Motif ID: ONECUT1,2.p2

Z-value: 0.839


Transcription factors associated with ONECUT1,2.p2:

Gene SymbolEntrez IDGene Name
ONECUT1 3175 one cut homeobox 1
ONECUT2 9480 one cut homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ONECUT1chr15_-_53082087-0.356.1e-02Click!
ONECUT2chr18_+_55102777-0.067.7e-01Click!


Activity profile for motif ONECUT1,2.p2.

activity profile for motif ONECUT1,2.p2


Sorted Z-values histogram for motif ONECUT1,2.p2

Sorted Z-values for motif ONECUT1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ONECUT1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_149792276 3.012 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr5_-_149792370 2.944 NM_001025158
NM_001025159
NM_004355
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr11_+_60467046 2.783 NM_031457
MS4A8B
membrane-spanning 4-domains, subfamily A, member 8B
chr15_-_43513024 2.649 EPB42
erythrocyte membrane protein band 4.2
chr11_-_47736896 2.267 NM_024783
AGBL2
ATP/GTP binding protein-like 2
chr19_-_14992166 2.212 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr15_-_43513196 2.049 EPB42
erythrocyte membrane protein band 4.2
chr15_-_43513234 2.049 NM_000119
NM_001114134
EPB42

erythrocyte membrane protein band 4.2

chr11_+_6897855 1.987 NM_207186
OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr8_+_17396285 1.903 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr3_-_183273407 1.737 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr12_-_122107559 1.654 NM_173855
MORN3
MORN repeat containing 3
chr3_-_167098070 1.627 NM_001199202
NM_001199201
NM_024687
ZBBX


zinc finger, B-box domain containing


chr7_+_23286384 1.598 GPNMB
glycoprotein (transmembrane) nmb
chr3_+_108015392 1.526 HHLA2
HERV-H LTR-associating 2
chrX_+_119029799 1.496 NM_001008534
NM_001008535
NM_178813
AKAP14


A kinase (PRKA) anchor protein 14


chr3_-_167371701 1.472 WDR49
WD repeat domain 49
chr3_+_171561138 1.449 NM_001164436
TMEM212
transmembrane protein 212
chr21_-_43735705 1.405 NM_003226
TFF3
trefoil factor 3 (intestinal)
chr1_-_151345156 1.343 NM_003944
SELENBP1
selenium binding protein 1
chr6_+_33043702 1.336 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr4_-_100212085 1.332 NM_000667
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr15_-_55800431 1.286 NM_001033559
NM_001033560
NM_130810
DYX1C1


dyslexia susceptibility 1 candidate 1


chr7_+_23286386 1.274 GPNMB
glycoprotein (transmembrane) nmb
chr12_-_91398744 1.256 EPYC
epiphycan
chr11_+_63137260 1.230 NM_080866
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr3_+_238274 1.222 NM_001253387
NM_006614
CHL1

cell adhesion molecule with homology to L1CAM (close homolog of L1)

chr5_-_43412417 1.141 NM_148672
CCL28
chemokine (C-C motif) ligand 28
chr16_+_78062985 1.094 NM_001244755
CLEC3A
C-type lectin domain family 3, member A
chr6_-_46922533 1.069 NM_015234
GPR116
G protein-coupled receptor 116
chr2_-_135782246 1.062 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr1_-_217262946 1.045 NM_001243506
NM_206594
NM_206595
ESRRG


estrogen-related receptor gamma


chr3_-_12200850 1.033 NM_003256
TIMP4
TIMP metallopeptidase inhibitor 4
chr3_-_155394104 1.030 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chr4_-_100356290 1.029 NM_001166504
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr7_+_23286277 1.022 NM_001005340
NM_002510
GPNMB

glycoprotein (transmembrane) nmb

chr20_+_31823801 1.008 NM_001243193
NM_016583
NM_130852
BPIFA1


BPI fold containing family A, member 1


chr16_-_23724820 0.978 NM_033266
ERN2
endoplasmic reticulum to nucleus signaling 2
chr11_+_17332454 0.959


chr5_+_140186658 0.958 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr1_-_26633110 0.957 NM_001077262
NM_183008
UBXN11

UBX domain protein 11

chr2_-_217540722 0.932 IGFBP5
insulin-like growth factor binding protein 5
chr7_+_23286420 0.930 GPNMB
glycoprotein (transmembrane) nmb
chr10_+_7745229 0.926 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chrX_-_117119282 0.916 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr3_-_112693711 0.912 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr22_+_24105207 0.911 NM_182520
C22orf15
chromosome 22 open reading frame 15
chr4_-_69886112 0.900 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr10_+_7745354 0.884 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr4_+_186350543 0.866 NM_001114357
C4orf47
chromosome 4 open reading frame 47
chr10_-_116392099 0.862 ABLIM1
actin binding LIM protein 1
chr6_-_32920812 0.858 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr5_-_160279045 0.857 NM_025153
ATP10B
ATPase, class V, type 10B
chr19_-_9092017 0.841 NM_024690
MUC16
mucin 16, cell surface associated
chr19_+_14491920 0.833 NM_001025160
NM_001784
NM_078481
CD97


CD97 molecule


chr19_+_41594367 0.827 NM_000766
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr7_+_23286390 0.826 GPNMB
glycoprotein (transmembrane) nmb
chr18_-_47814691 0.798 NM_001101654
NM_014593
CXXC1

CXXC finger protein 1

chr6_+_32407618 0.795 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr12_+_41831484 0.780 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr5_+_140247767 0.774 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr5_+_180794268 0.761 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr1_-_622033 0.758 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr4_-_38806410 0.754 NM_003263
TLR1
toll-like receptor 1
chr5_-_137475076 0.749 NM_003551
NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr10_+_7745325 0.741 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr20_+_43990576 0.739 NM_001197129
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr6_+_16143281 0.732 MYLIP
myosin regulatory light chain interacting protein
chr1_-_104238785 0.720 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr3_-_170744767 0.717 NM_000340
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr7_+_150382783 0.717 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr7_-_112726143 0.707 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr12_-_15091441 0.707 NM_152321
ERP27
endoplasmic reticulum protein 27
chr1_-_223853400 0.696 NM_001143962
CAPN8
calpain 8
chr6_+_31895201 0.693 NM_000063
NM_001145903
C2

complement component 2

chr7_-_105319608 0.688 NM_138495
ATXN7L1
ataxin 7-like 1
chr7_+_23286401 0.676 GPNMB
glycoprotein (transmembrane) nmb
chr15_-_60919642 0.674 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr1_+_104292278 0.629 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr8_+_110099652 0.628 NM_003301
TRHR
thyrotropin-releasing hormone receptor
chr8_-_110620220 0.628 SYBU
syntabulin (syntaxin-interacting)
chr8_-_103137134 0.626 NM_001040630
NCALD
neurocalcin delta
chr5_-_110062365 0.619 NM_001039763
TMEM232
transmembrane protein 232
chr12_+_49297892 0.616 NM_033124
CCDC65
coiled-coil domain containing 65
chr1_+_104292439 0.615 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr1_-_104239071 0.614 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr1_+_104198140 0.612 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr22_+_25591072 0.592 KIAA1671
KIAA1671
chr18_+_61370193 0.591 NM_080475
SERPINB11
serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
chr1_-_223853359 0.583 CAPN8
calpain 8
chr1_+_212788359 0.581 NM_001206486
ATF3
activating transcription factor 3
chr3_-_148939784 0.581 NM_000096
CP
ceruloplasmin (ferroxidase)
chr9_-_14086901 0.569 NFIB
nuclear factor I/B
chr3_+_132318980 0.567 NM_178445
CCRL1
chemokine (C-C motif) receptor-like 1
chr1_+_367639 0.564 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr5_-_124080773 0.564 NM_020747
ZNF608
zinc finger protein 608
chr22_+_46449674 0.560


chr1_+_104198301 0.555 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr2_-_32490688 0.541 NM_001199139
NM_021209
NLRC4

NLR family, CARD domain containing 4

chr4_-_100356449 0.541 NM_000673
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_-_217263195 0.537 NM_001243505
ESRRG
estrogen-related receptor gamma
chr6_+_131958441 0.534 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr3_+_108541544 0.510 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr12_-_7818467 0.493 NM_001644
APOBEC1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr8_-_117023 0.490 NM_001005504
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr10_+_695887 0.488 C10orf108
chromosome 10 open reading frame 108
chr13_-_36429798 0.484 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr12_-_4488707 0.481 NM_020638
FGF23
fibroblast growth factor 23
chr19_+_9361605 0.479 NM_001079935
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr10_+_51549552 0.477 NM_002443
NM_138634
MSMB

microseminoprotein, beta-

chr11_+_86085777 0.471 NM_001156474
NM_021827
CCDC81

coiled-coil domain containing 81

chr5_+_156696351 0.464 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr4_+_36285643 0.454 NM_001170700
DTHD1
death domain containing 1
chr14_+_91580967 0.451 NM_001102367
C14orf159
chromosome 14 open reading frame 159
chr6_-_79675672 0.445 PHIP
pleckstrin homology domain interacting protein
chrX_-_15288172 0.440 NM_001031739
NM_001168530
NM_024087
ASB9


ankyrin repeat and SOCS box containing 9


chr7_+_90339146 0.433 CDK14
cyclin-dependent kinase 14
chr5_+_42548144 0.433 NM_001242402
GHR
growth hormone receptor
chr3_-_112564789 0.430 NM_001008784
NM_001199215
CD200R1L

CD200 receptor 1-like

chr16_+_69680959 0.427 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr9_-_138853146 0.426 NM_016172
UBAC1
UBA domain containing 1
chr18_-_45663667 0.422 NM_001039360
ZBTB7C
zinc finger and BTB domain containing 7C
chr8_+_76452202 0.418 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr9_-_138853007 0.414 UBAC1
UBA domain containing 1
chr8_-_7212868 0.404 FAM66B
family with sequence similarity 66, member B
chr20_+_57022460 0.401 VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr12_-_70083055 0.400 NM_152439
BEST3
bestrophin 3
chr4_+_175839508 0.390 NM_001130703
NM_001130704
NM_001130705
NM_014269
ADAM29



ADAM metallopeptidase domain 29



chr19_+_35940616 0.386 NM_005306
FFAR2
free fatty acid receptor 2
chr16_+_15031299 0.382 NM_006985
NPIP
nuclear pore complex interacting protein
chr6_+_52284948 0.381 NM_018100
EFHC1
EF-hand domain (C-terminal) containing 1
chr6_-_167275657 0.379 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr8_+_67039130 0.378 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr20_+_15177503 0.372 NM_001033087
MACROD2
MACRO domain containing 2
chr5_+_140165875 0.371 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr12_-_86230158 0.363 NM_005447
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr20_+_1306033 0.363 LOC100507495
uncharacterized LOC100507495
chr9_+_273025 0.361 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr1_+_40862471 0.353 NM_001198980
SMAP2
small ArfGAP2
chr3_-_15839674 0.348 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr9_-_99417586 0.341 NM_153698
C9orf21
chromosome 9 open reading frame 21
chr2_+_170366211 0.338 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chrX_-_15288588 0.336 NM_001168531
ASB9
ankyrin repeat and SOCS box containing 9
chr6_-_76203256 0.333 NM_015687
FILIP1
filamin A interacting protein 1
chr5_+_140552201 0.331 NM_018940
PCDHB7
protocadherin beta 7
chr10_+_47083533 0.330 NM_005972
PPYR1
pancreatic polypeptide receptor 1
chr16_-_90096308 0.329 NM_001214
C16orf3
chromosome 16 open reading frame 3
chr8_-_17658385 0.328 NM_001001924
NM_001001925
MTUS1

microtubule associated tumor suppressor 1

chr19_+_13134782 0.326 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr16_+_69958900 0.326 NM_199424
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr12_-_86229981 0.322 RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr11_-_62911692 0.315 NM_001136506
SLC22A24
solute carrier family 22, member 24
chr12_+_86268072 0.312 NM_006183
NTS
neurotensin
chr15_-_37391893 0.312 MEIS2
Meis homeobox 2
chr3_-_114478117 0.312 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr5_+_159614373 0.311 NM_001130958
FABP6
fatty acid binding protein 6, ileal
chr3_-_15798057 0.311 NM_001195099
ANKRD28
ankyrin repeat domain 28
chr1_-_217250230 0.309 NM_001243507
NM_001243509
ESRRG

estrogen-related receptor gamma

chr14_+_91580467 0.308 C14orf159
chromosome 14 open reading frame 159
chr4_-_170077807 0.308 SH3RF1
SH3 domain containing ring finger 1
chr5_-_68616299 0.306 NM_176816
CCDC125
coiled-coil domain containing 125
chr3_-_64211111 0.302 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr16_+_56225301 0.302 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr7_+_94292737 0.300 PEG10
paternally expressed 10
chr9_+_140135698 0.298 NM_006088
TUBB4B
tubulin, beta 4B class IVb
chr6_-_49712055 0.298 NM_001190986
NM_006061
CRISP3

cysteine-rich secretory protein 3

chr4_+_69681709 0.297 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr1_+_174843523 0.296 NM_001243763
RABGAP1L
RAB GTPase activating protein 1-like
chr6_-_79787784 0.296 PHIP
pleckstrin homology domain interacting protein
chr7_+_120590816 0.296 NM_019071
NM_198267
ING3

inhibitor of growth family, member 3

chr2_+_132480063 0.293 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr1_+_161123510 0.290 NM_016406
UFC1
ubiquitin-fold modifier conjugating enzyme 1
chr20_-_1974393 0.288 NM_001190900
PDYN
prodynorphin
chr17_-_5138049 0.288 NM_207103
SCIMP
SLP adaptor and CSK interacting membrane protein
chr16_-_11367451 0.283 NM_021247
PRM3
protamine 3
chr20_+_58571416 0.279 NM_021810
CDH26
cadherin 26
chr4_-_84035888 0.276 PLAC8
placenta-specific 8
chr16_+_21245015 0.275 NM_145865
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr1_+_244214552 0.270 NM_205768
ZNF238
zinc finger protein 238
chr11_-_102651321 0.269 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr2_+_135596185 0.266 NM_138326
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr7_+_94297448 0.266 PEG10
paternally expressed 10
chr10_-_21186530 0.265 NM_006393
NEBL
nebulette
chr16_+_67381252 0.263 NM_001161575
LRRC36
leucine rich repeat containing 36
chr18_-_52969714 0.263 NM_001243236
TCF4
transcription factor 4
chr17_+_3377346 0.261 NM_001128085
ASPA
aspartoacylase
chr3_-_93692898 0.259 NM_000313
PROS1
protein S (alpha)
chr7_+_94539209 0.257 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr9_-_123812535 0.256 NM_001735
C5
complement component 5
chr19_+_52848681 0.255 NM_173530
ZNF610
zinc finger protein 610
chr6_-_32634287 0.254 NM_001243961
NM_002123
HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

chr6_+_56954889 0.253 ZNF451
zinc finger protein 451
chr1_-_174992552 0.253 NM_022100
MRPS14
mitochondrial ribosomal protein S14
chr13_+_99058147 0.253


chr18_-_53303129 0.252 NM_001243226
TCF4
transcription factor 4
chr8_+_123794043 0.250 ZHX2
zinc fingers and homeoboxes 2
chr11_+_58710721 0.249 NM_001220496
NM_080661
GLYATL1

glycine-N-acyltransferase-like 1

chr1_+_46859918 0.246 NM_001441
FAAH
fatty acid amide hydrolase
chr7_-_6746541 0.246 NM_006956
NM_016265
ZNF12

zinc finger protein 12

chr2_-_188312872 0.245 NM_005795
CALCRL
calcitonin receptor-like

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
5.62 4.84e-02 GO:0042611 MHC protein complex

Nothing significant found in function category.