4.68e-03 GO:0016607 nuclear speck
1.10 6.08e-03 GO:0005737 cytoplasm
2.14 6.38e-03 GO:0000151 ubiquitin ligase complex
1.87 7.37e-03 GO:0016604 nuclear body
2.00 7.76e-03 GO:0044454 nuclear chromosome part
2.54 8.11e-03 GO:0031461 cullin-RING ubiquitin ligase complex
1.70 8.52e-03 GO:0005815 microtubule organizing center
2.09 1.88e-02 GO:0005681 spliceosomal complex
1.04 2.26e-02 GO:0044464 cell part
1.04 2.34e-02 GO:0005623 cell
1.44 3.45e-02 GO:0015630 microtubule cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.48 4.02e-21 GO:0003676 nucleic acid binding
1.47 4.61e-13 GO:0003677 DNA binding
1.20 2.95e-11 GO:0005515 protein binding
1.10 4.08e-09 GO:0005488 binding
1.37 7.03e-08 GO:0000166 nucleotide binding
1.61 2.07e-06 GO:0003723 RNA binding
2.72 1.93e-05 GO:0016779 nucleotidyltransferase activity
1.18 7.02e-05 GO:0003824 catalytic activity
1.32 1.23e-04 GO:0008270 zinc ion binding
1.35 8.21e-04 GO:0005524 ATP binding
1.34 1.71e-03 GO:0032559 adenyl ribonucleotide binding
1.30 1.73e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.34 1.74e-03 GO:0030554 adenyl nucleotide binding
1.26 3.58e-03 GO:0046914 transition metal ion binding
1.63 3.99e-03 GO:0016874 ligase activity
2.91 4.40e-03 GO:0008276 protein methyltransferase activity
1.29 4.44e-03 GO:0032553 ribonucleotide binding
1.29 4.44e-03 GO:0032555 purine ribonucleotide binding
1.28 4.89e-03 GO:0017076 purine nucleotide binding
1.97 8.18e-03 GO:0003682 chromatin binding
2.42 9.41e-03 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
1.75 1.11e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
3.27 1.27e-02 GO:0003899 DNA-directed RNA polymerase activity
3.27 1.27e-02 GO:0034062 RNA polymerase activity
2.01 1.31e-02 GO:0008168 methyltransferase activity
1.77 1.64e-02 GO:0016881 acid-amino acid ligase activity
1.82 1.88e-02 GO:0019787 small conjugating protein ligase activity
1.63 2.25e-02 GO:0003712 transcription cofactor activity
1.63 2.47e-02 GO:0000988 protein binding transcription factor activity
1.63 2.47e-02 GO:0000989 transcription factor binding transcription factor activity
1.95 2.65e-02 GO:0016741 transferase activity, transferring one-carbon groups
4.99 3.26e-02 GO:0031593 polyubiquitin binding
1.89 3.73e-02 GO:0043566 structure-specific DNA binding
1.64 3.87e-02 GO:0016887 ATPase activity