Motif ID: PATZ1.p2

Z-value: 1.355


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PATZ1chr22_-_31741761-0.374.4e-02Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_131183225 10.017 CERCAM
cerebral endothelial cell adhesion molecule
chr8_-_144650998 5.119 C8orf73
chromosome 8 open reading frame 73
chr6_-_4135701 5.098 NM_001166010
NM_006117
NM_206836
ECI2


enoyl-CoA delta isomerase 2


chr9_+_131183122 5.025 CERCAM
cerebral endothelial cell adhesion molecule
chr6_+_37137882 4.140 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr19_-_51487070 4.139 NM_139277
NM_001207053
NM_001243126
NM_005046
KLK7



kallikrein-related peptidase 7



chr2_-_216300770 3.654 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr19_-_51472003 3.550 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr8_+_86376130 3.525 NM_000067
CA2
carbonic anhydrase II
chr1_+_37940129 3.366 ZC3H12A
zinc finger CCCH-type containing 12A
chrX_+_43514157 3.295 MAOA
monoamine oxidase A
chr6_+_34205029 3.235 HMGA1
high mobility group AT-hook 1
chr19_+_54371150 3.181 MYADM
myeloid-associated differentiation marker
chr9_+_131182690 2.994 NM_016174
CERCAM
cerebral endothelial cell adhesion molecule
chr10_-_25241504 2.966 NM_020200
PRTFDC1
phosphoribosyl transferase domain containing 1
chr1_+_37940074 2.899 NM_025079
ZC3H12A
zinc finger CCCH-type containing 12A
chr19_-_55658310 2.882 TNNT1
troponin T type 1 (skeletal, slow)
chr20_+_34203746 2.851 NM_003116
SPAG4
sperm associated antigen 4
chr2_-_72374919 2.812 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr1_+_37940180 2.801 ZC3H12A
zinc finger CCCH-type containing 12A
chr17_-_76921076 2.762 TIMP2
TIMP metallopeptidase inhibitor 2
chr19_+_54371125 2.761 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr8_-_144650884 2.667 C8orf73
chromosome 8 open reading frame 73
chr19_+_54371170 2.433 MYADM
myeloid-associated differentiation marker
chr1_-_11714396 2.351 FBXO2
F-box protein 2
chr17_-_76921205 2.331 TIMP2
TIMP metallopeptidase inhibitor 2
chr19_-_51504799 2.271 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr1_-_11714738 2.191 NM_012168
FBXO2
F-box protein 2
chr19_-_19052032 2.172 NM_004838
HOMER3
homer homolog 3 (Drosophila)
chr21_-_44496423 2.171 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr1_-_17307107 2.139 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr19_-_19051899 2.108 HOMER3
homer homolog 3 (Drosophila)
chr17_-_43209681 2.059 NM_133373
PLCD3
phospholipase C, delta 3
chr16_-_90085786 2.059 NM_001042610
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr5_+_150632612 2.032 NM_000405
NM_001167607
GM2A

GM2 ganglioside activator

chr11_+_46403279 2.007 MDK
midkine (neurite growth-promoting factor 2)
chr1_-_11714471 2.004 FBXO2
F-box protein 2
chr19_-_54984341 1.988 NM_145057
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr10_-_75634219 1.942 NM_001204492
NM_001222
NM_172169
NM_172170
NM_172171
NM_172173
CAMK2G





calcium/calmodulin-dependent protein kinase II gamma





chr2_+_70142303 1.937 MXD1
MAX dimerization protein 1
chr6_+_34205369 1.894 HMGA1
high mobility group AT-hook 1
chr6_-_30655078 1.882 NM_001134870
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr6_-_30654978 1.847 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr1_-_20812271 1.815 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_-_1513187 1.737 NM_213604
ADAMTSL5
ADAMTS-like 5
chr1_-_204121144 1.735 NM_018208
ETNK2
ethanolamine kinase 2
chr19_+_35491225 1.724 NM_001136199
NM_020895
GRAMD1A

GRAM domain containing 1A

chr9_-_34397786 1.705 NM_032596
C9orf24
chromosome 9 open reading frame 24
chr12_-_125348266 1.695 SCARB1
scavenger receptor class B, member 1
chr1_-_204120909 1.691 ETNK2
ethanolamine kinase 2
chr15_+_80445177 1.684 NM_000137
FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr17_+_37896219 1.682 NM_001242443
GRB7
growth factor receptor-bound protein 7
chr19_+_8429010 1.680 NM_001039667
NM_139314
ANGPTL4

angiopoietin-like 4

chr19_+_54926721 1.670 TTYH1
tweety homolog 1 (Drosophila)
chr22_-_26986065 1.631 TPST2
tyrosylprotein sulfotransferase 2
chr9_+_139560243 1.631 EGFL7
EGF-like-domain, multiple 7
chr18_+_11981421 1.629 NM_014214
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr22_-_26986071 1.625 NM_003595
TPST2
tyrosylprotein sulfotransferase 2
chr12_+_57522247 1.618 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr14_+_94640648 1.608 NM_020958
NM_058237
PPP4R4

protein phosphatase 4, regulatory subunit 4

chr19_+_54372659 1.587 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr16_+_90015138 1.584 NM_001242816
NM_001242817
NM_001242818
NM_001242820
NM_001242821
NM_001242822
NM_017702
NM_207514
DEF8







differentially expressed in FDCP 8 homolog (mouse)







chr7_-_98741375 1.583 SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr17_-_76921453 1.582 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr19_+_54926604 1.575 NM_001005367
NM_001201461
NM_020659
TTYH1


tweety homolog 1 (Drosophila)


chr7_+_2671582 1.574 NM_025250
TTYH3
tweety homolog 3 (Drosophila)
chr2_-_216300444 1.560 FN1
fibronectin 1
chr1_+_182992694 1.553


chr11_+_46403302 1.539 NM_001012333
MDK
midkine (neurite growth-promoting factor 2)
chr18_+_11981552 1.532 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr9_+_139560193 1.503 NM_201446
EGFL7
EGF-like-domain, multiple 7
chr11_+_46403205 1.501 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr17_-_74497406 1.478 NM_024599
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr22_+_31477231 1.461 NM_006932
NM_134269
NM_134270
SMTN


smoothelin


chr6_+_34204928 1.459 HMGA1
high mobility group AT-hook 1
chr17_-_76356153 1.456 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr19_-_39227588 1.456 CAPN12
calpain 12
chr19_-_15343767 1.445 NM_001142886
EPHX3
epoxide hydrolase 3
chr7_+_73082320 1.442 VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr12_+_70759974 1.441 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr21_-_44495894 1.425 NM_000071
CBS
cystathionine-beta-synthase
chr7_+_2671630 1.408 TTYH3
tweety homolog 3 (Drosophila)
chr18_+_33877630 1.408 NM_025135
FHOD3
formin homology 2 domain containing 3
chr9_-_35115844 1.397 NM_025182
FAM214B
family with sequence similarity 214, member B
chr2_+_70142236 1.396 MXD1
MAX dimerization protein 1
chr14_+_24867926 1.394 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr19_+_45349560 1.391 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr7_-_149470294 1.389 NM_207336
ZNF467
zinc finger protein 467
chr7_-_102257199 1.388 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr9_+_34989637 1.344 NM_001135004
NM_012266
DNAJB5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr2_-_235405692 1.331 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr22_+_51113069 1.320 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chrX_+_135229536 1.315 NM_001159702
NM_001159703
NM_001449
FHL1


four and a half LIM domains 1


chr6_-_112194430 1.311 FYN
FYN oncogene related to SRC, FGR, YES
chr7_-_102257135 1.303 RASA4
RAS p21 protein activator 4
chr16_+_66638530 1.292 NM_181553
CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr16_+_90015827 1.286 NM_001242819
DEF8
differentially expressed in FDCP 8 homolog (mouse)
chr22_+_33197744 1.283 TIMP3
TIMP metallopeptidase inhibitor 3
chr17_-_48262900 1.279 COL1A1
collagen, type I, alpha 1
chr2_-_9143742 1.267 NM_138799
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr16_+_66638652 1.267 CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr12_-_125348422 1.260 NM_001082959
NM_005505
SCARB1

scavenger receptor class B, member 1

chr11_-_66725790 1.259 NM_000920
NM_001040716
PC

pyruvate carboxylase

chr22_+_33197678 1.256 TIMP3
TIMP metallopeptidase inhibitor 3
chr22_-_43583132 1.248 NM_015140
TTLL12
tubulin tyrosine ligase-like family, member 12
chr20_+_56884749 1.248 NM_020673
RAB22A
RAB22A, member RAS oncogene family
chr17_-_76124767 1.247 TMC6
transmembrane channel-like 6
chr3_-_53290099 1.242 NM_001064
NM_001135055
TKT

transketolase

chr19_-_19051112 1.238 NM_001145722
NM_001145721
HOMER3

homer homolog 3 (Drosophila)

chr9_+_34990266 1.236 NM_001135005
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr7_-_143059696 1.236 NM_001031690
FAM131B
family with sequence similarity 131, member B
chr1_-_168105902 1.230 GPR161
G protein-coupled receptor 161
chr12_-_54813002 1.226 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chrX_-_134232663 1.215 LINC00087
long intergenic non-protein coding RNA 87
chr13_+_43355685 1.213 NM_182508
C13orf30
chromosome 13 open reading frame 30
chr16_-_56459302 1.212 AMFR
autocrine motility factor receptor
chr5_-_171881355 1.210 SH3PXD2B
SH3 and PX domains 2B
chr12_-_125348346 1.210 SCARB1
scavenger receptor class B, member 1
chr16_+_29823408 1.204 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr4_+_99182520 1.171 NM_001100426
NM_001100427
NM_001100428
NM_001100429
NM_001100430
NM_021159
RAP1GDS1





RAP1, GTP-GDP dissociation stimulator 1





chr14_-_53417636 1.170 FERMT2
fermitin family member 2
chr19_-_51143091 1.170 NM_001160328
NM_001160329
SYT3

synaptotagmin III

chr19_+_1446268 1.169 APC2
adenomatosis polyposis coli 2
chr8_-_29207795 1.168 NM_001394
DUSP4
dual specificity phosphatase 4
chr1_+_182992329 1.160 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr2_+_24272627 1.159 FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr9_-_110251754 1.151 KLF4
Kruppel-like factor 4 (gut)
chr10_-_17659365 1.149 NM_014241
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr11_+_46402333 1.147 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr9_-_131872907 1.147 NM_000755
CRAT
carnitine O-acetyltransferase
chr7_+_73082157 1.139 NM_001077621
VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr16_+_29823557 1.139 PRRT2
proline-rich transmembrane protein 2
chr10_+_102756829 1.138 NM_032429
LZTS2
leucine zipper, putative tumor suppressor 2
chr21_-_38639593 1.133 DSCR3
Down syndrome critical region gene 3
chr10_+_28966419 1.125 NM_012342
BAMBI
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
chr9_-_34381497 1.119 NM_001252195
NM_147168
NM_147169
C9orf24


chromosome 9 open reading frame 24


chr22_-_43583058 1.107 TTLL12
tubulin tyrosine ligase-like family, member 12
chr14_-_53417808 1.102 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr7_-_143059144 1.099 NM_014690
FAM131B
family with sequence similarity 131, member B
chr20_+_56725982 1.097 NM_178456
C20orf85
chromosome 20 open reading frame 85
chr19_-_11308184 1.091 NM_001136191
KANK2
KN motif and ankyrin repeat domains 2
chr16_-_87903028 1.086 NM_003486
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr10_+_17270469 1.086 VIM
vimentin
chr7_+_143078444 1.084 ZYX
zyxin
chr19_-_1512997 1.082 ADAMTSL5
ADAMTS-like 5
chr2_+_24272583 1.082 NM_004116
NM_054033
FKBP1B

FK506 binding protein 1B, 12.6 kDa

chr11_+_119076974 1.079 NM_005188
CBL
Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr22_-_28197469 1.075 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr17_-_6735007 1.073 NM_053285
TEKT1
tektin 1
chr1_+_15736387 1.072 NM_024329
EFHD2
EF-hand domain family, member D2
chr10_-_15210610 1.068 NM_004808
NMT2
N-myristoyltransferase 2
chr7_+_143078447 1.065 ZYX
zyxin
chr20_+_56884839 1.063 RAB22A
RAB22A, member RAS oncogene family
chr19_+_676346 1.063 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr9_-_132805456 1.058 NM_015033
FNBP1
formin binding protein 1
chr19_-_51472816 1.056 NM_002774
KLK6
kallikrein-related peptidase 6
chr2_+_210288668 1.053 NM_001039538
MAP2
microtubule-associated protein 2
chr1_-_38471170 1.052 NM_001243878
NM_004468
FHL3

four and a half LIM domains 3

chrX_-_132091223 1.051 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr7_-_94285372 1.046 SGCE
sarcoglycan, epsilon
chr19_-_40950238 1.044 NM_203344
SERTAD3
SERTA domain containing 3
chr19_+_41725098 1.044 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chr7_-_94285477 1.043 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr17_+_1959512 1.042 NM_001098202
HIC1
hypermethylated in cancer 1
chr6_-_41863086 1.040 NM_018561
USP49
ubiquitin specific peptidase 49
chr22_+_45148437 1.036 NM_001017526
NM_001198726
NM_181335
ARHGAP8


Rho GTPase activating protein 8


chr1_+_65886315 1.035 NM_001003679
NM_001003680
NM_002303
NM_001198681
LEPR


LEPROT
leptin receptor


leptin receptor overlapping transcript
chr1_+_3371020 1.032 NM_014448
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr22_+_50609159 1.031 NM_001160300
NM_052839
PANX2

pannexin 2

chr2_+_30454396 1.027 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr7_+_143078608 1.025 ZYX
zyxin
chr14_+_103589711 1.022 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr19_+_2096930 1.018 IZUMO4
IZUMO family member 4
chr15_+_90744506 1.014 NM_198925
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr7_+_143078457 1.010 ZYX
zyxin
chr8_-_131455833 1.009 NM_001247996
NM_018482
ASAP1

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

chr7_+_77166750 1.009 NM_002835
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr4_+_150999412 1.007 NM_001040260
NM_001040261
DCLK2

doublecortin-like kinase 2

chr9_+_33817168 1.001 NM_017811
UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr9_+_139971938 1.000 NM_207309
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr17_-_73840422 0.998 UNC13D
unc-13 homolog D (C. elegans)
chr22_-_26986041 0.993 TPST2
tyrosylprotein sulfotransferase 2
chr7_-_28220146 0.992 JAZF1
JAZF zinc finger 1
chr19_-_51456159 0.992 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr19_-_49339667 0.991 HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr11_+_65686727 0.989 NM_006442
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr3_+_50192420 0.984 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_-_231175971 0.984 NM_198552
FAM89A
family with sequence similarity 89, member A
chr19_-_4457789 0.983 NM_025241
UBXN6
UBX domain protein 6
chr5_-_180018465 0.981 NM_052863
SCGB3A1
secretoglobin, family 3A, member 1
chr11_+_46403260 0.981 MDK
midkine (neurite growth-promoting factor 2)
chr9_+_128509616 0.979 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr9_+_124922189 0.977 NM_198469
MORN5
MORN repeat containing 5
chr21_-_47648672 0.972 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr17_-_76124791 0.970 NM_001127198
TMC6
transmembrane channel-like 6
chr17_+_60704747 0.969 NM_006039
MRC2
mannose receptor, C type 2
chr20_+_33759773 0.967 NM_006404
PROCR
protein C receptor, endothelial
chr9_+_72435730 0.967 NM_001010940
C9orf135
chromosome 9 open reading frame 135
chr9_-_117156684 0.962 NM_030767
AKNA
AT-hook transcription factor
chr3_-_52090090 0.961 NM_001947
DUSP7
dual specificity phosphatase 7

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.09 1.04e-28 GO:0009987 cellular process
1.13 3.28e-21 GO:0050794 regulation of cellular process
1.12 9.02e-21 GO:0050789 regulation of biological process
1.12 6.68e-20 GO:0065007 biological regulation
1.13 7.90e-16 GO:0044237 cellular metabolic process
1.16 1.61e-15 GO:0044260 cellular macromolecule metabolic process
1.14 5.12e-13 GO:0043170 macromolecule metabolic process
1.11 8.95e-13 GO:0044238 primary metabolic process
1.10 9.64e-13 GO:0008152 metabolic process
1.24 2.39e-12 GO:0006464 protein modification process
1.22 6.13e-12 GO:0048523 negative regulation of cellular process
1.17 1.64e-11 GO:0016043 cellular component organization
1.16 4.13e-11 GO:0031323 regulation of cellular metabolic process
1.35 6.24e-11 GO:0051128 regulation of cellular component organization
1.19 1.07e-10 GO:0048522 positive regulation of cellular process
1.16 1.35e-10 GO:0060255 regulation of macromolecule metabolic process
1.14 1.66e-10 GO:0019222 regulation of metabolic process
1.16 2.33e-10 GO:0071840 cellular component organization or biogenesis
1.22 3.96e-10 GO:0043412 macromolecule modification
1.19 6.92e-10 GO:0048519 negative regulation of biological process
1.17 1.89e-09 GO:0048518 positive regulation of biological process
1.15 2.49e-09 GO:0080090 regulation of primary metabolic process
1.18 3.60e-09 GO:0044267 cellular protein metabolic process
1.13 1.02e-07 GO:0023052 signaling
1.23 1.18e-07 GO:0009966 regulation of signal transduction
1.21 2.81e-07 GO:0023051 regulation of signaling
1.31 4.41e-07 GO:0016192 vesicle-mediated transport
1.27 5.81e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.24 7.40e-07 GO:0010604 positive regulation of macromolecule metabolic process
1.55 8.28e-07 GO:0051129 negative regulation of cellular component organization
1.15 8.94e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 1.11e-06 GO:0007399 nervous system development
1.14 2.45e-06 GO:0019538 protein metabolic process
1.16 2.72e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.16 3.25e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.15 3.80e-06 GO:0009889 regulation of biosynthetic process
1.20 4.11e-06 GO:0009653 anatomical structure morphogenesis
1.15 4.61e-06 GO:0031326 regulation of cellular biosynthetic process
1.25 5.65e-06 GO:0032268 regulation of cellular protein metabolic process
1.13 6.29e-06 GO:0007165 signal transduction
1.15 1.14e-05 GO:0010468 regulation of gene expression
1.14 1.51e-05 GO:0071842 cellular component organization at cellular level
1.12 1.81e-05 GO:0007275 multicellular organismal development
1.22 1.85e-05 GO:0031325 positive regulation of cellular metabolic process
1.24 2.00e-05 GO:0006793 phosphorus metabolic process
1.24 2.00e-05 GO:0006796 phosphate metabolic process
1.21 2.08e-05 GO:0009893 positive regulation of metabolic process
1.17 2.44e-05 GO:0048583 regulation of response to stimulus
1.12 2.51e-05 GO:0051179 localization
1.28 2.85e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
1.38 3.02e-05 GO:0007264 small GTPase mediated signal transduction
1.11 3.20e-05 GO:0051716 cellular response to stimulus
1.22 4.90e-05 GO:0051246 regulation of protein metabolic process
1.14 5.11e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16 5.29e-05 GO:0030154 cell differentiation
1.11 5.35e-05 GO:0032502 developmental process
1.24 6.68e-05 GO:0022008 neurogenesis
1.25 7.63e-05 GO:0048699 generation of neurons
1.20 7.66e-05 GO:0035556 intracellular signal transduction
1.15 7.84e-05 GO:0065008 regulation of biological quality
1.59 1.06e-04 GO:0031344 regulation of cell projection organization
1.32 1.09e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.12 1.15e-04 GO:0006807 nitrogen compound metabolic process
1.13 1.17e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.29 1.17e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.29 1.19e-04 GO:0051726 regulation of cell cycle
1.28 1.27e-04 GO:0051254 positive regulation of RNA metabolic process
1.21 1.32e-04 GO:0044248 cellular catabolic process
1.15 1.42e-04 GO:0048869 cellular developmental process
1.13 1.55e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.17 2.04e-04 GO:0006996 organelle organization
1.20 2.07e-04 GO:0051641 cellular localization
1.28 2.21e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.12 2.28e-04 GO:0034641 cellular nitrogen compound metabolic process
1.27 2.75e-04 GO:0010628 positive regulation of gene expression
1.24 2.76e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.41 3.25e-04 GO:0030029 actin filament-based process
1.18 3.62e-04 GO:0009056 catabolic process
1.24 3.68e-04 GO:0009891 positive regulation of biosynthetic process
1.12 4.05e-04 GO:0048731 system development
1.28 4.44e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.23 4.63e-04 GO:0008219 cell death
1.25 5.46e-04 GO:0046907 intracellular transport
1.14 6.11e-04 GO:0051252 regulation of RNA metabolic process
1.23 6.23e-04 GO:0016265 death
1.27 6.71e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.16 7.59e-04 GO:0034645 cellular macromolecule biosynthetic process
1.24 8.49e-04 GO:0031399 regulation of protein modification process
1.21 8.72e-04 GO:0008104 protein localization
1.26 9.03e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.59 9.93e-04 GO:0022604 regulation of cell morphogenesis
1.42 1.03e-03 GO:0009166 nucleotide catabolic process
1.26 1.03e-03 GO:0019220 regulation of phosphate metabolic process
1.26 1.03e-03 GO:0051174 regulation of phosphorus metabolic process
1.26 1.05e-03 GO:0042325 regulation of phosphorylation
1.18 1.24e-03 GO:0033036 macromolecule localization
1.25 1.25e-03 GO:0009890 negative regulation of biosynthetic process
1.27 1.36e-03 GO:0001932 regulation of protein phosphorylation
1.59 1.57e-03 GO:0010975 regulation of neuron projection development
1.58 1.59e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.16 1.61e-03 GO:0009059 macromolecule biosynthetic process
1.30 1.63e-03 GO:0006753 nucleoside phosphate metabolic process
1.30 1.63e-03 GO:0009117 nucleotide metabolic process
1.24 1.65e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.42 1.76e-03 GO:0072523 purine-containing compound catabolic process
1.44 1.82e-03 GO:0009143 nucleoside triphosphate catabolic process
1.42 1.95e-03 GO:0006195 purine nucleotide catabolic process
1.11 1.96e-03 GO:0048856 anatomical structure development
1.22 2.33e-03 GO:0031324 negative regulation of cellular metabolic process
1.23 2.67e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.44 2.73e-03 GO:0009146 purine nucleoside triphosphate catabolic process
1.22 2.74e-03 GO:0006351 transcription, DNA-dependent
1.24 3.13e-03 GO:0012501 programmed cell death
1.21 3.25e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.43 3.57e-03 GO:0009261 ribonucleotide catabolic process
1.43 3.69e-03 GO:0009154 purine ribonucleotide catabolic process
1.43 3.95e-03 GO:0009203 ribonucleoside triphosphate catabolic process
1.43 3.95e-03 GO:0009207 purine ribonucleoside triphosphate catabolic process
1.19 4.05e-03 GO:0051649 establishment of localization in cell
1.33 4.26e-03 GO:0044419 interspecies interaction between organisms
1.19 4.39e-03 GO:0010646 regulation of cell communication
1.40 4.89e-03 GO:0000165 MAPKKK cascade
1.38 5.06e-03 GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
1.38 5.06e-03 GO:0034656 nucleobase, nucleoside and nucleotide catabolic process
1.20 5.49e-03 GO:0042127 regulation of cell proliferation
1.50 5.76e-03 GO:0046039 GTP metabolic process
1.59 6.03e-03 GO:0031098 stress-activated protein kinase signaling cascade
1.28 6.05e-03 GO:0007010 cytoskeleton organization
1.11 6.17e-03 GO:0006810 transport
1.23 6.77e-03 GO:0006468 protein phosphorylation
1.11 6.82e-03 GO:0051234 establishment of localization
1.30 7.45e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.13 7.79e-03 GO:0006355 regulation of transcription, DNA-dependent
1.24 8.62e-03 GO:0009790 embryo development
1.38 9.07e-03 GO:0001568 blood vessel development
1.51 9.29e-03 GO:0006184 GTP catabolic process
1.56 9.96e-03 GO:0007265 Ras protein signal transduction
1.34 1.03e-02 GO:0009150 purine ribonucleotide metabolic process
1.43 1.04e-02 GO:0045664 regulation of neuron differentiation
1.12 1.06e-02 GO:0044249 cellular biosynthetic process
1.19 1.10e-02 GO:0009892 negative regulation of metabolic process
1.38 1.26e-02 GO:0030036 actin cytoskeleton organization
1.21 1.29e-02 GO:0016310 phosphorylation
1.23 1.31e-02 GO:0006915 apoptosis
1.29 1.31e-02 GO:0048812 neuron projection morphogenesis
1.27 1.32e-02 GO:0000904 cell morphogenesis involved in differentiation
1.33 1.42e-02 GO:0007411 axon guidance
1.28 1.44e-02 GO:0072358 cardiovascular system development
1.28 1.44e-02 GO:0072359 circulatory system development
1.23 1.45e-02 GO:0030182 neuron differentiation
1.36 1.48e-02 GO:0001944 vasculature development
1.27 1.54e-02 GO:0048858 cell projection morphogenesis
1.26 1.59e-02 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.28 1.82e-02 GO:0061024 membrane organization
1.33 1.83e-02 GO:0009259 ribonucleotide metabolic process
1.28 1.84e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.28 1.91e-02 GO:0016044 cellular membrane organization
1.27 1.98e-02 GO:0043549 regulation of kinase activity
1.26 2.08e-02 GO:0051338 regulation of transferase activity
1.38 2.08e-02 GO:0001558 regulation of cell growth
1.26 2.19e-02 GO:0032990 cell part morphogenesis
1.23 2.35e-02 GO:0030030 cell projection organization
1.35 2.43e-02 GO:0061061 muscle structure development
1.19 2.45e-02 GO:0032879 regulation of localization
1.13 2.61e-02 GO:0010467 gene expression
1.29 2.79e-02 GO:0007409 axonogenesis
1.23 2.86e-02 GO:0032989 cellular component morphogenesis
1.33 2.92e-02 GO:0044270 cellular nitrogen compound catabolic process
1.27 3.08e-02 GO:0045859 regulation of protein kinase activity
1.33 3.21e-02 GO:0009141 nucleoside triphosphate metabolic process
1.11 3.68e-02 GO:0009058 biosynthetic process
1.19 3.68e-02 GO:0048468 cell development
1.22 3.70e-02 GO:0045595 regulation of cell differentiation
1.28 4.00e-02 GO:0016477 cell migration
1.20 4.06e-02 GO:0033554 cellular response to stress
1.12 4.38e-02 GO:0090304 nucleic acid metabolic process
1.28 4.63e-02 GO:0009968 negative regulation of signal transduction
1.28 4.75e-02 GO:0072521 purine-containing compound metabolic process
1.23 4.76e-02 GO:0000902 cell morphogenesis
1.33 4.97e-02 GO:0009144 purine nucleoside triphosphate metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 8.36e-41 GO:0005622 intracellular
1.10 4.16e-40 GO:0044424 intracellular part
1.14 2.81e-38 GO:0005737 cytoplasm
1.12 1.19e-28 GO:0043227 membrane-bounded organelle
1.12 1.40e-28 GO:0043231 intracellular membrane-bounded organelle
1.10 1.03e-27 GO:0043226 organelle
1.10 1.96e-27 GO:0043229 intracellular organelle
1.15 2.19e-23 GO:0044444 cytoplasmic part
1.13 5.43e-16 GO:0044446 intracellular organelle part
1.13 1.63e-15 GO:0044422 organelle part
1.22 2.99e-13 GO:0044428 nuclear part
1.12 1.45e-12 GO:0005634 nucleus
1.21 2.20e-12 GO:0005829 cytosol
1.22 2.02e-11 GO:0031981 nuclear lumen
1.19 1.57e-10 GO:0070013 intracellular organelle lumen
1.19 2.14e-10 GO:0043233 organelle lumen
1.19 2.91e-10 GO:0031974 membrane-enclosed lumen
1.29 7.94e-10 GO:0005794 Golgi apparatus
1.24 1.98e-09 GO:0005654 nucleoplasm
1.33 5.22e-07 GO:0044431 Golgi apparatus part
1.19 9.35e-07 GO:0012505 endomembrane system
1.03 1.95e-06 GO:0044464 cell part
1.03 2.16e-06 GO:0005623 cell
1.12 1.94e-05 GO:0043234 protein complex
1.40 3.56e-05 GO:0015629 actin cytoskeleton
1.15 4.17e-05 GO:0031090 organelle membrane
1.24 8.50e-05 GO:0031982 vesicle
1.24 1.54e-04 GO:0031410 cytoplasmic vesicle
1.30 2.24e-04 GO:0000139 Golgi membrane
1.21 4.30e-04 GO:0042995 cell projection
1.92 2.29e-03 GO:0008287 protein serine/threonine phosphatase complex
1.43 3.92e-03 GO:0030424 axon
1.21 4.18e-03 GO:0044451 nucleoplasm part
1.09 7.36e-03 GO:0032991 macromolecular complex
1.21 7.43e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.60 8.36e-03 GO:0030027 lamellipodium
1.20 9.24e-03 GO:0031988 membrane-bounded vesicle
1.26 1.05e-02 GO:0005768 endosome
1.27 1.10e-02 GO:0043005 neuron projection
1.30 1.30e-02 GO:0005773 vacuole
1.29 1.50e-02 GO:0048471 perinuclear region of cytoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 1.58e-44 GO:0005515 protein binding
1.09 3.29e-34 GO:0005488 binding
1.49 1.23e-12 GO:0019904 protein domain specific binding
1.17 6.71e-08 GO:0000166 nucleotide binding
1.18 3.84e-07 GO:0032553 ribonucleotide binding
1.18 3.84e-07 GO:0032555 purine ribonucleotide binding
1.18 5.74e-07 GO:0017076 purine nucleotide binding
1.09 1.56e-06 GO:0003824 catalytic activity
1.17 2.32e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.18 4.28e-06 GO:0016740 transferase activity
1.25 7.40e-06 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.26 8.66e-06 GO:0016301 kinase activity
1.27 1.60e-05 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.25 1.73e-04 GO:0019899 enzyme binding
1.29 2.02e-04 GO:0008092 cytoskeletal protein binding
1.24 4.24e-04 GO:0042802 identical protein binding
1.16 4.91e-04 GO:0032559 adenyl ribonucleotide binding
1.16 5.48e-04 GO:0030554 adenyl nucleotide binding
1.25 9.32e-04 GO:0004672 protein kinase activity
1.36 1.59e-03 GO:0008134 transcription factor binding
1.19 2.22e-03 GO:0030528 transcription regulator activity
1.15 3.18e-03 GO:0005524 ATP binding
1.28 3.78e-03 GO:0030695 GTPase regulator activity
1.27 4.44e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.30 4.91e-03 GO:0000988 protein binding transcription factor activity
1.30 4.91e-03 GO:0000989 transcription factor binding transcription factor activity
1.30 6.46e-03 GO:0003712 transcription cofactor activity
1.39 8.63e-03 GO:0003924 GTPase activity
1.27 8.82e-03 GO:0004674 protein serine/threonine kinase activity
1.21 1.57e-02 GO:0043565 sequence-specific DNA binding
1.52 1.70e-02 GO:0017124 SH3 domain binding
1.21 1.94e-02 GO:0046983 protein dimerization activity
1.17 2.12e-02 GO:0001071 nucleic acid binding transcription factor activity
1.17 2.12e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.31 2.34e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.17 3.07e-02 GO:0030234 enzyme regulator activity
1.36 3.21e-02 GO:0003713 transcription coactivator activity
1.29 3.59e-02 GO:0003779 actin binding
1.29 4.16e-02 GO:0016563 transcription activator activity